The Laboratory for Product Design, Development &

Evaluation

The LPD2E provides a network of expert resources and capabilities that spans the spectrum from fundamental research concepts and the initiation of new formulations and their production paradigms, to providing GMP-compliant products for related clinical investigations and patient trials. Any component or mix of components from these collaborations could be brought to bear on problems which may be of interest to the private sector.

Besides basic research activities, collaborations could involve any type of ‘needs assessments’ and/or contractual arrangements that could be geared toward the advancement of specific technologies. Collaborations might include assisting small companies that can benefit from LPD2E’s expertise or capability in navigating the development stages of a project. Likewise, larger companies, having considerable resources already engaged in multi-project scenarios, might desire interactions for exploratory high-risk research projects or to develop potential spin-off areas without the need for internal corporate resources. Similarly, broad and/or specific interactions with either large or small businesses might be envisioned to simply tap the intellectual diversity afforded by the LPD2E network in order to gain different perspectives at any stage of product design and development.

The Laboratory for Product Design, Development & Evaluation (LPD2E) was

established in January 2011 as a component of the research and

teaching infrastructure within The University of Toledo College of

Pharmacy & Pharmaceutical Sciences (UTCPPS). The GMP-

compliant Core Laboratories operate within the Industrial

Pharmacy Division of the Department of Pharmacy Practice.

THE LABORATORY FOR PRODUCT DESIGN, DEVELOPMENT & EVALUATION

C o n t a c t L P D 2 E The University of Toledo College of Pharmacy and Pharmaceutical Sciences Laboratory for Product Design, Development and Evaluation 3000 Arlington Ave Toledo, OH 43614 Phones: 419.383.1988 ; 419.383.1990; 419.383.1981 FAX: 419.383.1950 www.utoledo.edu/pharmacy/depts

General Capabilities

• Solubility enhancement of poorly soluble drugs

• Flavor masking

• Nanoparticle drug delivery

• Microemulsion drug delivery

• Dematological drug delivery

• Placebo tablet & capsule production

• API clinical trial production

Evaluative Capabilities

• Dissolution testing- tablets, capsules, and ointments

• Powder characterization

• Product stability determination

• Taste testing panels

• Ingredient compatibility testing

Analytical Capabilities

• UV-Vis spectrophotometer

• Surface tension analysis

• Viscosity determination

• TGA-DSC-TMA analysis

• Dynamic light scattering

• PXRD

• FTIR

• Scanning electron microscopy

• Fluorescence analysis

• Moisture determination

• HPLC analysis

Manufacturing Equipment

• Tablet machines (3)

• Ointment mills

• Homogenizers

• Lipstick and suppository fillers

• Solution mixing and filtering

• Ointment filler

Product Design and Development

• Oral and topical solutions

• Suspensions

• Emulsions

• Dermatologicals

• Capsule formulations

• Tablet formulations

• Extended release formulations

• Parenteral products

• Ophthalmic products

• Effervescent powders and tablets

• Cosmetics

• Personal care products

• Toothpaste