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Presentation Presentation PryMarke, LLC (USA) MRI Project: Gebze June, 2015

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Page 1: MRI Project

PresentationPresentation

PryMarke, LLC (USA)MRI Project: Gebze

June, 2015

Page 2: MRI Project

MRI Global MRI Global MarketplaceMarketplace

Global MRI market currently US$5.8 billion (2015), and will grow to Global MRI market currently US$5.8 billion (2015), and will grow to

US$6.8 billion (2020). (Magnetica, 2014; Markets and Markets, 2015)US$6.8 billion (2020). (Magnetica, 2014; Markets and Markets, 2015)

Major manufacturers: GE (USA), Philips (Netherlands), Siemens Major manufacturers: GE (USA), Philips (Netherlands), Siemens

(Germany), Hitatchi (Japan), Toshiba (Japan)(Germany), Hitatchi (Japan), Toshiba (Japan)

Market segmented into the following areas: Brain, Head, Neck (29%); Spine Market segmented into the following areas: Brain, Head, Neck (29%); Spine

(25%); Extremity (24%); Vascular (8%); Pelvic & Abdominal (7%)(25%); Extremity (24%); Vascular (8%); Pelvic & Abdominal (7%)

Categorized into the following field strengths: Low (<0.5T), Mid (0.5-1T), Categorized into the following field strengths: Low (<0.5T), Mid (0.5-1T),

High (1.5T), and Very High (3T)High (1.5T), and Very High (3T)

PryMarke, LLC

Page 3: MRI Project

MRI Marketplace MRI Marketplace (Continued)(Continued)

Major reasons for growth: Rising aging population, awareness of early Major reasons for growth: Rising aging population, awareness of early

diagnosis, technological advancements (superconducting magnets, open diagnosis, technological advancements (superconducting magnets, open

architecture, software applications)architecture, software applications)

Market restrictions include high costs of systems, declining reimbursement Market restrictions include high costs of systems, declining reimbursement

rates for MRI procedures, shortage of helium gas deposits, and trainingrates for MRI procedures, shortage of helium gas deposits, and training

Emerging markets (BRIC and CIVETS) and Asia/Pacific region of Emerging markets (BRIC and CIVETS) and Asia/Pacific region of

particular interest to investors in the MRI marketplace particular interest to investors in the MRI marketplace

PryMarke, LLC

Page 4: MRI Project

Special NotesSpecial Notes

Asia expected to be the fastest growing region through 2020Asia expected to be the fastest growing region through 2020

Niche markets for extremity imaging growing quicklyNiche markets for extremity imaging growing quickly

Arms, hands, wrists, knees, ankles (25% of all scans in USA)Arms, hands, wrists, knees, ankles (25% of all scans in USA)

Current total number of systems estimated at 3,500 worldwideCurrent total number of systems estimated at 3,500 worldwide

US, European, and Japanese markets represent 80% of that totalUS, European, and Japanese markets represent 80% of that total

China and India expected to enter marketplace soonChina and India expected to enter marketplace soon

Extremity scans break-even at 4-5 patients per day compared to 20-23 Extremity scans break-even at 4-5 patients per day compared to 20-23

patients per day for very high-field whole body scanspatients per day for very high-field whole body scansPryMarke, LLC

Page 5: MRI Project

Special Notes Special Notes (Continued)(Continued)

Sales of very high field whole body systems have grown rapidly to almost Sales of very high field whole body systems have grown rapidly to almost

500 units per year500 units per year

Average sales price for “gold standard” high field scanner US$1.1 million Average sales price for “gold standard” high field scanner US$1.1 million

and US$2.3 million for very high field systemand US$2.3 million for very high field system

Superconducting magnet system in MRI scanner is 30% of total system costSuperconducting magnet system in MRI scanner is 30% of total system cost

Strong indication that patients and doctors demand high-field scans and will Strong indication that patients and doctors demand high-field scans and will

travel overseas if necessary, thus forcing clincs to upgrade systemstravel overseas if necessary, thus forcing clincs to upgrade systems

Over 13,000 systems recalled in early 2015 by GE and Siemens due to FDA Over 13,000 systems recalled in early 2015 by GE and Siemens due to FDA

protocol; magnetic interference largest problem followed by trainingprotocol; magnetic interference largest problem followed by training PryMarke, LLC

Page 6: MRI Project

Superconducting Magnet Superconducting Magnet ProducersProducers

GE, Siemens, and Philips (“Big 3”) have own in-house production but have legacy GE, Siemens, and Philips (“Big 3”) have own in-house production but have legacy

factories that are expensive to run and cannot change set-ups quicklyfactories that are expensive to run and cannot change set-ups quickly

Hitachi does not have capability to design and manufactureHitachi does not have capability to design and manufacture

Toshiba does not have capability to manufacture whole body magnetsToshiba does not have capability to manufacture whole body magnets

““Big 3” have limited capacity to produce turnkey solutionsBig 3” have limited capacity to produce turnkey solutions

Mitsubishi is the only independent major magnet manufacturer but does not produce Mitsubishi is the only independent major magnet manufacturer but does not produce

tailor-made solutions and has current-driven cost fluctuation challengestailor-made solutions and has current-driven cost fluctuation challenges

Other superconducting manufacturers focus on non-MRI magnets (e.g., Magnex in Other superconducting manufacturers focus on non-MRI magnets (e.g., Magnex in

the UK and Bruker in Germanythe UK and Bruker in Germany

No truly independent magnet manufacturersNo truly independent magnet manufacturers PryMarke, LLC

Page 7: MRI Project

MRI Research MRI Research UniversitiesUniversities

PryMarke, LLC

Stanford University (California, USA)Stanford University (California, USA)

Emory University (Atlanta, Georgia, USA)Emory University (Atlanta, Georgia, USA)

Columbia University (New York, USA)Columbia University (New York, USA)

Yale University (Connecticut, USA)Yale University (Connecticut, USA)

University of Michigan (Michigan, USA)University of Michigan (Michigan, USA)

Cornell University (New York, USA)Cornell University (New York, USA)

Brown University (Rhode Island, USA)Brown University (Rhode Island, USA)

University of British Columbia (Canada)University of British Columbia (Canada)

Page 8: MRI Project

Major Major SuggestionsSuggestions

Consider Chinese and Indian marketplaces for Consider Chinese and Indian marketplaces for

potential clients as well as partnerspotential clients as well as partners

Investigate MRI and CT scanners for real-time use Investigate MRI and CT scanners for real-time use

during surgeriesduring surgeries

Engage in university-industry collaborationEngage in university-industry collaboration

Target extremity marketplace first followed by Target extremity marketplace first followed by

brain, head, and neck markets as systems are brain, head, and neck markets as systems are

smaller and have faster break-even pointssmaller and have faster break-even points

Conduct further research into financial aspects Conduct further research into financial aspects

such as ROI, sustainability, market frictionssuch as ROI, sustainability, market frictionsPryMarke, LLC

Page 9: MRI Project

ReferencesReferences

Frost and Sullivan (Texas, USA)Frost and Sullivan (Texas, USA)

Global Industry Analysts (Maryland, USA)Global Industry Analysts (Maryland, USA)

Magnetica (Queensland, Australia)Magnetica (Queensland, Australia)

Markets and Markets, Inc. (Texas, USA)Markets and Markets, Inc. (Texas, USA)

US Consulate General (Istanbul, Turkey)US Consulate General (Istanbul, Turkey)

PryMarke, LLC

Page 10: MRI Project

Thank You!Thank You!

PryMarke, LLC

PryMarke, LLC (USA)

9408 Bellevue Road

Battle Creek, Michigan 49014

+1-810-458-4597 (USA)

+90-534-245-6611 (Turkey)

[email protected]