A system of,Molecular dynamics synchronised Manipulatorto repair Biomolecules

It’s a dream comes true on Healthcare

Jayakar Johnson Joseph, Johnsons Medicom (P) Ltd.

www.clustermatteruniverse.net

Requires Further

developments

Inadequate Healthcare modalities

To proceed:Molecular repairing

that includes Genomic repairing

Thus proposes: In-depth analysis

on Molecular dynamics & Manipulation techniques

Demerits of existing Healthcare modalities & Proposed solutions

Therapeutic actions and Side effects are defined only by statistical analysis

Metabolic pathways are assigned only by the detection of molecules in specific localities

Therapeutic

Uncertainty

Inconclusive metabolic pathways

Regulatory Proteins

Poly ADP Ribose

Polymerase

Intentions & main objectives

Protein Synthesis

Apoptosis

Targeted molecules in Malignancy

Field of this work and applied field

Thanks to: Institute for System Biology

Field of work:System Biology

Field of Application:

Healthcare

Eigen-rotational Clusters of

String-matter Universe

This system is developed from the paradigm of:

According to this paradigm, a String-matter segment is equivalent to a particle with field.

Thus the notation of incident on eigen-rotation of a string-segment at the observer/detector locality provides

more information than with the expression of incident beam of particles at the observer/detector locality.

Innovation behind this system of instrumentations

This implies a notation of dual wave lengths on wave propagation and describes the evolution of discrete cyclic-times in holarchy.

A generic wave mechanics is defined to resolve the paradoxes on wave particle duality and wave function collapse, in particle scenario.

Intended to Manipulate the molecular

dynamics of the Target-Source

to repair biomolecules

Objectives

To explore and to study Molecular dynamics in Biological

Systems

Therapeutic Application

How this instrumentation differs in therapeutics ?

Classical

Target of application is locality based

Collateral damage is inevitable

MDSM

Target of application is molecule and element based

Collateral damage is minimized

Some Functional Units of the

System1. Targeted Bio-molecular source retainer for NMR

alignment

2. Tracer molecules delivering Unit

3. Multiple Pyramidal Arrays of detectors

4. Tetrahedral-mesh based Morphometric image processing

5. Data mining Unit

6. Knowledge-Based Fuzzy Controller

7. Unit for System tuning and Configuring

8. Virtual molecular dynamics manipulation unit

9. Synchronisation unit

10.

Matter injecting unit

11.

Energy injecting unit

12.

External Data and commands networking Hub

Classification of Instrumentation

In vitro specimen study

In vivo animal testing

Therapeutic Applications

3 levels of

operations

Tracer molecules delivery Unit

Carbon atoms

Ribosemolecules

Delivery Target

Tetrahedral-mesh based Morphometric image processing

• Labelled data from detector arrays

• Data decomposition

• Processing of Tetrahedral-mesh

Knowledge-Based Fuzzy Controller

KB Fuzzy Controller

Manipulation Benchmark

Synchronization

Extracted data

System Tuning

System tuning & Configuring

External Data

System Tuning

KB Fuzzy Controlle

r

Links

Virtual molecular-dynamics Manipulator

Alters

Data from Detector

array

Synchronization with Phase

shift

Anti-phase Synchronizatio

n

In-phase synchronization

Synchronising Unit

Principles used for Synchronization

No Synchrony

Thanks to: Dr. Arkady Pikovsky & Dr. Michael Rosenblum

Synchronising UnitTriad of Synchronisation

Incident at

detection point

Delivery of Matter to event

point

Delivery of Energy to

event point

In external reference

time, t

In

Discrete-tim

e

In Discrete-time

In Discrete-time

Matter injecting unit

Matrix-assisted laser desorption/ionization

(MALDI)

Electrospray ionization (ESI)

Techniques Applied

Individual or in combination

Energy injecting unit

Pulsed Radio Frequency

External Data and commands networking Hub

Installed System User

Other Systems

in the Cloud

Applications : Direct

In vitro Bio-molecular dynamics

study

In vivo Bio-molecular dynamics study in

animals

New therapeutic modality for Humans

Further Applications in Basic Research

Data by this system

Scaling of Eigen-rotational string-

matter segments in Planck scale

Defining new properties for

Chemical elements

Physics

Chemistry

Future updates of MDSM System

Sound waves

Micro-lithotripsy

Ultra Sound tuning of implants

X-ray

On analysi

s

- ray

On analysi

s

Proposed Inclusions

So happy to say…

Thank You