lectures on respiratory physiology mechanics of breathing i

26
Lectures on respiratory Lectures on respiratory physiology physiology Mechanics of Breathing Mechanics of Breathing I I

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Page 1: Lectures on respiratory physiology Mechanics of Breathing I

Lectures on respiratory physiologyLectures on respiratory physiology

Mechanics of Breathing IMechanics of Breathing I

Page 2: Lectures on respiratory physiology Mechanics of Breathing I

Perfect Lung

Action of the diaphragm

Page 3: Lectures on respiratory physiology Mechanics of Breathing I

Perfect Lung

Action of the intercostal muscles

Page 4: Lectures on respiratory physiology Mechanics of Breathing I

Perfect Lung

Action of the abdominal muscles

Page 5: Lectures on respiratory physiology Mechanics of Breathing I

Perfect Lung

Action of the intercostal muscles

Page 6: Lectures on respiratory physiology Mechanics of Breathing I

Perfect Lung

Pressure-volume curve of the lung

Page 7: Lectures on respiratory physiology Mechanics of Breathing I

3000

2000

1000

FRC

0 -10 -20 -30

Intrapleural pressure (cmH2O)

Vo

lum

e a

bo

ve

FR

C (

ml)

COMPLIANCE = ΔV / ΔP

=1000/5

= 200 ml/cmH2OΔV

ΔP

Compliance of lung

Page 8: Lectures on respiratory physiology Mechanics of Breathing I

Perfect Lung

Capillary showing collagen (Col)

Page 9: Lectures on respiratory physiology Mechanics of Breathing I

Perfect Lung

Fibers of elastin

Page 10: Lectures on respiratory physiology Mechanics of Breathing I

Perfect Lung

Some effects of surface tension

Page 11: Lectures on respiratory physiology Mechanics of Breathing I

Perfect Lung

Comparison of air and saline inflation

Page 12: Lectures on respiratory physiology Mechanics of Breathing I

Perfect Lung

Measurement of surface tension and its behavior

Page 13: Lectures on respiratory physiology Mechanics of Breathing I

Perfect Lung

Comparison of air and saline inflation

Page 14: Lectures on respiratory physiology Mechanics of Breathing I

Type II alveolar epithelial cell

Page 15: Lectures on respiratory physiology Mechanics of Breathing I

Type II cell showing lamellar inclusion bodies (LIB)

Page 16: Lectures on respiratory physiology Mechanics of Breathing I

Lung with absence of surfactant

Page 17: Lectures on respiratory physiology Mechanics of Breathing I

Regional differences of ventilation at FRC

Page 18: Lectures on respiratory physiology Mechanics of Breathing I

Regional differences of ventilation at RV

Page 19: Lectures on respiratory physiology Mechanics of Breathing I

Alveoli are larger at the apex (upper panel) than base (lower)

Page 20: Lectures on respiratory physiology Mechanics of Breathing I

Airway closure at the lung base

Page 21: Lectures on respiratory physiology Mechanics of Breathing I

Pressure changes with bilateral pneumothorax

Page 22: Lectures on respiratory physiology Mechanics of Breathing I

Pneumothorax of right lung

Page 23: Lectures on respiratory physiology Mechanics of Breathing I

Fibrosis of right lung

Page 24: Lectures on respiratory physiology Mechanics of Breathing I

Relaxation pressure-volume curves

Page 25: Lectures on respiratory physiology Mechanics of Breathing I

Perfect Lung

Pressure-volume curve of the lung

Page 26: Lectures on respiratory physiology Mechanics of Breathing I

Relaxation pressure-volume curves