lid lag 4-3. von graefe sign persistent elevation of the upper lid on downgaze lid lag

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Lid Lag 4-3

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Page 1: Lid Lag 4-3. Von Graefe Sign Persistent elevation of the upper lid on downgaze Lid Lag

Lid Lag4-3

Page 2: Lid Lag 4-3. Von Graefe Sign Persistent elevation of the upper lid on downgaze Lid Lag

Von Graefe Sign

Persistent elevation of the upper lid on downgaze

Lid Lag

Page 3: Lid Lag 4-3. Von Graefe Sign Persistent elevation of the upper lid on downgaze Lid Lag

Classical Signs: TAO

A prominent stare.

Retraction of all four eyelids

Bilateral exophthalmos

Hertel exophthalmometer 25 OD, 28 OS, base 108.

Tight orbits/reduced orbital resilience

Prominent congested scleral blood vessels

A visible rim of sclera on gentle eye closure

Page 4: Lid Lag 4-3. Von Graefe Sign Persistent elevation of the upper lid on downgaze Lid Lag

Eye Movements

Lid lag (persistent elevation of the upper eyelid in downgaze) – von Graefe sign

Marked limitation of upward gaze

Mild limitation of downgaze

Restricted horizontal eye movements

Positive forced duction test

Page 5: Lid Lag 4-3. Von Graefe Sign Persistent elevation of the upper lid on downgaze Lid Lag

Limitation of upgaze is due to tethering of the eyeball in the floor of the orbit by soft tissue changes.

Tethering of the eyeball inferiorly can be confirmed by a forced duction test.

Limited Upgaze

Page 6: Lid Lag 4-3. Von Graefe Sign Persistent elevation of the upper lid on downgaze Lid Lag

Limited Upgaze Duction Test

1. Anesthetize the eye with topical anesthesia2. Push on the globe with a cotton tip3. Pull with blunt tweezers to try to move

eye up.

Mechanical restriction - a positive forced duction test.

Page 7: Lid Lag 4-3. Von Graefe Sign Persistent elevation of the upper lid on downgaze Lid Lag

Most serious complication

Crowding of the orbital apex by enlarged ocular muscles

Present in 50% severe cases TAO

May require urgent orbital decompression

Compressive Optic Neuropathy

Page 8: Lid Lag 4-3. Von Graefe Sign Persistent elevation of the upper lid on downgaze Lid Lag

Figure 1 Axial CT through the orbit without contrast shows enlargement of the medial rectus muscle bilaterally. Note that the tendinous insertion is spared.

Page 9: Lid Lag 4-3. Von Graefe Sign Persistent elevation of the upper lid on downgaze Lid Lag

Figure 2 The coronal CT (reformatted from axial data set) without contrast shows enlargement of the medial rectus muscle, inferior rectus muscle and upper muscle complex on both sides. Courtesy of Hugh Curtin, M.D.

Page 10: Lid Lag 4-3. Von Graefe Sign Persistent elevation of the upper lid on downgaze Lid Lag

http://www.library.med.utah.edu/NOVEL