lymphatic system
DESCRIPTION
LYMPHATIC SYSTEM. CHAPTER 12. LYMPHATIC SYSTEM. CONSISTS OF 2 PARTS LYMPHATIC VESSELS- transport fluids that have escaped the cardiovascular system called LYMPH 2.LYMPHATIC ORGANS- (lymph nodes)- filter the fluid and kill off invaders with lymphocytes. Lymphatic Vessels. - PowerPoint PPT PresentationTRANSCRIPT
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CHAPTER 12
LYMPHATIC SYSTEM
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CONSISTS OF 2 PARTS
1. LYMPHATIC VESSELS- transport fluids that have escaped the cardiovascular system called LYMPH
2. LYMPHATIC ORGANS- (lymph nodes)- filter the fluid and kill off invaders with lymphocytes
LYMPHATIC SYSTEM
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Very similar to veins with lymph capillaries becoming successively larger and eventually called LYMPHATIC COLLECTING DUCTS. Have valves very similar to veins that help to move lymph
RIGHT LYMPHATIC DUCT – collects lymph from the right arm and right thorax and right head- drains into the subclavian vein
THORACIC DUCT- collects lymph from the rest of body – drains into the sub clavian vein
Lymphatic Vessels
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-KIDNEY SHAPED-ABOUT 1 INCH LONG-about 1000 found in the body-contains large amounts of lymphocytes –B
cells and T cells-FOUND IN CLUSTERS IN 3 MAJOR REGIONS
1. AXILLARY– (armpit)2. CERVICAL- (side of neck)3. INGUINAL- (groin)
LYMPH NODES
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SPLEENTHYMUSTONSILSPEYER’S PATCHES
LYMPH ORGANS
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Located on the left side and curls around the stomach
Filters the blood of bacteria, viruses and other debris
Breaks down worn out RED BLOOD CELLS so hemoglobin can be reused.
Storage site of blood.Produce Lymphocytes
SPLEEN
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Produces hormones- thymosin that programs lymphocytes
Located low in the throat
More active in youth
THYMUS
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Lymphatic tissue located in the pharynx-
Trap bacteria entering the pharynx
May become sore and swollen called --- TONSILITIS
TONSILS
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“tonsils” of the small intestine
Capture bacteria that are found in the digestive system.
MUCOSA-ASSOCIATED LYMPHATIC TISSUE(MALT) consists of tonsils and Peyer’s patches which protect the respiratory and digestive tracts from never-ending invasion
PEYER’S PATCHES
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SKIN-SWEAT contains a low pH level preventing bacterial growthSEBUM- contains chemicals toxic to bacteriaVAGINAL SECRETIONS- highly acidic
NON SPECIFIC DEFENSE SYSTEMS
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STOMACH- hydrochloric acid is highly acidic
SALIVA- contains lysozomes- enzyme that kills bacteria
MUCUS- traps organisms from entering the digestive and respiratory systems
NON SPECIFIC DEFENSE SYSTEM
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Immunity
- New particles take longer to identify, and a person remains ill until a new antibody can be crafted
- Old particles are quickly recognized, and a person may never become ill from that invader again. This person is now immune.
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STEM CELL– undifferentiated cells made in the red bone marrow (can become Lymphocytes or Granulocytes)
LYMPHOCYTES- NATURAL KILLER CELLS- protect us from tumored cells and virus
infected cells
B CELLS- (bone cells) lymphocytes that mature in the bone marrow-produce antibodies, help present antigens., and form Memory B cells
T CELLS- (Thymus cells) lymphocytes that mature in the thymus- do not produce antibodies– but do release chemicals to spend up phagocytosis by MACROPHAGES- become T HELPER cells that help in the maturity of B cells and Cytotoxic T cells that aid tumored cells and in organ rejection
CELLS OF THE IMMUNE SYSTEM
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GRANULOCYTESNEUTROPHILS- 1st responder to infection site- “phagocytize”
EOSINOPHILS- phagocytize parasites and help with allergic reactions and asthma
BASOPHILS– contains vasodilator HISTAMINE and anticoagulant HEPARIN with aide in the INFLAMMATION RESPONSE
MONOCYTES- stored in the spleen can become MACROPHAGES or DENDRITIC CELLS
CELLS OF THE IMMUNE SYSTEM
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DENDROCYTE
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1. INFLAMMATORY RESPONSE- general
2. ANTIGEN SPECIFIC RESPONSE-
2 types of responses
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INFLAMMATION RESPONSE---
(Histamines)
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Any substance capable of setting off an immune response.
Almost all things are ANTIGENIC (including our own cells) but our body had learn to identify our cells and these SELF-ANTIGENS (Human leukocyte antigen- HLA) do not trigger an immune response in us.
ANTIGEN
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Antibody Production1. MACROPHAGES-gobble up
invading particles and break them up
2. They show the ANTIGEN pieces to T-cells, who identify the pieces
3. T CELLS help to find specific B-cells to help
4. B-cells produce antibodies that are equipped to find that specific antigen on a new cell.
5. Memory B cells are also made- for future attacks
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ANTIBODIESalso known as an
immunoglobulin, is a large Y-shaped protein used by the immune system to identify and neutralize foreign objects like bacteria and viruses
May be free flowing or attached to B cells
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Active Immunity- You produce the antibodies
- Your body has been exposed to the antigen in the past either through:- Exposure to the actual disease causing antigen –
You fought it, you won, you remember it- Planned exposure to a form of the antigen that has
been killed or weakened – You detected it, eliminated it, and remember it
What is this second type of exposure called?
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Vaccine----Passive ImmunityAntigens are deliberately introduced
into the immune system to produce immunity
Because the bacteria has been killed or weakened, minimal symptoms occur
Have eradicated or severely limited several diseases from the face of the Earth, such as polio and smallpox
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Immune Disorders~Allergies~
- Immune system mistakenly recognizes harmless foreign particles as serious threats
- Launches immune response, which causes sneezing, runny nose, and watery eyes
- Anti-histamines block effect of histamines and bring relief to allergy sufferers
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Aquired Immune Deficiency Syndrome
Caused by the Human Immunodeficiency Virus
Discovered in 1983Specifically targets and
kills T-cellsBecause normal body
cells are unaffected, immune response is not launched
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MULTIPLE SCLEROSIS- immune system attacks the myelin sheath of the nervous system
MYASTHENIA GRAVIS
GRAVES DISEASE
AUTOIMMUNE DISEASES