key slides leg ulcer (2)

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    Wounds: Leg ulcers

    Key slides

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    Wound care: leg ulcersNHS CRD (1997) Effective Healthcare 3 (4), 1-12

    SIGN 26 (1998) The Care of patients with Chronic Leg Ulcer

    Clinical Knowledge Summaries_Venous Leg Ulcer_Feb 08

    Wound care is a high cost area for patients and NHS in terms of

    prescribing costs, patient QoL and NHS workforce time

    The evidence base for therapeutics in much of this area is

    limited Value for money for the NHS is an important factor when

    choosing treatments

    Leg ulcers are a common, chronic, recurring condition

    Prevalence of active leg ulcers is between 1.5 to 3 per 1000 and

    increases with age. Its estimated that up to 20 per 1000people over 80 yrs will suffer from a leg ulcer

    Following healing, re-ulceration rates at one year range from

    26% - 69%

    Available treatments can reduce recurrence rates

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    Leg ulcer aetiologyClinical Knowledge Summary Venous Leg Ulcers_February 2008

    Grey J.E et al. ABC Wound Healing BMJ 2006; 332: 347-50

    Venous insufficiency 80 - 85%

    Other causes:

    Arterial disease

    Mixed arterial and venous disease Diabetes

    Rheumatoid arthritis

    Systemic vasculitis

    Lymphoedema Trauma

    Others including malignancy

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    Assessment of the patient - historyClinical Knowledge Summary Venous Leg Ulcers_February 2008

    Royal College of Nursing Clinical Practice Guidelines 2006

    History suggesting venous

    disease

    History suggesting arterial

    disease (c.10-20% patients)

    Varicose veins, immobility, obesity Ankle Brachial Pressure Index less

    than 0.8

    Proven deep vein thrombosis in the

    affected leg

    Ischaemic heart disease, stroke or

    transient ischaemic attack

    Phlebitis in the affected leg Rheumatoid arthritis

    Previous fracture, trauma, or

    surgery

    Diabetes mellitus

    Family history of venous disease Peripheral arterial

    disease/intermittent claudication

    Symptoms of venous insufficiency:

    leg pain, heavy legs, aching,

    itching, swelling, skin breakdown,

    pigmentation, and eczema

    Smoking

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    Assessment of the leg - examinationClinical Knowledge Summary Venous Leg Ulcers_February 2008

    CREST Guidelines for the Assessment and Management of Leg Ulcers 1998

    Measurement of Ankle Brachial Pressure Index (ABPI) is the most

    reliable way to detect arterial insufficiency

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    Assessment of the ulcerClinical Knowledge Summary Venous Leg Ulcers_February 2008

    CREST Guidelines for the Assessment and Management of Leg Ulcers 1998

    RECORD RATIONALE

    Size, depth, edges and site of ulcer Serial measures useful for progress

    Ulcer base:

    Epithelialisation/granulation/slough/

    eschar/necrosis

    Aid choice of dressing and indicate

    progress of healing

    Level of exudate:

    Minimal/ moderate/ high

    Will influence dressing choice and

    frequency of dressing change

    Signs of infection:

    Enlarging ulcer, increased exudate,

    pyrexia, foul odour, cellulitis

    May indicate infection

    Pain:

    Assess level, frequency and duration

    Treat to relieve distress and aid

    compliance with treatment

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    Referral to a specialist clinic before treatmentClinical Knowledge Summary Venous Leg Ulcers_February 2008

    Uncertain diagnosis

    Suspected alternative causes of ulceration:

    - Arterial or mixed venous/arterial ulcer. Refer people with

    ABPI

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    Lifestyle adviceClinical Knowledge Summary Venous Leg Ulcers_February 2008

    Self - care strategies include:

    Keep mobile with regular walking if possible

    Elevate legs when immobile Use emollient and examine legs regularly for broken skin,

    blisters, swelling or redness

    Lose weight if appropriate

    Stop smoking

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    Venous leg Ulcer - treatmentClinical Knowledge Summary Venous Leg Ulcers_February 2008

    Irrigate the wound with warm tap water or saline, then dry. Strictaseptic technique not required

    Remove slough or necrotic tissue by gentle washing

    If debridement is needed, it should be carried out by a trainedhealthcare professional

    Consider using potassium permanganate 0.01% soak if theulcer is malodorous

    For uncomplicated, non-infected ulcers apply a low-adherentdressing & replace weekly. (If heavy exudate - more frequentchange)

    Other dressings may be used if needed - pain (hydrocolloid),heavy exudate (alginate) or slough (hydrogel)

    For uncomplicated, non infected ulcers and where indicated byABPI, apply compression bandaging - 4 or 3 layer if immobile,or 2-layer if mobile

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    Uncomplicated venous leg ulcer

    Follow up during treatmentClinical Knowledge Summary Venous Leg Ulcers_February 2008

    Assess weekly for the first 2 weeks. If healing underway, assess

    fortnightly or monthly, then 3 monthly

    Change dressings at least once a week. Check for healing

    and compliance with compression therapy and ask aboutproblems e.g. mobility, sleep, mood

    If delayed or no healing, identify problems which may need

    further treatment or referral

    Check for complications

    Check lifestyle advice is followed If ulcer not healing or deteriorating at 12 weeks, look for signs of

    arterial disease and repeat ABPI

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    Venous leg ulcer - treating infectionClinical Knowledge Summary Venous Leg Ulcers_February 2008

    All chronic wounds are colonised with bacteria Antibiotics should be used only if there is evidence of

    cellulitis or active infection (e.g. pyrexia, increasing pain,

    enlarging ulcer)

    If there are clinical signs of infection present, clean ulcer with

    warm tap water or saline before taking a swab Start immediate empiric treatment with an anti-staphylococcal

    antibiotic i.e. flucloxacillin or erythromycin 500mg qds for seven

    days

    Change dressing daily or alternate days to assess if infection is

    improving Do not use antimicrobial dressings

    Do not start compression therapy if ulcer is infected

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    Infected venous leg ulcer- follow up

    during treatmentClinical Knowledge Summary Venous Leg Ulcers_February 2008

    SIGN 26 (1998) The Care of patients with Chronic Leg Ulcer

    Reassessment and follow up frequency is different

    for uncomplicated and infected ulcers

    Review the patient within 3 days to assess response

    to treatment, ideally followed by re-assessment every

    two or three days until clinical improvement is seen

    Reassess the ulcer as at initial assessment:

    dimensions, site, base, odour and exudate

    If infection is not responding, consider change of

    antibiotic based on swab results

    If signs of worsening infection, refer

    After infection has settled, follow up as for

    uncomplicated venous ulcers

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    Venous leg ulcer - dressing choiceSIGN 26 (1998) The Care of patients with Chronic Leg UlcerClinical Knowledge

    Summary Venous Leg Ulcers_February 2008

    There is good evidence that the type of dressing used has

    no effect on ulcer healing

    Uncomplicated ulcer-use simple low-adherent dressing

    Sloughy ulcer-hydrogel provides moisture that may help liquefyslough

    Moderate to heavily exuding ulcer-alginate or foam dressing

    may help absorb exudate

    Painful ulcer-occlusive hydrocolloid or foam dressing may

    reduce pain

    Simple non-adherent dressings are recommended in the

    treatment of venous ulcers as no specific dressing has

    been shown to improve healing rates

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    Venous leg ulcer - compression bandagingClinical Knowledge Summary Venous Leg Ulcers

    Below-knee graduated compression is the mainstay of

    treatment to improve venous return, and to reduce venous

    stasis and hypertension in uncomplicated venous leg

    ulcers

    Graduated compression delivers the highest pressure at theankle and gaiter area (40 mmHg), and pressure progressively

    reduces towards the knee and thigh where less external

    pressure is needed (18 mmHg)

    High compression multilayer(four layer, three layer)

    bandaging has improved healing rates over single layerbandaging

    An appropriately trained personshould apply high

    compression multi-layer bandaging, to avoid the risk of pressure

    ulceration over bony points

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    Venous leg ulcer - preventing recurrenceClinical Knowledge Summary Venous Leg Ulcers_February 2008

    CREST Guidelines for the Assessment and Management of Leg Ulcers 1998

    Graduated compression stockings should be used for at

    least 5 years after ulcer healing

    Educate and explain to the patient the importance of preventing

    recurrence through lifestyle changes and use of hosiery

    Accurate measurement of limbs for compression hosiery is

    essential

    Follow up with 6-monthly Doppler ABPI checks

    Class III (high) compression stockings are associated with lessrecurrence than Class II (medium) compression stockings, but

    may be less acceptable to the patient

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    Arterial leg ulcersGrey J.E et al. ABC Wound Healing BMJ 2006; 332: 347-50

    Caused by reduced blood supply to the lower limbs either by a

    blockin the artery or narrowing of the arteriesresulting in hypoxic

    damage, ulcer formation and necrosis

    Arterial ulcers account for 10% - 15% of leg ulcers

    Typically occur over toes, heels and bony prominences of foot Can take months or years to heal, are painful and often become

    infected

    Men over 45 years and women over 55 years are more likely to have

    PVD, (peripheral vascular disease) and so are prone to arterial leg

    ulcers

    Modifiable risk factors: smoking, hyperlipidaemia, hypertension,

    obesity, diabetes, decreased activity

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    Arterial leg ulcersGrey J.E et al. ABC Wound Healing BMJ 2006; 332: 347-50Nelson EA et al.

    Dressings and topical agents for arterial leg ulcers. Cochrane Database of

    Systematic Reviews 2007, Issue 1.

    Infection can cause rapid deterioration of an arterial

    ulcer

    It is not appropriate to debride arterial ulcers as this

    may produce further ischaemia and formation of a

    larger ulcer (specialist only)

    Compression bandaging should not be applied

    as severe damage to the leg can result

    Choice of dressing is dictated by the nature of the

    wound Treatment options include reconstructive surgery or

    angioplasty

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    Summary: leg ulcer therapeutics

    For both venous and arterial leg ulcers Systematic assessmentof the wound is essential for baseline dataand to evaluate healing and treatment efficacy

    Regular wound reassessmentis good clinical practice

    There is insufficient evidence that one type of dressing is superior toanother in leg ulcer wound healing

    Treat infection with systemic antibiotics not topical antimicrobials

    Management of venous vs. arterial leg ulcers

    Compression therapyis the mainstay of venous leg ulcermanagement, but should not be used for arterial ulceration or infected

    wounds Increasing peripheral blood flowis the intervention most likely to

    affect healing in arterial ulceration