massbio & the massachusetts biopharma cluster
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MassBio & the Massachusetts BioPharma Cluster. About MassBio. About MassBio. Our Mission: Foster a positive environment that enables each biotechnology company to achieve its full potential, making Massachusetts a world center for biotechnology. About MassBio. - PowerPoint PPT PresentationTRANSCRIPT
MassBio & the Massachusetts BioPharma Cluster
2
About MassBio
Our Mission: Foster a positive environment that enables each biotechnology company to achieve its full potential, making Massachusetts a world center for biotechnology.
About MassBio
About MassBioMassBio represents nearly 620 biopharma companies, service providers, academic institutions, hospitals, patient organizations, foreign agencies and other industry stakeholders.
The 410+ biopharma members are engaged in a wide spectrum of research & development in life sciences.
4,100 attendees
Savings from 20-80% on everything from lab gases, lab equipment, supplies…
MassBioEd Courses,MassBio Committee Meetings
PurchasingConsortium
Networking & Visibility
Annual EventsProfessionalDevelopment
MassBioEdFoundation
EconomicDevelopment
Policy
MassBioMembership
PurchasingConsortium
Networking & Visibility
Annual EventsProfessionalDevelopment
MassBioEdFoundation
EconomicDevelopment
State & FederalPolicy
MassBioMembership
90+ member meetings,
Savings from 20 % on everything from lab gases, lab equipment, supplies…
MassBioEd Courses,MassBio Committee Meetings
PurchasingConsortium
Networking & Visibility
Annual EventsProfessionalDevelopment
MassBioEdFoundation
EconomicDevelopment
Policy
MassBioMembership
PurchasingConsortium
Networking & Visibility
Annual EventsProfessionalDevelopment
MassBioEdFoundation
EconomicDevelopment
State & FederalPolicy
MassBio
BioReadyTM Communities Campaign
Innovation ServicesMassCONNECT
Pharma Days• Investment• Mentoring• Partnering
(March 2011)
Attleboro
Billerica
Brockton
Chicopee
Northampton
Tewksbury
Watertown
Westfield
Fall River
Chelsea
Dedham
Lynn
Newburyport
Reading
Easthampton
BurlingtonEverett
Franklin
GardnerGreenfield
Holliston
Lawrence
NorthbridgeRandolph
Salem
Sturbridge
Andover
Bedford
Beverly
Boston
Cambridge
Canton
Devens
Framingham
Grafton
Haverhill
Lexington
North Andover
Springfield
Taunton
Tri-Town (Southfield)
Waltham
Worcester
Platinum
Gold
Silver
Bronze
West Bridgewater
Marlborough
Chelmsford
Newton
Lowell
Hatfield
Norfolk
Somerville
LeominsterGloucester
Dracut
New Bedford
Pittsfield
Fitchburg
Holyoke
Mansfield
Quincy
Plymouth
Westboro
Hopkinton
Uxbridge
(March 2011)
Attleboro
Billerica
Brockton
Chicopee
Northampton
Tewksbury
Watertown
Westfield
Fall River
Chelsea
Dedham
Lynn
Newburyport
Reading
Easthampton
BurlingtonEverett
Franklin
GardnerGreenfield
Holliston
Lawrence
NorthbridgeRandolph
Salem
Sturbridge
Andover
Bedford
Beverly
Boston
Cambridge
Canton
Devens
Framingham
Grafton
Haverhill
Lexington
North Andover
Springfield
Taunton
Tri-Town (Southfield)
Waltham
Worcester
Platinum
Gold
Silver
Bronze
West Bridgewater
Marlborough
Chelmsford
Newton
Lowell
Hatfield
Norfolk
Somerville
LeominsterGloucester
Dracut
New Bedford
Pittsfield
Fitchburg
Holyoke
Mansfield
Quincy
Plymouth
Westboro
Hopkinton
Uxbridge
BioReadyCommunitiesCampaign
MassBio Services
5
Savings
MassBio negotiates a broad-based collection of contracts and services on behalf of
member companies resulting in the most competitive pricing, large volume rebate
incentives and specialized customer service
6
Access to the Network
Meet new people, learn about trends in the industry, & develop relationships with potential partners at our Forums.
Adventures in Biotech: The Series! The Billion Dollar Molecule Revisited Sex, Drugs & Rock & Roll: The story of
Viagra The Use of Social Media in FDA Regulated
Business: Impact on Patient Recruitment, Product Marketing & Regulatory Compliance
Catalyzing Innovation – The Critical Success Factors for Pharma-Academia Collaboration
Everything You Wanted to Know About Protocol Violations but were Afraid to Ask
7
Access to the Network
Connect with people you have to know & increase your visibility.
Annual Events Open Houses Supplier Series Trade Shows Policy Breakfast Annual Golf Classic
Members-Only Resources
HRonline KnowledgeBase Careers Portal Member News Calendar of Events
8
Business Development
Find your next partner, collaborate, and accelerate innovation.
• Annual Meeting: Don’t miss our signature scientific event for dynamic keynote presentations, panel discussions, interactive working sessions, poster presentations & extensive networking opportunities (April 3-4, 2014)
• MA CRO CMO Symposium: Now in its third year, the Massachusetts CRO/CMO Symposium shines a spotlight on the strength and success of the CRO and CMO communities in the Commonwealth. (May 5, 2014)
• BioPharm America: Attend this annual parterning conference & utilize partneringONE (September 2014)
Innovation ServicesPharma Days
10
Innovation Services MassCONNECT
About MassBio
Innovation Services
Business Development
Access to the Network
Savings
Advocacy
Get Started
Accelerate early stage innovationIn depth gap analysis of the business model
De-risk opportunitiesDefine market needs
Create Connections within the industry
Bio/pharma networksVC and other funding networks
Collaborate with other accelerators and incubators
Strong network to identify and source start-upsReferrals to and from other accelerators
MassCONNECT mentoring model adopted by BayBio & Indiana Bio
MassCONNECT
MassCONNECT
MassChallenge
MA Tech Transfer
Center
Harvard
LabCentral
Tufts Medical Center
University of Massachusetts
MA Research Hospitals
SoPE
12
Innovation Services MassCONNECT Cycle I 2014
About MassBio
Innovation Services
Business Development
Access to the Network
Savings
Advocacy
Get Started
Aldatu Biosciences
Point of care diagnostic for HIV drug resistance
Resilience Pharma
Novel molecular pathway underlying PTSD
MGH NewCO.
Small molecule therapeutic for VHL disease
GlucoWise
Non-invasive glucometer for Diabetics
Aldatu and Resilience semi-finalists in OneStart
GlucoWise winner MIT/Sloan Building Global Innovators
13
Advocacy
Policy: We are the voice of the industry on Beacon Hill & Capitol Hill.
Economic Development: We help members with:
Lab & office space Tax incentives Grants
Workforce Development: We work with our sister organization, MassBioEd on preparing the workforce and filling the pipeline.
About MassBio
Innovation Services
Business Development
Access to the Network
Savings
Advocacy
Get Started
MassBioEconomic Development
&Global Affairs
Promoting the Massachusetts Cluster
Assisting Companieslocate and grow in MA
Industry Data & Analysis
Massachusetts Biotechnology Employment, 2001-2008*
10,000
15,000
20,000
25,000
30,000
35,000
40,000
45,000
50,000
2001 2002 2003 2004 2005 2006 2007 2008
42.6%Growth
Since2001
• Marketing materials• Trade missions/BIO
• Coordination with state agencies
• BioLeads Meetings• Guidance on incentives
• Case management• 50+ active leads on average
Competitiveness
(October 2009)
Attleboro
Billerica
Brockton
Chicopee
Northampton
Tewksbury
Watertown
Westfield
Fall River
Chelsea
Dedham
Lynn
Newburyport
Reading
Easthampton
BurlingtonEverett
Franklin
GardnerGreenfield
Holliston
Lawrence
NorthbridgeRandolph
Salem
Sturbridge
Andover
Bedford
Beverly
Boston
Cambridge
Canton
Devens
Framingham
Grafton
Haverhill
Lexington
North Andover
Springfield
Taunton
Tri-Town (Southfield)
WalthamWorcester
Platinum
Gold
Silver
Bronze
West Bridgewater
Marlborough
Chelmsford
Newton
Lowell
Hatfield
Norfolk
Somerville
LeominsterGloucester
Dracut
New Bedford
Pittsfield
Fitchburg
Holyoke
Mansfield
(October 2009)
Attleboro
Billerica
Brockton
Chicopee
Northampton
Tewksbury
Watertown
Westfield
Fall River
Chelsea
Dedham
Lynn
Newburyport
Reading
Easthampton
BurlingtonEverett
Franklin
GardnerGreenfield
Holliston
Lawrence
NorthbridgeRandolph
Salem
Sturbridge
Andover
Bedford
Beverly
Boston
Cambridge
Canton
Devens
Framingham
Grafton
Haverhill
Lexington
North Andover
Springfield
Taunton
Tri-Town (Southfield)
WalthamWorcester
Platinum
Gold
Silver
Bronze
West Bridgewater
Marlborough
Chelmsford
Newton
Lowell
Hatfield
Norfolk
Somerville
LeominsterGloucester
Dracut
New Bedford
Pittsfield
Fitchburg
Holyoke
Mansfield
• EDAG Initiatives• BioReady TM Communities
Global Relationships
Advocacy Economic Development & Global Affairs
MassBio assists the growth of the biotechnology industry in Massachusetts by:
* pursuing strategies to maintain/improve the competitiveness of the cluster; and
* providing direct services to biotech companies considering entry to or expansion in Massachusetts.
• 17 Foreign agency members• Host 20 delegations annually
• Annual Industry Snapshot• Industry data for members
MassBio Leading Job Listings as % of Total Listings
0.0%
2.0%
4.0%
6.0%
8.0%
10.0%
12.0%
Biochem
istry
Biology
Chem
ist
Clinica
l
Drug D
evelo
pmen
t
Drug D
iscov
eryIS
/IT
Manu
factu
ring
Pre-C
linica
l
Proce
ss D
evelopm
ent
Quality A
ssur
ance
Quality C
ontrol
Regulato
ry
Researc
h
Feb. 08
Sept. 08
Feb. 09
Sept. 09
About MassBio
Innovation Services
Business Development
Access to the Network
Savings
Advocacy
Get Started
430+Biotech
Companies
122Colleges &Universities
Top 5NIH fundedResearchHospitals
1stin
Venture Capital & SBIR funds
per worker
1stin
Education Level of
workforce
550Biopharma
Companies
122Colleges &Universities
9 of the Top 18NIH funded
Research
Hospitals
1stin
Venture Capital & federal research
funds per worker
1stin
Education Level of
Workforce (US)
Why Massachusetts?
SupportiveLocal, State Government
Life Sciences InitiativeBiotech Caucus
The $1 Billion Massachusetts Life Sciences Initiative – Enacted in 2008
• 10 years• $1 billionInvestment$5
00 m
illio
n C
apita
l
Fund
$250 million
Tax Incentive Program
$250m Investment Fund (subject to appropriation)
Over time, the industry demonstrated its value, commitment to the region, and promise for the future . . . and state government responded.
III. History
Kendall Square, 1960
Kendall Square, 1970
60%$564 million
Beth Israel Deaconess $118,785,811
Dana Farber Cancer Institute $115,844,948
Children’s Hospital Boston $126,812,298
Brigham and Women’s $315,919,592
Harvard Medical School $200,413,466
Harvard School of Public Health$120,611,357
2013 NIH Research Funding - Longwood Medical Area - Boston
2013 World Series Champions
1980
1985
2006
Double helix of DNA explained by Watson & Crick
1978
1953
Biogen founded
U.S. Supreme Court approves patenting of recombinant life forms,Passage of Bayh-Dole Act
2000
Map of the human genome is completed
2002
Novartis locates Global Research HQ in Cambridge, MA
2008 $1 B Massachusetts Life Sciences Initiative enacted
BMS chooses to build $1b facility in Devens, MA
Genzyme founded 1981
MassBio becomes the 1st biotechnology industry association
2003
MassBio issues Biotech 2010 Report
1980
1985
2006
Double helix of DNA explained by Watson & Crick
1978
1953
Biogen founded
U.S. Supreme Court approves patenting of recombinant life forms,Passage of Bayh-Dole Act
2000
Map of the human genome is completed
2002
Novartis locates Global Research HQ in Cambridge, MA
2008 $1 B Massachusetts Life Sciences Initiative enacted
BMS chooses to build $1b facility in Devens, MA
Genzyme founded 1981
MassBio becomes the 1st biotechnology industry association
2003
MassBio issues Biotech 2010 Report
Massachusetts Biotech TimelineIndustry History
Cluster AnalysisCONFIDENTIAL — November 2013 23
— DRAFT —
Experienced Leadership: Network Effect in Industry
Note: Representative sample of previous Genzyme employees with CXO title at companies joined after Genzyme. 43 companies excluding Genzyme.
Source: Health Advances analysis, LinkedIn.
Aldexa Therapeutics
FFE Therapeutics
Novavax
Neuron Systems
OvaScience
Red Sky Partners
Declion Holdings
Antigenetics
Thrombolytic Science
International
Intercell
Columbia Laboratories
Link Medical Group
GTC Biothera-peutics
Predictive Biosciences
Verastem
Genzyme
Hydra Biosciences
Hyperion Therapeutics
Five Prime Therapeutics
PureTech Ventures
Exact Sciences
Corp
Peptimmune
Procept
Aronex
Gallus Biopharma-
ceuticals
PathoGenetix
OXiGENE
TetraLogicViscus Biologics
Proteon Therapeutics
bluebird bio
CubistGlycoSolutions
Flatley Discovery LabSarepta
Ocular TherapeutixAbazyme
CandelarEVO Biologics
CatabasisZyngenia
1st 2nd 3rd 4thCXO Position after Genzyme
Talent
Experienced Leadership : Non-profit Research
AcusphereAIRArsenalBIND BiosciencesBlend TherapeuticsEcho TherapeuticsEnzytech (Acq. by Alkermes)Gecko BiomedicaInVivo TherapeuticsKalaLiving ProofMicrochipsModernaMomentaPixarBioPervasisPulmatrixSelecta BiosciencesSeventh SenseSQZ BiotechTarisTransformT2
CompanyCreation
http://www.polarispartners.com/about/strategy/repeat-entrepreneurs/
Networks: Entrepreneurs
Bind Therapeutics Selecta Biosciences Blend Therapeutics
Associate ProfessorHarvard Medical School
Director, Laboratory of Nanomedicine and Biomaterials,Brigham & Women’s Hospital
Omid Farokhzad, M.D.