JULIANA FERREIRA DE SOUZA

Neurofibromatosis Outpatient Reference Center Visiting Scholar Minas Gerais Federal University Neuroscape Lab School of Medicine UCSF Belo Horizonte – MG - Brazil SF - CA - USA

Education

Doctor of Philosophy, Science Applied to Health Program, Minas Gerais Federal University, Belo Horizonte, Minas Gerais, Brazil (2013) Master of Science, Internal Medicine Program, Minas Gerais Federal University, Belo Horizonte, Minas Gerais, Brazil (2008) Graduation, Medicine, Minas Gerais Federal University, Belo Horizonte, Minas Gerais, Brazil (1998)

Awards, Grants and Training Best thesis of the year presented for the Science Applied to Health Post Graduation Program, Minas Gerais Federal University (2013) Seven month, merit based, doctoral fellowship, Brazilian National Development Council in Research (CNPq), Science Without Frontiers Scholarship, University of Utah (2012) Best Poster in Clinical Research Award, Children’s Tumor Foundation Conference, Jackson Hole, Wyoming (2011) Doctor of Philosophy Grant, Minas Gerais Foundation for Research Supporting (FAPEMIG), Minas Gerais Federal University, Belo Horizonte, Minas Gerais, Brazil (2009) Specialist in Family Medicine, Brazilian Society of Community and Family Medicine (2005) Specialization in Sports Training, Minas Gerais Federal University, Belo Horizonte, Minas Gerais, Brazil (2004)

Research Experience

Member of the Brazilian Society of Researchers in Neurofibromatosis, Neurofibromatosis Outpatient Reference Center, Minas Gerais Federal University, Belo Horizonte, Minas Gerais, Brazil (2012-Present) Director Dr. Nilton Alves de Rezende Resulted in 1 publications in the Brazilian Archives of Neuro-Psychiatry and 1 article in the submission process for publication Science Applied to the Health Program, Minas Gerais Federal University, Belo Horizonte, Minas Gerais, Brazil (2009-2013) Doctor of Philosophy thesis research conducted with Dr. Nilton Alves de Rezende and Dr. Luiz Oswaldo Carneiro Rodrigues

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Physical fitness is decreased in type 1 neurofibromatosis even in minor cases. Resulted in 1 publications in the American Journal of Medical Genetics Part A and 1 article in the submission process for publication Internal Medicine Program, Minas Gerais Federal University, Belo Horizonte, Minas Gerais, Brazil (2007-2008) Master of Science thesis research conducted with Dr. Nilton Alves de Rezende and Dr. Luiz Oswaldo Carneiro Rodrigues (supervisors) Neurofibromatosis type 1 is more frequent and severe then usually thought. Resulted in 2 publications in the Journal of Musculoskeletal and Neuronal Interactions and in the Journal of Brazilian Medical Association.

Research Interests Degree in Medicine from the Federal University of Minas Gerais (1998), specialization in Sports Training by the Federal University of Minas Gerais (2004), Master of Medicine (Internal Medicine) at the Federal University of Minas Gerais (2008) and PhD in Medicine (Applied Sciences the Adult Health) from the Faculty of Medicine of the Federal University of Minas Gerais, Brazil (2013). PHD fellow (Project Science Without Borders - CNPq) (from September 2012 to February 2013, at the University of Utah (USA). Former Professor of the medical course at the UNIBH University Center (until July 2015). Currently postdoc visiting scholar at the University of California San Francisco (Project Science Without Borders, CNPq, Brazil). Member of the multidisciplinary research group in the Neurofibromatosis Outpatient Reference Center of the Federal University of Minas Gerais, with expertise in Family Medicine and exercise physiology, and special interest in the study of cognitive deficits, cognitive training and physical fitness in Neurofibromatosis type 1.

University Teaching Experience

Assistant professor for the Medicine under graduation course in the discipline of medical semiology. Lectured, supervised and advised students practice, wrote exams Department of Internal Medicine, Instituto Mineiro de Educação e Cultura UNIBH/SA, Belo Horizonte, Minas Gerais, Brazil (2013-Present) Assistant professor for the Medicine under graduation course in the discipline of Public Health. Lectured, supervised and advised students practice, wrote exams Department of Internal Medicine, Instituto Mineiro de Educação e Cultura UNIBH/SA, Belo Horizonte, Minas Gerais, Brazil (2012-Present) Substitute professor for the Medicine under graduation course in the discipline of medical semiology. Lectured, supervised and advised students practice, wrote exams Department of Internal Medicine, Minas Gerais Federal University, School of Medicine, Belo Horizonte, Minas Gerais, Brazil (2010)

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Publications

De Souza JF, Araujo CG, De Rezende NA, Rodrigues LOC. Exercise capacity impairment in individuals with neurofibromatosis type 1. American Journal of Medical Genetics. Part A, v. 161, p. 393-395, 2013. Souza JF, Passos RLF, Rezende NA, Rodrigues LOC. Muscular force is reduced in neurofibromatosis type 1. Journal of Musculoskeletal and Neuronal Interactions, v. 9, p. 15-17, 2009. Souza JF, Toledo LL, Ferreira MCM, Rodrigues LOC, Rezende NA. Neurofibromatosis type 1 more frequent and severe than usually thought. Revista da Associação Médica Brasileira, v. 55, p. 394-349, 2009. Rodrigues LOC; Batista PB, Goloni-Bertollo, EM, Souza-Costa D, Eliam L, Eliam M, Cunha KSG, Garrigo-Junior LG, Ferraz-Filho JRL, Geller M, Gianordoli-Nascimento IF, Madeira LG, Malloy-Diniz LF, Mendes HM, Miranda DM, Pavarino EC, Baptista-Pereira L, Rezende NA, Rodrigues LO, Silva CM, Souza JF, Souza MLR, Stangherlin A, Valadares ER, Vidigal. Neurofibromatosis: part 1 - diagnosis and differential diagnosis. Arquivos de Neuro-Psiquiatria, v. 72, p. 241-250, 2014. Rodrigues LOC; Batista PB, Goloni-Bertollo, EM, Souza-Costa D, Eliam L, Eliam M, Cunha KSG, Garrigo-Junior LG, Ferraz-Filho JRL, Geller M, Gianordoli-Nascimento IF, Madeira LG, Malloy-Diniz LF, Mendes HM, Miranda DM, Pavarino EC, Baptista-Pereira L, Rezende NA, Rodrigues LO, Silva CM, Souza JF, Souza MLR, Stangherlin A, Valadares ER, Vidigal. Neurofibromatosis: part 2 - clinical management. Arquivos de Neuro-Psiquiatria, 2015. Martins AS, Kristine JA, Rodrigues LOC, De Matos CM, Souza MLR, Souza JF, Sander Diniz MFH et al. Lower fasting blood glucose in neurofibromatosis type 1. Endocrine Connections, 2015.

Poster Presentations

Madeira LG, Souza JF, Rezende NA, Rodriges LOC. Heat tolerance is reduced in individuals with neurofibromatosis type 1 (NF1). In: Children's Tumor Foundation Conference, Washington/DC. 2014. v. 1. p. 93-100. Souza JF, Diniz LM, Cunha KSG, Darrigo Junior LG, Passos RLF, Geller M, Rezende NA, Rodrigues LOC. Photographic prevalence of the second toe signal phenotype in neurofibromatosis type 1 (NF1). In: Children's Tumor Foundation Conference, Washington/DC. 2014. v. 1. p. 89-101. Silva CM, Souza JF, Rodrigues LOC, Gama AC, Rezende NA. Orofacial motor function impairment and decreased electrical potential of the masseter muscle correlate with maximal handgrip force in individuals with NF1. In: Children's Tumor Foundation Conference, Washington/DC. 2014. v. 1. p. 87-102.

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Rodrigues LOC, Rezende NA, Geller M, Souza JF, Rodrigues LO, Diniz LM, Passos RLF. Reproducibility of photographic diagnose of the second toe signal phenotype in neurofibromatosis type 1 (NF1). In: 16 European Neurofibromatosis Meeting. Barcelona/Spain. 2014. v. 1. p. 100. Souza JF, Penna JL, Rezende NA, Rodrigues LOC. Myocardial mass and cardiac function echocardiography measurements are similar to unaffected controls. In: Children’s Tumor Foundation Conference. Monterey/CA. 2013. Souza JF, Rezende NA, Rodrigues LOC. Vitamin d levels and maximal handgrip force in adults with neurofibromatosis type 1. In: Children’s Tumor Foundation Conference. Monterey/CA. 2013. v. 1. p. 92. Souza JF, Mancuzo EV, Rezende NA, Rodrigues LOC. Pulmonary function in individuals with neurofibromatosis type 1: a preliminary report. In: Children’s Tumor Foundation Conference. New Orleans/MD. 2012. Souza JF, Mancuzo EV, Rezende NA, Rodrigues LOC. Função pulmonar em indivíduos com neurofibromatose tipo 1. In: XXXVI Congresso Brasileiro de Pneumologia e Tisiologia. Belo Horizonte/MG. 2012. Souza JF, Mancuzo EV, Rezende NA, Rodrigues LOC. Redução da capacidade funcional no teste de caminhada de 6 minutos em individuos com neurofibromatose tipo 1. In: XXXVI Congresso Brasileiro de Pneumologia e Tisiologia. Belo Horizonte/MG. 2012. Souza JF, Araujo CG, Rezende NA, Rodrigues LOC. Aerobic capacity is reduced in patients with neurofibromatosis type 1: a preliminary report. In: Children's Tumor Foundation Conference. Jackson Hole/WY. 2011. v. 1. p. 52. Best poster in clinical research award. Souza JF, Araujo CG, Rezende NA, Rodrigues LOC. Capacidade funcional dos individuos com neurofibromatose tipo 1. In: 2 Congresso Nacional de Saude da Faculdade de Medicina da UFMG. Belo Horizonte/MG. Revista Médica de Minas Gerais. 2011. v. 1. p. 95-95. Souza JF, Rezende NA, Rodrigues LOC. Centro de Referência em Neurofibromatose da UFMG: quatro anos de experiência no atendimento, pesquisa e ensino. In: Congresso Brasileiro de Genética Médica. Belo Horizonte/MG. Revista Médica de Minas Gerais. 2009. v. 19. p. 119. Souza JF, Passos RLF, Toledo LL, Ferreira MCM, Rezende NA, Rodrigues LOC. Vitamin D levels correlates with short stature but not with macrocephaly in NF1 patients. In: Children’s Tumor Foundation Conference. Portland/Oregon. 2009. v. 1. p. 76. Souza JF, Passos RLF, Ferreira MCM, Toledo LL, Rezende NA, Rodrigues LOC. Vitamin d and calcium serum levels in NF1 patients. In: Children’s Tumor Foundation Conference. Portland/Oregon. 2009. v. 1. p. 78.

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Souza JF, Guedes ACM, Rodrigues LOC, Rezende NA. Some under-reported clinical complications in NF1 patients. In: XX NF Conference. Bonita Springs/Florida. 2008. v. 1. p. 140. Souza JF, Guedes ACM, Rodrigues LOC, Rezende NA. A new approach to measure the severity of neurofibromatosis type 1. In: XX NF Conference. Bonita Springs/Florida. 2008. v. 1. p. 141. Souza JF, Passos RLF, Guedes ACM, Rodrigues LOC, Rezende NA. Maximal voluntary muscular strength is reduced in neurofibromatosis type 1 patients. In: XX NF Conference. Bonita Springs/Florida. 2008. v. 1. p. 142. Souza JF, Rezende NA, Rodrigues LOC. A força muscular está diminuída na neurofibromatose tipo 1. In: XXIII Congresso Brasileiro de Neurologia. Anais do XXIII Congresso Brasileiro de Neurologia. São Paulo/SP. 2008. v. 1. p. 1. Souza JF, Toledo LL, Guedes ACM, Rodrigues LOC, Rezende NA. Prevalência de problemas clínico em pacientes brasileiros com neurofibromatose tipo 1. In: 63 Congresso Brasileiro de Dermatologia. Anais Brasileiro de Dermatologia. São Paulo/SP. 2008. v. 83. p. s52. Souza JF, Ferreira MCM, Toledo LL, Passas RLF, Rodrigues LOC, Rezende NA. Manifestações musculoesqueléticas em pacientes com neurofibromatose tipo 1. In: Congresso Brasileiro de Genética. Salvador/BA. 2008. v. 1. p. 1.

Invited Talks

Souza JF. Physical fitness in NF1: a Brazilian perspective. In: Children’s Tumor Foundation Conference. Monterey/CA (2013) Souza, JF. NF1 muscular phenotype: a Brazilian perspective. In: Children’s Tumor Foundation Family Symposium. Salt Lake City/UT (2012) Souza, JF. Neurofibromatose tipo 1: achados, consequencias e complicações. In: Congresso Brasileiro de Neurologia. Rio de Janeiro/RJ (2010)

Language Written and Spoken

Portuguese: Comprehends Well, Reads Well, Speaks Well, Writes Well English: Comprehends Well, Reads Well, Speaks Well, Writes Well French: Comprehends Well, Reads Well, Speaks Reasonably, Writes Reasonably Spanish: Comprehends Well, Reads Well, Speaks Reasonably, Writes Reasonably