making sense of psychiatry: an insecure profession

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    AN INSECURE PROFESSION

    In my second year of residency at San Antonio I trained in psychiatric

    consultation, providing assessment and treatment to patients who wereidentified as having psychiatric difficulties while hospitalized on other

    medical services. Problem-solving has always been what I enjoy most about

    my job, and the identification and resolution of issues on the consultation

    service challenged me to develop a variety of skills that were not necessarily

    employed in individual treatment.

    At the beginning of the rotation the director of the service, Dr. David

    Fuller, taught us that consultations often arose from the complaints of the

    medical treatment team rather than from the patient. For example, the

    psychiatrist might be consulted to assess a patient for aberrant behavior, but

    eventually find that the appropriate intervention was to provide direction and

    reassurance to the nursing staff in dealing with a patient who just happened

    to have a particularly nasty disposition. Another consultation might require

    the psychiatrist to provide counseling to a particularly intrusive family

    member who was interfering with treatment. Because the initial consultation

    request might be misleading, Dr. Fuller encouraged us to keep an open mind

    regarding the motivation behind the consultation, reminding us that we were

    being asked to intervene because somebody had a problem and needed our

    helpit just might not be the patient. His contention was that There is no

    such thing as an inappropriate consulta maxim that is not entirely true, butnonetheless useful in promoting the maintenance of a positive and helpful

    attitude for nearly all situations.

    My enthusiasm for the work apparently gained me some consideration,

    and I developed a collegial relationship with some of the non-psychiatric

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    physicians. In the course of friendly conversation one revealed to me that

    psychiatrists were commonly referred to as spooksas in, That patients

    weird. Lets get a spook to look at him. I was more amused than upset, but

    immediately knew that it wasnt at all meant to convey respect for myspecialty. On reflection it may have referenced the detachment from real

    medicine that psychiatrists frequently displayed at the time (around 1983,

    when the biological model was just taking root); their tendency to appear and

    disappear on the medical units with little interdisciplinary communication;

    and/or their myriad personal eccentricities (since psychiatrists are generally

    quirkier than other doctors). It may have even hinted at some implicit

    hostility toward psychiatric patients, whose behavioral foibles and self-

    destructive tendencies were not suffered easily by other physicians. At any

    rate, it brought home the fact that within the medical community there were

    many different types of doctorsand then there were psychiatrists.

    Psychiatrys rash embrace of the biological model in the years since then

    has generally been attributed to the considerable financial influence of the

    pharmaceutical industry. Certainly this was a driving force, as its unlikely

    that so many psychiatrists would have changed their clinical thought and

    practice if there wasnt a lot of money at stake. But another contributing

    consideration was psychiatrys abiding status as the red-headed stepchild of

    medical specialties, struggling for a secure sense of its professional identity in

    the midst of realdoctors who are dealing with more tangible clinical

    problems.Time and again psychiatry has responded to this deficit by hitching its

    wagon to half-baked theories, capriciously overreaching its scientific grasp in

    a desperate attempt to validate both its treatment philosophydu jour, and its

    right to stand shoulder to shoulder with other medical specialties. This

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    inconstancy is evident from even a cursory review of its historybut the effort

    required to get at that history is itself confirmatory of psychiatrys low self-

    esteem. When I was in residency a fair amount of the curriculum was

    devoted to the discoveries and theories of past luminaries, particularly thoseof the psychoanalytic movement. Now that the recent swing to the biological

    model has made those figures largely irrelevant, the history of psychiatry has

    been banished for the most part to arcane corners of academic medicineor

    seized upon by its critics in the antipsychiatry movement, who revel in the

    follies that have been perpetrated over the years in the guise of treating

    mental illness.

    The challenge of producing an authoritative and politically neutral

    history of psychiatry has even merited its own book, a scholarly collection of

    essays entitled Discovering the History of Psychiatry (Oxford University

    Press, 1994). In its introductory chapter, editors Roy Porter and Mark Micale

    observe that in no branch of history of science or medicine has there been

    less interpretive consensus. They go on to state:

    From its earliest days, psychiatric medicine has been marked by

    the persistence of competing, if not bitterly opposing, schools.

    Most noticeably, the field since the eighteenth century has been

    convulsed by a deep, dichotomous debate between the somatic

    and mentalist philosophies of mind. Moreover, for professional

    purposes, each generation of practitioners has written a historythat highlights those past ideas and practices that anticipate its

    own formation and consigns to marginal status competing ideas

    and their heritages. In this process, individual figures and texts

    indeed, entire historical periods and bodies of knowledgehave at

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    times been omitted from the historical record. With an intensely

    subjective subject matter, complex multidisciplinary origins, and

    insecure and shifting epistemological base, porous disciplinary

    boundaries, and a sectarian and dialectical dynamic ofdevelopment, it has thus far proved impossible to produce

    anything like an enduring, comprehensive, authoritative history of

    psychiatry.

    The selective suppression of history that is noted here by the authors

    smacks of an Orwellian design to reinforce the current truth and consign

    dissent (and dissenters) to oblivion. However, I doubt that its real purpose is

    to restrain consideration of psychoanalytic theory, since it seems unlikely that

    advocates of the biological model would feel at all imperiled nowadays. (After

    all, they have Prozac and managed care on their side; the analysts dont.)

    Rather I believe that contemporary psychiatrists are embarrassed by the

    theories that once held sway in psychiatryand threatened by the larger

    questions they raise about the durability of truth in our line of work.

    So what exactly is it that psychiatrists are trying to hide? Well,

    fortunately there is at least one comprehensive (yet readable) overview

    availableA History of Psychiatry: From the Era of the Asylum to the Age of

    Prozac (Wiley, 1997), by noted medical historian Edward Shorterand I have

    cribbed from it shamelessly. Mr. Shorter does a good job of recounting the

    many twists and turns taken by psychiatry over the centuries, and I highlyrecommend the book to anyone who needs more thorough documentation of

    just howundisciplined this alleged discipline has been in the past.

    But before we begin to ponder psychiatrys many sins against science,

    lets first consider the peculiar challenges it faces as a medical specialty. Its

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    main anatomical focus is the brainan organ entirely encased in bone.

    Underneath the bone are layers of fibrous tissue and fluid that cushion the

    brain, all of which are vulnerable to infection if intruded upon. The brain

    itself is a fabulously complex array of about a hundred billion nerve cells(neurons), each with numerous junctions connecting it to its neighboring

    cells. Cells communicate between each other across these nerve junctions

    (synapses) through the secretion of chemical messengers known as

    neurotransmitters. There are over 100 different neurotransmitter agents

    identified in the human brain, each of which may have either an excitatory or

    inhibitory effect on the postsynaptic cell depending on what kind ofreceptor

    protein it contacts in the cell membrane. The location of this intercellular

    communication is in the synaptic cleft, the microscopic space within the

    junction which is crossed by the neurotransmitter, where the balance of

    neurotransmitters is constantly adjusted by the two cells through the

    processes of release, metabolism, and reuptakewhich in turn are regulated

    by an elaborate feedback network incorporating input from other neurons as

    well. In short the raw circuitry of the brain is microscopic, profuse, and

    unimaginably complex.

    The physiological tasks of brain cells are largely determined by their

    location within the brainand the higher functions associated with thoughts

    and feelings are particularly inscrutable, since they occur within a

    microscopic assemblage of neurons acting in a meticulously coordinated

    fashion. Hence studies of brain cells in vitro (i.e. outside of the body in alaboratory medium) tell us little about their psychiatric function. This leaves

    us with the necessity of studying brain cells in vivo (in the living organism) to

    gain an accurate understanding of their function. But doing so would require

    passing a needle past the skull and through the surrounding nerve tissue,

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    causing irreparable damage to the brain since neurons have little if any

    capacity for regeneration. This makes direct observation of living brain tissue

    ethically unacceptableand even if it wasnt, how many people would give

    informed consent to participate in such a study?The other medical specialties (besides neurology, of course) focus on

    organ systems that are infinitely less complicated than the brain, more

    physically accessible, and able to withstand a needle biopsy without

    irreparable loss of function. Chemical markers associated with these systems

    are typically measurable in the peripheral blood (unlike those of the brain);

    other intrusive diagnostic procedures such as endoscopy are available as well.

    Access to this sort of information allows physicians to be reasonably certain

    whats going on inside the patienta feeling with which any prudent

    psychiatrist would be dreadfully unfamiliar.

    In point of fact, the secrets of the brain constitute a last frontier more

    scientifically daunting than astrophysicswhich, after all, is just the study of a

    bunch of dumb particles that happen to be very far away. Before one even

    contemplates its anatomical and physiological complexities, there is the

    conundrum of its dualitythe brain in the corporeal world, the mind in the

    ethereal. Like astrophysics, neuroscience is an area of study that raises

    existential and spiritual questions, and provokes the sort of controversies that

    are attendant to such concerns. In the realm of medical science the brain

    stands out as a uniquely remote wonder, a bottomless enigma that weve

    barely begun to crack. So lets just acknowledge beforehand the onerousscientific challenge that is confronted by psychiatric researchers.

    This predicament is aggravated by the likelihood that once a psychiatric

    disorder does become treatable, it will be reclassified as a non-psychiatric

    disease. In the 19th Century a large proportion of asylum inmates were

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    diagnosed with general paralysis of the insane (GPI)a psychiatric disease

    characterized by manic symptoms or other behavioral problems, followed

    thereafter by the onset of dementia and progressive paralysis. It was noted

    that this presentation was more frequent in men, especially those withdebauched lifestyles. Eventually this problem was identified as

    neurosyphilis, an advanced stage of syphilis that takes ten years or more to

    manifest itself in infected individuals. Once antibiotic treatments were

    developed it became a medical illness, and thus no longer the concern of

    psychiatrists. Similar paths were followed by epilepsy, the thiamine

    deficiency and hepatic encephalopathy associated with alcoholism,

    Parkinsons disease, Huntingtons chorea, and other neurodegenerative

    diseases. It would seem that we are in part definedas a specialty by our

    ineffectualitysince any disease that can be readily treated becomes someone

    elses responsibility. This sequence of events pretty much dooms us to clinical

    failure, which is a pretty darned demoralizing state of affairs. (No wonder we

    have a complex!)

    Another distinguishing characteristic of psychiatric disorders is that

    they typically present with behavioralsymptomswhich inevitably drags us

    into the murky arena ofwill. Nearly all patients who go to a non-psychiatric

    doctor for a medical complaint are doing so on their own volition, for

    symptoms that are unequivocally imposed on them by disease. Relief of these

    complaints typically entails the administration of medication, but it may also

    call for changes in lifestyle or entry into a rehabilitation regimen, all of whichrequire motivation and compliance on the part of the patient in order to

    ensure efficacy of the treatment. In most cases the complaint that initially

    drove him to seek helppain, fear, or some other sort of discomfortwill

    continue to act as an external motivator, prodding the patient to comply

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    despite his resistance. Sure, the patient may refuse to follow throughbut

    not without persistence of his physical distress, and the knowledge of what he

    ought to be doing to relieve it.

    The motivation to pursue treatment of a psychiatric disorder is rarelythat simple. At one extreme you have patients who are involuntarily

    committed by court order to psychiatric treatmentusually because of

    behaviors that are dangerous to the patient or to others (i.e. risk of suicide or

    assault), though sometimes due to unmanageable behaviors that are

    peculiarly disruptive to society (as I will explore later). Even those who come

    into treatment without such a court order may have other extenuating

    circumstances coercing them into treatment, such as the demands of a

    spouse, job difficulties, or legal concerns (e.g. child custody litigation,

    probation, or a recent arrest)which is often a recipe for treatment failure

    due to their lack of earnest investment in the process. Patients who are

    internally motivated for treatment are often conflicted, struggling with

    feelings of guilt, shame, or fear arising from their need to pursue help, or

    perceived dependency on medications. Those seeking help for depression

    often succumb to the lack of motivation that is associated with that disorder,

    skipping medication doses and/or missing appointmentsor have difficulty

    making the lifestyle changes (e.g. sobriety, diet, personal hygiene) that would

    be beneficial in alleviating their symptoms. Patients struggling with mania

    often chafe when confronting the drudgery of reconstructing their lives, and

    are tempted to stop their meds so they can fly back into the fantasy world oftheir illness. In short, the issue of patientwill arises over and over again in

    the treatment of psychiatric disorders.

    Consequently, psychiatrists regularly struggle to attain the degree of

    authority and trust within the clinical relationship that is necessary to

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    motivate treatment compliancea problem largely unfamiliar to other

    medical specialties. In my first year of residency I spent several months in a

    neurology rotation under the supervision of a rather cocky senior resident.

    Near the end of my rotation I ran into him at a party, where he proceeded tochide me for going into psychiatry since in a few years neurologists will be

    treating all your patients. I fired back, Are you kidding? You guys will

    neverbe able to stand working with patients that dont do what you tell them

    to! Little did I know at the time the enduring truth implied in that drunken

    utterancethat the practice of psychiatry is indeed defined by the patient

    management challenges inherent to treating disorders of behavior.

    With so much to prove to our patients and peers, and a dearth of

    reliable scientific information, psychiatry has time and again compensated for

    the deficiency of its knowledge base by simplymaking shit up. The

    unfathomable nature of our calling conveniently lends itself to grand

    fabricationsand when patients bring us uneasy questions about what were

    doing and how it works, almost any answer seems more satisfactory than I

    dont know. As a consequence psychiatry has been prone to spasms of

    radical reinvention over its history, as one line of pseudoscience is replaced by

    another in a desperate attempt to cover up the gaps in our comprehension.

    As previously noted, two competing schools of thoughtone biological,

    the other psychosocialhave struggled for ideological control of psychiatry

    since its conception. Always the more covetous of medical legitimacy,

    biological proponents have had to vie with the many obstacles that impedestudy of the brain, and make do with the limited technical means available to

    them. In the 18th and 19th centuries speculation on the cause of psychiatric

    disorders was largely focused on anatomy, since most of their information

    came from the study of cadavers. The dearth of hard science invited the

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    ruminations of doctors with large egos but limited clinical qualifications

    such as Theodor Meynert, a notable neuropathologist at the Vienna asylum

    who had the brass to begin lecturing on psychiatry in 1868, even though he

    had no apparent interest in patients, saw little hope in treating them, and byall accounts preferred the company of microscopes and brain sections.

    The resultant theories now seem coarsely simplistic, and often

    childishly wrongheaded. In 1755 Oxford graduate Charles Perry described

    hysteric passion as a common and incapacitating nervous disorder among

    women that was caused by errors and defects in our accretions and

    secretions, and boasted that he was able to treat it with uncommon success

    and effect. Soon afterward French and English psychiatrists were diagnosing

    female patients with nervous vapours which allegedly arose from the uterus,

    and had the power to derange all the functions of the brain according to

    Joseph Daquin in 1787. By 1812 Benjamin Rush (proclaimed the father of

    American psychiatry by the American Psychiatric Association in 1975)

    affirmed that the cause of madness is seated in the blood-vessels of the brain,

    and it depends on the same kind of morbid and irregular actions that

    constitute other arterial diseases. Complete and utter ignorance of basic

    neurophysiology seems to have been no hindrance to the expression of

    authoritative opinion on the subject.

    French psychiatry was dominated in the 19th Century by the charismatic

    presence of Jean-Martin Charcota brilliant neurologist who is credited with

    identifying multiple sclerosis, amyotrophic lateral sclerosis (aka ALS or LouGehrigs disease) , and numerous other neurological disorders. In the 1870s

    he turned his energies to advancing his personal notion of hysteria, an

    assortment of neurotic symptoms that he believed to constitute an inheritable

    disease associated with unidentified changes in nerve tissue. He promoted

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    this concept by performing public lectures, the highlight of which was his

    dramatic demonstration of hysterical symptoms in female subjects that he

    hypnotized on stage. These presentations became a national sensation, and

    led his theories to gain widespread acceptance among psychiatriststhroughout Europeonly to be debunked after his death in 1893.

    An infinitely more regrettable innovation of French psychiatry was the

    concept ofdegeneration. At the time nearly all psychiatrists believed

    psychiatric disorders to be directly inheritable. In 1857 a French physician,

    Benedict-Augustin Morel, proposed that something even more insidious was

    happening in the psychiatrically impaired, advancing the pre-Darwinian

    notion that acquired characteristics (such as alcoholism and moral turpitude)

    could be genetically incorporated and passed on to the next generation. The

    anticipated result would be a steady accumulation of inherent psychiatric,

    constitutional, and even moral dysfunction in subsequent generations,

    leading in turn to an overall deterioration of the human race. The

    degenerate offspring of such defective bloodlines were said to recapitulate

    in their bodies pathological organic characteristics of a number of previous

    generations; and any such individual is not only incapable of becoming part

    of the chain of transmission of progress in human society, he is the greatest

    obstacle to this progress through his contact with the healthy portion of the

    population.

    This dystopian vision apparently had broad appeal, spreading rapidly

    throughout the European psychiatric community and into other intellectualcircles. It was the first manifestation of social Darwinism, generating a

    climate of fear that these natural processes would result in the downfall of

    civilization. Another French psychiatrist, Valentin Magnan, fanned the

    flames by declaring that society was in a hereditary struggle for life, and

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    grimly proposing that society combat it with a rigorous form of social

    hygiene. A popular bestseller in the 1890s, Max Nordaus Degeneration,

    analyzed the allegedly degenerate characteristics of modern art, music, and

    literature. Although degeneration theory fell into disfavor amongpsychiatrists early in the next century, its allure persisted among

    antidemocratic circles in Europe, eventually spawning the genocidal policies

    of Hitlers Nazi regime.

    But the more immediate effect of degeneration theory was that it was

    very bad for business. People with psychiatric complaints began to suppress

    their symptoms, and avoided psychiatrists for fear of being branded with a

    stigmatizing diagnosis. Likewise family members resisted taking family

    members in for care, because of the legitimate fear that their whole family

    might bear the stain of being degenerate carriers of what was perceived to

    be inheritable disease. Having thus succeeded in undermining the economic

    viability of their own profession, psychiatry was forced to figure a way out of

    the corner into which they had painted themselves.

    The answer was the adoption of a nonscientific euphemism, nerves or

    nervous disease, for the low-intensity psychiatric disorders that were the

    bread and butter of office-based practice. Never mind that this appellation

    deceptively implied that the origin of such complaints existed in the

    peripheral nervous system, rather than the brain. In order to avoid the stigma

    of psychiatric illness and ensure their participation in treatment, it was an

    acceptable compromise to tell patients what they wanted to hear rather thanthe perceived truth. Such disorders were typically attributed to overwork,

    stress, or humoral imbalances, despite the widely held (but unspoken)

    belief among psychiatrists that they were genetic or constitutional in nature.

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    The definitive nervous diagnosis emerged in 1869, when a New York

    electrotherapist, George Miller Beard, discovered (i.e. contrived)

    neurastheniaa disease entity attributed to physical exhaustion of the

    nervous system brought on by the stresses of modern living. It embraced avast grab bag of symptoms, including dyspepsia, headaches, insomnia,

    weakness, dizziness, fainting, anesthesia, menstrual irregularities, and wet

    dreams. Beards proposed mechanism was that the central nervous system

    becomes dephosphorylized, or perhaps, loses somewhat of its solid

    constituents. This wispy stab at science was apparently enough for the

    psychiatric community, as the diagnosis became widely accepted in both

    America and Europe.

    Clinics and hospitals embraced the new paradigm by changing their

    namesinstitutions previously designated for the insane were now for

    nervous disease. However, the continued presence of degenerate

    psychiatric patients in such institutions continued to inhibit use of these

    facilities by those who could afford other options. In 1875 Silas Weir Mitchell

    proposed the definitive treatment for neurasthenia, the rest cure. This

    regimen called for the patient to be isolated from stress and excessive

    stimulation, with special diets (such as the popular milk diet) and a melange

    of physical therapies that might include water therapy, electrotherapy, and

    massage. This cure could be delivered at private clinics or sanitariums, but

    the definitive environment for treatment were the spa clinics that sprung up

    on both sides of the Atlantic. Many of the patients were upper class women,providing an enthusiastic (and lucrative) clientele for nerve doctors and the

    facilities to which they referred patients. It was a classic win-win scenario

    after all, who doesnt like rest? And who doesnt like spas?

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    A notable effect of the nervous branding of psychiatric disorders was

    that it opened the door for neurologists to treat psychiatric complaints. The

    office practice of psychiatry was shepherded into being by neurologists, since

    most psychiatrists of the time were affiliated with the asylums. It wasneurologists who observed that the success of these cure models depended

    in large part on a rigorously structured regimen that was imposed under the

    benign authority of an administering physician, which had a powerful effect

    on its largely female clientele. The suspicion grew that the primary

    therapeutic benefit arose from the act of submission itself, suggesting that

    these disorders were more functional (i.e. psychological) than organic. If so,

    this powerful doctor-patient relationship could be moved out of the

    sanitariums and spa clinics into the more cost-effective environment of the

    doctors office. This led to the emergence of psychotherapy and hypnotherapy

    ironically promoted by neurologists rather than psychiatristsand to the

    eventual ascendance of one neurologist who would come to dominate

    psychiatry for half a century.

    The vogue for spa treatment peaked around 1900, waning as the

    number of overtly psychiatric patients at these facilities increased, which

    considerably diminished the euphemistic cache of nervous disease. The era

    stands as a compelling illustration of just how far psychiatry was willing to

    compromise its scientific credibility in response to commercial

    considerations. Remarkably, neurasthenia still appears on the World Health

    Organizations official list of diseases, the ICD-10, since it continues to beused in Asia as a culturally acceptable diagnosis in order to avoid the stigma

    of mental illness.

    Although the historic focus of neurology had previously been organic

    disease, the persistent stigmatization of psychiatrists offered neurologists a

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    steady flow of paying customers seeking help for psychoneurosis.

    Numerous theories were proposed, and different therapeutic approaches were

    explored including hypnosis. In Vienna Sigmund Freud was impressed by

    how many sexual issues were emerging in his psychotherapy practice(treating many young female patients), and he began to develop a body of

    theory that gave a primacy to sexuality never before contemplated. This

    naturally courted controversy and derisionbut also stimulated a lot of

    interest and discussion. He successfully cultivated an intellectual following in

    and around Vienna that grew to become an international movement, while

    laying the foundation for a new treatment model known as psychoanalysis.

    As a social revolutionary I revere Sigmund Freud. His frank discussion

    of sexuality cut through Victorian repression and propriety like a buzzsaw,

    and changed our world forever. Freuds ideas triggered a seismic shift of

    Western culture away from repressive decorum toward candor and sexual

    freedom, ushering in the acknowledgement and celebration of sexuality in art

    and media. He made invaluable contributions as well to the evolution of

    psychological theory and treatment, such as delineating the role of the

    unconscious in human behavior and developing the technique of free

    association. His definitions of the id, ego, and superego, his observation of

    psychological defenses, and much of drive theory in general are still useful

    concepts that facilitate the exploration and discussion of psychological

    problems.

    But as a scientist, Freud was an utter disaster. He was hopelessly inlove with his own opinions, lacking the humility to entertain doubt of his

    interpretations. He was stubbornly fixated on sexuality as causation, which

    made him a better revolutionary but a lousier theoretician. Since his

    hypotheses were ill-suited for examination using the scientific method, he had

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    free rein to build consensus in the psychiatric community through a

    combination of personal charisma and sheer chutzpah. His intellectual

    domination of psychiatry was imposed by the coercive abuse of

    psychoanalytic terminology to attack his opponents, dismissing criticism ofhis theories as psychological resistance or denial. This technique was

    emulated by his legion of followers, who managed to sustain a cultish ideology

    for decades that was virtually impervious to rigorous reexamination.

    To illustrate the absurdity of some of Freuds ideas, I offer for your

    consideration the concept ofpenis envy. According to Freuds psychosexual

    development theorywhich, strictly speaking, shouldbe referred to as a

    hypothesischildren of both sexes first exhibit a libidinal focus on the genital

    area during the phallic stage of development, occurring from age 3 to 6.

    Freud proposed that the penis becomes the organ of primary interest for both

    sexes, triggering a series of events that result in different outcomes for each

    gender due to their differences in anatomy. These events constitute the

    Oedipal complex in boys, characterized by castration anxiety; while in girls

    they are referred to as the Electra complex, the context within which penis

    envy arises and is then resolved.

    Freud proposed that at the beginning of the phallic stage the girl

    develops her first sexual impulses, which are directed toward her mother. She

    then realizes that she does not have the requisite anatomical equipment for

    that sexual relationship, and comes to desire a penis and the power that it

    representshence experiencing penis envy. The solution is to obtain a penis,leading her to develop a sexual desire for her father, an urge that impels the

    elimination and replacement of her mother. The girl concurrently blames the

    mother for her apparent castration, which she presumes is retaliation for

    daring to compete with her mother for her fathers attentions. Eventually the

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    girl begins to identify with and mimic her mother in order to be a better

    replacement, but this in turn leads to fear of further retaliation. All this

    tension is at last relieved utilizing the psychological defense of displacement,

    through which the girl transfers her discomfiting attraction from her father tothe more attainable and acceptable object of men in general.

    I dont know about you, but I lost count of the number of intuitive leaps

    attempted by Freud within this one hypothesis. The scientific method calls

    for observation and testing to confirm a hypothesis, but my bet (and hope) is

    that Freud never directly questioned a sample of 3- to 6-year-old girls to

    explore what feelings they had about their absent penismuch less all the

    other areas of conjecture here. Whats most baffling, however, is that this

    bizarrely tortuous conceit was not the idiosyncratic delusion of some crackpot

    on the fringe, but a core tenet of the analytic canon, advanced by the man who

    was the reigning figure of American psychiatry for most of the 20th Century.

    When psychiatrists conferred with each other on individual cases penis envy

    would be discussed as a matter of course, and rarely if ever questioned as a

    clinical entity. Meanwhile, the coeval cultural phenomenon of penis

    narcissismthe preferential allotment of wealth, power, and personal

    freedom to those fortunate enough to be born with a peniswent entirely

    unnoticed by the (predominantly male) psychoanalytic community. Go

    figure.

    Untethered by the scientific demand for objective verification, and

    inspired by Freuds example, psychoanalysts ran rampant with half-bakedtheories to explain the inner workings of the mind and the pathogenesis of

    psychiatric disease. One of the more reckless of these speculations was Frieda

    Fromm-Reichmanns proposal in 1948 that the degenerative neuropsychiatric

    disease known as schizophrenia was caused by a schizophrenogenic

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    mothera hypothesis that in retrospect appears transparently motivated to

    justify the use of psychotherapy to treat this disorder. According to Fromm-

    Reichmann, such a mother was domineering and overprotective, yet

    emotionally rejected the child, triggering the eventual rise of psychosis as thechild became painfully distrustful and resentful of other people. This

    supposition was accepted and reiterated by the psychiatric community for

    decades, maligning a generation of mothers who probably felt bad enough

    having a schizophrenic child without being told they were to blame for their

    misfortune. Eventually this hypothesis was debunked by actual scientific

    research, apparently because somebody felt that such a charge merited

    investigation rather than mere assertion.

    Meanwhile, Melanie Klein proclaimed that the origins of psychosis were

    in the first six months of life. Klein proposed that in order to develop

    properly the infant has to split its world into good and bad objects, because

    doing so prevents the perception by the infant that good is being destroyed by

    the bad. Integration of good and bad is anticipated in normal development

    once the child matures to a point that it is able to safely tolerate ambivalence

    and conflict. However if the needs of the baby are not met promptly on a

    regular basis because the mother is not there to fulfill them, the absence of the

    good object is experienced as the bad object. In fantasy the baby attacks the

    bad object, and in turn fears that the bad object will retaliate. As a result the

    baby grows up feeling persecuted, and develops chronic paranoia in dread of

    the bad objects inevitable revenge.Cleverly, Klein had managed to concoct a hypothesis that noone can

    ever prove ordisprove.

    Countless volumes of academic literature were filled with such

    propositions during the psychoanalytic era. These suppositions carried on

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    psychiatrys established tradition of making shit up, now refined to

    stratospheric new heights of convoluted audacity. They arise from the same

    brand of science that brought us the theory of intelligent designthe

    conviction that something must be true because it sounds good, feels right,and supports my existing world view. Except intelligent design is more

    elegant and firmly grounded in reality.

    So how could this sort of poppycock have risen to prominence in a

    century notable for huge leaps in scientific progress? Well, the biggest

    contributing factor was Freuds rock star status in American popular culture.

    Freud had been on the money in confronting the stultifying sexual repression

    of the Victorian era, and clarifying the role of the unconscious in human

    behavior. These concepts had a profound cultural impact over and above his

    influence as a clinician, spilling over into art and literature. He single-

    handedly inspired the surrealist movement, and overtly Freudian references

    can be found in Hitchcock movies and other popular media of the era. To this

    day Sigmund Freud is probably the only psychiatrist that most lay people can

    name.

    His ideas were an object of fascination among the chattering classes

    who not only elevated his stature, but made up much of the psychoanalysts

    natural consumer base. Never before had psychiatry experienced such social

    cache. For better or worse, psychiatry was publicly branded by Freuds

    preeminenceso when paying patients came into a psychiatrists office

    expecting Freudian therapy, they were likely to be obliged. And ifpsychiatrists could get their rambling speculations published and discussed

    without having to do the grunt work of actual research, it would be hard for

    anyone with a healthy ego to resist.

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    Freuds impact was not only cultural and clinical, but commercial as

    well. Before Freud the practice of psychiatry was primarily based in the

    asylum, where the severely ill could be safely housed and treated. Emerging

    from neurology to address low-intensity psychiatric complaints in an office-based practice, Freud revolutionized our profession. As historian Edward

    Shorter states, Psychoanalysis was the caisson on which American psychiatry

    rode triumphantly into private practicerescuing psychiatrists from the

    asylums, and creating the practice model that has endured even into this

    medication-oriented era.

    However, its worth noting that two centuries of psychiatric research

    prior to the advent of psychoanalysis had produced little of lasting clinical

    value. As I noted earlier, the obstacles to understanding the brain and its

    functions are formidable, and prior to the 20th Century the available

    technological means were simply not up to the task. Unfortunately the early

    pioneers in the field tended to have more gumption than wisdom, consistently

    overestimating their level of understanding and generating a succession of red

    herrings disguised as theories, that merely waylaid earnest scientific study

    rather than advancing it. Over this entire period there was only one major

    psychiatric figure whose discoveries remain clinically relevant todaya

    German psychiatrist who was humble enough to know the limits of his means,

    to appropriately narrow his focus, and to strictly adhere to the scientific

    method.

    That man was Emil Kraepelin, head of the university psychiatric clinicin Heidelberg, who over the course of the 1890s carried out methodical

    research of patients who were admitted for severe psychiatric illness.

    Kraepelin was a notably independent and plainspoken figure for his time. He

    came into the profession with a psychological orientation, and was offended

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    by the rude indifference his teachers often demonstrated toward patients. He

    rejected the biological fixation of most of his peers, since their extensive

    anatomical study had already proven fruitless in identifying the causes of

    psychiatric illness. He decided early on that the technological meansavailable made it impossible to speculate regarding causation in these cases,

    accepting this limitation rather than leaping to uninformed conclusions.

    Instead he concentrated his research on the bedside observation of patients

    over an extensive period of treatment, with a focus on identifying predictors

    of disease course. He did so in hope of identifying discrete diagnostic entities,

    so they could be further studiedbut also saw it as a clinical priority, since

    loved ones so often wanted to know whether patients would improve and

    when. As Kraepelin stated:

    The doctors first task at the bedside is being able to form a

    judgment about the probable further course of the case. People

    always ask him this. The value of a diagnosis for the practical

    activity of the psychiatrist consists of letting him give a reliable

    look at the future.

    With this goal in mind, he gathered extensive data regarding these

    patients, analyzing his findings in an attempt to cut nature at the joints and

    identify specific disease states. He noted that patients presenting with

    psychosis shared many common symptoms, but had wildly differing coursesof their disease. After prolonged study, he observed that patients with a high

    degree ofaffective (i.e. emotional) content had episodes that swung in a

    cyclical patter, with full recovery of function between these episodes. He

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    called this condition manic-depressive illness, a disorder now technically

    designated as Type I Bipolar Disorder.

    Patients lacking this affective content, on the other hand, trended

    toward a degenerative course of illness that was unremitting, exhibiting whathe described as a peculiar destruction of the internal connections of the

    psychic personality, with the most marked damage of the emotional life and

    volition. He coined the term dementia praecoxfor this conditionwhich

    was later renamed schizophrenia, after it became clear that the degree of

    cognitive impairment was insufficient to warrant the term dementia.

    Although he came to believe that schizophrenia was neurodevelopmental in

    origin, he maintained a healthy respect for the non-biological aspects of the

    psyche, touting the therapeutic benefits of meaningful activity (especially

    farming and gardening) in treatment of the mentally ill.

    But Kraepelin was a singular exception in a psychiatric legacy that was

    littered with debunked theories, dead ends, and downright quackery. By the

    dawn of the 20th Century, the entirety of psychiatric research had culminated

    in the exportation of medical diseases (like neurosyphilis and multiple

    sclerosis) to other specialties, and the identification of two actual psychiatric

    diseases that had no known causation or treatmentthe only durable

    psychiatric knowledge to date. In a demoralized state after nearly destroying

    itself with the degeneration debacle, its little wonder that psychiatry latched

    on to Freuds confident authority and public stature.

    As it turned out, psychoanalysis was much more effective for treatingthe worried well than the truely ill. Attempts to apply psychoanalysis to the

    asylum population failed miserably, and outpatients who were unresponsive

    to analysis were often labelled resistant or even bad patients.

    Furthermore it was cost-ineffective, especially in the macroeconomic sense,

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    since the type of patients who were most likely to participate and respond to

    psychoanalysis were those most likely to be able to maintain employment as

    well. In the 1950s psychiatric medications began to improve by leaps and

    bounds, emerging eventually as a more cost-effective treatment optionapplicable to a larger proportion of the patient population, including those

    who were the sickest.

    Even if it flunked science (and economics), psychoanalysis certainly

    deserves an A for effort. In analysis, diagnosis was a demanding process that

    took place over weeks, months, even years, as ever deeper thoughts and

    feelings were revealed in the course of therapy. As convoluted and speculative

    as a diagnostic formulation might be, it was an earnest attempt to understand

    the patients personality and problems, and to communicate a patients story

    without gross oversimplificationand hence inherently respectful of just how

    complicated any human being really is. Old school analysts have been some

    of the most passionate critics of biological psychiatrys crass reductionism

    which is not surprising, given that there always was an element of romance to

    psychoanalysis that impelled many of its practitioners.

    But theres simply no place for romance in science, since that inevitably

    entails attachment to an idea you may have to dispose of later. Most of the

    figures cited in this chapter were true believers, passionately attached to their

    own ideas or those of their mentors. Any of them who lived long enough saw

    their cherished doctrines crushed by whatever passed for progress in that

    era. The notable exception was Kraepelin, a scientist rather than a believer,whose discoveries have accordingly endured to this day.

    Contemporary psychiatry has good reason to be ashamed of its history.

    But if the apparent neglect of its checkered past is by design, I suspect there

    are deeper motives beyond mere embarrassment. Over the years we have

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    habitually underestimated our scientific task, and overplayed our clinical

    hand. Having finally achieved a tenuous foothold on medical legitimacy, its

    natural to assume that we might be threatened by a history that challenges

    that stature. The new technologies are indeed powerful, and the resultanttreatments are undoubtedly more effective than ever before. But it would be

    foolhardy to overlook psychiatrys established proclivity for bending science

    to its willand to discount the very real possibility that our current dogma is

    just the latest manifestation of that regretful tendency.

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