leading the quest for health reproductive health disparities” a lifespan approach kimberly d....
TRANSCRIPT
![Page 1: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/1.jpg)
Leading The Quest For Health
Reproductive Health Disparities”A Lifespan ApproachKimberly D. Gregory MD, MPHAssociate ProfessorCedars Sinai Medical CenterDavid Geffen School of Medicine &UCLA School of Public Health
![Page 2: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/2.jpg)
KD Gregory 4/06
Reproductive Health Disparities
Why should we care? What is the magnitude of the problem?
Over 90% of US women expect to give birth at least once during their lifetime
4.1 million births in US 60% or more additional pregnancies=tabs, sabs, SB Approximately 6.4 million pregnancy related events Significant issue with regard to health care costs,
health care resources, personal joy/suffering
![Page 3: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/3.jpg)
KD Gregory 4/06
Reproductive Health Disparities
Pregnancy is a significant event in a woman’s life and has a profound impact on her health and well-being
Emerging data that the health and well-being of a woman sets the stage for the health and well-being of her offspring, and ultimately her family
![Page 4: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/4.jpg)
KD Gregory 4/06
Reproductive Health Disparities
Policy implications Representative indicators specific to women’s health
are widely used to reflect the health of a population (e.g. MMR, IMR)
US has low MMR 11.5/100,000 vs relatively high IMR 6.9/1000 live births—Ranks 25th internationally
Hence, measuring, monitoring and reporting indicators of women’s health should be a national priority
![Page 5: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/5.jpg)
KD Gregory 4/06
Reproductive Health Disparities
Women’s Health = Pregnancy Traditional indicators Fertility MMR Onset, adequacy of prenatal
care Fetal and infant mortality Prematurity Low Birth Weight
![Page 6: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/6.jpg)
KD Gregory 4/06
Reproductive Health Disparities
Women’s Health = Pregnancy Review recognized disparities in pregnancy and women’s health related to women’s reproductive health conditions
Frame the discussion within the context of a women’s reproductive life span
Provides an opportunity to identify the gaps in knowledge about women’s health outcomes, and to begin to conceptualize potential solutions
Will not address chronic medical conditions
![Page 7: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/7.jpg)
KD Gregory 4/06
The Women’s Health Continuum: A Lifespan Approach
Health Maintenance
Post Reproductive
Years
Pre-pregnancyPlanning Pregnancy Postpartum
Newborn (a new life*)
*Fetal origins of adult diseases
PubertyPreconceptionPregnancyPostpartumNewbornInterconceptionMenopausePostreproduction
![Page 8: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/8.jpg)
KD Gregory 4/06
The Women’s Health Continuum: A Lifespan Approach
Health Maintenance
Post Reproductive
Years
Pre-pregnancyPlanning Pregnancy Postpartum
Newborn (a new life*)
*Fetal origins of adult diseases
Conditions are not exhaustive or mutually exclusive to anytime periodNo attempt to address chronic diseases
![Page 9: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/9.jpg)
KD Gregory 4/06
Puberty
Condition Total White Black Hispanic Asian Other
Puberty (X age, years)
12.7 12.0 --- >white >white
•Trend toward earlier maturation in AA girls as compared with Caucasian girls•AA girls enter puberty 1 to 1.5 yrs earlier (age 8 to 9 years) and start menses 8.5 months earlier (12.1 yrs)•Asians, American Indians comparable (or later) than Caucasian•MA enter puberty at the same time as Caucasian girls, but delayed maturation: reach adult stages later
![Page 10: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/10.jpg)
KD Gregory 4/06
Puberty
Condition Total White Black Hispanic Asian Other
Puberty (X age, years)
12.7 12.0 --- >white >white
•Are these “Differences” or “Disparities”?•Environmental factors (lead, nutrition, obesity) influence maturation, and these risk factors are disproportionatelydistributed•Important clinical, educational, and social implications
•Referrals for precocious or delayed puberty•Anticipatory guidance “what to expect when”•Determining time and age appropriate sex education
![Page 11: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/11.jpg)
KD Gregory 4/06
Puberty & Preconception
Condition Total White Black Hispanic Asian Other
Puberty (X age, years)
12.7 12.0 --- >white >white
Current Contraception use
46.6 66.6 62.2 58.9 --- ---
STD/PID 8.0 8.0 11.0 --- ---
Teen pregnancy
45.9 28.5 68.3 83.4 18.3 53.8 NA
Abortion 25.6 17.1 52.9 26.1 --- ---
![Page 12: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/12.jpg)
KD Gregory 4/06
Preconception
Maternal health during pregnancy is directly related to maternal health prior to pregnancy
Emerging emphasis on preconception care and health maintenance
Women seen by providers during this time should be considered “at risk” for conception
Each visit viewed as contraception or preconception visits— Provide health promotion or primary preventive services— Condoms decrease STD’s (and pregnancy)— Contraception decrease unintended pregnancies (50% of
pregnancies); delay first births, promote birth spacing by at least 2 years
![Page 13: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/13.jpg)
KD Gregory 4/06
Preconception
CDC individual level actions by health practitioners to reduce maternal and infant mortality and promote the health of all childbearing-aged women at preconception/interconception visits— Screening for preexisting chronic conditions and health
risks— Counseling about contraception and access to effective
family planning to prevent unintended pregnancy & unnecessary abortion
— Counseling about good nutrition including iron, folic acid— Advise re: regular exercise, ETOH, smoking, drugs
![Page 14: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/14.jpg)
KD Gregory 4/06
The Women’s Health Continuum: A Lifespan Approach
Health Maintenance
Post Reproductive
Years
Pre-pregnancyPlanning Pregnancy Postpartum
Newborn (a new life*)
*Fetal origins of adult diseases
![Page 15: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/15.jpg)
KD Gregory 4/06
Pregnancy
90% of US women expect to give birth at least once during their lifetime
Good opportunity for health promotion and primary preventive services— May be the only period where some women have coverage— Most women are motivated to change behaviors to optimize
pregnancy outcome— Studies suggest women who seek prenatal care sustain
interactions with the health care system for their newborn (e.g. well baby checks, immunizations, etc)
![Page 16: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/16.jpg)
KD Gregory 4/06
Pregnancy
Condition Total White Black Hispanic Asian Other
Prenatal care, 1st trimester
83.2 85.0 74.3 74.4
75.6 MA79.1 PR
91.8 CU
77.4 CA
84.0
90.1 JA
87.0 CH
85.0 FIL
82.7 OT79.1 HA
69.3 NA
No PNC 3.7 3.2 6.5 5.9 8.2 6.5
![Page 17: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/17.jpg)
KD Gregory 4/06
Pregnancy
Condition Total White Black Hispanic Asian Other
Fertility rate (/1000 reproductive age woman)
67.5 58.0 69.3 107.4 69.4 70.4
Birth rate (/1000 population)
3.7 3.2 6.5 5.9 8.2 6.5
•All ethnic groups have higher fertility and birth rates than Caucasians•Changing population demographics makes understanding differences important with regard to prevention/intervention strategies and health care costs and resource utilization
![Page 18: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/18.jpg)
KD Gregory 4/06
Pregnancy
Condition Total White Black Hispanic Asian Other
Miscarriages (% clinically recognized)
13.8 13.8 13.5 --- --- --
Ectopics 1.3 1.2 1.6 --- --- ---
![Page 19: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/19.jpg)
KD Gregory 4/06
Pregnancy
Condition Total White Black Hispanic Asian Other
Maternal mortality
11.5 6.0 25.1 10.3 11.3 12.2 NA
Pregnancy comps
GD 2.9
HTN 3.9
2.7
4.2
2.8
2.8
2.9
3.9
--- ---
Cesarean rate
26.1 25.9 27.6 25.2*
36.9 CU
25.0 23.1
Age >35 48.3 48.5 39.4 60.3 73.1 39.8
![Page 20: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/20.jpg)
KD Gregory 4/06
Pregnancy
Condition Total White Black Hispanic Asian Other
Infertility 15.0 --- --- --- --- ---
Primary Etiology
Ovarian 46.5 14.5
Male fx 24.5 11.5
Other 15.3 3.6
Tubal 13.8 41.0
Unknown 11.0 12.8
Endometrial
4.7 2.6
Sterilized 4.6 25.6
![Page 21: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/21.jpg)
KD Gregory 4/06
The Women’s Health Continuum: A Lifespan Approach
Health Maintenance
Post Reproductive
Years
Pre-pregnancyPlanning Pregnancy Postpartum
Newborn (a new life*)
*Fetal origins of adult diseases
![Page 22: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/22.jpg)
KD Gregory 4/06
Newborn
Condition Total White Black Hispanic Asian Other
Perinatal mortality
--- 1.9 4.7 1.9 --- ---
Fetal deaths
6.6 5.6 12.4 --- --- ---
Neonatal Mortality
4.6 3.8 9.4 3.7 --- ---
Infant Mortality
6.9 5.7 14.1 5.6 5.1 9.0 NA
![Page 23: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/23.jpg)
KD Gregory 4/06
Newborn
Condition Total White Black Hispanic Asian Other
Infant Mortality
6.9 5.7 14.1 5.6 5.1 9.0 NA
5.5 MA8.1 PR4.3 CU
4.9 CA
3.8 JA3.5 CH
5.9 FIL
5.2 OTH8.7 HA
Diversity among subtypes with Puerto Ricans and Hawaiians having intermediate ratesCompared to AA and Caucasians. Cubans, Japanese, and Chinese = Caucasians
![Page 24: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/24.jpg)
KD Gregory 4/06
Newborn
Condition Total White Black Hispanic Asian Other
Preterm birth
12.1 11.1 17.5 11.6* 10.4* 13.1 NA
Low Birth Weight
7.8 6.8 13.3 7.8* 7.8* 7.2
VLBW
<1500 g1.5 1.2 3.1 1.5* 1.1* 1.3
IUGR at term
2.9 2.5 5.2 4.0 --- ---
* Variation in rates by different population subtypes
![Page 25: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/25.jpg)
KD Gregory 4/06
The Women’s Health Continuum: A Lifespan Approach
Health Maintenance
Post Reproductive
Years
Pre-pregnancyPlanning Pregnancy Postpartum
Newborn (a new life*)
*Fetal origins of adult diseases
![Page 26: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/26.jpg)
KD Gregory 4/06
Postpartum & Interconception Health Maintenance
Opportunity for further prevention, screening and interventions Postpartum visit-increased emphasis by ACOG & NCQA Prevention, detection, and early treatment of complications
(e.g. hemorrhage, eclampsia, infection and postpartum depression)
Information and education (child care, breast feeding, nutrition, and contraception
WHO Technical Working Group Postpartum Care suggest one visit isn’t enough and advocates for 6 hours, 6 days, 6 weeks, and 6 mos as critical time when provider visits might be valuable in identifying maternal or neonatal health needs or complications
![Page 27: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/27.jpg)
KD Gregory 4/06
Postpartum & Interconception Health Maintenance
Condition Total White Black Hispanic Asian Other
Breast-feeding
55.2 59.1 25.1 62.2 --- ---
Depression 8.0
Fibroids (/1000 women)
9.2 8.2 16.9 --- --- ---
Chronic GYN (/1000 women)
97.1
![Page 28: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/28.jpg)
KD Gregory 4/06
Interconception Health Maintenance
Gynecologic disorders—Menstrual disorders (most common)—Adnexal conditions (cysts)—Fibroids (20% of women; age, AA)—Endometriosis—Chronic pelvic pain
![Page 29: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/29.jpg)
KD Gregory 4/06
The Women’s Health Continuum: A Lifespan Approach
Health Maintenance
Post Reproductive
Years
Pre-pregnancyPlanning Pregnancy Postpartum
Newborn (a new life*)
*Fetal origins of adult diseases
![Page 30: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/30.jpg)
KD Gregory 4/06
Post Reproduction and Menopause
Study of Women’s Health Across the Nation (SWAN) —Median age 51.4 (adjusted for smoking education,
marital status, heart disease, parity, race and ethnicity, employment, prior OC’s)
—Current smoking, lower SES associated with earlier menopause
—Parity, prior OC use and Japanese race/ethnicity associated with later menopause
![Page 31: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/31.jpg)
KD Gregory 4/06
Post Reproduction and Menopause
Significant racial, ethnic, and sociocultural differences in how menopause is experienced and perceived
Japanese and Chinese women reported fewest symptoms
Hispanic women reported the most AA more likely to report hot flashes and vaginal
dryness White women more likely to report urine leakage and
difficulty sleeping Symptoms mediated by BMI, smoking and SES
![Page 32: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/32.jpg)
KD Gregory 4/06
Post Reproduction and Menopause
Condition Total White Black Hispanic Asian Other
Menopause
Median age51.4 51.4 51.4 51.0 51.8 JA
51.4 CH
---
Pelvic prolapse (/1000)
2.1
Incontinence GUI % 59 29 8 14
DI% 15
Caucasians have higher rates of prolapse, incontinence—likely ascertainment Bias; Caucasians more likely to seek treatment for these conditions
![Page 33: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/33.jpg)
KD Gregory 4/06
Post Reproduction and MenopauseCondition Total White Black Hispanic Asian Other
Cancer IncidenceBreast 135.8 140.8 120.8 83.6 102.0 54.4
Cervix 9.1 8.8 12.3 16.1 8.6 ---
Ovary 16.7 17.6 11.8 12.4 13.1 ---
Uterus 24.3 25.6 17.3 15.3 18.0 ---
Cancer DeathsBreast 27.2 35.9 17.9 12.5 14.9
Cervix 2.7 5.9 3.7 2.9 2.9
Ovary
Uterus
![Page 34: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/34.jpg)
KD Gregory 4/06
So What Can Be Done To Close The Gap?
Healthand
FunctionDisease Health
Care
PhysicalEnvironment
GeneticEndowment
Well-Being Prosperity
IndividualResponse- Behavior- Biology
SocialEnvironment
Dynamic interaction between social and medical forces
Some of the differences can be accounted for by behavior—potentially modifiable
Will require a strategic combination of prevention and intervention across the life span and at multiple levels (individual, family/community, work, public policy) to close the gap in pregnancy and women health outcomes
![Page 35: Leading The Quest For Health Reproductive Health Disparities” A Lifespan Approach Kimberly D. Gregory MD, MPH Associate Professor Cedars Sinai Medical](https://reader036.vdocuments.us/reader036/viewer/2022062518/56649e355503460f94b23702/html5/thumbnails/35.jpg)
KD Gregory 4/06