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John Kasckow, M.D., Ph.D. Page 1 CURRICULUM VITAE University of Pittsburgh School of Medicine JOHN KASCKOW, M.D., Ph.D. Home Address: 1703 Bear Run Drive, Pittsburgh, PA 15237 (513) 652-5264 Business Address: VAPHS, University Dr, Behavioral Health Pittsburgh, PA 15240 Business phone: (412) 360-6344 cell: (513) 652-5264 Business fax: (412) 954-4305 Birthdate: 2/17/58 Birthplace: Baltimore, MD USA Citizen Email: [email protected] Education and Training Undergraduate 1976-1980 University of Rochester, Rochester, NY BS Neuroscience Graduate 1980-1987 University of Rochester, Rochester, NY MD, PhD Neuroscience Advisor Robert Herndon, MD Postgraduate 1987-90 Duke University Psychiatry (R1-3) Director: Allan Maltbie, MD 1990-91 UCLA Psychiatry (R4) Director: Joel Yaeger, MD 1991-93 Salk Institute Molecular Endocrinology Fellowship Advisor: Wylie Vale, PhD 1987 Doctor of Medicine, University of Rochester, Rochester, New York 1985 Doctor of Philosophy in Neuroscience, Center for Brain Research

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Page 1: John Kasckow, M.D., Ph.D. Page 1John Kasckow, M.D., Ph.D. Page 3 11/2006-2/2008 VA Pittsburgh Health Care Center Behavioral Health

John Kasckow, M.D., Ph.D. Page 1

CURRICULUM VITAE

University of Pittsburgh School of Medicine

JOHN KASCKOW, M.D., Ph.D. Home Address: 1703 Bear Run Drive, Pittsburgh, PA 15237 (513) 652-5264

Business Address: VAPHS, University Dr, Behavioral Health Pittsburgh, PA 15240

Business phone: (412) 360-6344 cell: (513) 652-5264 Business fax: (412) 954-4305

Birthdate: 2/17/58 Birthplace: Baltimore, MD

USA Citizen

Email: [email protected]

Education and Training

Undergraduate

1976-1980 University of Rochester, Rochester, NY BS Neuroscience

Graduate

1980-1987 University of Rochester, Rochester, NY MD, PhD Neuroscience

Advisor Robert Herndon, MD

Postgraduate

1987-90 Duke University Psychiatry (R1-3) Director: Allan Maltbie, MD 1990-91 UCLA Psychiatry (R4) Director: Joel Yaeger, MD

1991-93 Salk Institute Molecular Endocrinology Fellowship

Advisor: Wylie Vale, PhD

1987 Doctor of Medicine, University of Rochester, Rochester, New York

1985 Doctor of Philosophy in Neuroscience, Center for Brain Research

Page 2: John Kasckow, M.D., Ph.D. Page 1John Kasckow, M.D., Ph.D. Page 3 11/2006-2/2008 VA Pittsburgh Health Care Center Behavioral Health

7/1993-6/1995 Department of Psychiatry and Behavioral Sciences Emory University Medical Center

Assistant Professor

Director, Florida Hall Clozapine Clinic, Grady Hospital Atlanta, GA

1/1995-6/1995 Atlanta VAMC Psychiatry Service Atlanta, GA

Co-director, Geropsychiatry Clinics Director, Basic Research

7/1995-8/00 University of Cincinnati Department of Psychiatry

Director, Geropsychiatry Subdivision Director, Geropsychiatry Training Assistant Professor

9/2000-8/03 University of Cincinnati Department of Psychiatry

Director, Geropsychiatry Subdivision Director, Geropsychiatry Training Associate Professor

10/2003-11/06 University of Cincinnati Department of Psychiatry

Director, Geropsychiatry Subdivision Director, Geropsychiatry Training Professor

7/1995-11/2006 Geriatric Psychiatry Cincinnati VA Medical Center

Director, Geropsychiatry

John Kasckow, M.D., Ph.D. Page 2

University of Rochester, Rochester, New York Dissertation entitled: "Mechanism of Phospholipase A2-Induced Conduction Block in Bullfrog Sciatic Nerve"

PREVIOUS POSITION(S)

Page 3: John Kasckow, M.D., Ph.D. Page 1John Kasckow, M.D., Ph.D. Page 3 11/2006-2/2008 VA Pittsburgh Health Care Center Behavioral Health

John Kasckow, M.D., Ph.D. Page 3

11/2006-2/2008 VA Pittsburgh Health Care Center Behavioral Health

Staff Psychiatrist Core Faculty Member Mental Illness Research, Education and Clinical Center

VA Liaison, WPIC Geropsychiatry Training Program

Department of Psychiatry University of Pittsburgh Pittsburgh, PA

Visiting Professor

Faculty Member, UPMC Advanced Center for Interventions and Services Research in Late Life Mood Disorders

2/2008-present VA Pittsburgh Health Care Center Behavioral Health,

Staff Psychiatrist Core Faculty Member, Mental Illness Research, Education and Clinical Center VA Liaison, WPIC Geropsychiatry Training Program

Department of Psychiatry University of Pittsburgh Pittsburgh, PA

Professor

Faculty Member, UPMC Advanced Center for Interventions and Services Research in Late Life Mood Disorders

Since 7/2011 Faculty Member, UPMC Advanced Center for Prevention Research in Late Life Mood Disorders

Page 4: John Kasckow, M.D., Ph.D. Page 1John Kasckow, M.D., Ph.D. Page 3 11/2006-2/2008 VA Pittsburgh Health Care Center Behavioral Health

John Kasckow, M.D., Ph.D. Page 4

Since 4/2010 VA Pittsburgh Health Care Center Director of VA Services, University of Pittsburgh Geropsychiatry Training Program

Since 4/2011 Core Faculty Member Center for Health Equity Research and Promotion

Non- Academic

8/1991-6/1993 Athena Counseling Center/Inland Empire Mental Health Moreno Valley and Riverside, CA

Psychiatrist

2-6/1993 San Bernardino Mental Health San Bernardino, CA

Psychiatrist

5/2005-5/2012 Mercy Hospital Cincinnati, OH

Psychiatrist

6/2012-present UPMC Northwest UPMC McKeesport

Psychiatrist

Certifying Boards

National Board of Medical Examiner #313023, 1988 ABPN - General Psychiatry #037282, 1993 ABPN - Geriatric Psychiatry, #1440, 1995, recertified 2006

Medical Licensure (active)

Ohio 35-06-8449-K, since 1995 Kentucky 39491, since 2005 Pennsylvania 430066, since 2006

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John Kasckow, M.D., Ph.D. Page 5

MEMBERSHIP IN PROFESSIONAL SOCIETIES:

American Psychiatric Association American Association of Geriatric Psychiatry Society for Neuroscience American Society for Biological Psychiatry International College of Geriatric Psychoneuropharmacology

AWARDS AND HONORS:

VACO, Office of Mental Health Operations, Inclusion into the OMHO Strong Practices SharePoint site for the project: “Using Telehealth to Monitor Suicide Risk”, 2013. Who’s Who in Medicine Higher Education, 2008 University of Rochester- NIMH Summer Research Fellow in Suicide Prevention, 2007 and 2008 AAGP-NIMH Summer Research Fellow in Geriatric Psychiatry, 1996 Society of Biological Psychiatry Dista Fellowship Award, 1994 American Society for Neurochemistry Travel Award, 1992 American Psychiatric Association/Dista Products Resident Research Award, 1990 Highest Distinction with Honors in Neuroscience University of Rochester, 1980 Summa Cum Laude, University of Rochester, 1980 Phi Beta Kappa, University of Rochester, 1979 Rochester Plan Early Selection Program University of Rochester Medical Center, 1978 Rigby Wile Prize in Biology, University of Rochester, 1977

PEER REVIEWED PUBLICATIONS

1. Herndon RM, Kasckow JW. Electron Microscopic Studies of Cerebrospinal Fluid Sediment in Demyelinating Disease. Annals of Neurology 1978; 4:515-523.

2. Kasckow JW, Tabira T, Itoyma Y, Kuroiwa Y, Nagai Y. Experimental Allergic Encephalomyelitis: Suppression with SD-170, a New Synthetic Drug. Japanese Journal of Experimental Medicine 1981; 51:293-298.

3. Kasckow JW, Thomas GJ, Herndon RM. Performance Factors in Regard to Impaired Memory and Tolerance Induced by Atropine Sulfate. Physiological Psychology 1984; 12:111-115.

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4. Tipperman R, Kasckow JW, Herndon RM. The Fine Structure of Macrophages in Lysolecithin-Induced Demyelination: A Freeze-Fracture Study. Journal of Neuropathology and Experimental Neurology 1984; 43:522-530.

5. Kasckow JW, Abood LG, Hoss W, Herndon RM. Mechanism of Phospholipase A2-Induced Conduction Block in Bullfrog Sciatic Nerve. II. Biochemistry Brain Research 1986; 373:329-388.

6. Kasckow JW, Abood LG, Hoss W, Herndon RM. Mechanism of Action of Phospholipase A -Induced Conduction Block in Bullfrog Sciatic Nerve. I. 2

Electrophysiology and Morphology. Brain Research 1986; 373:384-391.

7. Kasckow JW, Cain ST, Nemeroff CB. Neurotensin Effects on Calcium/Calmodulin-Dependent Protein Phosphorylation in Rat Neostriatal Slices. Brain Research 1991; 545:343-346.

8. Kasckow JW, Tillakaratne NJK, Kim H, Strecker GJ, Tobin AJ and Olsen RW. Expression of GABA Receptor Polypeptides in Rat Clonal Cell Lines. Brain Research 1992; 581:143-147.

9. Parkes D, Kasckow JW, Vale, WW. Carbon Monoxide Modulates Secretion of Corticotropin-Releasing Factor (CRF) from Rat Hypothalamic Cell Cultures. Brain Research 1994; 646:315-318.

10. Kasckow JW, Owens M, Stipedic M, Han J, Nemeroff CB. The BE (2)-C Neuroblastoma Cell Secretes Corticotropin-Releasing Factor and Is Responsive to Forskolin. Life Sciences 1994; 54:1825-1829.

11. Kasckow JW, Parkes D, Owens M, Stipedic M, Han J, Nemeroff CB, Vale W. The BE (2)-M17 Neuroblastoma Cell Secretes Corticotropin-Releasing Factor and Is Responsive to Forskolin. Brain Research 1994; 654:159-162.

12. Kasckow JW, Mulcahey J, Han J, Owens MJ, Nemeroff CB. Interleukin 1α Induces Corticotropin-Releasing Factor Secretion and Synthesis from NPLC-KC Cells through Various Second Messenger Pathways. 1994; Synapse 18:354-358.

13. Owens MJ, Mulchahey JJ, Kasckow JW, Plotsky PM, Nemeroff CB. Exposure to an antisense oligonucleotide decreases corticotropin-releasing factor receptor binding in rat pituitary cultures. Journal of Neurochemistry, 1995; 64:2358-2361.

14. Kasckow JW, Han J, Mulcahey JJ, Owens MJ, Risby ED, Fisher J, Nemeroff CB. Regulation of Corticotropin-Releasing Factor Secretion and Synthesis in the Human Neuroblastoma Clones-BE (2)-M17 and BE (2)-C. 1995; Journal of Neuroendocrinology. 7:461-466.

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15. Swofford CD, Kasckow JW, Scheller-Gilkey G, Inderbitzen LB. Substance use: A powerful predictor of relapse in schizophrenia. Schizophrenia Research 1996; 20:145-151.

16. Kasckow JW, McElroy SL, Cameron RL, Mahler LL, Fudala SJ. The Use of Divalproex in the Treatment of Behavioral Agitation in Elderly Patients with Dementia: Assessment with the BEHAVE-AD and CGI. Current Therapeutic Research 1997; 58: 981-989.

17. Kasckow JW, Regmi A, Gill PS, Parkes DG, Geracioti TD. Regulation of Corticotropin-Releasing Factor (CRF) Messenger RNA and CRF Peptide in the Amygdala: Studies in Primary Amygdalar Cultures. Endocrinology 1997; 138: 4774-4782.

18. Geracioti TD, Loosen PT, Ekhator NN, Schmidt D, Chambliss B, Baker DG, Kasckow JW, Richtand NM, Keck PE, Ebert MH. Uncoupling of Serotonergic and Noradrenergic Systems in Depression: Preliminary Evidence from Continuous Cerebrospinal Fluid Sampling. Depression and Anxiety. 1997; 6:89-94.

19. Gill PS, Regmi A, Porter-Gill PA, Kasckow JW. Interleukin-1 Regulation of Corticotropin-Releasing Factor (CRF), Glucocorticoid Receptor, c-Fos and c-Jun Messenger RNA in the NPL-KC Cell Line. Molecular and Cellular Endocrinology 1998; 137: 31-39.

20. Chance WT, Sheriff S, Kasckow JW, Regmi A, Balasubramaniam A. NPY Messenger RNA is Increased in Medial Hypothalamus of Anorectic Tumor-Bearing Rats. Regulatory Peptides. 1998; 75-76:347-353.

21. Sheriff S, Dayal R, Kasckow JW, Regmi A, Chance W, Fischer J, Balasubramaniam. NPY Upregulates Genes Containing CRE Element in Human Neuroblastoma Cell Lines Bearing Y-1 and Y-2 Receptors: Involvement of CREB. Regulatory Peptides 1998; 75-76: 309-318.

22. Mulchahey JJ, Regmi A, Sheriff S, Balasubramaniam, Kasckow JW. Coordinate and Divergent Regulation of Corticotropin-Releasing Factor and Corticotropin-Releasing Factor-Binding Protein Expression in an Immortalized Amygdalar Neuronal Cell Line. Endocrinology 1999; 140: 251-259.

23. Mulchahey JJ, Kasckow JW, Plotsky PM, Hauger RL. Steroidal Regulation of Portal Arginine-Vasopresiin Levels in Aged Fischer 344 Rats. Brain Research 1999; 822:243-245.

24. Kasckow JW, Regmi A, Mulchahey JJ, Plotsky PM, Hauger RL. Changes in Brain Corticotropin-Releasing Factor Messenger RNA Expression in Aged Fischer 344 Rats. Brain Research 1999; 822: 228-230.

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25. Kasckow JW, Regmi A, Sheriff S, Mulchahey JJ, Geracioti TD Regulation of Corticotropin-Releasing Factor Messenger RNA by Nicotine in an Immortalized Amygdalar Cell Line. Life Sciences 1999; 65: 2709-2714.

26. Kasckow JW, Regmi A, Seasholtz AF, Mulchahey JJ. Regulation of Corticotropin-Releasing Factor-Binding Protein Expression in Amygdalar Neuronal Cultures. Journal of Neuroendocrinology 1999; 11: 959-966.

27. Baker DG, West SA, Nicholson WE, Ekhator NN, Kasckow JW, Hill KK, Bruce AB, Somoza EC, Prth DN, Geracioti TD. Serial Corticotropin-Releasing Hormone Levels and Adrenocortical Activity in Combat Veterans with Posttraumatic Stress Disorder. American Journal of Psychiatry 1999; 156: 585-588.

28. Madhusoodanan S, Brecher M, Brenner R, Kasckow JW, Kunik M, Negron A, Pomara N. Risperidone in the Treatment of Elderly Patients with Psychotic Disorders. American Journal of Geriatric Psychiatry 1999; 7: 132-138.

29. Mulchahey JJ, Malik MS, Sabai M, Kasckow JW. Serotonin Selective Reuptake Inhibitors in the Treatment of Geriatric Depression and Related Disorders. International Journal of Neuropsychopharmacology 1999; 2: 121-127.

30. Mulchahey JJ, Ekhator N, Zhang H, Kasckow JW, Baker D, Geracioti T. Cerebrospinal Fluid and Plasma Testosterone Levels in Post-traumatic Stress Disorder and Tobacco Dependence. Psychoneuroendocrinology 2001; 26:273-285.

31. Kasckow JW, Sabai M, Malik MS, Pisarska M, Mulchahey JJ. Treating Behavioral Disturbance in Dementia: Pharmacoeconomic Considerations. Federal Practitioner July 2000: 34-41.

32. Pisarska M, Mulchahey JJ, Welge J, Geracioti TD, Kasckow JW. Age-Related Alterations in Emotional Behaviors and Amygdalar Corticotropin-Releasing Factor (CRF) and CRF-Binding Protein Expression in Aged Fischer 344 Rats. Brain Research 2000; 877:184-190.

33. Kasckow JW, Hagan M, Mulchahey JJ, Baker DG, Ekhator NN, Strawn JR, Nicholson W, Orth DN, Loosen PT and Geracioti Jr, TD. The Effect of Feeding on Cerebrospinal Fluid Corticotropin-Releasing Hormone Levels in Humans. Brain Research 2001; 904: 218-224.

34. Kasckow JW, Twamley E, Mulchahey JJ, Carroll B, M. Sabai M, Strakowski SM, Patterson T, Jeste DV. Chronically Hospitalized Patients with Schizophrenia: Health-related Quality of Well-Being and Comparison with Matched Outpatients. Psychiatry Research 2001;103: 69-78.

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35. Kasckow JW, Lupien SJ, Behan DP, Welge J, Hauger RJ. Circulating human corticotropin-releasing factor-binding protein levels following cortisol infusions. Life Sciences 2001; 69: 133-142.

36. Janicak PG, Keck PE, Davis JM, Kasckow JW, Tugrul K, Dowd SM, Strong J, Sharma RP, Strakowski SM. A Double-Blind, Randomized, Prospective Evaluation of the Efficacy and Safety of Risperidone versus Haloperidol in the Treatment of Schizoaffective Disorder. J Clin Psychopharmacol 2001; 21:360-8.

37. Geracioti TD, Baker DG, Ekhator NN, West SA, Hill KK, Bruce AB, Schmidt D, Rounds-Kugler B, Yehuda R, Keck PE, Kasckow JW. Cerebrospinal Fluid Norepinephrine Concentrations in Post-Traumatic Stress Disorder. Am J Psychiatry 2001; 158:1227-30.

38. Kasckow JW, Mohamed S, Thallasinos A, Carroll B, Zisook S, Jeste D.. Antidepressant Augmentation of Antipsychotic Treatment in Older Schizophrenia Patients. International Journal of Geriatric Psychiatry 2001; 16: 1163-1167.

39. Baker DG, Ekhator NN, Kasckow JW, Hill KK, Zoumakis E, Dashevsky BA, Chrousos GP, Geracioti TD. Plasma and Cerebrospinal Fluid Interleukin-6 Concentrations in Posttraumatic Stress Disorder. Neuroimmunomodulation 2001; 9: 209-217.

40. Sheriff S, Dautzenberg FM, Mulchahey JJ, Pisarska M, Hauger RL, Chance WT, Balasubramaniam A, Kasckow JW. Interaction of Neuropeptide Y and Corticotropin-Releasing Hormone Signaling Pathways in AR-5 Amygdalar Cells. Peptides 2001; 22: 2083-2089.

41. Kasckow JW, Thalassinos A, Carroll BT. Citalopram Treatment of Minor Depression in Elderly Men: An Open Pilot Study. American Journal of Geriatric Psychiatry 2002; 10: 344-347.

42. Sheriff S, Qureshy AF, Chance WT, Kasckow JW, Balasubramaniam A. Predominant role by CaM kinase in NPY Y1 receptor signaling: Involvement of CREB. Peptides 2002; 23:87-96.

43. Nikodemova M, Kasckow JW, Manganiello V, Aguilera G. Cyclic Adenosine Monophosphate Regulation of CRH Promoter Activity in AtT-20 Cells and in a Transformed Hypothalamic Cell. Endocrinology 2003; 144: 1292-1300.

44. Sheriff S, Chance WT, Iqbal S, Rizvi TA, Xiao C, Kasckow JW, Balasubramaniam A. Hypothalamic administration of camp agonist/PKA activator inhibits both schedule feeding and NPY-induced feeding in rats. Peptides 2003; 24:245-254.

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45. Kasckow JW, Mulchahey JJ, Aguilera G ,Pisarska M, Nikodemova Chia Chen H, M, Herman JP, Murphy EK, Liu Y, Rizvi TA, Dautzenberg FM, Sheriff S. Corticotropin-Releasing Hormone (CRH) Expression and Protein Kinase A Mediated CRH Receptor Signaling in an Immortalized Hypothalamic Cell Line Journal of Neuroendocrinology 2003; 15:521-529.

46. Kasckow JW, Mulchahey JJ, Geracioti TD. Effects of the vanilloid agonist olvanil and antagonist capsazepine on rat behaviors. Progress in Neuro-psychopharmacology and Biological Psychiatry. 2004; 28: 291-295.

47. Depp CA, Jin H, Mohamed S, Kasckow JW, Moore D, Jeste D. Bipolar Disorder in Middle Aged and Elderly Adults: Is Age of Onset Important? J Nerv Mental Dis 2004; 192:796-799.

48. Kasckow JW, Segar TM, Xiao C, Furay AR, Evanson NK, Ostrander MM, Herman JP. Stability of Neuroendocrine and Behavioral Responsiveness in Aging Fischer 344/Brown-Norway Hybrid Rats. Endocrinology. 2005;146: 3105-3012.

49. Lee, R, Geracioti TD, Kasckow JW, Cooper TB, Coccaro EF. Childhood Trauma and Personality Disorder: Positive Correlation with CSF Corticotropin-Releasing Factor in Adulthood. Am J Psychiatry 2005; 162: 995-997.

50. Baker DG, Ekhator NN, Kasckow JW, Dashevsky B, Horn PS, Bednarik L, Geracioti TD. Increased Basal Serial Cerebrospinal Fluid Cortisol in Combat Veterans with Post Traumatic Stress Disorder. Am J Psychiatry 2005; 162:992-4.

51. Mohamed S, Bondi MW, Kasckow JW, Golshan S, Jeste DV. Neurocognitive Functioning in Dually Diagnosed Middle Aged and Elderly Patients with Alcoholism and Schizophrenia. International Journal of Geriatric Psychiatry. 2006; 21: 711-718.

52. Xiao C, Sartin JL, Mulchahey JJ, Segar TM, Sheriff S, Herman JP, Kasckow JW. Aging Associated Changes in Amygdalar CRH and CRH-BP in Fischer 344 Rats. Brain Research 2006; 1073-1074:325-31.

53. Zisook S, Nyer M, Kasckow JW, Golshan S, Lehman D, Montross L. Depressive symptom patterns in patients with chronic schizophrenia and subsyndromal depression. Schizophr Res. 2006; 86:226-33.

54. Lee RJ, Gollan J, Kasckow JW, Geracioti T, Coccaro EF. CSF Corticotropin-Releasing Factor in Personality Disorder: Relationship with Self-Reported Parental Care. Neuropsychopharmacology. 2006; 31:2289- 2295.

55. Mohamed S, Osatuke K, Aslam M, Kasckow JW. Treatment of Co-Morbid Depression and Anxiety in the Elderly with Escitalopram: A 12 Week Open Label Trial. American Journal of Geriatric Pharmacotherapy 2006; 4: 201-209.

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56. Coccaro EF, Beresford B, Minar P, Kasckow JW, Geracioti T. CSF testosterone: Relationship to aggression, impulsivity, and venturesomeness in adult males with personality disorder. J Psychiatr Res. 2007; 41(6):488-92.

57. Kageyama K, Hanada K, Iwasaki Y, Sakihara S, Nigawara T, Kasckow J, Suda T. Pituitary adenylate cyclase-activating polypeptide stimulates corticotrophin-releasing factor, vasopressin and interleukin-6 gene transcription in hypothalamic 4B cells. J Endocrinology 2007; 195: 199-211.

58. Kasckow J, Montross L, Golshan S, Mohamed S, Patterson T, Sollanzano E, Zisook S. Suicidality in Middle Aged and Older Patients with Schizophrenia and Depressive Symptoms: Relationship to Functioning and Quality of Life. International Journal of Geriatric Psychiatry 2007;22: 1223-1228.

59. Napier KK, Barrett JJ, Hart KJ, Mullins M, Schmerler JT, Kasckow JW. Judgements of Financial Abilities of Severely Mentally Ill Individuals: A Comparison of Self-Report and an Objective Measure. Psychiatry, Psychology and the Law 2007; 14, 315-326.

60. Geracioti TD Jr, Baker DG, Kasckow JW, Strawn JR, Jeffrey Mulchahey J, Dashevsky BA, Horn PS, Ekhator NN.. Effects of trauma-related audiovisual stimulation on cerebrospinal fluid norepinephrine and corticotropin-releasing hormone concentrations in post-traumatic stress disorder. Psychoneuroendocrinology. 2008, 33:416-24.

61. Roseman AS; Kasckow J, Fellows I;Osatuke K; Patterson T, Mohamed S, Zisook S Insight, Quality of Life, and Functional Capacity in Middle-Aged and Older Adults with Schizophrenia. International Journal of Geriatric Psychiatry 2008; 23:760-5.

62. Ogura E, Kageyama K, Hanada K, Kasckow J, Suda T. Effects of estradiol of corticotropin-releasing factor gene and interleukin-6 production via estrogen receptor type beta in hypothalamic 4B cells. 2008 Peptides 29:456-64.

63. Kasckow JW, Patterson T, Fellows I, Golshan S, Solorzano E, Mohamed S, Zisook S. Functioning in Middle Aged and Older Patients with Schizophrenia and Depressive Symptoms: Relationship to Psychopathology. American Journal of Geriatric Psychiatry 16:660-3, 2008.

64. Montross LP, Kasckow JW, Golshan S, Solorzano E, Lehman D, Zisook S. Suicidal ideation and suicide attempts among older patients with schizophrenia-spectrum disorders and subsyndromal depression. Journal of Nervous and Mental Diseases 196:884-90, 2008.

65. Zisook S, Kasckow J, Golshan S, Fellows I, Sollarzano E, Lehman D, Mohamed S, Jeste D. Citalopram Augmentation for Subsyndromal Depressive Symptoms in Middle-Aged and Older Patients with Schizophrenia and Schizoaffective Disorder: A Randomized Controlled Trial. J Clin Psychiatry 70:562-571, 2009.

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66. Segar T, Kasckow JW, Welge J, Herman JP. Heterogeneity of Neuroendocrine Stress Responses in Aging Rat Strains. Physiology and Behavior 96: 6-11, 2009.

67. Barr CS, Dvoskin RL, Gupte M, Sommer W, Sun H, Schwandt ML, Lindell SG, Kasckow JW, Suomi SJ, Goldman D, Higley JD, Heilig M. Functional CRH variation increases stress-induced alcohol consumption in primates. Proc Natl Acad Sci USA. 106(34):14593-8, 2009.

68. Kasckow JW, Xiao C, Herman JP. Glial glucocorticoid receptors in aged Fisher 344 (F344) and F344/Brown Norway rats. Experimental Gerontology 44:335-43, 2009.

69. Kasckow JW, Lanouette N, Patterson T, Fellows I, Golshan S, Solorzano E, Zisook S. Treatment of Subsyndromal Depressive Symptoms in Middle-Age and Older Adults with Schizophrenia: Effect on Functioning. International Journal of Geriatric Psychiatry 25: 183-190, 2010.

70. Nyer M, Kasckow J, Fellows I, Lawrence EC, Golshan S, Solorzano E, Zisook S. The relationship of marital status and clinical characteristics in middle-aged and older patients with schizophrenia and depressive symptoms. Annals of Clinical Psychiatry 22(3):172-9, 2010.

71. Kasckow JW, Fellows I, Golshan S, Solorzano E, Meeks T, Zisook. Treatment of Subsyndromal Depressive Symptoms in Middle-Age and Older Patients with Schizophrena: Effect of Age on Response. American Journal of Geriatric Psychiatry 18: 853-857, 2010.

72. Zisook S, Kasckow JW, Golshan S, Fellows I, Lanouette N, Vahia I, Mohamed S, Rao S. Augmentation with citalopram for suicidal ideation in middle-aged and older outpatients with schizophrenia and schizoaffective disorder who have subthreshold depressive symptoms: a randomized controlled trial. Journal of Clinical Psychiatry 71:915-22, 2010.

73. Kasckow J, Brown C, Morse J, Karpov I, Bensasi S, Thomas S, Ford A, Reynolds C. Racial Preferences for Participation in a Depression Prevention Trial Involving Problem Solving Therapy. Psychiatric Services 61(7):722-4.

74. Kasckow J, Liu N, Haas G, Phillips M. Case-Control Study of the Relationship of Depressive Symptoms to Suicide in a Community-Based Sample of Individuals with Schizophrenia in China. Schizophrenia Research 122: 226-231, 2010.

75. Lindell S, Schwandt M,Sun H, Sparenborg J, Bjoerk K, Kasckow J, Sommer W, Goldman D, Higley J, Suomi, S, Heilig M, Barr C. Functional NPY variation as a factor in stress resilience and alcohol consumption in rhesus macaques. Archives of General Psychiatry 67(4):423-31, 2010.

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76. Kasckow J, Ingram E, Tew J, Brown C, Conner K, Morse J, Haas G, Reynolds C, Oslin D. Differences in Treatment Attitudes Between Depressed African American and Caucasian Primary Care Veterans. Psychiatric Services 62: 426-429, 2011.

77. Osatuke K, Reid M, Stiles WB, Kasckow JW, Zisook S, Mohamed S. Narrative evolution and assimilation of problematic experiences in a case of pharmacotherapy for schizophrenia. Psychotherapy Research. 21:41-53, 2011.

78. Dawes S, Palmer B, Meeks T, Golshan S, Kasckow J, Mohamed S, Zisook S. Does antidepressant treatment improve cognition in older persons with schizophrenia or schizoaffective disorder and comorbid subsyndromal depression? Neuropsychobiology 65:168-72, 2012.

79. Kasckow J, Liu N, Phillips M. Case-Control Study of the Relationship of Functioning to Suicide in a Community-Based Sample of Individuals with Schizophrenia in China. Community Mental Health Journal. 48: 317-320, 2012.

80. Kasckow J, Brown C, Morse J, Begley A, Bensasi S, Reynolds C. Post Traumatic Stress Disorder Symptoms in Emotionally Distressed Individuals Referred for a Depression Prevention Intervention: Relationship to Problem Solving Skills. International Journal of Geriatric Psychiatry 27:1106-11, 2012.

81. Kasckow J, Appelt C, Haas G, Huegel S, Fox L, Gurklis J, Zickmund S, Daley D. Development of a Recovery Manual for Suicidal Patients with Schizophrenia: Consumer Feedback. Community Mental Health Journal 48:564-7, 2012.

82. Kasckow JW, Karp JF, Whyte E, Butters M, Brown C, Begley A, Bensasi S, Reynolds CF 3rd. Subsyndromal depression and anxiety in older adults: Health related, functional, cognitive and diagnostic implications. J Psychiatric Research 47: 599-603, 2013.

83. Kasckow J, Golshan S, Zisook S. Does Age Moderate the Relationship between Depressive Symptoms and Suicidal Ideation in Middle Aged and Older Patients with Schizophrenia and Subthreshold Depression?" American Journal of Geriatric Psychiatry 2013. Feb 6. Epub ahead of print.

84. Kasckow J, Zickmund S, Rotondi A, Mrkva A, Gurklis J, Chinman M, Fox L, Loganathan M, Hanusa B, Haas G. Development of Telehealth Dialogues for Monitoring Suicidal Patients with Schizophrenia: Consumer Feedback. Community Mental Health Journal 2013 Jan 10. Epub ahead of print.

85. Vahia I, Lanoutte NM, Golshan S, Fellows I, Mohamed S, Kasckow JW. Adding antidepressants to antipsychotics for treatment of subsyndromal depressive symptoms in schizophrenia: Impact on positive and negative symptoms. Indian Journal of Psychiatry. 55:144-8, 2013.

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86. Cornelius J, Haas GL, Appelt CJ, Walker J, Fox L, Kasckow JW, Luther JF,

Salloum IM. Suicidal ideation associated with PCL checklist-ascertained PTSD among

veterans treated for substance abuse. International Journal of Medical and Biological

Frontiers. 18:1-11, 2013.

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Reviews, invited published papers, proceedings of conference and symposia, monographs, books and book chapters

1. Kasckow JW and Nemeroff CB. Peptidergic Alterations in Stress. In: Westengarten H, Den Boer JA, Murphy DL, editors. Advances in the Neurobiology of Anxiety Disorders, Chichester, UK: Wiley; 1996. p. 383-397.

2. McElroy SL, Kasckow JW, Lott AD, Keck PE. Valproate in the Treatment of Behavioral Agitation of Dementia. Psychiatric Annals 1996; 26(7): S474-S479.

3. Geracioti TD, Goldsmith J, Friedman LM, Norman AB, Somoza E, Kasckow JW, Baker DG, Richtand NM, Anthenelli RM, Keck PE. Cerebrospinal Fluid Neuroendocrinology of Alcohol Misusers. Addiction Biology 1997; 2:401-409.

4. Kasckow JW, Fudala SJ. Obsessive Compulsive Disorder in the Geriatric Population. International Journal of Geriatric Psychopharmacology 1997;1:27-33.

5. Mulchahey JJ, Malik MS, Sabai M, Kasckow JW. Serotonin Selective Reuptake Inhibitors in the Treatment of Geriatric Depression and Related Disorders. International Journal of Neuropsychopharmacology 1999; 2: 121-127.

6. Kasckow JW, Geracioti TD, Pisarska M, Regmi A, Baker D, Mulchahey JJ. The Hypothalamic-Pituitary-Adrenal Axis in Aging: Preclinical and Clinical Studies. In: M Morrison , Editor. Hormones and the Aging Brain. Cambridge, UK: Cambridge University Press; 2000. p. 37-52.

7. Pisarska M, Mulchahey JJ, Sheriff S, Geracioti TD, Kasckow JW. Regulation of corticotropin-releasing hormone in vitro. Peptides 2001; 22: 705-712.

8. Kasckow JW, Baker D, Geracioti TD. Corticotropin-releasing hormone in depression and post-traumatic stress disorder. Peptides 2001; 22: 845-851.

9. Kasckow JW. Cognitive Enhancers for Dementia: Do They Work? Current Psychiatry. 2002; 1(3): 23-28.

10. Kasckow JW, Geracioti TD. Neurohypophyseal Peptides: From Bench to Bedside. In: Pfaff D, Editor. Hormones, Brain and Behavior. London, England: Academic Press; 2002.p. 153-208.

11. Kasckow JW, Mulchahey JJ, Aslam M, Sabai M, Mohamed S. When and how to use SSRI’s to treat late-life depression. Current Psychiatry 2003; 2(1): 43-47.

12. Mohamed S, Kasckow JW, Zisook S, Jeste DV. Community-Based Treatment of Schizophrenia and other Severe Mental Illness. In: Cohen C, Editor Schizophrenia into

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Later Life Treatment, Research and Policy. Washington, D.C.: APA Press; 2003. p 205-222.

13. Kasckow JW, Mohamed S, Granholm E, Jeste DV. Use of Novel Antipsychotics in Older Patients with Schizophrenia. In: Cohen C, Editor. Schizophrenia into Later Life Treatment, Research and Policy. Washington, D.C.: APA Press; 2003, p. 195-204.

14. Baker DG, Geracioti TD, Kasckow JW, Zoumakis E, Chrousos GP. Cytokines and PTSD. In: Z Kronfol, Editor. Cytokines and Mental Health. .Dordrecht: Kluver Academic Publishers; 2003, p. 201-206.

15. Kasckow JW, Aguilera G, Mulchahey JJ, Sheriff S, Herman JP. In vitro Regulation of Corticotropin Releasing Hormone Life Sciences 2003; 9424, 1-14.

16. Montross L, Mohamed S, Kasckow JW, Zisook S. Preventing late-life suicide: 6 steps to detect the warning signs. Current Psychiatry 2003; 2(8):15-26.

17. Kahn S, Kasckow JW, Mulchahey JJ, Mohamed S. Antipsychotic Use in the Older Patient with Schizophrenia. Behavioral Health Management March 2004; 24:S1-S4.

18. Kasckow JW, Mulchahey JJ, Mohamed S. Using Antipsychotics to Manage Agitation in Patients with Dementia. Current Psychiatry 2004; 3(2):55-64.

19. Kasckow JW, Mulchahey JJ, Mohamed S The Use of Novel Antipsychotics in the Older patient with Neurodegenerative Disorders in the Long Term Care Setting. JAMDA 2004; 5:242-8.

20. Kasckow JW, Mulchahey JJ, Mohamed S. Using Antipsychotics in Patients with Dementia. Current Psychiatry in Primary Care 2005; 1: 31-39.

21. Owens G, Baker D, Kasckow JW, Mohamed S. PTSD in the Elderly Population. International Journal of Geriatric Psychiatry 2005; 20: 1118-1130.

22. Montross L, Zisook S, Kasckow JW. Suicide Among Patients with Schizophrenia: A Consideration of Risk and Protective Factors. Annals of Clinical Psychiatry 2005;17:173-82.

23. Osatuke K, Kasckow JW, Mohamed S. Later Life Schizophrenia. In: D Fujii and I Ahmed, editors. The Spectrum of Psychotic Disorders: Neurobiology, Etiology & Pathogenesis. Cambridge University Press: Cambridge, UK. 2007. p 59-77.

24. Montross L, Zisook S, Kasckow JW. Awareness of illness and suicide risk. In: R Tatarelli, M Pompili and P Girardi, editors. Suicide and Schizophrenia Nova Biomedical Books: New York.

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25. Zisook S, Montross L, Kasckow J, Mohamed S, Palmer B, Patterson T, Golshan S, Fellows I, Lehman D, Sollanzano E. Subsyndromal Depressive Symptoms in Middle Aged and Older Patients with Schizophrenia. American Journal of Geriatric Psychiatry15:1005-14, 2007.

26. Osatuke K, Ciesla J, Kasckow JW, Zisook S, Mohamed S. Insight in Schizophrenia: A Review of Etiological Models and Supporting Research. Comprehensive Psychiatry 49: 70-77, 2008.

27.Kasckow JW, Zisook S Co-occurring Depressive Symptoms in the Older Patient with Schizophrenia Drugs and Aging 25: 631-647, 2008.

28. Sriwattanakomen R, Ford A, Thomas S, Miller M, Stack J, Morse J, Kasckow J, Brown C, Reynolds C. D Preventing Depression in Later Life: Translation from Concept to Experimental Design and Pilot Implementation. American Journal of Geriatric Psychiatry 16: 460 – 468, 2008.

29. Geracioti TD, Strawn JR, Ekhator NN, Wortman M, Kasckow JW. Neuropeptides of Central Nervous System Origin: From Bench to Bedside. In: D. Pfaff, A Arnold, A Etgen, S Fahrback, and R. Rubin, eds Hormones, Brain, and Behavior, 2nd Edition, Academic Press, San Diego, CA, 2009.

30. Felmet K, Zisook S, Kasckow J. Elderly Patients with Schizophrenia and Depression: Diagnosis and Treatment. Clinical Schizophrenia & Related Psychoses 4:239-250, 2011.

31. Kasckow J, Felmet K, Zisook S. Managing Suicide Risk in Patients with Schizophrenia. CNS Drugs 25: 129-143, 2011.

32. Kasckow J, Montross L, Prunty L, Fox L, Zisook S. Suicidal Behavior in the OIder Patient with Schizophrenia. Aging Health. 7: 337-339, 2011.

33. Kasckow J, Felmet K, Appelt C, Thompson R, Rotondi A, Haas G. Telepsychiatry in the Assessment and Treatment of Schizophrenia. Clinical Schizophrenia & Related Psychoses (in press).

34. Cornelius JR, Haas GL, Appelt CJ, Walker JD, Fox LJ, Kasckow JW, Luther JF, Salloum IM. Suicidal Ideation Associated with PCL Checklist-Ascertained PTSD among Veterans Treated for Substance Abuse, in the book Post-Traumatic Stress Disorder: New Research, Nova Science Publishers, Inc. (in press).

35. Myers B, Dolgas M, Xiao C, Kasckow J, Cullinan W, Herman JP. Central stress-integrative circuits: Forebrain glutamatergic and GABAergic projections to the dorsomedial hypothalamus, medial preoptic area, and bed nucleus of the stria terminalis. Brain Structure and Function (in press).

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Other Publications

1. Kasckow JW and Maltbie A. Conversion Hallucinosis in a Patient with Pseudohypoparathyroidism. Jefferson Journal of Psychiatry 1989; 7(2):30-35.

2. Kasckow JW, Dolor R and Lipper S. Delayed Onset of Neuroleptic Malignant Syndrome after Discontinuation of Thioridazine. Journal of Clinical Psychopharmacology 1990; 10:146.

3.Kasckow JW, Lee J, Wingfield M. Psychiatric Manifestations of the Haw River Syndrome. Ursus Medicus 1991; 1:21-23.

4. Osatuke K, Reid M, Stiles W, Kasckow JW, Zisook S, Mohamed S. Narrative evolution and assimilation of problematic experiences in a case of pharmacotherapy for schizophrenia. Psychotherapy Research 15: 1-13, 2010.

5. Kasckow J, Appelt C, Haas G, Huegel S, Fox L, Gurklis J, Daley D. Development of a recovery manual for suicidal patients with schizophrenia. Schizophrenia Research. 2011 May 19.

PRESENTATIONS AT SCIENTIFIC MEETINGS (WITH PUBLISHED ABSTRACTS)

1. Kasckow JW, Ziretta D, Herndon RM. Membrane Architecture of Central Myelinated Fibers in the Rat: A Freeze Fracture Study. Lake Ontario Regional Neuroscience Meeting, Rochester, New York, 1980.

2. Kasckow JW, Tabira T, Itoyama Y, Kuroiwa Y, Takenaka A, Nagai Y. Experimental Allergic Encephalomyelitis: Suppression with SD-170, a New Synthetic Drug. National Student Research Forum, Galveston, 1982.

3. Thomas GJ, Kasckow JW, Herndon RM. Performance Factors in Regard to Impaired Memory and Tolerance Induced by Atropine Sulfate. 1984 Society for Neuroscience Abstracts.

4. Kasckow JW, Abood LG, Hoss W, Herndon RM. Effects of Phospholipase A2 and Other Enzymes on Bullfrog Sciatic Nerve. 1984 Society for Neuroscience Abstracts.

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5. Kasckow JW, Abood LG, Hoss W, Herndon RM. 3H-Saxitoxin Binding and

Phosphorus Metabolism Changes Associated with Phospholipase A2-Induced Conduction Block. 1985 Society for Neuroscience Abstracts.

6. Kasckow JW, Goldblatt R, Reichman M, Herndon RM. Demyelinating Effects of Phospholipase A2 and Its Products in Rat Spinal Cord. 1986 Society for Neuroscience Abstracts.

7. Kasckow JW, Cain ST, Nemeroff CB. Cyclic AMP and Ca/Calmodulin Stimulated Protein Phosphorylation in Rat Cerebellum, Striatum and Hippocampus. 1989 Society for Neuroscience Abstracts.

8. Kasckow JW, Cain ST, Nemeroff CB. Neurotensin Incubation with Rat Neostriatal Slices: Effects on Calcium/Calmodulin Dependent Protein Phosphorylation. 1990 Society for Neuroscience Abstracts.

9. Kasckow JW, Bullock PN, Malek-Hedayat S, Rome LH. Cellular Slices: A System for Studying Myelination, 1991 Society for Neuroscience Abstracts.

10.Kasckow JW, Notterpek L, Rome LH. Anti-Galactocerebroside Induced Inhibition of Myelinogenesis in Cerebellar Slices: Ultrastructural Observations. Annual Meeting of the Society for Experimental Neuropathology, 1991.

11.Kasckow JW, Montmimy MM, Vale WW. Corticotropin Releasing Factor Gene Expression in JEG-3 Cells. 1992 Society for Neuroscience Abstracts.

12.Ericsson A, Liu C. Kasckow JW, Hart RP, Sawchenko PE. Distribution of the Type 1 Interleukin-1 Receptor mRNA in the Central Nervous System of the Rat. 1993 Society for Neuroscience Abstracts.

13.Plotsky P, Thrivikraman KV, Kasckow JW, Meaney MJ. Interactions between Molecular and Environmental Factors in Regulating CRH Neurons. Meeting of the American College of Neuropsychopharmacology, 1993

14.Kasckow JW, Owens MJ, Han J, Stipetic M, Nemeroff CB. The BE (2)-CNeuroblastoma Cell Secretes Corticotropin-Releasing Factor and is Responsive to Forskolin. Society for Biological Psychiatry Meeting, 1994, Philadelphia, PA.

15.Kasckow JW, Owens MJ, Han J, Stipetic MD, Vale W, Nemeroff CB. The BE (2)-M17 Human Neuroblastoma Cell Line Synthesizes and Secretes Corticotropin-Releasing Factor. 1994 Endocrine Society Meeting, Anaheim, CA.

16.Kasckow JW, Mulcahey J, Han J, Owens MJ, Stipetic MD, Breitman D, Nemeroff CB. Interleukin 1 a Induces Corticotropin-Releasing Factor Secretion and Synthesis from NPLC-KC Cells through Various Second Messenger Pathways. 1994 Society for Neuroscience Abstracts.

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17.Owens MJ, Mulcahey JJ, Kasckow JW, Plotsky PM, Nemeroff CB. Exposure to a CRF Receptor Antisense Oligonucleotide Decreases CRF Receptor Binding in vitro. 1994 Society for Neuroscience Abstracts.

18.Kasckow JW, Risch SC, Swoford C, Inderbitzen LI. Lack of Correlations of Plasma HVA Levels with Neuroleptic Dose and Psychotic Severity in a Naturalistic Setting. Society for Biological Psychiatry Meeting, 1995, Miami, FL.

19.Hans J, Kasckow JW, Parkes DG, Muldhahey JJ, Breitman D, Kazanjian CH, Owens MJ, Nemeroff CB. Regulation of CRF in BE (2)-M17 and BE (2)-C Neuroblastoma Cell Lines. Society for Biological Psychiatry Meeting, 1995, Miami, FL.

20.Owens MJ, Mulcahey JJ, Owens CA, Stout S, Thrivikraman KV, Plotsky PM, Kasckow JW, Kilts CD, Stowe ZN, Plott SJ, Nemeroff CB. Corticotropin-Releasing Factor: New Studies and Clinical Implications. American Society for Neurochemistry Meeting, 1995.

21.Kasckow JW, Mulchahey JJ, Parkes DG, Kilts CD, Lambert P, Owens MJ, Risby ED, Stipetic MD, Nemeroff CB. Dexamethasone Does Not Alter Corticotropin-Releasing Factor (CRF) Produced by Rat Amygdaloid Neurons in Culture. 1995 Society for Neuroscience Abstracts.

22.Gill PS, Kasckow JW, Richtand NM, Porter-Gill PA, Geracioti TD. Interleukin 1 Regulation of Corticotropin-Releasing Factor (CRF) Messenger RNA Levels in the NPLC-KC Hepatoma Cell. 1996 International Endocrine Society Meetings, San Francisco, CA.

23.Kasckow JW, Gill PS, Parkes DG, Geracioti TD. Regulation of Corticotropin-Releasing Factor (CRF) Messenger RNA Levels in the BE (2)-M17 Neuroblastoma Cell Line by Protein Kinase A and C Activators. 1996 International Endocrine Society Meetings, San Francisco, CA.

24.Geracioti TD, Loosen P, Ekhator N, Schmidt D, Baker D, Richtand N, Kasckow J, Keck P, Ebert M. Uncoupling of CNS Serotonin and Norepinephrine Systems in Depression. 1996 Society for Biological Psychiatry Meeting.

25.Negron AE, Brenner R, Jeste D, Kasckow JW, Kunik M, Madhusoodan S, Pomara N Safety and Tolerability of Risperidone in Elderly Patients with Psychotic Disorders. 1997 American Association of Geriatric Psychiatry Annual Meeting, Orlando, FL.

26.Kasckow JW, McElroy S, Cameron R, Mahler L. Valproate in the Treatment of Agitation in Elderly Patients with Dementia. 1997 American Association of Geriatric Psychiatry Annual Meeting, Orlando, FL.

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27.Gill PS, Regmi A, Porter-Gill P, Aslam M, Kasckow JW. Interleukin-1 Regulation of Corticotropin-Releasing Factor (CRF), Glucocorticoid Receptor, c-Fos and c-Jun Messenger RNA in the NPL-KC Cell Line.1997 Endocrine Society Meeting, Minneapolis, MN.

28.Regmi A, Gill PS, Sheriff S, Kasckow JW. Expression of Corticotropin-Releasing Factor (CRF) Messenger RNA (mRNA) and Peptide in Immortalized Amygdalar Cells. 1997 Endocrine Society Meeting, Minneapolis, MN.

29.Kasckow JW, Regmi A, Aslam M, PS Gill PS. Expression of Corticotropin-Releasing Factor (CRF) Messenger RNA (mRNA) and CRF Peptide in Primary Amygdalar Cultures. 1997 Endocrine Society Meeting, Minneapolis, MN.

30.Sheriff S, Gill P, Regmi A, Kasckow JW, Taylor J. NPY Regulates Gene Transcription through cyclic AMP Response Element Binding Proteins in Human Neuroblatoma Cell Line.1997 Society for Neuroscience Abstracts.

31.Mulchahey JJ, Regmi A, Kasckow JW. Regulation of Corticotropin-Releasing Factor (CRF) Messenger RNA (mRNA) and Peptide in the Amygdala: Effects of Interleukins in Primary Neuronal Cultures. International Symposium in Psychoneuroendocrine and Immunological Correlates of Aging, Pavia, Italy, 1997.

32.Kasckow JW, Plotsky PM, Regmi A, Mulchahey JJ, Hauger RL. Age-Related Alteration in Corticotropin-Releasing Factor (CRF) Expression in Discrete Loci of the Rat Brain. 1998 American Association of Geriatric Psychiatry Annual Meeting, New Orleans, LA

33.Baker DG, West SA, Nicholson WE, Ekhator NN, Kasckow JW, Hill KK, Bruce AB, Somoza EC, Orth DN, Geracioti. Corticotropin-Releasing Hormone Levels and Adrenocortical Activity in Combat Veterans with Posttraumatic stress Disorder. 1998 International Society of Psychoneuroendocrinology Abstracts, Trier, Germany.

34.Mulchahey JJ, Regmi A, Clouse K, Kasckow JW, Hauger RL, Plotsky PM. Changes in Brain Corticotropin-Releasing Factor Messenger RNA Expression in Aged Fisher 344 Rats. 1998 Endocrine Society Meeting, New Orleans, LA.

35.Regmi A, Mulchahey JJ, Kasckow JW. Regulation of Corticotropin-Releasing Factor-Binding Protein (CRF-BP) Messenger RNA (mRNA) and Peptide in Immortalized Amygdalar Neuronal Cells. 1998 Endocrine Society Meeting, New Orleans, LA.

36.Mulchahey JJ, Regmi A, Kasckow JW. Expression of Corticotropin-Releasing Factor and its Binding-Protein by an Amygdalar Neuronal Cell Line. 2nd World Congress on Stress. Melbourne, Australia, 1998.

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37.Kasckow JW, Mulchahey JJ, Strakowski S, Thangavelu R, Rockwell E, Patterson T, Jeste D. Characteristics of Older Chronically Hospitalized Patients with Schizophrenia 1999 American Association for Geriatric Psychiatry Annual Meeting. In the Symposium: Schizophrenia in Later Life: Recent Advances, co-chairs: Kasckow JW, Jeste D, New Orleans, LA.

38.Kasckow JW, Carroll B, Rockwell E, Patterson T, Mulchahey JJ, Strakowski S, Jeste D. Chronically Hospitalized Inpatients with Schizophrenia: Psychopathologic, Cognitive and Functional Assessments. 1999 American Psychiatric Association, Washington D.C.

39.Janicak P, Keck PE, Davis J, Kasckow JW, Tugrul K, Dowd S, Sharma RP. Risperidone versus Haloperidol for Schizoaffective Disorder. 1999 American Psychiatric Association, Washington D.C.

40.Mulchahey JJ, Regmi A, Seasholtz AF, Kasckow JW. Regulation of Corticotropin-Releasing Factor-Binding Protein Messenger RNA (mRNA) and Protein in Primary Amygdalar Cultures, 1999 Endocrine Society Meeting, San Diego, CA.

41.Regmi A, Mulchahey JJ, Clouse K, Geracioti TD, Kasckow JW Nicotine Regulation of Corticotropin-Releasing Factor (CRF) Messenger RNA Levels in AR5 Amygdalar Cell Lines, 1999 Endocrine Society Meeting, San Diego, CA.

42.Pisarska M, Mulchahey JJ, Regmi A, Kasckow JW, Decrements in Amygdalar Corticotropin-Releasing Factor Messenger RNA Expression with Aging Parallels Changes in Emotional Behaviors, 1999 Endocrine Society Meeting, San Diego, CA.

43.Kasckow JW, Regmi A, Mulchahey JJ Regulation of Corticotropin-Releasing Factor in an Immortalized Hypothalamic Cell Line, 1999 Endocrine Society Meeting, San Diego, CA.

44.Mulchahey JJ, Ekhator N, Zhang H, West S, Keck P, Kasckow JW, Baker D, Geracioti TD. Cerebrospinal Fluid and Plasma Testosterone Levels in Post-Traumatic Stress Disorder and Tobacco Dependence. 1999 Meeting of the International Society for Psychoneuroendocrinology, Orlando, Fl.

45.Sheriff S, Mulchahey JJ, Regmi A, Chance WT, Balasubramaniam A, Kasckow JW. Corticotropin-Releasing Factor (CRF) Increases and Neuropeptide Y (NPY) Decreases, Cyclic Adenosine Monophosphate (cAMP) Production in the Immortalized CRF-Expressing AR-5 Neuronal Cell Line.1999 Society for Neuroscience Abstracts.

46.Regmi A, Mulchahey JJ, Kasckow JW. Glucocorticoid Regulation of Vasopressin (VP) and Corticotropin-Releasing Factor in an Immortalized Hypothalamic Cell Line. 1999 Society for Neuroscience Abstracts.

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47.Pisaraska M, Mulchahey JJ, Regmi A, Kasckow JW. Age-Dependent Changes in the Magnitude of Corticotropin-Releasing Factor (CRF) Expression and Behavioral Responses to Restraint in Fischer 344 Rats.1999 Society for Neuroscience Abstracts.

48.Kasckow JW, Regmi A, Sheriff S, Chance WT, Mulchahey JJ. Glucocorticoid Regulation of Corticotropin-Releasing Factor in an Immortalized Hypothalamic Cell Line. Neuropeptides at the Millenium Conference, Miami, Oct 1999.

49.Kasckow JW, Mulchahey JJ, Carroll B, Malik A, Patterson T, Bailey A, Jeste D. Chronically Hospitalized Older Patients with Schizophrenia: 6 Month Follow Up. 2000 American Association Annual Meeting, Miami, FL. In the symposium: Consortium for Research in Older People with Schizophrenia; Co-Chairs- Kasckow JW and Jeste D.

50.Kasckow JW, Mulchahey JJ. Preclinical Studies of Stress in Aging: Relevance toward Understanding Mood Disorders in Late Life. 2000 American Association Annual Meeting, Miami, FL. In the symposium: Stress in Aging: relationship to Disorders in Late Life. Chair- Kasckow JW

51.Sheriff S, Chance WT, Qureshy AF, Dayal R, Rizvi TA, Kasckow JW, Balasubramaniam B. Differential Hypothalamic Cyclic AMP Response by Obese Rats to Hunger and Satiety. 2000 Society for Neuroscience Abstracts.

52.Pisarska M, Mulchahey JJ, Sheriff S, Balasubramaniam B, Kasckow JW. Corticotropin-Releasing Factor Expression in Immortalized Amygdalar and Hypothalamic Cell Lines. 2000 Society for Neuroscience Abstracts.

53.Kasckow JW, Mulchahey JJ, Pisaraska M, Chance WT, Balasubramaniam B, Sheriff S. Corticotropin-Releasing Factor Receptor Signaling in Immortalized Amygdalar and Hypothalamic Cell Lines. 2000 Society for Neuroscience Abstracts.

54.Mulchahey JJ, Pisarska M, Welge J, Sherman L, Kasckow JW. Age Related Changes in Amygdalar Corticotropin-Releasing Factor Binding Protein Expression and Emotional Behaviors. Society for Neuroscience Abstracts 2000; 26: 1940.

55.Pisarska M, Mulchahey JJ, Welge J, Sherman L, Kasckow JW. Age Related Changes in Amygdalar Corticotropin-Releasing Factor Binding Protein Expression and Emotional Behaviors. 2000 International Congress of Endocrinology, Sydney, Australia.

56.Baker DG, Ekhator NN, Kasckow JW, Hill KK, Zoumakis E, Dashevsky BA, Chrousos GP, Geracioti TD. Plasma and Cerebrospinal Fluid Interleukin-6 Concentrations in Combat Veterans with Posttraumatic Stress Disorder. 2000 Society for Neuroscience Satellite Meeting on Cytokines and the Brain, New Orleans, LA.

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57.Thallasinos A, Carroll B, Kasckow JW. The Use of Citalopram to Treat Minor Depression in the Elderly. 2000 NCDEU Annual Meeting, Boca Raton, Fla.

58.Kasckow JW, Thallasinos A, Carroll B,. The Use of Citalopram to Treat Minor Depression in the Elderly. 2001 AAGP Annual Meeting, San Francisco, CA.

59.Kasckow JW, Thalassinos A, Carroll B, Zisook S, Jeste D. Antidepressant Augmentation of Antipsychotics in Chronically Hospitalized Inpatients with Schizophrenia. 2001 American Association Annual Meeting, San Francisco. In the symposium: Consortium for Research in Older People with Schizophrenia II; Co-Chairs- Kasckow JW and Jeste D.

60.Sheriff, S, Chance WT, Iqbal S, Rizvi TA, Quershy AF, Kasckow JW, Balasubramaniam A. Hypothalamic administration of PKA activator inhibits fasting and NPY-induced feeding in rats. NPY 2001 Meeting, Sydney Australia.

61.Sheriff, S, Chance WT, Iqbal S, Rizvi TA, Quershy AF, Kasckow JW, Balasubramaniam A. CAMP/PKA activator inhibits NPY, AGRP and schedule feeding-induced appetite signals in rats. 2001 Society for Neuroscience Abstracts.

62.M Pisarska, S Sheriff, F Dautzenberg, JJ Mulchahey, R Hauger, Kasckow JW. Corticotropin Releasing Hormone (CRH) and Neuropeptide Y (NPY) Receptor Messenger RNA Expression in AR-5 Cells. 2001 Society for Neuroscience Abstracts.

63.Kasckow JW, N Chowdry, M Pisarska, JJ Mulchahey, TD Geracioti, Jr. Effects of the Vanilloids Olvanil and Capsazepine on Elevated Plus Maze and Porsolt Swim Test Behaviors in Fisher 344 Rats. 2001 Society for Neuroscience Abstracts.

64.Kasckow JW, Mohamed S, Zisook S, Jeste DV. Depressive Symptoms in Older Adults with Schizophrenia. 2002 American Association Annual Meeting, Orlando, FL. In the symposium: Consortium for Research in Older People with Schizophrenia III; Co-Chairs- Kasckow JW and Jeste D.

65.Mohamed S, Jin H, Kasckow JW, Jeste D. Psychopathologic, Cognitive and Quality of Life Related Differences between Late Onset Bipolar vs. Unipolar Disorder. 2002 AAGP Annual Meeting, Orlando, Fla.

66.Mohamed, S., Bondi, M., Kasckow, JW, Jeste, D. Neurocognitive Functioning in Dually Diagnosed Patients with Alcoholism and Schizophrenia. 2002 AAGP Annual Meeting, Orlando, Fla.

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67.Nikodemova M, Kasckow J, Aguilera G. Regulation of Corticotropin-Releasing Hormone Transcription by cAMP in a Transformed Hypothalamic Cell Line and AtT20 Cells. 2002 Endocrine Society Abstracts.

68.Mohamed S, Kasckow JW, Zisook S, Jeste D. Depressive Symptoms in Older Adults with Schizophrenia. 2002 International Congress of Geriatric Neuropsychopharmacology (ICGP), Barcelona, Spain.

69.Nikodemova M, Kasckow J, Aguilera G. Regulation of Corticotrpoin-Releasing Hormone Transcription by cAMP in a Transformed Hypothalamic Cell Line and AtT20 Cells. 2002 Endocrine Society Abstracts.

70.Kasckow JW, Mulchahey, JJ, Pisarska M, Aguilera G, Chen H, Nikodemova M, Dautzensberg F, Sheriff S. Corticotropin-Releasing Hormone and Protein Kinase A Mediated CRH Receptor Signaling in an Immortalized Hypothalamic Cell Line. 2002 Endocrine Society Abstracts.

71.JW Kasckow, S Mohamed, S Zisook, D Jeste. Pharmacologic Management of Schizophrenia in Late Life: An Update. 2003 American Association Annual Meeting, Honolulu. In the symposium, in the Consortium for Research in Older People with Schizophrenia IV; Co-Chairs- Kasckow JW and Jeste D.

72.Baker D, Geracioti TD, Ekhator NN, Kasckow JW, Dashevsky B, Horn PS, Bednarik L. Increased Basal Serial Cerebrospinal Fluid Cortisol Concentrations in Posttraumatic Stress Disorder. 2003 Society for Biological Psychiatry Abstracts.

73.Nikodemova M, Liu Y, Kasckow JW, Greti Aguilera G. 3’ region of the Corticotropin Releasing Hormone (CRH) Gene Affects Transcriptional And Post-Transcriptional Regulation of Gene Expression. 2003 Endocrine Society Abstracts.

74.Kalintchenko N, Liu Y, Kasckow JW , Aguilera G. Self-Limitation of cAMP-Stimulated CRH Transcription in the hypothalamic Cell Line 4B: Role of inducible cAMP Early Repressor (ICER). 2003 Society for Neuroscience Abstracts.

75.Montross LP, Mohamed S, Kasckow JW. Predicting Suicidality Among Those With Schizophrenia. 37

th Annual Convention of the Association for the Advancement of

Behavior Therapy (AABT) Boston. 2003.

76.Montross LP, Mohamed S, Kasckow JW, Zisook S. Suicidality Among The Elderly With Schizophrenia: The Predictive Value of Specific Demographic, Diagnostic, and Intrapsychic Variables. 11th Annual International Congress of the International Psychogeriatrics Association (IPA). 2003.

77.Coccaro E, Frank E; Kasckow J, Geracioti T. CSF Testosterone: Relationship With Aggression and Risk Taking in Male Personality Disorded Subjects. 2004 Meeting of the International Society for Psychoneuroendocrinology.

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78.Kasckow JW, Mohamed S, Zisook S, Jeste D. Pharmacologic Treatment of Schizophrenia in Late Life: An Update. 2004 American Association Annual Meeting, Baltimore. In the symposium, Consortium for Research in Older People with Schizophrenia V; Chair Kasckow JW.

79.Kasckow JW, Segar T, Herman JP. Neuroendocrine responses to restraint stress. and dexamethasone challenge in aged Fisher 344/Brown Norway hybrid rats. 2004 Endocrine Society Meeting, New Orleans, LA.

80.Kasckow JW, Segar T, Herman JP. Neuroendocrine and Behavioral Responses to Restraint Stress. and Dexamethasone Challenge in Aged Fisher 344/Brown Norway hybrid rats. 2004 Society for Neuroscience Meeting, San Diego, CA.

81.Xiao C, Sartin JL, Mulchahey JJ, Zemlan FP, Sheriff S, Segar TM, Herman JP, Kasckow JW. Aging Associated Changes in Amygdalar CRH and CRH-BP in Fisher 344 Rats. 2004 Society for Neuroscience Meeting, San Diego, CA.

82.Xiao C, Mueller N, Kasckow J, Herman JP. Glucocorticoid Receptor Expression in CA1 Hippocampal Astrocytes of Aged Fisher 344 (F344) and F344/Brown Norway Rats. 2005 Society for Neuroscience Meeting, Washington D.C.

83.Segar T, Kasckow JW, Welge J, Brusetle A, Herman JP. Greater Aging Associated Variability to Corticosterone Responses to Restraint Stress in Fisher 344(F344) vs. F344/Brown Norway Rats. 2005 Society for Neuroscience Meeting, Washington D.C.

84.Bruestle AB, Packard B, Segar T, Kasckow J, Muglia L, Herman J. Hippocampal/Cortical Glucocorticoid Receptor Knock Out Increases HPA Axis Responsiveness to Chronic Stress. 2005 Society for Neuroscience Meeting, Washington D.C.

85.Ciesla J, Kasckow JW, Mohamed S. Insight, Positive Symptoms, Negative Symptoms, and Depression Among Older Patients with Schizophrenia. 2005 Annual AAGP Meeting, San Diego, CA

86.Mohamed S, Klein CV, Aslam M, Ciesla J, Kasckow JW. Safety and Efficacy of Escitalopram in the Treatment of Co-morbid Anxiety and Depression in the Elderly. 2005 Annual AAGP Meeting, San Diego, CA.

87.Kasckow JW, Mohamed S, Patterson T, Golshan S, Kubiak G, Jeste D, Sizook S. Functional Measures in Middle Aged and Older Adults with Schizophrenia and Depressive Symptoms. 2005 Annual AAGP Meeting, San Diego, CA.

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88.Montross L, Kasckow JW, Golshan S, Solorzano E, Lehman, D, Sizook S. The Importance of Screening for Suicidality in Middle aged and Older Persons with Schizophrenia. 2006 Annual AAGP Meeting, San Juan, Puerto Rico.

89.Kasckow JW, Montross L, Golshan S, Mohamed S, Patterson T, Jeste D, Sizook S. Relationship of Suicidality in Middle Aged and Older Patients with Schizophrenia to Diagnostic Status, Functioning and Quality of Life. 2006 Annual AAGP Meeting, San Juan, Puerto Rico.

90.Sakihara S, Kageyama K, Kasckow J, Suda T. Leptin Can Suppress the Transcription of Corticotropin-Releasing Factor in the Immortalized Hypothalamic Neuron. 2006 Endocrine Society Meeting, Boston, MA.

91.Xiao C, Kasckow JW, Bruestle A, Herman JP. Aging Related Changes in GABergic Terminals in the Paraventricular Nucleus in Fisher 344 (F344) and F344/ Brown Norway (F344/BN). 2006 Society for Neuroscience Meeting, Atlanta, GA.

92.Kasckow J, Golshan S, Mohamed S, Patterson T, Sollorzano E, Fellows I, Zisook S. Quality of Life and Functioning in Middle Aged and Older Adults with Schizophrenia and Depressive Symptoms - the Symposium: Depressive Symptoms in Older Patients with Schizophrenia. J Kasckow, Chair 2007 AAGP Annual Meeting, New Orleans, LA.

93.Mohamed S, Golshan S, Kasckow JW, Patterson T, Sollanzano E, Fellows I, Zisook S. Cognitive Functioning in Middle Aged and Older Adults with Schizophrenia and Depressive Symptoms. 2007 AAGP Annual Meeting, New Orleans, LA.

94.Kasckow J. Treating Depression in Older Patients with Schizophrenia, in the Workshop Addressing the Needs of Community Dwelling Persons with Schizophrenia 2007 American Psychiatric Association Annual Meeting. San Diego, CA.

95.Lacro J; Mittal D, Fellows I, Golshan S, Patterson T, Kasckow J, Zisook S. Ability. to Manage Medication Regimen Affected by Depressive Symptoms and Medical Burden. 2007 Annual meeting of the College of Psychiatric and Neurologic Pharmacists. Colorado Springs, Colorado.

96.Osatuke K, Reid M, Allen N, William B. Kasckow J, Zisook S. Styles Linking Insight to Assimilation of Subjectively Problematic Experiences in Schizophrenia.2007 Society for Psychotherapy Research Meeting, Madison, Wi.

97.Cohen CI, Kasckow JW, Diwan SP, Bankole A, Reyes PN, Palekar NJ, Sapra M. Treatment of Depression in Patients with Schizophrenia, in the Workshop: Addressing the Needs of Community Dwelling Persons with Schizophrenia, chair: J

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Kasckow. 2007 Annual American Psychiatric Association Institute on Psychiatric Services Meeting, New Orleans, LA.

98.Kasckow J, Xiao C, Herman JP. Age-related enhancement of glutamatergic innervation of the paraventricular nucleus in F344 and F344/BN F1 hybrid rats. 2007 Society for Neuroscience Meeting, San Diego, CA.

99. Moriyama T, Kageyama K, Hanada K, Iwasaki Y, Sakihara S, Nigawara T, Kasckow J, Suda T. Hypothalamic cAMP agonists stimulate corticotropin-releasing factor, vasopressin, and interleukin-6 gene promoters in hypothalamic 4B cells. 2007 Endocrine Society. Toronto, Canada.

100. Kasckow J, Fellows I, Golshan S, Solorzano E, Zisook S. Citalopram Augmentation in Schizophrenia and Depressive Symptoms: Effects of Age on Response Rate. 2008 AAGP Annual Meeting, Orlando, FL.

101.Nyer M, Kasckow J, Fellows I, Lawrence E, Golshan S, Solorzano E, Zisook S. The relationship of marital status and clinical characteristics in middle-aged and older patients with schizophrenia and depressive symptoms. 2008 AAGP Annual Meeting, Orlando, FL.

102. Kasckow J, Patterson T, Fellows I, Golshan S, Solorzano E, Zickmund S, Mohamed S, Zisook S. Effect of Antidepressant Augmentation in Middle Age and Older Adults with Schizophrenia and Depressive Symptoms on Functioning and Service Utilization, in the symposium, Treating Depression in Patients with Schizophrenia, (Zisook S and Kasckow J, co chairs), 2008 American Psychiatric Association Meeting (in press).

103. Zisook S Kasckow J, Mohamed S, Golshan S, Fellows I, , Solorzano E, Lehman D. Antidepressant Augmentation of Subsyndromal Depressive Symptoms in Middle Age and Older Patients with Schizophrenia, in the symposium, Treating Depression in Patients with Schizophrenia, (Zisook S and Kasckow J, co chairs), 2008 American Psychiatric Association Meeting, Washington D.C.

104. Mohamed S, Golshan S, Kasckow J, Patterson T, Solorzano E, Fellows I, Zisook S. Cognitive Functioning in Middle Age and Older Adults with Schizophrenia and Depressive Symptoms, in the symposium, Treating Depression in Patients with Schizophrenia, (Zisook S and Kasckow J, co chairs), 2008 American Psychiatric Association Meeting, Washington D.C.

105. Ogura E, Kageyama K, Kasckow J, Suda T. Estradiol regulates corticotropin-releasing factor gene and interleukin-6 production via estrogen receptor type [beta] in hypothalamic cells. 2008 Endocrine Society. San Francisco, CA (in press).

106. Kasckow J, Fellows I, Golshan S, Solorzano E, Zisook S. Rating Scales for Assessing Depresison in Older Patients with Schizophrenia" in the symposium

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Recent Research Advances in Late Life Schizophrenia (Kasckow J, chair) 2009 Annual American Association for Geriatric Psychiatry.

107. Kasckow J, Morse J. Teaching Problem Solving Therapy-Primary Care to Geropsychiatry Residents Depressed Patients in a VA Primary Care in a VA based Home Setting in the symposium Teaching Psychotherapy to Geriatric Psychiatry Fellows (Miller M, chair) 2009 Annual American Association for Geriatric Psychiatry.

108. Zisook S, Kasckow J, Fellows I, Golshan S,. Effects of Citalopram on Suicidal Ideation in Middle-Aged and Older Outpatients with Schizophrenia with Subyndromal Depression, in the symposium Recent Research Advances in Late Life Schizophrenia (Kasckow J, chair) 2009 Annual American Association for Geriatric Psychiatry Meeting.

109. Kasckow J, Gurklis J, Thompson R, Crofutt R, Murray T, Richmond I, Haas G. Telehealth Monitoring of Patients with Schizophrenia and Suicidal Behavior 2009 International Congress of Schizophrenia Annual Meeting.

110. Kasckow J, Brown C, Morse J, Karpov I, Bensasi S, Thomas S, Ford A, Reynolds C. Racial Preferences for Participation in a Depression Prevention Research Intervention. 2009 Annual American Association for Geriatric Psychiatry.

111. MacShane S, Kasckow J, Taylor M, Bender E, Kirkland J, Crofutt R, Murray T, Richmond I, Gurklis J, Haas G. Implementation of a Telehealth Intervention for Patients with Schizophrenia and Suicidality. 6

th Annual Florida Magnet Nursing Research

Conference: Research at the Point of Care. 2009

112. Kasckow J, Ingram E, Tew J, Brown C, Morse J, Connor K , Reynolds C, Oslin D. Racial Preferences in African American Veterans with Subsyndromal Depression. 2009 APA Institute for Health Services Meeting, New York.

113. Kasckow J, Liu N, Haas G, Phillips M. Case-control study of the relationship of depressive symptoms to suicide in a community-based sample of individuals with schizophrenia in China 2009 American Psychiatric Association Meeting. San Francisco, CA .

114. Kasckow JW, Lanouette N, Patterson T, Fellows I, Golshan S, Solorzano E, Zisook S. Treatment of Subsyndromal Depressive Symptoms in Middle-Age and Older Adults with Schizophrenia: Effect on Functioning. 3

rd Annual VA Mental

Health Conference Washington DC 2009.

115. MacShane S, Kasckow J, Taylor M, Bender E, Kirkland J, Crofutt R, Murray T, Richmond I, Gurklis J, Haas G. Implementation of a Telehealth Intervention for Patients with Schizophrenia and Suicidality. VAPHS Research Week. 2009

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116. Kasckow J, Liu N, Haas G, Phillips M. Case-control study of the relationship of depressive symptoms to suicide in a community-based sample of individuals with schizophrenia in China. 2009 APA Institute for Psychiatric Services Meeting, New York.

117. Kasckow J. Subsyndromal Depression in Late Life. International Congress of Psychoneuropharmacology Annual Meeting. Baltimore. 2009

118. Kasckow J, Haas G. Telehealth Monitoring of Older Patients with Schizophrenia at Risk for Suicide, in the symposium, Suicidal Behavior in the Older Patient with Schizophrenia (Kasckow J, chair) 2010 Annual American Association for Geriatric Psychiatry.

119. Kasckow J, Ingram E, Tew J, Brown C, Morse J, Connor K , Reynolds C, Oslin D. Treatment Attitudes of Subsyndromally Depressed African American and Caucasian Primary Care Veterans. Implementing a Public Health Model for Meeting the Mental Health Needs of Veterans. Baltimore. 2010.

120. Kasckow J, Gurklis J, Felmet K, Thompson R, Crofutt R, Murray T, Richmond I, Haas G Use of Telehealth Intervention for Patients with Schizophrenia and Suicidality: Preliminary Outcome Data. Implementing a Public Health Model for Meeting the Mental Health Needs of Veterans. Baltimore. 2010.

121. Kasckow J, Brown C, Morse J, Begley A, Bensasi S, Reynolds C. Rates of traumatic exposure and post traumatic stress disorder in subsyndromally depressed participants in a depression prevention research intervention International Congress of Geriatric Psychoneuropharmacology. Athens, Greece, 2010.

122. Kasckow J., Appelt C, Daley D., Felmet K, Haas G. Development of a Coping Manual for Individuals with Schizophrenia and Suicidal Behaviors. 2010 APA Institute for Health Services Meeting, Boston.

123. Kasckow J, Gurklis J, Felmet K, Thompson R, Haas G. Implementation of a Telehealth Intervention for Patients with Schizophrenia and Suicidality. 2010 APA Institute for Health Services Meeting, Boston.

124. Kasckow J, Daley D, Appelt C, Felmet K, Haas G. Development of a Coping Manual for Middle Aged and Older Patients with Schizophrenia and Suicidal Behaviors, in the symposium, Late Life Schizophrenia: Recent Advances (Kasckow J, chair), 2011 Annual American Association for Geriatric Psychiatry.

125. Vahia I, Kasckow J, Golshan S, Zisook S. Naturalistic follow-up of older adults with schizophrenia and schizoaffective disorder with subsyndromal depression, in the symposium, Late Life Schizophrenia: Recent Advances (Kasckow J, chair), 2011 Annual American Association for Geriatric Psychiatry, San Antonio, TX.

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126. Kasckow J, Gurklis J, Haas G. A telehealth intervention for suicidal people with schizophrenia. In the symposium, Information Technology Approaches for Improving Outcomes in Patients with Schizophrenia (Kasckow J, chair), 2011 Annual American Psychiatric Association Meeting, Honolulu, HI.

127. Kasckow J, Yaeger D, Magruder K. Symptoms and Levels of Functioning Associated with 4 Different Diagnoses of Subthreshold Post-Traumatic Stress Disorder. 2011 Annual American Psychiatric Association Meeting, Honolulu, HI.

128. Kasckow J, Liu N, Phillips M. Case-Control Study of the Relationship of Functioning to Suicide in a Community-Based Sample of Individuals with Schizophrenia in China. 2011 Annual American Psychiatric Association Meeting, Honolulu, HI .

129. Kasckow J, Brown C, Morse J, Begley A, Bensasi S, Reynolds C. Comorbidity in Subsyndromally Depressed Participants Presenting for a Depression Prevention Research Intervention. 2011 Annual American Association for Geriatric Psychiatry San Antonio, TX.

130. Kasckow J., Haas G, Appelt C, Daley D., Felmet K, Haas G. Development of a Coping Manual for Individuals with Schizophrenia and Suicidal Behaviors. 2011 DoD/VA Suicide Prevention Conference, Boston, MA.

131. Kasckow J, Haas G, Gurklis J. A Telehealth Intervention for Suicidal Veterans with Schizophrenia. 2011 DoD/VA Suicide Prevention Conference Boston, MA.

132. Kasckow J, Haas G, Gurklis J. A Telehealth Intervention for Suicidal Patients with Schizophrenia, in the poster symposium: The Use of Information Technology to Provide Care for People with Schizophrenia (Kasckow J, chair), 2011 International Congress of Schizophrenia Research, Colorado Springs, CO.

133. Kasckow J, Appelt C, Felmet K, Daley D, Haas G. Development a Coping Manual for Veterans with Schizophrenia and Suicidal Behaviors: Qualitative Findings. 2011 meeting: Improving Veterans Mental Health Care for the 21

st

Century. Baltimore, MD.

134. Kasckow J, Begley A, Bensasi S, Reynolds C. Prevention of Post Traumatic Stress Disorder in Older Individuals with Subsyndromal Depression. In the meeting: Netherlands Institute of Mental Health and Addiction: Shaping the Research Agenda for Depression Intervention. Utrecht, Holland, 2011.

135. Kasckow J, Begley A, Reynolds C. Post Traumatic Stress Disorder Symptoms in Emotionally Distressed Patients Referred for a Depression Prevention Intervention in the symposium: Post Traumatic Stress Disorder in Older Individuals: Research

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Advances (Kasckow J chair, Magruder K, co-chair), International Congress of Geriatric Psychoneuropharmacology , Irvine, CA. 2011.

136. Kasckow J, Luther J, Haas GL. Depression as a Predictor of Suicidal Behavior in Patients with Schizophrenia: Does Age Matter? in the symposium - New Research Advances in Late Life Schizophrenia. (Kasckow J, chair), 2012 Annual American Association for Geriatric Psychiatry, Washington DC (in press).

137. Kasckow J, Golshan S, Zisook S. Subsyndromal Depressive Symptoms in Middle Aged and Older Patients with Schizophrenia: Relationship to Suicidal Ideation. 2012 Annual American Association for Geriatric Psychiatry. Washington DC.

138. Kasckow J, Yaeger D, Magruder K. Levels of Symptom Severity and Functioning in 4 Different Dedfinitions of Subthreshold Post-Traumatic Stress Disorder in Primary Veterans. 2012 Annual American Psychiatric Association Meeting, Philadelphia, PA.

140. Kasckow J, Karp J, Whyte E, Brown C, Morse J, Begley A, Bensasi S, Reynolds C. The Impact of Comorbid Anxiety Disorders in Subsyndromally Depressed Participants Presenting for a Depression Prevention Research Intervention. 2012 Annual American Psychiatric Association Meeting, Philadelphia, PA.

141. Kasckow J, Mrkva, A Rotondi, M Chinman, L Fox, M Loganathan, G Haas, S Zickmund; Optimizing Scripted Dialogues for an E-Health Intervention for Suicidal Veterans with Schizophrenia: A ‘User Design’ Approach using Qualitative Methods. 2012 DoD/VA Suicide Prevention Conference Washington DC.

142. Cornelius J, Kasckow J, Haas G. Disproportionate Suicidality in Veterans with Comorbid Major Depression and an Alcohol Use Disorder. 2012 DoD/VA Suicide Prevention Conference Washington DC.

143. Kasckow J, Yaeger D, Magruder K. Symptoms and Levels of Functioning Associated with 4 Different Diagnoses of Subthreshold Post-Traumatic Stress Disorder. 2012 APA Insitute for Psychiatric Services Meeting. NY, NY.

144. Kasckow J, Karp J, Whyte E, Brown C, Morse J, Begley A, Bensasi S, Reynolds C. The Impact of Comorbid Anxiety Disorders in Subsyndromally Depressed Participants Presenting for a Depression Prevention Research Intervention. 2012 APA Institute for Psychiatric Services Meeting. NY, NY.

145. Kasckow J, Begley A, Morse J, Bensasi S, Reynolds C. Prevention and Treatment of Post Traumatic Stress Disorder (PTSD) Symptoms in Older Individuals with Subsyndromal Depression, in the symposium: Psychosocial Interventions for Older

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Patients with Post Traumatic Stress Disorder. 2013 Annual Meeting of the American Association for Geriatric Psychiatry, Los Angeles, CA.

146. Kasckow J, Luther J, Fox L, Loganathan M, Haas G. Telehealth Monitoring of Older Patients with Schizophrenia at Risk for Suicide, in the symposium: Advances in Late Life Schizophrenia Research. 2013 Annual Meeting of the American Association for Geriatric Psychiatry, Los Angeles, CA.

147. Kasckow J, Haas GL, Cornelius J, Luther J. Telehealth Monitoring of Suicidal Ideation in Patients Schizophrenia. 2013 International Congress of Schizophrenia Research (in press).

PROFESSIONAL ACTIVITIES

TEACHING:

1996-2006

Director, ACGME Acredited Geropsychiatry Residency University of Cincinnati College of Medicine

Direct supervision for 2 PGY 5 residents per year since 1997 (5 hours supervision per resident/week)

1995-1998 University of Cincinnati College of Medicine:

Preceptor, “Patient Interviewing” Departments of Psychiatry and Family Medicine

Students: Groups of 6-8 1st year medical students for 8 weeks (3 hours contact)

1995-2002

Lecturer for 3rd and 4th year resident didactics (6 per class) which each year was 2 of the following lectures(each 1 hour): 1. Psychopharmacology of Aging 2. Practicing Psychiatry in the Nursing Home 3. Psychopharmacology of Dementia

1995-2006

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Attending Supervisor for 3rd year medical student 3 week rotations (5 hours supervision/week).

2001-2006

PGY2 general Psychiatry residents on VA geropsychiatry ward 7 south for 4 week rotations (6-8 patients; 5 hours supervision per week).

1997-1999, Attending and Preceptor, Ft Thomas Nursing Home for PGY5 geropsychiatry residents (1 hour supervision per week)

2006 Preceptor, Ft Thomas Nursing Home for PGY2 general psychiatry residents (1 hour supervision per week)

1995- 2002

Director: Geropsychiatry journal clubs for PGY5 residents (2X a month)

1995- 2002

Director of Monthly Geropsychiatry Seminars

2002-2006 Ph.D. Thesis Committee Member for Neuroscience Ph.D. for 1-4 students per year)

1996-present Mentor for Postdoctoral Fellows (MD’s, PhD’s, MD, PhD’s; 1-3 per year); currently mentor for Cathleen Appelt, now MIRECC research associate who will start as fellow in Psychiatric Epidemiology

2002-2006 Mentor for Psychology Interns (1-2 per year)

1995-2006

Mentor for Junior Faculty (1-3 per year), including mentor for NARSAD Young Investigator Award, NIH Bstart

2001-2006

Faculty Mentor for T32 Training Program in Neuroendocrinology of Homeostasis (2001-2006)

Yearly lectures to predoctoral and postdoctoral trainees which included talks on either “In vitro Methods in Neuroendocrinology” or “Clinical Research in Stress Neuroendocrinology”

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2003-2007

Co-Investigator/Consultant of University of Cincinnati Reynolds Foundation Grant: “Strengthening Geriatric Education and Care of Elderly Patients in the Greater Cincinnati Tri-State Area.” (Greg Warshaw, M.D., PI), This included :

1.) mentoring junior psychiatry clinician-teachers in the Department of Psychiatry in the care of geriatric patients and to guide them in expanding our geriatric teaching curriculum within the general psychiatry residency program and, 2.) mentor medical students interested in pursuing a career in geriatrics.

2007- present

VA liaison for Geropsychiatry Training program, VA Pittsburgh Health System/Western Psychiatric Institute, University of Pittsburgh

Mentor for University of Pittsburgh geropsychiatry residents (1 resident at a time) for 10 week VA rotations in: Late Life Schizophrenia Clinic (Highland Dr VA), Primary care consultation clinic (Heinz VA), Home Based Primary Care, Palliative Care Rotation (Heinz VA) and Home Based Primary Care Psychotherapy; total of 5 hrs/week.

2008-present

Lecturer for CEU programs for nurse clinicians at VA Pittsburgh Health Care System

1/23/08 – Diagnosis of Schizophrenia

2/20/08 Pharmacologic Treatment of Schizophrenia

3/19/08 Suicidality and Schizophrenia

5/21/08 Diagnosis of Dementia

9/17/08 Mental Status Exam

10/15/08 Mental Status Exam, Cognitive Portion

11/19/08 Diagnosing Depression

12/17/08 Diagnosing Psychosis

1/29/09 Patient Interviewing: Introduction

3/24/09 Patient Interviewing: Obtaining a History

4/28/09 Patient Interviewing: Obtaining a Developmental and Social History

6/23/09 Research in Psychiatry

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7/30/09 Review of Psychopharmacologic Treatment of Schizophrenia

10/1/09 Antidepressant Medications

10/28/09 Mood Stabilizer Medications

12/20/09 Anti-Anxiety Medications

1/28/10 Electro-Convulsive Therapy

3/17/10 Medications for the Chronically Psychotic Patient

5/20/10 Decision Making and Competency in Patients

6/17/10 Diagnosing Depressive and Anxiety Disorders

7/15/10 Overview of Axis II Disorders

9/2/10 Overview of Axis II Disorders – Part 2

10/21/10 Overview of Axis II Disorders- Part 3

11/18/10 Overview of Axis II Disorders- Part 4

1/20/11 Mental Retardation

2/24/11 Antidepressant Uses

3/31/11 Head Trauma: Assessment

4/21/11 Pharmacologic Treatment of Schizophrenia

6/30/11 Suicidality and Schizophrenia

7/21/11 Cognitive Disorders

8/18/11 Use of Mood Stabilizers

9/29/11 Mental Status Testing

11/22/11 Review of Personality Disorders

12/13/11: Review of Personality Disorders- Part II

1/18/12 Personality Disorders- Cluster C 3/7/12 Case Studies- Personality Disorders

4/4/2012 Case Studies: Personality Disorders

5/31/2012 Treatment of Personality Disorders

7/3/2012 Adult Attention Deficit Disorder

8/28/2012 Managing Suicidality

10/23/2012 Telehealth Approach for Treating Patients with Schizophrenia

11/27/2012 Somatic Disorders

2/26/13 Depressive & Anxiety Disorders

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3/27/13 Diagnosis of Dementia

2007-present Faculty Participant – Western Psychiatric Institute and Clinics, Geropsychiatry fellowship journal clubs

2007-present Faculty Member Addiction Fellowship, Western Psychiatric Institute and Clinics/ VA Pittsburgh Health Care System

2009 – present – Preceptor for UPMC Medical Student Rotation at Canterbury Hospital: Dementia

2010 Group Facilitator for the 1st year Introduction to Psychiatry Course 5/11/10: Depression and 5/14/10, 5/13/11: Suicide, UPMC Medical School

Group Facilitator for Medical Student course “Introduction to Medical Decision Making”, each year since Fall 2010

Current Grant Support:

VA Cooperative Studies Program 576 VA Augmentation and Switching Treatments for Improving Depression Outcomes (PI: John Kasckow, MD, PhD.), 10/2012-9/2015; total costs = $350,000

VA HSRD PPO 10-249-2 Improving Outcomes for Suicidal Veterans with Schizophrenia. (PI: John Kasckow, MD, PhD.), 12/2011-11/2012; total costs = $99,998.

VA Pittsburgh CHERP Pilot Program Developing a Telehealth Health Buddy System for Suicidal Veterans with Major Depression. (PI: John Kasckow, MD, PhD). 10/12-9/2013; total costs = $32,000.

VA Cooperative Studies Program 556 The Effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) in Depressed VA Patients (PI: Stephen Forman, MD, PhD.), 8/2011-2/2015; total costs = $ 541140.

NIH 1P01MR010949-01 Adherence and Health related Quality of Life: Translation of Intervention, Co-Investigator (PI; Jacqueline Dunbar-Jacob, Ph.D.), 9/2008-7/2013, total costs = $3,491,570

VA Merit Review. Phospholipids-Arachidonate-Eicosanoids Signalling in Schizophrenia. (PI, J Yao, PhD), 1/2010- 12/2013; total costs = $199,400

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Prior Grant Support:

American Foundation for Suicide Prevention, Development of a Manual for Patients with Schizophrenia and Suicidality, Principal Investigator, 2009-2010, total costs = $20,000

VA MHEC VISN 4 CPP Implementation of Patient Centered Medical Home Model: Targeting the Specific Needs of OEF/OIF Veterans with PTSD within Primary Care. (PI, E Sonel, MD) 7/2010-6/2012 total costs = $207,480.

VA VISN 4 CPPF Feasibility of conducting a study of acupuncture for adjunctive treatment of post-stroke depression (PI, Ed Lee, MD). Total costs = $47,677, 10/2010-9/2012

SBIR phase 2 2R44MH067430-03A1, Development of a Selective Muscarinic Agonist in the Treatment of Schizophrenia, Consultant, (PI, E McGuire, PhD) 2007-2010, total costs = $1,350,000

VA VISN 4 CPPF, Use of Telehealth System to Monitor Suicidality in Schizophrenia, Principal Investigator, 2006-2010, total costs = $50,000

Astra Zeneca, Investigator Initiated, An Open Label Pilot Study of the Efficacy and Safety of Seroquel XR in the Treatment of Geriatric Patients with Schizophrenia, Principal Investigator, 11/2008- 10/2010; total costs = $25,000

NIMH R01 MH6398, Antidepressant Augmentation of Late Life Schizophrenia, Principal Investigator, 2001- 2007, total costs = $1,665,000

NIMH 1 R01 MH069725-01A2. Anatomical Plasticity and HPA Axis Dysfunction, Co-Investigator, (PI: James Herman, Ph.D.) 2005-2006, total costs = $1,566,000

Donald W. Reynolds Foundation, Strengthening Geriatric Education and Care of Elderly Patients in the Greater Cincinnati Tri-Sate Area.Co-Investigator/Consultant, (PI; Greg Warshaw, M.D.), 2003-2007, total costs = $2,600,000

SBIR phase 2, 1R43 AG20454-01A1, SBIR phase 2, 1R43 AG20454-01A1, Utility of Muscarinic Agonists for Alzheimer's Disease Consultant, (PI; E McGuire, Ph.D.), 2004-2006, total costs = $749,740

NIMH1 R21 AT00567-01 Phytoestrogens and Cognition in Menopause Co-Investigator (PI: R Krokorian, Ph.D.) 2002-2006, total costs = $375,000

VA Merit Review, Cerebrospinal Fluid AntiPlasma Pro- inflammatory Cylokines: Relationship to Combat Exposure, PTSD and HealthStatus. Co-Investigator, (PI: D. Baker, M.D.) 2003-2007, total costs = $577,000

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Office of Naval Research Novel Genes Involved in the Molecular Response in Pigs to the Effects of Heat-Stress Co-Investigator (PI, J Sartin, Ph.D.) 2003-2006, total costs = $332,843

NIMH-UCSD Geriatric Interventional Research Center Grant, Late Life Psychosis, Principal Investigator, 1999-2000, total costs = $5,000

VA Merit Review 2, Regulation of Amygdalar CRF in Late Life Depression, Principal Investigator, 1998-2001, total costs = $149,900

NIMH K01 MH001545-01, Stress Neuropeptides, Depression and Aging, Principal Investigator, 1998-2003, total costs = $749,338

R03 MH60819-3E1, Neurocircuits, HPA Dysfunction and Affective Disorders, (PI: Jim Herman, Ph.D.) Co-Investigator, 1999-2003, total costs = $100,000,

NIH/NIDDK 1T32 DK59803-01, Training Program in Neuroendocrinology of Homeostasis Co-Investigator, (PI: Steve Woods, Ph.D.) 2001 - 2006, total costs = $148,752,

VA Merit Review, Serial CSF Studies in Combat Veterans with PTSD Co-Investigator, (PI: Thomas Geracioti, M.D.) 1997-2000, total costs = $425,000

VA Merit Review, Central Nervous System Cytokines and CRH in Gulf War Veterans with Unexplained Symptoms, Co-Investigator, (PI: Dewleen Baker, M.D.) 1998-2001 total costs = $299,100

NARSAD Young Investigator’s Award, Cellular Regulation of Corticotropin-Releasing Factor Principal Investigator 1995-1997, total costs = $60,000

Pfizer Fellow in Biological Psychiatry/Neuroscience, Regulation of Corticotropin Releasing Factor, Principal Investigator 1993-96, total costs = $60,000

VA Fellowship in Psychiatry, Corticotropin Releasing Factor Regulation Principal Investigator, 1993-1994

NIMH Fellowship in Psychiatry and Biobehavioral Sciences, Principal Investigator, 1990-1993

NIH Medical Scientist Training Program Grant: Principal Investigator, 1980-87

Seminars and Invited Lectureships Related to Research

1/22/97 “Cytokine Regulation of CRH in the Brain”, Department of Medical Microbiology and Immunology, Ohio State University

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4/25/97 and 4/26/97 Moderator for Symposium – “As the Brain Ages: Practical Points in Geriatric Assessment” as well as Lecturer on “Depression in the Elderly” in same symposia, Dayton and Cincinnati, OH

8/21/97 “Role of the Immune System in the Pathogenesis of Depression in Patients with Alzheimer’s Disease” in International Psychogeriatric Association Annual Meeting, Jerusalem, Israel

9/10/97 “Treatment of Agitation in the Demented Elderly Patient”, Mary Free Bed Hospital and Rehabilitation Center, Grand Rapids, MI

9/16/97 “Behavioral Agitation in Dementia” Grand Rounds for the Macomb County Medical Society, Detroit, Michigan

10/8/97 “Late Life Depression” Internal Medicine Grand Rounds, Dayton VA Medical Center

10/23/97 “Late Life Dementia” in a symposium entitled “Aging in the Twenty First Century” Dayton VA Medical Center

11/15/97 “Depression” in a symposium entitled “The New Cognitive Neuropsychiatry: The Role of Serotonin and Norepinephrine in Depression, Personality Disorders, Attention Deficit Disorder, Anxiety and Pain, Case Western Reserve Medical Center

11/23/97 “Late Life Depression” at Symposium “Contemporary Issues in Psychiatry Cincinnati, OH

4/17/98 “Agitation and Aggression in the Elderly” Department of Psychiatry Grand Rounds, Marshall University, Huntington, W VA

4/23/98 “The Role of Corticotropin-Releasing Factor (CRF) in Depressive Disorders” Department of Psychiatry Seminar, University of Pittsburgh, Pittsburgh, PA

5/15/98 “Atypical Anti-Psychotics” Department of Psychiatry Grand Rounds, Eastern Tennessee State University, Bristol, TN

5/15/98 “Psychoimmunology of Stress” Department of Psychiatry Seminar, Eastern Tennessee State University. Bristol, TN

7/2/98 “Alzheimer’s Dementia: Developments over the Past 15 Years and Current Research” Medical Grand Rounds, The Christ Hospital, Cincinnati, OH

7/21/98 “New Approaches to Behavioral Management in Demented Patients”

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Twelfth Annual Summer Series on Geriatric Medicine, Jewish Hospital, Cincinnati, OH

9/8/98 “Agitation and Aggression in Bipolar Patients” Sinai Hospital, Psychiatry Grand Rounds, Baltimore, MD

9/26/98 “Treatment of Manic-Like Symptoms in the Elderly” University of Louisville Fourth Annual Bipolar Symposium, Louisville, KY

9/30/98 “Dementia and Depression” Dayton VA Psychiatry Grand Rounds, Dayton, OH

10/12/98 “Diagnostic and Treatment Issues Involved with Behavioral Disturbances Associated with Dementia” Northern KY Long Term Care Medical Directors and Nurses, Covington, KY

10/14/98 “Bipolar Disorder in the Geriatric Population” Psychiatry Grand Rounds, Chestnut Ridge Hospital, Morgantown, W VA

10/19/98 “Panic Disorder in the Elderly” AAGP Regional Symposium on Late Life Depression and Co-morbid Illness, Cleveland, OH

10/21/98 “Alzheimer’s Disease” Dayton VA Medical Ground Rounds, Dayton, OH

10/28/98 “Treatment of Agitation and Aggression in the Elderly” St. Margaret Mercy Healthcare Centers – Medical Staff Seminar, Merriville, IN 10/29/98 “Behavior Management in the Long Term Care Elderly” American Society of Consultant Pharmacists, Illinois Chapter, Chicago, Ill

11/12/98 “Antipsychotic Update” Ohio State Television Omen Program, Columbus, OH

1/26/99 “Update on Antidepressants” Tennessee Psychiatric Association, Knoxville, TN

2/3/99 “Depression in Late Life” Dayton VAMC, Dayton, OH

3/4/99 “Atypical Antipsychotic Use” Boston University/Bedford VAMC, Bosoton, MA

3/13/99 Treatment of the Behavioral Sequelae of Dementia Update on the Neuropsychiatry of Aging, Henry Ford Behavioral Sciences, Div of Geriatric Psychiatry, Dearborn, MI

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5/13/99 “Treatment of Geriatric Depression” Dept of Medicine Florida Hospital, Orlando, Fl

5/18/99 “Treatment of Depression in the Elderly” Grand Rounds, University of Illinois, Chicago, Il

7/10/99 “Treatment of the Behaviorally Agitated Elderly Demented Patient ‘ CME Case Conference, Cleveland, OH

9/15/99 “Dementia and Depression” American Academy of Family Physicians Annual Meeting part of Symposium Treatment of Depression in the New Millenium, Chair- John Kasckow, Orlando, FL,

9/23/99 “Regulation of Amygdalar Corticotropin Releasing Factor and its Binding Protein”, University of Reading School of Animal and Microbial Sciences, Division of Cell and Molecular Biology, Reading, England

11/5/99 “Treatment of Behavioral Agitation in the Elderly” Washington Hospital Symposium on Aging, Washington, PA

1/18/00 “Regulation of Corticotropin Releasing Factor in vitro National Institute of Child and Human Development, NIH”, Bethesda, MD

1/27/00 “Regulation of Corticotropin Releasing Factor in vitro Wright State Dept of Pharmacology”, Dayton, OH

2/4/00 “Regulation of Corticotropin Releasing Factor in vitro HPA Axis Cross Disciplinary Networks Conference”, New Orleans, LA

2/5/00 “Viral Mechanisms of Cell Immortalization HPA Axis Cross Disciplinary Networks Conference”, New Orleans, LA

3/6/01 “Corticotropin Releasing Factor Regulation” St Louis University Dept of Psychiatry Grand Rounds, St Louis, Mo

4/26/01 “Corticotropin Releasing Factor Regulation and Late Life Depression” Duke University Dept of Psychiatry Grand Rounds, Durham, NC

10/29/01 “University of Chicago Grand Rounds: Diagnosis and Treatment of Schizophrenia in the Elderly”, Chicago, Il

4/2/02 “Diagnosis and Treatment of Dementia” Good Samaritan Hospital Grand Rounds, Dayton, OH

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3/22/02 “University of Tennessee Grand Rounds Dept Psychiatry” Late Life Schizophrenia

3/20/02 “Cincinnati Psychiatry Society” Geriatric Depression

5/3/02 Responses to Medications in Elderly Schizophrenic Patients at Dayton VA Conference: “Late Life and Psychiatric Disorders Conference”, Dayton, OH

6/2/02 “Comparing Pharmacologic Antipsychotic Therapies in the Elderly Patient” NADONA CME Satellite Symposium, Nashville, TN

6/27/02 “The effects of aging on the HPA axis: the effects of age on behavioral responses to stress in animals”, CINP 2002 meeting, Montreal, Canada

8/2/02 “Diagnosis and Treatment of Dementia” Dayton VAMC, Dayton, OH

9/13/02 Wright State Grand Rounds: Diagnosis and Treatment of Dementia? Dayton, OH

11/8/02 “Case Western Reserve School of Medicine Grand Rounds” Diagnosis and Treatment of Depression in the Elderly, Cleveland, OH

12/11/02 “Update on the Treatment of Dementia” Dayton VA CME program, Dayton, OH

1/10/03 “Schizophrenia in Late Life” University of Hawaii Grand Rounds, Honolulu, HI

2/12/03 “Diagnosis and Treatment of Late Life Schizophrenia” University of Nebraska Dept of Psychiatry Grand Rounds Omaha, NE

4/23/03 “Diagnosis and Treatment of Dementia” Wright State University Grand Rounds Dept of Psychiatry Dayton, OH

9/20/03 Anxiety Disorders: Neurobiology and Comorbid Depression in the Conference: Important Topics in Managing Anxiety and Depression: CBT and Pharmacology Denver, CO

10/18/03 “Considerations in Prescribing the Newer Psychotropics” 15th Annual Statewide Geriatric Medicine Conference Cambridge, OH

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10/30/03 “Geriatric Depression” Tennessee Academy of Family Physicians, 55

th Annual Assembly

Gatlinberg, TN

11/22/03 “Current Research on Mechanisms and Receptor Selectivity in Major Depressive Disorder” Cleveland, OH

12/3/03 “Schizophrenia: An Overview of Diagnosis and Treatment” Danville VAMC, Danville, Il

12/16/03 “Wright State Grand Rounds: Schizophrenia in Late Life” Dayton, OH

12/17/03 “Schizophrenia: An Overview of Diagnosis and Treatment” Brecksville, VAMC, Brecksville, OH

2/21/04 “Psychopharmacology of Bipolar Disorder” Creative Educational Concepts Foundation Lectures for Health Care Providers Ananheim, CA

2/21/04 “Bipolarity in Late Life” Creative Educational Concepts Foundation Lectures for Health Care Providers Ananheim, CA

3/13/04 “Bipolar Disorder in Later Life” Creative Educational Concepts Foundation Lectures for Health Care Providers San Francisco, CA

4/2/04 “Duke University Medical Center 1st Annual Psychopharmacology Update” Pharmacotherapy of Dementia”, Ft Myers, FL

4/29/04 “Controlling Acute Agitation in an Emergency Setting” Greenwood Leflore Hospital, Greenwood, MI

6/2/04 “Atypical Antipsychotics in the Elderly” Creative Educational Concepts Foundation Meeting for Health Care Providers Greensboro, NC

6/5/04 “Atypical Antipsychotics in the Treatment of Dementia” France Foundation Psychiatry Updates, Los Angeles, CA

10/14/04 “Overview of Current Drug Development in Geriatric Psychiatry: An Update In the Symposium”, Workshop: Conduct of Clinical Trials in Geriatric Psychiatry, John Kasckow, Chair 4

th Annual Meeting, International College of Geriatric

Psychoneuropharmacology, Basel, Switzerland

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12/6/04 “Pharmacologic Treatment of Schizophrenia” Louisville Psychiatrists, Louisville, KY

1/25/05 “Treatment of Depression and Anxiety” Allen Gynecologic Practice, Cincinnati, OH

2/16/05 “Diagnosis and Treatment of Depression and Anxiety” Madison Physicians, Madison, IN

3/16/05 “Disorders involving Depression and Anxiety” St Louis Psychiatrists, St Louis, MO

3/2/05 “Treatment of Anxiety and Depression” New Orleans Psychiatrists, New Orleans, LA

3/22/05 “Treatment of Anxiety and Depression” Orlando Physicians, Orlando, FL

5/2/05 “Treatment of Psychosis” Cincinnati Physicians, Cincinnati, OH

9/29/05 “Treatment of Psychosis” Columbia Physicians, Columbia, SC

11/4/05 “Psychosis in Late Life” Washington Hospital Updates in Psychiatry, Washington, PA

11/9/05 “Treatment of Schizophrenia” Western State Hospital, Hopkinsville, IN

1/20/06 “Management of Alzheimers Disease” Poplar Bluffs Medical Clinic, Poplar Bluff, Mo

2/17/06 “Changes in the Treatment of Alzheimers Disease” NEA Clinics, Jonesboro, AR

3/29/06 “Diagnosing and Treating Alzheimers Disease in the Primary Care Setting” Patients First Clinical Physicians, Bellevue, KY

4/13/06 “Diagnosis and Treatment of Comorbid Anxiety and Depressive Disorders” Brown County Counseling Center, Georgetown, OH

4/14/06 “Treatment of Alcohol Dependence in the Elderly” Kniebert Clinic, Poplar Bluffs, MO

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4/15/06 “Atypical Antipsychotics in the Elderly” Creative Educational Concepts Foundation Meeting for Health Care Providers Lexington, KY

5/8/06 “Neuroendocrine Regulation of Stress in Aging” University of Pittsburgh Dept of Psychiatry, Pittsburgh, PA

5/18/06 “Diagnosis and Treatment of Schizophrenia in Late Life” Central Texas Veterans Health Care System, Waco, TX

5/31/06 “Diagnosis and Treatment of Dementia” Jonesboro Neurology and Psychiatry, Jonesboro, AR

6/28/06 “Treatment of Schizophrenia” Carlton Manor Long Term Care, Washington Court House, OH

11/7/06 “Antipsychotic Usage in Schizophrenia: The CATIE Study” Houston Physicians and Pharmacists, Houston, TX

5/3/07 “Importance of Early Diagnosis and Treatment of Schizophrenia” Mayview State Hospital Physicians, Bridgeville, PA

6/14/07 “Use of Telehealth Systems to Monitor Suicidality in Schizophrenia” University of Rochester Summer Research Institute in Suicide Prevention Rochester, NY

6/28/07 “Treatment of Schizophrenia” Bristol Physicians, Bristol, TN

9/13/07 “Suicidality in Older Patients with Schizophrenia” Beijing Suicide Research and Prevention Center, Beijing, China

9/14/07 “Depression in Older Patients with Schizophrenia” Beijing Hui Long Guan Hospital, Beijing, China

10/11/07 “Diagnosis and Teatment of Depression and Anxiety” Midtown Internal Medicine, Memphis, TN

4/15/08 “Evidence Basis for Problem Solving Therapy” VISN 4 Behavioral Health Laboratory course for VA Nurses on Problem Solving Therapy

10/7/08 “Late Life Depression: Diagnosis and Treatment” VA Pittsburgh Primary Care Seminar

1/9/09 “Late Life Psychosis.

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VA Pittsburgh Health Care System Geriatric Research Education and Clinical Center Seminar

1/14/09 “Neuroleptic Malignant Syndrome” Department of Internal Medicine Chief of Medicine Conference, University of Pittsburgh Medical Center/VA Pittsburgh Health Care System

2/10/09 “Diagnosis and Treatment of Psychosis in the Elderly” VA Pittsburgh Primary Care Service

2/20/09 “Research Supporting Use of Problem Solving Therapy for Depression Treatment” Philadelphia VA MIRECC

3/2/09 Late Life Psychotic Disorders University of Pittsburgh Course for Certification in Gerontology

2/1/10 Screening for Dementia UPMC General Medicine and Geriatric Residents

3/9/10 Problem Solving Therapy Philadelphia VA Behavioral Health Lab Nationwide VA Educational Teleconference

4/14/10 Late Life Schizophrenia UPMC School of Medicine 3

rd year medical student clerkship

4/19/10 Problem Solving Therapy Uniontown Community Based Outpatient Clinic, VA Pittsburgh Health Care System

5/7/10 The Overlap of Depression and Cognitive Decline VA Pittsburgh Health Care System Geriatric Research Education and Clinical Center Seminar

12/17/10 Late Life Schizophrenia. UPMC Geriatric Psychiatry Fellowship Integrated Lecture Series.

10/28/11 Dealing with Dementia VAPHS GRECC lecture series

4/13/12 Late Life Schizophrenia. UPMC Geriatric Psychiatry Fellowship Integrated Lecture Series.

10/23/12

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Dementia Diagnosis UPMC Medical Students Canterbury Hospital

11/9/12 Managing Dementia VAPHS GRECC lecture series

11/9/12 Late Life Schizophrenia. UPMC Geriatric Psychiatry Fellowship Integrated Lecture Series.

3/8/13 Dealing with Dementia VAPHS GRECC lecture series

LIST of CURRENT RESEARCH INTERESTS:

CURRENT RESEARCH INTERESTS:

PRIMARY FOCUS:

1. DEPRESSION AND SUICIDAL BEHAVIOR IN PATIENTS WITH SCHIZOPHRENIA

2. LATE LIFE DEPRESSION

SECONDARY RESEARCH INTEREST: NEUROENDOCRINOLOGY OF STRESS REGULATION

SERVICE

University and Medical School Service

1995-2002

Member, Cincinnati VA Research and Development Committee

1997-1999

Member IRB Committee University of Cincinnati College of Medicine

2001-2006

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Alternate Member University of Cincinnati College of Medicine IRB Committee

VA representative for Residency Training Committee to the University of Cincinnati Department of Psychiatry

2005-2006

Committee Member – VA Pharmacy and Therapeutics

Alternate Committee member of the University of Cincinnati IRB

Attending Geropsychiatrist, 7 North - Cincinnati VAMC, Ft Thomas Nursing Home and VA Mental Hygiene Clinic

2007-2008

Alternate Member, Pittsburgh VA Health Care System, Research and Development Committee

2008-2009

Member, Pittsburgh VA Health Care System, Research and Development Committee

2009 – present Member, Pittsburgh VA Research Scientific Evaluation Subcommittee of the Research and Development Committee

2008

Committee Member, Pittsburgh VA Health Care System, Geriatric Education Center, for Developing a Teaching Seminar at the VA Pittsburgh Health Care System on Interpersonal Psychotherapy.

2009 Co-Director, Pittsburgh VA Health Care System, University of Pittsburgh Center for Social and Urban Research, Geriatric Education Center, for Developing a Teaching Seminar at University of Pittsburgh Medical Center (9/11/2009) and Temple University (10/16/2009) on “The Future of Home Based Mental Health Care for the Elderly”.

Co-Director, Pittsburgh VA Health Care System, University of Pittsburgh Center for Social and Urban Research, Geriatric Education Center, for Developing a Teaching Seminar on “Evidence-Based Psychotherapy Interventions for

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Treatment of Depression in the Elderly” (10/19/09) at Erie VA Medical Center, Erie, PA.

2010 Co-Director, Pittsburgh VA Health Care System, Geriatric Education Center, for Developing a Seminar on “Problem Solving Therapy” (4/19/10) at the Uniontown VA Community Based Outpatient Clinics, Uniontown, PA.

Community Service

1997-2001 American Association of Geriatric Psychiatry (AAGP) Annual Meeting, Chair of “Developing your Research Career”

AAGP Annual Meeting Vice-chair 2000 AAGP Annual Meeting Chair 2001

2001

Editor, Special Issue of Peptides devoted to Corticotropin-Releasing Hormone

1995-present

Journal Reviewer for

Clinical Journals:

American Journal of Psychiatry Biological Psychiatry American Journal of Geriatric Psychiatry General Hospital Psychiatry International Journal of Geriatric Psychiatry Journal of Traumatic Stress Psychiatric Services Psychiatry Research Journal of Clinical Psychopharmacology Schizophrenia Research Clinical Schizophrenia and Related Psychosis General Hospital Psychiatry Suicide and Life Threatening Behavior

Basic Journals:

Journal of Neurochemistry Endocrinology

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International Journal of Cancer Journal of Neuroscience Journal of Neuroendocrinology Brain Research Interactive Peptides Brain Research Cellular and Molecular Biology Neuroimmunodulation

2004-2006 Member, Review Committee for VA Merit Review Behavioral Health Study Section

2008-

Scientific Review Committee for American Association for Geriatric Psychiatry 2009 Annual Meeting

Reviewer, NIH Interventions Branch, 2005

Reviewer, Ontario Mental Health Foundation, 2006-2007

Reviewer, VA Merit Review Committee – Neurobiology A, Spring 2010

Reviewer, VA Merit Review Committee - Cellular and Molecular Medicine, Fall 2010, Spring 2011.

Reviewer, VA Merit Review Committee – Neurobiology C; Fall 2010 – present

Reviewer, NIH Beeson K award Review committee, Spring 2010 to present

Scientific Reviewer, 2011 Health Services Research and Development Meeting

Reviewer, VA Health Services Research and Development, Spring 2013