kidney stones in the adolescent patient
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Morning Report
Erin Fuchs
PGY2January 15, 2014
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Case/History 15 year old female who presents with acute
onset worsening abdominal pain Had initially begun around 11am at school
Ate lunchnot all of it, but some, but pain
continued to worsen Mom picked up after school, brought home, and
pain has since continued increasing
Presents to the ED at approximately 6-7PM with
10/10 right lower quadrant abdominal pain thatradiates to her back.
Since coming home from school she has hadnausea and vomiting x2 secondary to pain
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ROS: Positive for abdominal pain radiating toback, nausea/vomiting x2. Otherwise negative
MEDS: Synthryoid, Advil (400mg day before),Excedrin Migraine
ALL: NKDA
PMH: Hypothryoidism, otherwise negativeIMMS: UTD
FHx: Negative for GI disorders or other chronic
illnessesSHx: Not currently or ever sexually active; noconcerns about STI or pregnancy; Regularperiods; denies tobacco, alcohol, or illicit drugs
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Physical Exam
WT: 41.9 kg, T 36, HR 80, RR 20, SpO2 RA GEN: Writhing on bed, cannot appear to find a
comfortable position, occasionally crying
HEENT: NCAT, PEERLA, EOMI, TMs clear, OP pink
w/o exudate or erythema, MMM NECK: FROM, (-)cervical LAD
CV: RRR, S1, S2, (-)murmur, 2+ radial pulses
RESP: CTAB, (-)wheeze, rhonchi, crackles
GI: BS+, soft, nondistended, negative HSM. TTPesp in RLQ and LLQ
BACK: +Right flank pain
EXT: WWP
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15 year old female with acute onset
right quadrant abdominal pain
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DDxInfectious Disease:
Gastroenteritis Viral Illness
Appendicitis
Pneumonia
Hepatitis
Pharyngitis
Gastrointestinal: Constipation
Intraabdominal abscess
Cholecystitis
Pancreatitis
Perforated ulcer
Abdominal migraine
IBD
Primary Bacterial Peritonitis
MeckelsDiverticulum
CV:
Myocarditis
Pericarditis
MISC:
Trauma Adhesions
Sickle cell syndromevasoocclusive crisis
Familial Mediterranean fever
ENDO/RENAL: UTI
Urolithiasis
DKA
Henloch SP
HUS
OB/GYN:
Ovarian torsion
Ruptured ovarian cyst
Ectopic pregnancy
Labor
Pelvic Inflammatory Disease
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Studies
CBC: WBC 5.7 (N65%, L26%, M7%), Hgb 12.2, Hct35, Plts 185
CRP:
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Imaging US Appendix: Tubular structure projecting in right lower
abdomen. This is believed to represent the distal rightureter rather than appendix, given dilatation of right renalcollecting system and proximal ureter. No distal ureteralstone seen.
-> increased bladder distention
US Pelvis: Normal of uterus and ovaries; probable dilatedright ureter. Suspicious for renal stone
CT without contrast: Mild pelviectasis of right kidney and ureterectasis of proximal
right ureter. No renal or ureteral stone
3 calcifications in region of cecum and terminal ilium -> likelyfecaliths. No dilated appendix.
No etiology for abdominal pain seen.
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Kidney StonesDefinitions:
Urolithiasis: renal stones at
any location within the
urinary tract
Nephrolithiasis: stones
formed exclusively in the
kidneyNephrocalcinosis:
deposition of calcium salts
in the renal parenchyma,
including the tubular lumen,
tubular epithelium, and
interstitium
Deposits usually are
either calcium oxalate
or calcium phosphate
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Epidemiology
Ages 10-19 = 4% of total episodes of
nephrolithiasis
Boys more affected at younger ages (up to 10
yo)
More common in Caucasians
Most common stone:
Calcium oxalate (45-65%)
Calcium phosphate (14-30%)
Struvite (13%)
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Presentation
Depends on age:
Younger kidsdont often see radiating flank pain
Inverse relationship between age and pain (60, 40, 20%
in adolescents, school-age,
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Evaluation/Diagnosis Good History Previous renal stone, family history,
abnormalities, metabolic conditions,medications, recurrent UTIs
PE Labs
UA
Ucx
Serum Creatinine Imaging
Abdominal X-rayRadiopaquestones
Ultrasoundlimited to radiolucentstones and urinary obstruction
Noncontrast CTmost sensitive
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Acute Management
Pain management NSAIDs
Opiods
Passage Most
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Prevention
2/3 patients developed 1 or more additionalstones within 5 years
Evaluate underlying risk factors: Stone analysis
Metabolic evaluation Serum tests: Ca, Phos, HCO3, Cr, Mg, Uric Acid
Urine tests 24-hour urine collections
Interventions: Fluid Intake
Metabolic
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References
Barr, Ronald. "Abdominal Pain in the Female Adolescent." Pediatrics in Review. 4.9(1983): 281-289. Web. 15 Jan. 2014.
Ferry, George. "Causes of acute abdominal pain in children and adolescents."UpToDate. Wolters Kluwer Health, 19 Aug 2013. Web. 15 Jan 2014.
Fishman, Mary, Mark Aronson, and Mariam Chacko. "Chronic abdominal pain inchildren and adolescents: Approach to the evaluation." UpToDate. Wolters
Kluwer Health, 19 Dec 2013. Web. 14 Jan 2014. Lendvay, Thomas, Jodi Smith, and F Bruder Stapleton. "Acute management of
nephrolithiasis in children." UpToDate. Wolters Kluwer Health, 18 Jun 2013.Web. 15 Jan 2014.
McKay, Charles. "Renal Stone Disease." Pediatrics in Review. 31.5 (2010): 179-188.Web. 15 Jan. 2014.
Smith, Jodi, and F Bruder Stapleton. "Clinical featurs and diagnosis of
nephrolithiasis in children. UpToDate. Wolters Kluwer Health, 03 Jun 2013.Web. 15 Jan 2014.
Smith, Jodi, and F Bruder Stapleton. "Epidemiology of and risk factors fornephrolithiasis in children." UpToDate. Wolters Kluwer Health, 29 Aug 2013.Web. 15 Jan 2014.
Smith, Jodi, and F Bruder Stapleton. "Prevention of recurrent nephrolithiasis inchildren. UpToDate. Wolters Kluwer Health, 03 Jun 2013. Web. 15 Jan 2014.
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The EndThink Happy Thoughts .