microsoft powerpoint - 18ph2drug1.ppt [compatibility mode]
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PREVENTION ofDRUG USE and
DRUG USEDISORDERS
Renato M. Espinoza, MD, MHPEd
Dr Francisco Q. Duque Medical Foundation
Preventive Health and Community Medicine
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Goals and Objectives
To understand drug-related roble!s and t"eir
i!lications to co!!unit# "ealt" define ter!inologies$ diagnose drug-related roble!s
To beco!e effective "ealt" %or&ers in t"erevention of drug !isuse and associated disorders
discuss !ultilevel drug abuse reventive !easures
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Drug-relatedproblems are true
masquerades inclinical practice
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Important Facts T"e onset of drug use is !ost co!!on during t"e late
c"ild"ood and adolescent #ears. T"e onset of drug abuse and deendence is !uc" !ore
deendent on genetic variation in co!bination %it" secific
environ!ental factors.
Pro/i!al and distal biological$ s#c"ological$ social andenviron!ental recursors originating as earl# as t"e renatal
eriod la# a large role in %"et"er e/eri!entation occurs
and use ersists.
0or so!e individuals$ t"e initiation of drug !isuse and illicituse of drugs e/tends be#ond adolescence$ even in t"e late
adult"ood.
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PHARMACOLOGY OFDRUGS OF ABUSE 0our rocesses are i!ortant to t"e develo!ent
of drug abuse2 exposure
physical dependence
psychological dependence
tolerance
3n understanding of t"e "ar!acological
roerties of drugs is essential to t"e
understanding of drug abuse and deendence and"ence t"e design of revention interventions.
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Important processes in
Drug Ause an!Drug Depen!ence
"# E$posure - ti!ing and fa!ilial(genetic suscetibilit#
%# P&'sica( !epen!ence - adative state t"at !anifests itself
as intense "#sical disturbance %"en drug use is susended
)# Ps'c&o(ogica( !epen!ence - addiction$ condition under
%"ic" t"ere is a drive to%ard eriodic or continuous
ad!inistration of t"e drug to roduce leasure or avoid
disco!fort
*# +o(erance - t"e need for increasingl# "ig"er doses of a
drug to recature t"e original effects of t"e drug
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Drug 3buse andDrug Deendence Processes o, ause an! !epen!ence re,(ect c&aracteristics o,
t&e !rug- t&e in!i.i!ua( user an! t&e conte$t o, use# Among t&e goa(s o, ps'c&op&armaco(og'- epi!emio(og' an!
etio(og' researc& is to gain a etter un!erstan!ing o, t&e
processes imp(icate! in t&e !e.e(opment o, !epen!ence ase!
on t&e !rug- t&e user an! t&eir interactions /it& one anot&er#
+&e more rein,orcing t&e !rug is t&e more (i0e(' t&e in!i.i!ua(
/i(( see0 t&e !rug an! ause it# +&is is ca((e! abuse liabilityo,
t&e !rug#
Drug ause ma' resu(t ,rom one e$posure on('#
e$amp(e1 binge drinking on t&e ,irst occasion o, a(co&o( use
or !ri.ing a .e&ic(e under the influence of an illicit drug#
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6o!!onl#-abusedGrou of DrugsCannabinoids
Depressants
Dissociative Anesthetics
Hallucinogens
Opioids and Morphine Derivatives
Stimulants
Inhalants
Anabolic Steroids
Overthecounter !O"C# Drugs
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cannabinoids fro! t"e flo%ering to of t"e "e! lant
!ore t"an ,* cannabinoids "ave been isolated delta-7-T86 "as been identified as t"e constituent
resonsible for !ost of t"e c"aracteristic effectssuc" as cognition$ !e!or# and !ood disorders$
!otor incoordination$ errors in ercetion$disorder in t"e sense of ti!e$ feelings of rela/ationand %ell-being$ increased "eart rate$ differentiall#altering standing and suine 9P
%it"dra%al s#!to!s2 irritabilit#$ restlessness$nervousness$ decreased aetite$ %eig"t loss street na!es2 "as"$ resin$ :;$ 3caulco gold$ ot..
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depressants A# ariturates
S&are se!ati.e an! &'pnotic properties
Use! me!ica((' to pro!uce !ro/siness- s(eep- musc(e re(a$ation an! topre.ent con.u(sions
Ha.e anest&etic e,,ects
Dose2!epen!ent e,,ects on re(a$ation- se!ation- &'pnosis an! stupor
B# en3o!ia3epines Hig& an$io('tic propert' an! (o/ C4S !epressant properties
Re(ie.e an$iet' s'mptoms Less impaire! respirator'- cogniti.e- attention an! motor ,unctions
In genera(- !epressants &a.e comp(e$ e,,ects#
+o(erance ,or an! Depen!ence on t&e .arious !rugs o, t&is c(ass
genera(i3e /it&in t&e c(ass an! across c(asses to some opiates an!a(co&o(- ca((e! cross tolerance or cross dependence
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dissociative anesthetics Inc(u!es PCP5p&enc'c(ine6- 7etamine an!
De$tromet&orp&an
PCP De.e(ope! in t&e "89:s as I; genera( anest&etic ,or anima(s Se!ati.e an! anest&etic e,,ects are trance2(i0e
Patients e$perience a ,ee(ing o, out o, o!'
Distorte! perception o, sig&t an! soun!
Fee(ings o, !etac&ment or !issociation ,rom t&e en.ironment
an! se(, 5 not &a((ucinations 6 Mec& o, action1 a(tering t&e !istriution o, t&e
neurotransmitter GLU+AMA+E t&roug&out t&e rain
G(utamate is in.o(.e! in t&e perception o, pain responses toen.ironment an! memor'
7E+AMI4E De.e(ope! in "8ui! ,orm
E.aporate! into an o!or(ess an! taste(ess po/!er an! it is
use! as !ate rape !rug
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hallucinogens No accetable !edical use
Includes2 !escaline$ silocin and
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opioids and morphine Effects2 analgesia$ sedation$ eu"oria
:ec" of action2 sti!ulation of t"e "ig"er centersof t"e brain and slo% do%n t"e activit# of t"e 6NS
Oiod refers to t"e natural drugs roduced fro!
t"e oiu! o# suc" as oiu!$ !or"ine and
codeine
Se!i-s#nt"etic oiates2 "eroine and !et"adone
:edical uses2 ain !anage!ent$ diarr"ea$ coug"
T"ese grou of drugs are "ig"l# addictive
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stimulants E/citator# in recognition of t"eir !ain effects in t"e 6NS
Increases t"e levels of doa!ine and decreases in"ibitor#neurotrans!itter
Includes cocaine$ a!"eta!ines$ and !et"#l"enidate
In lo% doses$ are associated %it" feelings of increasedalertness$ eu"oria$ vigor$ !otor activit#$ and aetite
suression 3t "ig" doses$ t"e# roduce convulsions$ c"anges in t"oug"t
c"aracteri=ed on continuu! fro! "#er-vigilance to susicionto aranoia$ a!"eta!ine and cocaine induced s#c"oses$aranoid ideation$ or to/ic cardiovascular s#!to!s
6ocaine$ %"en co!bined %it" alco"ol$ roduces t"e let"alcocaethylene.
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inhalants Di.erse group o, c&emica(s t&at easi(' e.aporates E$amp(es1 aeroso(s- gases- &'!rocaron in&a(ants suc& as
so(.ents- gaso(ine an! paint t&inner
?&en .apors are in&a(e! an! e$&a(e! air is rereat&e!-
into$ication is pro!uce!# ;apors o, (i>ui! so(.ents can e sni,,e!!irect(' ,rom a container- ma' e poure! on a rag an! &e(! o.ert&e mout&- or ma' e emptie! into a rag t&at is &e(! o.er t&emout& an! nose ,or in&a(ation
Mec& o, action1 in&a(e! .apors enter t&e (oo!stream rapi!('an! are !istriute! to (i.er an! rain an! are asore! >uic0('
into t&e C4S !epressing man' o!i(' ,unctions Genera((' t&e' are categori3e! as C4S !epressants# In mo!erate
!oses- t&e' pro!uce simi(ar e,,ects to t&at cause! ' a(co&o(1
Gi!!iness- Disin&iition an! Musc(e ?ea0ness
Lac0 o, Coor!ination- S(o/e! Re,(e$es an! S(urre!
Speec& Hig& !oses can cause se.ere reat&ing ,ai(ure an! !eat&
C&ronic ause (ea! to irre.ersi(e (i.er or rain !amage an!ot&er &ea(t& pro(ems#
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over-the-counter (OTC) drugs Include variet# of rearations %it" %"ic" eole self
treat for !inor ail!ents fro! t"e co!!on cold to ainrelief or to i!rove erfor!ance in so!e %a#
E/a!les2 sti!ulants$ slee en"ancers$ %eig"t controlroducts
:ost of t"ese roducts co!e in co!bination of drugst"at interact %it" one anot"er to roduce t"e !ost
ositive effect If ta&en as directed$ t"e# are relativel# safe
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other compounds 3re grou of drugs t"at do not fall into t"e
above categories
E/a!les2 anabolic steroids$ !ale se/"or!ones
:edical uses2 Dela#ed ubert#$ %"en t"e bod# roduce ver# lo%
a!ounts of testosterone Treating bod# %asting in 3IDS and related diseases
8ealt" conse>uences associated %it" abuse2 Reduced ser! roduction$ s"rin&ing of t"e testicles$
i!otence$ difficult# and ainful urination$ baldnessand irreversible breast enlarge!ent in !ales
Develo!ent of !asculine c"aracteristics li&edecreased bod# fat and breast si=e$ deeening of t"evoice$ e/cessive bod# "air$ and loss of scal "air infe!ales
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other compounds Anao(ic steroi!s are in=ecte!- ta0en ora((' or are rue! into
t&e s0in in an ointment ,orm
+&e use o, t&ese sustances are /i!esprea! among at&(etesmoti.ate! ' t&e !esire to ui(! musc(e an! impro.eper,ormance
Most ausers ta0e !oses o, up to "::$ greater t&an at&erapeutic !ose
Hea(t& conse>uences associate! /it& ause1
For a!o(escents o, ot& gen!ers- ause can resu(t intermination o, t&e gro/t& spurt t&us permanent('stunting gro/t&
Ot&er se.ere &ea(t&- socia(- an! ps'c&o(ogica(conse>uences occur ,or ausers o, ot& gen!ers at a((ages- inc(u!e1
C(otting
Li.er c'sts an! cancer
C&o(estero( c&anges Heig&tene! aggression
Depresse! moo!
Insomnia
Loss o, appetite
Musc(e an! =oint pains
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Su!!ar# of 8all!ar&sAmp&etamines5inc(u!ingmet&&etamines6
Aggressi.e or o.eracti.e
e&a.ior- gigg(ing- si((iness-eup&oria- rapi! speec&-con,use! t&in0ing- no appetite-e$treme ,atigue- !r' mout&-s&a0iness
@ars o, pi((s o,
.ar'ing co(ors-c&ain smo0ing
H'pertension- !eat&
,rom o.er!ose-&a((ucinations-met&&etaminescause temporar'ps'c&osis
9arbiturates Dro%siness$ stuor$ dullness$slurred seec"$ drun&
aearance$ vo!iting
Pills of various
colors
Deat" fro! overdose or as
a result fro! %it"dra%al
addictions$ convulsions
6annabis(:arijuan
a
Initial eu"oria$ floating feeling$
sleeiness$ let"arg#$ %andering!ind$ enlarged uils$ lac& of
coordination$ craving for s%eets$
c"anges of aetite$ !e!or#
difficult#
Strong odor of burnt
leaves$ s!all seedsin oc&et lining$
cigarette aer$
discolored fingers
Induce!ent to ta&e
stronger narcotics$ recent!edical findings reveal
t"at rolonged usage
causes cognitive defects
Ecstac#?!et"#lenedio/#-
!et"a!"eta!ine@
3n/iet#$ anic$ s%eating$ loving
feelings$ ja% clenc"ing$ teet"
grinding$ bi=arre overactive
be"avior$ "allucinations$
increased "eart rate$ 9P and
bod# te!erature$ feelings of
confidence$ "ainess and love
S!all tablets of
various colors$
s"aes$ si=es and
designs$ also co!es
in casule or
o%der
6onvulsions$ ris& of deat"
fro! "eart attac&$
cerebral "e!orr"age$
"#ert"er!ia$ fluid
i!balance %it"
"#onatre!ia$ acute
&idne# failure$ DI6$ liver
to/icit#
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Fantas' 5gamma
&'!ro$'ut'rate6
Re(a$ation an!
!ro/siness- !i33iness-re(a$e!in&iitioneup&oria-increase! se$ua(arousa(- impaire!
moi(itu' an! speec&
Co(or(ess
(i>ui!A(so po/!eran! capsu(es
+remors an!
s&a0ing- amnesia-coma- con.u(sions-!ea& ,rom &ig&!oses
Glue sniffing 3ggression and
violence$ drun&
aearance$ slurred
seec"$ drea!# or
blan& e/ression
Tubes of glue$
glue s!ears$
large aer or
lastic bags or
"and&erc"iefs
uid
Suicidal tendencies$
unredictable
be"avior$ c"ronic
e/osure causesbrain da!age$
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Narcotics
a6 Opioi!s5&eroin6
Stupor!ro/siness-mar0s on o!'-/ater' e'es- (oss o,appetite- runningnose- narro/e!
pupi(s- (oss o, se$!ri.e
4ee!(e or&'po!ermics'ringe- cotton-tourni>uet# string-rope- e(t- urnt
ott(e- caps orspoons- (oo!stainon s&irt s(ee.es-g(ass in en.e(opes
Deat& ,rom o.er!ose-menta( !eterioration-!estruction o, rainan! (i.er- &epatitis-emo(isms
9@ 6ocaine Si!ilar effects to
a!"eta!ines
?!uscle ains$
irritabilit#$ aranoia$
"#eractivit#$ jer!ove!ents
eu"oria$ dilated
uils
Po%der2 in
!icro%ave ovensA
in"aled or injected
8allucinations$ deat"
fro! overdose
Bsudden deat" fro!
arr"#t"!ias$ sei=ures$
!ental disorders$severe resirator#
roble!s
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STREET DRUG DICTIONARY
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AMPHETAMINES (uppers)
Ben3e!rineDe$e!rineMet&e!rineDrinam'(
Roses- eanies- peac&esDe$ies- spee!- &earts- pep pi((s- ,ast- go2ee- uppersMet&- cr'sta(s- /&ite (ig&t- ice- /&i3Purp(e &earts- goo, a((s
AMPHETAMINEDERIVATIVES
Ecstac#
6rac&
6ran&
E$ eggs$ ec&ies$ CT6$ t"e love drug$ !itsubis"is$ :D:3$ vita!in E$
C$ 3da!$ deat"
6rac&$ slit$ base(sace base ?%it" "enc#clidine@
6r#stal :$ cran&
HALLUCINOGENS
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NARCOTICSMorp&ine
Heroin
Cocaine
H C
Mor&- Miss- Emma
H- ig H- Harr'- GOM 5Go!s o/n me!icine6- crap- =un0-&orse !'namite5&ig&2gra!e &eroine6- (emona!e5(o/2gra!e
&eroine6- In=ection o, !isso(.e! po/!er1 mainlining$blast$ smack$In&a(ation o, po/!er1 sniffing
Co0e- sno/- (a!' o, t&e streets- nose can!'- ICE- snort
Spee! a((s
MISCELLANEO
US
0antas#
9arbiturates9en=odia=eines
Feta!ine
Solvents
G98 ?grievous bodil# "ar!@$ li>uid G$ li>uid ecstac#$ li>uid C
Devils barbies$ goof balls
Ro%ies$ !oggiesF. Vita!in F$ secial F$ F "ole
6"ro!ing
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EPIDEMIOLOGY OFDRUG USE
Understanding t"e nature$ e/tent and atterns of
use and abuse of s#c"oactive drugs andco!ounds is a necessar# rere>uisite to t"e
develo!ent of efficacious and effective
revention interventions.
Understanding t"e causal factors t"at lead to
e/osure$ initiation$ rogression$ and !aintenance
of drug abuse is funda!ental to t"e advance!entof revention strategies.
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ETIO
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ETIO
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MACROSYSTEM
ATTITUDES AND IDEOLOGIES OF THE CULTURE
EXOSYSTEM EXTENDED
FAMILY
NEIGHBORS
FRIENDS
OF FAMILY
LEGAL
SERVICES
MASS
MEDIA
SOCIAL WELFARE
SERVICES
MESOSYSTEM
FAMILY
MICROSYSTEM
SCHOOL
PEERSHEALTH
SERVICES
NEIGHBORHOOD
PLAY AREA
DAYCARE CENTER
CHURCH
GROUP
CHILDCHILDCHILDCHILD
BRONFENBRENNERBRONFENBRENNERBRONFENBRENNERBRONFENBRENNERS FOUR ECOLOGICALS FOUR ECOLOGICALS FOUR ECOLOGICALS FOUR ECOLOGICAL
SETTINGS FOR DEVELOPMENTAL CHANGESSETTINGS FOR DEVELOPMENTAL CHANGESSETTINGS FOR DEVELOPMENTAL CHANGESSETTINGS FOR DEVELOPMENTAL CHANGES
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T8EORETI63