many faces of wound care limb salvage.pdf · 2017-09-05 · spectrum -539 pt. empirical antibiotic...

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Many Faces of Wound Care Bridging Antibiotics, Biologics, and Surgical Reconstruction Dr. Javan S. Bass, FACFAS Metro Foot & Ankle Centers, PC Georgia Podiatric Association Board of Directors

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Page 1: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Many Faces of Wound CareBridging Antibiotics, Biologics, and Surgical

Reconstruction

Dr. Javan S. Bass, FACFAS

Metro Foot & Ankle Centers, PC

Georgia Podiatric Association Board of Directors

Page 2: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

No disclosures

Page 3: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Stakes are high

Page 4: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

BKA Complications

Wound Dehiscence

Stump Neuroma

Phantom Limb Pain

Prosthetic Complication

Page 5: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Guidelines

UK Hospital – multidisciplinary approach

- reduced total amputation 40%

- reduced major amputation 62% over 11yr

Lost Financial Support = amputation rates

rose

Regained Support = amputation rates fell

Krishnan et al Diabetes Care 2008

Page 6: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Biologics

Antibiotic Surgery

Page 7: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Antibiotics

Resistance

????????

-Spectrum

-Course

-Diagnosis

Page 8: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Spectrum

-539 pt. Empirical antibiotic therapy inadequate 22% (121)

-168 pt. Adjusted, antibiotic therapy inadequate 27% (46)

-Main Reason, broad spectrum (24% of original, 52% of

adjusted)

Metler et al BMC ID 2007

Page 9: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Course

-Uncomplicated cellulitis, 5 day as effective as 10

day course Levofloxacin

-Composite scores for cellulitis, subjective pain, and

swelling comparable between 5 day vs. 10 day course

Hepburn MJ et al Arch Intern Med 2004

Page 10: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Diagnosis

-69 pt., poor concordance between wound culture

swabs and percutaneous bone biopsies (22.5%)

Senneville et al CID 2006

Page 11: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Biologics

Antibiotic Surgery

Page 12: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Biologics

Amniox

-Cryopreserved Human

Umbilical Cord and Amniotic

Membrane

Grafix-Cryopreserved placental

membrane comprised of an

extracellular matrix (ECM)

Page 13: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

1st Clinic Visit

42 Y/O

Diabetic

PVD

HTN

Staph Infection

BKA

Recommendation

Page 14: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

2 Applications 7 Weeks

Limited

Debridement

Page 15: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

2 Applications 8.5Weeks

Non-Compliance

Page 16: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

3 Applications 11 Weeks

Page 17: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

4 Applications 15 Weeks

Non-Compliance

Page 18: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

4 Applications 17 Weeks

Page 19: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

20 Weeks

Page 20: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%
Page 21: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

After HBO for 8 weeks

29 Y/O

Paraplegic

Smoker

BKA

Recommendation

Page 22: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%
Page 23: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

2cnd Application Week 6

Page 24: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

3rd Application Week 9

Pressure Kills

Page 25: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

3rd Application Week 30

Page 26: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Week 33

When Possible

don’t touch!!

Page 27: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Week 36

Page 28: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Recap

Deep Sub Q -- Skin

Resist the urge!!!

Pressure Kills!!!!!

Page 29: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Biologics

Antibiotic Surgery

Page 30: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Pressure and Charcot

30 Y/O AA Female

Uncontrolled DM

Wound > 1 year

Staph Infection

BKA

Recommendation

Page 31: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%
Page 32: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Surgical Recon

Page 33: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Treating Pt. vs X-ray

Page 34: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%
Page 35: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%
Page 36: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%
Page 37: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%
Page 38: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Goals

Stave off infx

Heal the wound

Clear the pt.

Keep the leg

Send patient

Page 39: Many Faces of Wound Care Limb Salvage.pdf · 2017-09-05 · Spectrum -539 pt. Empirical antibiotic therapy inadequate 22% (121)-168 pt. Adjusted, antibiotic therapy inadequate 27%

Metro Foot and Ankle Centers, P.C

Metrofootanklepc.com

[email protected]

[email protected]

770-484-9599