journal of drug delivery and therapeutics
TRANSCRIPT
Dakhole et el Journal of Drug Delivery & Therapeutics. 2019; 9(5):213-215
ISSN: 2250-1177 [213] CODEN (USA): JDDTAO
Available online on 15.09.2019 at http://jddtonline.info
Journal of Drug Delivery and Therapeutics Open Access to Pharmaceutical and Medical Research
© 2011-18, publisher and licensee JDDT, This is an Open Access article which permits unrestricted non-commercial use, provided the original work is properly cited
Open Access Review Article
Role of Chitrak in the Management of Skin Problem W.S.R. to Shwitra
Dr. Prashant Dakhole1*, Dr. Pradnya Dakhole2
1 Asso. Prof., Shalya Tantra, Mandsaur Ayurveda College, Mandsaur, India.
2 Asso. Prof., Shalya Tantra, Shri K.R. Pandav Ayurveda College, Nagpur, India.
ABSTRACT
Shwitra is common skin disorders mainly characterized by the presence of lesion or white patches over the skin. Shwitra on the basis of symptomatic similarities can be correlated with vitiligo. Excessive consumption of liquid and heavy foods, intake of salty & sour foods, excessive intake of fish and sweets, exposure to sunlight, genetic factors and autoimmune responses, etc. are some causes which can initiate pathogenesis of Shwitra, in this condition destruction of melanocytes take place. However exact cause of Shwitra is still to know. Ayurveda described various treatment modalities for the management of Shwitra; Chitrak (Plumbago zeylanica) is one such herb which offers beneficial effect in the management of vitiligo. Considering this aspect present article emphasizes role of Chitrak in the management of vitiligo.
Keywords: Ayurveda, Shwitra, Vitiligo, Chitrak, Plumbago zeylanica.
Article Info: Received 19 July 2019; Review Completed 17 Aug 2019; Accepted 22 Aug 2019; Available online 15 Sep 2019
Cite this article as:
Dakhole P, Dakhole P, Role of Chitrak in the Management of Skin Problem W.S.R. to Shwitra, Journal of Drug Delivery and Therapeutics. 2019; 9(5):214-216 http://dx.doi.org/10.22270/jddt.v9i5.3670
*Address for Correspondence:
Dr. Prashant Dakhole, Asso. Prof., Shalya Tantra, Mandsaur Ayurveda College, Mandsaur, India.
Introduction
The word Switra means Shweta and disease Switra technically resembles whiteness of the skin or white patches over skin. Switra (Vitiligo) characterized as whitish colored patches over skin without any pain or secretions. The milky white macules smaller than 0.5cm or patches larger than 0.5cm may be observed in disease condition. Pathologically disease involves gradual destruction of melanocytes of epidermis leading to hypopigmentation or depigmented patches over skin. The Switra physically not produces any harmful effects but it greatly affects quality of life due to the psychological depression associated with disease condition [1-5].
The word Switra can be elaborated by using quote “Shweta Bhava Micchanti Switra” which means reflection of white colour. Charaka Samhita mentioned Tridoshaja involvement in Switra along with Rakta, Maamsa and Medadhatugat vitiation. The fourth layer of Twacha (Tamra) mainly considered as prime location of Switra.
Ayurveda mentioned therapeutic approaches such as; Shodhana and Shaman Chikitsa for the management of various skin problems. In this regards natural drug Chitrak
(Plumbago zeylanica) also recommended alone or in combination for the treatment of Switra.
Plumbago zeylanica (Chitrak) is a plant belonging from family Plumbaginaceae, offers several medicinal importance including health benefits in skin problems. Chitrak traditionally recommended for various therapeutic purposes in case of Grahani Roga, Agnimandya, Udara Sula, Arsa and Gudasotha. This plant mainly found in tropical and subtropical countries, is also found in West Bengal, Maharashtra and some parts of South India. The root of plant employed mainly for various therapeutic purposes. The major phytoconstituents of plant are Plumbagin, Chitranone, Plumbagic Acid, Hydroxyproline, Maritone, Dihydrosterone, B- Sitosterol and Zeylanone etc [2-7].
Chitrak is used for the management of various health problems like; nausea, indigestion, abdominal cramps, osteoarthritis, hemorrhoids, ulcer, skin disease and leprosy, etc. It can be used as liver tonic and helps to control level of cholesterol. Chitrak offers various therapeutic benefits in skin and other problems as depicted in Figure 1.
Dakhole et el Journal of Drug Delivery & Therapeutics. 2019; 9(5):213-215
ISSN: 2250-1177 [214] CODEN (USA): JDDTAO
Figure 1: Therapeutic benefits of Chitrak.
Chitrak in Shwitra:
Chitrak offers beneficial effects in Shwitra since it offers Tridoshghana effect, mainly pacifies Kapha & Vata Dosha, control vitiated Vayu and helps to maintain normal circulatory functioning of body. As per Ayurveda Chitrak offers health benefits in skin problem due to its inherent properties which are as follows:
Rasa: Katu
Guna: Laghu, Tiksna, Ruksa
Vipaka: Katu
Virya: Usna
Karma: Sothahara, Grahi, Kaphavatahara, Arsohara and Sulahara.
Chitrak helps to treat Shwitra since it offers following health benefits in skin problem:
The heating effect of Chitrak boosts circulatory process thus removes skin ailments.
It enhances metabolism and remove toxins from the body thus improves skin health by detoxification process.
It improves digestion thereby regulate nutritional supply, maintain colour and texture of skin
The anti-inflammatory and antibacterial properties of Chitrak provide calming and soothing effects in skin problems.
The vitiation of Kapha and Vata is main Doshic involvement in Shwitra, Chitrak pacifies Kapha and Vata thus control disease from its root cause. Plumbago zeylanica provides strength to immune system due to the presence of plumbagin therefore protect skin from microbial susceptibility. It protects body from environmental toxins and prevent free radicals induce damage of tissue. It reduces inflammatory process inside the body thus protects from skin ailments such as; vitiligo.
There are various commercial formulations used for skin ailments containing Chitrak as ingredient such as; Punarnavadi Guggulu, Yogaraj Guggulu, Kapha massage oil, Punarnavadi Guggulu powder and Yogaraj Guggulu powder. The bitter taste, pungent metabolites and heating effect of Chitrak help to balance Kapha and Vata thus relieve skin manifestation of vitiligo [6-10].
The other formulations containing Chitrak can be used in vitiligo are as follows:
1. Formulations containing Chitrak used in Shamana Chikitsa of Shwitra:
a. Manjishthadi Kwath / Churna
It contains Chitraka root along with Bakuchi seeds, Neem bark, Go-mutra, Hasthi-mutra and Sasyaka.
b. Mahakashaya Yoga
It contains Chitraka along with Manjishtha, Adusa, Nimba, Triphala, Haldi, Khadir, Kutaki, Giloya, Baakuchi, Murva, Danti, Amaltasa, Patolpatra, Peepal and Anantamula.
c. Go-mutrasava
It contains Chitraka along with Go-mutra, Shunthi, Marich and honey.
2. Formulations for local application can be used in Shwitra:
a. Yoga for Shwitra containing Chitrak
It contains Chitrak mool along with Baakuchi beej, Chakramard beej, Tulsi beej, Jeeraka, Neem beej, Khadir twak, Gairik bhasma, Erand beej and Gandhak.
b. Gutika for Shwitra containing Chitrak
It contains Chitrak mixed with Gomutra and other ingredients such as; Avalgujadi gutika Baakuchi, Mainshila, Hartal and Gunja root.
c. Ghrita for Shwitra containing Chitrak
It contains Chitrak along with Triphala, Tulsi, Amaltasa, Makoya, Trikatu, Kutaj, Mehndi, Danti, Madaar and Daruhaldi.
d. Bhallatakadi lepa for Shwitra containing Chitrak
It contains Chitrak along with Bhallataka, Snuhi root, Arka root, Maricha, Shankh, Tuttha, Pippali, Salts, Sarjikshara, Kalihari and Yavakshara.
Conclusion
Shwitra is one of the common skin problem symptomatically correlates with vitiligo. Excessive consumption of heavy, oily, salty & sour foods, exposure to sunlight, genetic factors and environmental effects, etc. are some factors which can trigger pathogenesis of Shwitra. Ayurveda described various approaches for the management of Shwitra including use of natural drugs such as; Chitrak (Plumbago zeylanica). Chitrak helps to treat Shwitra since it offers health benefits in various skin ailments. It removes toxins from the body, improves digestion, regulates nutritional supply, imparts anti-inflammatory and antibacterial properties, provide calming and soothing effects. Chitrak provides strength to
Detoxification Immune booster
Anti-inflammatory
Anti-bacterial
Tridoshghana
Dakhole et el Journal of Drug Delivery & Therapeutics. 2019; 9(5):213-215
ISSN: 2250-1177 [215] CODEN (USA): JDDTAO
immune system thus protect skin from microbial susceptibility, it protects body from the damage induced by free radicals, pacifies Kapha and Vata and detoxifies body thus maintain colour and texture of skin. Article concluded that Chitrak can be used as alternative therapeutic measure for the management of skin disease like; Shwitra.
References
1. Vijver LM. Antibacterial Activity in Roots of Plumbago zeylanica. Planta Med, 1971; 20: 8-13.
2. Yuvaraj D. Mandavkar and Sunil S. Jalalpure. A comprehensive review on Plumbago zeylanica Linn. African journal of Pharmacy and Pharmacology African Journal of Pharmacy and Pharmacology, 2011; 5 (25): 2738-2747.
3. Dhale, D.A, Markandeya SK. Antimicrobial and phytochemical screening of Plumbago zeylanica Linn. (Plumbaginaceae) Leaf. Journal of Experimental Sciences, 2011; 2(3): 4-6.
4. Pole, Sebastian. Ayurvedic Medicine: The Principles of Traditional Practice. London: Churchill Livingston, 2006. Print. 44-46, 103-105.
5. Chunekar K.C., Bhavaprakasa Nighantu, Chaukhambha Bharti Academy Varanasi, edited by Dr G.S Pandey, Reprint: 2015, P.21
6. Shastri A.,kushthanidanam. Sushrut Samhita, Ayurvedatatva-sandipika vol.1. Chaukhambha Sanskrit, Varanasi. 2010; 5/17. p. 323
7. Trivedi S. D., Atharvaveda, hindi commentary Aarya prakashan Ajmery gate Delhi. Revised2012. First kanda sukta 23/4: 98
8. Tripathi J. P., Kushtha Chikitsa. Mishra B. S. (ed.). Chakrdatta, Bhavarth-sandipini. Chaukhambha Sanskrit series office Varanasi. 2008; 50/167 p. 397
9. Chunekar K. Bakuchi, haritaki varga. Bhavprakash nighantu. 2013(edition). Chaukhambha bharati academy, Varanasi p.119.
10. Gupta K. A., kushthashvitrakrimi-nidanam. Upadhyaya Y.N. (ed.). Astanghrdayam, vidyotinitika. Chaukhambha Prakashan Varanasi. 2009; 14/39 p.533.
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Urkude et al. European Journal of Biomedical and Pharmaceutical Sciences
HOLISTIC MANAGEMENT OF DADRU KUSHTHA W. S. R. TO DERMATOPHYTOSIS -
A CASE STUDY
1*Urkude G. D. (Ph.D Scholar-Swasthvrutta),
2Nistane R. R. (MD Swasthvrutta and Yog)
3Rathod S. P. (MD
Kaychikitsaa) and 3Khatri A. G. (MD Kaychikitsaa)
1Assistant Professor, Department of Swasthvrutta and Yog ASPM Ayurved College, Buldhana. C/o Kalawati D.
Urkude Budhwari peth Umred, District: Nagpur Mharashtra. 2Ayurved Consultant, Aishwarya Ayurved Pratishthan, Umred, C/o Kalawati D. Urkude Budhwari peth Umred,
District: Nagpur Mharashtra. 3Assistant Professor, Department of Kaychikitsa K. R. Pandav Ayurvedic Medical College.
3Ayurved Consultant, Ojus Ayurved, Pratapnagar Nagpur.
Article Received on 27/07/2019 Article Revised on 16/08/2019 Article Accepted on 07/09/2019
INTRODUCTION
In present era, Ayurvedic medicines are often used as a
effective measure for treating chronic and life style
related diseases.[1]
Skin is a vital sense organ of our body
which perform various physiological function such as
thermoregulation, conservation & excretion of fluid and
it also prevents invading pathogens. Skin is the external
organ that protects against mechanical trauma, ultraviolet
light & infection.[2]
In Ayurveda, Charaka[3]
has
explained Dadru kushta under Kshudra Kushta while,
Sushruta has mentioned it under Mahakushta. Acharya
Dalhana has mentioned its two types as Sita and Asita.
Dadru can be diagnosed by symptoms like Pidika,
Kandu, Raga, Mandala, Visarpini[4]
This condition can
be correlated with dermatophytosis, caused by a group of
keratinophilic fungi, dermatophytes.
It is common in
India due to its tropical climates. Adults young and
middle aged are typically affected. Predisposing factors
includes obesity, diabetes mellitus, sweating, thick
clothing in humid atmosphere and sharing personal
articles like towels. As per site affection dermatophytosis
is categorized tinea capitis (scalp), tinea corporis (trunk),
tinea cruris (limb), tinea pedis (feet) & tinea barbae.[5]
Here in patient previously received treatment as
Antifungal therapy (both systemic and topical) from
eminent dermatologist for about 3 months was treated
with complex Ayurvedic modalities like krumighna
chikitsa followed by shaman chikitsa and local
application. A substantial reduction in pruritus and
improvement in skin lesion were observed after 30 days.
The improvement was observable through follow up
photographs [fig.1-3]
CASE REPORT
A 12 year old male child diagnosed previously as
Dermatophytosis via dermatologist presented in
outpatient department. of Aishwarya Ayurved clinic
Umred, District-Nagpur, Maharashtra, India with
complain of Kandu( itching), erythomatous papules, tiny
vesicles and pustules around the scaly variably
pigmented patch (Mandal, Rag, Atasi pushpabh varna)
(Figure 1,2,3 before) since 6 months these symptoms
were primarily reduced with antifungal therapy of
dermatologist but after 3 month treatment swelling over
body was seen along with weight gain. So, patient visited
for Ayurvedic treatment.
ABSTRACT
The skin is vital external organ that provides protection against mechanical trauma, ultraviolet light & infection.
Superficial fungal infections of skin are localized to stratum corneum caused by Trichophyton rubrum &
Pityrosporam. The skin conditions caused by these fungal infection are labeled as per the region involved
(Dermatophytosis). Consciousness regarding skin diseases is increased as it may create physical or psychological
problems in individual. It has resemblance with skin condition Dadru (a type of Kshudra Kushtha) explained in
Ayurvedic classics. Presently used treatment modalities are unsatisfactory, with side effects & has chances of
recurrence. A case which has received modern treatment for about 3-4 months was treated successfully with
Ayurvedic medicinal & life style interventions.
KEYWORDS: Ayurved, Dadru, Kshudra Kushtha, Dermatophytosis,tinea corposis, tinea Pedis).
*Corresponding Author: Dr. Urkude G. D.
Assistant Professor, Department of Swasthvrutta and Yog ASPM Ayurved College, Buldhana. C/o Kalawati D. Urkude Budhwari peth Umred,
District: Nagpur Mharashtra. Email id: [email protected]
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CLINICAL FINDING
General examination
Patient was having good general condition and vitals
were normal. The appetite of the patient was altered and
reduced. The bowel and bladder habits were regular.
Patient was having regular sleep pattern.
Prakruti:- Kapha Pitta predominant
Local Examination
Cutaneous examination revealed formation of active
margin of erythematous papule tiny vesicle and pustules
around scaly pigmented patch. The sites of such lesions
(each measuring 3cm*2cm) were at upper forearm, chest
region, thigh region (figure 1-3). No sign of bleed,
swelling and discharge.
Investigation
No biopsy was done.
Case conception and selection of Ayurvedic treatment
Though patient was receiving treatment of dermatologist
since 3 month improvement was not satisfactory and
lesions were spreading over the other body parts, patient
became aware of disadvantages of treatment from other
sources and patient relatives chosen Ayurvedic
intervention for his condition. There was no established
Ayurvedic treatment for dermatophytosis we explained
the patient relative about uncertainty of the treatment.
On observing the pattern of lesions we tried to diagnosed
it with Ayurvedic perspective, Dadru is clinical
condition described in Ayurvedic text book which
resembles Dermatophytosis. The Ayurvedic perspective
of this particular case presenting with itching and
formation of erythomatous, vesicular, scaly & pigmented
lesion. Itching is a suggestive of kapha dominancy and
erythomatous patch with vesicles and pustules is
suggestive of Pitta dominance, on the basis of
symptomatology the disease can be equated with Pitta
Kapha Kushta. The etiology (Nidan) of Kushta is Dushi
Visha usually results due to exposure of certain
environmental factors or due to consumption of
incompatible foods which is responsible for Rasa dhatu,
Rakta dhatu, Rasavaha strotas and Raktavaha strotas
which is responsible for kapha and pitta dushti. In this
patient initially Kapha dushti was started as a itchy
lesion over forearm. This was suggestive of Rasa Dhatu
and Rasavaha Strotas Dushti. The itching was followed
by formation of erythematous patch (Rag) tiny vesicles
(Mandal), pustules (Pidika). This symtomatology was
suggestive of association of Pitta Dosha, Rakta Dhatu &
Raktavaha Strotas Dushti. Specifically etiological factors
(Nidan) founding patient in Ayurvedic perspective were
Ratrau dadhi sevan (eating curd at night) [6]
and Kapha
predominant diet such as milk products.
The principle of managment in different stages of Kushta
(skin diseases) includes Shodhan Karma (therapeutic
emesis – Vaman) purgation – Virechan etc., shaman
chikitsa (internal administration of drugs) and tropical
applications.[7]
Acharya vagbhata considered krumi as
predisposing factor for Kushta formation[8]
based on the
Nidan Sevan ( dietary factors) these patient was probably
susceptible for krumi so, we considered Krumi Chikitsa
before starting Vyadhi Viparit Chikitsa. Considering the
involvement of Dosha and Dushya (pathognomonic
factors) and analysis of causative factors (Hetu) of the
disease, patient was recommended a comprehensive
Ayurvedic modalities consisting of Ahara, Aushadha,
Vihara. The drug intervened were having Pitta
Kaphaghna properties along with Krumighna,
Kandughna and Kushtaghna properties. These drug were
prescribed at different stages in the case. The patient was
advised to report at an interval of 15 days. Medicines
received is mentioned. [Table : 2].
Follow up & Outcomes
The photos of affected areas were taken at the time of
initiation of treatment and subsequently on visit (every
30 days). Observations were noted subsequently. The
consecutive pictures were taken after follow up and
compared with previous photos before intervention. This
showed considerable improvement in the skin lesions
following the therapy as compared to pretreatment status.
During treatment no adverse effect of therapy was noted
and no relapse even after stopping medicines for next 15
days.
Table 1: Time line of the case.
Sr. Dates Related History
1. August 2017 Almost Normal
2. September 2017 Presented with symptoms mentioned
(Dermatophytosis)
3. September 2017 Started treatment from Dermatologists and
continued for 3 months
4. 15 December 2017 Treatment at Aishwarya Ayurved Clinic started
5. 20 March 2018 Treatment Concluded and medicine stopped.
6. 21 March to until now Observation for recurrence without medicine.
No recurrence seen.
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Urkude et al. European Journal of Biomedical and Pharmaceutical Sciences
Table 2: Summary of follow up.
Sr. Dates Symptoms Intervention
1 15 Dec 2017
a. Kandu ( itching),
b. Erythomatous papules (Rag)
c. Tiny vesicles (Mandal)
d. Pustules (Peetika)
i. Krumikuthar Ras 250 mg Bd postmeal
ii. Cap Purodil 500 mg Bd postmeal
iii. Cutis Oil local application
2
2 Jan 2018
a. Kandu ( itching),
b. Erythomatous papules (Rag)
c. Tiny vesicles (Mandal)
i. Krumikuthar Ras 250 mg Bd postmeal
ii. Kutki (10 gm) + Manjishta (20 gm) + Sariva (20 gm) +
Vidang (20 gm) + Triphala (20 gm) + Musta (20 gm)
Quath 20 ml Bd 2-3 hrs before meal
iii. Cutis Oil local application
3 20 Jan 2018 Tiny vesicles (Mandal)
i. Khadirarishta 10 ml Bd postmeal
ii. Vidangarishtha 10 ml Bd postmeal
iii. Cutis Oil local application
4 25 Feb 2018 Tiny vesicles (Mandal) i. Mahamanjishthadi Kadha 10 ml Bd Postmeal
ii. Cutis Oil local application
5 20Mar 2018 Tiny vesicles (Mandal) i. Mahamanjishthadi Kadha 10 ml Bd Postmeal
ii. Cutis Oil local application
Table 3 Grades (Improvement).
Sr Symptom 15/12/17 2/01/18 20/01/18 25/02/18 20/03/18
1 Kandu (itching), +++ + absent absent absent
2 Erythomatous papules (Rag) ++ + absent absent absent
3 Tiny vesicles (Mandal) +++ ++ + + minimal
4 Pustules (Peetika) + absent absent absent absent
Before After
Figure 1.
Before After
Figure 2.
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Urkude et al. European Journal of Biomedical and Pharmaceutical Sciences
Before After
Figure 3.
DISCUSSIONS
Dadru Kushtha is a kind of skin condition mentioned in
Ayurveda under the heading of Kshudra Kushtha. The
pratyatmak lakshana (Classical sign) of As per Charaka
Dadru is Pitta Kapha dominant Kushtha associated with
formation of erythomatous, vesicular, scaly & pigmented
lesion with itching.[9]
General management of all types of
Kushtha consists of Samshodhana (Purification therapy)
followed by Samshamana (Internal & external
administration of drugs).[10]
Nidan Parivarjana by
intervention of dietary and lifestyle management.
Correlation of dermatophytosis is done with Dadru on
the basis of symptoms similarity. Dermatophytes are
among the common fungal agents implicated in
superficial skin infections worldwide. In hot and humid
climates of tropical and subtropical regions, the
incidence of these pathogens is higher.[11]
In the
presenting case, though the residence of case belongs to
tropical region Chandrapur in Maharashtra (where
climate is hot due to coalmines). The immune response
to infection by dermatophytes ranges from a nonspecific
host mechanism to a humoral and cell-mediated immune
response.[12]
The currently accepted view is that a cell-
mediated immune response is responsible for the control
of dermatophytosis. The current conventional treatment
involves antifungal medication. Ayurvedic principle have
shown potential for the use in non communicable and life
style diseases. These are convenient safe, and less
expensive as compare to conventional method of
treatment [13]
. In this case medications, diet and life style
modification were chosen [Table 2] on the basis of Nidan
( causative factors), dominant Doshas (Pitta, Kapha) and
Vyadhi (natute of the disease). Formulations having
Virechan, Pittakaphaghna, Kandughna, Kushthaghna
and Krumighna effects were used. Khadirarishtha is one
of the preparation having above mentioned properties.[14]
Cutis oil is market preparation (proprietary) given for
local application. Tab Purodil, market preparation
(proprietary) used as a blood purifier. Vidangarishta is
used specially for achieving krumighna property.[15]
Other drug used is Mahamanjishthadi kwath as
Rakshodhaka & Prasadak.[16]
Contents and details of
medications used are given in table 3.
The pattern of treatment used in this case may be applied
to the similar case too. However depending on conditions
further preparation from Ayurvedic test can be tried to
assess further role of Ayurveda.
CONCLUSION
Dermatophytosis is a common condition seen in all age
groups. The conventional treatment option available are
not satisfactory and have systemic side effects, so the
observation of this case study endorses a step towards
practicing Ayurvedic intervention in dermatophytosis.
Acknowledgement: We are thankful to participant for
providing informed consent to published the result of the
study. Also Vd. Anant Dharmadhikari & Vd. Anand
Tembhurnikar Sir for there guidance.
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Nidansthan, chapter 14 verse 4-5, edited by Paradkar
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Urkude et al. European Journal of Biomedical and Pharmaceutical Sciences
H. S., Chaukhambha Orientalia Varanasi 1st ed.,
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Chikitsasthan, chapter 19 verse 92-94, edited by
Paradkar H. S., Chaukhambha Orientalia Varanasi
1st ed., 718.
11. Bhatia V., Sharma P. Epidemiological studies on
Dermatophytosis in human patients in Himachal
Pradesh, India. Springer Plus, 2014, 3: 314.
12. Sahoo A., Mahajan R., Management of Tinea
corporis, Tinea Cruris & Tinea Pedis: A
comprehensive review. Indian Dermatology online
journal, 2016.
13. Pandey M. M., Rastogi S, Rawat AK. Indian
Traditional Ayurvedic System of Medicine and
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14. Ayurved Sarsangraha, 1st edition 2000, Baidynath
Bhavan Nagpur, Kadambary printers, reprint, 2004;
640-641.
15. Ayurved Sarsangraha, 1st edition 2000, Baidynath
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International Journal of Applied Ayurved Research ISSN: 2347- 6362
COMPARATIVE STUDY OF EFFICACY OF KSHIRBALA TAILA
NASYA AND CERVICAL TRACTION IN THE MANAGEMENT OF
MANYASTAMBHA (CERVICAL SPONDYLOSIS) 1 Turankar Aditya,
2 Rathod Suraj,
3 Ganvir Rakesh,
4 Vyas Prathamesh
1Assistant Professor, Dept of Panchakarma,Shri KR Pandav Ayurveda College & Hospital,
Bahadura, Nagpur. 2Assistant Professor, Dept of Kayachikitsa, Shri KR Pandav Ayurveda College &
Hospital,Bahadura,Nagpur. 3Assistant Professor, Dept of Rasshashtrra,Shri KR Pandav Ayurveda College & Hospital,
Bahadura,Nagpur. 4Assistant Professor, Dept of Panchakarma, M.S. Ayurveda College & Hospital, Gondia.
ABSTRACT
Background: Cervical spondylosis is the most common progressive disorder in the aging
cervical spine. Manyastambha is coming under one of the Vataja nanatmaja vikara. Nasya
Karma, being the treatment of choice in Urdhvajatrugata Vata Vyadhis, is adopted in the
management of Manyastambha. Aim & Objectives: Aim: To study comparative efficacy of
Kshirbala Taila Nasya and Cervical Traction in the management of Manyastambha.
(Cervical Spondylosis) Objectives: To study the effect of Kshirbala Taila Nasya and
Cervical Traction in Manyastambha. To find out the reduction in cardinal signs of
Manyastambha viz- Stambha (Stiffness), ruka (pain) by Nasya Karma using Kshirbala
Taila. Materials & Methods: It is a comparative study of Nasya Karma using Kshirbala
Taila and Cervical Traction in the management of Manyastambha. Total 30 patients were
selected in each group and group A were subjected to Nasya Karma and Group B were
subjected to Cervical Traction. Conclusion: Cervical Spondylosis is chronic disorder need
the skilful managements. On day 14 the percentage of relief was seen more as compare to
Day 30. In both group there was relief in both symptoms of Manyastambha i.e. Stambha
(Stiffness) & Ruka (pain) and it was statistically found significant.
Keywords:Manyastambha, Cervical Traction, Nasya,Ruka, Stambha.
INTRODUCTION: Manyastambha
derived from two different words Manya
and Stambha.1
Manyastambha is coming
under one of the Vataja nanatmaja
vikara.2
Manya Shoola, Manyastambha are
the main symptoms.3
The etiological
factors responsible for the Manyastambha
have been mentioned by Sushrut.
According to him sleep in day time,
leaning or sleeping on an uneven place,
constantly gazing upward and Avarana of
Vayu by Kapha lead to the disease
Manyastambha.4 Cervical spondylosis is
the most common progressive disorder in
the aging cervical spine. Cervical
spondylosis is degeneration of inter-
vertebral disc, with its protrusion and bony
overgrowth of adjacent vertebrae causing
compression of roots, cord or both. It
results from the process of degeneration of
the intervertebral discs and facet joints of
the cervical spine.5 Nasya Karma, being
the treatment of choice in Urdhvajatrugata
Vata Vyadhis, is adopted in the
management of Manyastambha.6,7
In
Conservative management of Cervical
Spondylosis, Cervical Traction is
indicated. Cervical Traction is the
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modality of choice for many neck and
cervical dysfunctions.8 Cervical Traction is
accomplished by pulling the patient’s head
in a cephalad direction, in other words,
away from the trunk. Cervical Traction has
also been shown to relieve headaches and
pain due to general soft tissue stiffness.9
Thus, this study has undertaken this study
to evaluate the therapeutic efficacy of
Nasya Karma and Cervical Traction in
Manyastambha.
AIM & OBJECTIVES:
AIM:To study comparative efficacy of
Kshirbala Taila Nasya and Cervical
Traction in the management of
Manyastambha. (Cervical Spondylosis)
OBJECTIVES:
1. To study the effect of Kshirbala Taila
Nasya and Cervical Traction in
Manyastambha.
2. To find out the reduction in cardinal
signs of Manyastambha viz- Stambha
(Stiffness), ruka (pain) by Nasya
Karma using Kshirbala Taila.
3. To find the reduction in cardinal signs
of Manyastambha viz- Stambha
(Stiffness), ruka (pain) by cervical
traction.
4. To compare the effect of Nasya Karma
with Kshirbala Taila and Cervical
Traction in Manyastambha.
MATERIALS & METHODS:
This study has been conducted at
Mahadevrao Shivankar Ayurvedic Medical
College, Hospital and Research Institute,
Gondia. An institutional ethics approval
been taken before initiation of the study. It
is a comparative study of Nasya Karma
using Kshirbala Taila and Cervical
Traction in the management of
Manyastambha. Total 30 patients were
selected in each group and group A were
subjected to Nasya Karma and Group B
were subjected to Cervical Traction.
Group A – Nasya Karma for 2 weeks (14
days)
Group B - Cervical Traction for 2 weeks
(14 days).
Total duration of study was for 30 days.
Follow ups were taken on Day 21 and Day
30.
Inclusion Criteria:
Patients having the signs and symptoms of
Manyastambha between the age group of
20 -70 years of either sex.
1. Patients fit for cervical traction with
Limitation of Cervical spine range of
motion, Cervical Spondylosis, Cervical
Radiculopathy.Patient willing for the
treatment of Nasya and Nasyaahraya.
Exclusion criteria:
1. Patients with major disorders that is
traumatic, infective and neoplastic
conditions of spine, Congenital
anomalies involving the Cervical-
spine, Viral infections like Polio
Myelitis, Transverse Myelitis,
Bacterial infections like TB spine,
Demyelinating diseases, Fibromyalgia,
Motor neuron diseases that interfere
with the course of treatment were
excluded from the study. Patients
undergoing other modalities of
treatment for Manyastambha were
excluded.
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Table No.1 Group management:
Particular Group A Group B
Treatment given Nasya Cervical Traction
Purvakarma Snehana and Mrudu
Svedana of Griva Pradesh,
Mukha Pradesh.
Ornaments removed from neck region
and patient is lie in supine position.
Pradhanakarma Kshirbala Taila Nasya Cervical Traction with tractive force -
1/10th
body weight of patient.
Paschata Karma Gandusha(Hot water) The patient is lied in lateral position for 5
minutes
Pathya-Apathya Advised as per work and
food habits
Advised to patient as per work and food
habits.
Standard Operative Procedure of Nasya
- Group (A)
Purvakarma: Bahya Snehana by
application of Tila Tail in Manyapradesh,
Mukha Pradesh and Mrudu Svedana in the
form Tapa Sveda by cotton cloth squeezed
after dipped in hot water were done.
Pradhana Karma:
Nasya were given between 4- 6 pm.
Patient is lied down in comfortable
supine position on Table and head low
position were made with the help of
pillow. Head is neither be excessively
flexed or extended. A range of 30° to
60° extension is made during
administration of Nasya drops.
Administration of Kshirbala Taila
Nasya 8 drops (0.4ml) in each Nostrils.
The palms and sole of the patient are
rubbed well with hands.
Patient is asked to lie down in same
position for 100 matrakala and spit out
the secretions reaching the mouth and
not to swallow it.
Patient were observed for Nasya
Samyakadi Lakshana.
Paschat Karma:
Mrudu Abhyanga and Tapa svedana
were done of the Manya and Mukha
Pradesh.
Gandusha- Gandusha were done with
hot water.
Patient is advised to avoid polluted air,
bath, excitement and contraindicated
food.
Assessment Criteria
1) Stambha (Stiffness in the Neck )
Movements
Grade
Freely movable 0
Movable with pain 1
Movable with pain to lesser range 2
Partial or no movement possible 3
2) Ruka (Pain) Table no.2 Type of Pain
Type of Pain Score Grade
Absent 0 0
Mild Pain 1 - 4 1
Moderate Pain 5 - 8 2
Severe Pain 9 - 10 3
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Table no.3 Numeric Rating Scale :
(patient is asked to enter the number in the column “0-10 Numeric Pain Intensity scale”)
0 1 2 3 4 5 6 7 8 9 10
No
pain
Worst pain
imaginable
OBSERVATION & RESULTS:
Specially designed Case Report Form
(CRF) was used to fill the all basic as well
as clinical information of the patients.
Patients were examined prior to the start of
treatment with respect to the Performa.
Table No.4 Gender Wise Distribution of Patient of Manyastambha:
Sex Group-A Group-B Total Percentage
Male 21 17 38 63.33
Female 09 13 22 36.67
In this study, totally 38 [63.33%] were
male & 22[36.67%] were female while
more male was recruited in Group-A it
may be due random selection of patients.
Table No.5 Age Wise Distribution of Patient of Manyastambha:
Sr.
No.
Age
group
Group-A Group-B Total
No. of
Patient %
No. of
Patient %
No. of
Patients Percentage %
1 20-30 0 0.00 1 3.33 1 1.67
2 31-40 4 13.33 4 13.33 8 13.33
3 41-50 9 30.00 12 40.00 21 35.00
4 51-60 10 33.33 6 20.00 16 26.67
5 61-70 7 23.33 7 23.33 14 23.33
Total 30 100.00 30 100.00 60 100.00
Graph 1. Age Wise Distribution of Patient of Manyastambha:
CLINICAL OBSERVATIONS:
0
5
10
15
20
25
Group-A Group-B Total
No.o
f P
atie
nts
Age Group
20-30
31-40
41-50
51-60
61-70
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Table No.6 Percentage of Relief (Subjective Criteria) in Each Symptom of 60 Patients of
Manyastambha:
Sr.
No
Symptoms Group-A Group-B
D14 D21 D30 D14 D21 D30
1 Stambha(Stiffness) 66.10 33.90 40.68 69.39 48.98 30.61
2 Ruka (Pain ) 68.42 50.00 51.32 64.47 57.89 48.68
Graph 2: Showing follow up wise percentage of relief in Group-A
Graph 3: Showing follow up wise percentage of relief in Group-B
Friedman Test (Repeated measure non parametric tests) for subjective criteria of
Manyastambha in Group-A:
1. Stambha(Stiffness) Table No.7
Stambha
(Stiffness) D0 D14 D21 D30
Fr
Statistics
P Value
Sum of Ranks 108.5 45 76.5 70
55.89 <0.001 Mean SD 1.960.66 0.660.60 1.30.53 1.160.64
Median 2 1 1 1
In Symptom, Stambha(Stiffness) on every
follow up i.e. Day 14,21 and 30 days it
was observed that there is significant
difference of intervention statistically as p
value obtained was <0.001 which is
considered as highly significant. Further
comparison done within each follow up by
Dunn’s multiple comparisons test.
66
.1
33
.9
40.6
8
68
.42
50
51
.32
D14 D21 D30
Stambha(Stiffness) Ruka (Pain )
69.3
9
48.9
8
30.6
1
64
.47
57
.89
48
.68
D1 4 D2 1 D3 0
Stambha(Stiffness) Ruka (Pain )
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Table No.7a Dunn’s multiple comparisons test
The effect was seen significantly different
as compare to Day 0 and Day 14, Day 0
and Day 21, the difference is also
significant on day 0 and 30, day 14 and
Day 21as p value obtained was <0.01
which shows statistically highly
significant. There was no difference
observed between Day 14 and Day 30,
Day 21 and Day 30.
1. Ruka(Pain) Table No.8
Ruka(Pain) D0 D14 D21 D30
Fr
Statistics
P Value
Sum of Ranks 114.5 50 70 65.5
56.33 <0.001 Mean SD 2.530.57 0.80.71 1.260.63 1.230.56
Median 3 1 1 1
In Symptom Ruka(Pain) on every
follow up i.e Day 14,21 and 30 days it was
observed that there is significant difference
of intervention statistically as p value
obtained was <0.001 which is considered
as highly significant. Further comparison
done within each follow up by Dunn’s
multiple comparisons test.
Table No.8a Dunn’s multiple comparisons test
The effect was seen significantly different
as compare to Day 0 and Day 14, Day 0
and Day 21, the difference is also
significant on day 0 and 30, as p value
obtained was <0.001 which shows
statistically highly significant. There was
no difference observed between Day 14
and Day 21, Day 14 and Day 30, Day 21
and Day 30.
Sr.no Comparison Rank sum
difference
p value Result
1 D 0 vs D 14 63.5 <0.001 ***
2 D 0 vs D 21 32.0 < 0.01 **
3 D 0 vs D 30 38.5 <0.001 ***
4 D 14 vs D 21 -31.5 < 0.01 **
5 D 14 vs D 30 -25.0 >0.05 NS
6 D 21 vs D 30 6.5 >0.01 NS
Sr.no Comparison Rank sum
difference
p value Result
1 D 0 vs D 14 64.5 <0.001 ***
2 D 0 vs D 21 44.5 < 0.001 ***
3 D 0 vs D 30 49.0 <0.001 ***
4 D 14 vs D 21 -20. >0.05 NS
5 D 14 vs D 30 -15.5 >0.05 NS
6 D 21 vs D 30 4.5 >0.05 NS
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Friedman Test (Repeated measure non parametric tests) for subjective criteria of
Manyastambha in Group-B:
1. Stambha(Stiffness) Table No.9
Stambha
(Stiffness) D0 D14 D21 D30
Fr
Statistics
P
Value
Sum of Ranks 103 49.5 67.5 80
39.53 <0.001 Mean SD 1.630.55 0.50.57 0.830.74 1.130.57
Median 2 0 1 1
In Symptom, Stambha(Stiffness) on every
follow up i.e Day 14,21 and 30 days it was
observed that there is significant difference
of intervention statistically as p value
obtained was <0.001 which is considered
as highly significant. Further comparison
done within each follow up by Dunn’s
multiple comparisons test.
Table No.9a Dunn’s multiple comparisons test
The effect was seen significantly different
as compare to Day 0 and Day 14, Day 0
and Day 21, the difference was not found
significant on day 0 and 30, day 14 and
Day 21as p value obtained was >0.05
which shows statistically not significant.
There was no difference observed between
Day 21and Day 30.
2. Ruka(Pain) Table No.10
Ruka(Pain) D0 D14 D21 D30
Fr
Statistics
P Value
Sum of Ranks 115 53 62 70
53.60 <0.001 Mean SD 2.530.57 0.90.54 1.060.69 1.30.59
Median 3 1 1 1
In Symptom Ruka(Pain) on every
follow up i.e. Day 14,21 and 30 days it
was observed that there is significant
difference of intervention statistically as p
value obtained was <0.001 which is
considered as highly significant. Further
comparison done within each follow up by
Dunn’s multiple comparisons test.
Table No.10a. Dunn’s multiple comparisons test
Sr.no Comparison Rank sum
difference
p value Result
1 D 0 vs D 14 53.5 <0.001 ***
2 D 0 vs D 21 35.5 < 0.01 **
3 D 0 vs D 30 23.0 >0.05 NS
4 D 14 vs D 21 -18.0 >0.05 NS
5 D 14 vs D 30 -30.5 <0.05 *
6 D 21 vs D 30 -12.5 >0.05 NS
Sr.no Comparison Rank sum
difference
p value Result
1 D 0 vs D 14 62 < 0.001 ***
2 D 0 vs D 21 53 < 0.001 ***
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The effect was seen significantly
different as compare to Day 0 and Day 14,
Day 0 and Day 21,the difference is also
significant on day 0 and day 30, as p value
obtained was <0.001 which shows
statistically highly significant. There was
no difference observed between Day 14
and Day 21, Day 14 and Day 30, Day 21
and Day 30.
Table No.11 Showing Comparison between Two Group w.r.t Symptoms of 60 Patients
of Manyastambha By Mann-Whitney ‘U’ Test
No Symptoms Mean ± SD Statistics P Value
Gr-A Gr-B U’ U
1 Stambha(Stiffness) 0.80±0.66 0.50±0.73 534 366 0.2108
2 Ruka (Pain ) 1.30±0.70 1.23±0.77 464.5 435.5 0.8377
The Difference between score of both
Groups compared by ‘Mann-Whitney U-
Test’. It was found that the sum of rank of
Group-B for the symptom Stambha U’
statistics was 534, Test statistic (U) was
366, where the test statistic U not lies
between Population Mean 1.96 SD which
was not significant statistically. (p>0.05)
Therefore the difference between
Symptom Score of Stambha of Group-A &
Group - B is statistically not significant, so
therefore we can conclude that in the
symptom Stambha intervention of both
groups having equal effect.
In symptoms like Ruka ‘U’ statistics was
464.5 and the test statistics U was 435.5
which was not lies between Population
Mean 1.96 SD which was not significant
statistically. (p>0.05).
Therefore, the difference between
Symptom Score of Ruka of Group-A &
Group - B is statistically not significant, so
therefore we can conclude that in the
symptom Stambha intervention of both
groups having equal effect. After
comparison of both Group there was no
significant result was noted in both group
as p value was not significant in symptoms
of Manyastambha.
Table No.12Total Effect of therapy in 60 Patients of Manyastambha :
Sr.
No
Effect of Therapy
No. of Patients Percentage %
Gr-A Gr-B Total Gr-A Gr-B Total
A. Complete Relief
(100% relief) 03 00 03 10.0 0.0 5.0
B. Marked Improvement
>75% to <90% relief 08 01 09 26.7 3.3 15.0
C. Moderate Improvement
>50% to 75% relief 12 25 37 40.0 83.3 61.7
D. Mild Improvement
>25% to <50% relief 05 03 08 16.7 10.0 13.3
E. Unchanged
<25% relief 02 01 03 6.7 3.3 5.0
3 D 0 vs D 30 45 < 0.001 ***
4 D 14 vs D 21 -9 >0.05 NS
5 D 14 vs D 30 -17 >0.05 NS
6 D 21 vs D 30 -8 >0.05 NS
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In Group-A, 03 (10%) patients completely
improved, 08(26.7%) patients were
marked improved, 12(40%) patient were
having moderate improvement, 05(16.7%)
were having mild improvement while
02(6.7%) patient were having no
improvement.
In Group-B, no patients completely
improved, single patient marked improved,
25(83.3%) patient were having moderate
improvement, 03(10%) were having mild
improvement while 01(3.3%) patient was
no improvement.
Totally, 03 (5%) patients completely
improved, 09 (15%) patients were marked
improved, 37(61.7%) patient were having
moderate improvement, 08(13.3%) were
having mild improvement while 03(5%)
patient were having no improvement.
DISCUSSION:
Mode of Action of intervention:
Nasya Karma, being the treatment of
choice in Urdhvajatrugata Vata Vyadhis,
is adopted in the management of
Manyastambha. Specific posture during
Nasya karma, like the lowering of the
head, fomentation of face seems to have an
impact on blood circulation of the head
and face. According to Sushruta, manya is
a marma existing in neck on either side of
trachea which likely corresponds to the
carotid sinus of neck on the bifurcation of
common carotid artery. Drug administered
through nose -the doorway to Shira
reaches the Shringataka marma of Head
(Shira), which is a siramarma and formed
by the siras of nose, eyes, kantha and
shrotra the drug spreads by the same route
scratches the morbid Doshas of
Urdhwajatru and extracts them from the
Uttamanga.
Traction is commonly used in the cervical
spine to relieve pressure on the cervical
nerve roots in patients with disc
herniations, degenerative disc disease and
spinal stenosis. Cervical traction is done
either lying flat or sitting and uses weights
to add distraction pressure to the neck.
Cervical traction is used for a number of
cervical spine injuries including cervical
herniated nucleus pulposus, radiculopathy,
strains, zygapophyseal joint syndromes
and myofascial pain. Pain relief may occur
through one of several mechanisms,
including: rest through immobilization and
support of the head, distraction of the
zygapophyseal joints and associated
improved nutrition to the articular
cartilage, tightening of the longitudinal
ligament and decreasing intradiscal
pressure (both of which press a bulging
disc more centrally), relieving nerve root
pressure via increased foraminal diameter,
improving head posture, and elongating
muscles to improve blood flow and reduce
spasm.
CONCLUSION:
Cervical Spondylosis is chronic disorder
need the skilful managements. It was
observed that as the treatment finishes the
effect of intervention remains and as the
duration increase after the treatment the
symptoms remerges. On day 14 the
percentage of relief was seen more as
compare to Day 30. In both group there
was relief in both symptoms of
Manyastambh i.e. Stambha (Stiffness) &
Ruka (pain) and it was statistically found
significant. After comparison of both
Group there was no significant result was
noted in both group as p value was not
significant in symptoms of
Manyastambha. Study can be done taking
Nasya along with any medicine further on
more patients. Nasya and physiotherapy
can help to improve further.
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REFERENCES:
1. Amarkosha – Amarsingh, Nirmaya
Sagar Press Bombay, 6th edition 1944,
Chaukhambha Sanskrita Series 1st
edition Varanasi, 1970.
2. Prof. Srikantha Murthy edited
Ashtanga Hridayam Nidanasthanam
chapter 15th
23rd
sloka,Reprint 2010,Chaukambha
Krishnadas Academy , Varanasi, pg
no. 152
3. Acharya Prayavat Shrma edited
Susrutha Samhitha Nidanasthana
Dalhana teeka 1st chapter 67th sloka.
Reprint2007. Chaukambha
Orientalia.Varanasi. Pg no.264.
4. Acharya P.V.Sharma edited Susrutha
Samhita Nidanasthana Dalhana Teeka
1st chapter 67th
sloka.Reprint2007.Chaukambha
Orientalia. Varanasi.Pg no.267.
5. Siddhartha.N.Shah,API text book of
Medicine 29th Chapter 7th edition
2003 Pg no.885-88.
6. Bhavmishra, Bhavprakasha,
Purvakhanda, 5/59, edited by prof K.
R. shikantha murthy, vol 1, Krishnadas
Academy, Varanasi.p.272
7. Shukla V, editor, (2nd ed.). Charaka
Samhita of Charaka, Siddhistana:
Chapter 2, Verse 22. Varanasi:
Chowkhambha Sanskrit Series, 2002;
895
8. http://www.neurosurgerypa.com/proce
dures/Cervicaltraction.html cited on
17.02.2020
9. Wieslander, L., and Douglas L. Buck.
"Physiologic recovery after cervical
traction therapy." American journal of
orthodontics 66.3 (1974): 294-301.
Corresponding Author:
Dr.Aditya Turankar,Assistant Professor,
Dept of Panchakarma, Shri KR Pandav
Ayurveda College & Hospital, Bahadura,
Nagpur.
Email: [email protected]
Source of support: Nil Conflict of interest:
None Declared
Cite this Article as :[ Turankar Aditya et al :
Comparative Study of Efficacy of Kshirbala Taila
Nasya and Cervical Traction in the Management of
Manyastambha (Cervical Spondylosis)
]www.ijaar.in : IJAAR VOLUME IV ISSUE
VI JAN –FEB 2020 Page No: 572-581
RESEARCH ARTICLE Rakesh et.al / IJIPSR / 7 (7), 2019, 60-68
Department of Ayurvedic Science ISSN (online) 2347-2154
DOI: 10.21276/IJIPSR.2019.07.07.838
Available online: www.ijipsr.com July Issue 60
STUDY OF ANALYTICAL PROFILES OF MADHUMALINI
VASANTA
1Dr. Rakesh Ganvir*,
2Dr. Swati Dongre,
3Dr. Suraj P. Rathod,
4Dr. Kavita Deshmukh
1Asst. Professor, Dept of Rasshastra, Shri K R Pandav Ayurved College and Hospital, Nagpur, INDIA 2Asst professor Dept of Rasashastra & Bhaishajya, Kalpana Shree Ayurved College Nagpur, INDIA
3Assistant Professor, Department of Kayachikitsa, Shri K R Pandav Ayurved College & Hospital
Bahadura, Nagpur, INDIA 4Associate Professor,SSAM Hadapsar Pune, INDIA
Corresponding Author:
Dr. Rakesh Ganvir
Asst.Professor, Dept of Rasshastra
Shri K R Pandav Ayurved College and Hospital, Nagpur, INDIA
Email: [email protected]
Phone: +91-8237691101
International Journal of Innovative
Pharmaceutical Sciences and Research www.ijipsr.com
Abstract
Rasaushadhihas an edge over herbal medicines due to quicker mode of action, least dosage and
easy administration. Vasanta Malati Rasa Kalpais herbo-metallic compounds which come under
subheading of Kharaliya-Rasayana of Rasaushadhis. Madhumalini Vasanta as per
Rasachandanshu is type of Vasanta Kalpas. In Madhumalini Vasanta, Hingula is a main
ingredient. Preparation of compound and its efficacy has been mentioned in several classics. The
present study was executed to establish a Analytical profile for this unique formulation which can
be used further for drug standardization. The study involved preparation of Madhumalini Vasanta
as per Rasachandanshu method. The tablets were evaluated for Organoleptic tests, Physical test
analysis, Chemical test analysis like Total ash value, Acid Insoluble ash, Moisture Content, pH
Value, Thin Layer Chromatography (TLC), X-Ray Diffraction, Scanning Electron Microscope
with EDAX, it was concluded that the absorption capacity of Hingula decreases after each
Bhavana. This study can serve the need or the characterization of MadhumaliniVasanta.
Keywords: MadhumaliniVasanta., Rasaushadhihas, Vasantakalpa.
RESEARCH ARTICLE Rakesh et.al / IJIPSR / 7 (7), 2019, 60-68
Department of Ayurvedic Science ISSN (online) 2347-2154
DOI: 10.21276/IJIPSR.2019.07.07.838
Available online: www.ijipsr.com July Issue 61
INTRODUCTION
Rasashatra is a branch which deals with pharmaceutics of Rasaushdhies. Pharmaceutical
technology includes various sanskara (processing) like Shodhana (purification), Jarana
(Roasting),Marana (Incineration) etc. Rasaushadhies have unique place in Ayurvedic therapeutics
because of their qualities like „Alpamatropyogitvat‟ (used in less dose), „Arucheraprasangat‟ (no
incidence of bad taste) and „Kshipramarogyadayitvat‟(quick in combating disease pathology) [1].
These Rasaushadhi has been broadly classified into Kupi Pakwa Rasayana, Pottali and Khalviya
Rasayana [2].
Khalviya Rasayana has an edge over other dosage forms in terms of its components and efficacy.
Processed metal, minerals and poisons with herbal drug not only potentiates their action but also
increases their Shelf life. It also has added benefits of palatability, metered dosage and portability.
These boons are accompanied in relatively less doses. Therefore, Kharaliya Rasayanais more
popular than any other dosage form. The important principle involved in formulating Khalviya
Rasa are Samyojanai.e. mixing of ingredients in specified manner and Bhavana. The examples of
Vasantkalpas are Suvarnamalini-vasant, Laghumalini-vasant and Madhu Malini Vasanta. Madhu
Malini Vasanta Rasa comes under Khalviya Rasayana category of Rasaushadhi. The common
ingredients of Vasantakalpa are Kharpar and Shweta Maricha but in Madhumalini Vasanta,
Hingula is a main ingredient. Preparation of compound and its efficacy has been mentioned in
several classics [3]. The main ingredients of Madhumalini Vasant are ShuddhaHingula,
Kukkutanda (Whole Egg), Shweta Marich (Piper nigram), Priyangu (Callicarpamacrophylla),
Kachora (Curcuma zedoaria) and Dadim (Punicagranatum), Nimbu (Citrus acida) used as
Bhavanadravya [4].
Properties & Therapeutic uses of Madhumalini Vasant [5]
Guna- Katuras, Ushna Virya, Madhur Vipak. It is used as Balya,Vrushya, Rasayana,
Garbhavruddhikar. It is used in chronic fever, cough, beneficial in pregnancy with debility,
aneamia, asthma, chronic respiratory problems. Dose- 1/4-1/2 gunj, (30-60mg) 2-3 times a day
with Honey. Madhumalini Vasanta is a Khalviya Rasayana. It has an edge over other dosage
forms in terms of its components and efficacy. Processed metal, minerals and poisons with herbal
drug not only potentiates their action but also increases their shelf life. It also adds benefits of
palatability, metered dosage and portability.
RESEARCH ARTICLE Rakesh et.al / IJIPSR / 7 (7), 2019, 60-68
Department of Ayurvedic Science ISSN (online) 2347-2154
DOI: 10.21276/IJIPSR.2019.07.07.838
Available online: www.ijipsr.com July Issue 62
AIM AND OBJECTIVE
1. To study Pharmaceutical & Analytical properties of Madhumalini Vasanta as per
Rasachandanshu.
2. To study the physicochemical properties of Madhumalini Vasanta.
MATERIAL AND METHODS
1. Procurement of Raw material and its authentication.
2. Collection of Shodhan Dravyas and its analysis.
3. Preparation of Madhumalinivasant.
Material
1. Hingula-cinnabar, Kukkutanda(Whole Egg), Shweta Marich (Piper nigram), Priyangu
(Callicarpamacrophylla), Kachora (Curcuma zedoaria)
2. Aardrakaswarasa-for Hingula Shodhana,
3. Dadimswarasa –for bhavana to Shuddha Hingula
4. Nimbuswarasa –for bhavana to Madhumalini vasant.
Equipments
KhalvaYantra, Gas stove, silkcloth, knife, utensils, spoon, Glass beaker, Plastic beaker.
Method
Preparation of Madhumalini Vasant included Different steps as follow [6]
1. Hingula Shodhana by giving 7 Bhavana of Aardraka Swarasa
2. Total 7 Bhavana of Dadim Swarasa to Shuddha Hingula
3. Kukkutand (White+Yellow) blended with Hingula mixture on Mandagni
4. 7 Bhavana of Nimbuswarasa to mixture.
5. Tableting of Madhumalinivasant.
Analytical Study
Organoleptic Tests, Physical test analysis, Total Ash value, Acid insoluble ash, Acid insoluble
ash, Thin Layer Chromatography, X-Ray Diffraction. Scanning Electron microscope with EDAX
was done using standard methods.
Tableting Test for MMV tablet were done as follows-
a) Average Diameter
b) Average Weight
RESEARCH ARTICLE Rakesh et.al / IJIPSR / 7 (7), 2019, 60-68
Department of Ayurvedic Science ISSN (online) 2347-2154
DOI: 10.21276/IJIPSR.2019.07.07.838
Available online: www.ijipsr.com July Issue 63
c) Weight Variation
d) Hardness
e) Disintegration time
f) Friability Test
OBSERVATION AND RESULTS:
Chromatographic Study (TLC)-Table showing the Rf values of the samples of Madhumalini
Vasanta at 254 nm, 366 nm and Iodine Chamber-
Sample A- 1stBhavana of Nimbu Swarasa to MMV
Sample B- 3rd
Bhavana of Nimbu Swarasa to MMV
Sample C- 7th
Bhavana of Nimbu Swarasa to MMV
Table 1: Showing Thin Layer Chromatography study of MMV
Sam. 254n 366nm Iodine Chamber
No.of
spots Rf Value
No.of
spots Rf Value
No.of
spots Rf Value
A 4 0.4,0.6,0.7,0.8 3 0.4,0.6,0.8 7 0.1,0.3,0.4,0.4,0.5,0.7,0.8
B 4 0.4,0.6,0.7,0.8 4 0,4.0.5,0.7,0.8 6 0.2,0.4,0.5,0.6,0.8,0.9
C 6 0.1,0.3,0.4,0.5,0.
7,0.8 5
0.3,0.4,0.4,0.5,
0.7 7 0.1,0.3,0.4,0.4,0.5,0.7,0.8
Thin Layer Chromatography (TLC) was carried out after organizing appropriate solvent system in
which maximum seven spots were distinguished and most of the RF values were identical in the
alcoholic extract. This shows the presence of certain definite constituents in Madhu Malini
Vasanta Rasa and is helpful for the easy separation of these particles.
Table 2: Showing Chemical Tests Analysis MMV Reports of MMV-
Sr.No. Test MMV Powder
1. Total Ash 5.54 %
2. Acid Ansoluble Ash 1.69 %
3. Moisture content 5.21 %
4. PH value 2.00
SEM-EDAX Analysis Report-
Table 3: showing % of different elements in Ashuddha Hingula, Shuddha Hingula and 1st
Bhavana,3rd
Bhavana and 7th
Bhavana of NimbuSwarasa to MMV as follows
Element Weight% of
AshuddhaHingula
Weight% of
ShuddhaHingula
Weight%
1stBhavana
of MMV
Weight%
3nd
Bhavana
of MMV
Weight%
7th
Bhavana
of MMV
Carbon as C 37.72 33.63% 67.08 67.34 66.76
Oxygen as
O 4.47 10.42% 29.10 28.04 28.58
Magnesium - - - 0.11 -
RESEARCH ARTICLE Rakesh et.al / IJIPSR / 7 (7), 2019, 60-68
Department of Ayurvedic Science ISSN (online) 2347-2154
DOI: 10.21276/IJIPSR.2019.07.07.838
Available online: www.ijipsr.com July Issue 64
as Mg
Phosphrous
as P 0.28 0.45% 0.13 0.13 0.16
Sulphur as
S 9.60 10.92% 0.62 0.64 0.73
Pottasium
as K - - 0.27 0.33 0.37
Calcium as
Ca - - 0.11 0.06 0.10
Copper as
Cu - - - 0.17 0.21
Zinc as Zn - - - 0.17 -
Mercurry as
Hg 47.93 44.58% 2.69 3.00
3.10
Totals 100.00 100.00 100.00 100.00 100.00
Shuddha Hingula-SEM-Images
Shuddha Hingula-EDAX-Image
Madhumalini Vasant SEM-Images Madhumalini Vasant EDAX-Images
Fig.1: SEM analysis
XRD-X-Ray diffraction
RESEARCH ARTICLE Rakesh et.al / IJIPSR / 7 (7), 2019, 60-68
Department of Ayurvedic Science ISSN (online) 2347-2154
DOI: 10.21276/IJIPSR.2019.07.07.838
Available online: www.ijipsr.com July Issue 65
The XRD test defects the physical as well as the chemical structure of the sample. The highest
peak indicates the presence of sharp crystal structure. The large peak indicates high crystallization
and large crystal size.
It is found that, the maximum intensity was at 2 Theta =26.32 .
The XRD pattern for Shuddha Hingula sample shows that there is no remarkable change
in the value of 2 Theta angle but its width increased which shows that the particle size
decreased after Shodhana.
XRD-X-Ray diffraction-Madhumalini Vasanta Powder:
During X-Ray diffraction of Madhumalini Vasanta various peaks were obtained at 2 Theta
position. The maximum intensity of peaks was found at 2 Theta =26.38 angle but there is no
remarkable change in all 3 samples of MMV i.e. 1st Bhavana,3
rdBhavana and 7
thBhavana of
Nimbu Swarasa to MMV. Peaks are so similar that they can be superimposed upon each
other.The highest peak was obtained that Hgs.
Graph showing XRD Analysis of Madhumalini Vasant
Fig. 2: XRD Analysis of Madhumalini Vasant
Table 4: Showing Organoleptic Test of MMV tablet-
Sr.No. TEST MMV mixture
1 Sparsh Khara,Ruksha
2 Rupa Reddish brown
3 Rasa Madhur,Katu,Tikta
4 Gandha Limbu Gandhi
Table 5: Showing Physical test of MMV tablet
-
RESEARCH ARTICLE Rakesh et.al / IJIPSR / 7 (7), 2019, 60-68
Department of Ayurvedic Science ISSN (online) 2347-2154
DOI: 10.21276/IJIPSR.2019.07.07.838
Available online: www.ijipsr.com July Issue 66
DISCUSSION
Madhumalini Vasanta, is mentioned in earlier text books like Rasachandanshu and later text
books like Rasa Tantra Sara and Siddha Prayog Sangraha.The ingredients of this yoga are
Hingula, Priyangu, Kachora, Shweta Maricha, Kukkutand Rasa and Dadim Swarasa. Hingula is a
combination of Parada and Gandhaka attain a good place as a medicine in Rasa Shastra.
According to Vagbhata Priyangu has the property “Bhagna Sandhanakrith and
Brunhana.”Priyangu possess both Guru and Rukshaguna.It is Tikta Kashaya and Madhura in
Rasa,byVipaka it is Katu and by virtue of its Veerya it is Sheeta. It is said to be Tridoshshamaka
especially Vatapittashamak and Vedanasthapana. Kachora is Laghu and Tikshna in guna and
UshnaVeerya. It is Tiktha and Katu in Rasa .By vipaka it is Katu and it said to be
Kaphavatashamaka [7]. Kachora is Vedana Shamaka and Shothhara and Anulomana in nature
[8].The dehusked black pepper is known as SafedMaricha is Laghu and teekshna in Guna and
Katu in Rasa and Vipaka, its Ushna in Veerya. Owing to these attribution Safed Maricha is
generally considered to be Vatakapha Shamaka [9]. Kukkutand rasa is generally Guru and
Snigdha in guna. It is Madhura in Rasa as well as in Vipaka .The Kukkutand is generally
Vatashamaka and Vrushya and is widely used in Vatavyadhi and is given in cases of Daurbalya
and Kshaya [10]. DadimSwaras though said to be a Bhavanadravya plays a major role Dadima is
Laghu and Snigha in Guru and has Madhura ,Kashaya and Amla Rasa.The ripened fruit is
Madhura in Vipaka where as the unripen fruit is Amla in Vipaka .The veerya of Dadimais
Anushna.The sweet fruit is Tridoshgnha .The fruit is said to be Balya [11].
Total time required for Hingula Shodhana was 16 hrs 40 min and for preparation of MMV tablet
15 hrs was required. Ash value of Ashuddha Hingula was 0.39%, after Bhavana of Aardraka
Swaras it was found in Shuddha Hingula 1.82% which indicates more inorganic character of
sample. The Ash Value in Shuddha Hingula increased, it may be possible due to addition of
inorganic content present in Aardraka Swarasa and evaporation of organic substances. Acid
insoluble ash value of Ashuddha Hingulawas 0.21%,after the Bhavana of Aardraka Swarasa it
was found in ShuddhaHingula0.003%.,which indicates more organic character of the sample. pH
Tablet Test Result
Average Diameter 0.6 mm
Average Weight 134.6 mg
Weight Variation (122.7mg-145.2mg)
Hardness 2 Kg/cm squ.
Disintegration Time 18 Min
Friability Test 3.40 %
RESEARCH ARTICLE Rakesh et.al / IJIPSR / 7 (7), 2019, 60-68
Department of Ayurvedic Science ISSN (online) 2347-2154
DOI: 10.21276/IJIPSR.2019.07.07.838
Available online: www.ijipsr.com July Issue 67
Value of MMV was 2.00.It may be seen due to the addition of Aardraka Swarasa having acidic in
nature.
The comparative T.L.C. pattern of the Methanol extract of the sample obtained under different
conditions viz. UV 366nm,UV 254nm and Iodine Chamber reveals that there was no difference in
the pattern of different samples of 1st Bhavana,3rd
Bhavana and 7th
Bhavana of Nimbu Swarasa to
MMV but the intensity of the spots increased with the increase of Bhavana.
This shows the presence of certain definite constituents in Madhumalini Vasanta Rasa and is
helpful for the easy separation of these particles.
In SEM analysis, the particles were viewed under successively increased various magnification
x500, x3000.The smaller particles were found adhered to large particle. The particles of
Madhumalini Vasanta are irregular shape and having size less than 1µm to 10µm.And particles of
Shuddha Hingula are irregular shape and having size less than 1µm to 12µm.
The X-Ray diffraction patterns for all the processed sample shows that there is no remarkable
change in the value of 2Theta angle. All samples show almost identical Peaks. Peaks were so
similar that they can be superimposed upon each other. The highest peak was observed that of
Mercuric Sulphide (Hgs).Hence the prepared sample resembles the characteristics of Mercuric
Supplied i.e. Hgs.
When the hardness of the tablets was calculated with Monsanto hardness tester, it was found in
three Batches average 2 kg/cm-2.The tablet disintegration time is about 18 minutes on an average.
This is quite within the disintegration time for uncoated tablets (30 min).This time needed for
disintegration has a direct impact on its quick dissolution, absorption and bioavailability. The
Average Friability of Madhumalini Vasanta was 3.40%.This indicate certain percentage to be lost
by chipping, and will not allow any broken tablets. The friability of Madhumalini Vasant was
more, it indicates that there was need to increased % of binding agent.
CONCLUSION
Rasaushadhies have unique place in Ayurvedic therapeutics, Moisture content was high in
MadhumaliniVasanta samples may be due to hygroscopic nature of the sample. Due to repeated
bhavana of Adraka swarasa and Nimu swarasa and Dalim Swarasa Intensity of the spots increased
in TLC study. the particles of MadhumaliniVasanta are irregular shape and having size less than
1µm to 10µm and Hgs as major crystalline phase in Madhumalini Vasanta tablet.
RESEARCH ARTICLE Rakesh et.al / IJIPSR / 7 (7), 2019, 60-68
Department of Ayurvedic Science ISSN (online) 2347-2154
DOI: 10.21276/IJIPSR.2019.07.07.838
Available online: www.ijipsr.com July Issue 68
REFERENCES
1. Prof. D.A. Kulkarni Rasa Vagabhatta, Rasa Ratna Samuchchya Chapter 28/68-74 Reprint
1998, Published by Meharchanda Lachhmandas-pg 248
2. Savrikar, S., and B. Ravishankar. "Introduction to „Rasashaastra‟-The Iatrochemistry of
Ayurveda." African Journal of Traditional, Complementary and Alternative Medicines 8.5S
(2011).
3. Ankita Ingole, Abhijeet Shirkande. Ellaborative Study Of Vasant Kalpa With Special
Refferences to Karmukatwa International journal of ayurvedic & herbal medicine 5(3) May-
June. 2015, p 1807-10
4. Vd Ganagadharashastri Gune, Ayurvediya Aushsadhigunadharma Shastra, Vaidyaka Granth
Bhandara, Pune, 2001
5. Prof. Savarikar S S, translator. Rasa Chandanshu, 1sted. New Delhi: Ken-driya Ayurved
Vignan Anusandhan Parishad; 2011. P 302
6. Prof. Savarikar S S, translator. Rasa Chandanshu, 1sted. New Delhi: Ken-driya Ayurved
VignanAnusandhan Parishad; 2011. P 177
7. Pandit Hari SadasivaSastri Paradakara editor, Ashtanga Hridaya with the commentaries
Sarvangasundara of Arundatta and Ayurveda Rasayana of Hemadri, Bhisagacarya;
sutrasthana, Chapter 27, Verse 48, Chaukhamba Orientalia, Varanasi, Reprint -2000, pg 370
8. Chopra RN,Nayar SL, Chopra IC. Glossary of Indian Medicinal Plants. NewDelhi:CSIR;
1986, p.130
9. Prof. K.R. Srikantha Murthy editor. 1st ed, Susruta Samhita, Sutrasthan, Chapter 46, Verse
95. Vol-II. Varanasi: Chaukhamba Orientalia, 2001;pg387
10. Rastantrasaar & Siddhaprayog Sangrah, vol 2.17th ed. Ajmer: Krishan Gopal Ayurved
Bhawan;2013. P 19
11. The Bhavprakashnighantu with elaborated Hindi commentary by Padmashri prof. K.C.
Chunekar, edited by Late Dr. G.S. Pandey: edition of 2010: Amaradiphalavarga; verse 101-
104, page no-381.
Tikle et al. European Journal of Biomedical and Pharmaceutical Sciences
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216
AN AYURVEDA REVIEW ON KHAGESHWARA RASA W.S.R. TO METHOD OF
PREPARATION
Dr. Swati Dongre1*
and Dr. Rakesh Ganvir2
1Asst. Professor, Shree Ayurved Mahavidyala, Nagpur, India.
2Asst. Professor, Shri K R Pandav Ayurved College and Hospital, Nagpur, India.
Article Received on 13/01/2020 Article Revised on 02/02/2020 Article Accepted on 23/02/2020
INTRODUCTION Khageshwara Rasa is considered as Kharaliya and
Kupipakva Rasayana mainly consisted of ingredients
such as; Parada, Gandhaka, Kasisa and Arjuntwaka as
Bhavnadravya. The Parada, Gandhakakajjali offers
Yogvahi while Kasisa imparts Ushna & Tikshna Guna
thus pacifies Bhrajaka Pitta of skin and helps in skin
problems. Jarana is major process involves in
preparation of Khageshwara Rasa, this process imparts
safety in drug safe and Khageshwara Rasa become
nontoxic to human use. The manufacturing process
enhances therapeutic properties of Khageshwara Rasa so
it can be used effectively for the management of Shwitra.
Khageshwara Rasa recommended to cures skin diseases
such as; Kushtha & Shwitra. The Kharaliya and
Kupipakvakalpana involved in preparation of
Khageshwara Rasa thus it possess several beneficial
effects of Rasaushadhis such as; palatability, potency,
safety and long shelf life.
Rasa Ratna Sammuchaya described Khageswara Rasa as
Sagandha, Saagni Antardhuma Kupipaka Rasayana
which is prepared from detoxified mercury (Shuddha
Parada), non-toxic sulfur (Shuddha Gandhaka) and pure
green vitriol (Shuddha Kasisa). These ingredients used in
equal proportions. The chief ingredients first subjected to
Bhavana of Arjuna twak kwatha than pellets preparation
from Bhavita mixture and finally subjected to Kupipaka
for 36 hours.
General considerations related to Preparation of
Khageshwara Rasa This drug is prepared from purified Parada, Gandhaka
and Kasisa, method also involves use of Bhavanadravya
Arjuntwak. Shodhana & Marana and Kupipaka etc. are
major procedures associated with the preparation of
Khageshwara Rasa. The quantity of major ingredients
mentioned in Table 1. The various techniques involved
in the preparation of Khageshwara Rasa are depicted in
Figure 1.
Table 1: Chief ingredients involved in the preparation
of Khageshwara Rasa
S. No. Ingredients Quantity
1 Parada 1 Pala
2 Gandhaka 1 Pala
3 Kasisa 1 Pala
4 Arjuna twak -
SJIF Impact Factor 6.044 Review Article
ejbps, 2020, Volume 7, Issue 3, 216-218.
European Journal of Biomedical AND Pharmaceutical sciences
http://www.ejbps.com
ISSN 2349-8870
Volume: 7
Issue: 3
216-218 Year: 2020
*Corresponding Author: Dr. Swati Dongre
Asst. Professor, Shree Ayurved Mahavidyala, Nagpur, India.
ABSTRACT
The holistic science of India Ayurveda offers several theories and principles for the maintenance of healthy
wellbeing and in this regards Ayurveda described use of many classical formulations that helps to remain healthy.
The unique, original and logical fundamentals of Ayurveda provide efficient and safer ways to remain free from
diseased condition. Rasashastra is one such modality of Ayurveda that deals with science of Rasa; mineral, metals
and herbal poisons. The formulations prepared from concepts of Rasashastra (Rasaushadhis) offers quick action,
effect in small dose, palatability and good bioavailability therefore provides several health benefits in many health
ailments. Khageshwara Rasa is one such drug that used for various purposes, considering importance of this
formulation present article reviewed some aspects of Khageshwara Rasa.
KEYWORDS: Ayurveda, Rasashastra, Rasaushadhis, Khageshwara Rasa.
Tikle et al. European Journal of Biomedical and Pharmaceutical Sciences
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217
Figure 1: Various techniques involved in the preparation of Khageshwara Rasa.
Considerations related to Parada Shodhana
Sudha, Saindhava and Rasona mainly employed for this
purpose. Sudha absorb impurities soluble in alkali and
also absorbs trace elements. During process of triturating
Lavana helps to dissociates soluble impurities Parada
due to its Kshariya property. This all facilitate absorption
of watery and oily impurities. Rasonakalka provides
Shodhana property that helps to purify Parada.
Considerations related to Gandhaka Shodhana
Godugdha and Goghruta mainly employed for this
purpose, Goghruta helps to dissolve sulphur and thereby
facilitate its detoxification. The insoluble impurities
generally filtered off while other physical impurities
trapped in cloth. The Sheeta-Virya, Snigdha-Gunas and
Madhura Vipaka of Godugdha and Goghruta helps to
pacifies intense properties of Gandhaka thus suppress
Ushna &Teekshnaguna of Gandhaka.
Considerations related to Kasisa Shodhana Bhringaraja swarasa used for Kasisa Shodhana,
Swedana principle utilizes for this purpose which helps
to dissolve Kasisa in Swarasa, impurities can be
removed after their accumulation over cotton cloth. This
procedure imparts purified dark green in crystals.
Considerations related to Kajjali preparation
Shuddha Parada and Shuddha Gandhaka used in equal
quantity for this purpose, free mercury can be identified
as presence of Chandrika in Kajjali, therefore Mardana
indicated till to become Nishchandrikaran. That after
Kasisa added in equal quantity and subjected to
Mardana till to get Shalakshna or fine particles which
can float on the water surface.
Considerations related to Khageshwara Rasa
preparation
Preparation of Musha, Mrutbhanada and
Valukayantra play important role in Purvakarma
procedure.
Bottle possessing heat sustaining capacity can be
used to prepare Musha.
Layers of cloth smeared with clay used to wrapping
purpose, this enhance stability during heating
process.
Musha used for keeping Kajjali of Parada,
Gandhaka and Kasisa.
Filling of Valukayantra can be done using sand in
Pradhana karma.
Mrutbhanada should be kept inside the
Valukayantra as part of main procedure.
Madhyamagni (200 – 4500C) need to be maintained
throughout the process.
Heating recommended for 36 hours then self cooling
of material recommended.
CONCLUSION
Rasashastra is one of the important aspects of Ayurveda
that encompasses various theories and principles related
to the therapeutic properties of mineral & metal based
formulations. These formulations termed as
Rasaushadhis which offers advantages of quick action,
low dose, palatability and potent efficacy. Khageshwara
Rasa is one such drug that comes under category of
Rasaushadhis. Khageshwara Rasa is Kharaliya and
Kupipakva Rasayana which prepared from Parada,
Gandhaka and Kasisa, Arjuntwaka also used as
Bhavnadravya. Khageshwara Rasa used for skin
problems such as; Kushtha & Shwitra. Parada
Shodhana, Gandhaka Shodhana, Kasisa Shodhana and
Kajjali preparation are major procedures involved in the
preparations of Khageshwara Rasa. Article concluded
that classical considerations related to the preparation of
Rasaushadhis and Kupipakva Rasayana is to be
considered carefully during preparation of Khageshwara
Rasa.
Tikle et al. European Journal of Biomedical and Pharmaceutical Sciences
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218
REFERENCES
1. Sharma Sadananda. Rasa Tarangini, Edited by
Kashinath Shastri. New Delhi: Motilal Banarasidas
publication; 1979. 11th edition, 201
2. Sharma Sadananda. Rasa Tarangini, Edited by
Kashinath Shastri. New Delhi: Motilal Banarasidas
publication; 1979. 11th edition, 82.
3. Acharya YT. Rasamritam, English translation by
Damodar Joshi. Varanasi: Chaukhambha Sanskrit
Bhawan, 1998; 315.
4. Vagbhata. Rasa Ratna Samucchaya, Hindi teeka by
Ambika Datta Shastri. Varanasi: Choukhambha
Sanskrit Bhavan; II edn, 19: 366.
5. Lavekar, Gandhidas. Laboratory guide for the
analysis of Ayurveda and Siddha formulations. New
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6. Ebany J. Martinez-Finley, Aschner M. Recent
advances in Mercury Research. Curr Environ Health
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Ambika Datta Shastri. Varanasi: Choukhambha
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8. Kasavajjhala, Sreedevi, Prasad. Jsr. (2014).
Purificatory Processes of Gandhaka as described in
the Medieval Indian text. International Research
Journal of Pharmacy, 5: 438-443.
AB
ST
RA
CT
The treatment of one disease is same as another or can be treated as that of or treated as like another disease is mentioned at different places in Ayurveda samhita. This inter subject similarities is important during treatment of disease. So it is relevant to review the description available in the ayurvedic text books in relation to same treatment.
ORIGINAL RESEARCH PAPER Ayurveda
CONCEPT OF SIMILAR TREATMENT IN AYURVEDA - A LITERATURE REVIEW.
KEY WORDS: Similar Treatment.
INTRODUCTION:The treatment of one disease is same as another or can be treated as that of or treated as like another disease is mentioned at different places in Ayurveda samhita. This inter subject similarities is important during treatment of disease. So it is necessary to find them and collect them at one place. So it can be easy to understand and easy to learn and can be utilized easily. The aim of Ayurveda is of two fold i.e. 1. Prevention of disease in healthy individual 2.Cure of the disease in diseased person. To fulfill the second aim different Acharayas have described different treatment & also same treatment for two disease. So it is relevant to review the description available in the ayurvedic text books in relation to same treatment. This article focusing the treatment similarities mentioned in Ayurveda.
OBJECTIVES: To understand the concept of similar treatment in Ayurveda.
METHODS: Manual searching and collection.
DISCUSSION:
In Ayurveda while treating the disease the hetu, dosha,
Dushya, Samprapti are important factor. According to Dosha
involved treatment of diseases may be similar. If two diseases
having same dosha predominance (eg. Pitta doshadhikya)
then treatment of those may be similar (As pittavata). In some
examples of same treatment the samprapti ghatak- dushya or
samprapti may be similar. This concept of similar treatment is
based on similar hetu, or same dosha predominance or same
dushya or same samprapti of two diseases. So it is very useful
when planning for treatment. If someone is not getting the
result with regular mentioned treatment then concept of
similar treatment can be used. The drugs mentioned in other
disease can be used in the underlying disease by using
concept of similar treatment.
CONCLUSION:
The similar treatment concept is useful for treating simple,
chronic or complicated disease.
www.worldwidejournals.com 1
Dr. Sarita Ghanshyam Gharde
Associate Professor, Dept Of Shalakyatantra, L.N. Ayurved College & Hospital, Bhopal (MP)
Dr Pradnya Dakhole*
Professor, Shalyatantra Shri K.R. Pandav Ayurved College & Hospital, Nagpur (Maharashtra) *Corresponding Author
Dr Trushna Tembhekar
Associate Professor, Shalyatantra Sri Sai Institute Of Ayurvedic Research & Medicine, Bhopal.
PARIPEX - INDIAN JOURNAL F RESEARCH | O March - 2020Volume-9 | Issue-3 | | PRINT ISSN No. 2250 - 1991 | DOI : 10.36106/paripex
SN Treatment of disease Treat as like/Treat same as
1 Grahani Ajirna & Atisar (A.H.)
2 Kshataj kasa Pittaj kasa
3 Vata, Kapha Galganda Granthi Visarpa
4 Raktapitta Pitta jwara/Ksahta kshin
5 Granthi (Amavashta) Shophavat
6 Pittaj Vrudhi chikitsa Pittaj Granthi sadrusha
7 Kaphaj Vrudhi chikitsa Kaphaj Granthi sadrusha
8 Sanniaptaj Updansha Drustha vrana
9 Asugdhar chikitsa Raktapitta
10 Kshinartav Nashtartav
11 Shatpoanak, Puya rakta Nadivrana vat
12 Vidradi, Indryudha, Gadharbi, Visphota, Gandhanama, Kaksha, Jalagadarbha, erivellika.
Pittaj Visarpa vat
13 Pittaj Abhishanda, Pittaj Adhimantha & Karnapak
Pittaj Visarpa vat
14 Masurika Piita kapha visarphavata
15 Sannirudha guda Nirudhha parkas vat
16 Adhijivaha Upjivhavat
17 Arjun Raktaj Abhishandya
18 Arma Shukravat
19 Dhumadarshi Raktapitta+Pittanashak+ Pittaj Visarpa vat
20 Sadhya Nayanabhighata Pittarakta Abhishyanda
21 Ananta vata Suryavarta vat
22 Rakta Gulma Pitta gulma
23 Pandu Chikitsa Shopha vat (Sushrut & Vagbhat)
24 Medoj Swarbheda Kaphaj Swarbheda
25 Raktaj krumi Kushtavat chikitsa
26 Mutraghata Ashamri
27 Umand Apasmar
28 Ati sweda Visarpa (Kashyap)
29 Vidradi Gulma
30 Asthila & Pratyasthila Gulma & Abhyantar vidradi
31 Bhayaj, Shikaj atisar Vatitisar
32 Dhwasak/ Vikshay Vataj Madatyaya
33 Napusankata Khatkshin vat
34 Angantuj shotha Visarpa vat
Similar treatment concept adding knowledge regarding treat ment of disease.
It is useful for multiple choice questions in different Ayurvedic competitive exams.
REFERENCES:1. Acharya Vidyadhar Shukla, Prof. Ravi Dutt Tripathi, “Charak Samhita”, Vaidya
Manorama Hindi Commentary, Vol I & II. Chaukahma publishing house, Varanasi.
2. Ambika Dutta Shastri, “Sushrut Samhita” Ayurved Tatva Sandipika”, Vol I & II. Chaukahma sankrit sanathan, Varanasi.
3. Kaviraj Atridev Gupta, “Astangsangraha,” Hindi Commentary”, vol.1 and 2.chaukhamba krushnadas Academy.
4. Dr. Brahmanand Tripathi, “Nirmala” Hindi Commentary, “Astanga Hrudayam,” Edition 2007, Vol I & II. Chaukhamba Sanskrit pratisthan, Delhi.
5. Dr. Brahmanand Tripathi, ‘Dipika’ Hindi Commentary, “Sharangdhar Samhita”.
2 www.worldwidejournals.com
PARIPEX - INDIAN JOURNAL F RESEARCH | O March - 2020Volume-9 | Issue-3 | | PRINT ISSN No. 2250 - 1991 | DOI : 10.36106/paripex
Dongre et al Journal of Drug Delivery & Therapeutics. 2020; 10(2):42-44
ISSN: 2250-1177 [42] CODEN (USA): JDDTAO
Available online on 15.03.2020 at http://jddtonline.info
Journal of Drug Delivery and Therapeutics Open Access to Pharmaceutical and Medical Research
© 2011-18, publisher and licensee JDDT, This is an Open Access article which permits unrestricted non-commercial use, provided the original work is properly cited
Open Access Research Article
An Ayurveda Perspective on Khageshwar Rasa W. S. R. to Rasayogsagar
Swati Dongre1, Rakesh Ganvir2
1 Asst. Professor, Shree Ayurved Mahavidyalaya, Nagpur, India
2 Asst. Professor, Shri K R Pandav Ayurved College and Hospital, Nagpur, India
ABSTRACT The stream of ayurveda science that deals with therapeutics properties of minerals, precious stones, metals and poisonous herbs is termed as Rasashastra. This branch not only related with therapeutic properties of Rasaushadhies but deals with processing of Rasa-Dravyas. The Rasa drugs help to treats many diseases and imparts rejuvenating effects. The theories and principles of Rasashastra help to convert toxic substance into non-toxic life saving medicines. The process involved in the preparation in of such drugs need to be followed carefully and must be analyzed to ensure safety of formulations. Considering this current study presented various analytical aspects related to the Khageshwara Rasa.
Keywords: Ayurveda, Rasashastra, Khageshwara Rasa, Analysis
Article Info: Received 22 Dec 2019; Review Completed 10 Feb 2020; Accepted 18 Feb 2020; Available online 15 March 2020
Cite this article as:
Dongre S, Ganvir R, An Ayurveda Perspective on Khageshwar Rasa W. S. R. to Rasayogsagar, Journal of Drug Delivery and Therapeutics. 2020; 10(2):42-44 http://dx.doi.org/10.22270/jddt.v10i2.3899
*Address for Correspondence:
Dr. Swati Dongre, Asst. Professor, Shree Ayurved Mahavidyalaya, Nagpur, India
INTRODUCTION
Rasashastra the important therapeutic modality of ayurveda which provides several theories and principles for the management of diseases using mineral and metal based formulations. Rasashastra mainly deals with preparations and uses of Bhasmas, Kharaliya, Pistis, Kupipakva Rasayanas, Parpati and Pottali etc. The preparations of such drugs needed uses of specific techniques like; Shodhana, Jarana and Marana, etc. These procedure converts non-consumable, toxic materials into safe and edible forms. The procedures adopted to prepare such drug must be followed as per guideline; moreover authenticity and safety of drugs must be checked through various analytical techniques which also confirm validity of procedures.
The optimization of preparatory stages is prerequisite to control quality of final product. Therefore in present study an attempt was made to perform analytical study of Khageshwara Rasa as per Ayurveda and modern science. Study aimed to authenticate quality and safety of raw materials and procedures involved in the preparation of Khageshwara Rasa. Study also establishes quality and standardization parameters for Khageshwara Rasa.
MATERIALS AND METHOD
Khageshwara Rasa prepared as per classical methods described in ancient texts of ayurveda and subjected to analytical studies as follows:
Analytical study
1. Physical analysis as per ayurveda
2. Kajjali Pariksha
3. Loss on drying
4. Total Ash
5. Acid insoluble Ash
6. Water soluble Ash
Experimental study
1. Physical analysis as per ayurveda
Physical analysis performed as per classical concepts of ayurveda and formulation checked for parameters such as; Shabda, Sparsha, Laghuta, Shlakshna, Rasa and Gandha, etc.
Shabda
Checked for metallic sound when crushed by teeth.
Sparsha
Formulation checked for the presence of coarse particles which can be detected by touch.
Varitaratva
Capacity of product to floats on the surface of water was investigated.
Dongre et al Journal of Drug Delivery & Therapeutics. 2020; 10(2):42-44
ISSN: 2250-1177 [43] CODEN (USA): JDDTAO
Nirdhuma
Production of smoke observed when putting over the fire.
Rekhapurnatva
Formulation was rubbed between thumb and index finger to observe properly of Rekhapurnatva.
Rasa
Formulation tested for its tasteless property.
2. Kajjali Pariksha
Rekhapurnatva
Kajjali was rubbed in between thumb and index finger to check whether it was entered the furrows of finger or not.
Varitaratva
It should possess property of Varitaratva when puffed on the surface of water.
Nishchandratva
Kajjali was rubbed on palm with a drop of water and was observed in bright sunlight for appearance of any shiny particle.
3. Loss on Drying
About 2 gm sample was dried at 1050C in a china dish, cooled in desiccator and weighed. Procedure repeated again until the constant weight and loss on drying was calculated as per standard formulae.
4. Total Ash
About 2 gm was incinerated at a temperature not exceeding 450oC, cooled and weighed. Procedure repeat till to get constant weight and total ash value was calculated.
5. Acid Insoluble Ash
Ash of sample was treated with dil. HCL and insoluble matter was collected and washed with hot water then insoluble matter was transferred to original crucible dried on hot plate and ignited to constant weight, this gives percentage of acid insoluble ash.
6. Water soluble Ash
Ash of sample was treated with 25 ml of water then insoluble matter was collected on filter paper, washed and ignited for 15 minutes. The subtracted value provides percentage of water soluble ash as per standard formula.
RESULTS AND DISCUSSION
The observations made during study were reported in Table 1.
Table 1: Analysis of Khageshwara Rasa
S. No. Parameters Observations/results
1 Shabda Absence of metal particles
2 Sparsha Smooth & Shalakshna
3 Rupa Black & Lustrous
4 Gandha Nirgandha
5 Varitartva Float on water
6 Rasa Tasteless
7 Loss on drying 1.84%w/w
8 Total Ash 24.25%w/w
9 Acid insoluble Ash 3.36%w/w
10 Water soluble Ash 2.37%w/w
Khageshwara Rasa is considered as Kupipakvarasayana prepared from Parada, Gandhaka and Kasisa along with Bhavana of Arjuntwakakwath. The findings of analytical study suggested following characteristics of Khageshwara Rasa:
Shabda
There were no free metal particles observed in Kajjali.
Sparsha
It indicates smoothness.
Varitartva
Study indicates low density of formulation so it can float on water.
Rasa
Tasteless; free from metallic taste as it should be like other metallic formulations.
Gandha
Formulation does not impart smell of sulphur or other metal means free from typical metallic characteristics.
The study on modern parameters indicates that it possess significant amount of ash since Total Ash Value was observed 24.25%w/w, the component of Acid Insoluble Ash was found to be more as compared to Water Soluble Ash. Loss on drying was found below 2 %w/w which indicates complete drying or free from moisture content which is important to restore shelf life of such formulations.
Dongre et al Journal of Drug Delivery & Therapeutics. 2020; 10(2):42-44
ISSN: 2250-1177 [44] CODEN (USA): JDDTAO
CONCLUSION
Study observed low moisture content in Khageshwara Rasa, study concluded presence of inorganic matter in formulation since ash value observed at higher side. Acid insoluble Ash was found to be 3.36%w/w, so it can be concluded that more than 90% drug may be absorbed in body for therapeutic action. The formulations possess most of the characteristics properties of herbo-metallic formulations since it was observed free from metal particles, possess smoothness, low density and tasteless. It does not impart smell of sulphur or other metal means free from typical metallic odour. Study concluded that these analytical studies can be used to authenticate quality of Khageshwara Rasa; however further standardization studies with validation parameters recommended to establish quality of Khageshwara Rasa.
REFERENCES
1. Sharma Sadananda. Rasa Tarangini, Edited by Kashinath Shastri. New Delhi: Motilal Banarasidas publication; 1979. 11th edition. Pp 201.
2. Wadekar MP, Patel RK, Preparation and characterization of a copper based Indian traditionaldrug: Tamra bhasma, Journal of Pharmaceutical and Biomedical Analysis, 39, 2005, 951–955.
3. Acharya YT. Rasamritam, English translation by Damodar Joshi. Varanasi: Chaukhambha Sanskrit Bhawan; 1998. Pp315.
4. Lavekar, Gandhidas. Laboratory guide for the analysis of Ayurveda and Siddha formulations. New Delhi: CCRAS-AYUSH, Ministry of Health and F.W., Govt. of India. 2009. pp 27.
5. Kumar CS, Moorthi C, Prabu PC, Jonson DB, Venkatnarayan R. Standardization of anti-arthritic herbo-mineral preparation. Res J Pharma, Biol and Chem Sci. 2011; 2:679.
6. Vagbhata. Rasa Ratna Samucchaya, Hindi teeka by Ambika Datta Shastri. Varanasi: Choukhambha Sanskrit Bhavan; II edn: 19. Pp 61.
7. Shyama SA, Rasayana S. Rasayana Sara. 5th ed. Varanasi: Shyama Sundar Rasayanshala Prakashan; 1997.
8. Lagad CE, Sawant RS, Yelambkar P. An approach towards standardization of Swarna Makshik Bhasma (An ayurveda preparation) Int J Res Ayu Pharm. 2011; 2:723–9.
9. Shinde, Application of Quality Control Principles to Herbal Drugs, International Journal of Phytomedicine, 1, 2009. 4-8.
10. Neeli R.E, Kamta P.N and Pradeep. Standardization strategies for herbal drugs-An Overview. Res, J. Pharm. Tech.,2008; 1(4): 311-314.
Pradnya Dakhole and Prashant Dakhole. / International Journal of Medicine and Health Profession Research. 7(1), 2020, 25-28.
Review Article ISSN: 2394 – 7403
International Journal of Medicine
and. Health Profession Research
Journal home page: www.ijmhpr.com
https://doi.org/10.36673/IJMHPR.2020.v07.i01.A07
THERAPEUTIC IMPORTANCE OF KSHARA, W.S.R. TO PANEEYA KSHARA IN ASHMARI: AN AYURVEDA REVIEW
Pradnya Dakhole*1 and Prashant Dakhole
2
1*
Shalya Tantra, Shri. K. R. Pandav Ayurveda College and Hospital, Nagpur, Maharashtra, India. 2Shalya Tantra, Mandsaur Ayurveda College, Mandsaur, Madhya Pradesh, India.
ABSTRACT Ayurveda mentioned various materials obtained from natural sources for different therapeutic purposes. Kshara Kalpana is one example of such types of materials which is extensively used in Shalya Tantra. These are alkaline preparations made from natural materials like; coral, Mulaka, Snuhi and Arka, etc. Kshara composed of ashes of herbs and mineral based products. These preparations are used for many therapeutic purposes and play vital role in para-surgical interventions. Kshara preparations are used in Mutrashmari, Arshas, Nadi Vrana and Bhagandhara, etc. Kshara Sutra is mainly employed in treatment of Bhagandar, Arsha and in various ailments where Lekhan and Ksharan are expected. Considering these entire conditions present article emphasizes therapeutic importance of Kshara, W S R, to Paneeya Kshara in Ashmari.
KEYWORDS Kshara, Paneeya Kshara, Ashmari and Kshara Sutra.
Author for Correspondence: Pradnya Dakhole,
Shalya Tantra, Shri,
K. R. Pandav Ayurveda College and Hospital,
Nagpur, Maharashtra, India.
INTRODUCTION Ashmari is a condition which involves pathological consequences of urinary stone and considered as Urolithiasis in modern medical sciences. The
condition mainly affects functioning of kidney leading to the urinary infections and disturbance in urination. Pathologically disease associated with
vitiation of Mutravah Srotas which may occur due to the faulty diet, suppressing natural urges, Madyapana, Matsya sevan, alcoholism and smoking,
etc. The symptoms of Ashmari are Mutrakriccha, Jwara, Aruchi, Vedana, Sotha and Mutravikirna. The pathogenesis starts with Apathyasevan and
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Pradnya Dakhole and Prashant Dakhole. / International Journal of Medicine and Health Profession Research. 7(1), 2020, 25-28.
accumulation of etiological factors which aggravates Doshas, these vitiated Doshas when mixes with Mutra then Vata dries up Mutra Sthansanshray resulting formation of renal stone and urinary path obstruction. There are various types of renal stones described by modern science as depicted in Figure No.1.
Ayurveda elaborated uses of Aushadha chikitsa, Shastra Chikitsa and Kshara Chikitsa, etc. for the management of Ashmari.
KSHARA IN SHALYA TANTRA Pratisaraniya Kshara Pratisaraniya Kshara mainly employed in Charmakila, Dadrumandala, Kitibha, Bhagandar, Arsha, Dushta Vrana and Vyanga. Paneeya Kshara
Paniya Kshara for Visha, Gulma, Garavisha, piles and abcess.
Acharya Susrutha specifically described uses of Paneeya Kshara for the management of such types of conditions. These therapies help to disintegrate and remove calculi. Paneeya Kshara cure symptoms such as pain and burning sensation, it also reduces chances of recurrence. Varunadi Gana Dravyas of Kshara helps in Ashmari at initial stage. The health benefits of Kshara in Ashmari as per ayurveda are as follows:
These therapies offer Chhedana and Bhedana
properties thus help to disintegrate urinary stones.
Paneeya Kshar imparts Lekhana effects thus
relieve pain. Mutrala effect helps to facilitate urination.
Tridoshghnata effect of therapy helps to
break Tridoshaj Samprapti of disease.
Ksharan properties of Kshara detoxify Mala and removes waste.
Pacify vitiated Dhatus and Doshas.
Shodhana and Ropana properties of Kshara provide symptomatic relief in urinary and ano-rectal problems.
Kshara predominantly possess corrosiveness
and Teekshna properties thus destroy and disintegrate stone.
Shlakshna Guna and quick action imparts immediate relief.
Preparation of Paneeya Kshara The main ingredients are Sesamum indicum, Achyranthus aspera, Butea frondosa, Musa sapientum and Emblica officinale. Kshara was obtained from ash of ingredients. The pH of final preparation maintained neutral or alkaline. Kshara Properties
Lavana Rasa Ruksha and Teekshna Guna Ushna Virya Katu Vipaka
Paniya Kshara removes Krimi thus provide relief in infections caused by renal stone. It relieves constipation, Agnimandya and Ajirna induced by
urinary stone. Kshara offers cleansing property thus help to remove debris, waste and stone. Kamalnal acts as an alkalizer and possess Sheetveerya
property, facilitate disintegration and removal of stones from urinary tract. The Lavana Rasa, Ruksha Guna, Ushna Virya and Katu Vipaka of Kshara provide Ashmari Chedana and Mutrakrichrahara
effects. Paniya Kshara acts on all types of renal calculi but calcium stones and uric acid stones mainly disintegrate within few days since these calculi are affected easily by alkaline materials possessing Ushna property. Alkali preparation like Kshara helps to neutralizes acidic pH thus prevents chances of stone formation.
Alkali preparation gives relief in symptoms of renal calculi. Kapha vitiation is mainly considered
responsible for the formation of Ashmari. Kshara
relieves vitiated Kapha thus prevent chances of Ashmari. Teekshna and Ushnaguna of Kshara help
to alleviate Kapha and Vata therefore reduces pathogenesis of disease. Lavana rasa and
Ushnavirya of Kshara helps to dissolve renal calculi. Sookshma and Snigdhaguna of Kshara reduce
Kathinata of Ashmari. Diuretic property of drug reduces symptoms of dysuria and suppresses
Koshtagat Vaat thus relieves abdominal pain associated with renal stone.
Available online: www.uptodateresearchpublication.com January – June 26
Pradnya Dakhole and Prashant Dakhole. / International Journal of Medicine and Health Profession Research. 7(1), 2020, 25-28.
Advantages of Kshara in Ashmari
Less chances of recurrence
Safe in terms of complications and adverse effects
Better tolerance Better palatability
Raw material easily available & easy to
prepare
Good acceptability from patient and physician point of view.
Pathya Liquid diets and intake of water Mudga, Yava and Jeerna Shali Vamana and Virechana Langhana Apathya Oily, spicy, sour and acidic diet Kharjur, Jambu and Shushkann, etc. Vegaudeerana Krodha and Ativyayam, etc.
Figure No.1: Various types of renal stone as per modern science
CONCLUSION
Paneeya Kshara can be used in Ashmari since it offers Ashmarigna action. Chedhana, Bhedana and
Mutrala effects of Kshara help in the management
of Ashmari. The uses and preparation of Paneeya
Kshara is simple as compared to other therapy. It is
considered as safe and effective therapy with good acceptance. Paniya Kshara eliminates Krimi hence
relief infections of urinary tract. It relief
Agnimandya, Ajirna and constipation induced by
urinary stone. Kshara cleanse renal stone due to its alkalizer and Sheetveerya property. It facilitates
disintegration followed by removal of renal stones
from urinary tract. Kshara pacifies vitiated Kapha
thus prevent chances of Ashmari. Kshara alleviates
Vata therefore reduces abdominal pain, Lavana rasa of Kshara dissolves renal calculi, Snigdhaguna of
Kshara reduce Katinatha of Ashmari and diuretic
property reduces dysuria thus provide overall relief
in renal stone.
ACKNOWLEDGEMENT The authors wish to express their sincere gratitude to Shalya Tantra, Shri. K. R. Pandav Ayurveda College and Hospital, Nagpur, Maharashtra, India for providing necessary facilities to carry out this research work.
CONFLICT OF INTEREST
We declare that we have no conflict of interest.
BIBLIOGRAPHY
1. Sharma S. Rasa Tarangini, Hindi commentary by Shastri Kashinatha, Motilal Banarasidas, Delhi,
11/34, 11th
Edition, 1989, 583. 2. Sharma P V. Sushruta, Sushruta Samhita,
English commentary by Chaukhamba Bharati Academy, Sutra Sthana Varanasi, 11/1, Reprint Edition, 2010, 113.
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3. Sharma H S. Nagarjuna, Rasendramangala, Chaukhambha Orientalia, Varanasi, 2/20-22, Reprint Edition, 2008, 34-35.
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7. Yadavji Trikamji Acharya and Naarayana Ram Acharya. Acharya Sushruta, Sushruta, Samhita, Dalhana. Nibandhasangraha commentary, Chaukhambha Sanskrit Sansthan, Sutrasthana Varanasi, Reprint, 11(10), 2013, 46.
8. Sridevi V, Rajya Lakshmi I, Sanjeeva Rao I. Urolithiasis Mutrashmari, In Lakshmi Chandra Mishra editor, scientific basis for Ayurvedic Therapies, Boca Raton, CRC Press LLC, 2004, 511-535.
9. TripathiHariprasadPt,HaritaSamhita, Published by Chaukhamba Krusnadas Academy,
Varanasi-221001 (India), 1st
Edition, 2005, 396-397.
Please cite this article in press as: Pradnya Dakhole and Prashant Dakhole. Therapeutic importance of Kshara, W.S.R. to Paneeya Kshara in Ashmari: An ayurveda review International Journal of Medicine and Health Profession Research, 7(1), 2020, 25-28.
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Academic (Allied-UG &PG)
(0253) 2539198/6659198
MUHS InternationalEducation HUB
Shri. Sandeep A. RathodCo-ordinator [email protected] (0253) 2539156 /
6659197University Department Cell Shri. Pravin Ghatekar [email protected] (0253) 2539206 /
10/8/2020 Welcome to MUHS
https://www.muhs.ac.in/contact_us.aspx 2/2
(Ph.D) Statistical Officer 6659206University Department Cell(Fellowship)
Shri. Sandeep A. RathodSection Officer [email protected] (0253) 2539156 /
6659197
Planning Board Dr. Rajeev T. AherAsst. Registrar [email protected] (0253) 2539244/
6659244(0253) 2539242 /6659242
Special Cell Shri. Sanjay R. NerkarAsst. Registrar [email protected]
(0253)2539211/6659211(0253)2539157 /6659157
CET/Eligibility Shri. Sanjay R. NerkarAsst. Registrar [email protected] (0253) 2539232 /
6659232(0253) 2539231 /6659231
Student Welfare Dr. Sandeep GundreDirector (Student Welfare) [email protected]
(0253) 2539170 /6659170 (0253) 2539171 /6659171
Computer (Software) Shri. Madhukar BhiseComputer Programmer [email protected] (0253) 2539180/
6659180Computer (Hardware &Networking)
Shri. Madhukar BhiseComputer Programmer [email protected] (0253) 2539180/
6659180
Electrical EngineeringShri. Sanjay MaratheUniversity Engineer(Electrical)
[email protected] (0253) 2539185/6659185
Civil EngineeringShri. Sanjay MaratheUniversity Engineer(Electrical)
(0253) 2539236/6659236(0253) 2539162 /6659162
Public Relation Dr. Swapnil TornePublic Relation Officer [email protected] (0253) 2539175/
6659175(0253) 2539176/6659176
Establishment Vd. Udaysinh RaoraneDy. Registrar [email protected] (0253) 2539161/
6659161(0253) 2539163/6659163
URD Dr. Dipanjali LomateAsso. Professor [email protected] (0253) 2539302 /
6659302(0253) 2539298/6659298
IMETTI Dr. Payal BansalProfessor [email protected] (0253) 2539306 /
6659306(0253) 2539195/6659195
Legal and Grievances Shri. S. S. KulkarniLaw Officer [email protected] (0253) 2539237/
6659237(0253) 2539240 /6659240
Library Shri. Prashant ShindeLibrarian [email protected] (0253) 2539108 /
6659108(0253) 2539298/6659298
Public Information Cell (RTI) Dr. R.T. AherAsst. Registrar [email protected] (0253)2539231 /
6659232(0253)2539232 /6659232
Examination (RTI) [email protected] (0253)2539226 /6659226
(0253)2539223 /6659223
AYUSH Vd. Pradeep AwaleAssistant Professor [email protected] (0253)2539121 /
6659121(0253)2539121 /6659121
Health Centre Dr. Sachin GaikwadMedical Officer [email protected] (0253)2539126 /
6659126(0253)2539125 /6659125
Purchase Shri. Prakash PatilAsst. Registrar [email protected] (0253)2539149 /
6659149(0253)2539146 /6659146
Administration Shri. Rajendra B. NakaveAsst. Registrar [email protected] (0253) 2539151/
6659151(0253) 2539150/6659150
Reception Smt. Anita MohiteTel. Operator
(0253) 2539100 /6659100(0253) 2539300 /6659300
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