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Lecture 3: Viruses

Dr. Dimos

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Virology

Not a virus

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Structure of Viruses

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Components of Viruses

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Medically Relevant DNA RNA Viruses

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Multiplication Cycles in AnimalViruses

!"e general p"ases in t"e life cycle ofanimal viruses are adsorption # penetration # uncoating #

synthesis # assembly # and release from t"e "ost cell.

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$eneral features in t"e multiplicationcycle of RNA animal viruses

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$eneral features in t"e multiplicationcycle of DNA viruses.

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Viruses !"at%nfect &acteria

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!'o principal means (y '"ic"animal viruses penetrate.

(a) )ndocytosis *engulfment+ and uncoating of a "erpesvirus. (b) ,usionof t"e cell mem(rane 'it" t"e viral envelope *mumps virus+.

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!"ree mec"anisms for viralinduction of cancer.

Papillomavirus *genital 'arts are associated 'it"

cervical cancer+ Herpesviruses *)pstein &arr virus causes &ur/itt0s

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Viral Replication and Diseases: 1%V

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Viral Replication and Diseases:Ra(ies

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Viral Replication and Diseases:1epatitis

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Anti(odies

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Vaccines: %nactivated vs. Attenuated

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Relen2a: Neuraminidase %n"i(itor

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Acyclovir