kidney stones in the adolescent patient

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    Morning Report

    Erin Fuchs

    PGY2January 15, 2014

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    Case/History 15 year old female who presents with acute

    onset worsening abdominal pain Had initially begun around 11am at school

    Ate lunchnot all of it, but some, but pain

    continued to worsen Mom picked up after school, brought home, and

    pain has since continued increasing

    Presents to the ED at approximately 6-7PM with

    10/10 right lower quadrant abdominal pain thatradiates to her back.

    Since coming home from school she has hadnausea and vomiting x2 secondary to pain

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    ROS: Positive for abdominal pain radiating toback, nausea/vomiting x2. Otherwise negative

    MEDS: Synthryoid, Advil (400mg day before),Excedrin Migraine

    ALL: NKDA

    PMH: Hypothryoidism, otherwise negativeIMMS: UTD

    FHx: Negative for GI disorders or other chronic

    illnessesSHx: Not currently or ever sexually active; noconcerns about STI or pregnancy; Regularperiods; denies tobacco, alcohol, or illicit drugs

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    Physical Exam

    WT: 41.9 kg, T 36, HR 80, RR 20, SpO2 RA GEN: Writhing on bed, cannot appear to find a

    comfortable position, occasionally crying

    HEENT: NCAT, PEERLA, EOMI, TMs clear, OP pink

    w/o exudate or erythema, MMM NECK: FROM, (-)cervical LAD

    CV: RRR, S1, S2, (-)murmur, 2+ radial pulses

    RESP: CTAB, (-)wheeze, rhonchi, crackles

    GI: BS+, soft, nondistended, negative HSM. TTPesp in RLQ and LLQ

    BACK: +Right flank pain

    EXT: WWP

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    15 year old female with acute onset

    right quadrant abdominal pain

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    DDxInfectious Disease:

    Gastroenteritis Viral Illness

    Appendicitis

    Pneumonia

    Hepatitis

    Pharyngitis

    Gastrointestinal: Constipation

    Intraabdominal abscess

    Cholecystitis

    Pancreatitis

    Perforated ulcer

    Abdominal migraine

    IBD

    Primary Bacterial Peritonitis

    MeckelsDiverticulum

    CV:

    Myocarditis

    Pericarditis

    MISC:

    Trauma Adhesions

    Sickle cell syndromevasoocclusive crisis

    Familial Mediterranean fever

    ENDO/RENAL: UTI

    Urolithiasis

    DKA

    Henloch SP

    HUS

    OB/GYN:

    Ovarian torsion

    Ruptured ovarian cyst

    Ectopic pregnancy

    Labor

    Pelvic Inflammatory Disease

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    Studies

    CBC: WBC 5.7 (N65%, L26%, M7%), Hgb 12.2, Hct35, Plts 185

    CRP:

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    Imaging US Appendix: Tubular structure projecting in right lower

    abdomen. This is believed to represent the distal rightureter rather than appendix, given dilatation of right renalcollecting system and proximal ureter. No distal ureteralstone seen.

    -> increased bladder distention

    US Pelvis: Normal of uterus and ovaries; probable dilatedright ureter. Suspicious for renal stone

    CT without contrast: Mild pelviectasis of right kidney and ureterectasis of proximal

    right ureter. No renal or ureteral stone

    3 calcifications in region of cecum and terminal ilium -> likelyfecaliths. No dilated appendix.

    No etiology for abdominal pain seen.

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    Kidney StonesDefinitions:

    Urolithiasis: renal stones at

    any location within the

    urinary tract

    Nephrolithiasis: stones

    formed exclusively in the

    kidneyNephrocalcinosis:

    deposition of calcium salts

    in the renal parenchyma,

    including the tubular lumen,

    tubular epithelium, and

    interstitium

    Deposits usually are

    either calcium oxalate

    or calcium phosphate

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    Epidemiology

    Ages 10-19 = 4% of total episodes of

    nephrolithiasis

    Boys more affected at younger ages (up to 10

    yo)

    More common in Caucasians

    Most common stone:

    Calcium oxalate (45-65%)

    Calcium phosphate (14-30%)

    Struvite (13%)

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    Presentation

    Depends on age:

    Younger kidsdont often see radiating flank pain

    Inverse relationship between age and pain (60, 40, 20%

    in adolescents, school-age,

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    Evaluation/Diagnosis Good History Previous renal stone, family history,

    abnormalities, metabolic conditions,medications, recurrent UTIs

    PE Labs

    UA

    Ucx

    Serum Creatinine Imaging

    Abdominal X-rayRadiopaquestones

    Ultrasoundlimited to radiolucentstones and urinary obstruction

    Noncontrast CTmost sensitive

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    Acute Management

    Pain management NSAIDs

    Opiods

    Passage Most

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    Prevention

    2/3 patients developed 1 or more additionalstones within 5 years

    Evaluate underlying risk factors: Stone analysis

    Metabolic evaluation Serum tests: Ca, Phos, HCO3, Cr, Mg, Uric Acid

    Urine tests 24-hour urine collections

    Interventions: Fluid Intake

    Metabolic

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    References

    Barr, Ronald. "Abdominal Pain in the Female Adolescent." Pediatrics in Review. 4.9(1983): 281-289. Web. 15 Jan. 2014.

    Ferry, George. "Causes of acute abdominal pain in children and adolescents."UpToDate. Wolters Kluwer Health, 19 Aug 2013. Web. 15 Jan 2014.

    Fishman, Mary, Mark Aronson, and Mariam Chacko. "Chronic abdominal pain inchildren and adolescents: Approach to the evaluation." UpToDate. Wolters

    Kluwer Health, 19 Dec 2013. Web. 14 Jan 2014. Lendvay, Thomas, Jodi Smith, and F Bruder Stapleton. "Acute management of

    nephrolithiasis in children." UpToDate. Wolters Kluwer Health, 18 Jun 2013.Web. 15 Jan 2014.

    McKay, Charles. "Renal Stone Disease." Pediatrics in Review. 31.5 (2010): 179-188.Web. 15 Jan. 2014.

    Smith, Jodi, and F Bruder Stapleton. "Clinical featurs and diagnosis of

    nephrolithiasis in children. UpToDate. Wolters Kluwer Health, 03 Jun 2013.Web. 15 Jan 2014.

    Smith, Jodi, and F Bruder Stapleton. "Epidemiology of and risk factors fornephrolithiasis in children." UpToDate. Wolters Kluwer Health, 29 Aug 2013.Web. 15 Jan 2014.

    Smith, Jodi, and F Bruder Stapleton. "Prevention of recurrent nephrolithiasis inchildren. UpToDate. Wolters Kluwer Health, 03 Jun 2013. Web. 15 Jan 2014.

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    The EndThink Happy Thoughts .