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24/09/2019 1 Frédéric DUTHEIL Mardi 24 septembre 2019 Assistance Publique Hôpitaux de Marseille Santé Travail Environnement, CHU Clermont-Ferrand LaPSCo UMR CNRS 6024 « Stress physiologique et psychosocial » La sédentarité au travail : un risque professionnel à part entière Key points Sedentary behavior kills We have sedentary behavior at work Sedentary behavior is an occupational risk Key points Sedentary behavior kills We have sedentary behavior at work Sedentary behavior is an occupational risk Background Physical activity Sedentary behavior Physical activity - +++ -

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Page 1: La sédentarité au travail : un risque professionnel à part ... · WittyFit Research 8. Connected objects 10. A powerful epidemiological database 9. Anonymous. 24/09/2019 22 Key

24/09/2019

1

Frédéric DUTHEIL

Mardi 24 septembre 2019Assistance Publique

Hôpitaux de Marseille

Santé Travail Environnement, CHU Clermont-Ferrand

LaPSCo UMR CNRS 6024 « Stress physiologique et psychosocial »

La sédentarité au travail : un risque professionnel

à part entière

Key points

•Sedentary behavior kills

•We have sedentary behavior at work

Sedentary behavior is an occupational risk

Key points

•Sedentary behavior kills

•We have sedentary behavior at work

Sedentary behavior is an occupational risk

Background

• Physical activity

• Sedentary behavior

Physical

activity

--+++-

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Mortality

reduction

Physical

activity

--+++-

Mortality

reduction

Physical

activity

--+++-

Mortality

reduction

Physical

activity

--+++-

14%

-

--+++ -

Physical

activity

-

Same

quantity

of PA

-+++ -

Physical

activity

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3

-+++ -

Physical

activity

Low

PA

-+++ -

Low

PA

High

PA

Physical

activity

-+++ -

Mortality Low

PA

High

PA

Physical

activity

-

Physical

activity+++ -

Mortality Low

PA

High

PA

-

Mortality

-

Mortality

Time

spent

sitting

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-

Mortality

Time

spent

sitting

sedentary

-

Mortality

Time

spent

sitting

sedentary

-

Mortality

Time

spent

sitting

sedentary

-

Mortality

Time

spent

sitting

sedentary

-

Mortality

Time

spent

sitting

sedentary

-

Mortality

Time

spent

sitting

Low PA

Low

sitting

High PA

High

sitting

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5

- -

-

At work?Observational studies

• Physical activity

• Sedentary behavior

At work?

Observational studies

• Physical activity

• Sedentary behavior

At work?

Epidemiology

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6

***

1960

30 h/

week

Sedentary behaviors increased

from 30 hours per week in 1960

to 42 hours par week in 2012

42 h/week

1960 2012

30 h/

week

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7

Observational studies

• Physical activity

• Sedentary behavior

At work?Observational studies

• Physical activity

• Sedentary behavior

At work?

Health

outcomes

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8

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Observational studies

• Physical activity

• Sedentary behavior

At work?

Health

outcomes

Observational studies

• Physical activity

• Sedentary behavior

At work?

Health

outcomes

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10

Interventional studies

• Physical activity

• Sedentary behavior

Health

outcomes

At work?Interventional studies

• Physical activity

• Sedentary behavior

Health

outcomes

At work?

Interventional studies

• Physical activity

• Sedentary behavior

Health

outcomes

≈ LeisureInterventional studies

• Physical activity

• Sedentary behavior

Health

outcomes

≈ Leisure

• MetS individuals randomized in 3 groups of

combined PA (endurance + résistance) with

differents intensities:

ReResistance-intense

endurance-moderate

rEresistance-moderate

Endurance-intense

reresistance-moderate

endurance-moderate

Randomization3 groups

International Journal of Cardiology

Different modalities of exercise to reduce visceral fat mass and

cardiovascular risk in metabolic syndrome: the RESOLVE*

randomized trial

-25

-20

-15

-10

-5

0

D0 D20 M3 M6 M12

% of loss Visceral fat loss

rE

re

Re

*****:p<.001, ***:p<.001, **:p<.01, *:p<.05

Re and rE vs. re.

††††:p<.0001 Re vs rE.

Combined training with

high intensity in

resistance induce faster

results

The 2 groups with high

intensity training had the

best visceral fat loss

International Journal of Cardiology

Different modalities of exercise to reduce visceral fat mass and

cardiovascular risk in metabolic syndrome: the RESOLVE*

randomized trial

****††††

****

******

**

*

*

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11

Interventional studies

• Physical activity

• Sedentary behavior

Health

outcomes

≈ LeisureInterventional studies

• Physical activity

• Sedentary behavior

Health

outcomes

Only on sedentary behaviors ?

Interventional studies

• Physical activity

• Sedentary behavior

Health

outcomes

Only on sedentary behaviors ?

Laboratory

Sitting 8

hours

Randomi-

zation

controlIntervention

Sitting 8

hours

2016

Sitting 8

hours

Randomi-

zation

controlIntervention

Sitting 8

hours+ 5 min standing

/30 min

2016 2016

controls

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12

2016

5 min

standing

/30 min

controls

Blood glucose and blood insulin

of 1/3 when standing 5 min/30 min

Interventional studies

• Physical activity

• Sedentary behavior

Health

outcomes

Interventional studies

• Physical activity

• Sedentary behavior

At work?

Health

outcomes

Interventional studies

• Physical activity

• Sedentary behavior

At work?

Health

outcomes

Only on sedentary behaviors ?

Interventional studies

• Physical activity

• Sedentary behavior

At work?

Health

outcomes

Only on sedentary behaviors ? Randomi-

zation

controlIntervention 6 months

at work:

Counseling

Nutrition

Physical activity

Stop smoking

Health education

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Randomi-

zation

controlIntervention 6 months

at work:

Counseling

Nutrition

Physical activity

Stop smoking

Health education

Well-being

Body

composition

CV Risk:- Blood lipids

- Blood pressure

One-year change in total medical cost

Salud Pública Mex 2012, 54:20-27 Salud Pública Mex 2012, 54:20-27

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Salud Pública Mex 2012, 54:20-27 Salud Pública Mex 2012, 54:20-27

Interventional studies

• Physical activity

• Sedentary behavior

At work?

Health

outcomes

Interventional studies

• Physical activity

• Sedentary behavior

At work?

Health

outcomes

the Stand Up Victoria cluster randomized trial

BMC Public Health.

Dunstan DW, Wiesner G, Eakin EG, Neuhaus M, Owen N, LaMontagne AD, Moodie

M, Winkler EA, Fjeldsoe BS, Lawler S, Healy GN.

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What kills ?

Sedentary

at workPoor

nutrition

habits

Stress

Working

conditionsGoldstone al 2004

The INTERHEART study

Rosengreen et al 2004

What kills ?

The Greek EPIC study

Trichopoulou et al 2009

Sendetary

at workPoor

nutrition

habits

Stress

Working

conditions

Chandola Eur. Heart J. 2008

Chikani Rural Health. 2005

Collins Am. J. Ind. Med. 2005

de Jonge Soc. Sci. Med. 2000

What kills ?

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16

Sendetary

at workPoor

nutrition

habits

Stress

Working

conditions

1. Globality

Novel

Well-being regarding 3 main categories:

- “Physically”

- “Mentally”

- “At Work”

Nutrition

Activity

Sleep

Musculo-skelettal

Stress

Mood Job strain

Latitude decision

Work organization, tasks

Social support

Recognition

1. Globality

Novel

2. How to interact ?

1. Globality

Novel1. Globality

Novel

2. How to interact ?

1. Globality

Novel

2. How to interact ?

1. Globality

Novel

2. How to interact ?

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1. Globality

Novel

2. How to interact ?

1. Globality

Novel

2. How to interact ?

1. Globality

Novel

2. Digital world

3. Personalized feedback

1. Globality

Novel

2. Digital world

3. Personalized feedback

Health

Check Report« e-learning »« Did you know ? »

1. Globality

Novel

2. Digital world

3. Personalized feedback

Health

Check Report« e-learning »« Did you know ? »

You eat 15 grams of salt per day.

An excess of salt increases blood pressure

1. Globality

Novel

2. Digital world

3. Personalized feedback

4. Up-to-date scientific knowledge (evidence

based medicine)

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1. Globality

Novel

2. Digital world

3. Personalized feedback

4. Up-to-date EBM

5. A feedback for managers

1. Globality

Novel

2. Digital world

3. Personalized feedback

4. Up-to-date EBM

5. A feedback for managers

6. Collaboration with Occupational Medicine

1. Globality

Novel

2. Digital world

3. Personalized feedback

4. Up-to-date EBM

5. A feedback for managers

6. Collaboration with Occupational Medicine

7. WittyFit… behavior data

1. Globality

Novel

2. Digital world

3. Personalized feedback

4. Up-to-date EBM

5. A feedback for managers

6. Collaboration with Occupational Medicine

7. WittyFit… behavior data

WittyFit Research medical data

1. Globality

Novel

2. Digital world

3. Personalized feedback

4. Up-to-date EBM

5. A feedback for managers

6. Collaboration with Occupational Medicine

7. WittyFit Research

8. Connected objects 8. Connected objects

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8. Connected objects 8. Connected objects

8. Connected objects 8. Connected objects

8. Connected objects

1. Globality

Novel

2. Digital world

3. Personalized feedback

4. Up-to-date EBM

5. A feedback for managers

6. Collaboration with Occupational Medicine

7. WittyFit Research

8. Connected objects

9. Anonymous

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Factories WittyFitn° HR

9. Anonymous

Factories WittyFitn° HR + random

9. Anonymous

Factories WittyFitn° HR + random

WittyFit

Research9. Anonymous

Factories WittyFitn° HR + random

WittyFit

Research

Factories WittyFitn° HR + random

WittyFit

Research

Factories WittyFitn° HR + random

WittyFit

Research

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21

Factories WittyFitn° HR + random

Retirement

Another company

Death

WittyFit

Research

Factories WittyFitn° HR + random

Retirement

Another company

Death

WittyFit

Research

Death Death

The main outcome:

1. Globality

Novel

2. Digital world

3. Personalized feedback

4. Up-to-date EBM

5. A feedback for managers

6. Collaboration with Occupational Medicine

7. WittyFit Research

8. Connected objects

9. Anonymous

1. Globality

Novel

2. Digital world

3. Personalized feedback

4. Up-to-date EBM

5. A feedback for managers

6. Collaboration with Occupational Medicine

7. WittyFit Research

8. Connected objects

10. A powerful epidemiological database

9. Anonymous

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22

Key points

•Sedentary behavior kills

•We have sedentary behavior at work

Sedentary behavior is an occupational risk

Key points

•Sedentary behavior kills

•We have sedentary behavior at work

Sedentary behavior is an occupational risk

Key points

•Sedentary behavior kills

•We have sedentary behavior at work

Sedentary behavior is an occupational risk

A massive area for future research

Frédéric DUTHEIL

Mardi 24 septembre 2019Assistance Publique

Hôpitaux de Marseille

Santé Travail Environnement, CHU Clermont-Ferrand

LaPSCo UMR CNRS 6024 « Stress physiologique et psychosocial »

La sédentarité au travail : un risque professionnel

à part entière