Crystallise & permanently

remove the fat

Medical Cryolipolysis

www.deleo.frwww.deleo-medical.com

EVO

LUTI

ON

The reference

More than 500 000 treatments performed

10 morphological applicators, for body & face

Simultaneous use of 2 applicators

0 consumables

EC medical marking approved by BSI

Proven effective through 2 clinical studies

IN NUMBERS

More than 600 devices around the world

Deleo engineers have developed a new evolution of the CRISTAL device. CRISTAL is now equipped with the latest technology innovations for easier treatments and better results.

MORE APPLICATORSThe new CRISTAL evolution directly integrates the 3 mini-applicators from the AGATE set, to treat small areas. CRISTAL now offers you the possibility to treat all areas of the body with only one device !

MORE ERGONOMICThis new system is lighter and easier to maneover in your clinic to facilitate treatments.

MORE SECURITYCRISTAL has been developed in compliance with all European medical standards. CRISTAL is equipped with the latest security technology to warrant it the safest cryolipolysis device on the market.

NEW CRISTAL EVOLUTION

Cryolipolysis applies intense cold to localised fat folds through the use of high pressure suction with to induce ischemia, which modifies the configuration of adipocytes.

This change in the state of the cell, due to the normal body temperature (37C°) being reduced to negative temperatures (from -2C° to -9C°), sends a chemical message of apoptosis to the adipocytes. Thus? lipid content is released, dead cells are progressively evacuated via the lymphatic system & fat cell density decreases.

This safe and effective technique is non-invasive and requires no anesthesia. After 8 weeks, the result is optimal and definitive. CRISTAL offers the widest range of applicators to handle all the curves of the body, for both men and women.

PRINCIPLE OF CRYOLIPOLYSIS

3. Macrophages gather the crystallised fat cells, which are then permanently eliminated by the lymphatic system.

2. The cold crystallises the fat cells and causes their apoptosis(death of adipocytes).

4. The body, rid of excess adipocytes, is transformed over weeks, with a final result obtained within 2 months.

1. Fat cells in excess before CRISTAL treatment.

HOW ARE FAT CELLS DESTROYED BEFORE

AFTER

MORE PROFITABILITY, NO CONSUMABLES(except CRISTAL cryoprotective gel pads)

Greater and fast profitability for your business.

FOCUS ON SAFETYCRISTAL is the safest body contouring device on the market.• 15 temperature sensors• Medical CE marking, issued by the notified body B.S.I.

PROVEN EFFECTIVE THROUGH CLINICAL STUDIESDeleo works closely with a board of medical experts and has 2 CRISTAL clinical studies* that have been published and are available at www.deleo-medical.com

ERGONOMIC AND EVOLVING SOFTWARECRISTAL offers on-board electronics at the forefront of technology.• Fully customisable, touch sensitive & intuitive interface• Pre recorded protocols • Recording of your own protocols

PATENTED TECHNOLOGYThe Deleo R&D engineering team creates and patents new technologies every year in the field of medical aesthetics. • Specific cooling unit (down to -9 C °)• «Cavity Cooling Diffusion SystemTM» Innovation: a homogeneous, targeted and ultra-secure cooling system.

MADE IN FRANCEThe French manufacturing guarantee for our customers. Product reliability and easy traceability of each component.

THE CLEAR CHOICE FOR MEDICAL CRYOLIPOLYSIS

* Pr. PASSERON T. (2017), Evaluation of tolerability and efficacy of the Cristal cryolipolysis treatment on the localised fat deposits in obese subjects. PhD Service de Dermatologie, Hôpital L’Archet 2, Nice.

* Naouri, M. (2016), Fat removal using a new cryolipolysis device: a retrospective study of 418 procedures. J Eur Acad Dermatology & Venereology, 31: e158–e160. doi:10.1111/jdv.13899.

Emerald applicator Small fat foldsIndications : Arms, bra folds, small love handles & knees

Sapphire applicator Polyvalent for most types of fat foldsIndications : Abdomen, love handles & thighs

Ruby applicator Large fat foldsIndications : Abdomen

Amethyst applicatorSpecifically intended for flat areasIndications : Saddle bags & thighs

A1 applicatorFace - small fat folds Indications: chin

A2 applicatorBody - small fat folds Indications: chin, knees, bra folds

A3 applicatorBody - medium fat folds Indications: multi-zones

THE IDEAL SOLUTION AGAINST SMALL FAT FOLDSThe AGATE set includes 3 mini interchangeable applicators, to treat localised fat folds on small areas of the body. The AGATE applicators are now directly integrated in the CRISTAL device to offer you a full cryolipolysis platform for both face & body.

This new applicator set offers many treatment opportunities :• 7.2 million patients worldwide are looking for a non-invasive solution to reduce their double chin*• 67% of overweight patients are embarrassed by their double chin*

MORPHOLOGICAL APPLICATORSCRISTAL offers the widest range of morphological applicators for treating all the curves of the body, for both men and women. All applicators are designed to fit perfectly to the patient’s morphology with maximum comfort.

Moreover, CRISTAL operates with two applicators, simultaneously, for efficiency and perfect results.

* American Society for Dermatologic Surgery. 2015 Consumer Survey on Dermatologic Procedures.

THE WIDEST RANGE OF APPLICATORS

AFTER THE SESSIONResults are not immediately visible after a session, because fat cells are gradually eliminated by the lymphatic system. After 6 weeks, the patient will begin to see results, but will continue to eliminate fat cells for up to 8 weeks after the session. It is important to do before and after pictures and to retake measurements of your patient during a follow-up visit. This will allow your patient to clearly see the results. This session is also an opportunity to talk with your patient about treating other areas and to draw up a complete treatment plan.

1. Before the first session, it is important to take pictures of the patient, as well as to measure the fat fold using a caliper and a tape measurer. Following this consultation you can define treatment parameters or select one of the pre-recorded protocols, to achieve patient goals.

5. At the end of the session, the CRISTAL device will automatically stop. Applicators should be carefully removed, as well as the CRISTAL cryoprotective gel pads. It’s important to massage the treated area for about ten minutes, in order to warm the frozen tissue and to accelerate the adipocyte removal process.

2. Once the patient is ready, apply the CRISTAL cryoprotective gel pad to the treatement area. In order to ensure the safety and effectiveness of the session, it is essential to only use the CRISTAL cryoprotective gel pads that have been specifically developed and tested for medical cryolipolysis.

4. One session lasts about 60 minutes, during which time the patient can relax, listen to music or read. This allows you the opportunity to take on other appointments. You just need to check in on the patient every 20 minutes, to ensure that the session is running smoothly.

3. Next, apply the applicator, the vacuum system pulls the fat fold into place inside the applicator and a homogeneous cooling begins. Regarding the AMETHYST applicator, specific for flat areas, there is no suction and it is held in position with special straps. CRISTAL allows for 2 applicators to be used simultaneously.

PROCEDURE STEP BY STEP

AFTER SALE SERVICEAll maintenance and updates are supported by our after-sales service during this period. Deleo has a reactive and qualified after-sales service, in order to bring total satisfaction to its customers:

• Dedicated hotline & phone assistance• Quick intervention and dispatch of spare parts

CONTINUOUS TRAININGIt is essential for Deleo to be able to provide a thorough initial training, followed by continuous training. Our training managers adapt to your needs, to train all of your staff in CRISTAL technology.

SCIENTIFIC BOARDWe work in collaboration with a committee of scientific experts. We deliver new technologies, clinical studies, as well as new protocols. You can talk with our experts during our workshops and ask your questions on the Deleo forum: www.deleo-medical.com

PREMIUM MARKETING PACKThe Premium Marketing Pack provides you with everything you need to communicate information about CRISTAL in your office. In addition, CRISTAL has strong media and digital coverage, which makes the treatment widely known.

DIGITALSOCIAL

NETWORKSPRESS DISPLAYTV BLOG

PATIENT RECRUITMENTDeleo helps you in your patient recruitment, thanks to its online directory, which counts thousands of visits each month : www.cryolipolysiscristal.com

Additionally, to offer a full treatment plan to your patients, Deleo has developed many tools, including a post-treatment guide. This guide contains tips and advice about nutrition, fitness and body care. Having a healthy lifestyle will help your patients to maximise and maintain lasting results.

AFTER SALES SERVICE SCIENTIFIC

BOARD

PREMIUM MARKETING

PACK

PATIENTRECRUITMENT

CONTINUOUS TRAINING

MORE THAN A DEVICE, A FULL CONCEPT

CRISTAL provides you with support every day to launch Medical Cryolipolysis in your practice. Our experts will be there to guide you through the set-up of your device and also to help you find new patients. Joining the CRISTAL community that ensures personalised and lasting support.

BEFORE AFTER CRISTAL

DR. SCHINAZI

BEFORE AFTER CRISTAL

DR. SCHINAZI

BEFORE AFTER CRISTAL

DR. SCEMAMA

BEFORE AFTER CRISTAL

DR. SCHINAZI

VISIBLE AND DEFINITIVE RESULTS

ABDOMEN & LOVE HANDLES

ABDOMEN & LOVE HANDLES

ABDOMEN

LOVE HANDLES

BEFORE AFTER CRISTAL

DR. SARFATI

BEFORE AFTER CRISTAL

DR. HADDAD

BEFORE AFTER CRISTALDR. SARFATI

BEFORE AFTER CRISTAL

DR. MALET

SADDLE BAGS

SADDLE BAGS

CHIN

CHIN

They have chosen CRISTAL®

and you ?

Dr. Thomas PROEBSTLEDermatologist, Mannheim - Germany

Dr. Hans-Joachim LAUBACH Dermatologist,Strasbourg - France

Dr. TONYAesthetic physician,Bangkok - Thailand

Dr. Rolf BARTSCH Plastic and aesthetic surgeon, Vienna - Austria

Dr. Triwiji NURDIASTUTIAesthetic physician, Jakarta - Indonesia

Dr. Eriko NISHIIKE DermatologistTokyo - Japan

Dr. Richard ABSPlastic surgeon, Marseille - France

Dr. Taimur SHOAIBPlastic surgeon, London - UK

Dr. John CURRANDermatologist Guernsey

A HIGH GROWTH MARKET

80.6% of patients expressed their desire for a second CRISTAL session. 3

Maurice DRAYAesthetic physician, London - UK & Paris - France

Dr. Iñigo DE FELIPEDermatologist,Barcelona - Spain

Dr. Muriel CREUSOTDermatologist,Lasne - Belgium

1 Source: Aesthetic Insight – August 28,20182 Source: Data Tribune 2017 (MII, DRG1) Non-invasive Fat reduction, Research & Market, Aug 16 3Source: Michaël Naouri M. Fat Removal Using a French Cryolipolysis Device: Retrospective Study of 418 Treatments.France. 2016.

Through 2022, the overall market for body contouring devices will expand by 14.7% per year 1

million body contouring procedures were performed this year. 1

Cryolipolysis is disrupting the competitive landscape in EBD with unparalleled forecasted growth rates of +26.6% . 2

2x

9

BROCHURE DOCTOR-CRISTAL EVOLUTION-EN-v3.1-051018This device was developed and manufactured in France by Deleo. It is a Class IIa Medical Device. This machine is legalized with the CE marking that indicates that this product meets the essential requirements of all relevant european medical device directives. Delivered to Deleo by the notified body BSI. Please read instructions before use. Do not use the device other than specified in the instructions.

Our quality system for the manufacturing of medical devices (ISO 13485 : 2003 et EN ISO 13485 : 2012) ensures compliance with the highest medical standards.

Power output & input AC 220-240V 50Hz Max8A Alimentation 1200W

Software PC Android 4.3 tactile

Temperature From 10°C to -9 °C

Structure Painted or anodized aluminum

Cooling system4 Peltier cooling blocks, Cooling

unit that uses gas R134a

Dimensions 100 x 60 x 46 cm

Max weight 53Kg (with option)

80.6% of patients expressed their desire for a second CRISTAL session. 3

TECHNICAL SPECIFICATIONS

DELEO S.A.S.300, RUE ISAAC NEWTON

TECHNOPARC EPSILON 1

83700 SAINT RAPHAEL FRANCE

T. +33 (0)4 94 45 83 75contact@deleo.fr

Medical Cryolipolysis

We remain at the forefront in our field of expertise and regard each privileged relationship with our customers as our key priority.

Discover all of our products at :

www.deleo-medical.com