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    Symptoms of Cardiac &

    Respiratory Diseases

    Metabolism Department

    Alexandria University

    Mohammed Zeitoun

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    Dyspnea

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    Subjective feeling of difficulty in breathing

    concerning the rate, rhythm or depth of

    respiration.

    Dyspnea

    Definition:

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    How do the patient describe dyspnea

    Cannot get enough air.

    Air does not go all the way down.

    Tightness in the chest.

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    Grade I: Difficulty of breathing on doing MORE

    than the usual daily effort (Physiological).

    Grade II: Difficulty of breathing on doing the

    usual daily effort.

    Grade III: Difficulty of breathing on doing LESS

    than the usual daily effort.

    Grade IV: Difficulty of breathing at rest.

    Grades of Dyspnea

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    With Exercise.

    Causes of Dyspnea

    Physiological:

    Cardiac Causes: e.g. Left Heart Failure, PericardialEffusion.

    Pathological:

    Pulmonary Causes: ANY Chest Disease e.g.Pneumonia, Bronchial Asthma, Lung Collapse,

    Pulmonary Fibrosis, Pulmonary Embolism, . .

    History of emotional stress, commonly in females.

    Diagnosed by Exclusion of Organic Causes.

    Psychogenic: (Hysterical)

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    Causes of Dyspnea

    Pulmonary

    Pulmonary embolism

    Obstructive lung disease

    Interstitial lung disease

    Pleural effusion

    Pneumonia

    Acute Bronchitis

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    Toxic dyspnea

    The overdose of morphine and pentobarbital candepress respiratory center causing slow respiration.

    Haematologicl dyspnea

    The decrease of oxygen-carrying capacity and

    oxygen content develop abnormal respiration and

    increase heart rate, such as severe anemia,carbon monoxide.

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    Differential Diagnosis

    Composed of four general categories

    Cardiac

    Pulmonary

    Mixed cardiac or pulmonary

    non-cardiac or non-pulmonary

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    Noncardiac or NonpulmonaryEtiology

    Metabolic conditions (e.g. acidosis)

    Pain

    Trauma

    Neuromuscular disorders

    Functional(anxiety,panic disorders,

    hyperventilation)

    Chemical exposure

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    Accompanying symptoms

    Paroxysmal dyspnea with wheezing

    It is present in: Bronchial asthma.

    Cardiac asthma.

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    Accompanying symptoms

    Dyspnea with chest pain

    It is frequently observed in:

    Lobar pneumonia.

    Pulmonary infarction.

    Spontaneous pneumothorax.

    Acute myocardial infarction.

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    Accompanying symptoms

    Dyspnea with fever

    It is frequently observed in:

    Pneumonia

    Lung abscess.

    Pleurisy

    Acute pericarditis

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    Accompanying symptoms

    Dyspnea with cough & purulent sputum

    It is frequently observed in:

    Chronic bronchitis.

    Emphysema.

    Purulent pneumonia

    Lung abscess.

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    Accompanying symptoms

    Dyspnea with large amount of

    foamy sputum

    is often seen in:

    Acute left ventricular heart failure

    Organo-phosphorus poisoning.

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    Orthopnea

    Definition: Difficulty in breathing in the supineposition; relived by sitting up.

    Mechanism: Reduce the degree of pulmonary congestion by

    pooling blood in the lower extremities

    Improve the diaphragmatic movement

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    Orthopnea

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    Paroxysmal nocturnal dyspnea

    Definition: respiratory distress that awakenspatients from sleep in hunger to air (usually

    occurs 2 to 4 hours after onset of sleep) compelsthe patient to sit upright or stand.

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    In cases where test results inconclusive

    Complete PFTs

    ABGs

    EKG

    Exercise treadmill testing.

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    There is no single specific treatment for dyspnea.

    Treatment varies according to patients condition

    Chief complaint.

    History.

    Exam.

    Laboratory & radiological study results.

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    Chest Pain

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    Site.

    Radiation. Character.

    Duration.

    Precipitating Factors.

    Relieving Factors.

    Associated Symptoms.

    Chest Pain

    Comment on Chest pain:

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    Site: Retrosternal.

    Radiation: Left Shoulder, Left Arm, neck or jaw. Character: Tightness, heaviness or Squeezing.

    Duration: Minutes

    Precipitating Factors: Exercise or Emotional Stress

    Relieving Factors: Rest or SL Nitroglycerine

    Associated Symptoms: Sweating & Palpitation

    Chest Pain

    e.g. Anginal Pain:

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    A careful history is the single most important

    means of diagnosing angina.

    The typical patient is a middle-aged or elderly

    man or woman with one or more of the cardio-

    vascular risk factors (smoking, hypertension or

    dyslipidemia)

    Chest Pain

    e.g. Anginal Pain:

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    CHD: Angina Pectoris & Myocardial Infarction.

    Pericarditis.

    Dissecting Aortic Aneurysm.

    Causes of Chest Pain

    Cardiac Causes:

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    Chest Wall: e.g. Fracture Ribs, Myositis, Neuralgia.

    Pleuro-Pulmonary: e.g. Pleurisy, Pneumothorax,Pulmonary Embolism.

    Mediastinum: e.g. Mediastinitis, Oesophageal

    malignancy, Oesophageal Spasm.

    Diaphragm: e.g. hiatus Hernia

    Abdomen: e.g. Cholecystitis, Subphrenic Abscess.

    Causes of Chest Pain

    Non-Cardiac Causes:

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    Palpitation

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    syncope

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    Cardiac syncope

    Syncope is a sudden transient loss of

    consciousness and postural tone with

    spontaneous recovery.

    Restoration of appropriate behavior andorientation after a syncopal episode is usually

    immediate.

    Retrograde amnesia is uncommon.

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    Cardiac syncope

    Syncope is an important clinical problem because it is a

    common, costly, often disabling, may cause injury, and

    may be the only warning sign before sudden cardiac

    death ( SCD).

    Neuro-cardiogenic syncope may have an early warning

    (nausea , yawning).

    The patient appears pale and diaphoretic, and revive

    more slowly, without signs of seizure or a prolongedpost-ictal state.

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    Cough

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    Cough is an explosive expiratory maneuver that isreflexively intended to clearthe airways.

    Coughing is a normal response to the presence ofmucus or other foreign material in the airway or

    upper airway, but persistent coughing is annoying

    and generally indicates irritation of the pulmonary

    airways.

    Cough is a deep expiratory effort against a closedglottis, which opens suddenly, with a jet of air.

    Cough

    Definition:

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    It brings out sputum.

    It should not be suppressed.

    Types of Cough

    Productive Cough:

    It brings no sputum.

    It should be suppressed as it is useless.

    Dry Cough:

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    Cough

    How long had the cough been present?

    Is the cough worse at any time of day or

    night?

    Dry cough at night bronchial asthma? Is the cough aggravated by anything, for

    example dust pollen or cold air?

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    Evaluation of Cough

    URI and sinus symptoms suggest postnasal dripsyndrome, but postnasal drip can causes cough

    without other symptoms.

    Heartburn, hoarseness, and chronic nocturnal or earlymorning cough, especially if no other symptoms arepresent, suggests GERD.

    Cough after exposure to dusts or allergens suggests

    Bronchial Asthma. Chronic cough with production of purulent sputum in

    smokers suggests Chronic Bbronchitis. A change in

    cough in these patients may, however, be an early

    manifestation ofLung Cancer.

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    It is the passage of sputum out of the

    respiratory tract.

    Expectoration

    Definition:

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    Expectoration

    Is sputum produced?

    What does it look like?

    How much is produced?

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    Per 24 hours e.g. 5CC, 15CC, 30CC, 100CC,200CC.

    Comment on Expectoration

    Amount:

    Yellowish: Bacterial infection e.g. Streptococci

    Colour:

    Fetid sputum indicates infection with anaerobicbacteria.

    Odour:

    Greenish: Pseudomonas.

    Black: Pneumoconiosis or Smokers.

    White: Allergic (BA), Viral infection.

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    Mucoid: Bronchial Asthma.

    Mucopurulent: Bronchitis, Pneumonia.

    Purulent: Suppurative lung diseases e.g. Lungabscess, Bronchiectasis.

    Frothy Blood-tinged: Pulmonary Oedema.

    Comment on Expectoration

    Aspect (Consistency):

    Mostly in the morning e.g. Bronchiectasis.

    Time of Occurrence:

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    Haemoptysis

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    It is Coughing ofBlood originating from Below

    the Vocal Cords.

    Haemoptysis

    Definition:

    Bleeding originating from Above the VocalCords is considered False Haemoptysis.

    Haemoptysis may range from Blood-streakedSputum to Frank Haemoptysis.

    C f H t i

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    Traumatic: e.g. Foreign Body.

    Causes of Haemoptysis

    Respiratory Causes:

    Inflammatory:

    - Specific: e.g. TB

    - Non-Specific: e.g. Bronchitis, Pneumonia,Bronchiectasis, Lung Abscess

    Neoplastic:

    - Benign: e.g. Bronchial Adenoma.- Malignant: e.g. Bronchogenic Carcinoma.

    Vascular:

    - Pulmonary Embolism.

    - Pulmonary Oedema.

    C f H t i

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    Mitral Stenosis. Left Heart Failure.

    Aortic Aneurysm weeping into a bronchus.

    Causes of Haemoptysis

    Cardio-Vascular Causes:

    Haemophilia. Leukemia.

    General Causes: Haemorrhagic Diseases

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    D.D. between Haemoptysis & Haematemesis

    HaematemesisHaemoptysis

    Vomiting of BloodCoughing of BloodDefinition

    Dark Brown

    (Acid Haematin)

    Bright Red

    (Oxyhaemoglobin)Color

    Mixed with Food ParticlesFrothyNature

    AcidicAlkalineReaction

    MelenaBlood-tinged SputumAfter the

    attack

    H t i

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    Haemoptysis

    Is there is any blood in the sputum?

    Is it fresh or altered?

    How often has it been seen?

    For how long?

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    Wheezing

    Wh i

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    Wheezing

    Do you hear any noises coming from

    the chest?

    Sometimes wheezing is noticed by

    others (especially by a partner at

    night when asthma is worse).

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    Questions ?