lactoclear wet wipes

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CELL BIOTECH EUROPE A/S | www.duolac.com | [email protected] Retail product description Product: LactoClear™ wet wipes 4,0g - Natural Acne Therapy

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Finished private label product packed in single dose wet wipes with tonic, wipes are in carton box. Contains the active ingredient Lactopad(tm)

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Page 1: LactoClear wet wipes

CELL BIOTECH EUROPE A/S | www.duolac.com | [email protected]

Retail product description Product: LactoClear™ wet wipes 4,0g - Natural Acne Therapy

Page 2: LactoClear wet wipes

CELL BIOTECH EUROPE A/S | www.duolac.com | [email protected]

Retail product description Product: LactoClear™ wet wipes 4g

20-09-2010/jg

Claims: Natural Acne Therapy, Natural for Acne,

Sold as: Private label cosmetic. With Lactopad brand name on the package

Packing: MOQ: 250.000 single wet wipes. Sachet 70x100 mm, wipe 170x180mm, 4g skin tonic on wet wipe, 14 wipes per carton box. 4 colour print on carton box.

Item / case number:

Item number: 96525 Formulation ID: ST 2402

Approvals/ certificates

Lactopad™ active component is manufactured under GMP conditions at Cell Biotech Co. Ltd. Korea. The Lactopad private label products are manufactured in Denmark by ABC.

Usage: Locally on unclear, irritated and erythematus skin and individual spots. Apply layer on problematic area in the morning and evening. In the beginning the skin can blish and feel itchy and tight.

Active content:

Bacteriocin: 4,0% Lactopad CBT-SL5 is one of the bacteriocins derived from Enterococcus faecalis SL5.

Ingredients:

Aqua, Glycerin, PEG-7 Glyceryl Cocoate, Maltodextrin, Enterococcus Faecalis Ferment, Sodium PCA, PEG-40 Hydrogenated Castor Oil, Niacinamide,

Phenoxyethanol, Benzoic Acid, Dehydroacetic Acid, Ehylhexylglycerin, Sodium Hydroxide

General information:

Use as symptomatic treatment or prevention of acne in adults, and children. Lactopad is a dried form of cell-free supernatant of a probiotic culture, the lactic

acid bacterium Enterococcus faecalis SL5, with an antibacterial activity against Propionibacterium acnes, a key causative agent of acne. Lactopad has a selective property, that is, it kills only target microbes selectively. Mechanism: Lactopad has simple primary structure that is composed of polypeptide chain. Hydrophobic aminoterminal end of the peptides enter the cell membrane and

makes a hole, and it kill the target microbes by changing the membrane potential. Please refer to clinical study:

1. Antimicrobial Activity of Enterocins from Enterococcus faecalis SL-5 against Propionibacterium acnes, the Causative Agent in Acne Vulgaris, and its Therapeutic Effect (ID 6A)

2. CBT-SL5, a Bacteriocin from Enterococcus faecalis, Suppresses the

Expression of Interleukin-8 Induced by Propionibacterium acnes in Cultured Human Keratinocytes (ID 6B)

Available documents:

01 Lactopad ™ specification and MSDS and all raw material specifications 02 CTFA registration, ISO 9001:2000 and ISO 14001. EUR1 cert

03 Challenge test (June 2010) 04 Production documents (Production flow diagram etc) 05 Product formulation 06 Packing documents