mcb 142/icb 163, fall 2008 © abby dernburg

MCB 142/ICB 163, Fall 2008 © Abby Dernburg

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Quiz and midterm dates on syllabus posted on course website!http://mcb.Berkeley.EDU/courses/mcb142/

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MCB140, Jan. 23, 2008

“Cancer Free at 33, but Weighing a Mastectomy”

The New York Times, Sunday, Sep. 16, 2007

Deborah Lindner, 33, did intensive research as she considered having a preventive mastectomy after a DNA test.

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MCB140, Jan. 23, 2008 The New York Times, Sunday, Sep. 16, 2007

60-80%

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MCB140, Jan. 23, 2008 The New York Times, Sunday, Sep. 16, 2007

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Universal genetic code

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metaphase

prometaphase

Mitosis is the mechanism by which dividing cells partitiontheir chromosomes to produce genetically identical daughters

anaphaseprophase

interphase telophase

Mitosis=M-phase

centrosome

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1n

1n

Sexual reproduction relies on MEIOSIS

2n

haploid

diploid

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Chromosome segregation during meiosis is accomplished through homolog pairing, synapsis, and recombination

Meiotic S-phase

leptotene

gametes

zygotene

pachytene

Meiosis I

Meiosis II

Meiotic prophase

homolog pairing

& synapsis

chromosomecondensation

“crossover”recombination

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A typical human female produces approximately

450 mature eggs over the course of her lifetime.

Eggs are big cells, requiring a serious investment of energy.

A typical human male produces about 60 million mature sperm per milliliter (cm3) of ejaculate.

(In 1940 it was 113 million)

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recombinant

parental

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mcb 142/icb 163, fall 2008 © abby dernburg

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