molecular biology, daniela alarcón

SCIENTISTS FIND WAY TO TRAP, KILL MALARIA

PARASITE AND STEM CELL SCIENTISTS LAY TRAP FOR

DISEASE.Daniela Alarcón Bolívar

Medicine students 3rd semester

U.P.B2014

INTRODUCTION

Nowadays the molecular biology is very important as different investigations could understand how different organisms affect humans.

Also through experimentation in rats it has been thought that in the future might find more and better solutions for diseases such as renal failure. All this for very small things but way too important as DNA.

SCIENTISTS FIND WAY TO TRAP, KILL MALARIA

PARASITE

Malaria is a disease caused by the parasite plasmodium falciparum, this parasite is transmitted by the Anopheles mosquito, he infected itches transmitting disease to the people. It can be transmitted in a placental or blood transfusions. Malaria causes about 627,000 deaths in a year in the tropics.

Date: July 16, 2014Source: Washington University in St. Louis

SCIENTISTS FIND WAY TO TRAP, KILL MALARIA PARASITE

• In order to live and reproduce the parasite invades red blood cells, taking part of their membrane to create a compartment, turning the red blood cells in your home, this is done by segregating different proteins.

• The parasite proteins are ejected by a single pore to the red blood cell. The Parasite proteins are different to those produced by the human being


Different studies seek to terminate a step in the growth of the parasite that causes malaria. New research has found that to kill malaria Parasite have to close the pore through which it communicates with the outside.

It is believed that by blocking the pore, the parasite is fatally imprisoned, unable to steal resources from the red blood cell or eliminating waste.


A different research, studying a protein "thermal shock" HSP 101, so named because it acts when the cell is heated. The HSP 101 has different functions as guide the folding and unfolding of proteins of the parasite that causes malaria, may also condition them for spending for the pore a in a linear manner and provide part of the energy necessary to pass through the pore.By blocking this protein, translocation can be prevented, among other things.


Malaria is a disease that affects millions of vulnerable people in the world, I find it necessary to seek different treatment alternatives to prevent many deaths and improve the quality of life for all people. Similarly, the different mutations of organisms, creates drug resistance, necessitating the invention of new drugs.

STEM CELL SCIENTISTS LAY TRAP FOR DISEASE

Date: July 11, 2014Source: University of Southern California - Health Sciences

Stem cells differ from other cells by several features. Ability to divide to produce new stem cells and their ability to generate mature specialized cells, under certain physiological conditions.


Acute renal failure is the rapid loss (about 2 days) the ability of the kidneys to remove waste and maintain fluid balance and electrolytes.

Acute renal failure may occur as a result of surgery, infection or drug toxicity for different treatments. This can lead to chronic kidney damage or death.


• Scientists at the Rockefeller Institute for Medical Research in 2008, invented a fluorescent marker for any cell ribosomes, TRAP (means "translating ribosome affinity purification.").

• With this they can determine which genes assets, ordered the production of proteins from ribosomes.

• Other researchers applied this technique in transgenic mice to take cellular and genetic information of different organs, including the kidney.


Some researchers used rats to identify four types of renal cells and identify early signs of acute kidney injury. Early detection of renal damage, could improve the health of patients, would allow other molecularly understand various diseases and functioning of organs to injury.


• I think this kind of research can have good results, not only to understand the operation of various diseases, their progression and complications, but also to find new forms of treatment.

• Always looking to improve the quality of life of patients.

MEDICAL UTILITY

Nowadays the molecular biology is being heavily used to find answers to crucial processes in the health of people. I think it is of great medical use to find new ways to treat diseases that evolve every day and become more difficult to combat.

MEDICAL UTILITYThe medicine must keep pace technologically or even faster with society, should always seek the welfare of people suffer every day from various conditions. As is the case of malaria, although Africa is the place where most often, in the Colombian jungles there are also a large number of people who die from this disease.

MEDICAL UTILITY

• Prevention is an important part of medicine, so I think it's necessary to make studies to determine the damage, without causing this, everything to ensure the effectiveness of the treatment to which the patient undergoes. In acute kidney disease may not know the damage that is generated until after this is done, if known earlier could prevent many deaths.

MEDICAL UTILITY

Technology should be a tool for the physician should understand and use it in the best way for the welfare of the patient. We need further research to have better arguments to fight disease. Experiments with rats have been used for many years for answers in humans, it has made great progress and can even more.

REFERENCES• SCIENCE DAILY. Scientists find way to trap, kill malaria

parasite. http://www.sciencedaily.com/releases/2014/07/140716131543.htm. [Consult july 18]

• SCIENCE DAILY. Stem cell scientists lay TRAP for disease. http://www.sciencedaily.com/releases/2014/07/140711153337.htm. [Consult july 18]

• HEALTHINNOVATIONS. Scientists find way to trap, kill malaria parasite. http://health-innovations.org/2014/07/17/scientists-find-way-to-trap-kill-malaria-parasite/ [Consult july 18]

• LÓPEZ GUERRERO, José Antonio. Células Madre: la madre de todas las células. 1ª.ed. Madrid: Helice,2003. 63 p.

THANK YOU VERY

MUCH.

molecular biology, daniela alarcón

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