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My Worst Venous Complication Daniela Branzan, MD, Department of Vascular Surgery University Hospital Leipzig

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Page 1: My Worst Venous Complication - Login - NMSuite

My Worst Venous Complication

Daniela Branzan, MD,

Department of Vascular Surgery

University Hospital Leipzig

Page 2: My Worst Venous Complication - Login - NMSuite

Disclosure

I do not have any potential conflict of interest.

Page 3: My Worst Venous Complication - Login - NMSuite

Clinical Findings

• 18-year-old man

• back pain

• worsening painful swelling in his both legs, severely limiting his mobility within the last 3 weeks

• no shortness of breath, cough or chest pain,

• afebrile and HD stable

• past medical history unremarkable

Page 4: My Worst Venous Complication - Login - NMSuite

Clinical Findings

• no familial history for venous thromboembolism

• US: extensive clot, with complete occlusion of the external iliac vein, and common, deep and superficial femoral veins

• CT pulmonary angiogram excluded pulmonary embolism (PE).

Page 5: My Worst Venous Complication - Login - NMSuite

CT scan of the abdomen (coronal view)

extensive thrombosis of the IVC

Page 6: My Worst Venous Complication - Login - NMSuite

CT scan of the abdomen

Infrarenal IVC extensively thrombosed

Thrombosis of the CIV, EIV on both sides Patent renal veins

Page 7: My Worst Venous Complication - Login - NMSuite

CT scan of the abdomen

marked hypoplasia of the intrahepatic tract of the IVC

Venous drainage from the inferior part of the body

accomplished by a dilated azygos and paravertebral

veins

Intrahepatic IVC thrombosed

Page 8: My Worst Venous Complication - Login - NMSuite

Subacute IVC Thrombosis

Treatment Modalities

• Anticoagulation alone->disabling PTS

• CDT

• Phamacomechanical catheter directedthrombolysis

• PTA and Stenting

Page 9: My Worst Venous Complication - Login - NMSuite

Intervention # 1

Page 10: My Worst Venous Complication - Login - NMSuite

Mechanical Thrombus Removal(10,5 Fr. Aspirex, Straub Medical AG)

Page 11: My Worst Venous Complication - Login - NMSuite

Cragg-McNamara (Medtronic, Minneapolis, Minn) infusion catheters inserted through each popliteal vein

Alteplase (10 mg mixed in 1,000 ml of 0.9% NaCl), infused at a rate of 0.01 mg/kg/h

Page 12: My Worst Venous Complication - Login - NMSuite

Intervention # 2: 24 h later

Page 13: My Worst Venous Complication - Login - NMSuite

Mechanical Thrombus Removal(10,5 Fr. Aspirex)

Page 14: My Worst Venous Complication - Login - NMSuite

PTA of a suprarenal collateral

Page 15: My Worst Venous Complication - Login - NMSuite

Significant residual stenosis due to the chronicity of the thrombosis of CIV&IVC

Good Flow in the Azygos System

Page 16: My Worst Venous Complication - Login - NMSuite

3 Days later

• Symptomatic Re-Occlusion of IVC, iliac Veins. CFV, VF on both sides despite

– anticoagulation with UFH and

– graduated compression stockings

Page 17: My Worst Venous Complication - Login - NMSuite

Intervention # 3: 4 Days later

Page 18: My Worst Venous Complication - Login - NMSuite

Iliofemoral Thrombectomy

Femoral venotomy and surgical thrombectomy: combination of acute soft thrombus and a chronic fibrotic thrombus

Page 19: My Worst Venous Complication - Login - NMSuite

Surgical Thrombectomy

Page 20: My Worst Venous Complication - Login - NMSuite

IVC and CIV Flow after Thrombectomy

Page 21: My Worst Venous Complication - Login - NMSuite

CART of IVC Occlusion via IJV and CFVEstablish a through-and-through wire

Page 22: My Worst Venous Complication - Login - NMSuite

High Preassure PTA of the IVC Occlusion(Conquest® 40 - Bard PV )

Page 23: My Worst Venous Complication - Login - NMSuite

Sinus XL 22/100, 22/80mm(Optimed)

Page 24: My Worst Venous Complication - Login - NMSuite

Surgical Thrombectomy of left CIV

Page 25: My Worst Venous Complication - Login - NMSuite

Final Phlebography

Page 26: My Worst Venous Complication - Login - NMSuite

Discharge

• Graduated compression stockings

• Ass 100mg/die, Clopidogrel 75mg/die for 1 month, NOAK

Page 27: My Worst Venous Complication - Login - NMSuite

• Collateral veins on the left side of the abdomen

• Small varicose veins on the calf

• Discrete edema BTK

• Plays Volleyball regularly

FU@4 Mo

Page 28: My Worst Venous Complication - Login - NMSuite

Phlebography@4 Mo

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Phlebography@4 Mo

Page 30: My Worst Venous Complication - Login - NMSuite

Things we might have considered to improve Patency

• Stenting across the iliocaval bifurcation?

• IVUS?

• AV-Fistula at the groin?

• Inferior vena cava thrombectomy?

Page 31: My Worst Venous Complication - Login - NMSuite

Thank you!

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[email protected]

Page 32: My Worst Venous Complication - Login - NMSuite

My Worst Venous Complication

Daniela Branzan, MD,

Department of Vascular Surgery

University Hospital Leipzig