OOOO ABSTRACTS

Volume 117, Number 2 Abstracts e171

PE-201 - MANAGEMENT OF CHERUBISM WITHCALCITONIN AND TRIAMCINOLONE ACETONIDE:CLINICALCASEREPORT. VANESSA CHIDIAC JORNADA,MARIA NOEL MARZANO RODRIGUES PETRUZZI, LILIANESOARES YURGEL, FERNANDA GONÇALVES SALUM,MARIA ANTONIA ZANCANARO DE FIGUEIREDO, KARENCHERUBINI. PONTIFÍCIA UNIVERSIDADE CATÓLICADO RIO GRANDE DO SUL.

Cherubism is a benign disorder characterized by “raised-to-heaven” eyes, painless jawbone enlargement, abnormal dentition,and intra-osseous central giant cell granuloma-like lesions. Sincethe disease presents a tendency toward spontaneous remission,treatment need raises controversy. However, aggressive lesionsmight require clinical intervention. Young woman, 17, wasreferred to the department of stomatology with dental impaction,agenesis, and tooth mobility associated with swelling in themental region plus buccal cortical bone thinning. Clin-icohematological, radiographic, and histopathological findingscontributed to the diagnosis of cherubism. To prevent toothloosening and pathological bone fracture, the patient has beentreated for 6 months with calcitonin (200 IU) every other day vianasal passage and intralesional injections of triamcinolone ace-tonide (20 mg/ml) diluted with lidocaine (10 mg/ml). Despite theunpredictable prognosis, favorable results are being achieved.The proposed management is well tolerated and should beconsidered as a noninvasive treatment alternative for cherubismlesions.

PE-202 - MANAGEMENT OF DENTAL PATIENTS USINGBISPHOSPHONATES: CASEREPORT. INÁCIO LIMA SILVAAGUIAR, ANTONIO FERNANDO PEREIRA FALCÃO,VIVIANE ALMEIDA SARMENTO, PATRICIA LEITE RIBEIROLAMBERTI, DAVI SILVA CARVALHO CURI, ANDRÉ LUCASD’ALMEIDA LYRIO DOS SANTOS, THAMIRES SILVASOUZA. UFBA.

Bisphosphonates have an affinity for bone tissue and areused in the treatment of bone disorders. However, they havebeen associated with osteonecrosis of the jaws, dentists shouldbe aware of how to prevent this disease. Man, 44, was diagnosedwith multiple myeloma for which he was undergoing chemo-therapy. During therapy, he developed hypercalcemia afterreceiving a dose of pamidronate. He was referred for dentaltreatment before continuing the treatment. Studies have shownthat cases of osteonecrosis are directly associated with dentalprocedures, but the causes remain unclear. Because of themorbidity of this condition, performing needed dental treatmentbefore beginning bisphosphonates is essential to reduce potentialsources of infection.

PE-203 - MANDIBULAR FRACTURE-INDUCED OSTEO-RADIONECROSIS. RODRIGO MONTEZANO DA CUNHA,TAIANE BERGUEMAIER DE LIMA, KÍVIA LINHARESFERRAZZO, MÁRCIA RODRIGUES PAYERAS. FRAN-CISCAN UNIVERSITY CENTEReUNIFRA - SANTA MARIA/BRAZIL.

Osteoradionecrosis is the collateral effect of radiotherapyin the head and neck and is of great clinical significance.A case of mandibular fracture-induced osteoradionecrosiswas reported. Man, 52, sought dental care with a history oforal cancer and radiotherapy. Examination revealed extraoral

fistula in the left jaw, limited mouth opening, and an area ofintraoral exposed bone. The clinical diagnosis was osteor-adionecrosis. The panoramic radiograph revealed fracture ofthe left mandibular body. Clindamycin plus daily mouthwashwith chlorhexidine gluconate 0.12% for 15 days was pre-scribed, resulting in the closure of intraoral and extraoralfistulae. The mandibular fracture remains, with the patientawaiting further intervention. We highlight the importance ofintegration between medical and dental teams in preventingand treating side effects of oral cancer therapy with the goal ofavoiding debilitating consequences that affect the quality oflife of these patients.

PE-204 - MANDIBULAR METASTASIS OF DUCTALBREAST CARCINOMA: CASE REPORT. THAYANA KARLAGUERRADOSSANTOS,PATRÍCIAMEIRABENTO,DANIELAPITA DE MELO, DALIANA QUEIROGA CASTRO GOMES,GUSTAVO PINA GODOY, CASSIANO FRANCISCO WEEGENONAKA, POLLIANNA MUNIZ ALVES. UNIVERSITY OFPARAÍBA (UEPB).

Breast cancer is the most common malignant disease inwomen. About 60% of patients with breast cancer haveadvanced disease and develop bone metastases, but these arerare in the maxillofacial region. Woman, 66, complained ofsymptomatic swelling in the left posterior mandible that hadincreased rapidly. Four years previously she was treated forbreast cancer using radiotherapy and chemotherapy. Panoramicradiograph demonstrated radiolucency with cortial bone rupture;scintigraphy showed hyperintense signal in the left posteriormandible. The preliminary diagnosis was osseous metastases.An incisional biopsy was performed, and microscopic exami-nation revealed a malignant neoplasm exhibiting proliferatingatypical and undifferentiated cells. Immunohistochemistry re-sults were positive for estrogen receptor and negative for pro-gesterone receptor and C-erbB2. The definitive diagnosis wasmandibular metastasis of ductal breast carcinoma. This caseshows the essential role dentists play in diagnosing maxillofacialmetastases and possibly prolonging survival and improving thequality of life of patients.

PE-205 - MANDIBULAR ODONTOGENIC MYXOMA:FROM RESECTION TO REHABILITATION: CASE REPORT.ANDERSON DA SILVA MACIEL, BRAULIO CARNEIROJUNIOR, ROBERTO ALMEIDA DE AZEVEDO, VIVIANEALMEIDA SARMENTO. UFBA.

Odontogenic myxoma is a benign tumor but can be locallyaggressive. The mandible is the most often affected site. Myx-oma promotes the painless expansion of cortical bone and candisplace teeth. When small, the tumor may not produce abnor-malities except on radiographic examination, which shows aunilocular or multilocular radiolucency with irregular margins.The defect may contain thin residual bone tissue arranged atright angles to one another, described as a “stepladder pattern.”The treatment of choice to minimize recurrence is extensiveresection, so rehabilitation of patients can be quite challengingfor surgeons. Microvascular reconstruction techniques, osseousfree flaps, and other procedures such as distraction osteogenesis,when associated with osseointegrated implants and prosthetics,allow the recovery of both function and aesthetics. This paperreports a case of a patient diagnosed with myxoma and its oralrehabilitation.