Lecture 18

Mass Spectroscopy I

Harris Ch.22

1420146.0

208_

2/1

m

mpowerresolving

Ion Source Mass Selector Detector

Data Processing

Mass Spectrometer

Ion Detectors

V

+++

Energy gain: E = zV Kinetic energy2

2

mv

z

mconst

zV

mlength

v

lengthtime

m

zVv

m

zVvzV

mv

2

2

2or ,

22

2

Time-of-Flight

Quadrupole

Ion Cyclotron Resonance

(FT Mass Spectrometry)

Ion Source Mass Selector Detector

Data Processing

Mass Spectrometer

C

CC

C

CC H

H

H

H

H

H

+

+

HH

C

CC

C

CC

H

H

H

H

H

C CH

CC

C C

H

HH

H

H

C

CC

C

H

H

H

+

C C HH

Electron ionization of benzene molecule

Electrospray

CO OH

OH

OH

CO OH

NH2

MALDIMatrix Assisted Laser Desorption/Ionization