Predictive Genomics is the area of medicine that deals with the detection of specific “chang-es” in DNA called mutations. These mutations determine desirable or undesirable traits and have been associated with risk for common polygenic multifactorial diseases.

Disease depends not only on the genetic fac-tors but also on environmental influences as well as the lifestyle of the individual. In the era of Preventive Medicine, knowledge of our ge-netic profile is an absolute necessity for achiev-ing and maintaining optimal health. To avoid and manage disease, the insight obtained from DNA genetic screening is vital for imple-menting preventive measures and perform-ing appropriate corrective actions. The genetic recommendations will provide longevity and improved life quality.

new biotechnology

Genetic Screening based on Preventive and Personalized Management of Diseases

Discover your Genes and Stay Healthy !

Personalized Medical Care

according to your Genes

Do i need to be aware of my genetic profile to maintain my health?

There are multiple interactions between our genes and our health. The medical advice

based on the genetic profile is personal-ized regarding the corrective actions and

the regular attendance at the doctor for screening. However, for an individual that is not as health conscious, the genetic information provided may not have the same value as it would to an advocate on

the belief that prevention is better than cure.

The Genetic Screening for Medical Care provides the basis for establishing

a path for improved long-term health and quality of life.

Head Office: 70, Omirou str. - GR 171 21 Nea SmyrniTel. / Fax: +30 210 9319050 & +30 210 9370222

E-mail: genomed@genomed.gr www.genomed.gr

Health & Medical Care

Health & Medical Care

Predictive Medicine is based on early detection of the risk

for several human illnesses. Based on the Genetic Profile,

appropriate pharmacological, nutritional, environmental

guidelines and lifestyle choices are recommended. These

guidelines are individualized, personalized and more spe-

cific than the universal recommendations applicable to the

general population.

New Genomed biotechnology offers genetic screening

analyzing genes and mutations with strong associations to

the various biological systems investigated, all of which are

documented in the medical and scientific bibliography.

Genes Analyzed

Sampling process and turnaround time

DNA sampling is painless and does not require blood. It involves taking cells from the inside of the cheek with a specialized and sterilized buccal swab. The procedure lasts no more than a minute. Results are usually available within 15 working days. The confidential nature of personal data is strictly respected.

TYPE 2 DIABETES ACE CDKAL1 HHEX IGF2BP2 MTNR1B PPAR-γ

TNF-a IL6 VDR TCF7L2 SLC30A8

BONE HEALTHOSTEOPOROSIS

ACE PPAR-γ TNF-a IL6 VDR COL1A1

ESR1 PvuII ESR1XbaI CTR

RHEUMATOID ARTHRITIS

HLA-DRB1 PTPN22 STAT4 TRAF1-C5

ANKYLOSING SPONDYLITIS

HLA-B*27 B*2701/B*2725 ARTS1 IL23R

ALZHEIMER’S DISEASE APOE GALP SERPINA13 PCK1 TNK1

TOMM40 APOC1

PHARMACOGENOMICSWARFARIN SENSITIVITY

VKORC1 CYP2C9

EFFICACY OF DRUGSAspirin and Coagulation LPA ITGB3

Beta Blockers and High Blood Pressure ADRB1

Beta Blockers and Heart Failure ADRB1

Statins, Cholesterol and Heart Disease HMGCR

Antidepressants ABCB1

NUTRIGENOMICSCARDIOVASCULAR HEALTH

LIPID METABOLISM

APOA1 APOA5 APOB APOC3 APOE CETP

GJA4(CX37) HMGCR LIPC LPL PON1

HOMOCYSTEINE METABOLISM

CBS COMT MTHFR MTR MTRR TCN2

IRON ABSORPTION & STORAGE

HFE

INFLAMMATORY RESPONSE

CRP TNFa IL6

ANTIOXIDATION AND DETOXIFICATION

CAT EPHX1 GPX1 GSTM1 GSTP1 GSTT1

SOD2(MnSOD) SELS SOD3 UCP2

HYPERTENSION

ACE ADD1 AGTR1 AGT CYP11B2

CANCERSBASAL CELL CARCINOMA BLADDER CANCER

TERT MYC TERT

BREAST CANCER (PREDICTIVE)

LUM BRCA1 BRCA2 CASP8 CHEK2

FGFR2 TP53 TNRC9/TOX3

COLORECTAL CANCER

AURKA CASP8 CHEK2 GSTT1 TP53

PROSTATE CANCER

CHEK2 CYP17 ESR2 GSTT1 IGF1 TERT

BREAST CANCER (PATHOGENIC MUTATIONS)

BRCA1 BRCA2

VENOUS THROMBOEMBOLISM APOB Factor II Factor V Factor VII FGB

HFE MTHFR PAI-1

LUNGS AND BREATHINGASTHMA SUSCEPTIBILITY

GSTM1 GSTP1 GSTT1 IL6 ORMDL3

PTGS2(COX2) SPINK5 TNF-a

ASTHMA DRUG RESPONSE

ADRB2

CLUSTER HEADACHES ΗCRTR2

PHARMACOGENOMICS: TRIPTANS GNB3

CYSTIC FIBROSIS LACTOSE INTOLERANCE CFTR DeltaF508 MCM6

Genes screened relate to the following biological processes:

Neoplasia [Cancer]• Programmed Cell Death• Cell Cycle Regulation• Tumor Suppression

Thrombosis• Blood Clot Inhibition • Coagulation Factors

Asthma• Asthma Drug Response

Cluster Headaches

Cystic Fibrosis [ΔF508]

Type 2 Diabetes

Bone Health• Osteoporosis• Rheumatoid Arthritis• Ankylosing Spondylitis

Alzheimer’s Disease

Pharmacogenomics• Drug Metabolism• Efficacy of Drugs

Cardioascular Disease

Nutrigenomics• Antioxidation - Detoxification• Iron Absorption & Storage• Inflammatory Response• Hypertention

Predictive Medicine is based on early detection of the risk for several human illnesses. Based on the Genetic Pro� le, appropriate pharmacological, nutritional, environmental guidelines and lifestyle choices are recommended. These guidelines are individualized, personalized and more speci� cthan the universal recommendations applicable to the general population.

GENOMED in collaboration with the Central Laboratory Re-search Diagnostics, (ISO 17025 certi� ed, spin-o� company of the University of Athens, Scienti� c Director Nikolaos Dra-koulis, MD, PhD), developed Predictive Genomic Services in Greece and Internationally. This collaboration o� ers the high-est standards in methodology as well as professional counsel-ling in connection to multifactorial disease development.