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    DIGESTIVESYSTEM and

    BODY

    METABOLISM

    Alyssa Ashley R.

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    y y

    THE DIGESTIVE SYSTEM

    AND BODY METABOLISM Digestion

    Breakdown of ingested food

    Absorption

    Passage of nutrients into theblood

    Metabolism

    Production of cellular energy

    (ATP)

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    ORGANS OF THE

    DIGESTIVE SYSTEM Two main groups

    1. Alimentary canal

    - continuous coiled

    hollow tube

    2. Accessory digestive organs

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    CANAL

    Mouth Pharynx

    Esophagus Stomach

    Small intestine Large intestine

    Anus

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    ANATOMY

    Lips (labia) protect the anterioropening

    Cheeks form the lateral walls

    Hard palate forms the anteriorroof

    Soft palate forms the posteriorroof

    Uvula fleshy projection of the

    soft palate

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    ANATOMY

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    ANATOMY

    Vestibule space between lipsexternally and teeth and gumsinternally

    Oral cavity area contained bythe teeth

    Tongue attached at hyoid andstyloid processes of the skull,

    and by the lingual frenulum

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    ANATOMY

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    ANATOMY Tonsils

    Palatine

    tonsil

    Lingualtonsil

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    MOUTH Mastication (chewing) of food

    Mixing masticated food with

    saliva Initiation of swallowing by the

    tongue Allowing for the sense of taste

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    PHARYNX ANATOMY

    Nasopharynx not part of the digestive system

    Oropharynx posterior to oralcavity

    Laryngopharynx below the

    oropharynx and connected tothe esophagus

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    PHARYNXANATOMY

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    PHARYNX FUNCTIONS

    Serves as a passageway for air andfood

    Food is propelled to the esophagus by

    two muscle layersLongitudinal inner layer

    Circular outer layer

    Food movement is by alternating

    contractions of the muscle layers

    (peristalsis)

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    ESOPHAGUS

    Runs from pharynx tostomach through the

    diaphragm Conducts food by peristalsis

    (slow rhythmic squeezing)

    Passageway for food only

    (respiratory system branches

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    LAYERS OF ALIMENTARY

    CANAL ORGANS1. Mucosa

    Innermost layer

    Moist membrane

    Surface epithelium

    Small amount of connectivetissue (lamina propria)

    Small smooth muscle layer

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    LAYERS OF ALIMENTARY

    CANAL ORGANS2. Submucosa

    Just beneath the mucosaSoft connective tissue with

    blood vessels, nerve endings,

    and lymphatics

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    ORGANS

    3. Muscularis externa smoothmuscle

    Inner circular layer

    Outer longitudinal layer4. Serosa

    Outermost layer visceralperitoneum

    Layer of serous fluid-producing

    cells

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    STOMACH ANATOMY

    Located on the left side ofthe abdominal cavity

    Food enters at thecardioesophageal sphincter

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    STOMACH ANATOMY

    Regions of the stomachCardiac region near the heart

    Fundus

    Body

    Pylorus funnel-shaped terminal

    end

    Food empties into the small

    intestine at the pyloric sphincter

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    STOMACH ANATOMY

    Rugae internal folds of themucosa

    External regions

    Lesser curvature

    Greater curvature

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    STOMACH ANATOMY

    Layers of peritoneum attached tothe stomach

    Lesser omentum attaches the

    liver to the lesser curvatureGreater omentum attaches the

    greater curvature to the posteriorbody wall

    Contains fat to insulate, cushion,

    and protect abdominal organs

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    STOMACH ANATOMY

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    STOMACH FUNCTIONS

    Acts as a storage tank forfood

    Site of food breakdown Chemical breakdown of

    protein begins Delivers chyme (processed

    food) to the small intestine

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    (STOMACH) Simple columnar epitheliumMucous neck cells produce a

    sticky alkaline mucus

    Gastric glands secrete gastricjuice

    Chief cells produce protein-

    digesting enzymes(pepsinogens)

    Parietal cells produce

    hydrochloric acid

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    STRUCTURE

    Gastric pits formed byfolded mucosa

    Glands and specializedcells are in the gastric gland

    region

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    STRUCTURE

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    SMALL INTESTINE

    The bodys major digestive organ Site of nutrient absorption into the

    blood

    Muscular tube extending from the

    pyloric sphincter to the ileocecal

    valve Suspended from the posterior

    abdominal wall by the mesentery

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    SUBDIVISIONSDOGS JUST ITCH! DuodenumAttached to the stomachCurves around the head of the

    pancreas JejunumAttaches anteriorly to the

    duodenum IleumExtends from jejunum to large

    intestine

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    CHEMICAL DIGESTION

    (SMALL INSTESTINE) Source of enzymes that are

    mixed with chymeIntestinal cells

    Pancreas Bile enters from the gall

    bladder

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    CHEMICAL DIGESTION

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    VILLI OF THE SMALL

    INTESTINE Fingerlike structures formed

    by the mucosa Give the small intestine

    more surface area

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    INTESTINE

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    MICROVILLI OF THE

    SMALL INTESTINE Small

    projections ofthe plasma

    membrane

    Found on

    absorptive

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    IN ABSORPTION OF

    NUTRIENTS Absorptivecells

    Bloodcapillaries

    Lacteals(specialized

    lymphatic

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    FOLDS OF THE SMALL

    INTESTINE Called circular folds Deep folds of the mucosa and

    submucosa Do not disappear when filled

    with food

    The submucosa has Peyerspatches (collections of

    lymphatic tissue)

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    INTESTINE Enzymes from the brush border

    Break double sugars into simplesugars

    Complete some protein digestion

    Pancreatic enzymes play themajor digestive function

    Help complete digestion ofstarch (pancreatic amylase)

    Carry out about half of all protein

    digestion (trypsin, etc.)

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    INTESTINE

    Pancreatic enzymes play themajor digestive function

    (continued)

    Responsible for fat digestion(lipase)

    Digest nucleic acids(nucleases)

    Alkaline content neutralizes

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    INTESTINE Water is absorbed along the length of

    the small intestine

    End products of digestion

    Most substances are absorbed byactive transport through cellmembranes

    Lipids are absorbed by diffusion Substances are transported to theliver by the hepatic portal vein or

    lymph

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    INTESTINE

    Peristalsis is the major meansof moving food

    Segmental movements

    Mix chyme with digestive

    juices

    Aid in propelling food

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    LARGE INTESTINE

    Larger in diameter, butshorter than the small

    intestine Frames the internal

    abdomen

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    LARGE INTESTINE

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    FUNCTIONS Absorption of water Eliminates indigestible food

    from the body as feces Does not participate in

    digestion of food

    Goblet cells produce mucus to

    act as a lubricant

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    STRUCTURES

    Cecum saclike first part of thelarge intestine

    Appendix

    Accumulation of lymphatic tissue

    that sometimes becomes

    inflamed (appendicitis)Hangs from the cecum

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    STRUCTURES

    ColonAscending Colon

    Transverse ColonDescending Colon

    S-shaped sigmoidal Colon

    Rectum

    Anus external body opening

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    ABSORPTION IN THE LARGE

    INTESTINE No digestive enzymes areproduced

    Resident bacteria digest remainingnutrientsProduce some vitamin K and B

    Release gases Water and vitamins K and B areabsorbed

    Remaining materials are

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    INTESTINE Sluggish peristalsis

    Mass movementsSlow, powerful movementsOccur three to four times per day

    Presence of feces in the rectumcauses a defecation reflexInternal anal sphincter is relaxed

    Defecation occurs withrelaxation of the voluntary(external) anal sphincter

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    ORGANS

    Salivary glands Teeth

    Pancreas Liver

    Gall bladder

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    SALIVA

    Mixture of mucus and serousfluids

    Helps to form a food bolus Contains salivary amylase to

    begin starch digestion

    Dissolves chemicals so they

    can be tasted

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    TEETH

    The role is to masticate (chew)food

    Humans have two sets of teethDeciduous (baby or milk)

    teeth

    20 teeth are fully formed by

    age two

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    TEETH

    Permanent teethReplace deciduous teeth

    beginning between theages of 6 to 12

    A full set is 32 teeth, butsome people do not have

    wisdom teeth

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    CLASSIFICATION Incisors Canines

    Premolars

    Molars

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    CLASSIFICATION

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    TOOTH REGIONS Crown exposed part

    Outer enamelDentinPulp cavity

    NeckRegion in contact with the gumConnects crown to root

    RootPeriodontal membrane attached tothe bone

    Root canal carrying blood vessels

    and nerves

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    TOOTH REGIONS

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    PANCREAS Produces a wide spectrum of

    digestive enzymes that breakdown all categories of food

    Enzymes are secreted into theduodenum

    Alkaline fluid introduced withenzymes neutralizes acidic chyme

    Endocrine products of pancreas

    Insulin

    Glucagons

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    LIVER Largest gland in the body

    Located on the right side of thebody under the diaphragm

    Consists of four lobessuspended from the diaphragmand abdominal wall by the

    falciform ligament Connected to the gall bladder

    via the common hepatic duct

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    BILE Produced by cells in the liver

    Composition

    Bile salts

    Bile pigment (mostly bilirubinfrom the breakdown ofhemoglobin)

    CholesterolPhospholipids

    Electrolytes

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    METABOLISM

    Several roles in digestion Detoxifies drugs and alcohol

    Degrades hormones

    Produce cholesterol, bloodproteins (albumin and clotting

    proteins) Plays a central role in

    metabolism

    GALLBLADDER

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    GALLBLADDER

    Sac found in hollow fossa ofliver

    Stores bile from the liver by

    way of the cystic duct

    Bile is introduced into the

    duodenum in the presence offatty food

    Gallstones can cause

    PROCESSES OF

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    PROCESSES OF

    DIGESTIVE SYSTEM Ingestion getting food into themouth

    Propulsion moving foods fromone region of the digestive systemto another

    Peristalsis alternating waves ofcontraction

    Segmentation moving materials

    back and forth to aid in mixing

    PROCESSES OF

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    PROCESSES OF

    DIGESTIVE SYSTEM

    PROCESSES OF

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    PROCESSES OF

    DIGESTIVE SYSTEM Mechanical digestion

    Mixing of food in the mouth bythe tongue

    Churning of food in the

    stomachSegmentation in the small

    intestine

    PROCESSES OF

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    PROCESSES OF

    DIGESTIVE SYSTEM Chemical DigestionEnzymes break down food

    molecules into their building blocks

    Each major food group usesdifferent enzymesCarbohydrates are broken to

    simple sugarsProteins are broken to aminoacids

    Fats are broken to fatty acids and

    PROCESSES OF

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    PROCESSES OF

    DIGESTIVE SYSTEM AbsorptionEnd products of digestion are

    absorbed in the blood or lymphFood must enter mucosal cellsand then into blood or lymphcapillaries

    Defecation

    Elimination of indigestible

    substances as feces

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    CONTROL OF DIGESTIVE

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    CONTROL OF DIGESTIVE

    ACTIVITY Mostly controlled by reflexesvia the parasympathetic

    division

    Chemical and mechanical

    receptors are located in organwalls that trigger reflexes

    CONTROL OF DIGESTIVE

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    CONTROL OF DIGESTIVE

    ACTIVITY Stimuli include:Stretch of the organ

    pH of the contentsPresence of breakdown products

    Reflexes include:

    Activation or inhibition ofglandular secretions

    Smooth muscle activity

    NUTRITION

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    NUTRITION Nutrient substance used by the

    body for growth, maintenance, andrepair Categories of nutrients

    Carbohydrates: simple sugars,starches, fiberLipids: triglycerides, phospholipids,

    fatty acids

    Proteins: amino acidsVitaminsMineral

    BODY ENERGY BALANCE

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    BODY ENERGY BALANCE Energy intake = total energy

    output (heat + work + energystorage)

    Energy intake is liberatedduring food oxidation

    Energy output

    Heat is usually about 60%Storage energy is in theform of fat or glycogen