ADICTION *

*Case of “Meth”

AD.DIC.TION: is defined as the continued use of a mood altering substance or behavior despite adverse consequences. This can include, but is not limited to, alcohol abuse, drug abuse, exercise abuse, and gambling. Some defining characteristics of addiction include: impaired control over substances/ behavior, preoccupation with substance/ behavior, continued use despite consequences, and denial.

METH- AMPHETAMINE

METHAMPHETAMINE

LIC

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ILLICIT>

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production

1. Uses

ADHD*

Disinhibition

Forgetfulness

Inattention

Hyperactivity

Disorganization

Distractedness

*Attention Deficit Hyperactivity Disorder

1. Uses (OBESITY, NARCOLEPSY, DEPRESSION, )

others

1. Uses (OBESITY, NARCOLEPSY, DEPRESSION, )

others

1. Uses (OBESITY, NARCOLEPSY, DEPRESSION, )

others

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production

Some

1. Uses 2. Effects (Physical) 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production

Anorexia

1. Uses 2. Effects (Psychological) 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production

Anxiety

1. Uses 2. Effects (Withdrawal) 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production

Fatigue

1. Uses 2. Effects (Long-term) 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production

Suicide

1. Uses 2. Effects (Tolerance) 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production

Adverse Effects

1. Uses 2. Effects (Physical) 3. Adversity

Addiction

1. Uses 2. Effects (Physical) 3. Adversity

“Meth- Mouth”

1. Uses 2. Effects (Physical) 3. Adversity

Public Health Issues

WASTE

EXPLOSIONS BURNS

1. Uses 2. Effects (Physical) 3. Adversity

Pregnancy & Breast-

feeding

in

1. Uses 2. Effects (Physical) 3. Adversity

Sexually- transmitted

diseases

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production

Ball-and-stick model of the meth- amphetamine molecule

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production

Nature! in

in Texas

ACACIAS

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production

ROUTES

6. Administration

Injection

6. Administration

Smoking

6. Administration

Insufflation

6. Administration

Suppository

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History ( D i s c o v e r y ) 8. Production

synthesized from ephedrine

Japan In 1893

by chemist Nagai Nagayoshi

methyl alpha-methylphenylethylamine

Term derived from…

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History ( M i l i t a r y ) 8. Production

World War II

Adolf Hitler used it

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History (Medical and legal over-the-counter sales) 8. Production

In 1943

such as chronic alcoholism

Medical and legal over-the-counter sales

requested FDA approval

for medical treatments

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History (………………………………………………………………….) 8. Production

1950s: Banned in Japan

2000s Other drugs surpassed

1970s Regulated in US

1980s Increased Abuse

Recreational use & prohibitive regulations

1990s New forms appeared

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History ( S T A T U S ) 8. Production

production, distribution, sale and possession…

is restricted or illegal in many jurisdictions

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production

Illicit

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production (Syntesis)

CRYSTAL

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production (Distribution)

industrial-scale chemical factory 1 lb (454 g)

1. Uses 2. Effects 3. Adversity _. Pharmacokinetics 4. Pharmacology 5. Occurrence 6. Administration 7. History 8. Production ( S L A N G )

“crystal”

“ice”

“p”

“shaboo”

“singolah”

“bunzun” “crank”

“glass”

“white”

“jib” “batu”

“scante”

“trigo” “rizz”

“tina”

“czecho”

“fast” “speed”

common 4 most of RELAPSE

> + + + =

causes