Lyme DiseaseLyme Disease

A New Name for an Old

Condition?

A New Name for an Old

Condition?

Cecile JadinSouth AfricaCecile JadinSouth Africa

August 2008, Sonoma County California

Continued Discontinuity In Microbiology

Continued Discontinuity In Microbiology

Examples: H.Pylori,Leishmaniosis, Trypanosomiasis, Toxoplasmosis, Rickettsia…

Slows down progress in research Masks the pandemia of today's germs - already highlighted by Homer in the sixth section of the Iliad: “migration of gulls who every winter carry the carnage and war from one end of the earth to the other”

Medicine is built mainly on new findings If this were the case for Mathematics and Physics, how chaotic would it be?

Examples: H.Pylori,Leishmaniosis, Trypanosomiasis, Toxoplasmosis, Rickettsia…

Slows down progress in research Masks the pandemia of today's germs - already highlighted by Homer in the sixth section of the Iliad: “migration of gulls who every winter carry the carnage and war from one end of the earth to the other”

Medicine is built mainly on new findings If this were the case for Mathematics and Physics, how chaotic would it be?

Borreliosis’ Case

Borreliosis’ Case Drury discovers Malgache fever in 1702 - Central

Africa Early 1900’s Spirochete hispanicum in Spain A few years later, Nicolle tracks Malgache fever -

Northern Africa Scheltz, while working in Congo in 1933, reports

the same recurrent fever associated with spirochete

In 1944, Palakov publishes that the relapsing fever disabling patients in Cape Town is due to the same bug

Heisch claims the recognition of Borreliosis as causing the never-ending fever in 1950 - Kenya

Borrelia burgdoferi, isolated in 1982 by Willy Burgdorfer after a mysterious outbreak of arthritis in Connecticut in 1975, is Americanised as Lyme disease

Drury discovers Malgache fever in 1702 - Central Africa

Early 1900’s Spirochete hispanicum in Spain A few years later, Nicolle tracks Malgache fever -

Northern Africa Scheltz, while working in Congo in 1933, reports

the same recurrent fever associated with spirochete

In 1944, Palakov publishes that the relapsing fever disabling patients in Cape Town is due to the same bug

Heisch claims the recognition of Borreliosis as causing the never-ending fever in 1950 - Kenya

Borrelia burgdoferi, isolated in 1982 by Willy Burgdorfer after a mysterious outbreak of arthritis in Connecticut in 1975, is Americanised as Lyme disease

The Vector is Known

The Vector is Known

Life span of 4 Years Walking distance of 50 meters/life time Can lay 1000 eggs Can be genetically infected - trans-ovarian transmission of Rickettsia has been observed

Is more virulent than ever: Insecticides: tick & eating birds Global Warming Traffic intensity

More than one organism is needed to collapse the immune system

Life span of 4 Years Walking distance of 50 meters/life time Can lay 1000 eggs Can be genetically infected - trans-ovarian transmission of Rickettsia has been observed

Is more virulent than ever: Insecticides: tick & eating birds Global Warming Traffic intensity

More than one organism is needed to collapse the immune system

Ixodes Ricinus & OthersIxodes Ricinus & Others

Lyme is a tick-born Lyme is a tick-born diseasedisease

Lyme is a tick-born Lyme is a tick-born diseasedisease

A tick contains an A tick contains an average of 80 germsaverage of 80 germs

Check as many tick-born Check as many tick-born diseases as your lab diseases as your lab offers in presence of offers in presence of insect bites or close insect bites or close contactcontact

Our Diagnostic ToolsOur Diagnostic Tools

Medical history - Insect Bite? Contact?

Symptomatology - Headaches? Chills? Fatigue? Muscular & Joints Pains? Carditis?…

Medical examination - Rash?… Biological investigation

Medical history - Insect Bite? Contact?

Symptomatology - Headaches? Chills? Fatigue? Muscular & Joints Pains? Carditis?…

Medical examination - Rash?… Biological investigation

Biological InvestigationBiological

InvestigationInfections Rickettsia Prowazeki R. Mooseri R. Conori Q Fever Mycoplasma Pneumoniae Chlamydia Pneumoniae Chlamydia Trachomatis Chlamydia Psittaci Brucellosis Toxoplasmosis H. Pylori Bartonella Lyme Disease: Direct examination preferred Bilharzia

Infections Rickettsia Prowazeki R. Mooseri R. Conori Q Fever Mycoplasma Pneumoniae Chlamydia Pneumoniae Chlamydia Trachomatis Chlamydia Psittaci Brucellosis Toxoplasmosis H. Pylori Bartonella Lyme Disease: Direct examination preferred Bilharzia

DysfunctionDysfunction FBC ESR LFT TFT & Thyroid antibodies IgE Iron Study Kidney Study Glucose CRP RF ANF Cardiolipin Cholesterol

FBC ESR LFT TFT & Thyroid antibodies IgE Iron Study Kidney Study Glucose CRP RF ANF Cardiolipin Cholesterol

Biological WindowBiological Window

0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

Rickettsial InfectionLympho Study

Chlamydiae non specBartonella

LFTMycoplasma

IronCRP, RF, ANF

BorreliosisToxoplasmosis

Thyroid ABFBC (abs

ESRKFTTFT

500 Patients Randomly Sampled500 Patients Randomly Sampled

1 Germ Different Diseases1 Disease Different Causes1 Germ Different Diseases1 Disease Different Causes According to its position in the human body, spread throughout the Reticulo- Endothelial tissue

According to its specific toxicity

Facing the physiological conditions of the host

Symbiosis of germs

According to its position in the human body, spread throughout the Reticulo- Endothelial tissue

According to its specific toxicity

Facing the physiological conditions of the host

Symbiosis of germs

Neurological Disease Psychiatric Disease Rheumatologic Disease Cardio-Vascular Disease Dermatologic Disease Etcetera

Neurological Disease Psychiatric Disease Rheumatologic Disease Cardio-Vascular Disease Dermatologic Disease Etcetera

One disease at a timeOne disease at a timeOne disease after anotherOne disease after anotherAll diseases togetherAll diseases together

One disease at a timeOne disease at a timeOne disease after anotherOne disease after anotherAll diseases togetherAll diseases together

Experience with Treatment

Experience with Treatment

Established by French school 30 years ago, used in our clinic since 1992

Antibiotics Preferably orally - except for Ceftriaxone Pulse Therapy as opposed to continuous High Dosage Associated - Bacteriostatics + Bactericidals Alternated With Adjuvants: vit B com - probiotics - gastric proton inhibitor

Vaccination - Mutation - Relapse

Established by French school 30 years ago, used in our clinic since 1992

Antibiotics Preferably orally - except for Ceftriaxone Pulse Therapy as opposed to continuous High Dosage Associated - Bacteriostatics + Bactericidals Alternated With Adjuvants: vit B com - probiotics - gastric proton inhibitor

Vaccination - Mutation - Relapse