mosby items and derived items © 2006 by mosby, inc. slide 1 chapter 23 nutritional support in...
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![Page 1: Mosby items and derived items © 2006 by Mosby, Inc. Slide 1 Chapter 23 Nutritional Support in Cancer and AIDS](https://reader036.vdocuments.us/reader036/viewer/2022062515/56649d255503460f949fc1b1/html5/thumbnails/1.jpg)
Mosby items and derived items © 2006 by Mosby, Inc. Slide 1
Chapter 23 Chapter 23 Nutritional Support in Cancer and AIDS
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Mosby items and derived items © 2006 by Mosby, Inc. Slide 2
Chapter 23Chapter 23
Lesson 23.1Lesson 23.1
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Key ConceptsKey Concepts
• Environmental agents, genetic factors, and any weaknesses in the body’s immune system can contribute to the development of cancer.
• The strength of the body’s immune system relates to its overall nutritional status.
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CancerCancer
• Malignant tumor (neoplasm) can express itself in multiple forms
• Tumors identified by primary site of origin and state of growth
• Stages of tumor development depend on growth rate, degree of functional self-control and amount of spread
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Causes of Cancer Cell Causes of Cancer Cell DevelopmentDevelopment
• Underlying cause is the functional loss of cell control over normal cell reproduction due to: Mutations Chemical carcinogens Radiation damage Viruses Epidemiologic factors Stress and dietary factors
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The Body’s Defense SystemThe Body’s Defense System
• Two populations of lymphocytes in immune system: T cells• Derived from thymus cells
• Activate phagocytes that attack antigens B cells• Derived from bursal intestinal cells
• Produce antibodies that attack antigens
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T and B Cell DevelopmentT and B Cell Development
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Nutrition and ImmunityNutrition and Immunity
• Inadequate nutrition weakens the immune system
• Causes atrophy of tissues in GI structures
• Antibodies are proteins
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Nutrition and HealingNutrition and Healing
• Body tissue strength depends on ability to build and rebuild, which requires optimal nutrition intake
• Protein and key vitamins and minerals, as well as nonprotein energy sources, must be constantly supplied by the diet
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Chapter 23Chapter 23
Lesson 23.2Lesson 23.2
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Key ConceptsKey Concepts
• Nutritional problems affect the nature of the disease process and the medical treatment methods in patients with cancer or AIDS.
• The strength of the body’s immune system relates to its overall nutritional status.
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SurgerySurgery
• All surgery requires nutritional support for the healing process
• General condition of cancer patients is often weakened by the disease process
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Radiation TherapyRadiation Therapy
• Involves high-energy x-rays targeted on the cancer site
• Often kills surrounding healthy cells as well as cancerous cells
• Nutritional problems driven by site and intensity of radiation treatment
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ChemotherapyChemotherapy
• Highly-toxic drugs administered via the blood stream to kill cancer cells
• Use of monoamine oxidase inhibitors (pretreatment antidepressant drugs) requires tyramine-restricted diet
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Systemic Effects of CancerSystemic Effects of Cancer
• Several systemic effects cause continuing weight loss Anorexia, loss of appetite Increased metabolism Negative nitrogen balance
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CachexiaCachexia
• Extreme weight loss and weakness caused by inability to ingest or use nutrients
• Body feeds off its own tissue protein
• Experienced by half of all cancer patients
• Aggressive nutrition therapy is necessary
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Objectives of Nutrition Objectives of Nutrition TherapyTherapy
• Prevention of catabolism Meet increased metabolic demands
• Relief of symptoms
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Principles of Nutritional CarePrinciples of Nutritional Care
• Nutrition assessment Determine and monitor nutritional status Body measurements, calculations of body
composition, laboratory tests, physical examination, clinical observation, dietary analysis
• Personal care plan Daily plan for nutrition therapy incorporated
into nursing care plan
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Nutritional NeedsNutritional Needs
• Energy
• Protein
• Vitamins and minerals
• Adequate fluid intake
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Enteral: Oral DietEnteral: Oral Diet
• Oral diet with supplementation is optimal when tolerated
• Food plan must include adjustments in food texture and temperature, food choices, and tolerances
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Tips for Controlling Nausea Tips for Controlling Nausea and Vomitingand Vomiting
• Try smaller, more frequent meals.
• Eat more when feeling better.
• Eat drier foods with fluids in between.
• Try cold foods, saltier foods.
• Avoid fatty or overly sweet foods.
• Do not recline immediately after eating.
• Replace fluids and electrolytes.
• Use foods with pleasant aromas.
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Tips for Increasing Energy Tips for Increasing Energy and Protein Intakeand Protein Intake
• Add high-calorie condiments, sauces, dressings
• Add extra ingredients during food preparation
• Drink commercial food supplements
• Avoid low-calorie foods and beverages
• Have a meal or snack every 1-2 hours
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Enteral: Tube FeedingEnteral: Tube Feeding
• When GI tract can be used but patient is unable to eat
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Parenteral FeedingParenteral Feeding
• When GI tract cannot be used
• Peripheral vein feeding (for brief time period)
• Central vein feeding (for extended time period)
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PreventionPrevention
• American Cancer Society Eat a variety of healthful foods Adopt a physically active lifestyle Maintain a healthful weight Limit alcohol consumption
• U.S. Food and Drug Administration Low-fat diets rich in grain products, fruits, and
vegetables may reduce the risk of some cancers
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Chapter 23Chapter 23
Lesson 23.3Lesson 23.3
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Key ConceptsKey Concepts
• The progressive effect of the human immunodeficiency virus (HIV) through its three stages of white T-cell destruction requires aggressive nutrition therapy.
• Nutritional problems affect the nature of the disease process and the medical treatment methods in patients with cancer or AIDS.
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Human Immunodeficiency Human Immunodeficiency VirusVirus
• Virus causes immune system suppression
• Created a widespread epidemic
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Stages of Disease Stages of Disease ProgressionProgression
• Stage 1: Primary HIV infection Flu-like symptoms 4-8 weeks after initial
exposure
• Stage 2: AIDS-related complex Infectious illnesses invade the body
• Stage 3: Final stages of AIDS Rapidly-declining T-helper lymphocyte counts
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Common MicroorganismsCommon MicroorganismsCausing ComplicationsCausing Complications
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Goals of Medical ManagementGoals of Medical Management
• Delay progression of the infection and improve the immune system
• Prevent opportunistic illnesses
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Toxic Effects of Drug TherapyToxic Effects of Drug Therapy
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FDA-Approved Antiretroviral FDA-Approved Antiretroviral DrugsDrugs
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Severe Malnutrition, Weight Severe Malnutrition, Weight LossLoss
• Decreased appetite, insufficient energy intake in addition to elevated resting energy expenditure
• Major weight loss, eventual cachexia
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Causes of Body WastingCauses of Body Wasting
• Inadequate food intake
• Malabsorption of nutrients
• Disordered metabolism
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Nutrition AssessmentNutrition Assessment
• Anthropometry
• Biochemical tests
• Clinical observations
• Diet observations
• Environmental, behavioral and psychological assessment
• Financial assessment
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Principles of Nutrition Principles of Nutrition CounselingCounseling
• Motivation for dietary changes
• Rationale for nutrition support
• Provider-patient agreement on plan
• Development of manageable steps for change
• Development of personal food management skills
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Planning Nutrition CarePlanning Nutrition Care