mitosis2
TRANSCRIPT
![Page 1: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/1.jpg)
MitosisWhat is it?Why is it Important?
What do I need to know?
![Page 2: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/2.jpg)
Why more cells? Populations of
single-cell critters Multicellularity? We all start out as
a single cell…? The zygote… & become/remain
multicellular
![Page 3: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/3.jpg)
Binary Fission…Monera
![Page 4: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/4.jpg)
Binary Fission..DNA duplicates…why?
![Page 5: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/5.jpg)
DNA separates & new cell wall divides cell in two
![Page 6: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/6.jpg)
2 ‘new’ cells…identical?
![Page 7: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/7.jpg)
Binary Fission
![Page 8: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/8.jpg)
quiz What happens to the size of bacteria
after binary fission? What has to happen before fission
occurs? What benefit(s) do bacteria derive
from binary fission (as opposed to sexual reproduction)?
![Page 9: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/9.jpg)
Eukaryotic cells?? The nucleus? Nuclear membrane Chromosomes…
not chromosome…?
All that ‘stuff’ in the cytoplasm?
![Page 10: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/10.jpg)
Eukaryotic cell cycle Cell is ‘born’ Duplicates DNA?? Grows to…size? Prepares to divide Divides=mitosis
![Page 11: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/11.jpg)
![Page 12: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/12.jpg)
![Page 13: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/13.jpg)
Control of mitosis:CYCLIN
![Page 14: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/14.jpg)
The nuclelus must first divide before the cell can
Why? How? How much time of
the cell cycle/life can be spent in mitosis?
![Page 15: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/15.jpg)
Chromosomes duplicate
![Page 16: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/16.jpg)
![Page 17: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/17.jpg)
![Page 18: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/18.jpg)
![Page 19: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/19.jpg)
![Page 20: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/20.jpg)
Kinetochore (centromere)
![Page 21: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/21.jpg)
![Page 22: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/22.jpg)
![Page 23: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/23.jpg)
![Page 24: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/24.jpg)
![Page 25: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/25.jpg)
![Page 26: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/26.jpg)
![Page 27: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/27.jpg)
![Page 28: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/28.jpg)
![Page 29: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/29.jpg)
![Page 30: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/30.jpg)
Mitosis produces identical offspring (2N---2N)
![Page 31: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/31.jpg)
Why some cells stop mitosis…differentiation
Muscle cells… Nerve cells… Critical functions
might be disrupted Adaptations to this
condition
![Page 32: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/32.jpg)
Importance??? Growth Replacement Cancer Regeneration of…
![Page 33: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/33.jpg)
Cancer? Unregulated
mitosis Benign Malignant/
metastasis How does it begin?
![Page 34: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/34.jpg)
Normal cycle controls Internal signals External signals:
growth factorsfibronectin,etccarcinogens
Apoptosis Immune functions And…
![Page 35: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/35.jpg)
Cell immortilization!! Hayflick limit?? Hela cells Contact inhibition Increased
telomerase activity = immortalization!
![Page 36: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/36.jpg)
Immortalization??? If you replaced… Why not??…look at
your shoestrings? Telomerase &
telomeres & …? Recently… Implications???
![Page 37: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/37.jpg)
Mitosis quiz Use two words to describe the
importance of mitosis Draw and label the cell cycle…
include G1, S, G2, M and cytokinesis…what happens at each stage?
Why might telomerase be important? What disease is associated with
mitosis? Are all organisms limited to 50 mitotic
divisions?
![Page 38: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/38.jpg)
Name stage of mitosis
![Page 39: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/39.jpg)
Name stage of mitosis
![Page 40: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/40.jpg)
Name stage of mitosis
![Page 41: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/41.jpg)
Name stage of mitosis
![Page 42: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/42.jpg)
Name stage of mitosis
![Page 43: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/43.jpg)
Name stage of mitosis
![Page 44: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/44.jpg)
Name stage of mitosis
![Page 45: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/45.jpg)
Name stage of mitosis
![Page 46: Mitosis2](https://reader036.vdocuments.us/reader036/viewer/2022062420/55b7f7dcbb61eb116d8b45c5/html5/thumbnails/46.jpg)
These are bacteria Watch the clip What kind of
reproduction is shown here?
What advantage does this confer on the organism?