MONTHLY INTELLIGENCE | UPCOMING EVENTS

MONTHLY HEALTHCARE NEWSLETTER - OCTOBER 2019A GLOBAL LEADER IN STRATEGIC HEALTHCARE COMMUNICATIONSLondon | New York | Boston | San Francisco

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MONTHLY INTELLIGENCE

Following a successful fundraise earlier this year, Quanta is preparing to launch its game-changing personal haemodialysis system, SC+, in the UK...

Why is the launch of your new dialysis system so exciting?Our mission is to improve the lives of dialysis patients through innovation. We want to do this by empowering patients to take control of their lives by providing greater flexibility around where, when and how they manage and receive their life-sustaining dialysis therapy.

There has been a distinct lack of innovation in the field of dialysis

and current treatment options just aren’t good enough. There

are, however, clear ways we can improve patient's experience of dialysis, such as shifting them to

home treatment.

Our haemodialysis system allows patients to do this and start their journey towards self-care, giving them a better quality of life and helping them get the best possible clinical outcomes. That mission, and that need, is tremendously motivating for me, and everyone at Quanta.

Where would you like to see the Company in five years?In five years, we want to be the standard of care for home haemodialysis and self-care in Europe and North America. By that point, we should also be starting to introduce our solution into new settings, new indications and in other parts of the world.

CEO LIFE: A Q&A WITH JOHN E. MILADCEO OF QUANTA DIALYSIS TECHNOLOGIES

Who is your biggest inspiration as a CEO?In terms of dreaming to do the impossible, I find Elon Musk inspiring – he is looking to completely disrupt big industries through bold innovation. In our own way, that’s what we at Quanta are trying to do in dialysis, by changing the whole delivery model through technology innovation.

In business, I find Warren Buffet very inspiring – on the one-hand he has been tremendously successful—and clearly has a lot of acumen and knows how to cut sharp deals—but on the other hand he conducts himself with integrity. I very much respect and admire his ability to combine enormous success with being an extraordinarily decent person.

What piece of advice would you give to someone starting their career today? Focus on building something you believe in. If you get this right, then success will follow.Also, be prepared for continuous learning and development. There is no static set of skills that is going to be suitable for your whole career.

What do you do to relax?Beyond just spending time with family, I love cooking – the whole process of it. I’m a scratch cook and enjoy the blend of art and science, the satisfaction of developing my skills and techniques, and the opportunity to get into the zone and focus my mind on a completely different set of problems. Most importantly, this is something enjoyable that I can share with my family.

How do you find working in Britain as an American?The longer I live here the more I agree with Churchill’s statement that we are two nations divided by a common language. The cultures are deceptively close but profoundly different.

MEDIA MOVES – The Daily Telegraph’s Julia Bradshaw is now on maternity leave. Hannah Uttley is now covering the pharma sector

– Tom Howard has joined The Times as market reporter – Kaya Burgess is covering The Times Health Correspondent Kat Lay's maternity leave – Ayisha Sharma has joined BioPharm Insight as healthcare reporter

ANALYST MOVES – Ross Blair has joined RX Securities from Bryan Garnier

If you would like to receive our Monday Healthcare Bulletin, which summarises all healthcare business news from the weekend, please contact: admincsc@consilium-comms.com

– 4BIO Capital appointed Philippe Fauchet, OBE as a Venture Partner based in Japan

– Ergomed plc announced that Dr Jan Petracek has stepped down as COO and Board Director, as well as CEO of PrimeVigilance. Jonathan West, currently CBO of PrimeVigilance, will take on the role of President of PrimeVigilance. Peter George also stepped down from the Board.

– iTeos Therapeutics SA appointed Gordon Freeman, William Hahn, Ben Stanger and Matt Vander Heiden to its Scientific Advisory Board

– MedEye appointed Jort Kooistra as CEO – QuantuMDx Group appointed Neil Butler as a Non-Executive Director

– Vectura announced that Dr Susan Foden stepped down from the Board and her role as Senior Independent Non-Executive Director

– Sensyne Health appointed Charles Swingland as Chairman, although owing to a period of illness, Annalisa Jenkins is currently interim Chair

– Akcea announced that CEO Paula Soteropoulos, CBO Sarah Boyce and COO Jeff Goldberg have stepped down and the appointment of Damien McDevitt as interim CEO

– Akouos appointed Gregory Robinson as CSO, and co-founder Michael McKenna has taken on the full-time CMO role

– Alexion announced that Aradhana Sarin, currently the Chief Strategy and Business Officer will succeed Paul Clancy as CFO who will be departing later this year

– Amnicell appointed Helen Ljungdahl Round as CEO

– Azitra appointed Mark Sampson as CSO – Bayer announced that Non-Executive Directors, Hartmut Klusik and Kemal Malik will depart by the end of the year

– Black Diamond appointed Christopher Roberts as CSO and Tommy Leggett as CFO

– Cala Health appointed Renee Ryan as CEO

– Cerevel appointed Tony Coles as CEO – Click Therapeutics appointed Ross Muken as CFO

– Five Prime Therapeutics announced that CEO Aron Knickerbocker left the company

– Foghorn® Therapeutics appointed Samuel Agresta as CMO and Allan Reine as CFO

– Genfit announced that long-term CEO and co-founder Jean-François Mouney stepped down and that Pascal Prigent will take over

– GlaxoSmithKline's CEO Emma Walmsley joined Microsoft's Board of Directors

– HemoShear appointed Brian Jones as CSO

– Imvax appointed John Furey as its CEO – Locana appointed Kathie Bishop as CSO – Locate Bio appointed John von Benecke as CFO and COO. Rob Quirk, company founder and previously the acting CEO and COO, will be leaving the company

– Midatech Pharma PLC appointed Stephen Stamp as CFO and a Director of the Company with immediate effect, replacing Nick Robins-Cherry

– Oncimmune announced the appointment of Professor Tariq Sethi as CSO, Matthew Luttrell as CCO and Cléa Rosenfeld as Head of Investor Relations

– Oyster Point Pharma announced the appointment of Dan Lochner as CFO and John Snisarenko as CCO

– Passage Bio appointed Gary Romano as CMO

– PureTech Health announced that Joichi 'Joi' Ito has stepped down from the Board of Directors, and current Board member, Chris Viehbacher, will act as interim chair.

– Salix Pharmeceuticals announced that President Mark McKenna will leave the company

– Somatus appointed Jon Kunkle as CFO – Step Pharma appointed Andrew Parker as CEO replacing Geoffroy de Ribains

– Vifor appoined Klaus Henning Jensen as CMO

– Woodford Patient Capital Trust announced that Raymond Abbott has been appointed to the Board as Non-Executive Director and Louise Makin will step down from her role as NED

– Zealand Pharma announced that CSO Andrew Parker, has moved on to be CEO of Step Pharma

THIS MONTH’S MOVERS AND SHAKERS

CONSILIUM STRATEGIC COMMUNICATIONS | CITI | COOLEY | STIFEL | INTRADO

ANNUAL HEALTHCARE CONFERENCE 2019

CONNAUGHT ROOMS WC2B19 NOVEMBER

HIGHLIGHTED FUNDRAISING ACTIVITY FROM SEPTEMBER TO OCTOBER 2019

COMPANY NAME AMOUNT RAISED

TYPE OF FUNDRAISE COUNTRY DATE

PUBLIC COMPANY FINANCINGS

10x Genomics Inc. $390 million IPO US 13-Sept-19

SpringWorks Therapeutics Inc. $162 million IPO US 13-Sept-19

Satsuma Pharmaceuticals Inc. $82.5 million IPO US 14-Sept-19

Acadia Pharmaceuticals $250 million Follow-on US 18-Sept-19

Fate Therapeutics Inc. $150.5 million Follow-on US 18-Sept-19

Translate Bio Inc. $90 million Follow-on US 18-Sept-19

PTC Therapeutics Inc. $100 million Follow-on US 18-Sept-19

Shanghai Henlius Biotech Inc. $409.9 million IPO Hong Kong 19-Sept-19

IGM Biosciences Inc. $175 million IPO US 20-Sept-19

Amryt Pharma plc $60 million Follow-on UK 25-Sept-19

Aprea $75 million IPO US 07-Oct-19

PRIVATE COMPANY FINANCINGS

Aural Analytics Inc. $4.3 million Seed funding US 5-Sept-19

Karuna Labs $3 million Seed funding US 10-Sept-19

Pharvaris B.V. $66 million Series B Netherlands 10-Sept-19

Rhythm AI Ltd. $2.6 million Seed funding UK 10-Sept-19

Genenta Science s.r.l. $14.4million Series C Italy 11-Sept-19

Insilico Medicine Inc. $37 million Series B China 11-Sept-19

OncoCell Mdx Inc. $22.2 million Series B US 11-Sept-19

Platelet BioGenesis Inc. $26 million Series A-1 US 11-Sept-19

SGI-DNA $25 million Series A US 11-Sept-19

Healthy.io Ltd. $60 million Series C Israel 13-Sept-19

Inotrem S.A. $43 million Series B France 13-Sept-19

EdiGene Inc. $11 million Series pre-B2 China 16-Sept-19

CMR Surgical $240 million Series C UK 17-Sept-19

One Drop $40 million Series B US 17-Sept-19

Themis $44.3 million Series D Austria 18-Sept-19

Ginkgo Bioworks Inc. $290 million Series E US 19-Sept-19

Versantis AG $16.1 million Series B Switzerland 19-Sept-19

Curamir Therapeutics Inc. $10 million Series A US 20-Sept-19

Vedanta Biosciences $16.6 million Series C-2 US 23-Sept-19

Amphivena Therapeutics Inc. $62 million Series C US 25-Sept-19

Tacalyx $7.7 million Seed funding Germany 25-Sept-19

Meissa Vaccines Inc. $30 million Series A US 26-Sept-19

T3 Pharmaceuticals AG $12.2 million Second financing Switzerland 26-Sept-19

ZielBio $25 million Series A US 26-Sept-19

Newronika S.p.A. $9.2 million Series A France 28-Sept-19

STipe Therapeutics $21.9 million Series A Denmark 1-Oct-19

Tenaya $92 million Series A US 3-Oct-19Source: BioCentury

CONSILIUM IS DELIGHTED TO SUPPORT THE BIA BIOSCIENCE FORUM 2019Register now: www.bioindustry.org/

CONSILIUM IS PROUD TO BE A MEMBER OF:

INVESTOR CONFERENCE EVENT CALENDAR

2019

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2020

OCTOBER

BIA UK Bioscience Forum, London (17 October)BIO Investor Forum 2019, San Francisco (22-23 October)10th Galien Forum, New York (24 October)

NOVEMBER

FT Global Pharmaceutical and Biotechnology Conference 2019, London (11-12 November)Credit Suisse Annual Healthcare Conference, Scottsdale (11-13 November)BIO-Europe 2019, Hamburg (11-13 November)Bryan Garnier 2019 Healthcare Conference, Paris (12-13 November)LSX DigiHealth Leaders, London (13-14 November)Stifel Nicolaus Weisel Healthcare Conference 2019, New York (13-14 November)Consilium Strategic Communications Annual Healthcare Conference, London (19 November)Inv€$tival Showcase, London (19 November)Jefferies Healthcare Conference, London (20-21 November)Canaccord Genuity Medical Technology and Diagnostics Forum, New York (21 November)

DECEMBER

Berenberg Bank Annual European Conference, Surrey (2-5 December)Piper Jaffray Annual Healthcare Conference, New York (3-5 December)Forbes Healthcare Summit, New York (4-5 December)61st ASH Annual Meeting & Exposition, Orlando (7-10 December)

JANUARY

Sachs 3rd Annual Neuroscience Innovation Forum, San Francisco (12 January)BioTech Showcase, San Francisco (13-15 January)JP Morgan 38th Annual Healthcare Conference, San Francisco (13-16 January)

Needham & Co. Annual Healthcare Conference, San Francisco (14-15 January)

FEBRUARY

6th Annual LSX World Congress, London (4-5 February)ASCO-SITC Clinical Immuno-Oncology Symposium, San Francisco (6-8 February)Annual BIO CEO & Investor Conference, New York, (10-11 February)13th Annual European Life Sciences CEO Forum, Zurich (19-20 February)Leerink Partners Global Healthcare Conference 2020, New York (25-27 February)

MARCH

Raymond James Annual Institutional Investors Conference, Orlando (1 March)Cowen & Co. Annual Health Care Conference, Boston (2-4 March) New York BIO Annual Conference, New York (10 March) BIO Asia International Conference, Tokyo (10-11 March 2020)Barclays Capital Healthcare Conference, Miami (10-12 March)Roth Capital Partners Annual Conference, Orange County (15-17 March)Oppenheimer & Co. Annual Healthcare Conference, New York (17-18 March)BIO-Europe Spring, Vienna (23-26 March)Morgan Stanley European MedTech & Services Conference, London (TBD)Credit Suisse Healthcare One-on-One Conference, London (TBD) ARM Cell & Gene Therapy Investor Day, New York (TBD)KBC Securities Healthcare Conference, Brussels (TBD)

APRILH.C. Wainwright Global Life Sciences Conference, London (6-7 April)Kempen & Co. Life Sciences Conference, Amsterdam (10 April)BioCentury Future Leaders in the Biotech Industry, New York (12 April) ARM Cell & Gene Meeting on the Mediterranean, Barcelona (15-17 April)BioTrinity 2020, London (29 April)

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