l2 structure and function of the nervous system

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    DSP Note-taker Needed

    $25 per unit (of the class)(this will be prorated based on the number

    of weeks for which they are hired)

    Questions: Please contact WandaThomas:

    Phone: 893-2668

    Email: [email protected]

    Please apply onlineat http://dsp.sa.ucsb.edu/services

    mailto:[email protected]://dsp.sa.ucsb.edu/serviceshttp://dsp.sa.ucsb.edu/servicesmailto:[email protected]:[email protected]:[email protected]
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    Neuronal Signaling: An Overview

    3. Receptors in the dendrite of the postsynaptic

    neuron receivethe neurotransmitters,

    depolarizing the membrane (cell wall).

    4. If the depolarization is strong

    enough, then it spreads down the

    dendrite and across the cell body

    integratingwith signals fromother dendrites at the axon

    hillock.

    2. The presynaptic neuron

    communicates to the

    postsyaptic neuron by releasing

    neurotransmitters across thesynapse.

    5. If the depolarization reaches

    a critical threshold at the axon

    hillock, then an action potential

    is conducteddown the axon.

    1. A presynaptic and postsynaptic neuron at rest.

    6. Once the action potential reaches the axon

    terminal, it releases neurotransmitters into the

    synapse transmittinga signal to other neurons.

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    Four factors establish the resting membrane potential.

    1) Concentration gradients

    2) Electrostatic pressure

    The Resting Membrane Potential of a Neuron

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    3) Permeability of the membrane to ions

    Four factors establish the resting membrane potential.

    The Resting Membrane Potential of a Neuron

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    4)Active ion transport (Na+/K+pump)

    The Resting Membrane Potential of a Neuron

    Four factors establish the resting membrane potential.

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    At rest:

    . . . Na+want to enter the neuron.

    . . . K

    +

    want to leave the neuron.

    . . . Cl-want to remain in equilibrium.

    The Resting Membrane Potential of a Neuron

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    Inhibitory postsynaptic potentials or IPSPs:

    Excitatory postsynaptic potentials or EPSPs:

    Polarizing the membrane of a neuron

    The Flow of Electrically Charged Ions

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    The Starting Site of an Action Potential

    Axon Hillock(Initial Segment)

    The Ionic Basis of the Action Potential

    The Flow of Electrically Charged Ions

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    Action potential: a massivemomentary (~1 msec) reversal of the

    membrane potential (from -70 mV to+50 mV)

    The Ionic Basis of the Action Potential

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    Cells Other Than Neurons (Glial Cells)

    Astrocytes:

    Microglial cells:

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    Oligodendrocytes

    Schwann cells

    Myelin

    Cells Other Than Neurons (Glial Cells)

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    Dorsal

    (superior)

    Ventral

    (inferior)

    Rostral(anterior)

    Caudal

    (posterior)

    lateralsurface

    medial

    surfacesulcus

    gyrus

    Some Neuroanatomy

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    Hindbrain

    Midbrain

    Forebrain

    Some Neuroanatomy

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    Hindbrain

    Cerebellum

    Brain Stem

    Some Neuroanatomy

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    Midbrain

    Reticular Formation

    Substantia nigra &ventral tegmental

    Some Neuroanatomy

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    Forebrain

    Cerebral CortexCorpus Callosum

    Thalamus

    Hypothalamus

    Some Neuroanatomy

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    Central sulcus

    Precentral gyrus

    Postcentral gyrus

    motor cortex

    somatosensory cortex

    Some Neuroanatomy

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    Central sulcus

    Postcentral gyrus

    Precentral gyrusmotor cortex

    somatosensory cortex

    Some Neuroanatomy

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    Frontal Lobe

    Temporal Lobe

    Parietal Lobe

    Occipital Lobe