Life Science, what?Products which serve human health careProduct’s source is Asian herbal traditional

medicineHerbs extractThe extract is marketed to end-stage

companies in the pharmaceutical, cosmetic or food supplement market

unique technology

Products95% pure extract from the leaves of the

Ginkgo biloba tree; GinkgoTerp®R&D:

Immune stimulatorsAnti-oxidizing agentsAnticancer steroïds

GinkgoTerp®Because of the different constituents, this extract

can affect various systems in the human bodyIn general, GinkgoTerp® is a perfect prophylaxis

for the body under strain or where the body is decreasingly able to recover from it, such asSportsStressAgeing

Atherosclerosis Memory impairment Alzheimer’s disease Parkinson’s disease

Bioactivity: flavonoïds and terpenelactonesFlavonoïds are free-radical scavengers. Since

flavonoïds are also available in dietary products, the additional effect of the amount in the normal extract is considered to be not significant.

Terpene trilactones are known to block three receptors (GABA -, Glycine – and Platelet Activating Factor receptors) and act on mitochondria throughout the whole body. Effects of GBE are largely attributed to these compounds

Mode of actionAlzheimer’s diseaseParkinson’s diseaseMood/anxietyCancer progression

Cognitive functionNeuronal damage

CardiovascularAtherosclerosisErectile dysfunction

GABA

GLY

PAFGk A+B

GkB

Bil

BilGkA

mito

chon

dr

ia

Disappointing results of Ginkgo studiesGinkgo shows a clear positive effect on vascular

disorders with 240mg a dayIntermittent claudationVascular dementia

No positive results from clinical studies regarding Alzheimer’s diseaseAn inadequate dosage regimen could be the cause

Estimation of the correct dosage regimen is a must!

Dosage regimen(1)Tablets/capsules have to be taken 0.5h

before the meal to obtain a desired blood-level

Tablets/ capsules have to be taken at two or three different time points per day

Tablets/capsules have to be non-enteric coated

Dosage regimen(2)Based on the pharmacology of the active constituents, following doses are advised:

vascular disorders: 120/7.5 mg, twice a day*memory impairment: 240/15 mg, twice a day*neurodegenerative diseases: 360/22.5 mg, thrice a

day*

* EGb761/GinkgoTerp®

GinkgoTerp® vs. EGb76195%

terpenelactonesNO flavonoids5% undefined7.5 mg extract to

achieve effect

6% terpenelactones

24% flavonoids70% undefined120 mg extract to

achieve effect16 times less

Why are we the best?Competitors produce a 30% pure product,

GinkgoTerp® is a 95% pure product of the active compounds

Based on terpenelactones-content, we produce 16 times purer extract than competitors

bilobalide

ginkgolides

flavonoidglycosides

variable and/or to bedetermined

SGBE-T

49%45%

5%1%bilobalide

ginkgolides

flavonoidglycosides

variable and/or to bedetermined

GinkgoTerp®

EGB 761

24%

70%

3%3%

Competitors

Co-formulationsSince GinkoTerp® is added in much less mg’s as

competitive extracts, co-formulation is an excellent option

For instance with:Sports: Magnesium, Potassium, ZincStress/Concentration: Vitamin B1 and 3Ageing: Vitamins (B1,3,9, C, E)

Principle of productionExcellent quality of raw material

continuity, method of harvesting and drying

A unique production process for extract with high purity level

What’s in it for you?A 16x purer extract/new formula means:You get your money’s worth

95% instead of 6% terpenelactones-content

Competitive price setting which creates a win-win situation

Less side effectsless undefined compounds, 5% vs. 70% undefined

Smaller dose needed in formulation 16 times less mg’s needed e.g. 7.5mg GinkgoTerp® vs. 120mg EGb761

Increasing convenience for consumersmaller tablets/capsules; easier to swallow

Excellent to use in co-formulations16 times less mg’s needed

No colorizationsnow-white appearance