key stage 4 magnetic resonance imaging watching the brain at work

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Key Stage 4 Magnetic Resonance Imaging Watching the brain at work www.oxfordsparks.net/mri

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Page 1: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work

Key Stage 4

Magnetic Resonance Imaging

Watching the brain at work

www.oxfordsparks.net/mri

Page 2: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work

If you wiggle your fingers……there is more activity in these brain

areas.

www.oxfordsparks.net/mri

Page 3: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work

These areas of the brain need more oxygen…

activation statebaseline

More blood flow

More oxygenated blood

Less distortion of magnetic field

More fMRI signal

…which the blood delivers

www.oxfordsparks.net/mri

Page 4: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work

An experiment

rest move rest move rest move restTask FMRI signal

time

These areas of the brain are active

during movement, but not rest.

www.oxfordsparks.net/mri

Page 5: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work

The FMRI scanner looks at one brain ‘slice’ at a time…

www.oxfordsparks.net/mri

Page 6: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work

You can locate an area of the brain using X, Y, and Z co-ordinates.

The image is divided into

voxels. Voxels are 3D pixels.

www.oxfordsparks.net/mri

Page 7: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work

The trace shows that this voxel is relevant to the task.

www.oxfordsparks.net/mri

Page 8: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work

Colour Vision• FMRI does not give an

absolute measure, so you need to look at signal change.

• To isolate one brain function, compare the condition you are investigating to a control condition.

www.oxfordsparks.net/mri

Page 9: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work

The subtraction approach: vision

View grey

stimuli (control)

View colourstimuli

grey colour grey colour grey colour greyTask:fMRI signal

time

www.oxfordsparks.net/mri

Page 10: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work

The subtraction approach: vision

- =

www.oxfordsparks.net/mri