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Enjoy the best combination of product quality and value when you select BD Biosciences multicolor flow cytometry reagents. For over 25 years BD Pharmingen™ brand reagents have been developed and manufactured with strict controls and high standards to ensure high lot-to-lot consistency and performance on BD flow cytometers. Our ever expanding portfolio is the most cited on the market and includes rare combinations of antibodies and fluorochromes that let you use BD reagents across your entire multicolor panel. Recent portfolio additions include the innovative new BD Horizon™ Brilliant Violet™ dyes whichare 5–10X brighter than conventional dyes to assist the resolution of rare or dim populations. All BD Biosciences reagents are backed with expert technical support and a variety of tools and information to enable you get the most from your multicolor panels and help speed your research. Now, new pricing makes high quality and reliability more affordable. You may also be eligible for a more attractive institutional discount—contact your BD Biosciences sales representative to find out more at bdbiosciences.com/reagents Lower pricing means you don’t have to sacrifice quality. For Research Use Only. Not for use in diagnostic or therapeutic procedures. BD, BD Logo and all other trademarks are property of Becton, Dickinson and Company. © 2013 BD 23-14867-00 BD Biosciences 2350 Qume Drive San Jose, CA 95131 bdbiosciences.com More affordable BD Research Reagents Lower pricing on over one thousand high-quality products.

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Page 1: More affordable BD Research Reagents - Sciencescience.sciencemag.org/content/sci/339/6125/local/advertising.pdfthe busiest of cell biology or screening laboratories, the Cytomat 10

Enjoy the best combination of product qualityand value when you select BD Biosciencesmulticolor flow cytometry reagents.

For over 25 years BD Pharmingen™ brandreagents have been developed and manufacturedwith strict controls and high standards to ensurehigh lot-to-lot consistency and performance onBD flow cytometers.

Our ever expanding portfolio is the most citedon the market and includes rare combinationsof antibodies and fluorochromes that let you useBD reagents across your entire multicolor panel.Recent portfolio additions include the innovative

new BD Horizon™ Brilliant Violet™ dyeswhichare 5–10X brighter than conventional dyesto assist the resolution of rare or dim populations.

All BD Biosciences reagents are backed withexpert technical support and a variety of toolsand information to enable you get the mostfrom your multicolor panels and help speed yourresearch. Now, new pricing makes high qualityand reliability more affordable.

You may also be eligible for a moreattractive institutional discount—contact yourBD Biosciences sales representative to findout more at bdbiosciences.com/reagents

Lower pricing means you don’thave to sacrifice quality.

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

BD, BD Logo and all other trademarks are property of Becton, Dickinson and Company. © 2013 BD

23-14867-00

BD Biosciences2350 Qume DriveSan Jose, CA 95131bdbiosciences.com

More affordable BD Research ReagentsLower pricing on over one thousand high-quality products.

Page 2: More affordable BD Research Reagents - Sciencescience.sciencemag.org/content/sci/339/6125/local/advertising.pdfthe busiest of cell biology or screening laboratories, the Cytomat 10
Page 3: More affordable BD Research Reagents - Sciencescience.sciencemag.org/content/sci/339/6125/local/advertising.pdfthe busiest of cell biology or screening laboratories, the Cytomat 10

Mandarin Ducks (Aix galericulata) are frequently featured

in Chinese art and are regarded as a symbol of fidelity.

Fidelity atits finest.Q5® High-Fidelity

DNA PolymeraseQ5 High-Fidelity DNA Polymerase sets a new

standard for both fidelity and performance. With

the highest fidelity amplification available (>100X

higher than Taq), Q5 DNA Polymerase results

in ultra-low error rates. Its unique buffer system

provides superior performance for a broad range

of amplicons, regardless of GC content. Available

in master mix and hot start formulations, Q5 DNA

Polymerase represents the finest in fidelity.

For more information, visit

www.Q5PCR.com

Robust amplification even with high GC amplicons

Amplification of two human genomic amplicons of mid to high GC content.All reactions were conducted using 30 cycles of amplification and visualizedby microfluidic LabChip® analysis. All polymerases were cycled according tomanufacturer’s recommendations. For the 78% GC amplicon, GC Buffers orenhancers were used when supplied with the polymerase.

A = Q5® High-Fidelity DNA Polymerase (NEB)B = Phusion® High-Fidelity DNA Polymerase (NEB)C = KOD DNA Polymerase (EMD)D = PfuUltra™ High-Fidelity DNA Polymerase (Agilent)

60% GC 78% GC

490029001900

1100

700

500

300

bp L A B C D A B C D

PHUSION® is a registered trademark and property of Thermo Fisher Scientific.

Phusion® DNA Polymerase was developed by Finnzymes Oy, now a part of Thermo Fisher Scientific.

PFUULTRA™ is a trademark of Agilent Technologies, Inc.

LABCHIP® is a registered trademark of Caliper Life Sciences, part of Perkin Elmer, Inc.

NEBNEXT® and Q5® are registered trademarks of New England Biolabs, Inc.

ALSO AVAILABLE: Optimized NEBNext® formulation

for next generation sequencing library amplification

Page 4: More affordable BD Research Reagents - Sciencescience.sciencemag.org/content/sci/339/6125/local/advertising.pdfthe busiest of cell biology or screening laboratories, the Cytomat 10

Stem Cell Lawsuit Finally Over.

Russian Team Retrieves First

Sample from Lake Vostok. Surprise

Choices Mark New Leadership on

U.S. House Science Panel. India

Unveils Ambitious Science Policy.

Now, more than ever, developments in the lab are directly connected to decisions made in

the halls of government.

ScienceInsider, the policy blog from the journal Science, is your source for news from the

intersection of science and policy. From budget debates in the United States Congress, to

climate change agreements at the United Nations, ScienceInsider covers the issues that have

an impact on your work, your field, and your world.

Keep up to date and keep informed. Go inside the issues at www.ScienceInsider.org

Breaking news and analysis from the world of science policy

Page 5: More affordable BD Research Reagents - Sciencescience.sciencemag.org/content/sci/339/6125/local/advertising.pdfthe busiest of cell biology or screening laboratories, the Cytomat 10

A UNIQUE OPPORTUNITY FOR SCIENTISTS

FROM AROUND THEWORLD:

LIFE SCIENCES AT THEWISSENSCHAFTSKOLLEG

For 30 years the Wissenschaftskolleg zu Berlin (Institute for Advanced Study) has served as anintellectual resort for internationally recognised researchers as well as promising younger scholars, in

a variety of disciplines in the natural sciences,social sciences, humanities, literature, musicetc., to pursue their pet projects for a year,unhindered by the normal teaching andadministrative duties of their home institutions.In a typical year theKolleg consists of some 40Fellows from different countries and cultures,speaking different languages and pursuingspecialized intellectual tasks in their chosendisciplines, but at the same time presentingtheir work and their ideas to each other duringweekly colloquia and daily meals and otherinformal occasions. In doing so they bene�t

from critique provided by an outstanding community of scholars coming from diverse intellectualdisciplines and academic traditions. The local environment of the Grunewald forest and indeed therapidly changing city of Berlin make no small contribution to make the Fellowsí year at the Kolleg amemorable one.

Over the years, R¸digerWehner, Raghavendra Gadagkar and Paul Schmid-Hempel have been workingwith theWissenschaftskolleg to make a special effort to bring into this milieu, scholars from the broadarea of life sciences, giving outstanding biologists and biomedical researchers the opportunity to spenda year away from their laboratories, rethinking the foundations of their disciplines, writing syntheticreviews and monographs or simply to chart a new course for their future research.

Distinguished scientists including JanisAntonovics, Robert Boyd,Ansgar B¸schges, Tecumseh Fitch,Steven Frank, Yoh Iwasa, Alex Kacelnik, Axel Meyer, Cynthia Moss, Robert Page, Andrew Read,MandyamSrinivasan, Luc Steels, and Eˆrs Szathm·ry have availed of this opportunity.Many in�uentialbooks, e.g. The Wisdom of the Hive (Thomas Seeley, Harvard, 1995), Social Evolution in Ants (A.Bourke and Nigel Franks, Princeton, 1995), Foundations of Social Evolution (S. Frank, Princeton,1998), Self-Organization in Biological Systems (Scott Camazine et al, Princeton, 2001), The Evolutionof Social Wasps (James Hunt, Oxford, 2007), Deceit and Self-Deception (Robert Trivers, 2011), werewholly or partly written at the Wissenschaftskolleg.

TheWissenschaftskolleg provides an excellent library service, arranges accommodation and helps withpractical matters connected with relocation, including schooling of children where needed. Fellows areinvited singly or in small focus groups.While the normal fellowship is for 10 months (mid-Septemberto mid-July), in exceptional cases younger scholars (post-doc, early career) who cannot be away fromtheir institutions for a whole year, are offered the opportunity to spend 3months at the Kolleg. Fellowswho are unable to obtain paid leave of absence from their institutions are either offered a stipend orthe Kolleg may pay their institutions to hire a replacement for the year.

If you are interested in such an opportunity you �nd more information at (http://www.wiko-berlin.de)andmaywrite to Permanent Fellows Paul Schmid-Hempel ([email protected]), Raghavendra Gadagkar([email protected]), or to Katharina Biegger ([email protected]) of the Kolleg admin-istration.

WISSENSCHAFTSKOLLEG ZU BERLINWALLOTSTRASSE 19 D-14193 BERLIN

Page 6: More affordable BD Research Reagents - Sciencescience.sciencemag.org/content/sci/339/6125/local/advertising.pdfthe busiest of cell biology or screening laboratories, the Cytomat 10

Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are

featured in this space. Emphasis is given to purpose, chief characteristics, and availability of products and materials. Endorsement by Science or AAAS of any products or

materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

1339

Produced by the Science/AAAS Custom Publishing Office New Products: General Lab Equipment

Life Science Technologies

Electronically submit your new product description or product literature information! Go to www.sciencemag.org/products/newproducts.dtl for more information.

www.sciencemag.org/products SCIENCE VOL 339 15 MARCH 2013

LIGHT-SENSITIVE SAMPLE PROTECTIONTo protect light-sensitive samples, a selection of high-quality black mi-croplates and seals are offered that eliminate sample degradation, evenover long storage periods. Manufactured from ultrapure grade poly-propylene, Porvair black microplates are resistant to a wide range ofsolvents and have near-zero leachates, ensuring long-term sample in-tegrity.The black plates are supplied RNase/DNase free meaning theycan be used with even the most sensitive biological samples. Availablein a choice of 96-well formats, these plates are precisely manufacturedto applicable ANSI/SLAS dimensions ensuring complete compatibilitywith almost all readers and automated equipment.To prevent evapora-tion and hydration of DMSO solutions and to completely eliminate lightfrom samples, a choice of black light-absorbing sealing films, which canbe applied to the top of the black plates, are also available.Porvair SciencesFor info: +44-(0)-1372-824290 www.porvair-sciences.com

TUBE DECAPPERThe Univo Electric Decapper DC480 enables researchers tasked withopening multiple sample storage tubes to achieve significant productiv-ity gains.The Univo Electric Decapper DC480 is not only compatiblewith all Micronic tubes (up to 1.40 mL) but also with tubes and caps ofother brands.Through an improved user interface the operator is ableto select any rack to decap, without using different adapters for differ-ent tube sizes or brands. Easy to install and operate, the compact UnivoElectric Decapper DC480 removes and disposes of the push caps froma full 96-tube storage rack in eight seconds. Operation is safe and userfriendly: simply place a rack of capped tubes onto the access tray, pushthe start button, and the Univo Electric Decapper DC480 will gentlyremove all the caps in one action. The integrated cap disposal deviceensures that caps cannot be reused.The decapper can be used as a stand-alone instrument or be simply integrated into a fully automated labora-tory environment.MicronicFor info: +31-320-277070 www.micronic.com

AUTOMATED INCUBATORThe new Cytomat 10 is a fully automated incubator and storage modulefor high-capacity cell growth and assay incubation. Designed to fit intothe busiest of cell biology or screening laboratories, the Cytomat 10offers superior environmental control and can be seamlessly integratedwith existing automated assay hardware.The Cytomat 10 provides a fastplate access time of less than 10 seconds.Additionally, multiple transferpositions and an under-bench version allow flexible incubator place-ment within the laboratory.As the first generation of automated incuba-tor with a fully validated thermal decontamination system, the Cytomat10 is designed to significantly decrease the risk of contamination andreduce assay variability. An efficient thermal disinfection method prac-tically eliminates germs and spore suspensions, even in areas that aredifficult to reach via manual cleaning.Thermo Fisher ScientificFor info: 905-332-2000 www.thermoscientific.com/automate

MICROPIPETTESA new range of micropipettes are designed to provide optimal easeof use and assure a high level of user comfort during operation, mini-mizing the risk of repetitive strain injury. Integral to the design of thevariable volume pipette is an innovative soft grip and safety device onthe thumb-controlled plunger.This feature prevents accidental volumechanges during use, facilitating maximum precision and accuracy. Theuniversal two-step plunger allows reverse pipette techniques to beperformed and enables last drop dispensing.The micropipettes may besafely autoclaved at 120°C and 1.05 bar/15 psi for 15 minutes. Main-tenance and adjustment are simple procedures as the user can readilyrecalibrate the micropipette with the adjustment tool supplied. Thereare eight variable models covering volume ranges from 0.1–5,000 µL.A further 14 fixed volume models compliment the range covering5–10,000 µL and four or six position bench racks are available for easystorage.Medline ScientificFor info: +44-(0)-1865-400321 www.medlinescientific.com

HANDHELD PIPETTING SYSTEMDesigned to enable labs to process samples simply and productively, the VIAFLO 384 is a newhandheld 384-channel electronic pipette that enables fast, precise, and easy transfer of 384 samplessimultaneously. Uniquely, the VIAFLO 384 offers all the benefits of increased sample throughput aswell as lower sample and reagent use without the expense of having to invest in a robotic liquidhandling system.The compactVIAFLO 384 comes with a choice of two 384-channel pipetting heads,which cover the volume ranges of 0.5–12.5 µL and 5–125 µL.The new system is fully compatible withVIAFLO 96-channel pipetting heads enabling easy switching between 96-channel and 384-channelpipetting using the same unit.TheVIAFLO 384 features the company’s popularTouchWheel pipetteuser interface for simple and fast programming of a wide range of pipetting modes including repeatdispense, serial dilute, and mixing routines.Integra BiosciencesFor info: +41-(0)-81-286-95-30 www.integra-biosciences.com

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Faculty Positions at ShanghaiTech University

ShanghaiTech University is a newly established research university located at Zhang-Jiang High-Tech Park in Pudong, Shanghai, China. Currently, it has fourschools and several advanced research institutes: School of Physical Science and Technology, School of Life Science and Technology, School of InformationScience and Technology and School of Entrepreneurship and Management with expected enrollment of 4,000 graduate and 2,000 undergraduate students.The new University is jointly supported by Chinese Academy of Sciences and Shanghai Municipal Government. The vision of ShanghaiTech is to be aglobally recognized top research university for its size and profound integration of education, research and innovation by creating a dynamic people centeredhub where innovative research, education, and community service meet to provide a multi-disciplinary approach to learning and to solving problems facingsociety. As a new university, we expect to set up new policies to support an academic environment for best practices of research, teaching and learning. TheUniversity will build state of art research and teaching facilities including large research instruments, modern library and classrooms. Our faculty will havethe access to the research facilities and resources of Chinese Academy of Sciences. Shared governance will be a part of the campus culture.

We are currently seeking applicants for multiple tenure-track and tenured positions at all ranks.

Initial Research Support Package:University will provide internationally competitive start-up fund plus support of ResearchAssociate and Post-Doctoralfellows. Laboratory space will be provided matching the research needs.

Compensation and Benefts: Salary is competitive and commensurate with experience and academic accomplishments. ShanghaiTech also offers acomprehensive beneft package including housing benefts.

1. School of Physical Science and Technology (SPST)

SPST is established to encourage interdisciplinary research particularlyfocused on Materials, Environment and Energy. The School is expected tohave about 100 regular tenured and tenure-track faculty, 1,200 graduate and750 undergraduate students.

Qualifcations: Successful applicants should have a doctoral degree inPhysical Science and Engineering as well as postdoctoral experience forjunior level position. They will be expected to establish an independent,internationally recognized research program, to supervise students and toteach two courses a year. The senior position applicant is expected be leadingscientist in his/her research disciplinary.We particularly welcome those withresearch interests related to Energy, Materials and Environment Science andEngineering to apply.

2. School of Information Science and Technology (SIST)

SIST seeks faculty candidates in all cutting edge areas of informationscience and technology, with special focus on: advanced futuristic computerarchitecture and technology, nano-scale electronics, ultra-high speed andlow power circuits, intelligent multimedia and integrated signal processingsystems, next-generation computer systems, computational foundations,big data, data mining, visualization, computer vision, bio-computing, smartenergy devices and systems, highly-scalable andmulti-service heterogeneousnetworking, as well as various inter-disciplinary areas involving thefoundation and applications of information science and technology.

Qualifications: Candidates must demonstrate: A strong interest inundergraduate and graduate education; Well-developed research plans anddemonstrated strength; Ph.D. (Electrical Engineering, Computer Engineering,Computer Science, or closely related feld); A minimum relevant researchexperience of 4 years.

3. School of Life Science and Technology (SLST)

SLST seeks early career scientists in these fve research areas: Protein scienceand biotechnology; Stem cell research and regenerative medicine; Systemsbiology and translational medicine; Physical biology andmolecular imaging;Chemical biology and innovative pharmacology.

Qualifcations: The successful candidates should have an exceptional trackrecord of research in life sciences or a closely related discipline within thelast fve years. Besides maintaining an active research program, the recruitedcandidates will also be expected to contribute to the educational missions ofundergraduate and graduate programs within SLST.

4. School of Entrepreneurship and Management (SEM)

SEM provides students with practical knowledge in strategic emergingindustries where there is a high demand for commercialization of innovationthat advances China's economic development. SEM programs focus on theapplied felds of technology innovation management, entrepreneurship andMSE management, as well as venture capital management. SEM offersadvanced studies through MBA, EMBA, and EDP programs.

Qualifcations:An applicant should possess a doctoral degree in professionalstudies such as Economics, Finance, or Management. Industry experience ispreferred but not necessary. Faculty responsibilities include teaching MBAor EMBA students and conducting applied research often working withcompanies. SEM especially welcomes applicants with interests related toInnovation, Entrepreneurship, and Venture Capital.

5. The iHuman Institute

The iHuman Institute is established to encourage interdisciplinary researchfocused on human cell signaling combining chemistry, biology, imaging,and structural biology. Integration of academic basic sciences and appliedsciences with industry will be integrated together providing all researcherswith unique scientifc opportunities.

Qualifcations: Successful applicants should have a doctoral degree inPhysical or Life Sciences as well as postdoctoral experience for juniorlevel position. Applicants will be expected to establish an independent,internationally recognized research program and supervise students. Thesenior position applicants are expected be leading scientists in his/her researchdisciplinary. We particularly welcome those with research interests relatedto chemical biology and bioinformatics to apply.

6. Shanghai Institute for Advanced Immunochemical Studies (SIAIS)

SIAIS focuses on elucidating the most fundamental problems in life scienceresearch, particularly in immunochemistry.We are seeking highly motivatedand outstanding candidates with strong interests in antibody design andengineering, antibody assay method and platform technology, antibodytherapeutics, structural biochemistry, and translational medical research.

Qualifcations: QualiQed candidates should possess a doctoral degreein physical or life science with successful track records in academia andpharmaceutical industry. SIAIS particularly welcomes those with researchinterests that emphasize innovation and transformation.

Application Procedure: Submit a cover letter, a 2-3 page statement of research interests, a CV and the names and addresses of three individuals who canserve as references to the mail addresses given below:

School of Physical Science and Technology [email protected]

School of Information Science and Technology [email protected]

School of Life Science and Technology [email protected]

School of Entrepreneurship and Management [email protected]

The iHuman Institute [email protected]

Shanghai Institute for Advanced Immunochemical Studies [email protected]

ShanghaiTech University, Building 2, 319 Yueyang Road, Shanghai 200031, China

Review of applications will start immediately and will continue until positions are Rlled.

For more information, please visit our website: www.shanghaitech.edu.cn

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Page 8: More affordable BD Research Reagents - Sciencescience.sciencemag.org/content/sci/339/6125/local/advertising.pdfthe busiest of cell biology or screening laboratories, the Cytomat 10

Cancer Biology

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