jesse arrives at the clinic, he is 14 months old
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Jesse arrives at the clinic, he is 14 months old. Though he looks normal in many respects his parents are worried about him . Developmental milestones 1-2. Knows a few parts of the body and can point to them when asked YES NO - PowerPoint PPT PresentationTRANSCRIPT
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Jesse arrives at the clinic, he is 14 months old
Though he looks normal in many respects his parents are worried about him
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Developmental milestones 1-2
Knows a few parts of the body and can point to them when askedYES NOFollows simple commands (“Roll the ball”) and understands simple questions (“Where’s your shoe?”)YES NOEnjoys simple stories, songs, and rhymesYES NOPoints to pictures, when named, in booksYES NOAcquires new words on a regular basisYES NOUses some one- or two-word questions (“Where kitty?” or “Go bye-bye?”)YES NOPuts two words together (“More cookie” or “No juice”)YES NOUses many different consonant sounds at the beginning of words
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Attention deficit disorder drugs
Ritalin is a mild central nervous system stimulant.
It affects chemicals in the brain that contribute to hyperactivity and impulse control.
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Jesse’s brain on autopsy
Normal brain
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Coronal section
Normal brain
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Positron Emission Tomography (PET)
18FluorodeoxyglucoseHalf life = 110 minutes
PET scanner
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Positron Emission Tomography (PET)
Horizontal sections
Normal brain Area of abnormalActivity (seizure)
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Positron Emission Tomography (PET)
Horizontal sections
Normal brain Area of abnormalactivity in Alzheimer’spatient
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Positron Emission Tomography (PET)
Horizontal sections
Brain showing tumor
Area of abnormalactivity (seizure)
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MAGNETIC RESONANCE IMAGING (MRI)
Hydrogen atomMRI scanner
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FUNCTIONAL MAGNETIC RESONANCE IMAGING (fMRI)
Hemoglobin: Oxygenation changesFe 2+ to Fe 3+ MRI scanner
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MAGNETIC RESONANCE IMAGING (MRI)
Corpus callosum
Structural MRI Functional MRI(Subject read one word)
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MAGNETIC RESONANCE IMAGING (MRI)
TumorAgenesis of the corpus callosum
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Electroencephalopathy (EEG)
Cap
Leads
Amplifier
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Electroencephalopathy (EEG)
Parietal area betweenelectrodes
Neurons responsibleFor the signal