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    Ectopic Eruption

    Exfoliation (Contd.) Exfoliation is symmetrical on either side of

    arches Girls tend to shed teeth earlier than Boys Resorption process has period of rest & period

    of repair- explain for intermittent mobility ofprimary teeth

    Premature exfoliation leads to either earlyeruption / delayed eruption

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    Premature exfoliation : Primary teeth(Causes)

    Toxicities (Acrodynia & Radiation) Metabolic disorders (Acatalasia, Chediak-Higashi

    disease, Hypophosphatasia) Malignancies (Langerhans cell histiocytosis, leukemia,

    cyclic neutropenia, agranulocytosis) Dental causes (Caries related infections, trauma,

    periodontitis, Papillon Lefevre syndrome, Cherubism) Miscellaneous causes (Tumors of jaw, self mutilation,,

    extreme bruxism)

    Acrodynia Also known as Pink Disease Chronic exposure to mercury, ointments or medications Amalgam restorations do not cause Acrodynia Primarily affects young children Often occurs in infants, age of onset being between 4

    months and 8 years Symptoms : Fever, irritability, photophobia, pinkdiscoloration of hands & feet, polyneuritis & painfulextremities

    Orally : Excessive salivation, swelling, loss of alveolarbone, focal gum erosion with subsequent loss of teeth

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    Chediak-Higashi disease

    Abnormal platelets causes spont. bleeding & easy bruising 85% of children with CHD develop unusual lymphoma-like

    condition generally leading to death Remaining 15% presents less severe clinical manifestations The oral lesions are consequence of repeated infections Consist of ulcers, markedly hypertrophic gingivitis and

    severe periodontal destruction Due to recurrent intraoral infections, extensive alveolar

    bone loss occurs which in most patients leads to toothexfoliation

    Hypophosphatasia

    Characterized by diminished serum levels of alkalinephosphatase and phosphoethanolamine in urine

    4 groups: perinatal (lethal), infantile, childhood & adult Phenotype range from premature loss of decidious teeth

    to severe bone abnormality leading to neonatal death. Abnormal cementum or lack of cementum may lead to

    spontaneous shedding of primary teeth, affectingincisors more than molars

    Pulp chambers unusually large Dentinal dysplasia is seen Higher incidence of uni-radicular primary teeth is shed

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    Histiocytosis

    3 variants :Lettere-Siwe disease (most severe form)Hand schuller Christian disease (affects children above 3

    yrs & involves mostly bones)Eosinophilic granuloma (affects older children & is benign

    in nature) Neoplastic proliferation of Langerhans' histiocytes C.M: Scaly erythematous skin rashes : scalp &

    extremities, fever, anemia, hepatosplenomegaly O.M: Swelling, ulceration, gingival necrosis, radiolucent

    lesion of mandible & skull. Management: Chemotherapy, radiotherapy, surgical

    curettage

    Leukemia

    Immature neoplastic white blood cells in circulation Hyperplastic gingivitis with cyanotic bluish-red discolor. Oral tissues are friable and bleed easily Hyperplastic gingivae may completely cover the teeth In severe cases, purpuric lesions and necrotic ulcers Alveolar bone destruction & necrosis of PDL may

    occasionally lead to loosening & exfoliation of teeth Treatment : systemic & palliative - chemotherapy,

    radiation, bone marrow transplant Oral cavity - free of local irritants Child instructed to maintain a high level of oral hygiene

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    Cyclic neutropenia Can occur at any age Rythemic reduction in PMN in 21 day cycle Risk for opportunistic infection (affected during the

    interval of neutropenia, in a 21 day cycle, concomitantwith oscillation of bone marrow blood cell production)

    Fever, malaise, sore throat, stomatitis, regionallymphadenopathy, headache, cutaneous infection,conjunctivitis

    Gingivitis, ulceration, loosening of teeth, loss of

    supporting bone Repeated insult as gingiva return to normal during the

    cycle, when neutrophil count is normal

    Cyclic neutropenia

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    Papillon Lefevre syndrome

    Marked destruction of periodontium (periodontoclasia) Unknown cause Depressed peripheral blood neutrophil chemotaxis. Palmar and plantar hyperkeratosis Horizontal bone loss, infected periodontal pockets Loosening of primary teeth leading to premature loss Possible organism: Actinobacillus actinomycetemcomitans,

    Fusebacterium nucleatum Management : Specific antibiotic therapy, extraction,

    denture fabrication

    Papillon Lefevre syndrome

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    Cherubism

    Fibro-osseous lesion of jaws involving more than onequadrant

    Stabilizes after growth period Usually leaving some facial deformity and malocclusion Ground glass appearance RG : Unilocular/multilocular bilateral expansive

    radiolucenices Faint radiopacities resembling residual bones sometime

    present at puberty

    Self mutilation Purposeful traumatizing ones own oral structures Local cause, Emotional cause Finger Nails, Bobby pins, Pacifier Lower anterior teeth , Cheeks, lower lip Necrosis of tissue, loosening of teethLesch-Nyhan Syndrome : Spastic cerebral palsy, mental retardation, severe

    motor disability, cognition, ocular motility andbehavioral control

    Self mutilating aggressive behavior - mutilation of lipsby constant chewing on them

    Teeth are lost due to prophylactic extractions

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    Lesch-Nyhan Syndrome

    Odontodysplasia

    Also k/n as Ghost teeth Affected teeth are poorly mineralized Lack of proper calcification of E, D & C Abnormal pulp chamber & root shape

    Radiographically appear abnormal in size & shape Permanent teeth affected more frequently then primaryteeth

    Generally fail to erupt but if they do; have consistency ofgelatin

    Often need to be extracted

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    Diagnosis of early exfoliation(Contd /-)

    Medical History Family history of loss of teeth, systemic disease History of skin infections/lesions, otitis media, or

    other recurrent infection Hyperkeratosis of palms or soles of feet Exophthalmia Pale mucosa or petechiae Neurologic disorders

    Implications of early exfoliation of primary teeth : Change may be necessary, for example : caries, diet,

    hygiene Precautions may be necessary : radiation, salivary

    stimulant or substitute If part of a syndrome, need to determine what other

    issues ariseConcerns : Esthetics Speech Eating, nutrition, diet Self-esteem, psyche Health of succedaneous teeth