maryam-jalali-conference-report€¦ · web viewit was fascinating to see the wide applications of...

2
The 9th European Zebrafish Meeting (EZM) 2015, Oslo, Norway The 9th European Zebrafish Meeting (EZM) was held from the 28th of June to the 2 nd of July 2015. It is a biannual meeting that is attended by zebrafish scientists from all over the world who gather together to share and discuss their research. The 2015 meeting was held in Oslo Norway. This was a very well organized meeting. Everything from registration to the planning of talks and poster sessions and the social events were extremely well arranged. The morning sessions began with talks by invited plenary speakers who work in different areas of research and use the zebrafish as an animal model to carry out their research work. It was fascinating to see the wide applications of the zebrafish as a vertebrate animal model in studies involving cancer, regeneration, morphogenesis, neurobiology and development. It was exciting to meet the eminent people in the field of hematopoiesis and to hear their talks and presentations. I attended this meeting with my supervisor, Dr. Martin Gering. I presented a poster that displayed the data I have generated during my PhD as well as some of the work that is done in our lab. Making use of a novel zebrafish gene trap line, the qmc551 line, our lab focuses on hematopoiesis (blood formation) in the zebrafish. In this line the first blood forming endothelial cells with in the ventral wall of the dorsal aorta (vDA) i.e. hemogenic endothelial cells are labeled with a green fluorescent protein (GFP). These cells give rise to the early hematopoietic (blood) stem cells, as they undergo an endothelial to hematopoietic transition and join circulation via the vein. Later these hematopoietic cells seed the caudal hematopoietic tissue (CHT), which is the transitory site of hematopoiesis in the zebrafish embryo. From here the cells migrate to the thymus and kidney, which are the larval and adult sites of hematopoiesis in the fish. I have done a lot of confocal work using this line to study cell behavior and would like to thank Dr. Tim Self and his group from the department of Cell Signalling. Dr. Chris Moore the post doc in our lab has isolated and sorted the GFP+ cells from the early qmc551 embryos, using Fluorescent Activated Cell Sorting. The transcriptome of these cells has been analysed and Chris has found some interesting genes that are specifically expressed in cells within in the vDA, the CHT and the thymus. I presented the data generated on the qmc551 line and I felt honored to be representing my Lab at this high profile platform and the work we do here in the Gering Lab, at the University of Nottingham. It was really nice to see that many people at the conference came up to my poster to have a chat with me and expressed their interest in our work. Listening to many of the talks presented at this conference by both plenary

Upload: others

Post on 06-Jun-2020

2 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: Maryam-Jalali-conference-report€¦ · Web viewIt was fascinating to see the wide applications of the zebrafish as a vertebrate animal model in studies involving cancer, regeneration,

The 9th European Zebrafish Meeting (EZM) 2015, Oslo, Norway

The 9th European Zebrafish Meeting (EZM) was held from the 28th of June to the 2nd of July 2015. It is a biannual meeting that is attended by zebrafish scientists from all over the world who gather together to share and discuss their research. The 2015 meeting was held in Oslo Norway. This was a very well organized meeting. Everything from registration to the planning of talks and poster sessions and the social events were extremely well arranged.

The morning sessions began with talks by invited plenary speakers who work in different areas of research and use the zebrafish as an animal model to carry out their research work. It was fascinating to see the wide applications of the zebrafish as a vertebrate animal model in studies involving cancer, regeneration, morphogenesis, neurobiology and development. It was exciting to meet the eminent people in the field of hematopoiesis and to hear their talks and presentations.

I attended this meeting with my supervisor, Dr. Martin Gering. I presented a poster that displayed the data I have generated during my PhD as well as some of the work that is done in our lab. Making use of a novel zebrafish gene trap line, the qmc551 line, our lab focuses on hematopoiesis (blood formation) in the zebrafish. In this line the first blood forming endothelial cells with in the ventral wall of the dorsal aorta (vDA) i.e. hemogenic endothelial cells are labeled with a green fluorescent protein (GFP). These cells give rise to the early hematopoietic (blood) stem cells, as they undergo an endothelial to hematopoietic transition and join circulation via the vein. Later these hematopoietic cells seed the caudal hematopoietic tissue (CHT), which is the transitory site of hematopoiesis in the zebrafish embryo. From here the cells migrate to the thymus and kidney, which are the larval and adult sites of hematopoiesis in the fish. I have done a lot of confocal work using this line to study cell behavior and would like to thank Dr. Tim Self and his group from the department of Cell Signalling. Dr. Chris Moore the post doc in our lab has isolated and sorted the GFP+ cells from the early qmc551 embryos, using Fluorescent Activated Cell Sorting. The transcriptome of these cells has been analysed and Chris has found some interesting genes that are specifically expressed in cells within in the vDA, the CHT and the thymus. I presented the data generated on the qmc551 line and I felt honored to be representing my Lab at this high profile platform and the work we do here in the Gering Lab, at the University of Nottingham. It was really nice to see that many people at the conference came up to my poster to have a chat with me and expressed their interest in our work.

Listening to many of the talks presented at this conference by both plenary speakers and students from eminent universities around the world made me realize that we are carrying out similar experiments. This made me think about how fortunate I am to be a part of such a prestigious university and lab that does research which is at power with other big labs around the world. The highlight of the conference was the formal dinner on the last night of the conference that was held in the famous Opera House of Oslo City. This formal night commenced with a well-composed zebrafish jingle that we all sang together!!! Besides attending the conference it was a pleasure to visit Norway, with beautiful sites of tourist attractions.

I would like to take this opportunity to thank the School of Life Sciences and The Carr Scholarship Fund for funding my travel and giving me this chance to attend this high profile conference.

Maryam JalaliPhD Student Supervised by Dr Martin Gering

Page 2: Maryam-Jalali-conference-report€¦ · Web viewIt was fascinating to see the wide applications of the zebrafish as a vertebrate animal model in studies involving cancer, regeneration,