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Name of drug Classificat ion Mechanism of action Indication Contraindication Adverse reactions Nsg. reposnsibilitie s Generic name Divalproex Sodium Trade name Depakote Anticonvuls ant & mood stabilizing drug Unknown , probably facilitates the effects of the inhibitory neurotransmit ter GABA. Simple and complex absences seizures -complex partial seizures -mania -prevent migraine headache Pregnancy Pre-existing acute or chronic liver dysfunction or family history of severe liver inflammation (hepatitis) , particularly medicine related. Known hypersensitivity to valproate or any of the excipients used in the preparation Urea cycle disorders Hepatic porphyria Hepatotoxicity Mitochondrial disease Pancreatitis Diarrhea, dizziness, drowsiness, hair loss, blurred/double vision, change in menstrual periods, ringing in the ears, shakiness (tremor), unsteadiness, weight changes may occur Before: check with prescriber, tell patient to take drugs with food or milk. During : Dont give syrup to patient who ned sodium restriction Advise pt. Not to chew the capsule may result mouth and throat irritation. After : instruct patient or call physician if malaise ,weakne ss lethargy facial swelling , loss of appetite or

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Name of drug Classifcation Mechanism ofactionIndication Contraindication AdversereactionsNsg.reposnsibilitiesGeneric nameDivalproexSodiumrade name Depa!oteAnticonvulsant" moodstabili#ingdrug$n!no%n &probabl'facilitates thee(ects of theinhibitor'neurotransmitter GA)A.Simple andcomplex absencessei#ures*complex partialsei#ures*mania*prevent migraineheadache+regnanc'+re*existing acute or chronicliver d'sfunction or famil'histor' of severe liverin,ammation -hepatitis.&particularl' medicinerelated./no%n h'persensitivit' tovalproate or an' of theexcipients used in thepreparation$rea c'cle disorders0epatic porph'ria0epatotoxicit'Mitochondrial disease+ancreatitisDiarrhea&di##iness&dro%siness& hairloss&blurred1doublevision& changeinmenstrualperiods& ringingin the ears&sha!iness-tremor.&unsteadiness&%eight changesma' occur)efore2 chec! %ithprescriber& tellpatient to ta!edrugs %ith food ormil!.During 2 Dontgive s'rup topatient %ho nedsodium restrictionAdvisept. Not toche%thecapsulema'result mouthand throatirritation.After 2 instructpatient or callph'sician ifmalaise&%ea!nessletharg' facials%elling & loss ofappetite orvomiting occurs.Name of drug Classifcation Mechanism of action Indication Contraindication Adverse e(ect NSG.responsibilitiesGeneric nameceteri#ineAntihistamine Cetiri#ine& ahumanmetabolite ofh'drox'#ine& is anantihistamine3 itsprincipal e(ectsaremediated viaselective inhibitionof peripheral 04receptors.Seasonalallergic rhinitis*perineal allergicrhinitis*chronic uticariaContraindicated in pth'persensitive todrug or toh'drox'#ineAnd breast feeding%omen$secautiousl'inpt%ith renalor hepaticimpairmentDro%siness&excessivetiredness& dr'mouth& sorethroat& di##iness)efore2Advise pt not tousealcohol orcnsdepressant %hileta!ing the drugsell pt that co(eeor tea ma' reducedro%sinessDuring2Give medication asprescribed*avoidalcohol andco(ee* inform pt thatsugarless gum&hardcand'or icechips ma' relievefr' mouthAfter notif'ph'sician ifadverse reactionpersist