module 6 making a case
DESCRIPTION
Module 6 Making a Case. Table of Evidence. Study types. Lit search?. Results consistent?. Valid?. Review. # studies/part. Outcome. Linde, 2005. 26/3320. RCTs. Yes. Yes. Yes. Moderate improvements for mild or temp depression ONLY. Whiskey, 2001. 14/1296. RCTs. Yes. No. Yes. - PowerPoint PPT PresentationTRANSCRIPT
![Page 1: Module 6 Making a Case](https://reader030.vdocuments.us/reader030/viewer/2022032804/56812abf550346895d8e865d/html5/thumbnails/1.jpg)
Module 6Module 6Making a CaseMaking a Case
![Page 2: Module 6 Making a Case](https://reader030.vdocuments.us/reader030/viewer/2022032804/56812abf550346895d8e865d/html5/thumbnails/2.jpg)
Review
Linde, 2005
Moderate improvements for mild or temp depression ONLY
Table of Evidence
# studies/part
Study types
Valid?
Litsearch?
Results consistent?
Outcome
26/3320 RCTs Yes Yes Yes
Whiskey, 2001
Moderate improvements for mild or temp depression ONLY
14/1296 RCTs Yes No Yes
![Page 3: Module 6 Making a Case](https://reader030.vdocuments.us/reader030/viewer/2022032804/56812abf550346895d8e865d/html5/thumbnails/3.jpg)
Study Intervention Duration Study Type Sample Outcome
Casper, 2006 600mg/daily 6-week RCT n= 205 Mean score (HMD)
123 I decreases: 82 C 11.6 for SJW 6.0 for placebo
Table of Evidence
![Page 4: Module 6 Making a Case](https://reader030.vdocuments.us/reader030/viewer/2022032804/56812abf550346895d8e865d/html5/thumbnails/4.jpg)
A – Recommendation based on consistent and good quality (level 1 study quality) patient-oriented evidence
SORT
Study Quality Diagnosis Scenarios Therapy/Prevention Scenarios Harm/Etiology Scenarios
![Page 5: Module 6 Making a Case](https://reader030.vdocuments.us/reader030/viewer/2022032804/56812abf550346895d8e865d/html5/thumbnails/5.jpg)
A – Recommendation based on consistent and good quality (level 1 study quality) patient-oriented evidence B – Recommendation based on inconsistent and limited quality (level 2 study quality) patient-oriented evidence
SORT
Study Quality Diagnosis Scenarios Therapy/Prevention Scenarios Harm/Etiology Scenarios
![Page 6: Module 6 Making a Case](https://reader030.vdocuments.us/reader030/viewer/2022032804/56812abf550346895d8e865d/html5/thumbnails/6.jpg)
A – Recommendation based on consistent and good quality (level 1 study
quality) patient-oriented evidence B – Recommendation based on inconsistent and limited quality (level 2 study quality) patient-oriented evidence C – Recommendation based on consensus, usual practice, opinion (level 3)
study quality) disease-oriented evidence
SORT
Study Quality All Scenarios
![Page 7: Module 6 Making a Case](https://reader030.vdocuments.us/reader030/viewer/2022032804/56812abf550346895d8e865d/html5/thumbnails/7.jpg)
Patient-oriented evidence measures outcomes that matter to patients: morbidity, mortality, symptom improvement, cost reduction, and quality of life.
Disease-oriented evidence measures intermediate, physiologic, or surrogate end points that may or may not reflect improvements in patient outcomes (e.g., cholesterol levels, blood chemistry, physiologic function, pathologic findings).
SORT
![Page 8: Module 6 Making a Case](https://reader030.vdocuments.us/reader030/viewer/2022032804/56812abf550346895d8e865d/html5/thumbnails/8.jpg)
Ebell MH, et al. 2004. Strength of Recommendation Taxonomy (SORT): A Patient-Centered Approach to Grading Evidence in the Medical Literature. American Family Physician 69(3):548-556.
SORT
![Page 9: Module 6 Making a Case](https://reader030.vdocuments.us/reader030/viewer/2022032804/56812abf550346895d8e865d/html5/thumbnails/9.jpg)
Form a clinical question (PICO, search query)
Find evidence (research)
Make a case
Three simple steps
![Page 10: Module 6 Making a Case](https://reader030.vdocuments.us/reader030/viewer/2022032804/56812abf550346895d8e865d/html5/thumbnails/10.jpg)
Module 6Module 6Making a CaseMaking a Case