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    ORTHOPEDICS | ORTHOSuperSite.com

    Feature Article

    abstract

    Full article available online at OrthoSuperSite.com/view.aspx?rID=67563

    Effect of Preoperative Exercise onPostoperative Mobility in Obese Total JointReplacement PatientsCLAIRE E. ROBBINS, PT, DPT, MS; JAMES V. BONO, MD; DANIEL M. WARD, MD; MARILYN T. BARRY, PT;

    JANICE DOREN, PT; AMANDA MCNINCH, PT, MS

    Drs Robbins, Bono, and Ward are from the Department of Orthopedic Surgery, New England Baptist

    Hospital, Tufts University School of Medicine, and Dr Robbins and Mss Barry, Doren, and McNinch are

    from the Department of Rehabilitation Services, New England Baptist Hospital, Boston, Massachusetts.

    Drs Robbins, Bono, and Ward and Mss Barry, Doren, and McNinch have no relevant financial rela-

    tionships to disclose.

    Correspondence should be addressed to: Claire E. Robbins, PT, DPT, MS, Department of Ortho-

    pedic Surgery, New England Baptist Hospital, 125 Parker Hill Ave, Boston, MA 02120 (crobbins@

    caregroup.harvard.edu).

    doi: 10.3928/01477447-20100722-09

    There has been a significant increase in obesity in the United States over the past 20

    years. Reports in the literature identify the association of obesity-related osteoarthritis

    and the likelihood of future total hip arthroplasty (THA) and total knee arthroplasty

    (TKA) in this patient population. However, little is known about the effect of preopera-

    tive exercise on immediate postoperative mobility and discharge disposition in obese

    total joint replacement patients. The purpose of this study was to examine the effect of

    preoperative exercise in the obese total joint replacement patient on early postopera-

    tive mobility and discharge disposition.

    We retrospectively reviewed a consecutive series of patients with a body mass index

    (BMI) 30 kg/m2 who underwent primary total joint replacement surgery from June

    2005 through October 2005 at 1 institution. Two hundred seven patients met the in-

    clusion criteria. Sixty-five patients performed self-reported preoperative exercise, de-

    fined as physical activity deemed above and beyond that of activities of daily living.Fewer exercise patients, 6.8%, required the assistance of2 caregivers for mobility on

    postoperative day 1 vs 17.4% for nonexercisers. Fifty-four percent of patients partici-

    pating in preoperative exercise were discharged home vs 46% who did not participate

    in exercise. A preoperative exercise program can improve postoperative functional

    mobility and increase the likelihood of discharge home in total joint replacement pa-

    tients with a BMI of30 kg/m2.

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    SEPTEMBER 2010| Volume 33 Number 9

    POSTOPERATIVE MOBILITYIN OBESE TOTAL JOINT REPLACEMENT PATIENTS | ROBBINSETAL

    There has been a significant in-

    crease in obesity in the United

    States over the past 20 years. In

    2008, only 1 state, Colorado, had an obe-

    sity rate 20%.1 The National Institutes

    of Health (NIH) guidelines define obesity

    as a body mass index (BMI) of30 kg/

    m2 and morbid obesity as a BMI of40

    kg/m2.2 Body mass index is calculated by

    dividing the patients weight in kilograms

    by the square of the patients height in

    meters. Obesity is a health condition as-

    sociated with an increased incidence of

    multiple medical comorbidities, includ-

    ing osteoarthritis. Reports in the literature

    identify the association of obesity-related

    osteoarthritis and the likelihood of future

    total hip arthroplasty (THA) and total

    knee arthroplasty (TKA) in this patient

    population.3-9

    The anticipated benefits of reducing

    pain and improving function following

    joint replacement surgery should not over-

    shadow discussion of potential periopera-

    tive and postoperative risks. Obese and

    morbidly obese patients pose challenges

    not only for the surgical team, but for the

    postoperative medical, nursing, and reha-

    bilitation staff.10,11 Preoperative knowl-

    edge of the risks and benefits may prove

    invaluable to both surgeon and patient.

    In 2006, Rooks et al12 reported on the

    effect of preoperative exercise on function-al measures in men and women undergo-

    ing THA and TKA. Several authors report

    on hospital length of stay and discharge

    disposition in the obese patient popula-

    tion.5,7,10,13,14 However, less is known about

    the effect of preoperative exercise on imme-

    diate postoperative mobility and discharge

    disposition in obese total joint replacement

    patients. We hypothesize a decrease in as-

    sistance with postoperative mobility and an

    increase in patients discharged home with

    obese THA and TKA patients participating

    in a preoperative exercise program.

    MATERIALSANDMETHODSAfter institutional review board ap-

    proval, we retrospectively reviewed a con-

    secutive series of patients with a BMI of

    30 kg/m2 who underwent primary THA

    or TKA between June 2005 and October

    2005. These patients were selected from

    the hospital database. During this period,

    several orthopedic surgeons performed

    300 THAs and TKAs on this patient co-

    hort. Two hundred seven patients met the

    inclusion and exclusion criteria. Seventy-

    six patients received primary THAs and

    131 patients received primary TKAs using

    a traditional, noncomputer-assisted surgi-

    cal approach. All surgeries were elective

    procedures.

    Fifty-eight percent of the patients

    (120) were women and 42% (87) were

    men. Mean patient age at the time of sur-

    gery was 63.1 years (range, 31-87 years).

    The principal diagnosis was osteoarthritis.

    One hundred patients had a BMI of30

    kg/m2 and 107 patients had a BMI of40

    kg/m2.

    The inclusion criteria for patients

    participating in a preoperative exercise

    program included adult men and women

    between the ages of 30 and 90 years and

    an underlying diagnosis of osteoarthritis,

    rheumatoid arthritis, or traumatic arthritis

    that required a primary THA or TKA. The

    patients had a documented BMI of30

    kg/m2 during the preoperative screening

    process.

    The inclusion criteria for the compari-son group (patients who did not partici-

    pate in a preoperative exercise program)

    were the same. Exclusion criteria includ-

    ed use of the minimally invasive capsular

    preserving surgical approach with THA, a

    computer-assisted procedure, and having

    bilateral joint replacement surgeries per-

    formed on the same day.

    Patients deemed eligible following

    retrospective review of the medical re-

    cords were consecutively assigned to

    either the preoperative exercise group or

    the group that did not partake in a pre-

    operative exercise program. For purposes

    of this study, preoperative exercise was

    defined during the preoperative screen-

    ing process as participation in physical

    activity deemed above and beyond that of

    the activities of daily living. There were

    no eligibility guidelines with respect to

    type of activity or intensity. Therefore,

    self-reported, preoperative exercise or

    activity programs varied in both type

    and level of participation. Preoperative,

    self-reported physical activities included,

    but were not limited to, biking, stretch-

    ing, walking, swimming, water aerobics,

    low-impact aerobics, going to a health

    club, and participating in formalized out-

    patient physical therapy.

    Postoperative surgical and rehabili-

    tation protocols for primary THA and

    TKA were similar among the arthroplasty

    surgeons. Patients were allowed to bear

    weight as tolerated with an assistive de-

    vice. Two surgeons allowed only partial

    weight bearing during the immediate

    postoperative period. The majority of

    THA patients observed posterior THA

    precautions, and active-assisted thera-

    peutic exercises were initiated on the first

    postoperative day. At the time, there were

    slight differences with perioperative pain

    regimes among the surgeons, and 1 sur-

    geon deferred continuous passive motion

    machine application until the first postop-

    erative day with TKA patients.

    Functional mobility is defined to in-

    clude bed mobility, supine-to-sit transfers,

    and sit-to-stand transfers. A data collec-tion sheet developed by the authors was

    used to extract information from the medi-

    cal record during the retrospective review.

    The data collection sheet contained fields

    for demographic information, BMI, date

    of surgery, type of surgery/surgeon, dis-

    charge disposition, and amount of assist

    for functional mobility. The amount of as-

    sist for functional mobility was recorded

    on the first postoperative day in which

    the patient was mobilized with physical

    therapy.

    The McNemar test, typically used to

    test 2 study proportions obtained from the

    same group of respondents, was used to

    evaluate postoperative functional mobil-

    ity between the exercise and nonexercise

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    ORTHOPEDICS | ORTHOSuperSite.com

    Feature Article

    group.15 The z-test for 2 proportions was

    used to compare discharge disposition.16

    RESULTSObese and morbidly obese patients of-

    ten require more staff assistance with post-

    operative mobility after joint replacement

    surgery.5,10 Fewer preoperative exercise pa-

    tients, 6.8%, required the assistance of2

    caregivers for functional mobility on post-

    operative day 1 vs 17.4% for nonexercis-

    ers. This result was statistically significant

    (P.0261) with a 2-tailed confidence level

    of 99.8%. Tables 1 and 2 show the progres-

    sion of patients through postoperative day

    4 who required the assistance of2 care-

    givers. The postoperative protocol variance

    among surgeons did not affect the level of

    functional mobility between the 2 groups.

    Discharge disposition, home vs re-

    habilitation facility, was assessed. Fifty-

    four percent of patients participating in

    preoperative exercise were discharged

    home vs 46% who did not participate in

    exercise. Z-test calculations showed the

    difference was not statistically significant

    (P.3524).

    Of patients requiring the assistance of

    1 person for postoperative functional

    mobility, only 3 were discharged home.

    Home discharge in this cohort included

    2 exercise patients receiving THAs and

    1 nonexercise patient receiving a THA.No patients requiring increased assistance

    with mobility who underwent TKA sur-

    gery were discharged to home. No patients

    with a BMI 40 kg/m2 who required the

    assistance of2 caregivers for functional

    mobility were discharged home.

    DISCUSSIONIn November 2007, the American Med-

    ical Association, in collaboration with the

    American College of Sports Medicine,

    introduced the Exercise Is Medicine ini-

    tiative.17 Together, the 2 groups called on

    all physicians, regardless of specialty, to

    educate their patients on the importance

    of incorporating physical activity into

    their daily routines. The American Acad-

    emy of Orthopaedic Surgeons shares in

    this initiative and posts a position state-

    ment on their website, The Need for Daily

    Physical Activity, which may be used by

    both patients and health care providers as

    an educational tool when considering an

    exercise program.18 We consider the Ex-

    ercise Is Medicine initiative as a valuable

    preoperative component for all patients

    considering joint replacement surgery.

    We conducted a retrospective study to

    examine the effect of self-reported pre-

    operative exercise in the obese total joint

    replacement patient. We looked at the im-

    pact of preoperative exercise interventionon early postoperative functional mobility

    and discharge disposition. To our knowl-

    edge, this is one of the few studies to ex-

    amine the potential benefits of preopera-

    tive exercise on obese and morbidly obese

    patients undergoing primary total joint

    replacement surgery.3,12

    It was found that fewer patients who

    performed a self-reported exercise routine

    prior to joint replacement surgery required

    the assistance of2 caregivers for imme-

    diate postoperative functional mobility. A

    caveat to consider when interpreting this

    finding is that self-reported, preoperative

    exercise programs varied in both type

    and level of participation amongst obese

    total joint replacement patients. All pa-

    tients were provided the opportunity to

    report participation in preoperative exer-

    cise to a health care provider during the

    preadmission screening process, and the

    self-reported information was recorded as

    part of the medical record. However, some

    patients may have failed to consider their

    daily walk or stretching as exercise and

    therefore did not report it. A retrospective

    review of the medical record would then

    indicate the patient was a nonexerciser.

    No patients in the nonexercise group were

    contacted for clarification of preoperative

    exercise participation.

    Although more patients in the exercisegroup were discharged home compared

    to the nonexercise group, we cannot at-

    tribute this purely to preoperative exercise

    intervention.19-21 The nonrandomized, ret-

    rospective design did not control for age,

    comorbidities, socioeconomic status, pre-

    operative education, or patient expecta-

    tions and motivation.

    We recognize the limitation of a retro-

    spective study design. However, we be-

    lieve the study provides valuable insight

    into the positive postoperative effects of

    preoperative exercise in a select group of

    obese total joint replacement patients. A

    prospective, randomized controlled de-

    sign may have improved the clinical sig-

    nificance of our findings.

    Table 1

    TKA Patients Requiring the

    Assistance of

    1 CaregiverWith Postoperative

    Functional Mobility

    BMI 30 kg/m2

    WithExercise

    WithoutExercise

    Day 1 8 22

    Day 2 5 18

    Day 3 4 10

    Day 4 2 6

    Abbreviations: BMI, body mass index;TKA, total knee arthroplasty.

    Table 2

    THA Patients Requiring the

    Assistance of

    1 CaregiverWith Postoperative

    Functional Mobility

    BMI 30 kg/m2

    WithExercise

    WithoutExercise

    Day 1 6 14

    Day 2 6 9

    Day 3 2 7

    Day 4 2 3

    Abbreviations: BMI, body mass index;THA, total hip arthroplasty.

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    SEPTEMBER 2010| Volume 33 Number 9

    POSTOPERATIVE MOBILITYIN OBESE TOTAL JOINT REPLACEMENT PATIENTS | ROBBINSETAL

    CONCLUSIONA self-reported preoperative exercise

    program can improve postoperative func-

    tional mobility and increase the likelihood

    of discharge to home in total joint replace-

    ment patients with a BMI30 kg/m2. Our

    results support the feasibility of a larger,

    prospective study to examine the effect of

    formalized preoperative exercise on pa-

    tients with a BMI 30 kg/m2 vs patients

    with a BMI 30 kg/m2 anticipating total

    joint replacement surgery.

    REFERENCES1. Obesity and Overweight for Professionals:

    Data and Statistics: US Obesity Trends. Cen-ters for Disease Control and Prevention Website. http://www.cdc.gov/obesity/data/trends.html. Accessed November 12, 2009.

    2. Clinical Guidelines on the Identification,Evaluation, and Treatment of Over-Weightand Obesity in Adults: The Evidence Report,1998. National Institutes of Health Web site.http://nhlbi.nih.gov/guidelines/obesity/ob_gdlns.pdf. Accessed November 12, 2009.

    3. Busato A, Rder C, Herren S, Eggli S. In-fluence of high BMI on functional outcomeafter total hip arthroplasty. Obes Surg. 2008;18(5):595-600.

    4. Karlson EW, Mandl LA, Aweh GN, SanghaO, Liang MH, Grodstein F. Total hip replace-ment due to osteoarthritis: the importance ofage, obesity, and other modifiable risk fac-tors.Am J Med. 2003; 114(2):93-98.

    5. Vincent HK, Weng JP, Vincent KR. Effect ofobesity on inpatient rehabilitation outcomesafter total hip arthroplasty. Obesity (SilverSpring). 2007; 15(2):522-530.

    6. Gillespie GN, Porteous AJ. Obesity and kneearthroplasty. Knee. 2007; 14(2):81-86.

    7. Fehring TK, Odum SM, Griffin WL, MasonJB, McCoy TH. The obesity epidemic: its ef-fect on total joint arthroplasty.J Arthroplasty.2007; 22(6 suppl 2):71-76.

    8. Crowninshield RD, Rosenberg AG, SporerSM. Changing demographics of patients withtotal joint replacement. Clin Orthop Relat

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    10. McDonald JE, Huo MH. Total hip replace-ment: unique challenges in the obese and ge-riatric populations. Curr Opin Orthop. 2008;19(2):33-36.

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    12. Rooks DS, Huang J, Bierbaum BE, et al. Ef-fect of preoperative exercise on measures offunctional status in men and women under-going total hip and knee arthroplasty.Arthri-tis Rheum. 2006; 55(5):700-708.

    13. Barsoum WK, Murray TG, Klika AK, et al.Predicting patient discharge disposition aftertotal joint arthroplasty in the United States.J

    Arthroplasty. In press.

    14. Munin MC, Rudy TE, Glynn NW, CrossettLS, Rubash HE. Early inpatient rehabilita-tion after elective hip and knee arthroplasty.

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    15. McNemar test calculator. Dimension Re-search, Inc, Web site. http://www.dimension-research.com/resources/calculators/mcne-mar.html. Accessed November 25, 2009.

    16. Z-test for two proportions calculator. Dimen-sion Research, Inc, Web site. http://www.di-mensionresearch.com/resources/calculators/ztest.html. Accessed November 25, 2009.

    17. Davis RM. Exercise: a dose of medicine wecan all use. American Medical AssociationWeb site. http://www.ama-assn.org/ama/no-index/news/18118.shtml. Published Novem-ber 8, 2007. Accessed November 25, 2009.

    18. Position statement: the need for daily physi-cal activity. American Academy of Orthopae-dic Surgeons Web site. http://www.aaos.org/about/papers/position/1138.asp. PublishedFebruary 1997. Updated December 2008.Accessed November 25, 2009.

    19. Oldmeadow LB, McBurney H, RobertsonVJ, Kimmel L, Elliott B. Targeted postopera-tive care improves discharge outcome afterhip or knee arthroplasty.Arch Phys Med Re-habil. 2004; 85(9):1424-1427.

    20. de Pablo P, Losina E, Phillips CB, et al. De-terminants of discharge destination follow-ing elective total hip replacement. Arthritis

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    21. Bozic KJ, Wagie A, Naessens JM, Berry DJ,Rubash HE. Predictors of discharge to an in-patient extended care facility after total hip orknee arthroplasty.J Arthroplasty. 2006, 21(6Suppl 2):151-156.

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