january 25, 2008. current and future database (ch) indexing vgd_common (jm; 1q) fully implement...

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Page 1: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

January 25, 2008

Page 2: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

Current and Future

Page 3: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level
Page 4: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

Database (CH)

Indexing vgd_common (JM; 1Q) Fully implement Taxonomy tables

(JO, DD; 2Q) Allow subspecies-level taxonomy Fix Dengue Fix HCV

Fully update Pluto.vgd_common with all patches (CH)

Page 5: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level
Page 6: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

Data (CH)

Data releases Data Release 6.4 (JM; 1Q) Data Release 6.5 (SC; 2Q)

Continuous data release (JM; 4Q) Replication between Pluto and Gendb

Databases Automated annotation Correct handling of “missing”

information by web site

Page 7: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

Reference Genomes (CH)

Define Curated strain RefSeq strain

Links from all VOCs orthologs Links to RefSeq and VBRC reference

Page 8: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level
Page 9: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

BLAST (JM)

VBRC BLAST Processes (JM) Reevaluate process of storing all BLAST

data (2Q) Separate BLAST data into new db (2Q)

Add views to vgd_common Reassess BLAST XML Parsing tools

HCV BLAST (JO) Update HCV BLAST db (1Q) Move HCV BLAST from mars to VBRC

(2Q)

Page 10: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

Protein information (JM, SC) Generate all figures on-the-fly

Genome maps (1Q) Hydrophobicity plots (3Q)

Get rid of dependence on GCG (3Q) Display aa location of any motif hit (2Q) Epitopes (SC)

Evaluate HCV epitopes: Why so many (JO) Epitope identification by taxonomy (2Q)

EC numbers (SC; 2Q) Polymerase Protease

Page 11: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

HCV annotation (JO)

HCV genotyping Alignments

Generate View

Trees Generate View

Manual method for genotyping (2Q) Automated genotyping (4Q)

Page 12: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

KDB (DD)

In production (1Q) Tie in with vgd_common (2Q)

Table/field relationships Annotation statistics updates

Page 13: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

UVic annotation pipeline (CH; 2Q) VOCs

Better annotation InterPro

Identify location DO NOT delete genome/gene IDs

Page 14: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

Curation (EK; continuous) Gene names

Consistent Meaningful Coordinate names in KDB with

vgd_common (CH, DD)

Page 15: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

Controlled vocabularies (JO; 2008-2009) GO SO

Page 16: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level
Page 17: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

Genome search and display(JO; 2008-2009) New search interface

Combine genome and gene Visualization

Genome maps Search results Variation Features

Epitopes Functional motifs

Page 18: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level
Page 19: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

Web site (JM)

Genome maps (1Q) Create all on-the-fly

Add contract # to web site (1Q) Update documents (1Q)

July 2007 Progress Report Bug fixes (2Q) How well do filters handle taxonomy

updates/changes? (CH, DD; 2Q)

Page 20: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level
Page 21: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

Help (JM, CG)

Online (1Q) Tutorials (3Q)

Page 22: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level
Page 23: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

IOWG (EJL, CH)

Annotation Lists (1Q) GFF3 File formats (2Q)

Properly annotate mature peptides Properly annotate RNA processing

Page 24: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

HCV (EJL)

Add LANL HCV advisory members to SWG (1Q)

Genome information (2Q) Contact SLU for data

Page 25: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

ICTVdb (EJL)

Create link-outs (3Q)

Page 26: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

NCBI Interactions (CH)

Links GenBank record parsing

Page 27: January 25, 2008. Current and Future Database (CH)  Indexing vgd_common (JM; 1Q)  Fully implement Taxonomy tables (JO, DD; 2Q)  Allow subspecies-level

Next Group Meeting

February 8th, 2008 2:30 – 4:30 AIDS Center Conference Room, BBRB

Room 256A Topic

KDB Presenter

Don Dempsey