Mapping Your Future:Mapping Your Future:

Careers in Careers in BiomanufacturingBiomanufacturing

Winnell NewmanWinnell NewmanManager, Student Programs at Manager, Student Programs at BTECBTECGolden LEAF Biomanufacturing Training and Education CenterGolden LEAF Biomanufacturing Training and Education Center NC State UniversityNC State University winnell_newman@ncsu.edu (919) 515-0213 (919) 515-0213

www.btec.ncsu.edu

The Golden LEAF BTEC: The The Golden LEAF BTEC: The Promise and State of DeliveryPromise and State of Delivery

NCBioImpactNCBioImpact http://www.ncbioimpact.com/ http://www.ncbioimpact.com/

Industry informed Training and Education

Nearly 19,000 people work in biomanufacturing-related jobs in North Carolina. To train residents for these high-skill, Nearly 19,000 people work in biomanufacturing-related jobs in North Carolina. To train residents for these high-skill, high-paying jobs, the state has put together a comprehensive and unique training program to recruit, train and retain high-paying jobs, the state has put together a comprehensive and unique training program to recruit, train and retain

workers. workers. The The North Carolina Biotechnology Center has joined the has joined the North Carolina Biosciences Organization, the North Carolina , the North Carolina

Community College System, the University of North Carolina System to create and implement this program.Community College System, the University of North Carolina System to create and implement this program.The coordinated effort, called NCBioImpactThe coordinated effort, called NCBioImpact

Consortium PartnersConsortium Partners

Industry

Who Are We?Who Are We?• Team – Professors and StaffTeam – Professors and Staff

• 85,000 ft85,000 ft22 Facility. “The Golden LEAF Facility. “The Golden LEAF Biomanufacturing Training and Education Center - Biomanufacturing Training and Education Center - BTEC ”BTEC ”• Hands on TrainingHands on Training

• By Government - For IndustryBy Government - For Industry• Advisory Board comprised of Industry and Academic Advisory Board comprised of Industry and Academic

PartnersPartners

• Grow Biotech base in North CarolinaGrow Biotech base in North Carolina

• First of a kind facility in USAFirst of a kind facility in USA

The PromiseThe PromiseThe Golden LEAF Biomanufacturing Training and Education Center (BTEC) on the Centennial Campus at North Carolina State University provides a unique pilot-scale, industry-informed, cGMP environment critical to developing

a workforce proficient in the skills needed in the biomanufacturing industry. This educational investment will fuel prosperity by positioning North Carolina as a global leader in bioprocess education and biomanufacturing workforce development.

The PromiseThe PromiseThe Biomanufacturing Training and Education Center (BTEC) on the Centennial Campus at North Carolina State University provides a unique pilot-scale, industry-informed, cGMP environment critical to developing

a workforce proficient in the skills needed in the biomanufacturing industry. This educational investment will fuel prosperity by positioning North Carolina as a global leader in bioprocess education and biomanufacturing workforce development.

(2) Facility(1)Relevant

(3)Curriculum(4)Student-Industry

Relevant: BTEC OrganizationRelevant: BTEC Organization

NCSU 16/38 = 42%

Other Academia = 4/38 = 11%

Industry = 18/38 = 47%

Relevant: BTEC Advisory BoardRelevant: BTEC Advisory BoardIndustry

• Biogen-Idec• Biolex• Cardinal Health• Diosynth• Eisai• GSK• KBI BioPharma• Merck• Novartis• Novo-Nordisk• Novozymes• PhaseBio• Talecris Biotherapeutics• Wyeth NCCCS

• System Office• BioNetwork

NCBC

Suppliers• ABB• Sartorius

NCBIO/BMF

Golden LEAF Foundation

BRITE

NCSU• Provost• VC, Finance & Business• VC, Research & Grad Studies• Dept Head, Genetics

(2)Facility(2)Facility

State-of-the Art FacilityState-of-the Art FacilityOne-of-a-kind in USAOne-of-a-kind in USAright here at NCSU in Raleighright here at NCSU in Raleigh

www.btec.ncsu.eduwww.btec.ncsu.edu

What is Biotechnology?What is Biotechnology?

Technologies that use Technologies that use cellscells or or biomoleculesbiomolecules to solve problems to solve problems and make useful productsand make useful products

5 Largest challenges to Human 5 Largest challenges to Human Society – biotechnology involved Society – biotechnology involved

in solving themin solving themSo what good is Biotechnology?

A Typical ProcessA Typical Process

Gene in cells grow a few cellsGene in cells grow a few cells grow a LOT of cells in bioreactorgrow a LOT of cells in bioreactor spin down and break open spin down and break open

GFP – our teaching tool purify the product GFP – our teaching tool purify the product use special chemistry on beads filter / separate use special chemistry on beads filter / separate Green Fluorescent ProteinGreen Fluorescent Protein which are packed in these housings materials which are packed in these housings materials(from Jellyfish)(from Jellyfish)

cGMP – Examples of JobscGMP – Examples of Jobs

• StaffStaff

• Education/TrainingEducation/Training

• StructureStructure

• ProcessProcess

• ValidatedValidated

• CleaningCleaning

• TestingTesting

• ReleaseRelease

•FacilityFacility• DesignDesign

• FlowFlow

• CleaningCleaning

• ChangeoverChangeover

• ValidationValidation

Pictures Courtesy Diosynth Biotechnology

ResourcesResourcesWeb links with great information on:

Education needed Job Titles / Pay rangesBiotech Guide Companies in North CarolinaNorth Carolina Biotechnology Center www.ncbiotech.orghttp://www.ncbiotech.org/resource_center/jobs_in_nc/window_on_the_workplace/http://www.ncbiotech.org/news_and_events/news_releases/guidebook.htmlhttp://ncbiotech.org/resource_center/biomanufacturing.htmlhttp://ncbiotech.org/ncbio/ncindustry/directories/companies/printable_company_list.html

NCSU Office of Pre-College (efforts) http://www.fis.ncsu.edu/coop%5Fed/precollege/index.html

BiomanufacturingIt’s a growing industry in North Carolina … … which needs an educated-trained workforce

MORE …. ResourcesMORE …. Resources

Web links to videos :

See, hear, learn from real people in jobs in biotechnology

http://aboutbioscience.org/Videos - www.aboutbioscience.org/bc_title.html

http://www.ncabr.org/The mission of the North Carolina Association for Biomedical Research is to promote public understanding and support for bioscience research.

Biomanufacturing

It’s a growing industry in North Carolina … … which needs an educated-trained workforce

Biotechnology is BoomingBiotechnology is BoomingGrowth in Global Biotechnology, 2005-2006

Public company Data 2006 2005 Change

Revenues (US $m) 73,478 64,213 14.0%

R&D expenses (US $m) 27,782 20,934 33.0%

Net Loss (US $m) 5,446 4,039 35.0%

Number of employees 190,500 173,110 10.0%

Number of companies      

Public 710 673 5.0%

Private 4,275 4,263 0.3%

US Biotechnology, 2005-2006

Industry Total 2006 2005 Change

Revenues (US $m) 48 42 13.4%

R&D expenses (US $m) 27 21 30.2%

Net Loss (US $m) 6 4 58.5%

Number of employees 180,800 170,500 6.0%

Number of companies      

Public 336 331 5.0%

Private 1,116 1,144 -1.6%

Source: Ernst & Young: “Beyond Borders: the Global Biotechnology Report 2007”

Recruit Support Place• NCSU Students• NCCCS Transfers• Industry Professionals• K-12

Industry- Ready

Graduates

• Career Fairs• Teacher Workshops• Recruiting Trips• Promotional Literature• SCIBLS• Tours

• One-on-one• ISPE Student Chapter• Student Projects• Presentation Skills• Internships

• Co-op/Internship Options• Industry Information• Job Fairs• Resume Assistance• Interview Practice• Network Support

Student CoordinationStudent Coordination

Creating Value for Students and Industry

Assist HS students to make informed Choices

K-12: 6-InitiativesK-12: 6-Initiatives

TodayTomorrow – with your help

Plan Ask for Help Success

• Ask your Family• Ask your Teachers• Ask for Trips to companies• Ask for Tours of companies• Ask companies if they will support activities at your school

• Seek out Co-op / Internship Options• Web search for Industry Information• Learn about what Job Fairs are• Practice writing your Resume• Practice Interviews / discussions with people• Build your Network

Ask for HelpAsk for HelpLots of people will help, if you are focused and ASK !