#SpayTogether is a stimulus fund administered by The Humane Society of the United States that providessurgery support grants, on-ground assistance, training in high-quality/high-volume spay and neuter procedures and discounted veterinary supplies and services to shelters and clinics affected by COVID-19.

Let’s #SpayTogether:Special offers from Covetrus

Promotion Details Expires

ParaDefense Advanced for Dogs

Buy 6 trays (1 case) of ParaDefense Advanced for Dogs, get 2 trays at no charge.Mix and match. Must be purchased on a single invoice. Limit 10 promotional orders per customer. Cannot be combined with any other offers.

09/30/2020

ParaDefense for Cats

Buy 6 trays (1 case) of ParaDefense for Cats, get 2 trays at no charge.Mix and match. Must be purchased on a single invoice. Limit 10 promotional orders per customer. Cannot be combined with any other offers.

09/30/2020

Elanco vaccinesNEW ELANCO CUSTOMERS ONLY: Save an average of 50% off list price on select vaccines.Available to new customers who have not purchased any Elanco products from any distributor in 2020.

12/31/2020

Rescue Disinfectant

Save $100 on four 1-gallon bottles (1 case) of Rescue AHP Liquid Disinfectant Concentrate. Plus, receive a Rescue starter kit from Virox for no additional charge.Limit one offer per customer. Available to the first 250 facilities. Starter kit will be sent by Virox within one week of qualifying purchase.

09/30/2020

Flexprofen Chewable Tablets for Dogs

Purchase $250 in any Vetoquinol products, get one 25mg case and one 100mg case of Flexprofen Chewable Tablets for Dogs at no charge (12 bottles each size).While supplies last. Offer only valid for Animal Welfare clinics that have an overseeing DVM on staff. Customer exclusions apply. Cannot be combined with any other Vetoquinol promo offer. Limit of 2 promotions per account.

10/31/2020

Medtronic suture and staplers

Save an average of 26% off list price on Medtronic suture and select staplers. Contact your Covetrus Territory Manager for a list of applicable products. 09/30/2020

SENERGY brand products

Purchase $1,000 or more in SENERGY brand products on a single invoice and receive a 30% rebate from Virbac at conclusion of promotion.Cannot be combined with any other Virbac offer. Eligible orders must be contained on one invoice. No limit to how many times a practice may participate during the offer period. Rebates will be issued in the form of a check at the end of the offer period.

10/31/2020

Select Virbac products

Buy 4, get 4 on Iverhart Max Chews, Veggie Dent Fr3sh, Rebound Recuperation, and Anxitane products (mix and match).No-charge items of equal or lesser value.

09/30/2020

855.724.3461 | northamerica.covetrus.com© 2020 Covetrus. All Rights Reserved. No copying without permission. Not responsible for typographical errors. 20SM255 (08/2020)

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Elanco’s Paws4PurposeTM 2020 Animal Welfare Level Agreement

Account Name:

Elanco Account Number:

Recommended Purchase Level

Business Phone #:

Business email:

2020 Animal Welfare Price List Product pricing effective December 15, 2019

PRODUCT NAME PACKAGING SKU# DISCOUNTPRICE

Canine Biologicals

Bronchi-Shield® III (intranasal canine adenovirus type 2, parainfluenza, Bordetella bronchiseptica) 25 x 1 dose AV688781AAM $72.41

Bronchi-Shield® ORAL(Bordetella bronchiseptica) 25 x 1 dose AV688581AAM $92.81

Duramune® Cv-K(coronavirus) 25 x 1 dose AV6803025AM $87.56

Duramune® Max 5(distemper, adenovirus type 2, parainfluenza, parvovirus) 25 x 1 dose AV679681AAM $71.05

Duramune® Max 5-CvK(distemper, adenovirus type 2, parainfluenza, parvovirus, coronavirus) 25 x 1 dose AV679881AAM $112.61

Duramune® Max 5-CvK/4L(distemper, adenovirus type 2, parainfluenza, parvovirus, coronavirus, L. grippotyphosa, L. pomona, L. canicola, L. icterohaemorrhagiae)

25 x 1 dose AV679981AAM $140.09

Duramune® Max 5/4L(distemper, adenovirus type 2, parainfluenza, parvovirus, L. grippotyphosa, L. pomona, L. canicola, L. icterohaemorrhagiae)

25 x 1 dose AV679781AAM $102.63

Duramune® Max PC(parvovirus, coronavirus) 25 x 1 dose AV680781AAM $111.84

Duramune® Max Pv(parvovirus) 25 x 1 dose AV6805025AM $72.37

LeptoVax® 4(L. grippotyphosa, L. pomona, L. canicola, L. icterohaemorrhagiae) 25 x 1 dose AV6880025AM $84.06

Duramune Lyme® + Max 5-CvK/4L(distemper, adenovirus type 2, parainfluenza, parvovirus, coronavirus, L. grippotyphosa, L. pomona, L. canicola, L. icterohaemorrhagiae + Borrelia burgdorferi)

25 x 1 dose AV681781AAM $353.66

Duramune Lyme® + LeptoVax® 4(L. grippotyphosa, L. pomona, L. canicola, L. icterohaemorrhagiae + Borrelia burgdorferi) 25 x 1 dose AV6812025AM $279.63

Duramune Lyme®

(Borrelia burgdorferi) 25 x 1 dose AV6810025AM $249.09

Duramune Lyme® + Max 5/4L(distemper, adenovirus type 2, parainfluenza, parvovirus, L. grippotyphosa, L. pomona, L. canicola, L. icterohaemorrhagiae + Borrelia burgdorferi)

25 x 1 dose AV681481AAM $319.29

ULTRA Duramune® DAP(distemper, adenovirus type 2, parvovirus) 25 x 1 dose AV682081AAM $130.93

ULTRA Duramune® DAP+C(distemper, adenovirus type 2, parvovirus, coronavirus) 25 x 1 dose AV682681AAM $215.86

ULTRA Duramune® DAP+4L(distemper, adenovirus type 2, parvovirus, L. canicola, L. grippotyphosa, L. icterohaemorrhagiae, L. pomona) 25 x 1 dose AV681881AAM $186.73

ULTRA Duramune® DAP+C/4L(distemper, adenovirus type 2, parvovirus, coronavirus, L. canicola, L. grippotyphosa, L. icterohaemorrhagiae, L. pomona)

25 x 1 dose AV682481AAM $262.35

ULTRA Duramune® 4L(L. canicola, L. grippotyphosa, L. icterohaemorrhagiae, L. pomona) 25 x 1 dose AV6822025AM $158.84

ULTRA Duramune® Lyme(Borrelia burgdorferi) 25 x 1 dose AV6828025AM $462.74

Customer Name Printed:

Customer Signature:

Date:

If you have questions please email Paws4Purpose.com or call 1-800-782-8977 option 2, option 2

The prices in this agreement are valid only for purchases of the above products when ordered from an Elanco Animal Health authorized distributor or directly from Elanco Animal Health. Elanco Animal Health reserves the right to evaluate accounts for adherence to purchasing level requirements, and for those not meeting volume commitments or other terms & conditions, revert to regular pricing. Participants are not eligible for any other special offers. Elanco Animal Health reserves the right to terminate or amend this agreement at any time. Elanco Animal Health reserves the right to change prices to this agreement.

Always read, understand and follow the label and use directions.

Bronchi-Shield, Deramaxx, Duramune, Duramune Lyme, Fel-O-Guard, Fel-O-Vax, Fel-O-Vax Lv-K, Rabvac, ULTRA, ULTRA Duramune, ULTRA Hybrid FVRCP, UltraNasal, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates.

© 2020 Elanco. PM-US-19-2115 S4

PRODUCT NAME PACKAGING SKU# DISCOUNTPRICE

Feline Biologicals

Fel-O-Guard® Plus 3(rhinotracheitis, calicivirus, panleukopenia) 25 x 1 dose AV686081AAM $57.61

Fel-O-Guard® Plus 3 + Lv-K(rhinotracheitis, calicivirus, panleukopenia, FeLV) 25 x 1 dose AV686281AAM $168.90

Fel-O-Guard® Plus 4(rhinotracheitis, calicivirus, panleukopenia, Chlamydia psittaci) 25 x 1 dose AV686481AAM $66.77

Fel-O-Guard® Plus 4 + Lv-K(rhinotracheitis, calicivirus, panleukopenia, Chlamydia psittaci + FeLV) 25 x 1 dose AV686681AAM $183.96

Fel-O-Vax® IV + CaliciVax®

(rhinotracheitis, calicivirus, panleukopenia, Chlamydia psittaci) 25 x 1 dose AV6836025AM $72.72

Fel-O-Vax Lv-K®

(FeLV) 25 x 1 dose AV6834025AM $160.64

Fel-O-Vax Lv-K® IV + CaliciVax®

(rhinotracheitis, calicivirus, panleukopenia, Chlamydia psittaci, FeLV) 25 x 1 dose AV6830025AM $183.78

Fel-O-Vax® PCT + CaliciVax®

(rhinotracheitis, calicivirus, panleukopenia) 25 x 1 dose AV6840025AM $67.43

Fel-O-Vax Lv-K® III + CaliciVax®

(rhinotracheitis, calicivirus, panleukopenia, FeLV) 25 x 1 dose AV6832025AM $168.57

ULTRA™ Fel-O-Vax® FeLV(FeLV) 25 x 1 dose AV6854025AM $314.42

ULTRA™ Fel-O-Vax® FVRCP(calicivirus (NOVEL), calicivirus (TRADITIONAL), panleukopenia, rhinotracheitis) 25 x 1 dose AV6852025AM $129.53

ULTRA™ Fel-O-Vax® Dual FCV(calicivirus (NOVEL), calicivirus (TRADITIONAL)) 25 x 1 dose AV6856025AM $121.78

ULTRA™ Fel-O-Vax® FVRCP+FeLV(calicivirus (NOVEL), calicivirus (TRADITIONAL), panleukopenia, rhinotracheitis, FeLV) 25 x 1 dose AV6850025AM $329.91

ULTRA Hybrid FVRCP®

(calicivirus (NOVEL), calicivirus (TRADITIONAL), panleukopenia, rhinotracheitis) 25 x 1 dose AV6858025AM $129.53

UltraNasal™ FVRCP (herpesvirus 1, calicivirus, panleukopenia (TRADITIONAL) 20 x 1 dose AV427580TAM $47.76

UltraNasal™ FVRC (herpesvirus 1, calicivirus (TRADITIONAL) 20 x 1 dose AV428580TAM $39.74

Canine and Feline Rabies Biologicals

Rabvac® 1(1-year rabies) 10 dose AV687410DAM $11.54

Rabvac® 1(1-year rabies) 50 x 1 dose AV687682GAM $57.67

Rabvac® 3(3-year rabies) 10 dose AV687010DAM $12.54

Rabvac® 3(3-year rabies) 50 x 1 dose AV687282GAM $61.30

OFFER VALID FOR PURCHASES DATED*August 1, 2020 — October 31, 2020*OR WHILE SUPPLIES LAST

DETA

ILS

TERMS AND CONDITIONS

The Shelter Program is intended for customers engaged in the rescue, adoption and shelter of dogs and cats. Customers must demonstrate non-profit status in order to qualify. Vetoquinol reserves the right to deny free goods to accounts if non-profit status is not demonstrated. Shelter orders placed on a personal DVM account will not be honored. Reselling of products to other shelters, veterinary organizations or directly to consumers (via internet, OTC or otherwise) is not allowed and will void this promotion. Customers participating in this promotion are not eligible for any other Vetoquinol promotions or rebates, including the 2020 Clinic Partnership Agrement. Purchase of a prescription product requires a valid veterinary license on file.

WHO QUALIFIES?Any organization that can exhibit nonprofit status; all 501(c)(3) organizations such as animal shelters, humane societies, zoos and wildlife refuges

1.800.267.5707vetoquinolusa.com

BUY $250WORTH OF VETOQUINOL PRODUCTS, GET

FREEFLEXPROFEN

ANIMALW

ELFAREPROMO

• For every $250 spent on Vetoquinol products, receive 12 bottles of 25mg and 12 bottles of 100mg of Flexprofen FREE

• $250 purchase may be a mix of any Vetoquinol product(s)

• Vetoquinol to ship all free goods

• Offer only valid for Animal Welfare clinics that have an overseeing DVM on staff

• Cannot be combined with any other Vetoquinol promo offer

• Limit of 2 promotions per account

• Account must be in good standing with Covetrus in order to participate in promotion

• To qualify for free goods, reference CVQ on invoice when ordering

To make a purchase,talk to your Virbac or distributorrepresentative, or call 1-844-484-7222.

Purchase a minimum of $1,000 in SENERGY Brand Products and receive a 30% rebate back on your total.

July 1, 2020 - October 31, 2020

PRODUCT PRODUCT # SIZE SUGGESTED

VET PRICEQUANTITY

PURCHASED

SENERGY™ (selamectin) for Kitten and Puppy Up to 5lbs 50090 10 Boxes of 3 Doses $246.24

SENERGY™ (selamectin) for Cats 5.1 to 15lbs 50095 10 Boxes of 3 Doses $283.68

SENERGY™ (selamectin) for Cats 15.1 to 22lbs 50097 10 Boxes of 3 Doses $290.88

SENERGY™ (selamectin) for Dogs 5 to 10lbs, Toy 50005 10 Boxes of 3 Doses $275.60

SENERGY™ (selamectin) for Dogs 10.1 to 20lbs, Small 50010 10 Boxes of 3 Doses $284.00

SENERGY™ (selamectin) for Dogs 20.1 to 40lbs, Medium 50020 10 Boxes of 3 Doses $298.25

SENERGY™ (selamectin) for Dogs 40.1 to 85lbs, Large 50040 10 Boxes of 3 Doses $298.60

SENERGY™ (selamectin) for Dogs 85.1 to 130lbs, X-Large 50085 10 Boxes of 3 Doses $390.60

© 2020 Virbac Corporation. All Rights Reserved. SENERGY is a trademark of Virbac S.A. 04/20

trusted pr tectionFrom a trusted partner

Important Safety Information: Do not use SENERGY™ (selamectin) in sick, debilitated or underweight animals. All dogs and cats should be tested for heartworm disease before starting a preventive protocol. Use only on cats that are at least 8 weeks old and dogs that are at least 6 weeks old. For people, SENERGY may be irritating to the skin and eyes. Wash hands after use. For complete prescribing information, contact Virbac Veterinary Support at 1-800-338-3659 or visit us.virbac.com.

* Cannot be combined with any other Virbac offer. Eligible orders must be contained on one invoice. There is no limit to how many times a practice may participate in this offer during the offer period. Rebates will be issued in the form of a check at the end of the offer period. Offer subject to change at any time.

SENERGY™ (selamectin)Topical Parasiticide For Dogs and Cats

CAUTION:US Federal law restricts this drug to use by or on the order of a licensed veterinarian.

DESCRIPTION:SENERGY (selamectin) Topical Parasiticide is available as a colorless to yellow, ready to use solution in single dose tubes for topical (dermal) treatment of dogs six weeks of age and older and cats eight weeks of age and older. The content of each tube is formulated to provide a minimum of 2.7 mg/lb (6 mg/kg) of body weight of selamectin. The chemical composition of selamectin is (5Z,25S)-25-cyclohexyl-4’-O-de(2,6-dideoxy-3-O-methyl-α-L- arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22, 23-dihydro-5-hydroxyiminoavermectin A1a.

INDICATIONS:SENERGY is recommended for use in dogs six weeks of age or older and cats eight weeks of age and older for the following parasites and indications:

Dogs:SENERGY kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the prevention and control of flea infestations (Ctenocephalides felis), prevention of heartworm disease caused by Dirofilaria immitis, and the treatment and control of ear mite (Otodectes cynotis) infestations. SENERGY also is indicated for the treatment and control of sarcoptic mange (Sarcoptes scabiei) and for the control of tick infestations due to Dermacentor variabilis.

Cats:SENERGY kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the prevention and control of flea infestations (Ctenocephalides felis), prevention of heartworm disease caused by Dirofilaria immitis, and the treatment and control of ear mite (Otodectes cynotis) infestations. SENERGY is also indicated for the treatment and control of roundworm (Toxocara cati) and intestinal hookworm (Ancylostoma tubaeforme) infections in cats.

WARNINGS:Not for human use. Keep out of the reach of children. In humans, SENERGY may be irritating to skin and eyes. Reactions such as hives, itching and skin redness have been reported in humans in rare instances. Individuals with known hypersensitivity to SENERGY should use the product with caution or consult a health care professional. SENERGY contains isopropyl alcohol and the preservative butylated hydroxytoluene (BHT). Wash hands after use and wash off any product in contact with the skin immediately with soap and water. If contact with eyes occurs, then flush eyes copiously with water. In case of ingestion by a human, contact a physician immediately. The safety data sheet (SDS) provides more detailed occupational safety information. To report suspected adverse drug events, for technical assistance or to obtain a copy of the SDS, contact Virbac AH, Inc. at 1-800-338-3659 or us.virbac.com.For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or http://www.fda.gov/reportanimalae.Flammable - Keep away from heat, sparks, open flames or other sources of ignition.Do not use in sick, debilitated or underweight animals (see SAFETY).

PRECAUTIONS:Prior to administration of SENERGY, dogs should be tested for existing heartworm infections. At the discretion of the veterinarian, infected dogs should be treated to remove adult heartworms. Selamectin is not effective against adult D. immitis and, while the number of circulating microfilariae may decrease following treatment, selamectin is not effective for microfilariae clearance.Hypersensitivity reactions have not been observed in dogs with patent heartworm infections administered three times the recommended dose of selamectin. Higher doses were not tested.

ADVERSE REACTIONS: Pre-approval clinical trials:Following treatment with selamectin, transient localized alopecia with or without inflammation at or near the site of application was observed in approximately 1% of 691 treated cats. Other signs observed rarely (≤0.5% of 1743 treated cats and dogs) included vomiting, loose stool or diarrhea with or without blood, anorexia, lethargy, salivation, tachypnea, and muscle tremors.

Post-approval experience:In addition to the aforementioned clinical signs that were reported in pre-approval clinical trials, there have been reports of pruritus, urticaria, erythema, ataxia, fever, and rare reports of death. There have also been rare reports of seizures in dogs (see WARNINGS).

DOSAGE:The recommended minimum dose is 2.7 mg selamectin per pound (6 mg/kg) of body weight.Administer the entire contents of a single dose tube (or two tubes used in combination for dogs weighing over 130 pounds) of SENERGY topically in accordance with the following tables. (See ADMINISTRATION for the recommended treatment intervals.)

Cats (lb) Package Color

mg per tube

Potency (mg/mL)

Administered volume (mL)

Up to 5 Mauve 15 mg 60 0.255.1–15 Blue 45 mg 60 0.75

15.1–22 Taupe 60 mg 60 1.0

For cats over 22 lbs use the appropriate combination of tubes.

Dogs (lb) Package Color

mg per tube

Potency (mg/mL)

Administered volume (mL)

Up to 5 Mauve 15 mg 60 0.255.1–10 Lavender 30mg 120 0.2510.1–20 Brown 60 mg 120 0.520.1–40 Red 120 mg 120 1.040.1–85 Teal 240 mg 120 2.0

85.1–130 Plum 360 mg 120 3.0

For dogs over 130 lbs use the appropriate combination of tubes. Recommended for use in dogs 6 weeks of age and older and in cats 8 weeks of age and older.

ADMINISTRATION:A veterinarian or veterinary technician should demonstrate or instruct the pet owner regarding the appropriate technique for applying SENERGY topically to dogs and cats prior to first use. Remove the tube from the package and hold upright with the lot and expiration at the bottom. Bend the tip back until it snaps off. To administer the product, part the hair on the back of the animal at the base of the neck in front of the shoulder blades until the skin is visible. Place the tip of the tube on the skin and squeeze the tube 3 or 4 times to empty its entire contents directly onto the skin in one spot. Keeping the tube squeezed, drag it away from the liquid and lift to remove. Check the tube to ensure that it is empty. Do not massage the product into the skin. Due to alcohol content, do not apply to broken skin. Avoid contact between the product and fingers. Do not apply when the haircoat is wet. Bathing or shampooing the dog 2 or more hours after treatment will not reduce the effectiveness of SENERGY against fleas or heartworm. Bathing or shampooing the cat 2 hours after treatment will not reduce the effectiveness of SENERGY against fleas. Bathing or shampooing the cat 24 hours after treatment will not reduce the effectiveness of SENERGY against heartworm. Stiff hair, clumping of hair, hair discoloration, or a slight powdery residue may be observed at the treatment site in some animals. These effects are temporary and do not affect the safety or effectiveness of the product. Discard empty tubes in your ordinary household refuse.

Flea Control in Dogs and CatsFor the prevention and control of flea infestations, SENERGY should be administered at monthly intervals throughout the flea season, starting one month before fleas become active. In controlled laboratory studies >98% of fleas were killed within 36 hours. Results of clinical field studies using selamectin monthly demonstrated >90% control of flea infestations within 30 days of the first dose. Dogs and cats treated with selamectin, including those with pre-existing flea allergy dermatitis, showed improvement in clinical signs associated with fleas as a direct result of eliminating the fleas from the animals and their environment.If the dog or cat is already infested with fleas when the first dose of selamectin is administered, adult fleas on the animal are killed and no viable fleas hatch from eggs after the first administration. However, an environmental infestation of fleas may persist for a short time after beginning treatment with selamectin because of the emergence of adult fleas from pupae.

Heartworm Prevention in Dogs and CatsFor the prevention of heartworm disease, SENERGY must be administered on a monthly basis. SENERGY may be administered year-round or at least within one month after the animal’s first exposure to mosquitoes and monthly thereafter until the end of the mosquito season. The final dose must be given within one month after the last exposure to mosquitoes. If a dose is missed and a monthly interval between dosing is exceeded then immediate administration of SENERGY and resumption of monthly dosing will minimize the opportunity for the development of adult heartworms. When replacing another heartworm preventive product in a heartworm disease prevention program, the first dose of SENERGY must be given within a month of the last dose of the former medication.Selamectin, the active ingredient in SENERGY, is a macrocyclic lactone compound. These compounds effectively prevent the development of adult heartworms when administered to dogs and cats within one month of exposure to infective (L3) Dirofilaria immitis larvae. Efficacy of macrocyclic lactones decreases below 100% in dogs, however, if first administered >2 months after exposure to infective larvae. Thus, in heartworm endemic regions, delaying initiation of heartworm prevention using SENERGY beyond 2 months of first exposure to infective larvae (e.g., starting puppies and kittens at >8 weeks of age), or gaps of >2 months in the administration of SENERGY during periods of heartworm transmission, increases the risk of the animal acquiring heartworms. Animals with unknown heartworm history that test negative for heartworms prior to the initiation of SENERGY may beharboring pre-patent infections at the time SENERGY was started. Testing such animals 3–4 months after initiation of SENERGY would be necessary to confirm their negative heartworm status.At the discretion of the veterinarian, cats ≥6 months of age may be tested to determine the presence of existing heartworm infections before beginning treatment with SENERGY. Cats already infected with adult heartworms can be given SENERGY monthly to prevent further infections.

Ear Mite Treatment in Dogs and CatsFor the treatment of ear mite (O. cynotis) infestations in dogs and cats, SENERGY should be administered once as a single topical dose. A second monthly dose may be required in some dogs. Monthly use of SENERGY will control any subsequent ear mite infestations. In the clinical field trials ears were not cleaned, and many animals still had debris in their ears after the second dose. Cleansing of the infested ears is recommended to remove the debris.

Sarcoptic Mange Treatment in DogsFor the treatment of sarcoptic mange (S. scabiei) in dogs, SENERGY should be administered once as a single topical dose. A second monthly dose may be required in some dogs. Monthly use of SENERGY will control any subsequent sarcoptic mange mite infestations. Because of the difficulty in finding sarcoptic mange mites on skin scrapings, effectiveness assessments also were based on resolution of clinical signs. Resolution of the pruritus associated with the mite infestations was observed in approximately 50% of the dogs 30 days after the first treatment and in approximately 90% of the dogs 30 days after the second monthly treatment.

Tick Control in DogsFor the control of tick (Dermacentor variabilis) infestations in dogs, SENERGY should be administered on a monthly basis. In heavy tick infestations, complete efficacy may not be achieved after the first dose. In these cases, one additional dose may be administered two weeks after the previous dose, with monthly dosing continued thereafter.

Nematode Treatment in CatsFor the treatment and control of intestinal hookworm (A. tubaeforme) and roundworm (T. cati) infections, SENERGY should be applied once as a single topical dose.

SAFETY:Selamectin has been tested safe in over 100 different pure and mixed breeds of healthy dogs and over 15 different pure and mixed breeds of healthy cats, including pregnant and lactating females, breeding males and females, puppies six weeks of age and older, kittens eight weeks of age and older, and avermectin-sensitive collies. A kitten, estimated to be 5–6 weeks old (0.3 kg), died 8 1/2 hours after receiving a single treatment of selamectin at the recommended dosage. The kitten displayed clinical signs which included muscle spasms, salivation and neurological signs. The kitten was a stray with an unknown history and was malnourished and underweight (see WARNINGS). DOGS: In safety studies, selamectin was administered at 1, 3, 5, and 10 times the recommended dose to six-week-old puppies, and no adverse reactions were observed. The safety of selamectin administered orally also was tested in case of accidental oral ingestion. Oral administration of selamectin at the recommended topical dose in 5- to 8-month-old beagles did not cause any adverse reactions. In a pre-clinical study selamectin was dosed orally to ivermectin-sensitive collies. Oral administration of 2.5, 10, and 15 mg/kg in this dose escalating study did not cause any adverse reactions; however, eight hours after receiving 5 mg/kg orally, one avermectin-sensitive collie became ataxic for several hours, but did not show any other adverse reactions after receiving subsequent doses of 10 and 15 mg/kg orally. In a topical safety study conducted with avermectin-sensitive collies at 1, 3 and 5 times the recommended dose of selamectin, salivation was observed in all treatment groups, including the vehicle control. Selamectin also was administered at 3 times the recommended dose to heartworm infected dogs, and no adverse effects were observed. CATS: In safety studies, selamectin was applied at 1, 3, 5, and 10 times the recommended dose to six-week-old kittens. No adverse reactions were observed. The safety of selamectin administered orally also was tested in case of accidental oral ingestion. Oral administration of the recommended topical dose of selamectin to cats caused salivation and intermittent vomiting. Selamectin also was applied at 4 times the recommended dose to patent heartworm infected cats, and no adverse reactions were observed.In well-controlled clinical studies, selamectin was used safely in animals receiving other frequently used veterinary products such as vaccines, anthelmintics, antiparasitics, antibiotics, steroids, collars, shampoos and dips.

STORAGE CONDITIONS: Store below 25°C (77°F).

HOW SUPPLIED: Available in eight separate dose strengths for dogs and cats of different weights (see DOSAGE). SENERGY for puppies and kittens is available in cartons containing 3 single dose tubes. SENERGY for cats and dogs is available in cartons containing 3 single dose tubes.

Distributed by: Virbac AH, Inc. P.O. Box 162059 Fort Worth, TX 76161Approved by FDA under ANADA # 200-670 ©2020 Virbac Corporation. All Rights Reserved. SENERGY™

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