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Luis Oppenheimer, MD, PhD, FRCS(C), FACS

EDUCATION Undergraduate 1969 University of Barcelona Medical School Internship 1971-1972 Health Sciences Centre, Winnipeg, Manitoba Post-Graduate 1972-1975 Residency in Surgery, University of Manitoba

1975-77 Research Fellowship, University of Manitoba Respiratory Investigation Unit 1977 Chief Resident, Dept. of Surgery University of Manitoba

Certification 1977 F.R.C.S.(C) Fellowship 1978 Trauma Fellow, Univ. of California

San Francisco General Hospital Doctoral (PhD) 1994 Department of Physiology, University of

Barcelona, Spain.

HONORS AND AWARDS 1981 - 1995 Myles Robinson Memorial Heart Trust

Scholarships (15 years) 1991 Manitoba Medical Association Scholastic

Award 1991 City of Winnipeg's Outstanding Achievement

Medal (Award of Excellence) 1998-99 President Manitoba Chapter, American College

of Surgeons 2007 Manitoba Medical Association Health

Administration Award 2011 College of Family Physicians of Canada –

Honorary Membership CLINICAL PRACTICE

Health Sciences Centre, University of Manitoba Trauma Surgery (General Surgery) until 2008 and Critical Care in the Surgical Intensive Care Unit at the Health Sciences Centre, Winnipeg until present.

ACADEMIC & ADMINISTRATIVE APPOINTMENTS July 2012 – Present Provincial Director of Clinical Improvement and Access,

Manitoba Health Sept 2006 – June 2012 Provincial Director for Patient Access and Clinical System

Improvement, Winnipeg Regional Health Authority Feb 2007 – Present Medical Director, MBTelehealth

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1989 – Present Professor, Department of Surgery, University of Manitoba Mar 2010 – Feb 2015 Professor, Department of Family Medicine, University of

Manitoba Sept 2006 – June 2009 Assistant Dean, Innovation in System Design and Quality,

Faculty of Medicine, University of Manitoba 1995 - 2006 Professor and Head, Department of Surgery 2000 – 2006 Medical Director, Surgery Program, Winnipeg Regional

Health Authority (WRHA) 1998 - 2000 Medical Director, Surgery Program, Winnipeg Hospital

Authority 1982 - 2004 Associate Professor, Department of Internal Medicine,

University of Manitoba 1988 - 1995 Associate Professor, Department of Pharmacology,

University of Manitoba 1991 - 1995 Adjunct Professor, Department of Physiology, University of

Manitoba HOSPITAL APPOINTMENTS Since 1978 Attending Staff, Department of Surgery, Health Sciences

Centre and St. Boniface General Hospital 1987 - 1995 Director, Surgical Intensive Care Unit, Health Sciences

Centre. 1992 - 2000 Director of Research, Health Sciences Centre and Director

of Research, Health Sciences Centre Foundation 1995 – 2006 Surgeon in Chief, Health Sciences Centre and St. Boniface

General Hospital SOCIETY MEMBERSHIPS Present Manitoba Medical Association Canadian Medical Association Royal College of Physicians and Surgeons (C) Canadian College of Family Physicians (Honorary). Canadian Medical Protective Association Canadian Association of Clinical Surgeons Canadian Critical Care Society Fellow of the American College of Surgeons (FACS) Society of Critical Care medicine Past American Physiologic Society Microcirculatory Society Canadian Society for Clinical Investigation Canadian Association of Clinical Surgeons Trauma Association of Canada

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American Association for the Surgery of Trauma INITIATIVES 1. Developed the Masters in Surgery Programme - 1988. 2. Strategic Planning Process for the Department of Research at the Health Sciences

Centre (1993-94). 3. Proposal and implementation for a Trauma and Acute Care Service for the Health

Sciences Centre. This service has been in existence now since 1995. It is an example of Integrated Referral Service.

4. Development of Health Trials Inc. (Department of Research HSC), 1995. 5. Development of Manitoba Tele - Medicine (Department of Research), 1995. Now

under WRHA. 6. Projects in Health Technology Assessment (Department of Research), 1995. 7. Introduction of the Cardiac Waiting List as part of the Cardiac Network of Ontario,

1998. 8. Functional Plan for the Buhler Research Centre (1998 – 2000). 9. Introduction of the Orthopedic Surgery Waiting List, 1999. 10. First phase of the Service Integration Project, aiming at reorganizing the

continuum of arthroplasty care, bridging Community, Hospital and Rehabilitation Services (1998 – 1999).

11. Development of a Business Plan for the establishment of a Gamma Knife Facility at the HSC in Winnipeg. Participated in the successful implementation of the plan. It has been running successfully since November 2003.

12. Introduced Clinical Assistants (Physician Assistants), into the Surgery Program (2002 – present). These new health professionals are now part of: Cardiac, Vascular, Orthopedic, Plastic, Trauma and Neurosurgery for a total of 16 positions. This has been very successful, and the number is increasing.

13. Instrumental in establishing Manitoba as a clinical site for the training of Physician Assistants for the Canadian Armed Forces (2003).

14. Established a bilateral collaboration with the European Institute of Tele - Surgery, for the purposes of training Winnipeg surgeons in minimally invasive techniques. Since April 2003.

15. Initiated a demonstration project to perform limited laparoscopic surgery at the Pan Am Surgery Center (Stand alone ambulatory center), 2005.

16. Spearheaded the establishment of an Academic Arthroplasty Unit at Concordia Hospital (small community hospital) in 2002. In three years, the annual volume has increased from about 100 to about 1600 joint replacements/year. Plans project increases to 2400 in 2006).

17. Since January 2003, spearheaded the entire reorganization of Surgical Services in the Winnipeg Health Region. This involved repeated presentations to the Minister of Health, cabinet, WRHA Senior Management, Hospital CEOs, stakeholders (a total of 108 presentations) and close collaboration with the various surgical specialties in the city.

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18. Development of a citywide Orthopedic Action Group for the purposes of rationalizing Orthopedic Trauma and moving towards a Centrally Managed Waiting List (2004 – present).

19. Development and introduction of a Pre – Habilitation Programme, aimed at the systematic review and optimization of patients in the Joint Replacement Waiting List. (2005 – present). This Programme represents a multidisciplinary approach to practice, including physicians, nurses, physiotherapists, occupational therapists, dietitians, social workers, pharmacists and psychologists.

20. Introduction of Telephone and Web based multidisciplinary questionnaires for the purpose of assessing medical, functional and other status of patients on the Joint Replacement Waiting List. This information allows planning of resource requirements for arthroplasty surgery and is allowing us to change from a traditional batch and queue to a pull through system (2005 – present).

21. Written proposal, and obtained approval from the University of Manitoba to develop the Centre for Healthcare Innovation at the Health Sciences Centre Campus. The Centre brings together members of the health professions and faculty from engineering, business and science. Approval was obtained in June 2008. The Centre has been in operation since.

22. In conjunction with Manitoba Health’s Wait Times Task Force (WTTF), developed Web based Catalogue of Specialized Services, in an effort to help primary care providers refer to the right specialist, thus helping patient access. (2007 – present)

23. Also in conjunction with the WTTF and funded by Health Canada (5.6M), undertaken a collaborative project (Bridging General to Specialist Care), where criteria for referral were developed jointly by 154 family physicians and 49 specialist. This electronic referral system is in early deployment and testing. (2007 – present)

24. Early phases of an Advanced Booking System, where family physicians and patients, jointly may book required services with the specialist of their choice at a convenient and clinically acceptable time. (2007 to present)

25. Development of the e-Referral and Consultation System (formerly Bridging General to Specialist Care (BGSC), which is interoperable with EMRs. Funding provided by Canada Health Infoway.

VISITING PROFESSOR & GUEST LECTURER

World Congress of Physiological Sciences, Sydney, Australia, 1983

Alberta Heritage Foundation, 1983

Section of Respiratory Medicine U of A, 1983

Royal College Guest Lecturer Toronto, 1983

Dept. Physiology University of Barcelona, Spain, 1984

Royal Academy of Medical Sciences, Barcelona, Spain,

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1985 (Critical Care Section)

Royal College Guest Lecturer Montreal, 1985

Cardiology National Institute, Mexico City, November 1986 (Visiting Professor)

Department of Physiology (Visiting Professor), University of Southern Alabama, October 1987

Banff Critical Care Symposium, June 1988

Royal Academy of Medical Sciences (Critical Care Section), Barcelona, Spain, 1989 (Guest Lecturer)

Ninth International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium, March 1989

American Thoracic Society (ATS), Boston, MASS, Lung Fluid Exchange lecture, May 1990

1st World Congress on Biomechanics, La Jolla, California, Invited Lecturer, September 1990

Royal College Guest Lecturer, Toronto, 1990

1st Iberio American Congress of Pneumology, Barcelona, Spain, October 1990

Cardiopulmonary Pathophysiology Congress, Mexico City, Mexico, November 1990

Symposium on the Rationale for Use of Natural and Synthetic Colloids in Anaesthesia and Intensive Care, Paris, France, June 1991

Federation of American Societies of Experimental Biology (FASEB), April, Anaheim, California, 1992

American Thoracic Society, Miami, May 1992

Edge of Excellence '91 Conference, "Crises, Controversies and Challenge", November 1992

ARDS Concensus Conference, Miami, 1992

XXIII European Congress on Critical Care Medicine, Barcelona, Spain, October 1992

ARDS American-European Concensus Conference, Barcelona, Spain, 1992

J.D. Culligan Memorial Symposium, "Edge of Excellence Conference: Crises, Controversies & Challenge, Winnipeg, November 1992

Pathophysiology & Techniques of Cardiopulmonary Bypass XIII, San Diego, California, February 1993

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Federation of American Societies of Experimental Biology (FASEB), March, New Orleans, 1993

National Heart Institute, Division of Respirology Medicine, Guest Lecturer, Mexico City, Mexico, April 1993

American Thoracic Society, San Francisco, May 1993

Guest Lecturer - University of Toronto, Division of Critical Care Medicine, June 1993

Guest Lecturer - Mexico City, International Scientific Meeting of the Society of Cardiology, April 1994

Guest Lecturer, International Scientific Nephrology Congress, Mexico City, Mexico, April 1994

Guest Lecturer - Intensive Care Medicine, Innsbruck, Austria, June 1994

Guest Lecturer - Sabadell Hospital, Session of Medical Sciences supported by the Ministry of Health. Presentation: Funding Strategies for Health Research in Canada, Barcelona, Spain, June 1994

Guest Lecturer - National Health Service, Mexico City Mexico. Talk on Funding Strategies for Research in Canada, July 1994

Guest Lecturer - Barcelona, Spain, European Society on Artificial Organs, October, 1994

JD Culligan Symposium, “Alternatives to Blood & Blood Products”, Winnipeg, MB

Second Symposium on Applied Physiology of the Peripheral Circulation, Barcelona, Spain, September 1995

Conference: Institute for Healthcare Improvement, 18th National Forum on Quality Improvement – Orlando, Florida, December 2006

Conference: Institute for Healthcare Improvement, International Forum on Quality and Safety in Health Care – Barcelona Spain, April 2007

Conference: Institute for Healthcare Improvement, International Forum on Quality and Safety in Health Care, Paris France, April 2008

Moderator: Institute for Healthcare Improvement – Health Professions Education Collaborative Conference, Winnipeg, April 2009

Lecturer/Key Note Speaker: Mexican Congress of Respiratory Medicine, Mexico, April 5- 9, 2010

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a. First Congress of Respiratory Nurses re Role of Nurses in Hospital Quality Management/

b. Mexican Council of Medical Education re Quality in Medical Education/

c. Keynote to the Members of the Congress re Pathophysiology of Pulmonary Edema - History, Evidence and Present Challenges

Panel Participant – Health Symposium – On the road to Sustainability – Business Council of Manitoba – December 3, 2010

Panel Participant – Health Symposium – Business Council of Manitoba – March 30, 2012

Co-Presenter – 54th Annual Conference of the Canadian Operational Research Society (CORS) and the 10th international Conference on Multiple Objective Programming and Goal Programming (MOPGP) – Comparative Study of Two Similar, Independently Developed e-Referral Systems, and

Decision Support System to Facilitate the Process of Referral within an e-Referral System – Niagara Falls, Ontario, June 2012

Conference: Institute for Healthcare Improvement, International Forum on Quality and Safety in Health Care, London England, April 2013

RECENT PRESENTATIONS

Nov. 2006 Access to Those Who have Waited the Longest, Reducing Healthcare Wait Times Conference, The Canadian Institute

Feb 2007 Timely Access to Health Care, Health Canada April 2007 Wait List Strategies, WRHA Leadership Lecture Series May 2007 Patient Navigation and Patient Access to the Harkness Tour

of Canadian Health Services Research Foundation May 2007 Wait List Initiative to the Community Health Advisory Council

All Councils Meeting, WRHA July 2007 Eliminate the Wait Public Forum presented by Manitoba

Association of Health Care Professionals November 2007 The Right Care at the Right Time, Can Health Care be

Managed? Manitoba/Canada Health Policy Dialogue #4

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March 2008 Manitoba Leader Forum on Secondary Use of Health Data April 2008 Taming the Queue V Conference, Health Canada April 2009 Interdisciplinary Trauma Rounds, Department of Surgery,

Some Innovative Strategies to Improve Access to Surgical Services

May 2009 51st Annual Scientific Assembly, The Manitoba College of Family Physicians – Keynote: The Future of Medicine

June 2009 COACH eHealth Leadership in Action Conference: Improving Family Physician and Specialist Communication & Coordination; Bridging General and Specialist Care (BGSC); & the Catalogue of Specialized Services (CSS)

October 2009 Bridging General and Specialist Care, Manitoba eHealth Conference

November 2009 Making it Happen: Understanding the Problem First and Analyzing Solutions, Health Innovations Conference

December 2009 Wait Time Management, BGSC, Patient Access, Western Regional Training Centre

January 2010 Bridging General and Specialist Care, Department of Family Medicine Residents, University of Manitoba

March 2010 Wait List to Commitment Lists – WRHA Ethics Council April 2010

April 2010 Health Reform: When Solutions Don’t Fit the Problems – Today’s Healthcare – 2nd Year Medical Students, Faculty of Medicine, University of Manitoba

June 2010 Manitoba Patient Access Tools, Bridging General to Specialist Care and Catalog of Specialized Services – National Health Leadership Conference – Canadian College of Health Service Executives, Winnipeg

March 2011 Manitoba Adolescent Treatment Centre – Management Committee regarding Integrated Community System Collaborative

March 2011 Physician Integrated Network regarding Access May 2011 Health Sciences Centre Surgery Managers regarding Virtual

Wards June 2011 Chinese Visiting Nursing Professors re Virtual Wards Dept of Internal Medicine re Virtual Wards Community Health Services re Integrated Care and Risk

Prediction Manitoba eHealth re Integrated Care

January 2012 Western Regional Training Centre May 2012 Health Sciences Centre Executive re Predicting Patient Use

of the Emergency May 2012 Annual Surgical Program Meeting in Carman, Manitoba

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June 2012 Manitoba eHealth Clinical Advisory Committee re Patient Risk Predictions

November 2012 Mental Health/Primary Care re eReferral / Consultation/MB Telehealth

November 2012 Provincial Medical Leadership Council re Generalist and Specialist Collaboration

October 2013 Provincial Medical Leadership Council re Generalist and Specialist Collaboration

REVIEWER (Journals & Granting Agencies until July 1995) Medical Research Council of Canada Heart & Stroke Foundation of Canada British Columbia Lung Association Alberta Lung Association Journal of Clinical Investigation Journal of Applied Physiology American Journal of Physiology Journal of Cardiology Journal of Biomedical Engineering American Physiologic Society

COMMITTEES – Current

University – Hospitals 1. Section of General Surgery Committee 2. Department of Surgery Council 3. Department of Surgery GFT Committee 4. Section of Critical Care Meeting 5. Critical Care Postgraduate Medical Education Committee

Manitoba Health

1. Ex-officio Member, Manitoba Patient Access Network (May 2006 to present) 2. Member, The Manitoba Technical Advisory Committee in a Stroke Program and

Services (March 2008 to present 3. Member, Physician Integration Network (PIN) Advisory Group – Primary Care

Initiative (May 2008 to present 4. Member, Health System Innovation (2010 to present) 5. Member, Manitoba Health Stroke Steering Committee (2011 to present)

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6. Member, Manitoba Cancer Partnership Steering Committee (2011 to present) University of Manitoba, Faculty of Medicine

1. Member, Manitoba Institute for Patient Safety, Board of Directors (June 2008 to June 2014)

2. Faculty representative, Manitoba Institute for Patient Safety, Standing Committee on Research (Member: June 2008 to present; Chair: August 2010 to June 2014)

Manitoba eHealth

1. Member, Provincial eHealth Strategic Advisory Council (April 2007 to present) 2. Member, eHealth Clinical Advisory Council, (March 2008 to present)

External Committees

1. Advisor – Streamlining Patient Flow from Primary to Specialty Care Project - Canadian Medical Association (October 2010 to present)

2. Member of the Health Care Task Force of the Manitoba Business Council (2004 to present)

3. Physician Assistant Development Foundation of Canada, Advisory Council (2008 to present)

COMMITTEES – Past University/ Hospitals

1. Intensive Care Monitoring Committee (Until July 1995) 2. Critical Care Task Force (Until July 1995) 3. Research Development Steering Committee, Health Sciences Center (1995) 4. H.S.C. Research Advisory Committee (1992-2001) 5. Intensive Care Nursing Program Coordinating Committee (Until 1995) 6. Intensive Care HA Planning Committee (until July 1995) 7. HA Planning Emergency Committee (design/planning of a new emergency wing

for the new hospital, until 1995) 8. Laboratory Utilization Committee (until July 1995) 9. Development of Transplant Surgery at the Health Sciences Centre (ad hoc).

Resulted in the development of the Lung Transplant Programme 10. Board Member, Health Sciences Centre Foundation (1992-2000) 11. H.S.C. Department of Research, Research Impact Committee 12. H.S.C. Spinal Cord Research Advisory Committee (Until 1994) 13. Research Advisory Committee (Until 2001) 14. Surgical Research Symposium Committee 15. General Surgery Post-graduate Committee 16. Faculty of Medicine Research Committee

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17. SERF (Surgical Education and Research Fund Committee) 18. R.O. Burrell Ad Hoc Committee 19. Department of Surgery Post-graduate Committee 20. Patent and Copyright Committee (U of M) 21. Directors Council, St. Boniface Hospital 22. Surgery Council, St. Boniface Hospital 23. Physician Assistant Steering Committee

Hospitals 1. Member, Medical Advisory Committee (1995 to 2006) 2. Member, Medical Directors Committee (1995 to 2006) 3. Member, WRHA Cardiac Sciences Regional Implementation Committee

(December 2006 to January 2007) 4. Co-Chair, Citywide Surgery Council 5. Chair, Citywide Subspecialty Council 6. Chair, Manitoba Telehealth Advisory Council, (2002 to 2007) 7. Member, Patient Flow Steering Committee (December 2006 to March 2008) 8. Member, Manitoba Transplant – Gift of Life Program (ODO) Advisory Board

(April 2006 to April 2007) 9. Member, Learning from Patient Experiences Steering Group (September 2006 to

2008) 10. Member, Pre-Habilitation Steering Committee (2005 to 2009) 11. Member, Quality Council (April 2006 to 2011) 12. Co-Chair, Integrated Community Systems Collaborative (2010 to 2011) 13. Member, eBooking Steering Committee (2010 to 2011) 14. Member, Innovation, Integration, and Information Council (2011) 15. Mentor, EXTRA Program for Kathleen Klassen, Dr. Paul Komenda and Sandra

Bowman (June 2011 to June 2013)

Winnipeg Regional Health Authority (WRHA) 1. Member, Regional Management Council (previously Senior Management) (April

2006 to present) 2. Member, Centre for Healthcare Innovation Committee (September 2006 to

present), 3. Member, MBTelehealth Provincial Strategy and Investment Committee (February

2007 to present) 4. Member, Family Physician Action Council (2008 to present) 5. Member, Standards Committee, WRHA (2009 to present) 6. Chair, Surgery Standards Committee, WRHA (2009 to present) 7. Member, Chronic Disease Collaborative Steering Committee (2009 to present) 8. Co-Chair – Generalist Specialist Collaboration Working Group, Provincial

Leadership Council (January 2013 to present)

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Manitoba Health

1. Member, Manitoba’s Approach to Primary Care Advisory Committee (2007) 2. Member, Wait Time Task Force Working Groups: Cancer, Cardiac, Diagnostic

Imaging, Orthopedics, Site Restoration, Pain Clinic, Sleep Testing & Treatment (May 2006 to 2008)

3. Member, Improving Efficiencies in Preoperative History and Physical Requirements Project – Steering Committee (2010)

University of Manitoba, Faculty of Medicine

1. Member, Faculty Tenure and Promotions Committee (2006, 2007) 2. Clinical Learning & Simulation Facility (CLSF) Implementation Committee 3. Co-Chair, Operations Committee of the Centre for Innovation (December 2006 to

2009) 4. Member, Dean’s Executive & ADMEG (September 2006 to June 2009) 5. Member, Dean’s Council (September 2006 to June 2009) 6. Dean’s representative, St. Boniface General Hospital, Medical Advisory

Committee (January 2007 to June 2009) 7. Dean’s representative, St. Boniface General Hospital, Patient Care Committee of

the Board (February 2007 to 2008) 8. Dean’s representative, Health Sciences Centre, Medical Advisory Committee

(January 2007 to June 2009) 9. Member, Department Heads Council (September 2006 to June 2009) 10. Member, Faculty Executive Council (Sept ember 2006 to June 2009) 11. Member, Faculty Council (September 2006 to June 2009) 12. Advisory Board Member, Manitoba Centre for Health Policy (as one of the

University of Manitoba representatives) (June 2008 to June 2011) Manitoba eHealth

1. Ex-officio, Manitoba Electronic Health Record Business Advisory Committee (2010 to 2011)

External Committees

1. Council of Critical Care Society - Royal College of Physicians and Surgeons 2. Council of the American Physiological Society 3. Scientific Review Committee - Canadian Critical Care Society 4. International Assistance Committee - Canadian Critical Care Society 5. Task Force on Provincial Research Directions sponsored by the Economic

Innovation and Technology Council of Manitoba. (Until January 1997) 6. Member of Steering Committee and Technical Advisory Group for the Western

Economic Diversification Pan-Western Clinical Trials Network. 7. Economic Innovation and Technology Council, Board Member, appointed 1995.

Resigned January 1997. 8. Member of the Board of Director, St. John’s Ravenscourt School (1997-2000).

Member of Executive, Governance Committees. Chair of Development

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Committee FUNDING 1978 - 1979 Faculty Fund 1979 - 1980 Medical Research Council

Faculty Fund (Establishment of Surgical Research Lab)

1980 - 1981 Medical Research Council Canadian Lung Association Medical Research Council (Fellowship - Dr. H. Unruh) 1981- 1982 Medical Research Council Manitoba Lung Association Myles Robinson Scholarship

Medical Research Council (Fellowship-Dr. R.Stimpson)

1982 - 1983 Medical Research Council Myles Robinson Scholarship Canadian Lung Association Canadian Heart Fdn (Association with Dr. L. Wood) Medical Research Council (Fellowship renewal - Dr. H.

Unruh) Lions Club of Manitoba (Development of Resuscitation Research)

1983 - 1985 Medical Research Council Canadian Heart Foundation Myles Robinson Scholarship Faculty Fund (Fellowship - Dr. S. Kowalski)

Canadian Lung Association (Fellowship-Dr. S. Kowalski) Manitoba Health Research Foundation (Fellowship-Dr. I.

Mayers) 1984 - 1985 Faculty Fund

(Fellowship - Dr. I. Mayers) Medical Research Council (1/2 yr Continuation of Fellowship Dr. R. Stimpson Sellers Foundation - Faculty Fund (Fellowship - W. Richardson) Myles Robinson Scholarship 1985 - 1988 Medical Research Council

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Canadian Heart Foundation Myles Robinson Scholarship 1989 Canadian Heart Foundation 1989-1992 Medical Research Council of Canada Heart & Stroke Foundation 1990-1991 Myles Robinson Scholarship 1990-1994 Myles Robinson Scholarship 1992-1994 Heart & Stroke Foundation 1992-1995 Medical Research Council of Canada 1993-1994 Manitoba Health Research Council Industrial Strategic Fund 1994 NRC (IRAP) in collaboration with Canamino Industries 1994- National Network of Centres of Excellence: Respiratory

Centre (Acute Lung Injury Project Leader, and Infrared Spectroscopy Imaging theme).

1995 Heart & Stroke Foundation 1995-1996 MHRC 1996 NCE - Inspiraplex (Lung Imaging Theme) 1996-1999 Baxter Healthcare Corp. Development of Blood Volume

Monitor. Development at the bench and clinical trials in the Central Dialysis Unit at HSC.

1996-2000 Gambro-Hospal Corp. New approaches to the treatment of pulmonary and brain edema

2009-2010 Dr. Paul H. T. Thorlakson Foundation Fund (Agent based and queuing models for healthcare re-engineering)

PUBLISHED ABSTRACTS

1. L. Oppenheimer, K. Craven, L. Forkert, and L.D.H. Wood. Pathophysiology of pulmonary contusion. Clin. Res., 24:692A, 1976.

2. K. Craven, L. Oppenheimer, and L.D.H. Wood. The pathophysiology of

pulmonary oxygen exchange in blunt chest trauma. Am. Rev. Res. Dis., 117:104, 1978.

3. L. Oppenheimer, V. Eling, and F. Lewis. Measurements of extravascular lung

water (EVLW) by thermal dye indicator dilution. Clin. Res., 27:1978.

4. H.S. Goldberg, W. Macedo, R. Graham, J. Rabson, and L. Oppenheimer.

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Dopamine (D) and Phentolamine (Phe) effect on lung vessels. Physiologist, 22(4), 1979.

5. R.M. Prewitt, L. Oppenheimer, H. Goldberg, J. Rabson, J. Sutherland, and L.D.H.

Wood. Does end systolic pressure (ESP) determine end systolic volume (ESV)? Physiologist, 22(4), 1979.

6. L. Oppenheimer, H. Goldberg, R. Holland, and W. Macedo. Filtration (Kf) and

reflection coefficients of pulmonary capillaries measured by indicator dilution: Validation in the isolated lobe. Physiologist, 22(4), 1979.

7. L. Oppenheimer and H. Goldberg. Transduction versus slow vascular

recruitment in the isolated lobe. Fed. Proc., 39(3):280, 1980.

8. R.M. Prewitt, L. Oppenheimer, J. Sutherland, and L.D.H. Wood. Acute effects of Nitroprusside on hemodynamic and oxygen exchange in patients with hypoxemic respiratory failure. Am. Rev. Resp. Dis., 121(4), April 1980.

9. L. Oppenheimer and H.S. Goldberg. Direct measurement of transduction across

the capillary membrane in the isolated lobe - Is it limited by tissue conductance? Clin. Res., October 1980.

10. H.W. Unruh, and L. Oppenheimer. Validation of thermal green dye

measurements of extravascular lung water (EVLW) in the isolated canine lobe. Physiol., October 1980.

11. L. Oppenheimer and H.S. Goldberg. Lung interstitial fluid redistribution

influences time course of transvascular fluid flux. Physiol., October 1980.

12. L. Oppenheimer, H. Unruh, H.S. Goldberg. Resistance to water flux in lung interstition. Fed. Proc., 40(3), 1981.

13. R. Graham, C. Skoog, L. Oppenheimer, and H.S. Goldberg. Critical closure of

lung vessels. Fed. Proc., 40(3), 1981.

14. J. Malo, R. Graham, L. Oppenheimer, and H.S. Goldberg. Canine vascular resistance and compliance in hypoxic hypoxia. Fed. Proc., 40(3), 1981.

15. G.R. Long, F.W. Santman, L. Oppenheimer, and L.D.H. Wood. Relative effects

of plasmapharesis (P), plasmapharesis plus vasoactive drugs and ultrafiltration on low pressure pulmonary edema in dogs. Physiologist, 24:55, 1981.

16. L. Oppenheimer, R.W. Prewitt, and L.D.H. Wood. Acute effect of PEEP on left

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ventricular mechanics in patients with hypoxemic respiratory failure. Presented at the Canadian Critical Care Society, October 1981.

17. R.W. Prewitt, L. Oppenheimer, and L.D.H. Wood. Acute effects of nitroprusside

inpatients with hypoxemic respiratory failure. Presented at the Canadian Critical Care Society, October 1981.

18. P.H. Breen, P.T. Schumacker, J. Sandoval, I. Mayers, L. Oppenheimer, and

L.D.H. Wood. Does increased cardiac output increase shunt by increasing pulmonary ? Fed. Proc., 41(4):995, 1982.

19. I. Mayers, J. Sandoval, P.H. Breen, L.D.H. Wood, and L. Oppenheimer. The

effect of high frequency oscillatory ventilation (HFOV) on extravascular lung water (EVLW). Fed Proc., 41(4):1247, 1982.

20. J. Sandoval, I. Mayers, P. Breen, L. Oppenheimer, and L.D.H. Wood. Relative

effects of high frequency oscillatory ventilation and continuous positive pressure ventilation on hemodynamics, gas exchange, and extravascular lung water. Am. Rev. of Resp. Dis., 125(4):85, 1982.

21. R. Stimpson, C. Skoog, H. Goldberg, and L. Oppenheimer. Transpulmonary

pressure influences tissue impedance to edema formation. Fed. Proc., 41(4):1361, 1982.

22. J. Sandoval, G.R. Long, C. Skoog, L.D.H. Wood, and L. Oppenheimer.

Independent influence of blood flow rate and mixed venous Po2 on shunt fraction

in an isolated perfused dog lung. Can. Soc. for Clin. Invest., 1982.

23. R. Stimpson, I. Mayers, and L. Oppenheimer. Hysteresis in resolution of pulmonary edema. Can. Soc. for Clin. Invest., 1982.

24. G.R. Long, J. Sandoval, C. Skoog, L.D.H. Wood, and L. Oppenheimer. Influence

of flow and mixed venous Po2 on shunt fraction and pressure flow relationships

in isolated canine lobes. Fed. Proc., 42(3):491, 1983.

25. M.E. Arnup, H.W. Greville, L. Oppenheimer, N.R. Anthonisen. Dynamic function of lungs with compensatory growth. Fed. Proc., 42(4):1009, 1983.

26. L. Oppenheimer, I. Mayers, R. Stimpson, and C. Skoog. Time course of high

pressure edema resolution. Fed. Proc., 42(4):1006, 1983.

27. L. Oppenheimer. Pulmonary tissue properties influence the rate of transvascular flux. Presented at the XXIX World Congress of Physiological Sciences, Sydney,

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Australia, August 1983.

28. H.W. Greville, M.E. Arnup, S.N. Mink, L. Oppenheimer and N.R. Anthonisen. Maximum expiratory flow reduction in pneumonectomized dogs. Fed. Proc. 43(3):435, 1984.

29. S. Kowalski, C. Skoog and L. Oppenheimer. Effects of airway pressure volume

relationship on pulmonary interstitial mechanics. Fed. Proc., 43(4):1033, 1984.

30. L. Oppenheimer and H.W. Unruh. Changes in tissue properties cause hysteresis in edema resolution. Fed. Proc., 43(4):1033, 1984.

31. S. Mink, H. Unruh and L. Oppenheimer. Vascular and interstitial mechanics in

canine pulmonary emphysema. Am. Rev. Resp. Dis., April, 1985.

32. J. Ali, K. Duke, L. Oppenheimer. Decreased wedge pressure does not uniformly decrease pulmonary edema. Am. Rev. Resp. Dis., 131(4):A147, April 1985.

33. I. Mayers, D. Bilan, J. Wilson and L. Oppenheimer. Colorimetric determination of

pulmonary capillary reflection coefficient to albumin. Fed. Proc., 44(6):1904, March 1985.

34. S. Kowalski, I. Mayers, and L. Oppenheimer. Interstitial fluid trapping with lung

recoil. Fed. Proc., 44(6):1904, March 1985.

35. S. Kowalski, A. Downs, C. Lye and L. Oppenheimer. Extravascular lung water during aortic cross clamping. Presented at the Canadian Anesthetists' Society Meeting, 1985.

36. W. Richardson, M. Hoppensack, D. Bilan and L. Oppenheimer. Transvascular

fast fluid flux or Fahraeus effect? Fed. Proc., 45(3):283, 1986.

37. L. Oppenheimer, D. Bilan, W. Richardson and M. Hoppensack. Colorimetric measurement of fluid flux in blood. Fed. Proc., 45(3):283, 1986.

38. L. Oppenheimer. Manipulation of tissue forces in the treatment of patients with

ARDS. Can. Crit. Care Soc., October 1986.

39. W.N. Richardson, D. Bilan, M. Hoppensack, and L. Oppenheimer. Transvascular Fluid flux or Fahraeus effect? Can. Soc. for Clin. Invest., October 1986.

40. W.N. Richardson, D. Bilan, and L. Oppenheimer. Influence of circuit parameters

on exponential time-course of weight change in isolated dog lobes. FASEB,

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46(4):4576, April 1987.

41. L. Oppenheimer. Pulmonary capillary effective filtration pressure from occlusion pressure profile in humans. Can. Soc. Clin. Invest., September 1987.

42. W.N. Richardson and L. Oppenheimer. Effect of vascular change on the time

course of slow weight gain in isolated dog lobes. Can. Soc. Clin. Invest., September 1987.

43. S.G. Holtby, S.N. Mink, L. Oppenheimer, D.J. Berezanski, and N.R. Anthonisen.

Lobar emptying sequence affects maximum expiratory flow in dogs with compensatory lung growth. Clin. Invest. Med., B121, 1987.

44. L. Oppenheimer, B.J. Hancock, and M. Hoppensack. Role of slow vascular

changes on determinations of transvascular fluid flux. Federation Proceedings, May 1988.

45. B.J. Hancock, M. Hoppensack, and L. Oppenheimer. Do transvascular forces in

the lung ever equilibrate? FASEB, 2(6):8163, May 1988.

46. S. Kowalski, G. Dobson, M. Hoppensack and L. Oppenheimer. The distribution of pulmonary vascular resistance: Effects of hypoxia and halothane. Presented at the American Society of Anesthesiologists' Meeting. San Francisco, 1988.

47. L. Oppenheimer, B.J. Hancock and M. Hoppensack. Role of slow vascular

changes on determinations of transvascular fluid flux. FASEB, 2(5):5797, May 1988.

48. M. Younes, D. Roberts, R.B. Light, L. Oppenheimer, R. Long, K. Taylor, H.

Cramp and A. Puddy. Proportional assist ventilation (PAV), a new approach to ventilatory support. Am. Rev. Resp. Dis, 139, 40:A363, April, 1989.

49. K. Landolfo, M. Hoppensack and L. Oppenheimer. Slow lobar transvascular

exchange reviewed. FASEB, 3(4):5307, March, 1989.

50. G. Dobson, S. Kowalski, M. Hoppensack and L. Oppenheimer. Pulmonary artery occlusion breakpoint pressure accurately approximates pulmonary double occlusion pressure. FASEB, 3(4):5436, March, 1989.

51. S. Holtby, D. Georgopoulos, A. Gomez, L. Oppenheimer, D. Berezanski, N.R.

Anthonisen, S. Mink. Nonhomogeneity of lobar emptying during forced deflation in a canine model of compensatory lung growth. FASEB, 3(4):6251, March, 1989.

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52. R.B. Light, M. Younes, D. Roberts, L. Oppenheimer, R. Long, K. Taylor, H.

Cramp and A. Puddy. Effect of proportional assist ventilation (PAV) on gas exchange, ventilation and patient comfort in ventilator-dependent patients with hypoxemic respiratory failure. Royal College of Physicians & Surgeons, September, 1989.

53. K.P. Landolfo and L. Oppenheimer. Which is the downstream pressure to

transvascular fluid flux. FASEB, 4(3):A411:830, April 1990.

54. L. Oppenheimer, M.E. Furuya and K.P. Landolfo. Influence of lobar height on transvascular fluid flux. FASEB, 4(3):A410:831, April, 1990.

55. A.Puddy, M. Younes, D. Roberts, L. Oppenheimer, R. Long, K. Taylor, H. Cramp

and R. Light. Ventilatory support with proportional assist ventilation (PAV). The Thoracic Society of Australia and New Zealand, April 1990.

56. D. Georgopoulous, L. Oppenheimer, N.R. Anthonisen and S. Mink. How is

maximal expiratory flow (Vmas) reduced in post-pneumonectomy (PP) lung growth in dogs? FASEB, 4(3):A228:126, April, 1990.

57. K.P. Landolfo and L. Oppenheimer. Resolution of low pressure pulmonary

edema with an osmotic agent. Am. Rev. Resp. Dis., 141, 4:A296, April, 1990.

58. L. Oppenheimer and K.P. Landolfo. A laser colorimetry technique to measure transvascular fluid flux. Am. Rev. Resp. Dis., 141, 4:A296, April, 1990.

59. M.E. Furuya and L. Oppenheimer. On-line spectrophotometric determination of

drag reflection coefficient in isolated lobes. FASEB, 5(6):A1730, May, 1991.

60. L. Oppenheimer and M.E. Furuya. Influence of non-convective protein transport on filtration coefficient and force balance in isolated lobes. FASEB, 5(6):A1731, May, 1991.

61. D. Bell and L. Oppenheimer. Direct measurement of transvascular fluid

exchange in intact lungs. FASEB, 5(6):A1731, May, 1991.

62. S. Marantz, K. Webster, W. Patrick, D. Roberts, L. Oppenheimer and M. Younes. Respiratory responses to different levels of proportional assist (PAV) in ventilator dependent patients. American Review of Respiratory Diseases, 145(4):A525, 1992.

63. A. Palomar, R.B. Light, D. Bell, A. Smit and L. Oppenheimer. Treatment of low

pressure pulmonary edema in dogs with Hetastarch. American Review of

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Respiratory Diseases; 145(4):A525, 1992.

64. A. Smit, A. Palomar and L. Oppenheimer. On-line spectrophotometry combined with gel filtration chromatography in the analysis of transvascular macromolecular transport. FASEB, 6(4):A1536:3472, April, 1992.

65. A. Palomar, A. Smit and L. Oppenheimer. On-line spectrophotometric analysis of

albumin and dextran 500 transport. FASEB, 6(4):A1536:3473, April, 1992.

66. A. Smit, A. Palomar and L. Oppenheimer. Effect of Increased Fluid and Solute Exchange Measured with an On-Line Spectrophotometer. FASEB, 7(3):1354:A234, April, 1993.

67. W. Patrick, K. Webster, P. Wiebe, D. Roberts, R.B. Light, L. Oppenheimer, L.

Ludwig and M. Younes. The use of proportional assist ventilation to avoid intubation in patients with acute respiratory failure. Amer. Rev. Resp. Dis., 147(4):A984, 1993.

68. W. Patrick, K. Webster, P. Wiebe, D. Roberts, R.B. Light, L. Oppenheimer, D.

Kassum and M. Younes. Effect of proportional assist ventilation on the hemodynamics of patients in septic shock. Amer. Rev. Resp. Dis., 147(4):A611, 1993.

69. P. McMillan, S. Kowalski, L. Oppenheimer and D. Roberts. Patients undergoing

major vascular surgery do not require automatic ICU admission. Presented at the Royal College of Physicians and Surgeons Meeting, Vancouver, B.C., September 1993.

70. P. Tauriainen and L. Oppenheimer. Changes in pleural pressure affect fluid

filtration in isolated lobes. FASEB, 8(4):2396:A414, April, 1994.

71. A. Smit and L. Oppenheimer. Human serum albumin attenuates pressure induced vascular change in the isolated perfused canine lung. FASEB,. 8(4):2399:A414, April, 1994

72. P. Fata, R. Stimpson and L. Oppenheimer. A new approach to the treatment of

ARDS with macromolecular solutions. Experimental approach. Proceedings of International Society of Critical Care. December 1999

73. P. Fata, R. Stimpson and L. Oppenheimer, A new approach to the treatment of

ARDS with macromolecular solutions. Clinical study. Proceedings of International Society of Critical Care. December, 1999

74. C. Carrick, T.Y. ElMekkawy, L. Oppenheimer, L. Ghobrial-Zaki, B. DeMone.

Decision Support to Facilitate the Process of Referral within an Online Referral

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System. March 2012

75. C. Carrick, T.Y. ElMekkawy, L. Oppenheimer, Walter Balestra, L. Ghobrial-Zaki, B. DeMone. Comparative Study of Two Similar, Independently Developed Electronic Referral Systems

PUBLICATIONS PUBLISHED ARTICLES AND BOOK CHAPTERS:

1. L. Oppenheimer, B.W. Hryniuk, and A. Bishop. Thrombocytopenia in severe bacterial infections. J. Surg. Res., 28(3):211, 1976.

2. L. Oppenheimer, K. Craven, L. Forkert, and L.D.H. Wood. Pathophysiology of

pulmonary contusion in dogs. J. Appl. Physiol., 47(4):718-728, 1979.

3. K. Craven, L. Oppenheimer, and L.D.H. Wood. Effects of contusion and flail chest on pulmonary perfusion and oxygen exchange. J. Appl. Physiol., Resp. Environ. Exercise Physiol., 47(4):729-737, 1979.

4. L. Oppenheimer, V. Eling, and F. Lewis. Effects of diffused embolization in

pulmonary extra-vascular water measured by thermal green dye indicator dilution. J. Surg. Res., 26:504, 1979.

5. C. Baker, L. Oppenheimer, F.R. Lewis, and D.T. Trunkey. Epidemiology of

trauma deaths. Am. J. of Surg., July 1980.

6. R.M. Prewitt, L. Oppenheimer, J.B. Sutherland, G.W. Dean, R. Palser, and L.D.H. Wood. The effects of positive and expiratory pressure on left ventricular mechanics in patients with hypoxemic respiratory failure. Anaesthesiology, October 1981.

7. L. Oppenheimer, L.D.H. Wood and R.M. Prewitt. Acute effects of Nitroprusside

in patients with hypoxemic respiratory failure. Surg. Forum., 32:306, 1981.

8. L. Oppenheimer, C.M. Burns. Pathophysiology of lung contusion. Med.in North America, Vol. 23, May 1982.

9. R. Graham, C. Skoog, L. Oppenheimer, and H.S. Goldberg. Critical closure in

the pulmonary vascular bed. Cir. Res. 50(4):566-572, 1982.

10. L. Oppenheimer. New approaches to the measurement of pulmonary capillary permeability and pulmonary edema. Can. J. of Surgery, 25(4): 418-421, 1982.

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11. L. Oppenheimer, H.W. Unruh, C. Skoog, and H.S. Goldberg. Transvascular fluid

flux measured from intravascular water concentration changes. J. Appl. Physiol., 54(1):64-72, 1983.

12. R. Graham, W. Macedo, C. Skoog, J. Carter, L. Oppenheimer, J. Rabson, and

H.S.. Goldberg. Dopamine, Dobutamine and Phetolamine. Effects on pulmonary vascular bed. J. Appl. Physiol. : Respirat. Environ. Exercise Physiol., 54(5):1277-83, 1983.

13. L. Oppenheimer. Pulmonary tissue properties influence the rate of transvascular

fluid flux. Proceedings of the XXIX World Congress of Physiological Sciences, Sydney, Australia, August 1983.

14. J. Sandoval, R. Long, C. Skoog, L.D.H. Wood, and L. Oppenheimer.

Independent influence of blood flow rate and mixed venous Po2 on shunt

fraction. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol., 55(4):1128-1133, 1983.

15. H.W. Unruh, H.S. Goldberg, L. Oppenheimer. Pulmonary interstitial

compartments and tissue resistance to fluid flux. J. of Appl. Physiol., 57(5): 1512-1519, 1984.

16. M.E. Arnup, H.W. Greville, L. Oppenheimer, S.N. Mink, and N.R. Anthonisen.

Dynamic lung function in dogs with compensatory lung growth. J. Appl. Physiol., 57(5):1569-1576, 1984.

17. Pulmonary interstitium and edema. Chapter in current concepts in adult

respiratory distress syndrome. Published by Zapol, Lemare and Artigas., Churchill Publishers, 1984.

18. S.N. Mink, H.W. Unruh and L. Oppenheimer. Vascular and interstitial mechanics

in canine pulmonary emphysema. J. Appl. Physiol., 59(6):1704-1715, 1985.

19. P.H. Breen, P.T. Schumacker, J. Sandoval, I. Mayers, L. Oppenheimer and L.D.H. Wood. Increased cardiac output increases shunt: role of pulmonary edema and perfusion. J. Appl. Physiol., 59(4):1313-1321, 1985.

20. L. Oppenheimer. Manipulation of tissue forces in the treatment of low pressure

edema. Can. Jrnl. of Surg., 28(4): 326-328, July 1985.

21. H.W. Greville, M.E. Arnup, S.N. Mink, L. Oppenheimer and N.R. Anthonisen. Mechanism of reduced maximum expiratory flow in dogs with compensatory lung

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growth. J. Appl. Physiol., 60(2):441-448, 1986.

22. L. Oppenheimer, W.N. Richardson, D. Bilan and M. Hoppensack. A Colorimetric device for the measurement of transvascular fluid flux in blood perfused organs. J. Appl. Physiol., 62(1):364-372, 1987.

23. S.N. Mink, S.G. Holtby, D.J. Berezanski, L. Oppenheimer and N.R. Anthonisen.

Heterogeneity of maximal lobar emptying rates in dogs with compensatory lung growth. J. Appl. Physiol., 67(3):1164-1170, 1989.

24. L. Oppenheimer, and H.S. Goldberg. The pulmonary circulation and interstitial

edema in heart & lung interactions. Edited by S. Cassidy and S.M. Shariff, Marcel Dekker, New York, 1989.

25. L. Oppenheimer. Re-evaluation of Starling Forces balance and lymphatic

clearance in the lung. Update in Intensive Care and Emergency Medicine, Edited by J.L. Vincent, Springer-Verlag, p. 58, 1989.

26. S. Kowalski, A.R. Downs, C. Lye and L. Oppenheimer. Measurement of extra-

vascular lung water during abdominal aortic surgery. Can J. Anaesth., 33(3):283-8, 1989.

27. B.J. Hancock, M. Hoppensack and L. Oppenheimer. Do transvascular forces in

isolated lobe preparations equilibrate? J. Appl. Physiol., 67(2):628-635, 1989.

28. H. Unruh, M. Hoppensack, L. Oppenheimer. Vascular properties of canine lungs perfused with Eurocollins' Solution and Prostacyclin. Ann Thorac Surg, 49:292-298, 1990.

29. L. Oppenheimer. Lung fluid movement and its relevance to the management of

patients with increased lung water. Clinical Intensive Care, International Journal of Critical & Coronary Care Medicine, 1(3):103-110, 1990.

30. L. Oppenheimer, E. Furuya, K.P. Landolfo and D. Huebert. Line Colorimetric

Determinations of Transvascular Fluid and Protein Transport in Isolated Lobes. Respiratory Biomechanics. Edited by Mary A. Farrell Epstein and James R. Ligas, Springer-Verlag, P. 169-175, May 1990.

31. A. Puddy, M. Younes, D. Roberts, L. Oppenheimer, R. Long, K. Taylor, H. Cramp

and R. Light. Ventilatory support with proportional assist ventilation (PAV). Australian & New Zealand Journal of Medicine, 20(3):524, June 1990.

32. B.J. Hancock, K.P. Landolfo, M. Hoppensack and L. Oppenheimer. Slow phase

of transvascular fluid flux reviewed. J. Appl. Physiol., 69(2):456-464, August,

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1990.

33. D. Georgopoulous, S.N. Mink, L. Oppenheimer and N.R. Anthonisen. How is maximal expiratory flow reduced in canine post-pneumonectomy lung growth? J. Appl. Physiol., 71(3):834-840, 1991.

34. L. Oppenheimer. Cardiopulmonary Interactions. Archives Bronchopneumology,

Vol 27, Number 7, October, 1991. Barcelona, Spain.

35. D. Georgopoulos, S.N. Mink, L. Oppenheimer and N.R. Anthonisen. How is maximal expiratory flow reduced in canine post-pneumonectomy lung growth? J. Appl, Physiol. 71(3):834-840, 1991.

36. M. Younes, A. Puddy, D. Roberts, R.B. Light, A. Quesada, K. Taylor, L

Oppenheimer and H. Cramp. Proportional Assist Ventilation II. Amer. Rev. Resp. Dis. 145:121-129, 1992.

37. M. Younes, A. Puddy, D. Roberts, R.B. Light, A. Quesada, K. Taylor, L.

Oppenheimer, and H. Cramp. Proportional Assist Ventilation: Results on an initial clinical trial. Amer. Rev. Resp. Dis. 145:372-376, 1992.

38. Canadians for Health Research: A Salute to Excellence. Chapter entitled,

"Advances in the Treatment of Pulmonary Edema", published by CHR, Ottawa, Canada, April, 1992.

39. Adult Respiratory Distress Syndrome. Published by Artigas, Lemare, Suter and

Zapol. Churchill Livingstone, 1992.

40. Plasma Volume Expansion. Chapter on re-evaluation of Starling force balance. Edited by Jean-François Baron, Arnette Publishers, Paris, 1992.

41. L. Oppenheimer, D. Huebert. Near Infra-Red Spectrophotometric Device to

Measure Fluid Exchange in Blood Perfused Organs. Journal of Applied Physiology, 74(5):2205-2213, May 1993.

42. S. Marantz, W. Partrick, K. Webster, D. Roberts, L. Oppenheimer and M.

Younes. Response of ventilator dependent patients to different levels of proportional assist (PAV). Journal of Applied Physiology, 80(2):397-403, 1996.

43. W. Patrick, K. Webster, P. Wiebe, D. Roberts, B. Light, L. Oppenheimer, D.

Kassum and M. Younes. Effect of Proportional Assist Ventilation on the Hemodynamics of Patients in Septic Shock. 1993 ALA/ATS International Conference, May 16-19, 1993. San Francisco, California.

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44. P. McMillan, L. Oppenheimer, D. Roberts and S. Kowalski. Patients Undergoing

Major Vascular Surgery Do Not Require Automatic ICU Admission. Royal College of Physicians and Surgeons, Vancouver, September 10-13, 1993.

45. D. Roberts, D. Bell, T. Ostryzniuk, K. Dobson, L. Oppenheimer, D. Martens, N.

Honcharik, H. Cramp, E. Loewen, S. Bodnar, A. Guenther, L. Pronger, E. Roberts, and T. McEwen. Eliminating needless testing in intensive care - An information-based team management approach. 1993, Critical Care Medicine.

46. L. Oppenheimer. A unifying theory to explain transvascular fluid and

macromolecular exchange in lungs and in general. Clinical applications. PhD Dissertation, Proceedings of the Faculty of Medicine, University of Barcelona, 1994.

47. Pulmonary Edema Reabsorption: New Therapeutic Strategies. Published in the

Volume, Pulmonary Circulation: Moving from Passive to Active Control. Edited by M.R. Pinsky, J.F. Dhainaut and A. Artigas. 271-281. WB Saunders Company Ltd. 1996

48. Oedeme pulmonaire et mouvement de liquides(47-52) Ed. A. Tenaillon et A.

Artigas Reanimation. Insufficances Respiratoires Aigues. 1998.

49. Treatment of Non-Cardiogenic Pulmonary Edema. In Oxford Textbook of Critical Care. 272-275. Edited by A.R. Webb, M.J. Shapiro, M. Singer and P.M. Suter. Oxford University Press. 1999

50. R. Neighbour, L. Oppenheimer, S. Mukhi, M. Friesen and R.D. McLeod. Agent

Based Modeling of “Crowdinforming” as a Means of Load Balancing at Emergency Departments”, Online Journal of Public Health Informatics, Vol.2, No. 3, 2010

51. Curtis Carrick; Luis Oppenheimer; Walter Balestra; Tarek Y ElMekkawy.

Comparative Study of Two Similar, Independently Developed E-Referral Programs. International Journal of Medical Informatics. 2012

52. Cui Yang, Colleen Metge, Xibiao Ye, Michael Moffatt, Luis Oppenheimer and

Evelyn Forget.- Development and validation of a predictive model for all-cause hospital readmissions in Winnipeg, Canada.- Journal of Health Services Research & Policy 2015, Vol. 20: 83-91.

53. L. Loucks, E. Bohm, K, Wittmeier, L. Lix and L. Oppenheimer.- Reduced Time to

Surgery Improves Mortality and Legth of Stay Following Hip Fracture: Results from and Intervention Study in a Canadian Health Authority. – Accepted for Publication.- Canadian Journal of Surgery. March, 2015.

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27

PATENTS

Edema Management System British Preliminary Applications

Filed, March 1992

On-line Devices to Monitor Blood Parameters British Preliminary Applications

Filed, March 1992

Treatment of Permeability Pulmonary Edema with Macromolecular Solutions British Preliminary Applications

Filed, March 1992

SPECTROPHOTOMETRIC BLOOD ANALYSIS I: L. Oppenheimer. U.S. Patent number 5,331,958. Issued Jul. 26, 1994.

SPECTROPHOTOMETRIC BLOOD ANALYSIS II: L. Oppenheimer. U.S. Patent

number 5,601,080. Issued Feb. 11, 1997.

Lung Permeability Analysis, Filed, September 21/95. U.S. patent Granted, July 1999 (withdrawn)

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SUPERVISION OF GRADUATE STUDIES SINCE 1978 Helmut Unruh, M.D. Don Petkau, M.D. Ross Stimpson, M.D. Richard Long M.D. Doug Ankrom, B.Sc. (Thesis) Julio Sandoval, M.D. Stephen Kowalski, M.D. Irvin Mayers, M.D. Paul Schumacker, Ph.D. Peter Breen, M.D. William Richardson, M.D. Zhen-rong Guo, M.D. Joel Kettner, M.D. Maria E. Furuya, M.D. Betty-Jean Hanock, M.D., M.Sc. (Thesis) Andres Palomar, M.D. Kevin Landolfo, M.D., M.Sc. (Thesis) Peter Tauriainen, M.D. Dean Bell, M.D. Julio Pinton, M.D. Arno Smit, DVM, M.D. PhD. candidate John Bracken, M.D. J. Wang M.Sc. (PhD Thesis) P. Fata, M.D. D. Davidson, M.D. Elham Sadeh, BHSA., M.Sc. Curtis Carrick, B.Sc. Mechanical Engineering