ladisa, curriculum vitae - marquette university · curriculum vitae present positions: associate...

Oct. 1, 2018

JOHN F. LA DISA, JR., Ph.D.

CURRICULUM VITAE Present Positions: Associate Professor with Tenure - Marquette University and

Medical College of Wisconsin, Department of Biomedical Engineering

Director of Graduate Studies - Marquette University/Medical College of Wisconsin Department of Biomedical Engineering

Director - Laboratory for Translational, Experimental and Computational Cardiovascular Research (CV T.E.C. Lab)

Director - Marquette Visualization Laboratory (MARVL)

Adjunct Faculty - Children's Hospital of Wisconsin, Herma Heart Center

Adjunct Professor of Medicine - Medical College of Wisconsin, Department of Cardiovascular Medicine

Adjunct Professor of Physiology - Medical College of Wisconsin

Adjunct Professor of Pediatrics - Medical College of Wisconsin

Address: Marquette University Engineering Hall, Room 311 1637 West Wisconsin Avenue Milwaukee, WI 53233

Telephone: 414- 288-6739 (office) 414- 213-1121 (home)

Facsimile: 414- 288-7938

Electronic Mail: [email protected]

Websites: http://www.eng.mu.edu/cvtec/ http://www.eng.mu.edu/vizlab/ EDUCATION AND TRAINING

Postdoctoral Scholar, Pediatric Cardiology, Stanford University, CA, 2004-2006 Ph.D., Biomedical Engineering, Marquette University, Milwaukee, WI, 2004 M.S., Biomedical Engineering, Marquette University, Milwaukee, WI, 2001 B.S., Biomechanical Engineering, Marquette University, Milwaukee, WI, 2000

RESEARCH AND PROFESSIONAL EXPERIENCE

Associate Professor of Biomedical Engineering - Marquette University, Milwaukee WI 2013-present

Assistant Professor of Biomedical Engineering - Marquette University, Milwaukee WI 2007-2013

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Postdoctoral Scholar - Department of Pediatrics, Division of Pediatric Cardiology, Stanford University, Stanford, CA, 2004-2006

Research Technician - Department of Anesthesiology Research, Medical College of Wisconsin, Milwaukee, WI, 2001-2004

Laboratory Assistant - Department of Anesthesiology Research, Medical College of Wisconsin, Milwaukee, WI, 1998-2001

Research and Development & Quality Assurance Cooperative Education Student - Boston Scientific Corporation, Maple Grove, MN, 1997-99

AWARDS AND HONORS

Received since accepting faculty position at Marquette University Best use of stereoscopic content in a presentation - IS&T Electronic Imaging:

Stereoscopic Displays & Applications XXVII, San Francisco Feb 18, 2016 Participant for the Inaugural Summer 2015 Milwaukee I-Corps program 2015 40 Under 40 – Milwaukee Business Journal, Feb 20, 2015 2012 Editor's Choice list (1 of 9 papers) for Optimization of cardiovascular stent

design using computational fluid dynamics by TJ Gundert, AL Marsden, W Yang, JF LaDisa, Jr. J Biomech Eng 2012 Jan;134(1):011002

2012-13 e-learning Faculty Fellowship - Marquette University Center for Teaching and Learning. January 1, 2013 - December 31, 2013

Young Engineer of the Year Award - STEM Forward (formerly Engineers & Scientists of Milwaukee), February 16, 2012

Rising Star Award - Marquette Chapter of Sigma Xi, April 7, 2010 Featured in Milwaukee Magazine’s The Next Generation: New leaders under 40 who

will change Milwaukee. January 2009. Best Technology Business Plan Award Winner - 6th Annual Kohler Center for

Entrepreneurship Business Plan Competition, Marquette University, April 2008

Received prior to accepting faculty position at Marquette University 3rd Place - 2nd Annual Governor’s Business Plan Contest (Biomedical Sciences

Division), Wisconsin Technology Council, June 2005 Grand Prize, Alumni and Vox Populi Award Winners - 3rd Annual Kohler Center for

Entrepreneurship Business Plan Competition, Marquette University, April 2005 NSF Fellow - International Summer School on Biocomplexity from System to Gene,

Dartmouth College, July 19-25, 2003 Caroline tum Suden/Francis Hellebrandt Professional Opportunity Award - American

Physiological Society, January 2003 Student Travel Award - Biomedical Engineering Society, October 2002 Alpha Sigma Nu Graduate Student Scholarship - Marquette University, July 2001 Graduate Student Industrial Fellowship, Boston Scientific Corporation, June 2000 Alpha Eta Mu Beta - National Biomedical Engineering Honor Society, Marquette

University, 2000 Pi Mu Epsilon - National Mathematics Honor Society, Marquette University, 1999 Alpha Sigma Nu - National Jesuit Honor Society, Marquette University, 1999 Engineering Deans List - fall ‘96, spring ‘97, spring ‘98, fall ’98, spring ’99, spring ’00,

fall ’01, and fall ’02.

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ACADEMIC SERVICE AND PROFESSIONAL ACTIVITIES

Committees and University service: Lafferty Professorship - Opus College of Engineering, Marquette University, 2017-

2019

Marquette University/Medical College of Wisconsin Joint Department of Biomedical Engineering Founding Chair Search Committee, 2016-18

Director of Graduate Studies - Dept. of Biomedical Engineering, 2016 - present

Marquette University Dept. of Mechanical Engineering Chair Search Committee, 2016-17

Greenheck Endowed Chair in Design and Manufacturing Committee, 2014-16 Opus College of Engineering Committee

Student-Centered Active Learning Educator Committee, 2014 -15 Opus College of Engineering Committee

University Committee on Teaching, 2014-15

University Board of Graduate Studies Committee, 2014-2015, 2016 - present

Gap Analysis Planning Committee: Kohler Center for Entrepreneurship Marquette University, February 2012 to present - committee composed of faculty, staff, alumni and business personnel working with the Market Strategy Group on future planning efforts that highlight key gaps the center could address.

Leadership role for the Discovery Learning Complex Visualization facility, 2010 to present - Identifying pertinent applications, required hardware and software, and usage policies for potential users throughout the Marquette community

Core Evaluation Committee for the Clinical and Translational Science Institute (CTSI), 2011 - committee comprised of directors, users, and representatives of research groups, departments, and centers CTSI-affiliated institutions that evaluates performance, monitors usage, and make recommendations to the oversight advisory committee regarding expansion or discontinuation of cores.

College of Engineering Opus Dean Search Committee Member, 2009-10

Faculty Seminar in Catholic Identity – Participant, Spring 2008

Student Advising - curriculum guidance for ~ 10-12 students each semester

Undergraduate Committee - Dept. of Biomedical Engineering, 2008 – present

Senior Design Team Mentor Fall 2007 - B18: Medication Scheduling System Fall 2008 & Spring 2009 - B16: Medication Spinal Rod Cutter Fall 2009 & Spring 2010 - B13: Laparoscopic Surgery Simulator Fall 2011 & Spring 2012 - B5: Rubber Dam Tooth Clamp for Dental Procedures Fall 2012 & Spring 2013 - B22: Automated Counting System for the Operating Room Fall 2013 & Spring 2014 - B31: Low Cost Ventriloscope

Fall 2014 & Spring 2015 - B36: Enabling Use of Real Diagnostic Devices to Measure Vital Signs of Mannequins and People

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Fall 2015 & Spring 2016 - Immersive Cycling Initiative Fall 2016 & Spring 2017 - MRI Augmented Reality project Fall 2017 & Spring 2018 - Assisted Living in Virtual Environments (ALIVE) project

Memberships in professional societies:

Cancer Center at the Medical College of Wisconsin - Affiliate member Cardiovascular Center at the Medical College of Wisconsin - Affiliate member American Physiological Society (#44909) American Society of Mechanical Engineers - Bioengineering Division (#7818651) Biomedical Engineering Society (#5619) IEEE Division of Engineering in Medicine and Biology Society (#41527494) Society for Experimental Biology and Medicine (#22622) Sigma Xi Scientific Research Society

Peer-reviewed journal affiliations:

Thoracic Surgery Editorial Board Member - Clinics in Surgery, 3/9/2016 - present Associate Editor - ASME Journal of Medical Devices, 8/1/2013 - 8/1/2016 Frontiers in Pediatric Cardiology - Review Editorial Board Member, 2012 - present Ad-hoc journal reviewer: AJP-Heart Circ Physiol, Anesthesiology, Annals of

Biomedical Engineering, BioMedical Engineering OnLine, Cardiovasc and Intervent Radiol, Circulation, J Applied Physiol, J Biomechanics.

Health Research Board in Ireland - grant reviewer 2005 McGill Journal of Medicine - Junior Editor, 2002-2003

Invited scientific service:

Advisory Board Member, NEH Digital Humanities Advancement Grant, "Transparency to Visibility Network Visualization in Humanities Research." Submitted Jan. 2018

NIH Peer Reviewer - Small Business: Cardiovascular Sciences ZRG1 CVRS-C 10 ad hoc member: 7/25-26/15; 11/19-20/15; 11/10-11/16; 7/13-14/17; 3/15-16/18

Session Chair - 5th International Conference on Engineering Frontiers in Pediatric and Congenital Heart Disease, Orlando, June 2016

Judge - 2014 HACKATHON competition sponsored by Direct Supply Reviewer - Transcatheter Cardiovascular Therapeutics (TCT) 2014, 2016 Reviewer - 7th World Congress of Biomechanics Site Coordinator - Virtual School of Computational Science & Engineering (VSCSE)

Science Visualization Summer School, Marquette University, Aug 24, 2015 Faculty member for the 2012 Lifeline Vascular Access - Physician Operators Forum,

Denver, April 2012 Session Chair - Annual Meeting of the Biomedical Engineering Society: Systems

Biology, Bioinformatics & Computational Bioengineering, Hartford, October 2011 Session Chair - ASME Bioengineering Division, Summer Bioengineering

Conference: CFD Modeling, Farmington, June 2011 American Heart Association Peer Reviewer - 2011 - present Session Chair - ASME Bioengineering Division, Summer Bioengineering

Conference: Cardiovascular Design and Devices I, Naples, June 2010 Program Committee Member & Session Chair - SPIE Medical Imaging: Biomedical

Applications in Molecular, Structural & Functional Imaging, San Diego 2010

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Member of Fluids Committee - ASME Bioengineering Division, Summer Bioengineering Conference, 2009 - present

Faculty member for the 2008 IMAGING & PHYSIOLOGY Summit - sponsored by the CardioVascular Research Foundation (CVRF), Seoul, Korea, November 2008

TEACHING

Since accepting faculty position at Marquette University Instructor for BIEN 6931 Topics in Biomedical Engineering: Patient-Specific

Computational Modeling - Fall 2017 Instructor for BIEN 6931 Topics in Biomedical Engineering: Immersive Visualization

of Scientific Data - Spring 2017 Instructor for BIEN 4720/5720 (formerly BIEN183): Cardiopulmonary Mechanics -

Spring, 2007, 2008, 2009, 2011, 2016, 2018 & Fall 2012, 2013, 2014, 2016, 2017 Co-Instructor for BIEN1100 (formerly BIEN002): Introduction to Biomedical

Engineering Methods 2 - Spring, 2007-16 (immersive visualization lab added Spring of 2014)

Instructor for BIEN4400/5400 (formerly BIEN186): Transport Phenomena for Biomedical Engineers - Fall 2007 - 2012, 2013, 2014, 2017 and Spring 2010, 2012, 2014, 2015 and 2016 (Educational research project on demonstration/laboratory effectiveness with John Borg PhD in Fall and Spring 2014, and Spring 2015)

Instructor for BIEN210: Biofluid Mechanics - Fall, 2008 Sabbatical - Fall 2015

Prior to accepting faculty position at Marquette University Co-Instructor for BIOE284A/ME284A: Cardiovascular Bioengineering - Stanford

University, Stanford, CA, Autumn, 2005 and Autumn, 2006 Course Moderator and Administrator for BIOE390/MED289: Introduction to

Bioengineering Research - Stanford University, CA, Autumn, 2005 and Fall 2006 Choice Instructor and creator of “How the Body Works” - De Marillac Middle School,

San Francisco, CA, 2005 Guest Lecturer for Physiology, Media College Prep High School, Oakland, CA, 2005

RESEARCH MENTORSHIP, THESIS AND DISSERTATION COMMITTEES

Mentees since accepting faculty position at Marquette University:

Undergraduate Research Mentor: William Wang (B.S. in Biomedical Engineering 2013 - Marquette University)

Mia Helfrich (B.S. in Biomedical Engineering 2013 - Brown University)

Michael Kamykowski (B.S. in Biomedical Engineering 2014 - Marquette University)

Daphne Gutierrez (B.S. in Biomedical Engineering 2015 - Marquette University)

Keelia Doyle (B.S. in Biomedical Engineering 2015 - Marquette University)

• NSF Fellow - 12th International Summer School on Biocomplexity and Biodesign: from Gene to System, June 23-9, 2013 Istanbul, Turkey

Matthew Jung (B.S. in Biomedical Engineering 2016 - Marquette University)

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Elise Hahn (B.S. in Biomedical Engineering 2018 - Marquette University)

Sophia Shanahan (B.S. in Biomedical Engineering 2018 - Marquette University)

Kathryn Repp (B.S. in Biology 2018 - Wake Forest University) Master's Thesis Chair and Primary Advisor:

Andrew Williams M.S. (B.S. in Biomedical Engineering from Marquette University), Quantifying Hemodynamic Changes Caused by Stenting of Coronary Bifurcation Lesions Using Realistic Computational Fluid Dynamics Models. December 2008

• BS/MS student in Biomedical Engineering at Marquette University

• Participant for the 2007 Emerging Entrepreneurs in Biomedical Technology Workshop - Stanford University, October 5-6, 2007

• currently a Mechanical Design Engineer with Creation Technologies

Ronak Dholakia M.S. (B.S. in Biomedical Engineering from University of Mumbai), Numerical Modeling of Hemodynamics in the Thoracic Aorta and Alterations by Dacron Patch Treatment of Aortic Coarctation. December 2009

• currently a PhD student and Research Specialist with the Cerebrovascular Research Center at Stony Brook University Medical Center

Sara Nomeland M.S. (B.S. in Biomedical Engineering from Michigan Tech), Image-based quantification workflow for coronary morphology: a tool for use in next-generation bifurcation stent design. August 2010

• Recipient of the 2009 Maurice L. Madden Biomedical Engineering Fellowship

• currently an Engineer with MED Institute, Inc. (Cook Medical)

Timothy Gundert M.S. (B.S. in Biomedical Engineering May 2009), Improving cardiovascular stent design using patient-specific models and shape optimization. December 2011


• Awarded 3rd Place in the Bachelor's Student Paper Competition of the ASME Summer Bioengineering Conference (Biotransport, Tissue Engineering, and Cellular Biomechanics Category): Presented at the Resort at Squaw Creek Lake Tahoe, CA June 17-21, 2009

• Awarded 2nd Place in the Master’s Student Paper Competition of the ASME Summer Bioengineering Conference (Solid Mechanics, Design and Rehabilitation Engineering Category): Presented at the Grande Beach Resort, Naples, FL June 16-19, 2010

• MAGS Distinguished Master's Thesis Award nominee for Marquette University

• currently a R&D Engineer at Medtronic - Renal Denervation (F/K/A Ardian)

David 'DJ' Quam M.S. (B.S. in Biomedical Engineering May 2009), Advanced visualization and intuitive user interface systems for biomedical applications. May 2012


• accepted an Engineer position as part of the Quality/Regulatory Leadership Program at GE Healthcare

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Sung Kwon (B.S. in Biomedical Engineering from the University of Minnesota), Quantification of local hemodynamic alterations caused by virtual implantation of three commercially-available stents for the treatment of aortic coarctation. December 2013

• Quality Engineer at Baxter Healthcare

Joshua Hughey (B.S. in Biomedical Engineering from the University of Missouri), Computational evaluation of shear stress and restenosis in stented coronary arteries using optical coherence tomography

May 2014

• 2nd place in the MS level poster competition at the World Congress of Biomechanics Conference (Biofluids division) - Boston July 6-11, 2014

Daniel Greenheck (B.S. in Biomedical Engineering from the University of Wisconsin - Madison), August - December 2013

Ali Aleiou (B.S. in Biomedical Engineering from the University of Minnesota), Evaluating wall shear stress indices to uncover stimuli for restenosis and

malapposition in stented coronary arteries July 2017

Brandon Wegter (B.S. in Materials Science from the University of Wisconsin - Milwaukee),

Elucidating the mechanical, structural, functional, and molecular mechanisms involved in irreversible vascular changes in aortic coarctation

November 2017

• Best Poster Award at the 5th International Conference on Engineering Frontiers in Pediatric and Congenital Heart Disease, Orlando June 9-10, 2016

John Venn (B.S. in Biomedical Engineering from Michigan State), Immersive visualization in biomedical computational fluid dynamics and didactic

teaching and learning May 2018

Doctoral Dissertation Primary Advisor: Dave Wendell (B.S. in Electrical Engineering from Purdue University), Incorporating

the Aortic Valve into Computational Fluid Dynamics Models Using Phase-Contrast MRI and Valve Tracking. December 2011

• Recipient of an American Heart Association Predoctoral Fellowship - Greater Midwest Affiliate

• currently a Postdoctoral Scholar at the Duke Cardiovascular Magnetic Resonance Center (DCMRC) of Duke University Medical Center PIs: Raymond Kim, MD and Robert Judd, PhD

Arjun Menon (B.S. in Biomedical Engineering from the University of Minnesota), Quantifying the impact of altered hemodynamics and vascular biomechanics to changes in structure and function in native and corrected aortic coarctation.

May 2012

• currently a Postdoctoral Scholar in the Leon H. Charney Division of Cardiology, Department of Medicine, New York University School of Medicine PI: Edward A. Fisher, PhD, MD, MPH

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Hongfeng 'Nick' Wang (Doctor of Veterinary Medicine and M.S. in Embryonic Engineering, Northwest A&F University, China; M.S. in Genetics, Mississippi State University), Vascular changes in Type 2 Diabetes Mellitus: application to restenosis to restenosis after stenting. May 2013

• Recipient of the Chinese Government Award for Outstanding Students Abroad by China's Scholarship Council

• Recipient of an Arthur J. Schmitt Fellowship Award

• currently an Embryologist at Florida Institute for Reproductive Medicine

Thomas Dienhart (B.S. in Biomedical Engineering from Michigan Tech), 2012 - 2013

• Awarded 3rd Place in the Graduate Division of the Sigma Xi 2013 Student Research Showcase (Engineering Section)

• Applicant for an American Heart Association Predoctoral Fellowship - Greater Midwest Affiliate

Scott Loberg (B.S. in Biology from Winona State University) August - December 2013

Benjamin R. Dickerhoff (B.S. & M.S. in Biomedical Engineering from the University of Iowa)

December 2013 - present

• M.S. Thesis advisor - Madhavan Raghavan Ph.D. - University of Iowa

• Sigma Xi Grants-in-Aid of Research applicant

Kathleen B. Bazan (B.S. in Biomedical Engineering from the Milwaukee School of Engineering)

July 2015 - April 2016

• PhD student in the Department of Physiology at the Medical College of Wisconsin

• Applicant for an American Heart Association Predoctoral Fellowship - Greater Midwest Affiliate

Atefeh (Ati) Razavi (B.S. in Mechanical Engineering, Yazd University, Iran; M.S. in Mechanical Engineering, Isfahan University of Technology, Iran; M.S. in Biomedical Engineering, University of Arkansas)

August 2015 - present

Jesse Gerringer (B.S. in Bioengineering, University of Illinois at Chicago) August 2016 - present

Andrew Palm (B.S. in Physics, Augustana College; M.S. in Physics, Northern Illinois University)

January 2017 - present Doctoral Dissertation Committee Member (Department of Biomedical Engineering at Marquette University unless indicated:

John A. Wheeldon BSEE MSEE, The Role of Mechanical Changes in the Aging Cervical Spine, defended November 2008

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Jason J. Hallman PhD, Detrimental Thoracoabdominal Interaction with Llateral Airbag Restraints, completed December 2010

Zhuohui Gan PhD, Quantitative Evaluation of Redox Processes in the Intact Rat Lung and Cultured Pulmonary Artery Endothelial Cells and the Effect of Hyperoxia, completed December 2011

Karl Stamm MS, Department of Mathematics, Statistics, and Computer Science - Marquette University, Development of a Method to Identify Compensatory Pathways Using Heuristic Genomic Epidemiology completed August 2016

Hongfeng Ma, Motion artifact evaluation of coronary CT angiography images, completed December 2017

John Bukowy, Department of Physiology - Medical College of Wisconsin, Distribution of Renal Blood Flow as a Predictor of Pressure Outcomes and Glomerular Injury defended February 2018

Xiao Zhang, Department of Biomedical Engineering - Marquette University, defense anticipated May 2018

Master's Thesis Committee Member: Daniel Stassi BS, Automatic Selection of Optimal Cardiac Phase for Coronary CT

Angiography, completed July 2014

Sally Lin BS, Characterization of histological changes in the microvasculature of rate skeletal muscle after spinal cord injury, completed May 2017

Postdoctoral and Visiting Scholars: Laura Ellwein, Ph.D. (B.S. in Chemical Engineering from University of Wisconsin -

Madison; Ph.D. in the Interdisciplinary Physiology Concentration of Applied Math at North Carolina State University; Thesis advisor: Mette S. Olufsen, Ph.D.)

2009-2012

• Recipient of an American Heart Association Postdoctoral Fellowship - Greater Midwest Affiliate

• currently an Assistant Professor of Mathematics (tenure-track) at Virginia Commonwealth University

Mary Draney Blomme, Ph.D. (B.S. in Biomedical Engineering from Marquette University; Ph.D. in Mechanical Engineering from Stanford University, Thesis advisor: Charles A. Taylor, Ph.D.)

August 2014 - July 2015

Harkamaljot ‘Rocky’ S. Kandail, Ph.D. (Ph.D. in Chemical Engineering from Imperial College London, UK; Thesis advisor: Xiao Yun Xu Ph.D.)

August 2016 - August 2017

• Postdoctoral Researcher at Eindhoven University of Technology

Mentees prior to accepting faculty position at Marquette University: Paul Larsen (Medical Student, Tulane School of Medicine, B.S. from Washington

University in St. Louis, 2007)

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Nicholas Telischak (Medical Student, Dartmouth Medical School, 2007) Dominic Lai (Undergraduate Student, Biomedical Sciences, Marquette University,

2004, currently a Pharmacy resident) Dunbar Alcinor (Medical Student, Medical College of Wisconsin, 2002-03, currently

Neurosurgery Resident at Alleghany General Hospital in Pittsburgh, PA) Eric Kersten (Undergraduate Student, Biomedical Engineering, Northwestern

University, 2002, currently an Engineer with GE Medical Systems) Ankit Shah (Graduate Student, Biomedical Engineering, Marquette University, 2002, currently a Wharton MBA student - University of Pennsylvania)

GRANTS AND CONTRACTS Funding to date: direct costs (DC): $3,994,909; with indirect costs (wIDC): $4,085,909 Percent effort indicated after the role for each grant.

Received since accepting faculty position at Marquette University:

Current: Medical College of Wisconsin Digestive Disease Center, “Immersive virtual reality

caregiver training in pediatrics feeding disorders”. DC: $20,000 wIDC: $20,000 5/1/18-4/30/19 Role: Co-I, P. Goday (PI)

Medical College of Wisconsin Cancer Center, “Pilot study for the development and implementation of a virtual reality-based breast cancer patient radiation education and anxiety mitigation program”.

Multi PI Award Program DC: $40,000 wIDC: $40,000 5/1/18-4/30/19 Role: Co-PI (w/ C. Bergom)

NIH, “Mechanisms of morbidity after correcting aortic coarctations of varying severity”. R01 - Research Project Grant

DC: $1,112,694 wIDC $1,512,870 7/1/18-4/30/22 Role: PI (1.35 cal + 2 summer mo)

Opus College of Engineering, “A virtual reality patient education program for radiotherapy-based breast cancer treatment” Undergraduate Research Fellowship Program

DC: $5,000 3/01/18-12/31/18 Role: Mentor, S. Shanahan (PI)

Little Hearts for Life, “Role of cardiac MRI and computational models for post-operative risk stratification in children with intramural anomalous aortic origin of coronary arteries (AAOCA)”

DC: $12,000 1/01/18-12/31/18 Role: Co-I, P. Frommelt (PI)

CTSI of Southeastern Wisconsin, “Image-based modeling and RNA sequencing to predict maturation of arteriovenous fistulas created for hemodialysis” Translational Opportunity Grant of the Pilot and Collaborative Clinical and Translational Research Grants program

DC: $50,000 4/1/17-3/31/19 Role: PI (0.35 summer mo)

Marquette University, “ALIVE: the Assisted LIving Virtual Environment”. Innovation Fund DC: $79,858 7/1/15-6/30/18 Role: faculty advisor (Student PIs: A. Barrington, M. Barrowclift, T. Pawlicki)

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Pending: NIH, “Computational identification of mechanical contributors to restenosis and

thrombosis after stenting”. R01 - Research Project Grant DC: $1,308,385 wIDC 1,965,419 4/1/19-4/31/24 Role: PI (1.8 cal + 1-2 summer mo)

Completed CTSI of Southeastern Wisconsin, “Developing technologies for rapid production of

individualized models of congenital cardiovascular diseases to facilitate clinical treatment” Translational Opportunity Grant of the Pilot and Collaborative Clinical and Translational Research Grants program

DC: $50,000 4/1/17-3/31/18 Role: Co-I (1 summer mo) A Greene (PI)

Marquette University, “Partnerships for Excellence through Advanced Visualization”. Innovation Fund DC: $164,250 7/1/15-6/30/18 Role: PI

Marquette University Committee on Research Regular Research Grant Programs, “Correlating wall shear stress to cellular proliferation in the setting of drugs used with current coronary artery stents”.

DC: $6,000 1/01/17-12/31/17 Role: PI

Marquette University Opus College of Engineering, “Modeling Chemical Deposition in the Human Airway from Electronic Cigarettes”

Legacy Initiative Research Seed Grant DC: $75,000 wIDC $75,000 7/1/16-12/31/17 Role: Co-I, S. Singer (PI)

Medical College of Wisconsin Center of Imaging Research Intramural Pilot Award, “Magnetic Resonance Imaging for an experimental model of aortic coarctation”

DC: $5,000 4/27/16-4/26/16 Role: PI

Marquette University College of Engineering Summer Undergraduate Research Program, “2016 Summer Virtual Reality aiding in the Research of Stroke Rehabilitation”

DC: $4,820 5/27/16-8/9/16 Role: co-PI (with S. Schindler-Ivens)

Aurora Healthcare, Inc., “Evaluation of and prediction of complications after transcatheter aortic valve replacement using computational methods”.

Sullivan Cardiac Research Award for Residents and Fellows DC: $29,952 1/1/16-12/31/16 Role: Co-I (20% cost shared), Trivedi (PI)

American Heart Association, “Mechanistic analysis of mechanical alterations to improve therapeutic interventions for aortic coarctation”.

Grant-in-Aid Midwest Affiliate DC: $129,832 wIDC: $142,816 7/1/15-6/30/17 Role: PI (1 summer mo)

Kobe University School of Medicine, "Optical coherence and computed tomography for evaluation of wall shear stress and thrombus potential in coronary arteries after stenting". Educational Research Agreement Supplement

DC: $37,000 01/01/15-5/31/16 Role: PI (as needed)

NSF University of Wisconsin-Milwaukee I-Corps Site, “Immersive Fitness by MARVL”. Summer 2015 I-Corps Program

DC: $2,400 4/1/15-7/31/16 Role: project PI, Avdeev (site PI)

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Marquette University College of Engineering (CoE), "Proposal for the purchase of an ILUMIEN optical coherence tomography (OCT) and pressure measurement system" CoE RFP for Research Equipment - revised

DC: $95,500 Role: PI

Marquette University Office of Research & Innovation, Faculty Development Award DC: $900 4/7/2015 Role: PI (as needed)

Kobe University School of Medicine, "Optical coherence and computed tomography for evaluation of wall shear stress and thrombus potential in coronary arteries after stenting". Educational Research Agreement

DC: $61,130 wIDC: $92,000 8/27/12-8/26/14 Role: PI (as needed)

Marquette University College of Engineering Student Centered Learning Project, “Fluid Dynamic Design and Build Demonstration”

DC: $11,240 6/1/14-8/22/14 Role: Co-I (as needed) J Borg (PI)

Marquette University Center for Teaching and Learning “IDIVE, an integrated digital immersive virtual environment for enhancing engineering education”.

2012-13 e-learning Faculty Fellowship DC: N/A 1/1/13-12/31/13 Role: PI (1.8 cal)

Children's Hospital of Wisconsin, "Next-generation visualization of data and CFD results". Educational Research Agreement

DC: $20,770 wIDC: $28,345 1/ 1/12-8/31/13 Role: PI (as needed)

Marquette University College of Engineering Summer Undergraduate Research Program, “Optimizing flow patterns over vascular cells: reducing cellular proliferation for application to drug eluting stents”


NIH, “Cardiovascular, Lung, and Blood Computation Model Library”. Contract to Open Source Medical Software Corporation DC: $83,584 wIDC:$117,353 5/30/11-5/29/13 Role: Co-I(2 summer mo) N Wilson (PI)

Marquette University Office of the Provost, “The Use of the IDIVE - An Integrated Digital Immersive Virtual Environment to Facilitate Nursing Student

Development of Clinical Reasoning”. Assessment Mini-Grants DC: $2,500 1/1/12-6/30/12 Role: Co-I(as needed) K Goepfert(PI)

NIH, “Quantifying altered hemodynamics in response to stenting for aortic coarctation”. R15 - Academic Research Enhancement Award

DC: $158,936 wIDC:$241,420 4/1/09-4/30/12 Role: PI (1 summer mo)

Medical College of Wisconsin, “CFD Modeling for Pediatric Cardiovascular Disease”. Contract through Margaret Samyn MD.


American Diabetes Association, “A novel interdisciplinary approach to characterize and minimize vascular changes contributing to restenosis after stenting in type 2 diabetes mellitus” Junior Faculty Award

DC: $357,609 wIDC:$411,251 7/1/08-6/30/11 Role: PI (2.4 cal + 2 summer mo)

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CTSI of Southeastern Wisconsin, “Computational Cardiology: Translating theoretical and subject-specific computational fluid dynamics results into a specialized stent for coronary artery bifurcation lesions” Translational Opportunity Grant of the Pilot and Collaborative Clinical and Translational Research Grants program


Medtronic Corporation, “CFD Stent Analysis”. Educational Research Agreement. DC: $8,316 wIDC $12,516 8/1/10-9/30/10 Role: PI (as needed)

Alvin & Marion Birnschein Foundation, “A coupled clinical and computational approach to determine important design characteristics of a novel stent specifically designed for the progressive treatment of aortic coarctation”


NIH, “A novel cardiovascular stent for the intrinsic reduction of restenosis and thrombus formation”, Small Business Technology Transfer (STTR) Award - R41

DC: $99,983 8/1/08-7/31/09 Role: PI

Biomedical Engineering Research Initiative for Undergraduate Students, “Developing Cardiovascular Content for the Discovery World HIVE Visualization Facility”


Committee on Research Summer Faculty Fellowship and Regular Research Grant Programs, “Engineering a novel treatment for the reduction of long-term morbidity in children with aortic coarctation”.

DC: $11,500 7/01/08-12/31/08 Role: PI (0.75 summer mo)

Children’s Research Institute “Cardiac Magnetic Resonance Imaging (cMRI) Assessment of Early Atherosclerosis in Pediatric Type I Diabetic (T1DM), Type 2 Diabetic (T2DM) and Metabolic Syndrome Patients”

DC: $74,864 1/01/08-12/31/08 Role: Co-I (as needed), M Samyn (PI)

Alvin & Marion Birnschein Foundation, “A coupled clinical and computational approach to determine important design characteristics of a novel stent specifically designed for the progressive treatment of aortic coarctation”


Marquette University College of Engineering Research Incentive Program, “Computational assessment of adverse hemodynamic alterations and subsequent restenosis caused by changes in distal resistance resulting from type II diabetes mellitus” DC: $8,357 1/01/08-6/30/08 Role: PI (as needed)

NIH, “Patient-specific computational modeling of altered hemodynamics, arterial deformation and morbidity induced by aortic coarctation and subsequent surgical or catheter-based repair”. Loan Repayment Programs

DC: $8,037 7/1/06-6/30/08 Role: PI (N/A)

Biomedical Engineering Research Initiative for Undergraduate Students, “Development of a phantom and offline postprocessing techniques for use with 3D ultrasound data of the human carotid bifurcation”

DC: $2,000 1/01/08-5/31/08 Role: co-PI w T. Gilat-Schmidt (N/A)

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Received prior to accepting faculty position at Marquette University: Stanford University, “Computational Modeling of Alterations in Vascular

Hemodynamics for Optimization of Surgical and Catheter-Based Therapies and Long-Term Outcomes in Aortic Coarctation”. Dean's postdoctoral fellowship,

DC: $40,000 2004-05 Role: PI (12 cal)

Sigma Xi Scientific Research Society, “Local Vascular Geometry and Shear Modulated Mitotic Expression After Chronic Stenting”. Grants-in-Aid of Research, dissertation project supply stipend

DC: $1,000 2003 Role: PI (N/A)

Boston Scientific Corporation, "In Vivo and Computational Fluid Dynamics Modeling of Hemodynamic Changes Induced by Coronary Stenting” Graduate Thesis Project, tuition and stipend

DC: ~$30,000 2000-01 Role: PI ( 12 cal)

PATENTS AND DISCLOSURES

Progressive expansion diameter stent, Disclosed to Stanford University April 18, 2005.

Apparatus and method for minimizing flow disturbances in a stented region of a lumen - #US20080140179, published June 12, 2008 (abandoned after second final rejection)

Gesture-based visualization system for biomedical imaging and scientific datasets – patent application submitted by Marquette University on April 30, 2014.

Ultra-High-Resolution Content for Immersive Fitness and Wellness, Disclosed to Marquette University Oct. 20, 2015.

PRESENTATIONS (students and trainees indicated in boldface)

Offered since accepting faculty position at Marquette University:

National: “Building strategies for uncertain futures.” Strategy & Innovation World Forum. Invited

presentation. San Francisco. Sept. 21, 2017.

“An efficient approach to playback of stereoscopic videos using a wide field-of-view.” IS&T International Symposium on Electronic Imaging 2016 - Stereoscopic Displays & Applications Conference. Invited presentation. San Francisco. Feb. 17, 2016. Awarded best use of stereoscopic content in a presentation

“Optimizing mechanical stimuli around stents to reduce restenosis and thrombosis: MIT/Harvard Collaboration Discussion.” Edelman lab meeting - Massachusetts Institute of Technology. Boston. July 9, 2014.

"Recent progress in the use of experimental and computational tools to optimize flow patterns around stents and reduce coronary artery restenosis" Department of Mechanical Engineering & Materials Science - University of Pittsburgh, Oct. 15, 2013

"Stent architecture/design - does it matter for restenosis?" Invited presentation - Lifeline Vascular Access 2012 Physician Operators Forum, Denver, April 14, 2012

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"Hemodialysis, stenosis and Chronic Kidney Disease: An Engineer's Perspective" Invited presentation - Lifeline Vascular Access 2012 Physician Operators Forum, Denver, April 14, 2012

"The Success of Aortic Arch Surgery: An Engineer's Perspective" Invited presentation - American Heart Association (AHA) Scientific Sessions 2011: Cardiovascular Seminar entitled Biomedical Engineering Insights into Congenital Heart Disease, Orlando, FL, Nov. 15, 2011

“Coupling experimental and computational tools to quantify hemodynamic alterations introduced by stents” Invited presentation - CardioVascular Innovation Seminar (CVIS) series, Medtronic CardioVascular, Santa Rosa, CA, Jan. 19, 2011

“Aortic coarctation: recent developments in experimental and computational methods to assess treatments for this simple condition.” Invited presentation - 1st International Conference on Computational Simulation in Congenital Heart Disease, San Diego, Feb. 27, 2010

“A new image-based process for quantifying hemodynamic contributions to long-term morbidity in a rabbit model of aortic coarctation” offered by DC Wendell, RJ Dholakia, PM Larsen, AR Menon, JF LaDisa, Jr. SPIE Medical Imaging: Biomedical Applications in Molecular, Structural & Functional Imaging, San Diego, Feb. 2010

“Coupling clinical and computational resources to quantify hemodynamic alterations as indices of morbidity and engineer novel treatment strategies for carotid artery disease”, Invited presentation - Penner Biomechanics Seminar, Department of Mechanical Engineering, University of California - San Diego, May 20, 2009

“Coupling experimental, computational and translational resources for use in next generation stent design”, Invited presentation - Abbott Vascular, Santa Clara, August 10, 2007

International: "Recent advancements with patient-specific coronary artery stenting simulations for

bifurcation lesions." Invited presentation - 13th European Bifurcation Club (EBC) meeting, Brussels, forthcoming Oct. 12-13, 2018

"Patient-Specific Drug Elution Simulations in Stented Coronary Arteries Using a Combined Experimental-Numerical Scheme." 13th World Congress on Computational Mechanics / 2nd Pan American Congress on Computational Mechanics, New York, forthcoming July 22-27, 2018

"Analysis of hemodynamic stimuli, persistent vascular changes and gene expression in a rabbit model of human aortic coarctation and repair." Invited presentation - 4th International Frontiers Conference on Pediatrics and Congenital Heart Diseases. Sponsored by Stanford University and INRIA. Paris, France. May 21-22, 2014.

"Reducing restenosis in challenging coronary lesions: optimization-based treatment planning and follow-up using immersive visualization." Invited presentation - 9th International Symposium on Biomechanics in Vascular Biology and Cardiovascular Disease. Montreal, Québec - Canada, April 28-29, 2014.

“Combined use of imaging and computational techniques to investigate fluid dynamics in normal and stented coronary artery bifurcations” Invited presentation - IMAGING

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& PHYSIOLOGY Summit 2008, sponsored by the CardioVascular Research Foundation (CVRF), Seoul, Korea, November 22, 2008

Regional: “Determining the contribution of NPR3 variants to hypertension in treated coarctation

of the aorta patients” 41st Annual Midwest Pediatric Cardiology Society Conference Meeting, Saint Louis University School of Medicine - Sept. 7, 2017

“Application of material from BME505 Biofluids: Examples from the CV T.E.C. and MARVL facilities at Marquette University and the Medical College of Wisconsin” Biomedical Engineering Department, University of Wisconsin - Madison, April 26, 2017

“Hemodynamic stimuli, persistent vascular changes and gene expression in a model of aortic coarctation and repair” Biomedical Engineering Department Seminar, Purdue University, Oct. 28, 2015

"Developing immersive visualization content for interactive teaching, learning and research" Invited presentation - MBECC 2011: Visualization in Medicine Panel, Northwestern University, Evanston, IL, April 1, 2011

Local: “Coordinated roles for mechanical stimuli and NPR-C in coarctation-induced

hypertension” Children's Research Institute Research Conference, Children's Hospital of Wisconsin, Oct 6, 2017

“Mechanistic analysis of mechanical stimuli from aortic coarctation” Scientific External Advisory Committee review of the Herma Heart Center, Children's Hospital of Wisconsin, July 6, 2017

“Translational patient-specific computational modeling and visualization” Radiology Grand Rounds, Department of Radiology, Medical College of Wisconsin, May 1, 2017

“Analysis of hemodynamic stimuli, persistent vascular changes and gene expression in a model of aortic coarctation and repair” Physiology Department Seminar, Medical College of Wisconsin, Sept. 23, 2015

“The Marquette Visualization Lab: Enhancing research, teaching and outreach initiatives through immersive visualization” Invited presentation - Marquette University Faculty Tech Day, Sept. 15, 2015

“The MARquette Visualization Lab (MARVL): a new immersive environment for research, teaching and collaboration” Invited presentation - Mechanical Engineering MEEN Seminar Series, November 20, 2014

“The MARquette Visualization Lab (MARVL): a new immersive environment for research, teaching and collaboration” Invited presentation - Electrical Engineering and Computer Engineering (EECE) Colloquium, October 14, 2014

“Choices & Freedom: Finding Balance in Academic Life” Invited presentation - Marquette University Faber Center - Freedom and Choices in Academic Life Series, September 24, 2014

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“Merging engineering and medicine through immersive visualization” Invited presentation - Collaborative Research Symposium sponsored by the Biotechnology and Bioengineering Center of the Medical College of Wisconsin, July 18, 2014

“Computational cardiology: using optimization and advanced visualization to reduce restenosis in challenging coronary lesions” MCW REU Friday Morning Lecture Series, June 27, 2014

“Look on the bright side: Nobody’s getting funded, so why not collaborate?” Toward MCW BBC/Pathology Collaborations Seminar, June 26, 2014

“Reducing restenosis in challenging coronary lesions: optimization-based treatment planning and follow-up using advanced visualization techniques” Milwaukee Quick Pitch – A First Look Forum Event, May 29, 2014

“Your simulation ran...now what? Extracting simulation details using immersive visualization” High-Performance Computing seminar, Marquette University, April 9, 2014

“Analysis of hemodynamic stimuli, persistent vascular changes and gene expression in an experimental model of human aortic coarctation and repair” Visiting Faculty Seminar, Medical College of Wisconsin, Biotechnology and Bioengineering Center, April 8, 2014

“Cardiac magnetic resonance imaging assessment of early atherosclerosis in pediatric patients with Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, and Metabolic Syndrome” Invited co-presentation (with Margaret Samyn, MD) - Cardiovascular Translational Research Symposium, Clinical and Translational Research Institute (CTSI), January 9, 2009

“Leveraging current imaging techniques for next-generation medical diagnosis, monitoring and treatment” Invited presentation - Cultivating Innovation Symposium, GE Healthcare, Milwaukee, December 12, 2008

“Coupling clinical and computational resources to quantify hemodynamic alterations as indices of morbidity and engineer novel treatment strategies for carotid artery disease”, Invited presentation - Cardiology Grand Rounds, Department of Cardiovascular Medicine, Medical College of Wisconsin, February 12, 2008

Offered prior to accepting faculty position at Marquette University: “Coupling experimental and computational tools for use in next generation in stent

design”, Invited presentation - Medtronic Vascular, Santa Rosa, November 29, 2006

“Recent progress and future initiatives for quantifying hemodynamic alterations as indices of morbidity before and after repair of aortic coarctation”, Special Symposium on Aortic Coarctation, Children’s Hospital of Wisconsin, March 9, 2006

“Patient-specific modeling of altered hemodynamics and arterial deformation induced by coarctation of the aorta and subsequent stent implantation”, poster presentation, Biomedical Computation at Stanford (BCATS) Symposium, Oct. 15, 2005

“Distributions of wall shear stress influence neointimal hyperplasia after stent implantation in vivo” Biomedical Engineering Society Annual Meeting, Oct. 2004

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WHITE PAPERS

1. John F. LaDisa, Jr., with contributions by Michael S. Switzenbaum, Keith Rocheck and Brad Bonczkiewicz. Purchase Recommendations for the Visualization Laboratory in Engineering Hall - submitted to Robert H. Bishop PhD, OPUS Dean, College of Engineering, Marquette University, October 2012

2. John F. LaDisa, Jr., with contributions by Christopher M. Foley and Saeed Karshenas. Developing Interest, Content, Publicity and Expertise for an Advanced Visualization Facility - submitted to Stan Jaskolski, OPUS Dean, and Michael S. Switzenbaum, Professor and Executive Associate Dean, College of Engineering, Marquette University, August 2008

BOOK CHAPTERS

1. Margaret M Samyn, John F. LaDisa, Jr., Novel Applications of Cardiovascular Magnetic Resonance Imaging-Based Computational Fluid Dynamics Modeling in Pediatric Cardiovascular and Congenital Heart Disease. In Magentic Resonance Imaging. 2016 Editor: Christakis Constantinides, InTech

2. John F. LaDisa, Jr., Charles A. Taylor, Jeffrey A. Feinstein. Endovascular treatment strategies for coarctation of the aorta. In: Current Treatment of Thoracic Aortic Diseases. 2006. Editor: Herve Rousseau, Springer, pp. 363-374.

PEER-REVIEWED JOURNAL ARTICLES (students and postdocs in boldface)

Since accepting faculty position at Marquette University: 1. Harkamaljot S. Kandail, Setu D. Trivedi, Armaan C. Shaikh, Tanvir K. Bajwa,

Daniel P. O’Hair, Arshad Jahangir, John F. LaDisa, Jr. Impact of annular and supra-annular CoreValve deployment locations on aortic and coronary artery hemodynamics. J Mech Behav Biomed Mater. 2018 Oct; 86:131-142.

2. David C. Wendell, Ingeborg Friehs, Margaret M. Samyn, Leanne M Harmann, John F. LaDisa, Jr. Treating a 20 mm Hg gradient alleviates myocardial hypertrophy in experimental aortic coarctation. J Surg Res. 2017 Oct;218:194-201.

3. Laura Ellwein, Margaret M. Samyn, Michael Danduran, Sheila Schindler-Ivens, Stacy Liebham, John F. LaDisa, Jr. Toward translating near-infrared spectroscopy oxygen saturation data for the non-invasive prediction of spatial and temporal hemodynamics during exercise. Biomech Model Mechanobiol. 2017 Feb;16(1):75-96. doi: 10.1007/s10237-016-0803-4

4. David C. Wendell, Margaret M. Samyn, Joseph R. Cava, Mary M. Krolikowski, John F. LaDisa, Jr. The impact of cardiac motion on aortic valve flow used in computational simulations of the thoracic aorta. J Biomech Eng. 2016 Sep 1;138(9). doi: 10.1115/1.4033964.

5. Claudio Chiastra, Wei Wu, Benjamin Dickerhoff, Ali Aleiou, Hiromasa Otake, Francesco Migliavacca, John F. LaDisa, Jr. Computational replication of the patient-specific stenting procedure for coronary artery bifurcations: from OCT and CT imaging to structural and hemodynamics analyses. J Biomech. 2016 Jul

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26;49(11):2102-11. doi: 10.1016/j.jbiomech.2015.11.024. Special Issue of CFD in Medicine & Biology II

6. Laura Ellwein, David S. Marks, Raymond Q. Migrino, W. Dennis Foley, Sara Sherman, John F. LaDisa, Jr. Image-based quantification of 3-D morphology for bifurcations in the left coronary artery: application to stent design. Cathet. Catheter Cardiovasc Interv. 2016 Jun;87(7):1244-55 doi: 10.1002/ccd.26247

7. Hongfeng Wang, Dorothee Weihrauch, Judy R. Kersten, Jeffrey M. Toth, Anthony G. Passerini, Anita Rajamani, Sonja Schrepfer, John F. LaDisa, Jr. Alagebrium inhibits restenosis and restores shear stress via downstream vascular resistance in obese and diabetic rats. Am J Physiol Heart Circ Physiol. 2015 Oct;309(7):H1130-40.

8. John F. LaDisa, Jr., Serdar Bozdag, Jessica Olson, Ramani Ramchandran, Judy R. Kersten, Thomas J. Eddinger. Gene expression in experimental aortic coarctation and repair: candidate genes for therapeutic intervention? PLoS One. 2015 Jul 24;10(7):e0133356.

9. Margaret M Samyn, Ronak Dholakia, Hongfeng Wang, Jennifer Co-Vu, Ke Yan, Michael E. Widlansky, John F. LaDisa, Jr., Pippa Simpson, Ramin Alemzadeh. Cardiovascular magnetic resonance imaging-based computational fluid dynamics/fluid-structure interaction pilot study to detect early vascular changes in pediatric patients with type 1 diabetes. Pediatr Cardiol. 2015 Apr;36(4):851-61.

10. David J. Quam, Timothy J. Gundert, Laura M. Ellwein, Chris E. Larkee, Paul Hayden, Raymond Q. Migrino, Hiromasa Otake, John F. LaDisa, Jr. Immersive visualization for enhanced computational fluids dynamics analysis. J Biomech Eng. 2015 Mar 1;137(3). doi: 10.1115/1.4029017. [Epub ahead of print]

11. Sung Kwon, Jeffrey A. Feinstein, Ronak Dholakia, John F. LaDisa, Jr. Quantification of local hemodynamic alterations caused by virtual implantation of three commercially-available stents for the treatment of aortic coarctation. Pediatr Cardiol. 2014 Apr; 35(4):732-40. doi: 10.1007/s00246-013-0845-7

12. Timothy J. Gundert, Ronak J. Dholakia, Dennis McMahon, John F. LaDisa, Jr. Computational fluid dynamics evaluation of equivalency in hemodynamic alterations between Driver, Integrity and similar stents implanted into an idealized coronary artery. J Med Device. 2013 Feb;7(1):011004 doi:10.1115/1.4023413

13. Arjun Menon, Thomas J. Eddinger, Hongfeng Wang, David C. Wendell, Jeffrey M. Toth, John F. LaDisa, Jr. Altered hemodynamics, endothelial function and protein expression occur with aortic coarctation and persist following repair. Am J Physiol Heart Circ Physiol. 2012 Dec;303(11):H1304-18.

14. David C. Wendell, Margaret M. Samyn, Joseph R. Cava, Laura M. Ellwein, Mary M. Krolikowski, Kimberly L. Gandy, Andrew N. Pelech, Shawn C. Shadden, John F. LaDisa, Jr. Including aortic valve morphology in computational fluid dynamics simulations: initial findings and application to aortic coarctation. Med Eng Phys. 2013 Jun; 35(6):723-35.

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15. Timothy J. Gundert, Alison L. Marsden, Weiguang Yang, David S. Marks, John F. LaDisa, Jr. Identification of hemodynamically optimal coronary stent designs based on vessel diameter. IEEE Trans Biomed Eng. 2012 July; 59(7):1992-2002.

16. Jessica S. Coogan, Frandics P. Chan, John F. LaDisa, Jr., Charles A. Taylor, Frank L. Hanley, Jeffrey A. Feinstein. Computational fluid dynamic simulations for determination of ventricular workload in aortic arch obstructions. J Thorac Cardiovasc Surg. 2013 Feb; 145(2):489-495.e1

17. Timothy J. Gundert, Alison L. Marsden, Weiguang Yang, John F. LaDisa, Jr. Optimization of cardiovascular stent design using computational fluid dynamics. J Biomech Eng 2012 Jan;134(1):011002 doi:10.1115/1.4005542. 1 of 9 papers selected to the 2012 Editor's Choice list

18. Arjun Menon, David C. Wendell, Hongfeng Wang, Thomas J. Eddinger, Jeffrey M. Toth, Ronak J. Dholakia, Paul M. Larsen, Eric S. Jensen, John F. LaDisa, Jr. A novel coupled experimental and computational approach to quantify deleterious hemodynamics, vascular alterations, and mechanisms of long-term morbidity in response to aortic coarctation. J Pharmacol Toxicol Meth. 2012 Jan; 65(1):18-28.

19. John F. LaDisa, Jr, C. Alberto Figueroa, Irene E. Vignon-Clementel, Hyun Jin Kim, Nan Xiao, Laura M. Ellwein, Frandics P. Chan, Jeffrey A. Feinstein, Charles A. Taylor. Computational simulations for aortic coarctation: representative results from a sampling of patients. J. Biomech. Eng. 2011 Sep;133(9):091008. doi:10.1115/1.4004996. = authors contributed equally

20. John F. LaDisa, Jr., Ronak J. Dholakia, C. Alberto Figueroa, Irene E. Vignon-Clementel, Frandics P. Chan, Margaret M. Samyn, Joseph R. Cava, Charles A. Taylor, Jeffrey A. Feinstein. Computational simulations demonstrate altered wall shear stress in aortic coarctation patients previously treated by resection with end-to-end anastomosis. Congenit Heart Dis. 2011 Sep; 6(5): 432-43.

21. Laura M. Ellwein, Hiro Otake, Timothy J. Gundert, Bon-Kwon Koo, Toshiro Shinke, Yasuhiro Honda, Junya Shite, John F. LaDisa, Jr. Optical coherence tomography for patient-specific 3D artery reconstruction and evaluation of wall shear stress in a left circumflex coronary artery. Cardiovasc Eng Tech. 2011 Sept; 2(3): 212-7.

22. Timothy J. Gundert, Shawn C. Shadden, Andrew R. Williams, Bon-Kwon Koo, Jeffrey A. Feinstein, John F. LaDisa, Jr. A rapid and computationally inexpensive method for assessing patient-specific hemodynamic alterations introduced by commercially available and next-generation stents. Ann Biomed Eng. 2011 May; 39(5): 1423-37.

23. John F. LaDisa, Jr., Charles A. Taylor, Jeffrey A. Feinstein. Aortic coarctation: recent developments in experimental and computational methods to assess treatments for this simple condition. Prog Pediatr Cardiol 2010 Dec; 30(1): 45-9.

24. Raymond Q. Migrino, Mark R. Bowers, Leanne Harmann, Robert Prost, John F. LaDisa, Jr. Carotid plaque regression following 6-month statin therapy assessed by 3T MRI: comparison with ultrasound intima media thickness. J Cardiovasc Magn Reson. 2011 Aug 3;13(1):37.

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25. Andrew R. Williams, Bon-Kwon Koo, Timothy J. Gundert, Peter J. Fitzgerald, John F. LaDisa, Jr. Local hemodynamic changes caused by main branch stent implantation and subsequent side branch balloon angioplasty in a representative coronary bifurcation. J Appl Physiol. 2010 Aug; 109(2): 532-40.

26. James E. Moore Jr., Lucas H. Timmins, John F. LaDisa, Jr. Coronary artery bifurcation biomechanics and implications for interventional strategies. Catheter Cardiovasc Interv. 2010 Nov 15; 76(6):836-43.

27. John F. LaDisa, Jr., Mark R. Bowers, Leanne Harmann, Robert Prost, Anil Doppalapudi, Tayyab Mohyuddin, Osama Zaidat, Raymond Q. Migrino. Time-efficient patient-specific quantification of regional carotid artery fluid dynamics and spatial correlation with plaque burden following statin treatment. Medical Physics. 2010 Feb; 37(2): 784-92.

28. Hyun Jin Kim, Irene E. Vignon-Clementel, C. Alberto Figueroa, John F. LaDisa, Jr, Kenneth E. Jansen, Jeffrey A. Feinstein, Charles A. Taylor. On coupling a lumped parameter heart model and a three-dimensional finite element aorta model. Ann Biomed Eng. 2009 Nov; 37(11): 2153-69.

Submitted: 29. John F. LaDisa, Jr., Aoy Tomita-Mitchell, Karl Stamm, Kathleen Bazan, Donna K.

Mahnke, Mary Goetsch, Brandon J. Wegter, Jesse W. Gerringer, Kathryn Repp, Oleg Palygin, Mary M. Krolikowski, Thomas J. Eddinger, Abdel A. Alli, Michael E. Mitchell. Human genotyping and a novel experimental model reveal NPR-C as a possible contributor to morbidity in coarctation of the aorta. Submitted

30. Giuseppe Mazzone, Christopher Larkee, John F. LaDisa, Jr. A new approach to architecture history: an immersive reconstruction of Guarino Guarini’s Sainte-Anne-la-Royale in Paris. Submitted

Prior to accepting faculty position at Marquette University:

31. John F. LaDisa, Jr., Lars E. Olson, Douglas A. Hettrick, David C. Warltier, Judy R. Kersten, and Paul S. Pagel. Alterations in regional vascular geometry produced by theoretical stent implantation influence distributions of wall shear stress: analysis of a curved coronary artery using 3D computational fluid dynamics modeling. Biomed Eng Online. 2006 June 16; 5:40.

32. John F. LaDisa, Jr., Lars E. Olson, Douglas A. Hettrick, David C. Warltier, Judy R. Kersten, and Paul S. Pagel. Axial stent strut angle influences wall shear stress after stent implantation: analysis using 3D computational fluid dynamics models of stent foreshortening. Biomed Eng Online. 2005 Oct 26; 4(1):59.

33. John F. LaDisa, Jr., Lars E. Olson, Kristina M. Ropella, Robert C. Molthen, Steven T. Haworth, Judy R. Kersten, David C. Warltier, and Paul S. Pagel. Microfocal x-ray computed tomography post-processing operations for optimizing reconstruction volumes of stented arteries during 3D computational fluid dynamics modeling. Comput Methods Programs Biomed. 2005 Aug; 79(2):121-34.

34. John F. LaDisa, Jr., Lars E. Olson, Robert C. Molthen, Douglas A. Hettrick, Michael D. Hardel, Phillip F. Pratt, Judy R. Kersten, David C. Warltier, and Paul S. Pagel. Alterations in wall shear stress predict sites of neointimal hyperplasia after

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stent implantation in rabbit iliac arteries. Am J Physiol Heart Circ Physiol. 2005 May; 288(5):H2465-75.

35. John F. LaDisa, Jr., Lars E. Olson, Ismail Guler, Douglas A. Hettrick, Judy R. Kersten, David C. Warltier, and Paul S. Pagel. Circumferential vascular deformation after stent implantation alters wall shear stress evaluated using time-dependent 3D computational fluid dynamics models. J Appl Physiol. 2005; 98(3):947-57.

36. John F. LaDisa, Jr., Heidi T. Meier, Lars E. Olson, Judy R. Kersten, David C. Warltier and Paul S. Pagel. Antegrade iliac artery stent implantation for the temporal and spatial examination of stent-induced neointimal hyperplasia and alterations in regional fluid dynamics. J Pharmacol Toxicol Methods. 2005 Mar-Apr; 51(2):115-21.

37. John F. LaDisa Jr., John G. Krolikowski, Paul S. Pagel, David C. Warltier, and Judy R. Kersten. Cardioprotection by glucose-insulin-potassium: dependence on KATP channel opening and blood glucose concentration before ischemia. Am J Physiol Heart Circ Physiol. 2004 Aug; 287(2): H601-H607.

38. John F. LaDisa, Jr., Lars E. Olson, Ismail Guler, Douglas A. Hettrick, Said H. Audi, Judy R. Kersten, David C. Warltier, Paul S. Pagel. Stent design properties and deployment ratio influence indices of wall shear stress: a 3D computational fluid dynamics investigation within a normal artery. J Appl Physiol. 2004 July; 97(1):424-30.

39. Franz Kehl, John F. LaDisa Jr., Douglas A. Hettrick, Judy R. Kersten, David C. Warltier, Paul S. Pagel. Influence of isoflurane on left atrial function in dogs with pacing-induced cardiomyopathy: Evaluation with pressure-volume relationships. J of Cardiothorac and Vasc Anesth. 2003 Dec; 17(6):709-14.

40. Lynda M. Ludwig, Judy R. Kersten, Katsuya Tanaka, Weidong Gu, John F. LaDisa, Jr., David C. Warltier, Paul S. Pagel. Mechanisms of volatile anesthetic-induced myocardial protection. Curr Top in Pharmacol. 2003; 7(2): 195-207.

41. John F. LaDisa Jr., Ismail Guler, Lars E. Olson, Douglas A. Hettrick, Judy R. Kersten, David C. Warltier, Paul S. Pagel. Three-dimensional computational fluid dynamics modeling of alterations in coronary artery wall shear stress produced by stent implantation. Ann Biomed Eng. 2003 Aug; 31(8):972-980.

42. John F. LaDisa, Jr., Eric R. Gross, Dorothee Weihrauch, Douglas A. Hettrick, Lars E. Olson, Tobias Kress, Paul S. Pagel, David C. Warltier, and Judy R. Kersten. Reactive oxygen species modulate alterations in coronary wall shear stress and endothelial function during hyperglycemia. Am J Physiol Heart Circ Physiol. 2003 May; 284(5):H1552-H1559.

43. Franz Kehl, John G. Krolikowski, John F. LaDisa Jr., Judy R. Kersten, David C. Warltier, and Paul S. Pagel. Adenosine type 1 (A(1)) receptors mediate protection against myocardial infarction produced by chronic, intermittent ingestion of ethanol in dogs. Int J Cardiol. 2003 Apr; 88(2-3):175-82.

44. John F. LaDisa Jr., Douglas A. Hettrick, Lars E. Olson, Ismail Guler, Eric R. Gross, Tobias T. Kress, Judy R. Kersten, David C. Warltier, and Paul S. Pagel. Stent

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implantation alters coronary artery hemodynamics and wall shear stress during maximal vasodilation. J Appl Physiol. 2002 Dec; 93(6):1939-1946.

45. Katsuya Tanaka, Dorothee Weihrauch, Franz Kehl, Lynda M. Ludwig, John F. LaDisa Jr., Judy R. Kersten, Paul S. Pagel, and David C. Warltier. Mechanism of preconditioning by isoflurane in rabbits: a direct role for reactive oxygen species. Anesthesiology. 2002 Dec; 97(6):1485-1490.

46. Richard Rys, John F. LaDisa, Jr., John P. Tessmer, Judy R. Kersten, David C. Warltier, and Paul S. Pagel. An automated coronary artery occlusion device for stimulating collateral development in vivo. J Pharmacol Toxicol Methods. 2002; 48:111-18.

ABSTRACTS (students and trainees indicated in boldface)

Since accepting faculty position at Marquette University: 1. John T. Venn, Christopher Larkee, Guilherme JM Garcia, Vitaliy L Rayz, John F.

LaDisa, Jr. A workflow for viewing biomedical CFD results within virtual and augmented reality environments. Submitted to 8th World Congress of Biomechanics, Dublin, 7/8-7/12/2018.

2. Brandon J. Wegter, Abdel A. Alli, Jesse W. Gerringer, John F. LaDisa, Jr. Natriuretic peptide receptor C as a contributor to mechanically-induced morbidity in coarctation of the aorta. Submitted to 8th World Congress of Biomechanics, Dublin, 7/8-7/12/2018

3. Jesse W. Gerringer, John F. LaDisa, Jr. Mitigating differences across scales to translate a new treatment threshold back to the clinic. Submitted to 8th World Congress of Biomechanics, Dublin, 7/8-7/12/2018

4. Atefeh Razavi, Harkamaljot S. Kandail, John F. LaDisa Jr. Patient-specific drug elution simulations in stented coronary arteries using a combined experimental-numerical scheme", 13th World Congress on Computational Mechanics / 2nd Pan American Congress on Computational Mechanics, New York, July 22-27, 2018

5. Brandon Wegter, Thomas J. Eddinger, Aoy Tomita-Mitchell, Karl Stamm, Donna K. Mahnke, Mary Goetsch, Michael E. Mitchell, Ronald K. Woods, John F. LaDisa, Jr. Elucidating the mechanisms of irreversible vascular changes after treatment for aortic coarctation. Annual Meeting of the Biomedical Engineering Society, Minneapolis, October 5-8, 2016.

6. John Venn, Christopher Larkee, John F. LaDisa, Jr. Immersive visualization for comparative viewing of CFD results with associated multiscale data. Annual Meeting of the Biomedical Engineering Society, Minneapolis, October 5-8, 2016.

7. Ali A. Aleiou, Amirhossein Arzani, Shawn C. Shadden, Mehdi Maadooliat, Hiromasa Otake, John F. LaDisa, Jr. Slice-by-slice evaluation of wall shear stress in stented coronary arteries reconstructed using optical coherence and computed tomography: uncovering the stimuli for restenosis and resorption. Annual Meeting of the Biomedical Engineering Society, Minneapolis, October 5-8, 2016.

8. Brandon Wegter, Thomas J. Eddinger, Ronald K. Woods, John F. LaDisa, Jr. Characterizing the mechanical stimuli for a proposed new blood pressure gradient to

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guide treatment of aortic coarctation. 5th International Conference on Engineering Frontiers in Pediatric and Congenital Heart Disease, June 9 & 10, 2016 Orlando, Florida, USA. Received Best Poster Award

9. Chris Larkee, John F. LaDisa, Jr. An efficient approach to playback of stereoscopic videos using a wide field-of-view. Stereoscopic Displays and Applications, San Francisco, Feb 14-18, 2016. Awarded Best use of stereoscopic content

10. Francesco Migliavacca, Claudio Chiastra, Wei Wu, Ali Aleiou, Hiromasa Otake, John F. LaDisa, Jr. Patient-specific virtual stenting in coronary bifurcations: from medical images to fluid dynamics. Computational Fluid Dynamics in Medicine and Biology II, Albufeira, Portugal, 8/30-9/4/2015.

11. Eulogio Garcia, John F. LaDisa, Jr, Dustin Thompson. Novel core wire technology on a zotarolimus eluting stent provides improved acute performance, including deliverability and radiopacity. EuroPCR, Paris, France, 5/19-22/2015.

12. Claudio Chiastra, Wei Wu, Hiromasa Otake, Ali Aleiou, Gabriele Dubini, Francesco Migliavacca, John F. LaDisa, Jr. Virtual Patient-Specific Coronary Bifurcation Stenting: Comparison with Post-Operative Outcomes. BMES/FDA Frontiers in Medical Devices Conference, College Park, MD, 5/18-20/2015

13. Joshua K. Hughey, Hiromasa Otake, Ken-ichi Hirata, John F. LaDisa, Jr. Impact of stent platform on wall shear stress distributions after implantation: insights from computational fluid dynamics simulations using optical coherence tomography and coronary CT angiography. 7th World Congress of Biomechanics, Boston, 7/6-7/11/2014. Awarded 2nd place in the MS level poster competition

14. Joshua K. Hughey, Hiromasa Otake, Francesco Migliavacca, Mahdi Esmaily-Moghadam, Wei Wu, Claudio Chiastra, Nathan M. Wilson, Alison L. Marsden, John F. LaDisa, Jr. Towards optimizing mechanical stimuli around stents to reduce restenosis for challenging coronary artery lesions. 7th World Congress of Biomechanics, Boston, 7/6-7/11/2014.

15. Joshua K. Hughey, Michael Kamykowski, John F. LaDisa, Jr., Hiromasa Otake. Evaluation of wall shear stress in stented coronary arteries using optical coherence tomography and computational fluid dynamics. BMES Midwest Biomedical Engineering Career Conference, Chicago, IL, 4/19/13.

16. William M. Wang, David. J. Quam, Ronald K. Woods, John F. LaDisa, Jr. Toward the development of a stereoscopic visualization system with intuitive gesture-based control for biomedical and scientific datasets. BMES Midwest Biomedical Engineering Career Conference, Chicago, IL, 4/19/13.

17. Thomas A. Dienhart, Deepak Sharma, Robert W. Prost, John F. LaDisa, Jr. Initial analysis of local stent-induced blood flow alterations in a virtually-created arteriovenous fistula using computational fluid dynamics. BMES Midwest Biomedical Engineering Career Conference, Chicago, IL, 4/19/13.

18. Nathan M. Wilson, Ana K. Ortiz, Allison B. Johnson, Jeffrey A. Feinstein, John F. LaDisa, Jr., Alison L. Marsden. A public repository of image-based computational models and patient-specific blood flow simulation results. ASME Bioengineering Division, Summer Bioengineering Conference, Sunriver, OR, 6/26-29/13

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19. Laura M. Ellwein, John F. LaDisa, Jr., Stacy Leibham, Sheila Schindler-Ivens, Margaret M. Samyn. Quantification of thoracic aorta blood flow by magnetic resonance imaging during supine cycling exercise of increasing intensity. 2013 annual meeting of the Society for Cardiovascular Magnetic Resonance (SCMR). 1/31/13-2/3/13 in San Francisco.

20. DJ Quam, John F. LaDisa, Jr., Ronald K. Woods. Stereoscopic Visualization System with Intuitive Gesture-Based Control for Biomedical and Scientific Datasets. 2012 Engineering Frontiers conference. Stanford University and Lucile Packard Children's Hospital, 2012.

21. Laura M. Ellwein, Margaret M. Samyn, Michael Danduran, Sheila Schindler-Ivens, Stacy Leibham, John F. LaDisa, Jr. Translating near-infrared spectroscopy tissue oxygenation data for computational modeling of aortic and peripheral hemodynamics during exercise. Podium and poster presentation - 2012 Engineering Frontiers conference. Stanford University and Lucile Packard Children's Hospital, 2012.

22. Timothy J. Gundert, Alison L. Marsden, Weiguang Yang, John F. LaDisa, Jr. Identification of hemodynamically optimal stent configurations using computational fluid dynamics. FDA Computational Modeling for Cardiovascular Devices workshop in Rockville, MD, 2011.

23. DJ Quam, Laura M. Ellwein, Raymond Q. Migrino, John F. LaDisa, Jr. Mobile virtual reality system for cardiovascular CFD analysis. Annual Meeting of the Biomedical Engineering Society, Hartford, 2011.

24. Hongfeng Wang, Laura M. Ellwein, Judy R. Kersten, John F. LaDisa, Jr. Vascular changes in type 2 diabetes mellitus: application to restenosis after stenting. Accepted for poster - Annual Meeting of the Biomedical Engineering Society, Austin, 2010.

25. Laura M. Ellwein, Hiromasa Otake, Bon-Kwon Koo, Toshiro Shinke, Yasuhiro Honda, Junya Shite, John F. LaDisa, Jr. Characterization of coronary artery pathologies and shear stress by optical coherence tomography. Accepted for podium presentation - Annual Meeting of the Biomedical Engineering Society, Austin, 2010.

26. Timothy J. Gundert, John F. LaDisa, Jr. Evaluation of cerebral aneurysm stent performance in a subject-specific computational model. Accepted for poster - ASME Bioengineering Division, Summer Bioengineering Conference, Naples, 2010.

27. Sara Nomeland, Raymond Q. Migrino, David S. Marks, John F. LaDisa, Jr. Image-based quantification of 3-D morphology for bifurcations in the left coronary artery: application to stent design. Podium presentation - FDA Computational Modeling for Cardiovascular Devices workshop in Rockville, MD, 2010.

28. Andrew R. Williams, Jonathan A. Freeman, Raymond Q. Migrino, Bon-Kwon Koo, David S. Marks, W. Dennis Foley, John F. LaDisa, Jr. Computational simulations from CT angiography demonstrate altered hemodynamics in realistic stented coronary artery bifurcations. Annual Meeting of the Biomedical Engineering Society, Pittsburgh, 2009.

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29. David C. Wendell, Joseph Cava, Margaret Samyn, John F. LaDisa, Jr. Influence of aortic valve morphology on arch hemodynamics after successful aortic coarctation repair. Annual Meeting of the Biomedical Engineering Society, Pittsburgh, 2009.

30. Timothy J. Gundert, Andrew R. Williams, John F. LaDisa, Jr. Rapid and computationally inexpensive quantification of hemodynamic alterations introduced by commercially-available and next-generation stents. FDA Computational Modeling for Cardiovascular Devices workshop in Rockville, MD, 2009.

31. Timothy J. Gundert, Paul Hayden, Raymond Q. Migrino, John F. LaDisa, Jr. Visualization of CFD results in a virtual reality environment. ASME Bioengineering Division, Summer Bioengineering Conference, Lake Tahoe, 2009.

32. John F. LaDisa, Jr., Joseph Cava, Ronak Dholakia, David Wendell, Mary Krolikowski, Margaret Samyn. Computational simulations from cardiac magnetic resonance imaging reveal altered hemodynamics in coarctation patients previously treated by patch aortoplasty Society of Cardiovascular Magnetic Resonance (SCMR) Annual Scientific Sessions. Orlando, 2009.

33. John F. LaDisa, Jr., Robert Prost, Leanne Harmann, Anil Doppalapudi, Tayyab Mohyuddin, Megan Bright, Raymond Q. Migrino. Relationship between regional wall shear stress and carotid plaque composition using 3T MRI and patient-specific computational fluid dynamics. Society of Cardiovascular Magnetic Resonance (SCMR) Annual Scientific Sessions. Orlando, 2009.

34. Ronak J. Dholakia, Paul M. Larsen, David C. Wendell and John F. LaDisa, Jr. An experimental and computational study of hemodynamics and arterial structure in aortic coarctation. Annual Meeting of the Biomedical Engineering Society, St. Louis, 2008.

35. David Wendell, Paul S. Pagel and John F. LaDisa, Jr. Assessment of left ventricular function after treatment of aortic coarctation in an animal model. Annual Meeting of the Biomedical Engineering Society, St. Louis, 2008.

36. Nathan M. Wilson, Raymond Q. Migrino, Leanne Harmann, Robert W. Prost, and John F. LaDisa, Jr. Modeling and realistic simulation of the carotid artery bifurcation using 3-D image segmentation implemented in a commercial software package for hemodynamic simulation (cvSimTM). ASME - Bioengineering Division, Summer Bioengineering Conference, Marco Island, 2008.

37. John F. LaDisa Jr., Robert Prost, Leanne Harmann, Tayyab Mohyuddin, Osama Zaidat, Jason Jurva, Anil Doppalapudi, Megan Bright and Raymond Q. Migrino. Patient-specific computational simulations of carotid artery hemodynamics complement clinical imaging data and correlate with plaque morphology after statin treatment. 5th International Caltech Biofluids Symposium and Workshop, Pasadena CA, March 28-30, 2008.

38. John F. LaDisa, Jr., Robert Prost, Leanne Harmann, Tayyab Mohyuddin, Osama Zaidat, Jason Jurva, Mahazarin Kaikobad, Megan Bright and Raymond Q. Migrino. Regional differences in carotid plaque morphology and shear stress using combined 3T MRI, ultrasound and patient-specific computational fluid dynamics

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and the effects of short-term statin treatment. SCAI Annual Scientific Sessions/ACC i2 Summit, Chicago, 2008.

39. John F. LaDisa, Jr., C. Alberto Figueroa, Irene E. Vignon-Clementel, Frandics P. Chan, Charles A. Taylor, Jeffrey A. Feinstein, Computational simulations demonstrate altered biomechanics in post-operative aortic coarctation patients. Annual Meeting of the American College of Cardiology, Chicago, 2008.

40. Lars E. Olson, John F. LaDisa, Jr., A model of shear-dependent neointimal growth of stented vessels. Annals of Biomedical Engineering, Biomedical Engineering Society, Los Angeles, 2007.

41. John F. LaDisa, Jr., C. Alberto Figueroa, Irene E. Vignon-Clementel, Frandics P. Chan, Jeffrey A. Feinstein, Charles A. Taylor. Use of CFD for the replication of clinical blood flow and pressure measurements and characterization of hemodynamics in the normal ascending and thoracic aorta. ASME Bioengineering Division, Summer Bioengineering Conference, Keystone, 2007.

42. Andrea S. Les, Christopher P. Cheng, Mary T. Draney Blomme, C. Alberto Figueroa, John F. LaDisa, Jinha M. Park, Robert J. Herfkens, Ronald L. Dalman, Charles A. Taylor. Hemodynamics in abdominal aortic aneurysms during rest and simulated exercise. ASME - Bioengineering Division, Summer Bioengineering Conference, Keystone, 2007.

Prior to accepting faculty position at Marquette University: 43. John F. LaDisa, C. Alberto Figueroa, Irene E. Vignon-Clementel, Frandics P.

Chan, Jeffrey A. Feinstein, Charles A. Taylor. CFD estimation of hemodynamic alterations and indices of morbidity in aortic coarctation patients during moderate exercise. Invited Paper - 5th World Congress of Biomechanics, Munich, Aug 2006.

44. John F. LaDisa, Lars E. Olson, David C. Warltier, Paul S. Pagel. Computational fluid dynamics estimates of alterations in wall shear stress influencing neointimal hyperplasia after stent implantation. Invited Paper - 5th World Congress of Biomechanics, Munich, August 2006.

45. John F. LaDisa, Charles A. Taylor, Jeffrey A. Feinstein. Stent-induced alterations in compliance and hemodynamics in the aorta and head and neck arteries of patients with aortic coarctation. Society for Cardiac Angiography and Interventions, Chicago, 2006.

46. Alberto Figueroa, John F. LaDisa, Irene E. Vignon-Clementel, Kenneth E. Jansen, Thomas J.R. Hughes, Jeffrey A. Feinstein, Charles A. Taylor. A coupled-momentum method for fluid-structure interaction: application to aortic coarctation. 2nd International Conference on Computational Bioengineering, Lisbon, Portugal, September 14-16, 2005.

47. Irene E. Vignon-Clementel, C. Alberto Figueroa, John F. LaDisa, Jeffrey A. Feinstein, Kenneth E. Jansen, Charles A. Taylor. Impedance outflow boundary conditions for three-dimensional patient specific modeling of blood flow. ASME Bioengineering Division, Summer Bioengineering Conference, Vail, 2005.

48. John F. LaDisa, David C. Warltier, Lars E. Olson, Steve T. Haworth, Robert C. Molthen, Douglas A. Hettrick, Judy R. Kersten, Paul S. Pagel. Distributions of wall

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shear stress influence neointimal hyperplasia after stent implantation in vivo. Annals of Biomedical Engineering, Biomedical Engineering Society, Philadelphia, 2004.

49. John F. LaDisa, Lars E. Olson, Judy R. Kersten, David C. Warltier, Paul S. Pagel. Wall shear stress varies with stent properties and correlates with sites of neointimal hyperplasia. Annals of Biomedical Engineering, Biomedical Engineering Society, Nashville, 2003.

50. Franz Kehl, John F. LaDisa, Judy R. Kersten, David C. Warltier, Paul S. Pagel. Isoflurane adversely alters active and passive left atrial function and impairs left atrial-left ventricular coupling in dogs with pacing-induced cardiomyopathy as evaluated using pressure-volume relations. American Society of Anesthesiologists, San Francisco, 2003.

51. John F. LaDisa, David C. Warltier, Ismail Guler, Judy R. Kersten, Paul S. Pagel. Stent geometry and deployment ratio influence distributions of wall shear stress: three-dimensional numerical simulations exploiting properties of an implanted stent. ASME Bioengineering Division, Summer Bioengineering Conference, Key Biscayne, 2003.

52. John F. LaDisa, David C. Warltier, Lars E. Olson, Judy R. Kersten, Paul S. Pagel. Shear-modulated neointimal hyperplasia after stent implantation. FASEB Journal - Experimental Biology, San Diego, 2003.

53. Weidong Gu, John F. LaDisa, Paul S. Pagel, David C. Warltier, Judy R. Kersten. Simvastatin restores the cardioprotective effect of ischemic preconditioning in the presence of hyperglycemia through a NO-mediated mechanism. American Society of Anesthesiologists, Orlando, 2002.

54. John F. LaDisa, John G. Krolikowski, Lynda M. Ludwig, Paul S. Pagel, David C. Warltier, Judy R. Kersten. Diabetes, Hyperglycemia, GIK and Cardioprotection: Do KATP Channels Play a Role? Journal of the American College of Cardiology, American College of Cardiology, Chicago, 2002.

55. John F. LaDisa, Lars E. Olson, Ismail Guler, Eric R. Gross, Douglas A. Hettrick, Judy R. Kersten, David C. Warltier, Paul S. Pagel. Coronary stent implantation alters wall shear stress during maximal vasodilation. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. v2 2002. p1228-1229. Houston, 2002.

56. John F. LaDisa, Lars E. Olson, Douglas A. Hettrick, Ismail Guler, Fernando DiCaprio, Paul S. Pagel, Judy R. Kersten, David C. Warltier. CFD modeling of hemodynamic changes caused by coronary stenting in vivo. Annals of Biomedical Engineering, Biomedical Engineering Society, Raleigh/Durham, 2001.

57. John F. LaDisa, Lars E. Olson, Fernando DiCaprio, Ismail Guler, David C. Warltier. In vivo measurement and fluid dynamics modeling of hemodynamic changes produced by coronary stenting. FASEB Journal - Experimental Biology, Orlando, 2001.

ladisa, curriculum vitae - marquette university · curriculum vitae present positions: associate...

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