See you in Krakow!www.europeanmeeting.org

Novel dosage forms,

innovative technologies

Krakow, Poland 3 to 4 April 2017Topics• Frombenchtobedside–frominnovativetechnologiestoclinicalsuccess• Justmarried:SMARTdevicesandSMARTdrugs• Enablingtechnologiesforpoorlybioavailabledrugs• Noveldeliverystrategiesfornon-Lipinskimolecules• Novelstrategiestoovercomephysiologicalbarriers

JAGIELLONIAN UNIVERSITYMEDICAL COLLEGE

HONORARY PATRONAGE

2nd European Conference on Pharmaceutics:

Novel Dosage Forms, Innovative Technologies

Krakow, Poland, 3 to 4 April 2017

DearColleague,

Followingthegreatsuccessof the1stEuropeanConferenceonPharmaceutics:DrugDelivery,whichwasheld inReims(France,in2015),itisourgreatpleasuretoannouncethesecondcongressofthisnewseriesofinternationalmeetings,whichwillbeheldinKrakow,Poland,on3to4April2017.ItwillbededicatedtoNovelDosageFormsandInnovativeTechnologies.

TheEuropeanConferencesonPharmaceuticsareheldeverytwoyears(inMarch/Apriloftheunevenyears).Theyare jointlyorganizedby theA.D.R.I.T.E.L.F. (“AssociazioneDocentiRicercatori ItalianidiTecnologieeLegislazioneFarmaceutiche”),APGI(“InternationalSocietyofDrugDeliverySciencesandTechnology“)andAPV(“InternationalAssociationforPharmaceuticalTechnology“).

Theaimistohelpbridgingthegapbetweenfundamentalacademicresearchandindustrialapplications,offeringtheopportunitytoinitiatefruitfulexchangeandcooperationbetweenuniversityandindustry.

TheConferencewillbeaperfectoccasionforyoungaswellasforestablishedscientistsfromacademiaandindustryfromallovertheworldtopresenttheirwork,network,discussnewestscientificfindingsandtosharetheirexperi-encewithcolleaguesonabroadrangeoftopicsrelatedtoNovelDosageFormsandInnovativeTechnologies.

World-wideleadingexpertsinthefieldwillgiveplenarylecturesandinvitedtalksonhottopics.Theywillgiveover-viewsonthecurrentstateoftheartintherespectivedomainsandoutlooksonfutureperspectives.

SpecialHotTopicsinKrakowwillinclude:• Frombenchtobedside–fromtechnologiestoclinicalsuccess• Justmarried:SMARTdevicesandSMARTdrugs• Enablingtechnologiesforpoorlybioavailabledrugs• Noveldeliverystrategiesfornon-Lipinskimolecules• Novelstrategiestoovercomephysiologicalbarriers

Inaddition,latestresearchfindingswillbepresentedintheformofshorttalks,selectedfromsubmittedabstracts.Furthermore,posterpresentationswillgivetheopportunitytogetanupdateonthemostrecentresearchinPhar-maceuticsandtopersonallyexchangewiththeauthors.

AnindustrialexhibitionwillaccompanytheConferenceandallowlearningaboutthelatesttrendsandnewestprod-uctsintheareaofpharmaceuticalingredients,developing&processingequipment,analyticaltechnologies,medici-nalproducts,medicaldevices,contractmanufacturingandmanyotherfields.

Allcoffeeandlunchbreaksaswellasthewelcomereceptionwillbeincludedintheregistrationfeesandbeheldintheindustrialexhibitionandposterpresentationareainordertofacilitatediscussionsbetweenparticipants,exhibi-torsandpresenters.

Krakowisworld-widefamousforitshistoricaloldtown,alongwiththeWawelCastleandthecity’sKazimierzdistrict.ItislocatedonthebanksoftheVistulaRiver,andwasforcenturiesthecapitalofPoland.KrakowhastraditionallybeenoneoftheleadingcentersofPolishacademic,culturalandartisticlife.Youcaneasilyreachthecitybycar,trainorplane(internationalairport).

Wearelookingforwardtoseeingyouatthe2ndEuropeanConferenceonPharmaceuticsinKrakowin2017!

Prof.AnnaMariaFadda Prof.JürgenSiepmann Prof.JörgBreitkreutzPresidentA.D.R.I.T.E.L.F. PresidentAPGI PresidentAPV

Monday, 3 April 2017

Plenary lecture09:15- From bench to bedside – from10:15 technologies to clinical success DrMarcoGentile,Dompe,Italy

10:15 - 10:45 Coffee/Exhibition/Posters

Invited talks:SMART drugs and SMART devices10:45- Macromolecular candidates for 11:25 novel drugs and delivery systems ProfMariaNowakowska,Jagiellonian University,Poland11:25- Novel strategies for targeted12:05 drug delivery ProfDanPeer,TelAvivUniversity,Israel12:05- Combination products for12:45 inhalation vs. injection DrMarcRohrschneider,Boehringer Ingelheim,Germany

Short talks:Preformulation and Dermal/Transdermal10:45- A time-dependent study on the im-11:05 pact of engineering on the physico- chemical characteristics of inhalable particles JoanaPinto,Austria11:05- Solid state transformations of 11:25 dexamethasone induced by milling DrPauloOliveira,France

11:25- How do process parameters 11:45 influencethedensitydistributionin ribbons from roll compaction? RaphaelWiedey,Germany11:45- Influenceofplasticizersondifferent12:05 propertiesoffilmsobtainedfrom film-formingsolutions DrClaire-HélèneBrachais,France12:05- Skin penetration analysis by 12:25 confocalRaman microspectroscopy - potentialsand pitfalls DrDominiqueLunter,Germany12:25- An in vivo study investigating the 12:45 translational potential of microneed- les for use in the older population DrHelenQuinn,NorthernIreland

12:45 - 15:00 Lunch/Exhibition/Posters

Invited talks: Novel strategies toovercome physiological barriers15:00– Oral delivery of macromolecules15:40 DrLaurentHortala,Sanofi,France15:40- Drug delivery to the lung16:20 ProfClaus-MichaelLehr,Helmholtz Center,Saarbrücken,Germany16:20- Drug delivery to the skin and skin 17:00 appendages ProfChristelMüller-Goymann, UniversityofBraunschweig,Germany

Short talks:Oral Delivery15:00- A comparative study between melt 15:20 granulation/compression, hot melt extrusion and injection molding for the manufacturing of oral sustained release polyurethane matrices GlennVerstaete,Belgium15:20- Simulatingzeroorderdrugrelease15:40 via pharmaceutical hot melt extru- sion and 3D printing technology DrMichaelRepka,USA

Programme

15:40- Improving drug release and stability16:00 of solid lipid dosage forms DrAndreasZimmer,Austria16:00- Xanthan gum as rate-controlling 16:20 polymerfor alcohol resistant theophylline matrixtablets AlessiaLazzari,Germany16:20- Individualizedmedicationswith16:40 poorlywater-soluble APIs - Instant ODFs DeniseSteiner,Germany16:40- Noveldissolutionmethodfororalfilm17:00 preparationswithmodifieddrug release IsabellSpeer,Germany

17:15 - 20:00 Welcome Reception

Tuesday, 4 April 2017

Invited talks: Enabling technologiesfor poorly bioavailable drugs09:00- New clothes for the emperor: Novel09:40 approaches to amorphous and lipid base drug delivery ProfThomasRades,University Copenhagen,Denmark09:40- Industrial case studies on poorly10:20 bioavailable drugs DrGeertVerreck,J&J,Belgium10:20- Nanofibertechnologiesfor 11:00 poorly soluble drugs ProfDuncanCraig,UCLLondon, UnitedKingdom

Short talks:Nanoparticles & Vesicles09:00- Dispensing, depositioning and 09:20 downstream processing of drug nanosuspensions into solid oral dosage forms BastianBonhoeffer,Switzerland09:20- Encapsulation of a lipophlic prodrug 09:40 of dexamethasone in to PLGA-PEG nanoparticles: formulation, pharmacokinetics and anti- inflammatoryefficacy ProfEliasFattal,France09:40- Chitosan nanospheres containing10:00 cyclodextrins for idebenone delivery ProfCinziaAnnaVentura,Italy10:00- Dual targeting of polyacrylamide-10:20 paclitaxel nanoparticles to colon cancer cells ProfAbrahamRubinstein,Israel10:20- Evaluation of nanostructured lipid 10:40 carriers(NLC) as tools for ophthalmic administration of N-palmytoil- ethanolamide (PEA) ProfCarmeloPuglia,Italy10:40- Promoting vaginal distribution of two 11:00 active siRNA-complexed in lipo- somes for cervical cancer treatment DrAnnaLechanteur,Portugal

11:00 - 11:30 Coffee/Exhibition/Posters

11:30 - APGI Young Investigator Award11:45 JDDST Best Paper Award Honoring Professor A. T. Florence

Plenary lecture11:45- Smart Devices from an industrial12:45 perspective DrKarymElSayed,Bayer,Germany

12:45 - 15:00 Lunch/Exhibition/Posters

Invited talks: Novel delivery strategies for Non-Lipinski molecules15:00- Overcoming biological barriers in 15:40 cancer through tailored nanoparticles ProfFabianaQuaglia,Universityof Naples,Italy15:40- Peptide Delivery: where do we 16:20 stand and what are the next steps DrJoelRichard,Ipsen,France16:20- Supramulecular harnessed 17:00 architectures for active drug delivery ProfPaoloCalicetti,Padua,Italy

Short talks: Manufacturing & Engineering and Advanced Drug Delivery15:00- Development of an original thermo-15:20 forming apparatus to be coupled to hot melt extrusion for the continuous productionofitraconazole-based amorphous solid dispersions JustinThiry,PhD,Belgium15:20- Comparison of Science-based cali-15:40 bration(SBC) and PLS for coloured coating thickness determination using in-line Raman spectroscopy ShirinBarimani,Germany15:40- Mechanicalcharacterizationof16:00 on-demand printed orodispersible filmsusinga3Dbioprintey HeidiÖblom,Finnland16:00- Composite coating for long-term pre-16:20 vention of foreing body reaction du- ring continuous glucose monitoring ProfDianeBurgess,UnitedStates16:20- Bioavailabilityoftadalafiluponco-16:40 processing with Soluplus: Impotance of the manufacturing procedure AnnaKrupa,PhD,Poland16:40- A novel method for demonstrating 17:00 bioequivalence of locally acting lozenges-frommethoddesigntoa linear level a IVIVC KatharinaTietz,Germany

17:00 End of conference

Posters

Posterswillbepresentedduringspecialsessions.

Chairs and Committees

Chair of the ConferenceProfRenataJachowicz,Poland

Co-Chairs of the ConferenceProfJörgBreitkreutz,GermanyProfAnnaMariaFadda,ItalyProfJürgenSiepmann,France

Programme Committee ChairProfAnnaMariaFadda,Italy

Honorary PatronageProfdrhab.med.WojciechNowakRectoroftheJagiellonianUniversity,Poland

LocalOrganizingCommitteeProfRenataJachowiczDrWitoldJamrózDrAleksanderMendykMgrMateuszKurekMgrWitoldBrniakMgrAgataAntosik

Programme CommitteeDrStefanBracht,GermanyProfJörgBreitkreutz,GermanyProfAnnaMariaFadda,ItalyProfMassimoFresta,ItalyProfRenataJachowicz,PolandDrPascalOury,FranceProfJürgenSiepmann,France

Accompanying Exhibition & Sponsoring

We invite you to join this state-of-the-art industrial exhibitionCoffeeandlunchbreaksaswellastheWelcomeReceptionareincludedintheregistrationfeeandwillbeintegrateintheexhibition/posterareatocreateasmuchtrafficaroundyourboothaspossible.

Take advantage of this great event to showcase your company and your products to an international and very versatile audience!

Current floor plan with available boothscanbedownloadedasaPDFfilefromtheexhibitionsectionofourwebsitehttp://www.europeanmeeting.org/home/exhibition-sponsoring/floorplanorgetintouchwithAntoniaHerbert.

Ifyouwishtoknowmoreabouttheexhibtionandsponsoringship opportunitiesorifyoudesiretobookanadvertisingpossibilitytailoredtoyourspecification,pleasedonothesitatetocontact:

APV InternationalAssociationforPharmaceuticalTechnology Wekindlythankoursponsors:AntoniaHerbertPhone:+4961319769-90E-mail:ah@apv-mainz.de

Venue ICE KRAKÓW (InternationalConferencesandEntertainment)ul.MariiKonopnickiej17,Kraków30-302www.icekrakow.pl

Headquarter HotelPark Inn By Radisson KrakowUl.MonteCassino2,Krakow,30-337|+48123755555www.parkinn.com/hotel-krakow

ICECongressCenterislocatedonlyafewsteps(20m)fromthehotel.90.00Europernightandroomfrom2-4April2017.Pricerateavailableuntil5February2017.Pleasenotethattheroomsarelimited.Reservations Department:Phone:+48123755571,72,73e-mail:reservations.krakow@rezidorparkinn.com

Registration FeesAllcoffeeandlunchbreaksaswellasthewelcomereceptionareincludedintheregistrationfeesandwillbeheldintheindustrialexhibitionandposterpresentationareainordertofacilitatediscussionsbetweenparticipants,exhibi-torsandpresenters.

Full participation until 31 January 2017 from 1 February 2017 presenter participant presenter participantStudent1 member2 260.00€ 290.00€ 310.00€ 340.00€ non-member 460.00€ 490.00€ 510.00€ 540.00€Academia member2 460.00€ 490.00€ 560.00€ 590.00€ non-member 760.00€ 790.00€ 860.00€ 890.00€Industry member2 1,260.00€ 1,290.00€ 1,360.00€ 1,390.00€ non-member 1,560.00€ 1,590.00€ 1,660.00€ 1,690.00€

1 Students are requested to send a copy of their valid student card/pass or a written confirmation of their supervisor.Studentrateonlyavailableforfulltimestudents.2 Membersofallparticipatingsocieties