irvine scientific material safety data … safety data sheet version: 02 hepes buffer solution 1 m...

IRVINE SCIENTIFIC Date of Issue: 24/JAN/2011 MATERIAL SAFETY DATA SHEET Version: 02 HEPES Buffer Solution 1 M Revision Date: 24/JAN/2011

9319 HEPES Buffer Solution 1 M of 4

Section 1 – Product & Company Identification Product Name: HEPES Buffer Solution 1 M Product Number: 9319 Company: Irvine Scientific 2511 Daimler Street Santa Ana, California 92705-5588 Technical Phone Number: 800-437-5706 Fax Number: 949-261-6522 Emergency Phone Number: 800-437-5706 E-Mail Address: [email protected] Section 2 – Hazards Identification This mixture is classified as not hazardous according to regulation (EC) 1272/2008 [GHS]. HMIS Rating: Health = 0, Fire = 0, Reactivity = 0 NFPA Rating: Health =0, Flammability = 0, Reactivity = 0 Section 3 – Composition/Information on Ingredients Product name CAS Number EC Number Annex I Number HEPES Buffer Solution 1 M None None None HEPES Acid 7365-45-9 None None HEPES, Sodium Salt 75277-39-3 None None Section 4 – First Aid Measures General information: When in doubt or if symptoms are observed, get medical advice. In case of inhalation: Remove casualty to fresh air and keep warm and at rest. If breathing is irregular

or stopped, administer artificial respiration. In case of skin contact: Wash immediately with soap and water. In case of skin irritation, consult a

physician. In case of eye contact: Rinse immediately carefully and thoroughly with eye-bath or water. In case of ingestion: Rinse mouth thoroughly with water. Section 5 – Fire Fighting Measures Suitable Extinguishing Media: Water, foam, extinguishing powder, carbon dioxide (CO2

Extinguishing media which must not be used for safety reasons: None )

In case of fire may be liberated: Emits toxic fumes under fire conditions Special protective equipment for fire-fighters: Wear a self-contained breathing apparatus Section 6 – Accidental Release Measures



Personal precautions: Provide adequate ventilation Environmental Precautions: None Methods for cleaning up:

Suitable material for diluting or neutralizing: water Suitable material for taking up: sand, absorbing material, earth

Section 7: Handling & Storage Handling: Avoid inhalation. Avoid skin contact. Avoid eye contact. Storage:

Storage temperature: 2-8o

Protect against: Light C

Conditions: Keep tightly closed Section 8 – Exposure controls / Personal protection Exposure limit values: Not available Exposure Controls:

Product related measures to prevent exposure: Observe the expiry date Personal protection equipment:

Respiratory protection: No personal respiratory protective equipment normally required. Where protection is desired, use multi-purpose combination (US) or type ABEK (EN14387) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Hand protection: disposable gloves Eye protection: Eye glasses Protective clothing: Lab coat General health and safety measures: Avoid contact with skin, eye and clothing. Remove

contaminated, saturated clothing. Wash contaminated clothing prior to re-use. Section 9 – Physical and Chemical Properties General:

Physical State: Liquid Color: Clear, Colorless Odor: Characteristic

Important health, safety and environmental information:

pH value: Neutral Melting point / melting range: Not available Solidifying point: Not available Freezing point: Not available Boiling point: Not available Vapor pressure: Not available Density: Not available Bulk density: Not available



Solubility: Water Viscosity: Not available Flow time: Not available

Other information:

Solvent Content (%): 0% Section 10 – Stability and Reactivity Stability: Stable Conditions to avoid: Temperatures below 0o

Materials to avoid: Oxidizing agents, Strong; Reducing agent, strong C

Hazardous decomposition products: Unknown Section 11 – Toxicological Information Toxicokinetics metabolism and distribution: Not determined Toxicological effects: Not determined Irritant and corrosive effects: May cause irritation to skin, eyes, or mucous membranes. Section 12 – Ecological Information Ecotoxicity: Not determined Mobility: Not determined Persistence and degradability: Not available Biodegradation: Evidence exists of biodegradation processes Bioaccumulative potential: Does not significantly accumulate in organisms. Overall evaluation: On the basis of existing data about the elimination/degradation and

bioaccumulation, potential longer term damage to the environment is unlikely. BOD5 and COD: Not available Section 13 – Disposal Considerations Dispose according to legislation. Consult the appropriate local waste disposal expert about waste disposal. Section 14 – Transportation Information Land transport (ADR/RID): Not a dangerous good in sense of this transport regulation. Inland water ways transport (ADN): Not a dangerous good in sense of this transport regulation. Sea transport (IMDG): Not a dangerous good in sense of this transport regulation. Air transport (ICAO-TP / IATA-DGR): Not a dangerous good in sense of this transport regulation. DOT Classification: Not a DOT controlled material (United States) Section 15 – Regulatory Information For this mixture a chemical safety assessment has not been carried out.



Germany: WGK: 1 - Self-Assessment

Listed European Food Additive: None of the ingredients are on the inventory, and may be exempt from listing. TSCA Inventory List: None of the ingredients are on the inventory list. CERCLA: Not Available SARA Title III: Not Available Foreign Inventory List: Not Available Section 16 – Other Information Irvine Scientific supplies Material Safety Data Sheets (MSDS) for products you have purchased. The regulations promulgated by OSHA for Hazard Communication, 29 CFR 1910.1200, and 1907/2006/EC and are used as the basis for the development of the MSDS. All information is offered in good faith as accurate, but is furnished without guaranty. No claim is made that the information is all inclusive, and should only be used as a guide. Irvine Scientific shall not be held liable for any damage resulting from handling or from contact with the product. Federal and California Hazard Communication regulations stipulate that any food, food additive, color additive, drug, cosmetic or medical or veterinary device or product, including materials intended for use as ingredients in such products (e,g, flavors and fragrances), as such terms are defined in the Federal Food, Drug, and Cosmetic Act (21 USC 301 et seq) or the Virus-Serum-Toxic Act of 1913 (21 USC 151 et seq,), and regulations issued under those Acts, when they are subject to the labeling requirements under those Acts by either the Food and Drug Administration or the Department of Agriculture do not require labeling.

Material Safety Data SheetLaemmli SDS-Sample Buffer, reducing (2X)

1: Chemical Product and Company IdentificationProduct Name : Laemmli SDS-Sample Buffer, reducing (2X)

Catalog Code : 10570030CAS# : Not available.RTECS# : Not available.TSCA : Not available.CI# : Not available.Chemical Name : Laemmli SDS-Sample Buffer, reducing (2X)

Chemical Formula : Not available.

Contact Information : bioWORLD4150 Tuller RoadSuite 228Dublin,OH 43017,USAPhone Number : 614-792-8680Fax Number : 614-792-8685Order Online : http://www.bio-world.com/E-mail : [email protected] Case of a chemical emergency:Contact local hospital For non-emergency assistance:Call 1-800-860-9729

Synonym : Not available.

2: Composition and Information on IngredientsName CAS# % of weightGlycerol 56-81-5 <20%2-mercaptoethanol 60-24-2 <10%Sodium lauryl sulfate 151-21-3 <4%Tris(hydroxymethyl)aminomethane hydrochloride 1185-53-1 <1.51%Bromophenol blue 115-39-9 <0.004%Water 7732-18-5 64.486%

Toxicological Data : Glycerol:Oral (Rat) LD50: 12600 mg/kgOral (Guinea pig) LD50: 7750 mg/kgOral (Human) TDLo: 1428 mg/kgIntraperitoneal (Rat) LD50: 4420 mg/kgSubcutaneous (Rat) LD50: 100 mg/kgIntravenous (Rat) LD50: 5566 mg/kgOral (Mouse) LD50: 4090 mg/kgIntraperitoneal (Mouse) LD50: 8700 mg/kgSubcutaneous (Mouse) LD50: 91 mg/kgIntravenous (Mouse) LD50: 4250 mg/kg2-MERCAPTOETHANOL:Oral (rat) LD50: 244 mg/kg Inhalation (mouse) LC50: 13200 mg/m3Dermal (rabbit) LD50: 150 mg/kgOral (Rat) LD50: 131 mg/kg *Dermal (Rabbit) LD50: 251 mg/kg *Inhalation (Rat) LC50: 2000 mg/m3/4h *SODIUM LAURYL SULFATE:Oral (rat) LD50: 1288 mg/kg

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3: Hazards IdentificationPotential Acute Health Effects : May be harmful if inhaled or swallowed. May cause respiratory tract irritation. Skin May be

harmful if absorbed through skin. May cause skin irritation or eye irritation.

Potentials Chronic Health Effects :

Carcinogenic Effects : No component of this product present at levels greater than or equal to 0.1% is identified as probable,

possible or confirmed human carcinogen by IARC or ACGIH.

Mutagenic Effects : Not available.

Teratogenic Effects : Not available.

Developmental Toxicity : Not available.

4: First Aid Measures Eye Contact : In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate

flushing by separating the eyelids with fingers. Call a physician.

Skin Contact : In case of contact, immediately wash skin with soap and copious amounts of water. Call a physician if irritation

persists.

Serious Skin Contact : Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek

medical attention.

Inhalation : If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Serious Inhalation : If breathed in, move person into fresh air. If not breathing give artificial respiration. Get medical attention.

Ingestion : Never give anything by mouth to an unconscious person. Rinse mouth with water. Call a physician.

Serious Ingestion : If swallowed, wash out mouth with water provided person is conscious. Call a physician.

5: Fire and Explosion DataFlammability of the Product : Not available.

Auto-Ignition Temperature : Not available.

Flash Points : Not available.

Flammable Limits : Not available.

Product of Combustion : Carbon oxides, nitrogen oxides (NOx), Sulphur oxides, Hydrogen chloride gas, Sodium oxides

Fire Hazards in Presence of Various Substances : Not available.

Explosion Hazards in Presence of Various Substances : Not available.

Fire Fighting Media and Instructions :

SMALL FIRE : Dry chemical powder.

LARGE FIRE : Water spray,Carbon dioxide, dry chemical powder, or appropriate foam.

Special Remarks on Fire Hazards : Not available.

Special Remarks on Explosion Hazards : Not available.

6 : Accidental Release MeasuresSmall Spill : Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after

material pickup is complete.

Large Spill : Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on

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the contaminated surface and allow to evacuate through the sanitary system.

7: Handling and StoragePrecautions : Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire

protection.

Storage : Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are

opened must be carefully resealed and kept upright to prevent leakage. Recommended storage temperature: -20 °C

8: Exposure Controls/Personal ProtectionEngineering Controls : Use mechanical exhaust or laboratory fumehood to avoid exposure.

Personal Protection : Respiratory : Government approved respirator.

Hand: Chemical resistant gloves.

Eye: Safety glasses.

Personal Protection in Case of a Large Spill : Splash goggles. Full suit. Boots. Dust respirator. Gloves.

Exposure Limits : Not available.

9: Physical and Chemical PropertiesPhysical State and Appearance : Liquid

Odor : Unpleasant

Taste : Not available.

Molecular Weight : Not available.

Color : Colourless

PH Value : Not available.

Boiling Point : Not available.

Melting Point : Not available.

Critical Temperature : Not available.

Specific Gravity : Not available.

Vapour Pressure : Not available.

Vapor Density : Not available.

Volatility : Not available.

Odor Threshold:Not available.

Water/Oil Dist. Coeff : Not available.

Ionicity(in Water) : Not available.

Dispersion Properties : Not available.

Solubility : Soluble in water.

10: Stability and Reactivity DataStability : Stable under recommended storage conditions.

Instability Temperature : Not available.

Conditions of Instability : Not available.

Incompatibility with various substances : Strong bases, Bases, Oxidizing agents, Strong oxidizing agents, Metals

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Corrosivity : Not available.

Special Remarks on Reactivity : Not available.

Special Remarks on Corrosivity : Not available.

Polymerization : Will not occur.

11:Toxicological InformationRoutes of Entry : Eye contact. Inhalation. Ingestion.

Toxicity to Animals : GLYCEROL:

Oral (Rat) LD50: 12600 mg/kg

Oral (Guinea pig) LD50: 7750 mg/kg

Oral (Human) TDLo: 1428 mg/kg

Intraperitoneal (Rat) LD50: 4420 mg/kg

Subcutaneous (Rat) LD50: 100 mg/kg

Intravenous (Rat) LD50: 5566 mg/kg

Oral (Mouse) LD50: 4090 mg/kg

Intraperitoneal (Mouse) LD50: 8700 mg/kg

Subcutaneous (Mouse) LD50: 91 mg/kg

Intravenous (Mouse) LD50: 4250 mg/kg

2-MERCAPTOETHANOL:

Oral (rat) LD50: 244 mg/kg Skin (rabbit): 10 mg/24h (open)

Inhalation (mouse) LC50: 13200 mg/m3- Eye (rabbit): 1 mg - SEVERE

Dermal (rabbit) LD50: 150 mg/kg

Oral (Rat) LD50: 131 mg/kg *

Dermal (Rabbit) LD50: 251 mg/kg *

Inhalation (Rat) LC50: 2000 mg/m!/4h *

SODIUM LAURYL SULFATE:

Oral (rat) LD50: 1288 mg/kg

Irritation:

Skin (human): 25 mg/24 hr - Mild

Skin (None) None: rabbit None 50 mg/24 Eye (rabbit) 10: mg

Eye (None) None: rabbit None 250 ug Skin (rabbit):25 mg/24

hr-Moderate

Eye (rabbit):100 mg/24 hr-Moderate

Chronic Effects on Humans : Skin Contact: May cause skin irritation.

Skin Absorption: May be harmful if absorbed through the skin.

Eye Contact: May cause eye irritation.

Inhalation: May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.

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Ingestion: May be harmful if swallowed.

Other Toxic Effects on Humans : Not available.

Special Remarks on Toxicity to Animals : Not available.

Special Remarks on Chronic Effects on Humans : Burning sensation, Cough, wheezing, laryngitis, Shortness of breath,

Headache, Weakness, Nausea,

Unconsciousness. Kidney - Irregularities - Based on Human Evidence (Glycerol)

Liver - Irregularities - Based on Human Evidence (Sodium dodecyl sulphate)

Special Remarks on other Toxic Effects on Humans : Not available.

12: Ecological InformationEcotoxicity : Not available.

BOD5 and COD : Not available.

Product of Biodegradation : Not available.

Toxicity of the Products of Biodegradation : Not available.

Special Remarks on the Products of Biodegradation : Not available.

13: Disposal ConsiderationsWaste Disposal : Waste must be disposed of in accordance with federal, state and local environmental control regulations.

14: Transport InformationDOT Classification :

UN number: 3082; Class:9; PG:III;

UN proper shipping name: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID, N.O.S.(2-Mercaptoethanol);

IMDG Marine pollutant: Yes;

IATA Classification :




IMDG Classification :




Identification : Not available.

Special Provisions for Transport : Not available.

15: Other Regulatory InformationFederal and State Regulations : Not available.

Other Regulations : Classification according to Regulation (EC) No 1272/2008:

Acute toxicity, Oral (Category 4), H302

Acute toxicity, Inhalation (Category 4), H332

Acute toxicity, Dermal (Category 3), H311

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Skin irritation (Category 2), H315

Serious eye damage (Category 1), H318

Skin sensitisation (Category 1), H317

Acute aquatic toxicity (Category 1), H400

Chronic aquatic toxicity (Category 1), H410

Other Classifications : CONSIDERED A HAZARDOUS SUBSTANCE ACCORDING TO OSHA 29 CFR 1910.1200.

WHMIS(Canada) : D2B- Toxic materials causing other serious effects.

DSCL(EEC) : Classification according to EU Directives 67/548/EEC or 1999/45/EC:

Xn Harmful

N Dangerous for the environment

R-phrase(s)

R20/21/22 Harmful by inhalation, in contact with skin and if swallowed.

R41 Risk of serious damage to eyes.

R43 May cause sensitisation by skin contact.

R50/53 Very toxic to aquatic organisms, may cause long-term adverse effects in

the aquatic environment.

S-phrase(s)

S26 In case of contact with eyes, rinse immediately with plenty of water and

seek medical advice.

S36/37/39 Wear suitable protective clothing, gloves and eye/face protection.

S61 Avoid release to the environment.

HMIS(U.S.A) :

Health Hazard : 3

Fire Hazard : 0

Reactivity : 0

Personal Protection : Not available.

National Fire Protection Association (U.S.A) :

Health : 3

Flammability : 0

Reactivity : 0

Specific hazard : Not available.

Protective Equipment : Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Safety

goggles.

16: Other InformationReferences : Not available.

Other Special Considerations : Created : Not available. Last Updated : 06-24-2014 4:00:00 PM

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DisclaimerThis product is offered by bio-WORLD for research, laboratory or further manufacturing use. Not for human use or consumption.The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty ofmerchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Usersshould make their own investigations to determine the suitability of the information for their particular purposes. In no event shall bio-WORLD beliable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplarydamages, howsoever arising, even if bio-WORLD has been advised of the possibility of such damages.

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Material Safety Data SheetEthyl Alcohol 190 Proof MSDS

Section 1: Chemical Product and Company Identification

Product Name: Ethyl Alcohol 190 Proof

Catalog Codes: SLE1036, SLE1609, SLE1288

CAS#: Mixture.

RTECS: Not applicable.

TSCA: TSCA 8(b) inventory: Water; Ethyl alcohol 200Proof

CI#: Not applicable.

Synonym: Ethyl Alcohol 190 Proof

Chemical Formula: Not applicable.

Contact Information:Sciencelab.com, Inc.14025 Smith Rd.Houston, Texas 77396US Sales: 1-800-901-7247International Sales: 1-281-441-4400Order Online: ScienceLab.com

CHEMTREC (24HR Emergency Telephone), call:1-800-424-9300

International CHEMTREC, call: 1-703-527-3887

For non-emergency assistance, call: 1-281-441-4400

Section 2: Composition and Information on IngredientsComposition:

Name CAS # % by Weight

Water 7732-18-5 5

Ethyl alcohol 200 Proof 64-17-5 95

Toxicological Data on Ingredients: Ethyl alcohol 200 Proof: ORAL (LD50): Acute: 7060 mg/kg [Rat]. 3450 mg/kg [Mouse].VAPOR (LC50): Acute: 20000 ppm 8 hours [Rat]. 39000 mg/m 4 hours [Mouse].

Section 3: Hazards Identification

Potential Acute Health Effects:Hazardous in case of skin contact (irritant), of eye contact (irritant), . Slightly hazardous in case of skin contact (permeator), ofingestion. Non-corrosive for skin. Non-corrosive to the eyes. Non-corrosive for lungs.

Potential Chronic Health Effects:Slightly hazardous in case of skin contact (sensitizer) CARCINOGENIC EFFECTS: Classified PROVEN by State of CaliforniaProposition 65 [Ethyl alcohol 200 Proof]. Classified A4 (Not classifiable for human or animal.) by ACGIH [Ethyl alcohol 200Proof]. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. [Ethyl alcohol 200 Proof]. Mutagenic for bacteriaand/or yeast. [Ethyl alcohol 200 Proof]. TERATOGENIC EFFECTS: Classified PROVEN for human [Ethyl alcohol 200 Proof].DEVELOPMENTAL TOXICITY: Classified Development toxin [PROVEN] [Ethyl alcohol 200 Proof]. Classified Reproductivesystem/toxin/female, Reproductive system/toxin/male [POSSIBLE] [Ethyl alcohol 200 Proof]. The substance is toxic to blood,the reproductive system, liver, upper respiratory tract, skin, central nervous

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Section 4: First Aid Measures

Eye Contact:Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelidsopen. Cold water may be used. Get medical attention.

Skin Contact:In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminatedclothing and shoes. Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medicalattention.

Serious Skin Contact:Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention.

Inhalation:If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medicalattention if symptoms appear.

Serious Inhalation:Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. Ifbreathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek medicalattention.

Ingestion:Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconsciousperson. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.

Serious Ingestion: Not available.

Section 5: Fire and Explosion Data

Flammability of the Product: Flammable.

Auto-Ignition Temperature: The lowest known value is 363°C (685.4°F) (Ethyl alcohol 200 Proof).

Flash Points: CLOSED CUP: 18.5°C (65.3°F).(estimated)

Flammable Limits: The greatest known range is LOWER: 3.3% UPPER: 19% (Ethyl alcohol 200 Proof)

Products of Combustion: These products are carbon oxides (CO, CO2).

Fire Hazards in Presence of Various Substances:Highly flammable in presence of open flames and sparks, of heat. Slightly flammable to flammable in presence of oxidizingmaterials. Non-flammable in presence of shocks, of reducing materials, of combustible materials, of organic materials, ofmetals, of acids, of alkalis.

Explosion Hazards in Presence of Various Substances:Slightly explosive in presence of open flames and sparks, of heat, of oxidizing materials, of acids. Non-explosive in presenceof shocks.

Fire Fighting Media and Instructions:Flammable liquid, soluble or dispersed in water. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use alcohol foam,water spray or fog.

Special Remarks on Fire Hazards:Containers should be grounded. CAUTION: MAY BURN WITH NEAR INVISIBLE FLAME Vapor may travel considerabledistance to source of ignition and flash back. May form explosive mixtures with air. Contact with Bromine pentafluoride is likelyto cause fire or explosion. Ethanol ignites on contact with chromyl chloride. Ethanol ignites on contact with iodine heptafluoridegas. It ignites than explodes upon contact with nitrosyl perchlorate. Additon of platinum black catalyst caused ignition. (Ethylalcohol 200 Proof)

Special Remarks on Explosion Hazards:Ethanol has an explosive reaction with the oxidized coating around potassium metal. Ethanol ignites and then explodes oncontact with acetic anhydride + sodium hydrosulfate (ignites and may explode), disulfuric acid + nitric acid, phosphorous(III)

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oxide platinum, potassium-tert-butoxide+ acids. Ethanol forms explosive products in reaction with the following compound :ammonia + silver nitrate (forms silver nitride and silver fulminate), iodine + phosphorus (forms ethane iodide), magnesiumperchlorate (forms ethyl perchlorate), mercuric nitrate, nitric acid + silver (forms silver fulminate) silver nitrate (forms ethylnitrate) silver(I) oxide + ammonia or hydrazine (forms silver nitride and silver fulminate), sodium (evolves hydrogen gas).Sodium Hydrazide + alcohol can produce an explosion. Alcohols should not be mixed with mercuric nitrate, as explosivemercuric fulminate may be formed. May form explosive mixture with manganese perchlorate + 2,2-dimethoxypropane. Additionof alcohols to highly concentrate hydrogen peroxide forms powerful explosives. Explodes on contact with calcium hypochloriteVapor may explode if ignited in an enclosed area. Containers may explode when heated or involved in a fire. (Ethyl alcohol200 Proof)

Section 6: Accidental Release Measures

Small Spill:Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container.

Large Spill:Flammable liquid. Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb with DRY earth,sand or other non-combustible material. Do not touch spilled material. Prevent entry into sewers, basements or confinedareas; dike if needed. Be careful that the product is not present at a concentration level above TLV. Check TLV on the MSDSand with local authorities.

Section 7: Handling and Storage

Precautions:Keep locked up.. Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Donot ingest. Do not breathe gas/fumes/ vapor/spray. Wear suitable protective clothing. In case of insufficient ventilation, wearsuitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoidcontact with skin and eyes. Keep away from incompatibles such as oxidizing agents, acids, alkalis, moisture.

Storage:Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly closed andsealed until ready for use. Avoid all possible sources of ignition (spark or flame). Do not store above 23°C (73.4°F).

Section 8: Exposure Controls/Personal Protection

Engineering Controls:Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respectivethreshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location.

Personal Protection:Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.

Personal Protection in Case of a Large Spill:Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoidinhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling thisproduct.

Exposure Limits:Ethyl alcohol 200 Proof TWA: 1900 (mg/m3) from OSHA (PEL) [United States] TWA: 1000 (ppm) from OSHA (PEL) [UnitedStates] TWA: 1900 (mg/m3) from NIOSH [United States] TWA: 1000 (ppm) from NIOSH [United States] TWA: 1000 (ppm)[United Kingdom (UK)] TWA: 1920 (mg/m3) [United Kingdom (UK)] TWA: 1000 STEL: 1250 (ppm) [Canada] Consult localauthorities for acceptable exposure limits.

Section 9: Physical and Chemical Properties

Physical state and appearance: Liquid.

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Odor:Alcohol like. Mild to strong. Like wine or whiskey; Ethereal, vinous. Pleasant.

Taste: Burning. Pungent.

Molecular Weight: Not applicable.

Color: Clear Colorless.

pH (1% soln/water): Neutral.

Boiling Point: The lowest known value is 78.5°C (173.3°F) (Ethyl alcohol 200 Proof). Weighted average: 79.58°C (175.2°F)

Melting Point: May start to solidify at -114.1°C (-173.4°F) based on data for: Ethyl alcohol 200 Proof.

Critical Temperature: The lowest known value is 243°C (469.4°F) (Ethyl alcohol 200 Proof).

Specific Gravity: Weighted average: 0.8 (Water = 1)

Vapor Pressure: The highest known value is 5.7 kPa (@ 20°C) (Ethyl alcohol 200 Proof). Weighted average: 5.53 kPa (@20°C)

Vapor Density: The highest known value is 1.59 (Air = 1) (Ethyl alcohol 200 Proof). Weighted average: 1.54 (Air = 1)

Volatility: Not available.

Odor Threshold: 100 ppm

Water/Oil Dist. Coeff.: Not available.

Ionicity (in Water): Not available.

Dispersion Properties: See solubility in water, methanol, diethyl ether, acetone.

Solubility:Easily soluble in cold water, hot water, methanol, diethyl ether. Soluble in acetone.

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Incompatible materials, heat, sources of ignition.

Incompatibility with various substances: Reactive with oxidizing agents, acids, alkalis.

Corrosivity: Non-corrosive in presence of glass.

Special Remarks on Reactivity:Ethanol rapidly absorbs moisture from the air. Can react vigorously with oxiders. The following oxidants have beendemonstrated to undergo vigorous/explosive reaction with ethanol: barium perchlorate, bromine pentafluoride, calciumhypochlorite, chloryl perchlorate, chromium trioxide, chromyl chloride, dioxygen difluoride, disulfuryl difluoride, fluorine nitrate,hydrogen peroxide, iodine heptafluoride, nitric acid nitrosyl perchlorate, perchloric acid permanganic acid, peroxodisulfuricacid, potassium dioxide, potassium perchlorate, potassium permanganate, ruthenium(VIII) oxide, silver perchlorate, silverperoxide, uranium hexafluoride, uranyl perchlorate. Ethanol reacts violently/expodes with the following compounds: acetylbromide (evolves hydrogen bromide) acetyl chloride, aluminum, sesquibromide ethylate, ammonium hydroxide & silveroxide, chlorate, chromic anhydride, cyanuric acid + water, dichloromethane + sulfuric acid + nitrate (or) nitrite, hydrogenperoxide + sulfuric acid, iodine + methanol + mercuric oxide, manganese perchlorate + 2,2-dimethoxy propane, perchlorates,permanganates + sulfuric acid, potassium superoxide, potassium tert-butoxide, silver & nitric acid, silver perchlorate, sodiumhydrazide, sulfuric acid + sodium dichromate, tetrachlorisilane + water. Ethanol is also incompatible with platinium, andsodium. No really safe conditions exist under which ethyl alcohol and chlorine oxides can be handled. Reacts vigorously withacetyl chloride (Ethyl alcohol 200 Proof)

Special Remarks on Corrosivity: Not available.

Polymerization: Will not occur.

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Section 11: Toxicological Information

Routes of Entry: Absorbed through skin. Eye contact. Inhalation. Ingestion.

Toxicity to Animals: Acute oral toxicity (LD50): 3632 mg/kg (Mouse) (Calculated value for the mixture).

Chronic Effects on Humans:CARCINOGENIC EFFECTS: Classified PROVEN by State of California Proposition 65 [Ethyl alcohol 200 Proof]. ClassifiedA4 (Not classifiable for human or animal.) by ACGIH [Ethyl alcohol 200 Proof]. MUTAGENIC EFFECTS: Mutagenicfor mammalian somatic cells. [Ethyl alcohol 200 Proof]. Mutagenic for bacteria and/or yeast. [Ethyl alcohol 200 Proof].TERATOGENIC EFFECTS: Classified PROVEN for human [Ethyl alcohol 200 Proof]. DEVELOPMENTAL TOXICITY:Classified Development toxin [PROVEN] [Ethyl alcohol 200 Proof]. Classified Reproductive system/toxin/female, Reproductivesystem/toxin/male [POSSIBLE] [Ethyl alcohol 200 Proof].

Other Toxic Effects on Humans:Hazardous in case of skin contact (irritant), of inhalation. Slightly hazardous in case of skin contact (permeator), of ingestion.

Special Remarks on Toxicity to Animals:Lowest Published Dose/Conc: LDL[Human] - Route: Oral; Dose: 1400 mg/kg LDL[Human child] - Route: Oral; Dose: 2000 mg/kg LDL[Rabbit] - Route: Skin; Dose: 20000 mg/kg (Ethyl alcohol 200 Proof)

Special Remarks on Chronic Effects on Humans:May affect genetic material (mutagenic) Causes adverse reproductive effects and birth defects (teratogenic) , based onmoderate to heavy consumption. May cause cancer based on animal data. Human: passes through the placenta, excreted inmaternal milk. (Ethyl alcohol 200 Proof)

Special Remarks on other Toxic Effects on Humans:Acute potential health effects: Skin: causes skin irritation Eyes: causes eye irritation Ingestion: May cause gastrointestinal tractirritation with nausea, vomiting, diarrhea, and alterations in gastric secretions. May affect behavior/central nervous system(central nervous system depression - amnesia, headache, muscular incoordination, excitation, mild euphoria, slurred speech,drowsiness, staggaring gait, fatigue, changes in mood/personality, excessive talking, dizziness, ataxia, somnolence, coma/narcosis, hallucinations, distorted perceptions, general anesthetic), peripherial nervous system (spastic paralysis)vision(diplopia). Moderately toxic and narcotic in high concentrations. May also affect metabolism, blood, liver, respiration (dyspnea),and endocrine system. May affect respiratory tract, cardiovascular(cardiac arrhythmias, hypotension), and urinary systems.Inhalation: May cause irritation of the respiratory tract and affect behavior/central nervous system with symptoms similarto ingestion. Chronic Potential Health Effects: Skin: Prolonged or repeated skin contact may casue dermatitis, an allergicreaction. Ingestion: Prolonged or repeated ingestion will have similiar effects as acute ingestion. It may also affect the brain.(Ethyl alcohol 200 Proof)

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation:Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.

Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.

Special Remarks on the Products of Biodegradation: Not available.

Section 13: Disposal Considerations

Waste Disposal:Waste must be disposed of in accordance with federal, state and local environmental control regulations.

Section 14: Transport Information

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DOT Classification: CLASS 3: Flammable liquid.

Identification: : Ethanol (Ethyl alcohol 200 Proof) UNNA: 1170 PG: II

Special Provisions for Transport: Not available.

Section 15: Other Regulatory Information

Federal and State Regulations:California prop. 65: This product contains the following ingredients for which the State of California has found to causecancer, birth defects or other reproductive harm, which would require a warning under the statute: Ethyl alcohol 200 Proof (inalcoholic beverage) California prop. 65: This product contains the following ingredients for which the State of California hasfound to cause birth defects which would require a warning under the statute: Ethyl alcohol 200 Proof (in alcoholic beverage)Connecticut hazardous material survey.: Ethyl alcohol 200 Proof Illinois toxic substances disclosure to employee act: Ethylalcohol 200 Proof Rhode Island RTK hazardous substances: Ethyl alcohol 200 Proof Pennsylvania RTK: Ethyl alcohol 200Proof Florida: Ethyl alcohol 200 Proof Minnesota: Ethyl alcohol 200 Proof Massachusetts RTK: Ethyl alcohol 200 ProofMassachusetts spill list: Ethyl alcohol 200 Proof New Jersey: Ethyl alcohol 200 Proof TSCA 8(b) inventory: Water; Ethylalcohol 200 Proof

Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).

Other Classifications:

WHMIS (Canada):CLASS B-2: Flammable liquid with a flash point lower than 37.8°C (100°F). CLASS D-2B: Material causing other toxic effects(TOXIC).

DSCL (EEC):R11- Highly flammable. S7- Keep container tightly closed. S16- Keep away from sources of ignition - No smoking.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 3

Reactivity: 0

Personal Protection: h

National Fire Protection Association (U.S.A.):

Health: 2

Flammability: 3

Reactivity: 0

Specific hazard:

Protective Equipment:Gloves. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respiratorwhen ventilation is inadequate. Splash goggles.

Section 16: Other Information

References: Not available.

Other Special Considerations: Not available.

Created: 10/09/2005 05:28 PM

Last Updated: 05/21/2013 12:00 PM

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The information above is believed to be accurate and represents the best information currently available to us. However, wemake no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assumeno liability resulting from its use. Users should make their own investigations to determine the suitability of the information fortheir particular purposes. In no event shall ScienceLab.com be liable for any claims, losses, or damages of any third party or forlost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab.comhas been advised of the possibility of such damages.

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Material Safety Data SheetEthyl alcohol 200 Proof MSDS


Product Name: Ethyl alcohol 200 Proof

Catalog Codes: SLE2248, SLE1357

CAS#: 64-17-5

RTECS: KQ6300000

TSCA: TSCA 8(b) inventory: Ethyl alcohol 200 Proof


Synonym: Ethanol; Absolute Ethanol; Alcohol; Ethanol200 proof; Ethyl Alcohol, Anhydrous; Ethanol, undenatured;Dehydrated Alcohol; Alcohol

Chemical Name: Ethyl Alcohol

Chemical Formula: CH3CH2OH







Ethyl alcohol 200 Proof 64-17-5 100

Toxicological Data on Ingredients: Ethyl alcohol 200 Proof: ORAL (LD50): Acute: 7060 mg/kg [Rat]. 3450 mg/kg [Mouse].VAPOR (LC50): Acute: 20000 ppm 8 hours [Rat]. 39000 mg/m 4 hours [Mouse].


Potential Acute Health Effects:Hazardous in case of skin contact (irritant), of eye contact (irritant), of inhalation. Slightly hazardous in case of skin contact(permeator), of ingestion.

Potential Chronic Health Effects:Slightly hazardous in case of skin contact (sensitizer). CARCINOGENIC EFFECTS: A4 (Not classifiable for human oranimal.) by ACGIH. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast.TERATOGENIC EFFECTS: Classified PROVEN for human. DEVELOPMENTAL TOXICITY: Classified Development toxin[PROVEN]. Classified Reproductive system/toxin/female, Reproductive system/toxin/male [POSSIBLE]. The substance is toxicto blood, the reproductive system, liver, upper respiratory tract, skin, central nervous system (CNS). Repeated or prolongedexposure to the substance can produce target organs damage.

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Eye Contact:Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelidsopen. Cold water may be used. Get medical attention.



Inhalation:If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medicalattention if symptoms appear.






Auto-Ignition Temperature: 363°C (685.4°F)

Flash Points: CLOSED CUP: 12.78°C (55°F). OPEN CUP: 17.78°C (64°F) (Cleveland).

Flammable Limits: LOWER: 3.3% UPPER: 19%


Fire Hazards in Presence of Various Substances:Highly flammable in presence of open flames and sparks, of heat. Slightly flammable to flammable in presence of oxidizingmaterials.

Explosion Hazards in Presence of Various Substances:Risks of explosion of the product in presence of mechanical impact: Not available. Slightly explosive in presence of openflames and sparks, of heat, of oxidizing materials, of acids.


Special Remarks on Fire Hazards:Containers should be grounded. CAUTION: MAY BURN WITH NEAR INVISIBLE FLAME Vapor may travel considerabledistance to source of ignition and flash back. May form explosive mixtures with air. Contact with Bromine pentafluoride is likelyto cause fire or explosion. Ethanol ignites on contact with chromyl chloride. Ethanol ignites on contact with iodine heptafluoridegas. It ignites than explodes upon contact with nitrosyl perchlorate. Additon of platinum black catalyst caused ignition.

Special Remarks on Explosion Hazards:Ethanol has an explosive reaction with the oxidized coating around potassium metal. Ethanol ignites and then explodes oncontact with acetic anhydride + sodium hydrosulfate (ignites and may explode), disulfuric acid + nitric acid, phosphorous(III)oxide platinum, potassium-tert-butoxide+ acids. Ethanol forms explosive products in reaction with the following compound :

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ammonia + silver nitrate (forms silver nitride and silver fulminate), iodine + phosphorus (forms ethane iodide), magnesiumperchlorate (forms ethyl perchlorate), mercuric nitrate, nitric acid + silver (forms silver fulminate) silver nitrate (forms ethylnitrate) silver(I) oxide + ammonia or hydrazine (forms silver nitride and silver fulminate), sodium (evolves hydrogen gas).Sodium Hydrazide + alcohol can produce an explosion. Alcohols should not be mixed with mercuric nitrate, as explosivemercuric fulminate may be formed. May form explosive mixture with manganese perchlorate + 2,2-dimethoxypropane. Additionof alcohols to highly concentrate hydrogen peroxide forms powerful explosives. Explodes on contact with calcium hypochlorite



Large Spill:Flammable liquid. Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb with DRY earth,sand or other non-combustible material. Do not touch spilled material. Prevent entry into sewers, basements or confinedareas; dike if needed. Be careful that the product is not present at a concentration level above TLV. Check TLV on the MSDSand with local authorities.


Precautions:Keep locked up.. Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Donot ingest. Do not breathe gas/fumes/ vapor/spray. Wear suitable protective clothing. In case of insufficient ventilation, wearsuitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoidcontact with skin and eyes. Keep away from incompatibles such as oxidizing agents, acids, alkalis, moisture.

Storage:Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly closed andsealed until ready for use. Avoid all possible sources of ignition (spark or flame). Do not store above 23°C (73.4°F).



Personal Protection:Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Use arespirator if the exposure limit is exceeded.


Exposure Limits:TWA: 1900 (mg/m3) from OSHA (PEL) [United States] TWA: 1000 (ppm) from OSHA (PEL) [United States] TWA: 1900 (mg/m3) from NIOSH [United States] TWA: 1000 (ppm) from NIOSH [United States] TWA: 1000 (ppm) [United Kingdom (UK)]TWA: 1920 (mg/m3) [United Kingdom (UK)] TWA: 1000 STEL: 1250 (ppm) [Canada]Consult local authorities for acceptableexposure limits.


Physical state and appearance: Liquid. (Liquid.)

Odor:

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Mild to strong, rather pleasant; like wine or whiskey. Alcohol-like; Ethereal, vinous.

Taste: Pungent. Burning.

Molecular Weight: 46.07 g/mole

Color: Colorless. Clear

pH (1% soln/water): Not available.

Boiling Point: 78.5°C (173.3°F)

Melting Point: -114.1°C (-173.4°F)

Critical Temperature: 243°C (469.4°F)

Specific Gravity: 0.789 (Water = 1)

Vapor Pressure: 5.7 kPa (@ 20°C)

Vapor Density: 1.59 (Air = 1)


Odor Threshold: 100 ppm

Water/Oil Dist. Coeff.: The product is more soluble in water; log(oil/water) = -0.3



Solubility:Easily soluble in cold water, hot water. Soluble in methanol, diethyl ether, acetone.




Conditions of Instability: Incompatible materials, heat, sources of ignition.

Incompatibility with various substances: Reactive with oxidizing agents, acids, alkalis.


Special Remarks on Reactivity:Ethanol rapidly absorbs moisture from the air. Can react vigorously with oxiders. The following oxidants have beendemonstrated to undergo vigorous/explosive reaction with ethanol: barium perchlorate, bromine pentafluoride, calciumhypochlorite, chloryl perchlorate, chromium trioxide, chromyl chloride, dioxygen difluoride, disulfuryl difluoride, fluorine nitrate,hydrogen peroxide, iodine heptafluoride, nitric acid nitrosyl perchlorate, perchloric acid permanganic acid, peroxodisulfuricacid, potassium dioxide, potassium perchlorate, potassium permanganate, ruthenium(VIII) oxide, silver perchlorate, silverperoxide, uranium hexafluoride, uranyl perchlorate. Ethanol reacts violently/expodes with the following compounds: acetylbromide (evolves hydrogen bromide) acetyl chloride, aluminum, sesquibromide ethylate, ammonium hydroxide & silveroxide, chlorate, chromic anhydride, cyanuric acid + water, dichloromethane + sulfuric acid + nitrate (or) nitrite, hydrogenperoxide + sulfuric acid, iodine + methanol + mercuric oxide, manganese perchlorate + 2,2-dimethoxy propane, perchlorates,permanganates + sulfuric acid, potassium superoxide, potassium tert-butoxide, silver & nitric acid, silver perchlorate, sodiumhydrazide, sulfuric acid + sodium dichromate, tetrachlorisilane + water. Ethanol is also incompatible with platinium, andsodium. No really safe conditions exist under which ethyl alcohol and chlorine oxides can be handled. Reacts vigorously withacetyl chloride




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Routes of Entry: Absorbed through skin. Dermal contact. Eye contact. Inhalation. Ingestion.

Toxicity to Animals:WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR EXPOSURE. Acute oraltoxicity (LD50): 3450 mg/kg [Mouse]. Acute toxicity of the vapor (LC50): 39000 mg/m3 4 hours [Mouse].

Chronic Effects on Humans:CARCINOGENIC EFFECTS: A4 (Not classifiable for human or animal.) by ACGIH. MUTAGENIC EFFECTS: Mutagenic formammalian somatic cells. Mutagenic for bacteria and/or yeast. TERATOGENIC EFFECTS: Classified PROVEN for human.DEVELOPMENTAL TOXICITY: Classified Development toxin [PROVEN]. Classified Reproductive system/toxin/female,Reproductive system/toxin/male [POSSIBLE]. Causes damage to the following organs: blood, the reproductive system, liver,upper respiratory tract, skin, central nervous system (CNS).

Other Toxic Effects on Humans:Hazardous in case of skin contact (irritant), of inhalation. Slightly hazardous in case of skin contact (permeator), of ingestion.

Special Remarks on Toxicity to Animals:Lowest Published Dose/Conc: LDL[Human] - Route: Oral; Dose: 1400 mg/kg LDL[Human child] - Route: Oral; Dose: 2000 mg/kg LDL[Rabbit] - Route: Skin; Dose: 20000 mg/kg

Special Remarks on Chronic Effects on Humans:May affect genetic material (mutagenic) Causes adverse reproductive effects and birth defects (teratogenic) , based onmoderate to heavy consumption. May cause cancer based on animal data. Human: passes through the placenta, excreted inmaternal milk.

Special Remarks on other Toxic Effects on Humans:Acute potential health effects: Skin: causes skin irritation Eyes: causes eye irritation Ingestion: May cause gastrointestinal tractirritation with nausea, vomiting, diarrhea, and alterations in gastric secretions. May affect behavior/central nervous system(central nervous system depression - amnesia, headache, muscular incoordination, excitation, mild euphoria, slurred speech,drowsiness, staggaring gait, fatigue, changes in mood/personality, excessive talking, dizziness, ataxia, somnolence, coma/narcosis, hallucinations, distorted perceptions, general anesthetic), peripherial nervous system (spastic paralysis)vision(diplopia). Moderately toxic and narcotic in high concentrations. May also affect metabolism, blood, liver, respiration (dyspnea),and endocrine system. May affect respiratory tract, cardiovascular(cardiac arrhythmias, hypotension), and urinary systems.Inhalation: May cause irritation of the respiratory tract and affect behavior/central nervous system with symptoms similarto ingestion. Chronic Potential Health Effects: Skin: Prolonged or repeated skin contact may casue dermatitis, an allergicreaction. Ingestion: Prolonged or repeated ingestion will have similiar effects as acute ingestion. It may also affect the brain.


Ecotoxicity: Ecotoxicity in water (LC50): 14000 mg/l 96 hours [Rainbow trout]. 11200 mg/l 24 hours [fingerling trout].








DOT Classification: CLASS 3: Flammable liquid.

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Identification: : Ethanol UNNA: 1170 PG: II



Federal and State Regulations:California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer,birth defects or other reproductive harm, which would require a warning under the statute: Ethyl alcohol 200 Proof (in alcoholicbeverages) California prop. 65: This product contains the following ingredients for which the State of California has foundto cause birth defects which would require a warning under the statute: Ethyl alcohol 200 Proof (in alcoholic beverages)Connecticut hazardous material survey.: Ethyl alcohol 200 Proof Illinois toxic substances disclosure to employee act: Ethylalcohol 200 Proof Rhode Island RTK hazardous substances: Ethyl alcohol 200 Proof Pennsylvania RTK: Ethyl alcohol 200Proof Florida: Ethyl alcohol 200 Proof Minnesota: Ethyl alcohol 200 Proof Massachusetts RTK: Ethyl alcohol 200 ProofMassachusetts spill list: Ethyl alcohol 200 Proof New Jersey: Ethyl alcohol 200 Proof Tennessee: Ethyl alcohol 200 ProofCalifornia - Directors List of Hazardous Substances (8 CCR 339): Ethyl alcohol 200 Proof TSCA 8(b) inventory: Ethyl alcohol200 Proof

Other Regulations:OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). EINECS: This product is on theEuropean Inventory of Existing Commercial Chemical Substances.


WHMIS (Canada):CLASS B-2: Flammable liquid with a flash point lower than 37.8°C (100°F). CLASS D-2A: Material causing other toxic effects(VERY TOXIC).

DSCL (EEC):R11- Highly flammable. S7- Keep container tightly closed. S16- Keep away from sources of ignition - No smoking.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 3

Reactivity: 0

Personal Protection: E


Health: 2

Flammability: 3

Reactivity: 0

Specific hazard:



References:-SAX, N.I. Dangerous Properties of Indutrial Materials. Toronto, Van Nostrand Reinold, 6e ed. 1984. -Material safety datasheet emitted by: la Commission de la Santé et de la Sécurité du Travail du Québec. -Hawley, G.G.. The CondensedChemical Dictionary, 11e ed., New York N.Y., Van Nostrand Reinold, 1987. -The Sigma-Aldrich Library of Chemical SafetyData, Edition II. HSDB, RTECS, and LOLI databases.

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Created: 10/09/2005 05:28 PM

Last Updated: 05/21/2013 12:00 PM


Seastar Chemicals Inc MSDS – ACETIC ACID, GLACIAL

Page 1 of 6

Material Safety Data Sheet ACETIC ACID, GLACIAL

Print Date: September 2011

SECTION 1 – Chemical Product and Company Identification MSDS Name: ACETIC ACID, GLACIAL MSDS Preparation Date: 09-2011 Supersedes 07-2008, 12-2007, 02-2007, 02-2004, 02-2001 & 02-98

Synonyms: Acetic acid, glacial, Ethanoic acid, methanecarboxylic acid. Chemical Names: DE Essigsäure; ES Ácido acético; FR Acide acétique; IT Acido acetico; NL Azijnzuur. UN / NA Number(s): UN2789 Formula: CH3COOH Molecular Wt: 60.05

Product Numbers: S010601, S020601, S010601-SSNC03, S010601-SSNC04, S010601-SSNC06, S010601-SSNC09, S010601-SSNC41, S010601-SSNC61, S010601-SSNC63, S010601-SSNC65, S010601-SSND13, S010601-SSNG04, S010601-SSNG09, S010601-SSNG41, S010601-SSNG61, S010601-SSNG65, S010601-SSNH43, S010601-SSNQ03, S010601-SSNQ09, S020601-SSNF01, S020601-SSNF02, S020601-SSNF03, S020601-SSNF04, S020601-SSNF05, S020601-SSNF06

Supplier: Seastar Chemicals Inc, 10005 McDonald Park Road, Sidney, BC V8L 5Y2 CANADA Tel: (250) 655-5880, Fax: (250) 655-5888

CANUTEC (CAN): (613)-996-6666

SECTION 2 – Composition/Information on Ingredients Chemical Name Percent CAS # EINECS/ELINCS Acetic Acid, Glacial t99% 64-19-7 200-580-7

SECTION 3 – Hazards Identification EMERGENCY OVERVIEW

Appearance: Acetic acid is a clear, colourless liquid above 16 °C and colourless, icelike crystals below 16 °C. Has a strong, pungent odour of vinegar. Hygroscopic. COMBUSTIBLE LIQUID AND VAPOUR. Vapour is heavier than air and may spread long distances. Distant ignition and flashback are possible. Harmful if inhaled or swallowed. Vapour is irritating to the respiratory tract. May cause lung injury--effects may be delayed. Concentrated solutions are CORROSIVE to eyes and skin. Causes permanent eye damage, including blindness, and skin burns, including tissue death and permanent scarring. May be an aspiration hazard. Swallowing or vomiting of the liquid may result in aspiration into the lungs. Target Organs: Teeth, eyes, skin, mucous membranes. Potential Health Effects Primary Route(s) of Entry: Inhalation and ingestion. Skin contact. Skin absorption. Effects of Acute Exposure: May be fatal by ingestion, inhalation or skin absorption. Corrosive. LD50/LC50: CAS# 64-19-7: Inhalation, mouse: LC50 = 5620 ppm/1H. Oral, rat: LD50 = 3310 mg/kg. Skin, rabbit: LD50 = 1060 mg/kg. Eyes: Concentrated solutions are corrosive and can cause permanent eye damage, including blindness. Skin: The degree of irritation depends on the concentration of acetic acid and the length of exposure. Highly concentrated solutions or pure acetic acid can cause corrosive tissue injury with deep burns, tissue death and permanent scarring. Less concentrated solutions can cause mild to severe irritation. Ingestion: Causes severe corrosive injury to the gastrointestinal tract and stomach. Acetic acid may be aspirated (inhaled into the lungs) during ingestion or vomiting. Aspiration of even a small amount of liquid could result in a life-threatening accumulation of fluid in the lungs. Severe lung damage (edema), respiratory failure, cardiac arrest and death may result. Ingestion is not a typical route of occupational exposure. Inhalation: Accidental inhalation of high concentrations may cause corrosive injury to the respiratory tract, inflammation, nose and throat irritation, shortness of breath, cough, wheezing, and reversible lung injury in people exposed occupationally. Effects may be delayed. Effects of Chronic Exposure: Repeated inhalation may cause pulmonary edema, bronchopneumonia, or chemical pneumonitis. Prolonged or repeated exposure may cause dermatitis, erosion of teeth, conjunctivitis and cumulative systemic injury. To the best of our knowledge, the chronic toxicity of this substance has not been fully investigated.


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SECTION 4 – First Aid Measures Eyes: Flush skin and eyes with copious amounts of water for at least 20-30 minutes, holding lids apart to ensure flushing of the entire surface. Contact with liquid or vapor causes severe burns and possible irreversible eye damage. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 20-30 minutes while removing contaminated clothing and shoes. Wash clothes before reuse. Discard shoes. Ingestion: Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Consult a physician immediately. Never give anything by mouth to an unconscious person. Keep patient warm and quiet. Inhalation: Get medical aid immediately. Remove patient from exposure to fresh air immediately. Administer approved oxygen supply if breathing is difficult. Administer artificial respiration or CPR if breathing has ceased. Call a physician. Symptoms of pulmonary edema can be delayed up to 48 hours after exposure. Notes to Physician: Treat symptomatically and supportively. Consult a doctor and/or the nearest Poison Control Centre for all exposures except minor instance of inhalation or skin contact. Antidote: No specific antidote exists.

SECTION 5 – Fire Fighting Measures General Information: COMBUSTIBLE LIQUID AND VAPOUR. Can form explosive mixtures with air at, or above, 39 °C. Vapour is heavier than air and may travel a considerable distance to a source of ignition and flash back to a leak or open container. Vapours from warm liquid can accumulate in confined spaces, resulting in a flammability and toxicity hazard. Closed containers may rupture violently when heated. NOTE: The fire properties of acetic acid depend upon the strength of the solution. In concentrated form, its properties approach those of glacial acetic acid. Reacts with most metals to form highly flammable hydrogen gas, which can form explosive mixtures with air. Firefighters should wear a positive pressure self-contained respirator (SCBA) and full-body encapsulating chemical protective suit. Extinguishing Media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Use water spray to cool fire-exposed containers or disperse vapours if they have not ignited. Auto-ignition Temperature: 867-869 °F (463-465 °C); also reported as 516 °F (961 °C) Flash Point: 39-43 °F (103-109 °C) (closed cup) NFPA Rating: Health 3; Flammability 2; Instability 0. Explosion Limits: Lower: 4% (also reported as 5.3-5.4%); Upper: 16% (also reported as 19.9%). Special Fire and Explosion Hazards: Flash back along vapour trail may occur; eliminate sources of ignition. Emits toxic fumes under fire conditions. Empty container may contain explosive or flammable residue. Hazardous combustion products – Oxides of carbon.

SECTION 6 – Accidental Release Measures General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Restrict access to area until completion of clean-up. Ensure clean-up is conducted by trained personnel only. Use water spray to dilute spill to a non-flammable mixture. Avoid run-off into storm sewers and ditches which lead to waterways. Extinguish or remove all ignition sources. Provide ventilation. Do not touch spilled material. Contain spill with earth, sand, or absorbent material which does not react with spilled material. Remove liquid by pumps or vacuum equipment. Place in suitable, covered, labelled containers. Steps to be taken in case material is released or spilled: Evacuate. Shut off all sources of ignition. Soak up spill with absorbent material which does not react with spilled chemical. Put material in suitable, covered, labelled containers. Flush area with water. Contaminated absorbent material may pose the same hazards as the spilled product. Waste disposal method: Burn in a chemical incinerator equipped with an after burner and scrubber. According to all applicable regulations. Avoid run-off.

SECTION 7 – Handling and Storage Handling: This material is a CORROSIVE, COMBUSTIBLE LIQUID. Inspect containers for damage or leaks before handling. Immediately report leaks, spills or failures of the engineering controls. Avoid all ignition sources. Use in the smallest possible amounts, in a well-ventilated area, separate from the storage area. Avoid generating vapours or mists. Prevent the release of vapours or mists into the air. Do not use with incompatible materials. See Section 10 for more information. Never return contaminated material to its original container. Keep containers tightly closed when not in use. Empty containers may contain hazardous residues. Never add water to a corrosive. Always add corrosives to COLD water. When mixing with water, stir small amounts in slowly. Never perform any welding, cutting, soldering, drilling or other hot work on an empty vessel, containers or piping until all liquid and vapours have been cleared. Storage: Store in a cool, dry, well-ventilated area, out of direct sunlight and away from heat and ignition sources. Store away from oxidizers and corrosives and other incompatible materials such as most common metals. See Section 10 for more information. Inspect all incoming containers to make sure they are properly labelled and not damaged. Keep quantity stored as small as possible. Keep containers tightly closed. Empty containers may contain hazardous residues. Have appropriate fire extinguishers and spill clean-up equipment in or near storage area.


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SECTION 8 – Exposure Control/Personal Protection Engineering Controls: Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Exposure Limits:

Chemical Name ACGIH NIOSH OSHA Acetic acid, glacial 10 ppm TWA (25 mg/m3 TWA);

15 ppm STEL (37 mg/m3 STEL) 10 ppm TWA (25 mg/m3 TWA); 15 ppm STEL (37 mg/m3 STEL); 50 ppm IDLH

10 ppm TWA (25 mg/m3 TWA)

OSHA Vacated PELs Acetic acid: 10 ppm TWA; 25 mg/m3 TWA. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA’s eye and face protection regulations in 29 CFR 1910.133. Skin: Wear appropriate protective neoprene or polyethylene gloves to prevent skin exposure. Apron or clothing sufficient to protect skin. Clothing: Wear appropriate protective clothing to prevent skin exposure. Neoprene, PVC or polyethylene apron or clothing sufficient to protect skin. Respiratory Protection: Follow the OSHA respirator regulations found in 29CFR 1910.134. Always use a NIOSH-approved respirator when necessary. Wear appropriate OSHA/MSHA approved chemical cartridge respirator. If more than TLV, do not breathe vapour. Wear self-contained breathing apparatus. Ventilation: Use only in a chemical fume hood. Adequate ventilation to maintain vapour/dust below TLV. Other Protective Equipment: Make eye bath and emergency shower available.

SECTION 9 – Physical and Chemical Properties Physical State: Liquid Appearance: Colourless Odour: Pungent odour – acetic odour (vinegar-like) pH: 2.4 (1 M solution in water) Vapour Pressure: 1.52 kPa (11.4 mm Hg) @ 20 °C Vapour Density: 2.07 (air = 1) Evaporation Rate: 0.97 (n-Butyl acetate = 1) Viscosity-Dynamic: 1.22 mPa.s (100% w/w), 2.39 mPa.s (90% w/w) @ 20 °C. Boiling Point: 100% (w/w): 117.87 °C (244.2 °F)

Freezing/Melting Point: 100% (w/w): 16.635 °C (61.9 °F); 80.6% (w/w): -7.4 °C (18.7 °F) Decomposition Temperature: No information available. Solubility: Soluble in all proportions in water, ethanol, acetone, diethyl ether, glycerol and benzene. Specific Gravity/Density: 100% (w/w): 1.0495 @ 20 °C; 80% (w/w): 1.08 @ 15 °C Molecular Formula: C2H4O2 Molecular Weight: 60.0268

SECTION 10 – Stability and Reactivity Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Incompatible materials, ignition sources, sparks or flame, excess heat. Incompatibilities with Other Materials: Reacts with most common metals to produce hydrogen. Oxidizing agents, acids, alcohols, alkalies, amines, peroxides. Acetaldehyde, 2-aminoethanol, ammonium nitrate, bromine pentafluoride, chlorine trifluoride, chlorosulfonic acid, chromic acid, chronic anhydride + acetic anhydride, diallyl methyl carbinol + ozone, ethylene diamine, ethyleneimine, hydrogen peroxide, nitric acid, nitric acid + acetone, oleum, perchloric acid, permanganates, phosphorus isocyanate, phosphorus trichloride, potassium hydroxide, potassium-t-butoxide, sodium hydroxide, sodium peroxide, and xylene. See NFPA Fire Protection Guide for specifics. Hazardous Decomposition Products: Carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported. Reaction Product(s): Contact with incompatible materials may cause explosion or fire.

SECTION 11 – Toxicological Information RTECS: CAS# 64-19-7: AF1225000. LD50/LC50: CAS# 64-19-7: Inhalation, mouse: LC50 = 5620 ppm/1H. Oral, rat: LD50 = 3310 mg/kg. Skin, rabbit: LD50 = 1060 mg/kg. Carcinogenicity: CAS# 64-19-7: Not listed as carcinogen by ACGIH, IARC, NIOSH, NTP, OSHA, or CA Prop 65. Epidemiology: Standard Draize test: Skin, human – 50 mg/24H, mild reaction.

Teratogenicity: Effects of Newborn: behavioral, Oral-rat TDLo = 700 mg/kg. Reproductive: Fertility: male index, itt-rat TDLo = 400 mg/kg. Mutagenicity: There have been no positive reports once the effect of pH on culture media has been controlled. Neurotoxicity: No information available.

SECTION 12 – Ecological Information Ecotoxicity: Bluegill (fresh water) TLm = 75 ppm/96H. Goldfish (fresh water) TLm = 100 ppm/96H. Shrimp (aerated water) LC50 = 100-330 ppm/48H. Physical: No information available. Other: None.

Environmental: Substance spreads on soil surface and penetrates at rate dependent on soil type and water content. Substance readily degrades in water and shows little potential for bioaccumulation.


Page 4 of 6

SECTION 13 – Disposal Considerations Dispose of in a manner consistent with federal, provincial/state/territorial, and local regulations. RCRA D-Maximum Concentration of Contaminants: None of the components are on this list. RCRA D Series – Chronic Toxicity Reference Levels: None of the components are on this list. RCRA F Series Wastes: None of the components are on this list. RCRA P Series Wastes: None of the components are on this list. RCRA U Series Wastes: None of the components are on this list. RCRA Substances Banned from Land Disposal: None of the components are on this list.

SECTION 14 – Transport Information CANADIAN TRANSPORTATION OF DANGEROUS GOODS (TDG) SHIPPING INFORMATION

Shipping Name and Description: ACETIC ACID, GLACIAL; or ACETIC ACID SOLUTION, more than 80 per cent acid, by mass UN Number: UN2789 Class: 8, 3 Packing Group/Category: II Special Provisions: --- Marine Pollutant: --- Passenger Carrying Road/Railway Vehicle Index: 1 kg or L

NOTE: This information incorporates the Transportation of Dangerous Goods Regulations SOR/2001-286, effective October 14, 2009. US DEPARTMENT OF TRANSPORT (DOT) HAZARDOUS MATERIALS SHIPPING INFORMATION (49 CFR)

Shipping Name and Description: ACETIC ACID, GLACIAL or ACETIC ACID SOLUTION, with more than 80 percent acid, by mass Identification Number: UN2789 Hazard Class or Division: 8 Packing Group: II

NOTE: This information was taken from the US Code of Federal Regulations Title 49 - Transportation and is effective July 1, 2009. IATA (1 January – 31 December 2010)

Passenger and Cargo Aircraft

Cargo Aircraft Only

UN/ID No.

Proper Shipping Name / Description

Class or Div. (Sub Risk)

Hazard Label(s) PG Pkg

Inst Max Net Qty/Pkg

Pkg Inst

Max/Net Qty/Pkg

S.P. See 4.4

A B C D E I J K L M 2789 Acetic acid, glacial 8 (3) Corrosive &

Flamm. liquid II 809 1 L 813 30 L

NOTE: Consult IATA DG Regulations for the most recent information, abbreviations and reference marks.

SECTION 15 – Regulatory Information US OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION (OSHA) HAZARD COMMUNICATION STANDARD (29 CFR 1910.1200) OSHA Hazard Communication Evaluation: Meets criteria for hazardous material, as defined by 29 CFR 1910.1200.

US Federal TSCA: CAS# 64-19-7 is listed on the TSCA Inventory. Health and Safety Reporting List: None of the components are on this list. Chemical Test Rules: None of the components are on this list. TSCA Section 12b: None of the components are on this list. TSCA Significant New Use Rule (SNUR): None of the components are on this list. CERCLA Reportable Quantities (RQ): CAS# 64-19-7: final RQ = 5000 pounds (2270 kg). SARA Threshold Planning Quantities (TPQ): None of the components are on this list. SARA Hazard Categories: CAS# 64-19-7: Acute, chronic, flammable. SARA Section 313: None of the components are on this list.

Clean Air Act – Hazardous Air Pollutants (HAPs): None of the components are on this list. Clean Air Act – Class 1 Ozone Depletors: None of the components are on this list. Clean Air Act – Class 2 Ozone Depletors: None of the components are on this list. Clean Water Act – Hazardous Substances: CAS# 64-19-7 is listed as a Hazardous Substance under the CWA. Clean Water Act – Priority Pollutants: None of the components are on this list. Clean Water Act – Toxic Pollutants: None of the components are on this list. OSHA – Highly Hazardous: None of the components are on this list.

US State State Right to Know: Acetic acid can be found on the following state Right-to-Know lists: California, New Jersey (RTK# 0004), Florida, Pennsylvania, Minnesota, Massachusetts (100 lbs RQ).

California Prop 65: No information available. California No Significant Risk Level: No information available.

CANADIAN WORKPLACE HAZARDOUS MATERIALS INFORMATION SYSTEM (WHMIS) CCOHS WHMIS Classification: B3 - Flammable and combustible material - Combustible liquid. E - Corrosive material.


Page 5 of 6

WHMIS Health Effects Criteria Met by this Chemical: E - TDG class 8 - corrosive substance WHMIS Ingredient Disclosure List: Included for disclosure at 1% or greater.

Detailed WHMIS Classification According to Criteria: Class A - Compressed Gas: Does not meet criteria. Class B - Flammable and Combustible Material: Meets criteria for "Combustible liquid". Closed cup flash point: 39 °C. Class C - Oxidizing Material: Does not meet criteria. Class D - Poisonous and Infectious Material. Division 1 - Immediate and Serious Toxic Effects: Does not meet criteria.

Acute Lethality: Does not meet criteria. LC50 (mouse): 2810 ppm (4-hour exposure); LD50 (oral, rat): 3530 mg/kg; LD50 (dermal, guinea pig): 3300 mg/kg (28% solution) (unconfirmed).

Class D - Poisonous and Infectious Material. Division 2 - Other Toxic Effects: Does not meet criteria. See detailed evaluation below. Chronic Health Effects: Insufficient information. Carcinogenicity: Does not meet criteria. Not included in standard reference lists. Teratogenicity and Embryotoxicity: Insufficient information. Reproductive Toxicity: Insufficient information. Mutagenicity: Insufficient information. No in vivo studies located. Respiratory Tract Sensitization: Does not meet criteria. Not reported as human respiratory sensitizer. Skin Irritation: Corrosive materials are not also classified as irritants. Eye Irritation: Corrosive materials are not also classified as irritants. Skin Sensitization: Insufficient information. One case report of occupational skin sensitization to acetic acid.

Class E - Corrosive Material: Meets criteria. TDG Class 8; concentrated solutions are corrosive to eyes and skin. All concentrations of acetic acid are corrosive to type 1020 carbon steel up to 240 °C (115.6 °F). Very high concentrations are not corrosive to aluminum alloys (not specified). Water increases the corrosion rate of aluminum significantly. No information for type 7075-T6 aluminum was located.

Class F - Dangerously Reactive Material: Does not meet criteria. Canadian DSL/NDSL: CAS# 64-19-7 is listed on Canada’s DSL/NDSL List. EUROPEAN UNION (EU) CLASSIFICATION AND LABELLING INFORMATION

EU Index#: 607-002-00-6 EU Pictograms:

GHS05 GHS02

EU Signal Word: Danger EU Classification: Skin corrosion – Category 1A

Flammable liquid – Category 3 EU Hazard Statements: H226: Flammable liquid and vapour. H314: Causes severe skin burns and eye damage.

EU Precautionary Statements: P210: Keep away from heat/sparks/open flames/hot surfaces. – No smoking. P233: Keep container tightly closed. P240: Ground/bond container and receiving equipment. P241: Use explosion-proof electrical/ventilating/lighting/equipment. P242: Use only non-sparking tools. P243: Take precautionary measures against static discharge. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a

position comfortable for breathing. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P370+P378: In case of fire: Use dry chemical, carbon dioxide, or alcohol-resistant foam for extinction. Use water spray ONLY to cool fire-exposed containers or disperse vapours if they have not ignited. P310: Immediately call a POISON CENTER or doctor/physician. P321: Specific treatment (see P310). P363: Wash contaminated clothing before reuse. P403+P233: Store in a well-ventilated place. Keep cool. P405: Store locked up. P501: Dispose of contents/container according to federal, regional and local government requirements.

Exposure Limits CAS# 64-19-7: OEL-AUSTRALIA: TWA 10 ppm (25 mg/m3); STEL 15 ppm (37 mg/m3) OEL-BELGIUM: TWA 10 ppm (25 mg/m3); STEL 15 ppm (38 mg/m3) OEL-DENMARK: TWA 10 ppm (25 mg/m3) OEL-FINLAND: TWA 5 ppm (13 mg/m3); STEL 10 ppm (25 mg/m3) OEL-FRANCE: VLE 10 ppm (25 mg/m3) OEL-HUNGARY: TWA 25 mg/m3; STEL 25 mg/m3 OEL-JAPAN: TWA 10 ppm (25 mg/m3) OEL-KOREA: TWA 10 ppm (25 mg/m3); STEL 15 ppm (37 mg/m3) OEL-MEXICO: TWA 10 ppm (25 mg/m3); STEL 15 ppm (37 mg/m3) OEL-NETHERLANDS: MAC-TGG 25 mg/m3 OEL-NEW ZELAND: TWA 10 ppm (25 mg/m3); STEL 15 ppm (37 mg/m3)

OEL-NORWAY: TWA 10 ppm (25 mg/m3) OEL-THE PHILIPPINES: TWA 10 ppm (25 mg/m3) OEL-POLAND: TWA 5 mg/m3; STEL 35 mg/m3 OEL-RUSSIA: STEL 5 mg/m3; Skin OEL-SWEDEN: TWA 5 ppm (13 mg/m3); STEL 10 ppm (25 mg/m3) OEL-SWITZERLAND: MAC-W 10 ppm (25 mg/m3); KZG-W 20 ppm (50 mg/m3) OEL-THAILAND: TWA 10 ppm (25 mg/m3) OEL-TURKEY: TWA 10 ppm (25 mg/m3) OEL IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV OEL IN SINGAPORE, VIETNAM check ACGIH TLV


Page 6 of 6

SECTION 16 – Other Information The statements contained herein are offered for informational purposes only and are based upon technical data. Seastar Chemicals Inc believes them to be accurate but does not purport to be all-inclusive. The above-stated product is intended for use only by persons having the necessary technical skills and facilities for handling the product at their discretion and risk. Since conditions and manner of use are outside our control, we (Seastar Chemicals Inc) make no warranty of merchantability or any such warranty, express or implied with respect to information and we assume no liability resulting from the above product or its use. Users should make their own investigations to determine suitability of information and product for their particular purposes.

Material Safety Data SheetBacteriological Agar

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0

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1: Chemical Product and Company Identification

Product Name: Bacteriological Agar

Catalog Code: 30620001-1,30620001-2

CAS#: Not available.

RTECS: Not available.

TSCA: Not available.

CI#: Not available.

Synonym: Not available.

Chemical Name: Bacteriological Agar

Chemical Formula: Not available.

Contact information:

bioWORLD 4150 Tuller Rd Suite 228, Dublin, OH 43017, USA

For information, call: 614-792-8680 Fax Number: 614-792-8685 Order Online:www.bio-world.com

E-mail : [email protected]

In case of a chemical emergency, contact local hospital.

For non-emergency assistance,call: 1-800-860-9729

2: Composition and Information on Ingredients

Composition:

Name CAS# % by WeightBacteriological Agar Not available.

Toxicological Data on Ingredients:

Not available.

3: Hazards Identification

Potential Acute Health Effects: This product contains no hazardous constituents, or the concentration of all chemical constituents are below the regulatory threshold limits described by Occupational Safety Health Administration Hazard Communication Standard 29 CFR 1910.1200.

Potential Chronic Health Effects:

CARCINOGENIC EFFECTS: Not available.

000

1

MUTAGENIC EFFECTS: Not available.

TERATOGENIC EFFECTS: Not available.

DEVELOPMENTAL TOXICITY: Not available.

4: First Aid Measures

Eye Contact: Not available.

Skin Contact: Not available.

Serious Skin Contact: Not available.

Inhalation: Not available.

Serious Inhalation: Not available.

Ingestion: Not available.


5: Fire and Explosion Data

Flammability of the Product: Not available.

Auto-Ignition Temperature: Not available.

Flash Points: Not available.

Flammable Limits: Not available.

Product of Combustion: Not available

Fire Hazards in Presence of Various Substances: Not available

Explosion Hazards in Presence of Various Substances: Risks of explosion of the product under mechanical impact : Not availableRisks of explosion of the product under static discharge : Not available

Fire Fighting Media and Instructions:

SMALL FIRE: Dry chemical powder.

LARGE FIRE: CO2, extinguishing powder or water spray.

Special Remarks on Fire Hazards: Not available.

Special Remarks on Explosion Hazards: Not available.

6: Accidental Release Measures

Small Spill: Wipe up with damp sponge or mop.

Large Spill: Not available.

2

7: Handling and Storage

Precautions: No special measures required.

Storage: Keep container tightly closed. Suitable for any general chemical storage area.

8: Exposure Controls/Personal ProtectionEngineering Controls: Safety shower and eye bath.

Personal Protection: Respiratory Protection (Specify Type): None required where adequate ventilation conditions exist. Ventilation: Local Exhaust: 50 – 100 CFM Special Mechanical (General): N/A Other Protective Gloves: Proper disposable gloves Eye Protection:

Personal Protection in Case of a Large Spill: Not available.

Exposure Limits: Not available.

9: Physical and Chemical Properties

Physical State and Appearance: Not available.

Odor: Not available.

Taste: Not available.

Molecular Weight: Not available.

Color: Not available.

pH(1% soln/water): Not available.

Boiling Point: Not available.

Melting Point: Not available.

Critical Temperature: Not available.

Specific Gravity: Not available.

Vapour Pressure: Not available.

Vapor Density: Not available.


Odor Threshold: Not available.

Water/Oil Dist. Coeff: Not available.


Dispersion Properties: Not available.

Solubility: Not available.

10: Stability and Reactivity Data

Stability: Unstable.

3


Conditions of Instability: No decomposition if used according to specifications.

Incompatibility with various substances: Not available.

Corrosivity: Not available.

Special Remarks on Reactivity: Not available.


Polymerization: May Occur.

11:Toxicological Information

Routes of Entry: Not available.

Toxicity to Animals:

Not available.

Chronic Effects on Humans: Not available.

Other Toxic Effects on Humans: Not available.

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans: Not available.

Special Remarks on other Toxic Effects on Humans: Not available.

12: Ecological Information



Product of Biodegradation: Not available.

Toxicity of the Products of Biodegradation: Not available.


13: Disposal Considerations

Waste Disposal: Dispose in accordance with all applicable federal, state, and local environmental regulations.

14: Transport Information

DOT Classification: Not a DOT controlled material.

4

Identification: Not available.


15: Other Regulatory Information

Federal and State Regulations: Not available.

Other Regulations: Not available.


WHMIS(Canada): Not available.

DSCL(EEC): Not available.

HMIS(U.S.A):

Health Hazard: 0

Fire Hazard: 0

Reactivity: 0

Personal Protection:

National Fire Protection Association (U.S.A):

Health: 0

Flammability: 0

Reactivity: 0

Specific hazard:

Protective Equipment: Uniform, lab coat, or disposable lab wear.

16: Other Information



Created: 22/06/2006 3:12:43 PM

Last Updated: 03/01/2009 9:16:18 AM

Disclaimer

This product is offered by bioWORLD for research, laboratory or further manufacturing use. Not for human use or consumption.

The information above is believed to be accurate and represents the best information currently available to us. However,we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes.In no event shall Bio-World.com be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect,incidental,consequential or exemplary damages, howsoever arising,

5

even if Bio-World.com has been advised of the possibility of such damages.

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E

Material Safety Data SheetAgarose MSDS


Product Name: Agarose

Catalog Codes: SLA3607

CAS#: 9012-36-6

RTECS: QO6785000

TSCA: TSCA 8(b) inventory: Agarose

CI#: Not available.

Synonym:

Chemical Name: Not available.

Chemical Formula: (C6H10O5.C6H8O4)n







Agarose 9012-36-6 100

Toxicological Data on Ingredients: Not applicable.


Potential Acute Health Effects:Hazardous in case of ingestion. Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of inhalation.

Potential Chronic Health Effects:Hazardous in case of ingestion. Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of inhalation.CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available.


Eye Contact:Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Get medical attention if irritation occurs.

p. 2

Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.


Inhalation:If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medicalattention.


Ingestion:Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconsciousperson. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar,tie, belt or waistband.



Flammability of the Product: May be combustible at high temperature.





Fire Hazards in Presence of Various Substances: Not available.

Explosion Hazards in Presence of Various Substances:Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product inpresence of static discharge: Not available.

Fire Fighting Media and Instructions:SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet.




Small Spill:Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water onthe contaminated surface and dispose of according to local and regional authority requirements.

Large Spill:Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on thecontaminated surface and allow to evacuate through the sanitary system.


Precautions:Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under afume hood. Ground all equipment containing material. Do not breathe dust.

Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area.


p. 3

Engineering Controls:Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommendedexposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminantsbelow the exposure limit.

Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.Gloves.

Personal Protection in Case of a Large Spill:Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoidinhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling thisproduct.



Physical state and appearance: Solid.



Molecular Weight: Not available.




Melting Point: Decomposes.



Vapor Pressure: Not applicable.











Conditions of Instability: Not available.




p. 4




Routes of Entry: Ingestion.

Toxicity to Animals:LD50: Not available. LC50: Not available.


Other Toxic Effects on Humans:Hazardous in case of ingestion. Slightly hazardous in case of skin contact (irritant), of inhalation.








Toxicity of the Products of Biodegradation: The products of degradation are more toxic.



Waste Disposal:


DOT Classification: Not a DOT controlled material (United States).

Identification: Not applicable.

Special Provisions for Transport: Not applicable.


Federal and State Regulations: TSCA 8(b) inventory: Agarose



WHMIS (Canada): Not controlled under WHMIS (Canada).

DSCL (EEC):

p. 5

This product is not classified according to the EU regulations.

HMIS (U.S.A.):

Health Hazard: 1

Fire Hazard: 1

Reactivity: 0



Health: 1

Flammability: 1

Reactivity: 0

Specific hazard:

Protective Equipment:Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Safety glasses.




Created: 10/10/2005 08:13 PM

Last Updated: 05/21/2013 12:00 PM


/8Safety Data Sheet

acc. to OSHA HCSPrinting date 04/14/2016 Reviewed on 09/14/2015

42.2.4

1 Identification· Product identifier· Trade name: Bio-Safe™ Coomassie Stain· Catalog or product number: 1610786, 1610787, 1610786S, 1610787EDU, 9704607, 4307131, 4307045, 1610786EDU· Application of the substance / the mixture Laboratory chemicals

· Details of the supplier of the safety data sheet· Manufacturer/Supplier:Bio-Rad Laboratories, Life Science Group2000 Alfred Nobel DriveHercules, California 94547 (510)741-1000

· Information department:Technical services, customer [email protected]

· Emergency telephone number:1(800)424-9300 Use only in the event of a CHEMICAL EMERGENCY involving a SPILL, LEAK, FIRE, EXPLOSION orACCIDENT.510-741-1000

* 2 Hazard(s) identification· Classification of the substance or mixtureThe product is not classified according to the Globally Harmonized System (GHS).

· Label elements· GHS label elements Void· Hazard pictograms Void· Signal word Void· Hazard statements Void· Additional information: Contact with acids may cause release of toxic gases· Other hazards· Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.

* 3 Composition/information on ingredients· Chemical characterization: Mixtures· Description: Mixture of the substances listed below with non-hazardous additions.· Listing of dangerous and non-hazardous components:7664-38-2 phosphoric acid Skin Corr. 1B, H314 2.5-5%

67-56-1 methanol Flam. Liq. 2, H225Acute Tox. 3, H301; Acute Tox. 3, H311; Acute Tox. 3, H331STOT SE 1, H370

0.1-1.0%

7732-18-5 water 50-100%· Additional information For the wording of the listed risk phrases refer to section 15.

US

(Contd. on page 2)

/8Safety Data Sheet


Trade name: Bio-Safe™ Coomassie Stain

(Contd. of page 1)

42.2.4

* 4 First-aid measures· Description of first aid measures· General information No special measures required.· After inhalation Supply fresh air; consult doctor in case of complaints.· After skin contact Generally the product does not irritate the skin.· After eye contact Rinse opened eye for several minutes under running water.· After swallowing Induce vomiting and call for medical help.· Information for doctor· Most important symptoms and effects, both acute and delayed No further relevant information available.· Indication of any immediate medical attention and special treatment needed No further relevant information available.

* 5 Fire-fighting measures· Extinguishing media· Suitable extinguishing agentsCO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam.

· Special hazards arising from the substance or mixture No further relevant information available.· Advice for firefighters· Protective equipment: No special measures required.

* 6 Accidental release measures· Personal precautions, protective equipment and emergency procedures Wear protective clothing.· Environmental precautions:Dilute with plenty of water.Do not allow to enter sewers/ surface or ground water.

· Methods and material for containment and cleaning up:Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).

· Reference to other sectionsNo dangerous substances are released.See Section 7 for information on safe handlingSee Section 8 for information on personal protection equipment.See Section 13 for disposal information.

* 7 Handling and storage· Handling· Precautions for safe handling No special measures required.· Information about protection against explosions and fires: No special measures required.

· Conditions for safe storage, including any incompatibilities· Storage· Requirements to be met by storerooms and receptacles: According to product specification· Information about storage in one common storage facility: Not required.· Further information about storage conditions: None.

(Contd. on page 3) US

/8Safety Data Sheet



(Contd. of page 2)

42.2.4

· Specific end use(s) No further relevant information available.

* 8 Exposure controls/personal protection· Additional information about design of technical systems: No further data; see item 7.

· Control parameters· Components with limit values that require monitoring at the workplace:7664-38-2 phosphoric acidPEL Long-term value: 1 mg/m³REL Short-term value: 3 mg/m³

Long-term value: 1 mg/m³TLV Short-term value: 3 mg/m³

Long-term value: 1 mg/m³67-56-1 methanolPEL Long-term value: 260 mg/m³, 200 ppmREL Short-term value: 325 mg/m³, 250 ppm

Long-term value: 260 mg/m³, 200 ppmSkin

TLV Short-term value: 328 mg/m³, 250 ppmLong-term value: 262 mg/m³, 200 ppmSkin; BEI

64-17-5 ethanolPEL Long-term value: 1900 mg/m³, 1000 ppmREL Long-term value: 1900 mg/m³, 1000 ppmTLV Short-term value: 1880 mg/m³, 1000 ppm

· Ingredients with biological limit values:67-56-1 methanolBEI 15 mg/L

Medium: urineTime: end of shiftParameter: Methanol (background, nonspecific)

· Additional information: The lists that were valid during the creation were used as basis.

· Exposure controls· Personal protective equipment· General protective and hygienic measures The usual precautionary measures for handling chemicals should be followed.· Breathing equipment: Not required.· Protection of hands: Protective gloves.· Material of gloves Synthetic gloves· Penetration time of glove materialThe exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.

· Eye protection: Safety glasses US

(Contd. on page 4)

/8Safety Data Sheet



(Contd. of page 3)

42.2.4

* 9 Physical and chemical properties· Information on basic physical and chemical properties· General Information· Appearance:

Form: LiquidColor: Blue

· Odor: Acrid· Odor threshold: Not determined.

· pH-value: Not determined.

· Change in conditionMelting point/Melting range: undeterminedBoiling point/Boiling range: undetermined

· Flash point: Not applicable

· Flammability (solid, gaseous) Not applicable.

· Ignition temperature:Decomposition temperature: Not determined.

· Auto igniting: Product is not selfigniting.

· Danger of explosion: Product does not present an explosion hazard.

· Explosion limits:Lower: Not determined.Upper: Not determined.

· Vapor pressure at 20 °C: 23 hPa

· Density: Not determined· Relative density Not determined.· Vapor density Not determined.· Evaporation rate Not determined.

· Solubility in / Miscibility withWater: Fully miscible

· Partition coefficient (n-octanol/water): Not determined.

· Viscosity:dynamic: Not determined.kinematic: Not determined.

· Solvent content:Organic solvents: 1.1 %Water: 93.9 %

· Other information No further relevant information available.

* 10 Stability and reactivity· Reactivity No further relevant information available.


/8Safety Data Sheet



(Contd. of page 4)

42.2.4

· Chemical stability· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.· Possibility of hazardous reactions No dangerous reactions known· Conditions to avoid No further relevant information available.· Incompatible materials: No further relevant information available.· Hazardous decomposition products: No dangerous decomposition products known

* 11 Toxicological information· Information on toxicological effects· Acute toxicity:· LD/LC50 values for hazardous components per OSHA criteria:67-56-1 methanolOral LD50 5628 mg/kg (rat)Dermal LD50 20000 mg/kg (rat)

· Primary irritant effect:· on the skin: No irritant effect.· on the eye: No irritant effect.· Sensitization: No sensitizing effects known.· Additional toxicological information:The product is not subject to classification according to the calculation method of the General EU Classification Guidelinesfor Preparations as issued in the latest version:When used and handled according to specifications, the product does not have any harmful effects according to ourexperience and the information provided to us.

· Carcinogenic categories· IARC (International Agency for Research on Cancer)64-17-5 ethanol 1

· NTP (National Toxicology Program)None of the ingredients is listed.

· OSHA-Ca (Occupational Safety & Health Administration)None of the ingredients is listed.

· Target organs: Not applicable.

* 12 Ecological information· Toxicity· Aquatic toxicity: No further relevant information available.· Persistence and degradability No further relevant information available.· Behavior in environmental systems:· Bioaccumulative potential No further relevant information available.· Mobility in soil No further relevant information available.· Additional ecological information:· General notes:Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water.Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.


/8Safety Data Sheet



(Contd. of page 5)

42.2.4

· Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.· Other adverse effects No further relevant information available.

* 13 Disposal considerations· Waste treatment methods· RecommendationHand over to hazardous waste disposers.Must not be disposed of together with household garbage. Do not allow product to reach sewage system.

· Uncleaned packagings:· Recommendation: Disposal must be made according to official regulations.· Recommended cleansing agent: Water, if necessary with cleansing agents.

* 14 Transport information· UN-Number· DOT, ADR, ADN, IMDG, IATA Void

· UN proper shipping name· DOT, ADR, ADN, IMDG, IATA Void

· Transport hazard class(es)· DOT, ADR, ADN, IMDG, IATA· Class Void

· Packing group· DOT, ADR, IMDG, IATA Void

· Environmental hazards:· Marine pollutant: No

· Special precautions for user Not applicable.

· Transport in bulk according to Annex II of MARPOL73/78and the IBC Code Not applicable.

· Transport/Additional information: Not dangerous according to the above specifications.

· UN "Model Regulation": Void

* 15 Regulatory information· Safety, health and environmental regulations/legislation specific for the substance or mixture· SARA (Superfund Amendents and Reauthorization Act of 1986 - USA)· Section 302/304 (40CFR355.30 / 40CFR355.40):None of the ingredients is listed.


/8Safety Data Sheet



(Contd. of page 6)

42.2.4

· Section 313 (40CFR372.65):67-56-1 methanol

· TSCA (Toxic Substances Control Act):All ingredients are listed.

· California Proposition 65:· Developmental Toxicity67-56-1 methanol64-17-5 ethanol

· Carcinogenic categories· EPA (Environmental Protection Agency)None of the ingredients is listed.

· TLV (Threshold Limit Value established by ACGIH)64-17-5 ethanol A3

· MAK (German Maximum Workplace Concentration)64-17-5 ethanol 5

· NIOSH-Ca (National Institute for Occupational Safety and Health)None of the ingredients is listed.

· National regulations· Technical instructions (air):

Class Share in %I 0.1-1.0

NK 0.01-0.1

· Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water.· Chemical safety assessment: A Chemical Safety Assessment has not been carried out.

16 Other informationThis information is based on our present knowledge. However, this shall not constitute a guarantee for any specific productfeatures and shall not establish a legally valid contractual relationship.

· Department issuing SDS: Environmental Health and Safety.· Contact:Life Science Group, Environmental Health and Safety, 2000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 741-1000

Diagnostic Group, Environmental Health and Safety, 4000 Alfred Nobel Drive, Hercules, California, 94547: 1(510) 724-7000· Date of preparation / last revision 04/14/2016 / -· Abbreviations and acronyms:

ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage ofDangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsDOT: US Department of TransportationIATA: International Air Transport AssociationACGIH: American Conference of Governmental Industrial HygienistsEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical Substances


/8Safety Data Sheet



(Contd. of page 7)

42.2.4

CAS: Chemical Abstracts Service (division of the American Chemical Society)LC50: Lethal concentration, 50 percentLD50: Lethal dose, 50 percentPBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very BioaccumulativeNIOSH: National Institute for Occupational SafetyOSHA: Occupational Safety & HealthTLV: Threshold Limit ValuePEL: Permissible Exposure LimitREL: Recommended Exposure LimitBEI: Biological Exposure LimitFlam. Liq. 2: Flammable liquids, Hazard Category 2Acute Tox. 3: Acute toxicity, Hazard Category 3Skin Corr. 1B: Skin corrosion/irritation, Hazard Category 1BSTOT SE 1: Specific target organ toxicity - Single exposure, Hazard Category 1

· * Data compared to the previous version altered. US

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Material Safety Data SheetBuffer Solution, pH 4.01/CLEAR MSDS


Product Name: Buffer Solution, pH 4.01/CLEAR

Catalog Codes: SLB2821, SLB4321

CAS#: Mixture.


TSCA: TSCA 8(b) inventory: Potassium biphthalate;Hydrochloric acid; Methyl paraben; Propyl paraben; Water


Synonym:

Chemical Name: Not applicable.








Potassium biphthalate 877-24-7 1.02

Hydrogen chloride 7647-01-0 0.000192

Water 7732-18-5 99

Methyl paraben 99-76-3 0.01

Propyl paraben 94-13-3 0.0025

Toxicological Data on Ingredients: Potassium biphthalate LD50: Not available. LC50: Not available.


Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion. Non-hazardous in case of inhalation.

Potential Chronic Health Effects: Non-corrosive for skin. Non-sensitizer for skin. Non-permeator by skin. CARCINOGENICEFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available. The substance is toxic to lungs, mucous membranes. Repeated or prolongedexposure to the substance can produce target organs damage.

p. 2


Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for atleast 15 minutes. Cold water may be used. Get medical attention if irritation occurs.

Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.


Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Getmedical attention.


Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to anunconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing suchas a collar, tie, belt or waistband.







Products of Combustion: These products are carbon oxides (CO, CO2). Some metallic oxides.

Fire Hazards in Presence of Various Substances: Slightly flammable to flammable in presence of open flames and sparks.Non-flammable in presence of shocks, of heat, of oxidizing materials, of reducing materials, of combustible materials, oforganic materials, of metals, of acids, of alkalis.

Explosion Hazards in Presence of Various Substances: Risks of explosion of the product in presence of mechanicalimpact: Not available. Risks of explosion of the product in presence of static discharge: Not available.

Fire Fighting Media and Instructions: SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog orfoam. Do not use water jet.




Small Spill: Absorb with an inert material and put the spilled material in an appropriate waste disposal. If necessary:Neutralize the residue with a dilute solution of sodium carbonate.

Large Spill: Absorb with an inert material and put the spilled material in an appropriate waste disposal. Neutralize the residuewith a dilute solution of sodium carbonate. Finish cleaning by spreading water on the contaminated surface and allow toevacuate through the sanitary system.


Precautions: Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate theresidue under a fume hood. Ground all equipment containing material. Do not breathe gas/fumes/ vapor/spray.


p. 3


Engineering Controls: Provide exhaust ventilation or other engineering controls to keep the airborne concentrations ofvapors below their respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location.

Personal Protection: Safety glasses. Lab coat.

Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing mightnot be sufficient; consult a specialist BEFORE handling this product.




Odor: Odorless.




pH (1% soln/water): Acidic.

Boiling Point: The lowest known value is 100°C (212°F) (Water).



Specific Gravity: Weighted average: 1 (Water = 1)

Vapor Pressure: The highest known value is 2.3 kPa (@ 20°C) (Water).

Vapor Density: The highest known value is 0.62 (Air = 1) (Water).






Solubility: Easily soluble in cold water, methanol. Soluble in diethyl ether, acetone. Very slightly soluble in hot water.






Corrosivity: Non-corrosive in presence of glass, of stainless steel(304), of stainless steel(316).

Special Remarks on Reactivity: Reacts violently with water especially when water is added to the product. (Hydrogenchloride)


p. 4

Polymerization: Not available.



Toxicity to Animals: LD50: Not available. LC50: Not available.


Other Toxic Effects on Humans: Slightly hazardous in case of skin contact (irritant), of ingestion. Non-hazardous in case ofinhalation.



Special Remarks on other Toxic Effects on Humans: Material is extremely destructive to tissue of the mucous membranesand upper respiratory tract. (Hydrogen chloride)




Products of Biodegradation: Possibly hazardous short term degradation products are not likely. However, long termdegradation products may arise.


Special Remarks on the Products of Biodegradation: Decomposes and burns to form smoke, carbon monoxide andcarbon dioxide. Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source ia s potentialdust explosion hazard. (Methyl paraben)


Waste Disposal:






Federal and State Regulations: Pennsylvania RTK: Hydrochloric acid Massachusetts RTK: Hydrochloric acid TSCA8(b) inventory: Potassium biphthalate; Hydrochloric acid; Methyl paraben; Propyl paraben; Water SARA 302/304/311/312extremely hazardous substances: Hydrochloric acid CERCLA: Hazardous substances.: Hydrochloric acid;



WHMIS (Canada): CLASS D-2A: Material causing other toxic effects (VERY TOXIC).

p. 5

DSCL (EEC): This product is not classified according to the EU regulations.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 0

Reactivity: 0

Personal Protection: a


Health: 2

Flammability: 0

Reactivity: 0

Specific hazard:

Protective Equipment: Not applicable. Lab coat. Wear appropriate respirator when ventilation is inadequate. Safety glasses.




Created: 10/10/2005 12:54 AM

Last Updated: 05/21/2013 12:00 PM


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Catalog Codes: SLB3964

CAS#: Mixture.


TSCA: TSCA 8(b) inventory: Potassium phosphatemonobasic; Sodium hydroxide; Water

CI#: Not available.

Synonym:









Potassium phosphate monobasic 7778-77-0 0.682

Sodium hydroxide 1310-73-2 0.068

Water 7732-18-5 99.3

Toxicological Data on Ingredients: Potassium phosphate monobasic LD50: Not available. LC50: Not available.


Potential Acute Health Effects: Slightly hazardous in case of skin contact (corrosive, irritant), of eye contact (irritant), ofingestion, of inhalation.

Potential Chronic Health Effects: Non-corrosive for skin. Non-irritant for skin. Non-sensitizer for skin. Non-permeator byskin. Non-irritating to the eyes. Non-hazardous in case of ingestion. Non-hazardous in case of inhalation. CARCINOGENICEFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available.


p. 2

Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for atleast 15 minutes. Cold water may be used. Get medical attention if irritation occurs.

Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.Cold water may be used.


Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Getmedical attention.


Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to anunconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing suchas a collar, tie, belt or waistband.



Flammability of the Product: Non-flammable.

Auto-Ignition Temperature: Not applicable.

Flash Points: Not applicable.

Flammable Limits: Not applicable.

Products of Combustion: Not available.

Fire Hazards in Presence of Various Substances: Not applicable.

Explosion Hazards in Presence of Various Substances: Risks of explosion of the product in presence of mechanicalimpact: Not available. Risks of explosion of the product in presence of static discharge: Not available.

Fire Fighting Media and Instructions: Not applicable.




Small Spill: Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposalcontainer. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regionalauthority requirements.

Large Spill: Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning byspreading water on the contaminated surface and allow to evacuate through the sanitary system.


Precautions: Keep container dry. Do not breathe gas/fumes/ vapor/spray. Avoid contact with skin. Never add water to thisproduct. Wear suitable protective clothing. If you feel unwell, seek medical attention and show the label when possible.



p. 3

Engineering Controls: Provide exhaust ventilation or other engineering controls to keep the airborne concentrations ofvapors below their respective threshold limit value.

Personal Protection: Safety glasses. Lab coat. Gloves.

Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing mightnot be sufficient; consult a specialist BEFORE handling this product.




Odor: Odorless.





Boiling Point: 100°C (212°F)



Specific Gravity: The only known value is 1 (Water = 1) (Water).







Dispersion Properties: See solubility in water.

Solubility: Easily soluble in cold water, hot water.










p. 4





Other Toxic Effects on Humans: Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.











Waste Disposal:






Federal and State Regulations: Pennsylvania RTK: Sodium hydroxide Massachusetts RTK: Sodium hydroxide TSCA 8(b)inventory: Potassium phosphate monobasic; Sodium hydroxide; Water




DSCL (EEC): This product is not classified according to the EU regulations.

HMIS (U.S.A.):

Health Hazard: 1

Fire Hazard: 0

Reactivity: 0

p. 5

Personal Protection: b


Health: 1

Flammability: 0

Reactivity: 0

Specific hazard:

Protective Equipment: Gloves. Lab coat. Not applicable. Safety glasses.




Created: 10/10/2005 12:55 AM

Last Updated: 05/21/2013 12:00 PM


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Catalog Codes: SLB2770

CAS#: Mixture.


TSCA: TSCA 8(b) inventory: Sodium borate; Sodiumhydroxide; Water

CI#: Not available.

Synonym:









Sodium borate 1303-96-4 0.475

Sodium hydroxide 1310-73-2 0.0732

Water 7732-18-5 99.5

Toxicological Data on Ingredients: Sodium borate: ORAL (LD50): Acute: 2660 mg/kg [Rat.].


Potential Acute Health Effects: Slightly hazardous in case of skin contact (corrosive, irritant), of eye contact (irritant), ofingestion.

Potential Chronic Health Effects:Non-corrosive for skin. Non-irritant for skin. Non-sensitizer for skin. Non-permeator by skin. Non-irritating to the eyes.Non-hazardous in case of ingestion. Non-hazardous in case of inhalation. CARCINOGENIC EFFECTS: Not available.MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Notavailable.


p. 2

Eye Contact:Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Cold water may be used. Get medical attention if irritation occurs.

Skin Contact:Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold watermay be used.


















Small Spill:Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container.Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authorityrequirements.

Large Spill:Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by spreading wateron the contaminated surface and allow to evacuate through the sanitary system. Be careful that the product is not present at aconcentration level above TLV. Check TLV on the MSDS and with local authorities.


p. 3

Precautions:Keep container dry. Do not breathe gas/fumes/ vapor/spray. Avoid contact with skin. Never add water to this product. Wearsuitable protective clothing. If you feel unwell, seek medical attention and show the label when possible.



Engineering Controls:Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respectivethreshold limit value.

Personal Protection: Safety glasses. Lab coat. Gloves.

Personal Protection in Case of a Large Spill:Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a specialist BEFOREhandling this product.

Exposure Limits:Sodium borate TWA: 0.31 TWA: 5 from ACGIH (TLV) [United States] [1995] Consult local authorities for acceptable exposurelimits.











Specific Gravity: The only known value is 1 (Water = 1) (Water).








Solubility:Easily soluble in cold water. Soluble in hot water. Insoluble in methanol.


p. 4





Corrosivity:Corrosive in presence of aluminum. Non-corrosive in presence of glass.



Polymerization: Not available.





Other Toxic Effects on Humans: Slightly hazardous in case of skin contact (irritant), of ingestion.



Special Remarks on other Toxic Effects on Humans: Ingestion of 5-10 grams has produced severe vomiting, diarrhea,shock and death. (Sodium borate)








Waste Disposal:





p. 5


Federal and State Regulations:Pennsylvania RTK: Sodium borate; Sodium hydroxide Massachusetts RTK: Sodium borate; Sodium hydroxide TSCA 8(b)inventory: Sodium borate; Sodium hydroxide; Water




DSCL (EEC):This product is not classified according to the EU regulations.

HMIS (U.S.A.):

Health Hazard: 1

Fire Hazard: 0

Reactivity: 0

Personal Protection: b


Health: 1

Flammability: 0

Reactivity: 0

Specific hazard:

Protective Equipment:Gloves. Lab coat. Not applicable. Safety glasses.




Created: 10/10/2005 12:55 AM

Last Updated: 05/21/2013 12:00 PM


Material Safety Data SheetCasamino Acids

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Product Name: Casamino Acids

Catalog Code: 40300048-1, 40300048-2

CAS#: 65072−00−6

RTECS: Not listed.

TSCA: TSCA 8(b) inventory : Casamino acids.

CI#: Not available.

Synonym: Caseinate; Casein; Casamino acids is an acid−hydrolyzed casein used in culture media.

Chemical Name: Casamino Acids

Chemical Formula: Mixture.








Composition:

Name CAS# % by WeightCasamino Acids 65072−00−6 -


Not available.


Potential Acute Health Effects: May cause mechanical eye and skin irritation. May cause respiratory tract irritation. This is expected to be a low hazard for usual industrial handling.




010

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4: First Aid MeasuresEye Contact: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Skin Contact: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.


Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.


Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2−4 cupfuls of milk or water. Get medical aid.







Product of Combustion: Carbon monoxide, oxides of nitrogen, carbon dioxide.

Fire Hazards in Presence of Various Substances: This material in sufficient quantity and reduced particle size is capable of creating a dust explosion.

Explosion Hazards in Presence of Various Substances: Not available.



LARGE FIRE: In case of fire, use water, dry chemical, chemical foam, or alcohol−resistant foam.



6: Accidental Release MeasuresSmall Spill: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation.Large Spill: Not available.

2

7: Handling and StoragePrecautions: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.Storage: Store in a tightly closed container. Keep from contact with oxidizing materials. Storage under a nitrogen blanket has been recommended. Do not exceed 30°C (86°F).

8: Exposure Controls/Personal ProtectionEngineering Controls: Safety shower and eye bath. Mechanical exhaust required.

Personal Protection: Respiratory : Government approved respirator.Hand: Chemical resistant gloves.Eye: Safety glasses.

Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Boots. Dust respirator. Gloves.



Physical State and Appearance: Tan powder.

Odor: Characteristic odor.


Molecular Weight: Mixture.


pH(1% soln/water): Not available.





Vapour Pressure: Negligible.







Solubility: Soluble.


Stability: Stable.

3


Conditions of Instability: Dust generation, moisture, excess heat.

Incompatibility with various substances: Strong oxidizers.






Routes of Entry: Eye contact. Skin contact. Ingestion. Inhalation.


Not available.


Other Toxic Effects on Humans: Eye: Dust may cause mechanical irritation.Skin: May cause skin irritation. Low hazard for usual industrial handling.Ingestion: Ingestion of large amounts may cause gastrointestinal irritation.Inhalation: May cause respiratory tract irritation. Low hazard for usual industrial handling.











Waste Disposal: Waste must be disposed of according to federal,state and local environmental regulations.


4





Federal and State Regulations: TSCA 8(b) inventory : Casamino acids.

Other Regulations: EU ADDITIONAL CLASSIFICATION Hazard Symbols: Not available.Risk Phrases:Safety Phrases:S 24/25 Avoid contact with skin and eyes.


WHMIS(Canada): Not controlled by WHMIS.


HMIS(U.S.A):

Health Hazard: 0

Fire Hazard: 1

Reactivity: 0



Health: 0

Flammability: 1

Reactivity: 0

Specific hazard:

Protective Equipment: Gloves. Lab coat. Dust respirator. Safety goggles.




Created: 19/07/2006 11:58:41 AM

Last Updated: 11/12/2008 2:48:39 PM

Disclaimer


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The information above is believed to be accurate and represents the best information currently available to us. However,we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes.In no event shall Bio-World.com be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect,incidental,consequential or exemplary damages, howsoever arising, even if Bio-World.com has been advised of the possibility of such damages.

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Material Safety Data SheetDextrose anhydrous MSDS


Product Name: Dextrose anhydrous

Catalog Codes: SLD3880, SLD4483

CAS#: 50-99-7

RTECS: LZ6600000

TSCA: TSCA 8(b) inventory: Dextrose anhydrous

CI#: Not available.

Synonym: D-Glucose


Chemical Formula: C6H12O6







Dextrose anhydrous 50-99-7 100



Potential Acute Health Effects: Slightly hazardous in case of eye contact (irritant), of ingestion, of inhalation.

Potential Chronic Health Effects:CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure is not known to aggravate medical condition.


Eye Contact: Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may beused.

Skin Contact: No known effect on skin contact, rinse with water for a few minutes.


p. 2

Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical attention.


Ingestion:Do not induce vomiting. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, performmouth-to-mouth resuscitation. Seek immediate medical attention.















Large Spill:Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on thecontaminated surface and allow to evacuate through the sanitary system. Be careful that the product is not present at aconcentration level above TLV. Check TLV on the MSDS and with local authorities.


Precautions:Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under afume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. If ingested, seek medical adviceimmediately and show the container or the label.

Storage:Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly closed. Keep in acool, well-ventilated place. Combustible materials should be stored away from extreme heat and away from strong oxidizingagents.


p. 3




Exposure Limits:TWA: 300 (ppm) Consult local authorities for acceptable exposure limits.








Boiling Point: Decomposes.

Melting Point: 146°C (294.8°F)










Solubility: Easily soluble in cold water.








p. 4


Polymerization: No.



Toxicity to Animals: Acute oral toxicity (LD50): 25800 mg/kg [Rat].


Other Toxic Effects on Humans: Slightly hazardous in case of ingestion, of inhalation.


Special Remarks on Chronic Effects on Humans: Passes through the placental barrier in human.









Waste Disposal:






Federal and State Regulations: TSCA 8(b) inventory: Dextrose anhydrous

Other Regulations: Not available..




HMIS (U.S.A.):

p. 5

Health Hazard: 1

Fire Hazard: 1

Reactivity: 0



Health: 1

Flammability: 1

Reactivity: 0

Specific hazard:

Protective Equipment:Not applicable. Lab coat. Not applicable. Safety glasses.




Created: 10/11/2005 11:46 AM

Last Updated: 05/21/2013 12:00 PM


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Material Safety Data SheetDimethyl sulfoxide MSDS


Product Name: Dimethyl sulfoxide

Catalog Codes: SLD3139, SLD1015

CAS#: 67-68-5

RTECS: PV6210000

TSCA: TSCA 8(b) inventory: Dimethyl sulfoxide


Synonym: Methyl Sulfoxide; DMSO

Chemical Name: Dimethyl Sulfoxide

Chemical Formula: (CH3)2SO







Dimethyl sulfoxide 67-68-5 100

Toxicological Data on Ingredients: Dimethyl sulfoxide: ORAL (LD50): Acute: 14500 mg/kg [Rat]. 7920 mg/kg [Mouse].DERMAL (LD50): Acute: 40000 mg/kg [Rat].


Potential Acute Health Effects:Slightly hazardous in case of inhalation (lung irritant). Slightly hazardous in case of skin contact (irritant, permeator), of eyecontact (irritant), of ingestion, .

Potential Chronic Health Effects:Slightly hazardous in case of skin contact (irritant, sensitizer, permeator), of ingestion. CARCINOGENIC EFFECTS:Not available. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast.TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available. The substance may be toxic toblood, kidneys, liver, mucous membranes, skin, eyes. Repeated or prolonged exposure to the substance can produce targetorgans damage.


p. 2

Eye Contact:Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelidsopen. Cold water may be used. Get medical attention if irritation occurs.








Flammability of the Product: Combustible.

Auto-Ignition Temperature: 215°C (419°F)

Flash Points: CLOSED CUP: 89°C (192.2°F). OPEN CUP: 95°C (203°F).

Flammable Limits: LOWER: 2.6% UPPER: 28.5% (Lewis), 42% (NFPA)

Products of Combustion: These products are carbon oxides (CO, CO2), sulfur oxides (SO2, SO3...).

Fire Hazards in Presence of Various Substances:Flammable in presence of open flames and sparks, of heat. Non-flammable in presence of shocks.



Special Remarks on Fire Hazards:When heated above its boiling point, dimethyl sulfoxide degrades giving off formaldehyde, methyl mercaptan, and sulfurdioxide




Large Spill:Combustible material. Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. If the product is inits solid form: Use a shovel to put the material into a convenient waste disposal container. If the product is in its liquid form:Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by spreading wateron the contaminated surface and allow to evacuate through the sanitary system.

p. 3


Precautions:Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Do notbreathe gas/fumes/ vapor/spray. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratoryequipment. If ingested, seek medical advice immediately and show the container or the label. Keep away from incompatiblessuch as oxidizing agents.

Storage:Keep container in a cool, well-ventilated area. Keep container tightly closed and sealed until ready for use. Avoid all possiblesources of ignition (spark or flame). Hygroscopic. Sensitive to light. Store in light-resistant containers.



Personal Protection:Safety glasses. Synthetic apron. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves(impervious).





Odor: Sulfurous. (Slight.)

Taste: Bitter with sweet after-taste (Slight.)




Boiling Point: 189°C (372.2°F)

Melting Point: 18.45°C (65.2°F)







Water/Oil Dist. Coeff.: The product is more soluble in water; log(oil/water) = -2


Dispersion Properties: See solubility in water, diethyl ether, acetone.

p. 4

Solubility:Soluble in cold water, hot water, diethyl ether, acetone. Soluble in chloroform, ethanol, and benzene.




Conditions of Instability: Heat, ignition sources, flames, incompatibles

Incompatibility with various substances: Reactive with oxidizing agents, reducing agents, acids, alkalis.


Special Remarks on Reactivity:Hygroscopic. It has a strong water affinity, and if left exposed it will become rapidly diluted. Incompatible with strong oxidants,arylhalides, bromobenzoyl acetanilide, magnesium perchlorate, perchloric acid, and sodium hydroxide, alkali metals,hydrobromic acid, acidic solutions of alkali bromides, organic and inorganic acid chlorides, acid halides, cyanuric chloride,silver fluoride, methyl bromide, sodium hydride, periodic acid, diborane, iodine pentafluoride, silicon tetrachloride, phosphoroushalides (phosphorous trichloride), trichloroacetic acid + copper wool, phosphorous trioxide, thionyl chloride, plastics




Routes of Entry: Absorbed through skin. Eye contact. Inhalation.

Toxicity to Animals:Acute oral toxicity (LD50): 7920 mg/kg [Mouse]. Acute dermal toxicity (LD50): 40000 mg/kg [Rat].

Chronic Effects on Humans:MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast. May cause damage tothe following organs: blood, kidneys, liver, mucous membranes, skin, eyes.

Other Toxic Effects on Humans:Slightly hazardous in case of inhalation (lung irritant). Slightly hazardous in case of skin contact (irritant, permeator), ofingestion, .


Special Remarks on Chronic Effects on Humans:May cause adverse reproductive effects (female fertility and fetotoxicity - post implantation mortality) and birth defects basedon animal data. May cause cancer (tumorigenic) based on animal data. May affect genetic material (mutagenic).

Special Remarks on other Toxic Effects on Humans:Acute Potential Health Effects: Skin: Causes skin irritation. May cause urticaria(hives), skin rashes, and dermatitis. DimethylSulfoxide is readily absorbed through skin and may carry other dissolved chemicals into the body. An unusual garlic-onion-oyster odor may develop on breath and body/skin. Absorption through skin may also cause diarrhea, and affectrespiration(dyspnea, cyanosis), blood, behavior (fatigue, dizziness, sedation, headaches), vision (transient photophobia,and disturbances of color vision), urinary system (hematuria). Eyes: Causes eye irritation. May cause blurred vision,corneal opacity, chemical conjunctivitis. Inhalation: Causes respiratory tract irritation. Symptoms from exposure to highvapor concentrations may include coughing, shortness of breath, headache, dizziness and sedation. Ingestion: Causesgastrointestinal tract irritation, and an usual garlic-onion-oyster may develop on breath, and body/skin. May affect behavior/central nervous system, respiration (dyspnea). Symptoms may include nausea, vomiting, and diarrhea, abdominal pain,drowsiness, confusion, lethargy, agitation, disorientation, tremor, muscle weakness, chills, chest pains. May also affect liver(elevated liver enzymes, jaundice), cardiovascular system, and urinary system (hematuria, hemoglobinuria, renal tubularinjury), eyes (transient photophobia and disturbances of color vision, conjunctive irritation) Chronic Potential Health Effects:Skin: Chronic absorption may cause effects similar to that of acute skin absorption. Chronic skin contact may cause scaling

p. 5

dermatitis. Ingestion: Repeated oral doses may affect the kidneys (hematuria), blood (normocytic anemia, changes in redblood cell count), and metabolism (weight loss/anorexia), liver (jaundice).














Federal and State Regulations: TSCA 8(b) inventory: Dimethyl sulfoxide

Other Regulations:OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). EINECS: This product is on theEuropean Inventory of Existing Commercial Chemical Substances. National Inventory Lists of China, Japan, Korea, andPhilippines.


WHMIS (Canada):CLASS B-3: Combustible liquid with a flash point between 37.8°C (100°F) and 93.3°C (200°F).

DSCL (EEC):R36/37/38- Irritating to eyes, respiratory system and skin. S26- In case of contact with eyes, rinse immediately with plenty ofwater and seek medical advice. S36/37/39- Wear suitable protective clothing, gloves and eye/face protection.

HMIS (U.S.A.):

Health Hazard: 1

Fire Hazard: 2

Reactivity: 0

Personal Protection: F


Health: 2

p. 6

Flammability: 2

Reactivity: 0

Specific hazard:

Protective Equipment:Gloves (impervious). Synthetic apron. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wearappropriate respirator when ventilation is inadequate. Safety glasses.




Created: 10/10/2005 08:37 PM

Last Updated: 05/21/2013 12:00 PM


Ethylenediamine Tetraacetic Acid, Disodium Salt

Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt, dihydrate;Ethylenediaminetetraacetic acid disodium salt dihydrate; Ethylenediamine tetraacetic acid disodiumsalt dihydrate; Disodium edetate dihydrate; Glycine, N,N'-1,2-ethanedlylbis[N-(carboxymethyl), disodium salt, dihydrate; Disodium dihydrogen ethylenediamine-N,N,N',N'-tetraacetate, dihydrate; EDTA, disodium, dihydrate; Ethylene diamine tetraacetic acid, disodium salt; Disodium EDTA, dihydrate; Acetic acid, (ethylenedinitrilo)tetra-,disodium salt, dihydratePowder.

CHEMTREC: 800.424.9300Outside US: 703.527.3887

SAFETY DATA SHEET

GHS product identifier

Other means of identification

Product type

Emergency telephone number (with hours of operation)

Section 1. Identification:

:

:

Chemical name : Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, sodium salt, hydrate (1:2:2)

Supplier's details : Thermo Fisher Scientific Pierce BiotechnologyP.O. Box 117Rockford, IL 61105United States815.968.0747 or800.874.37237 AM - 5 PM Central Time (GMT -06:00)


Relevant identified uses of the substance or mixture and uses advised againstNot applicable.

Product codeSDS #

CAS #Chemical formula

:::::

0017892 1879480 1890270 1896264 18966491336C10-H14-N2-O8.2Na.2H2-O6381-92-6

Section 2. Hazards identification

Not classified.Classification of the substance or mixture

:

Signal word : No signal word.Hazard statements : No known significant effects or critical hazards.Precautionary statements

Prevention : Not applicable.Response : Not applicable.Storage : Not applicable.Disposal : Not applicable.

GHS label elements

OSHA/HCS status : While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product.

Hazards not otherwise classified

: Handling and/or processing of this material may generate a dust which can cause mechanical irritation of the eyes, skin, nose and throat.

Date of issue/Date of revision : 8/23/2013. Date of previous issue : No previous validation. Version : 1 1/10


Section 3. Composition/information on ingredients

Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, sodium salt, hydrate (1:2:2)

98 - 100 6381-92-6Ingredient name CAS number%

There are no additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section.

Chemical name : Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, sodium salt, hydrate (1:2:2)Other means of identification

: Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt, dihydrate;Ethylenediaminetetraacetic acid disodium salt dihydrate; Ethylenediamine tetraacetic acid disodiumsalt dihydrate; Disodium edetate dihydrate; Glycine, N,N'-1,2-ethanedlylbis[N-(carboxymethyl), disodium salt, dihydrate; Disodium dihydrogen ethylenediamine-N,N,N',N'-tetraacetate, dihydrate; EDTA, disodium, dihydrate; Ethylene diamine tetraacetic acid, disodium salt; Disodium EDTA, dihydrate; Acetic acid, (ethylenedinitrilo)tetra-,disodium salt, dihydrate

CAS number : 6381-92-6

Substance/mixture

CAS number/other identifiers

:

Occupational exposure limits, if available, are listed in Section 8.

Substance

Any concentration shown as a range is to protect confidentiality or is due to batch variation.

Wash out mouth with water. Remove victim to fresh air and keep at rest in a position comfortable for breathing. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Do not induce vomiting unless directed to do so by medical personnel. Get medical attention if symptoms occur.

Immediately flush eyes with plenty of water, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Get medical attention if irritation occurs.

Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes.Get medical attention if symptoms occur.

Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical attention if symptoms occur. In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours.

Section 4. First aid measures

Eye contact

Skin contact

Inhalation

Ingestion :

:

:

:Description of necessary first aid measures

Most important symptoms/effects, acute and delayed

Inhalation : Exposure to airborne concentrations above statutory or recommended exposure limits may cause irritation of the nose, throat and lungs. Exposure to decomposition products may cause a health hazard. Serious effects may be delayed following exposure.

No known significant effects or critical hazards.:IngestionSkin contact : No known significant effects or critical hazards.

Exposure to airborne concentrations above statutory or recommended exposure limits may cause irritation of the eyes.

:Eye contact

Over-exposure signs/symptoms

Skin contact

Inhalation Adverse symptoms may include the following:respiratory tract irritationcoughingNo specific data.

:

:

Eye contact : Adverse symptoms may include the following:irritationredness

Potential acute health effects



Section 4. First aid measures

Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.

Notes to physician : In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours.

Specific treatments : No specific treatment.

Ingestion No specific data.:

See toxicological information (Section 11)

Indication of immediate medical attention and special treatment needed, if necessary

Section 5. Fire-fighting measures

Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training.

Hazardous thermal decomposition products

Specific hazards arising from the chemical

Decomposition products may include the following materials:carbon dioxidecarbon monoxidenitrogen oxidesmetal oxide/oxides

No specific fire or explosion hazard.

Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Special protective equipment for fire-fighters

Use an extinguishing agent suitable for the surrounding fire.Extinguishing media

:

:

:

May be combustible at high temperature.Remark :

None known.

Suitable extinguishing media

:

Unsuitable extinguishing media

:

Special protective actions for fire-fighters

:

Section 6. Accidental release measures

Environmental precautions

Personal precautions, protective equipment and emergency procedures

Move containers from spill area. Approach release from upwind. Prevent entry into sewers, water courses, basements or confined areas. Vacuum or sweep up material and place in a designated, labeled waste container. Avoid creating dusty conditions and prevent wind dispersal. Dispose of via a licensed waste disposal contractor. Note: see Section 1 for emergency contact information and Section 13 for waste disposal.

:

: No action shall be taken involving any personal risk or without suitable training.Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Avoid breathing dust. Put on appropriate personal protective equipment.

Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air).

Large spill :

Move containers from spill area. Vacuum or sweep up material and place in a designated, labeled waste container. Dispose of via a licensed waste disposal contractor.

Small spill :Methods and materials for containment and cleaning up

For non-emergency personnel

For emergency responders : If specialised clothing is required to deal with the spillage, take note of any information in Section 8 on suitable and unsuitable materials. See also the information in "For non-emergency personnel".



Section 7. Handling and storage

Advice on general occupational hygiene

Conditions for safe storage,including any incompatibilities

Eating, drinking and smoking should be prohibited in areas where this material is handled,stored and processed. Workers should wash hands and face before eating, drinking and smoking. Remove contaminated clothing and protective equipment before entering eating areas. See also Section 8 for additional information on hygiene measures.

Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see Section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination.

:

:

Protective measures Put on appropriate personal protective equipment (see Section 8). Avoid breathing dust.:Precautions for safe handling

None.

Section 8. Exposure controls/personal protection

Hand protection

Use a properly fitted, particulate filter respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator.

Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary.

Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists,gases or dusts. If contact is possible, the following protection should be worn, unless the assessment indicates a higher degree of protection: safety glasses with side-shields. If operating conditions cause high dust concentrations to be produced, use dust goggles.

Eye/face protection

Respiratory protection :

:

:

Body protection Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product.

:

Environmental exposure controls

: Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases,fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels.

Appropriate engineering controls

: Use only with adequate ventilation. If user operations generate dust, fumes, gas, vapor or mist, use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure to airborne contaminants below any recommended or statutory limits.

Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location.

Hygiene measures :

Control parameters

Individual protection measures

Occupational exposure limits

Skin protection

Other skin protection : Appropriate footwear and any additional skin protection measures should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product.



Section 9. Physical and chemical properties

Physical state

Melting point

Vapor pressure

Relative densityVapor density

Solubility

Solid. [Crystalline powder.]

248°C (478.4°F)

Not available.Not available.Not available.

Soluble in the following materials: cold water and hot water.

Odorless.Odor

pH

White.Color

Evaporation rate Not available.

Auto-ignition temperature

Flash point

Not available.

Closed cup: >100°C (>212°F)

Not available.

4 to 6 [Conc. (% w/w): 5%]

Viscosity Not available.

Not available.Odor threshold

Partition coefficient: n-octanol/water

:

::

:

:

:

::

:

:

:

:

:

:

:

Appearance

Boiling point : Not available.

Flammability (solid, gas) : Slightly flammable in the presence of the following materials or conditions: heat.Non-flammable in the presence of the following materials or conditions: shocks and mechanical impacts.May be combustible at high temperature.

Lower and upper explosive (flammable) limits

: Not available.

Burning rate Not available.:Burning time : Not available.

SADT Not available.:Decomposition temperature : >240°C (>464°F)

Solubility in water : 37.22 g/l

Section 10. Stability and reactivity

Hazardous decomposition products

Conditions to avoid No specific data.

Under normal conditions of storage and use, hazardous decomposition products should not be produced.

The product is stable.Chemical stability

No specific data.

:

:

:

Incompatible materials :

Possibility of hazardous reactions

: Under normal conditions of storage and use, hazardous reactions will not occur.

Reactivity : No specific test data related to reactivity available for this product or its ingredients.

Section 11. Toxicological information

Acute toxicityInformation on toxicological effects




Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, sodium salt,hydrate (1:2:2)

LD50 Oral Rat >2000 mg/kg -Product/ingredient name Result Species Dose Exposure

CarcinogenicityNot available.

MutagenicityNot available.

TeratogenicityNot available.

Reproductive toxicityNot available.

Irritation/CorrosionNot available.

SensitizationNot available.

Information on the likely routes of exposure

Inhalation : Exposure to airborne concentrations above statutory or recommended exposure limits may cause irritation of the nose, throat and lungs. Exposure to decomposition products may cause a health hazard. Serious effects may be delayed following exposure.

No known significant effects or critical hazards.:IngestionSkin contact : No known significant effects or critical hazards.

Exposure to airborne concentrations above statutory or recommended exposure limits may cause irritation of the eyes.

:Eye contact

Symptoms related to the physical, chemical and toxicological characteristics

Skin contactIngestion

Inhalation Adverse symptoms may include the following:respiratory tract irritationcoughing

No specific data.No specific data.

:

:

:

Eye contact : Adverse symptoms may include the following:irritationredness

Specific target organ toxicity (single exposure)

Specific target organ toxicity (repeated exposure)

Not available.

Not available.

Aspiration hazardNot available.

: Routes of entry anticipated: Oral, Inhalation.

Potential acute health effects

Classification

Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, sodium salt,hydrate (1:2:2)

None. - -Product/ingredient name NTPIARCOSHA




Not available.

Conclusion/Summary : Exposure can cause stomach pains, vomiting and diarrhea.Repeated or prolonged inhalation of dust may lead to chronic respiratory irritation.General :No known significant effects or critical hazards.Carcinogenicity :No known significant effects or critical hazards.Mutagenicity :No known significant effects or critical hazards.Teratogenicity :

Developmental effects : No known significant effects or critical hazards.Fertility effects : No known significant effects or critical hazards.

Potential chronic health effects

Delayed and immediate effects and also chronic effects from short and long term exposure

Numerical measures of toxicity

Not available.Acute toxicity estimates

Potential immediate effects

: Not available.Short term exposure

Potential delayed effects : Not available.

Potential immediate effects

: Not available.Long term exposure

Potential delayed effects : Not available.

Section 12. Ecological information

Bioaccumulative potential

Other adverse effects : No known significant effects or critical hazards.

Not available.

ToxicityNot available.

Persistence and degradability

Soil/water partition coefficient (KOC)

: Not available.Mobility in soil

Not available.

Section 13. Disposal considerationsThe generation of waste should be avoided or minimized wherever possible. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Waste should not be disposed of untreated to the sewer unless fully compliant with the requirements of all authorities with jurisdiction.Waste packaging should be recycled. Incineration or landfill should only be considered when recycling is not feasible. This material and its container must be disposed of in a safe way. Empty containers or liners may retain some product residues. Avoid dispersal

:Disposal methods



Section 13. Disposal considerationsof spilled material and runoff and contact with soil, waterways, drains and sewers.

Section 14. Transport information

-

-

-

-

Not regulated.

-

-

Not regulated.

- -

DOT Classification IATA

UN number

UN proper shipping name

Transport hazard class(es)

Packing group

Additional information

Environmental hazards

Special precautions for user

Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

No. No.

Transport within user’s premises: always transport in closed containers that are upright and secure. Ensure that persons transporting the product know what to do in the event of an accident or spillage.

: Not available.

:

Section 15. Regulatory informationU.S. Federal regulations :

Clean Air Act Section 112(b) Hazardous Air Pollutants (HAPs)

: Not listed

Clean Air Act Section 602 Class I Substances

: Not listed

Clean Air Act Section 602 Class II Substances

: Not listed

DEA List I Chemicals (Precursor Chemicals)

: Not listed

DEA List II Chemicals (Essential Chemicals)

: Not listed

State regulations

TSCA 8(a) CDR Exempt/Partial exemption: Not determinedUnited States inventory (TSCA 8b): This material is listed or exempted.

SARA 302/304

SARA 304 RQ : Not applicable.

No products were found.

Composition/information on ingredients

SARA 311/312Classification : Not applicable.

No products were found.Composition/information on ingredients



Section 15. Regulatory informationThis material is not listed.Massachusetts :

New York : This material is not listed.New Jersey : This material is not listed.Pennsylvania : This material is not listed.

Canada inventory : This material is listed or exempted.

Australia inventory (AICS): This material is listed or exempted.China inventory (IECSC): This material is listed or exempted.Japan inventory: This material is listed or exempted.Korea inventory: This material is listed or exempted.Malaysia Inventory (EHS Register): Not determined.New Zealand Inventory of Chemicals (NZIoC): This material is listed or exempted.Philippines inventory (PICCS): This material is listed or exempted.Taiwan inventory (CSNN): Not determined.

International regulationsInternational lists :

Chemical Weapons Convention List Schedule I Chemicals

: Not listed

Chemical Weapons Convention List Schedule II Chemicals

: Not listed

Chemical Weapons Convention List Schedule III Chemicals

: Not listed

Section 16. Other information

12/12/2013.History

Date of printing :: 8/23/2013.

Hazardous Material Information System (U.S.A.)0

00

000

National Fire Protection Association (U.S.A.)Health

SpecialInstability/ReactivityFlammability

Health

Flammability

Caution: HMIS® ratings are based on a 0-4 rating scale, with 0 representing minimal hazards or risks, and 4 representing significant hazards or risks Although HMIS® ratings are not required on SDSs under 29 CFR 1910.1200, the preparer may choose to provide them. HMIS® ratings are to be used with a fully implemented HMIS® program. HMIS® is a registered mark of the National Paint & Coatings Association (NPCA). HMIS® materials may be purchased exclusively from J. J. Keller (800) 327-6868.

The customer is responsible for determining the PPE code for this material.

Reprinted with permission from NFPA 704-2001, Identification of the Hazards of Materials for Emergency Response Copyright ©1997, National Fire Protection Association, Quincy, MA 02269. This reprinted material is not the complete and official position of the National Fire Protection Association, on the referenced subject which is represented only by the standard in its entirety.

Copyright ©2001, National Fire Protection Association, Quincy, MA 02269. This warning system is intended to be interpreted and applied only by properly trained individuals to identify fire, health and reactivity hazards of chemicals. The user is referred to certain limited number of chemicals with recommended classifications in NFPA 49 and NFPA 325, which would be used as a guideline only. Whether the chemicals are classified by NFPA or not,anyone using the 704 systems to classify chemicals does so at their own risk.

Physical hazards

Chronic Health Hazard



Section 16. Other informationDate of issue/Date of revision

Version

To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein.Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.

Notice to reader

Date of previous issue::

Indicates information that has changed from previously issued version.References : Not available.

Key to abbreviations : ATE = Acute Toxicity EstimateBCF = Bioconcentration FactorGHS = Globally Harmonized System of Classification and Labelling of ChemicalsIATA = International Air Transport AssociationIBC = Intermediate Bulk ContainerIMDG = International Maritime Dangerous GoodsLogPow = logarithm of the octanol/water partition coefficientMARPOL 73/78 = International Convention for the Prevention of Pollution From Ships,1973 as modified by the Protocol of 1978. ("Marpol" = marine pollution)UN = United Nations

No previous validation.1SDS SpecialistPrepared by :


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Material Safety Data SheetEthidium bromide MSDS


Product Name: Ethidium bromide

Catalog Codes: SLE1144

CAS#: 1239-45-8

RTECS: SF7950000

TSCA: TSCA 8(b) inventory: No products were found.

CI#: Not available.

Synonym: Homidium bromide

Chemical Formula: C21H20BrN3







Ethidium bromide 1239-45-8 100



Potential Acute Health Effects:Hazardous in case of ingestion. Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of inhalation.

Potential Chronic Health Effects:Hazardous in case of ingestion. Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of inhalation.CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available.



Skin Contact:

p. 2

After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with runningwater and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cold water may be used.Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated clothing beforereusing.











Products of Combustion: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenatedcompounds.

Fire Hazards in Presence of Various Substances:Flammable in presence of open flames and sparks. Slightly flammable to flammable in presence of heat.









Precautions:Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under afume hood. Ground all equipment containing material. Do not breathe dust.

Storage:

p. 3

Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly closed. Keep in acool, well-ventilated place. Combustible materials should be stored away from extreme heat and away from strong oxidizingagents.













Boiling Point: Decomposes. (261°C or 501.8°F)











Solubility: Partially soluble in cold water.




p. 4






Polymerization: No.


Routes of Entry: Ingestion.














Waste Disposal:






Federal and State Regulations: TSCA 8(b) inventory: No products were found.

p. 5





HMIS (U.S.A.):

Health Hazard: 1

Fire Hazard: 1

Reactivity: 0



Health: 1

Flammability: 1

Reactivity: 0

Specific hazard:





Created: 10/11/2005 01:15 PM

Last Updated: 05/21/2013 12:00 PM


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Material Safety Data SheetFormaldehyde Solution, Reagnt, ACS MSDS


Product Name: Formaldehyde Solution, Reagnt, ACS

Catalog Codes: SLF2224

CAS#: Mixture.

RTECS: LP8925000

TSCA: TSCA 8(b) inventory: Formaldehyde; Methylalcohol; Water


Synonym: Formalin

Chemical Name: Formaldehyde

Chemical Formula: HCHO







Formaldehyde 50-00-0 36.5-38

Methyl alcohol 67-56-1 10-15

Water 7732-18-5 47-53.5

Toxicological Data on Ingredients: Formaldehyde: ORAL (LD50): Acute: 100 mg/kg [Rat]. 42 mg/kg [Mouse]. 260 mg/kg[Guinea pig]. MIST (LC50): Acute: 454000 mg/m 4 hours [Mouse]. Methyl alcohol: ORAL (LD50): Acute: 5628 mg/kg [Rat].DERMAL (LD50): Acute: 15800 mg/kg [Rabbit]. VAPOR (LC50): Acute: 64000 ppm 4 hours [Rat].


Potential Acute Health Effects:Very hazardous in case of eye contact (irritant), of ingestion, . Hazardous in case of skin contact (irritant, sensitizer,permeator), of eye contact (corrosive). Slightly hazardous in case of skin contact (corrosive). Severe over-exposure can resultin death. Inflammation of the eye is characterized by redness, watering, and itching.

Potential Chronic Health Effects:Hazardous in case of skin contact (sensitizer). CARCINOGENIC EFFECTS: Classified A2 (Suspected for human.) by ACGIH,2A (Probable for human.) by IARC [Formaldehyde]. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells.[Formaldehyde]. Mutagenic for bacteria and/or yeast. [Formaldehyde]. Mutagenic for mammalian somatic cells. [Methyl

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alcohol]. Mutagenic for bacteria and/or yeast. [Methyl alcohol]. TERATOGENIC EFFECTS: Classified POSSIBLE for human[Methyl alcohol]. DEVELOPMENTAL TOXICITY: Not available The substance may be toxic to kidneys, liver, skin, centralnervous system (CNS). Repeated or prolonged exposure to the substance can produce target organs damage. Repeatedexposure to a highly toxic material may produce general deterioration of health by an accumulation in one or many humanorgans.


Eye Contact:Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelidsopen. Cold water may be used. Get medical attention immediately.


Serious Skin Contact:Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate medicalattention.

Inhalation:If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medicalattention immediately.

Serious Inhalation:Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. Ifbreathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. WARNING: It maybe hazardous to the person providing aid to give mouth-to-mouth resuscitation when the inhaled material is toxic, infectious orcorrosive. Seek immediate medical attention.

Ingestion:If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to anunconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention immediately.





Flash Points: CLOSED CUP: 50°C (122°F). OPEN CUP: 60°C (140°F).

Flammable Limits: The greatest known range is LOWER: 6% UPPER: 36.5% (Methyl alcohol)


Fire Hazards in Presence of Various Substances:Flammable in presence of open flames and sparks, of heat. Non-flammable in presence of shocks, of oxidizing materials, ofreducing materials, of combustible materials, of organic materials, of metals, of acids, of alkalis.

Explosion Hazards in Presence of Various Substances: Non-explosive in presence of open flames and sparks, of shocks.

Fire Fighting Media and Instructions:Flammable liquid, soluble or dispersed in water. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use alcohol foam,water spray or fog. Cool containing vessels with water jet in order to prevent pressure build-up, autoignition or explosion.

Special Remarks on Fire Hazards:Explosive in the form of vapor when exposed to heat or flame. Vapor may travel considerable distance to source of ignitionand flash back. When heated to decomposition, it emits acrid smoke and irritating fumes. CAUTION: MAY BURN WITH NEARINVISIBLE FLAME (Methyl alcohol)

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Special Remarks on Explosion Hazards:Reaction with peroxide, nitrogen dioxide, and permformic acid can cause an explosion. (Formaldehyde gas)


Small Spill:Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container. Ifnecessary: Neutralize the residue with a dilute solution of sodium carbonate.

Large Spill:Flammable liquid. Poisonous liquid. Keep away from heat. Keep away from sources of ignition. Stop leak if without risk.Absorb with DRY earth, sand or other non-combustible material. Do not get water inside container. Do not touch spilledmaterial. Use water spray to reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Call forassistance on disposal. Neutralize the residue with a dilute solution of sodium carbonate. Be careful that the product is notpresent at a concentration level above TLV. Check TLV on the MSDS and with local authorities.


Precautions:Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Donot breathe gas/fumes/ vapor/spray. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested,seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes. Keep away fromincompatibles such as oxidizing agents, reducing agents, acids, alkalis, moisture.

Storage:Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly closed andsealed until ready for use. Avoid all possible sources of ignition (spark or flame).



Personal Protection:Safety glasses. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves (impervious).


Exposure Limits:Formaldehyde gas STEL: 0.3 (ppm) from ACGIH (TLV) [United States] STEL: 0.37 (mg/m3) from ACGIH (TLV) [United States]TWA: 0.75 STEL: 2 (ppm) from OSHA (PEL) [United States] TWA: 2 STEL: 2 (ppm) [United Kingdom (UK)] TWA: 2.5 STEL:2.5 (mg/m3) [United Kingdom (UK)] Methyl alcohol TWA: 200 from OSHA (PEL) [United States] TWA: 200 STEL: 250 (ppm)from ACGIH (TLV) [United States] [1999] STEL: 250 from NIOSH [United States] TWA: 200 STEL: 250 (ppm) from NIOSHSKIN TWA: 200 STEL: 250 (ppm) [Canada] Consult local authorities for acceptable exposure limits.



Odor: Pungent. Suffocating. (Strong.)


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Molecular Weight: 30.02


pH (1% soln/water): 3 [Acidic.] pH of the solution as is.


Melting Point: -15°C (5°F)

Critical Temperature: The lowest known value is 240°C (464°F) (Methyl alcohol).




Volatility: 100% (w/w).

Odor Threshold: The highest known value is 100 ppm (Methyl alcohol)


Ionicity (in Water): Non-ionic.


Solubility:Easily soluble in cold water, hot water. Soluble in diethyl ether, acetone, alcohol




Conditions of Instability: Heat, ignition sources (flames, sparks), incompatible materials

Incompatibility with various substances:Reactive with oxidizing agents, reducing agents, acids, alkalis. Slightly reactive to reactive with metals.


Special Remarks on Reactivity:Also incompatible with urea, phenol, isocyanates, anhydrides, amines, AZO compounds, carbonyl compounds, oxides(e.g.nitrogen dioxide), performic acid, dithiocarbmates, or peroxides. Polymerization can be inhibited by the addition of methanol orstabilizers such as hydorxypropyl methyl cellulose, methyl ethyl celluloses, or isophthalobisguanamine.




Routes of Entry: Absorbed through skin. Dermal contact. Eye contact. Inhalation.

Toxicity to Animals:Acute oral toxicity (LD50): 42 mg/kg [Mouse]. (Formaldehyde) Acute dermal toxicity (LD50): 15800 mg/kg [Rabbit]. (Methylalcohol). Acute toxicity of the mist(LC50): 454000 mg/m 4 hours [Mouse]. (Formaldehyde) 3

Chronic Effects on Humans:CARCINOGENIC EFFECTS: Classified A2 (Suspected for human.) by ACGIH, 2A (Probable for human.) by IARC[Formaldehyde]. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. [Formaldehyde]. Mutagenic for bacteriaand/or yeast. [Formaldehyde]. Mutagenic for mammalian somatic cells. [Methyl alcohol]. Mutagenic for bacteria and/oryeast. [Methyl alcohol]. TERATOGENIC EFFECTS: Classified POSSIBLE for human [Methyl alcohol]. DEVELOPMENTALTOXICITY: Not available May cause damage to the following organs: kidneys, liver, central nervous system (CNS).

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Other Toxic Effects on Humans:Very hazardous in case of ingestion, . Hazardous in case of skin contact (irritant, sensitizer, permeator), of eye contact(corrosive), of inhalation (lung corrosive). Slightly hazardous in case of skin contact (corrosive).

Special Remarks on Toxicity to Animals:Formaldehyde: LD50 [Rabbit] - Route: Skin; Dose: 270 ul/kg

Special Remarks on Chronic Effects on Humans:Exposure to Formaldehyde and Methanol may affect genetic material (mutagenic). Exposure to Formaldehyde and Methanolmay cause adverse reproductive effects and birth defects(teratogenic). Adverse reproductive effects of Formaldehyde as wellas Methanol are primarily based on animal studies. Very few human studies have been done on the adverse reproductiveeffects from exposure to Formaldehyde. Studies produced a weak association (limited evidence) between advese humanfemale reproductive effects and occupational exposure. Furthermore, no human data could be found on adverse reproductiveeffects from occupational exposure to Methanol. Exposure to Formaldehyde may cause cancer.

Special Remarks on other Toxic Effects on Humans:Acute Potential Health Effects: Skin: Corrosive. Causes skin irritation which may range from mild to severe with possible burnsdepending on the extent of exposure and concentration of solution. Other symptoms may include brownish discoloration of theskin, urticaria, and pustulovesicffular eruptions. May be absorbed through skin with symptoms paralleling those of ingestion.Eyes: Corrosive. Contact with liquid causes severe eye irritation and burns. It may cause irreversible eye damage (severecorneal Solutions containing low formaldehyde concentrations may produce transient discomfort and irritation. Inhalation:Causes irrititation of the respiratory tract (nose, throat, airways). Symptoms may include dry and sore mouth and throat,thirst, and sleep disturbances, difficulty breathing, shortness of breath, coughing, sneezing, wheezing rhinitis, chest tightness,pulmonary edema, bronchitis, tracheitis, laryngospasm, pneumonia, palpitations. It may also affect metabolism weightloss, metabolic acidosis), behavior/central nervous system (excitement, central nervous system depression, somnolence,convulsions, stupor, aggression, headache, weakness, dizziness, drowsiness, coma), peripheral nervous system, and blood.Ingestion: Harmful if swallowed. May be fatal. Causes gastrointestinal irritation with nausea, vomiting (possibly with blood),diarrhea, severe pain in mouth, throat and stomach, and possible corrosive injury to the gastrointestinal mucosa/ulcerationor bleeding from stomach. May also affect the liver(jaundice), urinary system/kidneys (difficulty urinating, albuminuria,hematuria, anuria), blood, endocrine system, respiration (respiratory obstruction, pulmonary edema, bronchiolar obstruction),cardiovascular system (hypotension), metabolism (metabolic acidosis), eyes (retinal changes, visual field changes), andbehavior/central nervous system (symptoms similar to those for inhalation). Contains Methanol which may cause blindness ifswallowed. Chronic Potential Health Effects: Skin: Prolonged or repeated exposure may cause contact dermatits both irritantand allergic. It may also cause skin discoloration. Inhalation: Although there is no clear evidence, prolonged or repeatedexposure may induce allergic asthma. Other effects are similar to that of acute exposure. Ingestion: Prolonged or repeatedingestion may cause gastrointestinal tract irritation and ulceration or bleeding from the stomach. Other effects may be similarto that of acute ingestion.





Toxicity of the Products of Biodegradation: The products of degradation are less toxic than the product itself.

Special Remarks on the Products of Biodegradation:Methanol in water is rapidly biodegraded and volatilized. Aquatic hydrolysis, oxidation, photolysis, adsorption to sediment, andbioconcentration are not significant fate processes. The half-life of methanol in surfact water ranges from 24 hrs. to 168 hrs.Based on its vapor pressure, methanol exists almost entirely in the vapor phase in the ambient atmosphere. It is degraded byreaction with photochemically produced hydroxyl radicals and has an estimated half-life of 17.8 days. Methanol is physicallyremoved from air by rain due to its solubility. Methanol can react with NO2 in pollulted to form methyl nitrate. The half-life ofmethanol in air ranges from 71 hrs. (3 days) to 713 hrs. (29.7 days) based on photooxidation half-life in air. (Methyl alcohol)


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DOT Classification:CLASS 3: Flammable liquid. Class 8: Corrosive material

Identification: : Formaldehyde Solution, flammable (Methyl alcohol) UNNA: 1198 PG: III



Federal and State Regulations:California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer,birth defects or other reproductive harm, which would require a warning under the statute: Formaldehyde California prop.65 (no significant risk level): Formaldehyde: 0.04 mg/day (inhalation) California prop. 65: This product contains the followingingredients for which the State of California has found to cause cancer which would require a warning under the statute:Formaldehyde Solution Connecticut hazardous material survey.: Formaldehyde; Methyl alcohol Illinois toxic substancesdisclosure to employee act: Formaldehyde; Methyl alcohol Illinois chemical safety act: Formaldehyde; Methyl alcohol NewYork release reporting list: Formaldehyde; Methyl alcohol Rhode Island RTK hazardous substances: Formaldehyde; Methylalcohol Pennsylvania RTK: Formaldehyde; Methyl alcohol Minnesota: Formaldehyde gas; Methyl alcohol MassachusettsRTK: Formaldehyde; Methyl alcohol Massachusetts spill list: Formaldehyde; Methyl alcohol New Jersey: Formaldehyde;Methyl alcohol New Jersey spill list: Formaldehyde; Methyl alcohol Louisiana RTK reporting list: Formaldehyde Louisiana spillreporting: Formaldehyde; Methyl alcohol California Director's List of Hazardous Substances: Formaldehyde; Methyl alcoholTSCA 8(b) inventory: Formaldehyde gas; Methyl alcohol; Water TSCA 4(f) priority risk review: Formaldehyde, Reagnt, ACSSARA 302/304/311/312 extremely hazardous substances: Formaldehyde SARA 313 toxic chemical notification and releasereporting: Formaldehyde; Methyl alcohol CERCLA: Hazardous substances.: Formaldehyde: 100 lbs. (45.36 kg); Methylalcohol: 5000 lbs. (2268 kg);



WHMIS (Canada):CLASS B-3: Combustible liquid with a flash point between 37.8°C (100°F) and 93.3°C (200°F). CLASS D-1A: Material causingimmediate and serious toxic effects (VERY TOXIC). CLASS D-2A: Material causing other toxic effects (VERY TOXIC).

DSCL (EEC):

HMIS (U.S.A.):

Health Hazard: 3

Fire Hazard: 2

Reactivity: 0

Personal Protection: G


Health: 3

Flammability: 2

Reactivity: 0

Specific hazard:

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Protective Equipment:Gloves (impervious). Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wearappropriate respirator when ventilation is inadequate. Safety glasses.




Created: 10/09/2005 05:35 PM

Last Updated: 05/21/2013 12:00 PM


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Material Safety Data SheetFormaldehyde 37% solution MSDS


Product Name: Formaldehyde 37% solution

Catalog Codes: SLF1426

CAS#: Mixture.

RTECS: LP8925000

TSCA: TSCA 8(b) inventory: Formaldehyde; Methylalcohol; Water


Synonym: Formalin

Chemical Name: Formaldehyde

Chemical Formula: HCHO







Formaldehyde 50-00-0 36.5-38

Methyl alcohol 67-56-1 10-15

Water 7732-18-5 47-53.5

Toxicological Data on Ingredients: Formaldehyde: ORAL (LD50): Acute: 100 mg/kg [Rat]. 42 mg/kg [Mouse]. 260 mg/kg[Guinea pig]. MIST (LC50): Acute: 454000 mg/m 4 hours [Mouse]. Methyl alcohol: ORAL (LD50): Acute: 5628 mg/kg [Rat].DERMAL (LD50): Acute: 15800 mg/kg [Rabbit]. VAPOR (LC50): Acute: 64000 ppm 4 hours [Rat].


Potential Acute Health Effects:Very hazardous in case of eye contact (irritant), of ingestion, . Hazardous in case of skin contact (irritant, sensitizer,permeator), of eye contact (corrosive). Slightly hazardous in case of skin contact (corrosive). Severe over-exposure can resultin death. Inflammation of the eye is characterized by redness, watering, and itching.

Potential Chronic Health Effects:Hazardous in case of skin contact (sensitizer). CARCINOGENIC EFFECTS: Classified A2 (Suspected for human.) by ACGIH,2A (Probable for human.) by IARC [Formaldehyde]. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells.[Formaldehyde]. Mutagenic for bacteria and/or yeast. [Formaldehyde]. Mutagenic for mammalian somatic cells. [Methyl

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alcohol]. Mutagenic for bacteria and/or yeast. [Methyl alcohol]. TERATOGENIC EFFECTS: Classified POSSIBLE for human[Methyl alcohol]. DEVELOPMENTAL TOXICITY: Not available The substance may be toxic to kidneys, liver, skin, centralnervous system (CNS). Repeated or prolonged exposure to the substance can produce target organs damage. Repeatedexposure to a highly toxic material may produce general deterioration of health by an accumulation in one or many humanorgans.


Eye Contact:Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelidsopen. Cold water may be used. Get medical attention immediately.










Flash Points: CLOSED CUP: 50°C (122°F). OPEN CUP: 60°C (140°F).

Flammable Limits: The greatest known range is LOWER: 6% UPPER: 36.5% (Methyl alcohol)


Fire Hazards in Presence of Various Substances:Flammable in presence of open flames and sparks, of heat. Non-flammable in presence of shocks, of oxidizing materials, ofreducing materials, of combustible materials, of organic materials, of metals, of acids, of alkalis.


Fire Fighting Media and Instructions:Flammable liquid, soluble or dispersed in water. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use alcohol foam,water spray or fog. Cool containing vessels with water jet in order to prevent pressure build-up, autoignition or explosion.

Special Remarks on Fire Hazards:Explosive in the form of vapor when exposed to heat or flame. Vapor may travel considerable distance to source of ignitionand flash back. When heated to decomposition, it emits acrid smoke and irritating fumes. CAUTION: MAY BURN WITH NEARINVISIBLE FLAME (Methyl alcohol)

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Special Remarks on Explosion Hazards:Reaction with peroxide, nitrogen dioxide, and permformic acid can cause an explosion. (Formaldehyde gas)



Large Spill:Flammable liquid. Poisonous liquid. Keep away from heat. Keep away from sources of ignition. Stop leak if without risk.Absorb with DRY earth, sand or other non-combustible material. Do not get water inside container. Do not touch spilledmaterial. Use water spray to reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Call forassistance on disposal. Neutralize the residue with a dilute solution of sodium carbonate. Be careful that the product is notpresent at a concentration level above TLV. Check TLV on the MSDS and with local authorities.


Precautions:Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Donot breathe gas/fumes/ vapor/spray. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested,seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes. Keep away fromincompatibles such as oxidizing agents, reducing agents, acids, alkalis, moisture.

Storage:Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly closed andsealed until ready for use. Avoid all possible sources of ignition (spark or flame).



Personal Protection:Safety glasses. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves (impervious).


Exposure Limits:Formaldehyde gas STEL: 0.3 (ppm) from ACGIH (TLV) [United States] STEL: 0.37 (mg/m3) from ACGIH (TLV) [United States]TWA: 0.75 STEL: 2 (ppm) from OSHA (PEL) [United States] TWA: 2 STEL: 2 (ppm) [United Kingdom (UK)] TWA: 2.5 STEL:2.5 (mg/m3) [United Kingdom (UK)] Methyl alcohol TWA: 200 from OSHA (PEL) [United States] TWA: 200 STEL: 250 (ppm)from ACGIH (TLV) [United States] [1999] STEL: 250 from NIOSH [United States] TWA: 200 STEL: 250 (ppm) from NIOSHSKIN TWA: 200 STEL: 250 (ppm) [Canada] Consult local authorities for acceptable exposure limits.



Odor: Pungent. Suffocating. (Strong.)


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Molecular Weight: 30.02


pH (1% soln/water): 3 [Acidic.] pH of the solution as is.


Melting Point: -15°C (5°F)

Critical Temperature: The lowest known value is 240°C (464°F) (Methyl alcohol).




Volatility: 100% (w/w).

Odor Threshold: The highest known value is 100 ppm (Methyl alcohol)


Ionicity (in Water): Non-ionic.


Solubility:Easily soluble in cold water, hot water. Soluble in diethyl ether, acetone, alcohol




Conditions of Instability: Heat, ignition sources (flames, sparks), incompatible materials

Incompatibility with various substances:Reactive with oxidizing agents, reducing agents, acids, alkalis. Slightly reactive to reactive with metals.


Special Remarks on Reactivity:Also incompatible with urea, phenol, isocyanates, anhydrides, amines, AZO compounds, carbonyl compounds, oxides(e.g.nitrogen dioxide), performic acid, dithiocarbmates, or peroxides. Polymerization can be inhibited by the addition of methanol orstabilizers such as hydorxypropyl methyl cellulose, methyl ethyl celluloses, or isophthalobisguanamine.





Toxicity to Animals:Acute oral toxicity (LD50): 42 mg/kg [Mouse]. (Formaldehyde) Acute dermal toxicity (LD50): 15800 mg/kg [Rabbit]. (Methylalcohol). Acute toxicity of the mist(LC50): 454000 mg/m 4 hours [Mouse]. (Formaldehyde) 3

Chronic Effects on Humans:CARCINOGENIC EFFECTS: Classified A2 (Suspected for human.) by ACGIH, 2A (Probable for human.) by IARC[Formaldehyde]. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. [Formaldehyde]. Mutagenic for bacteriaand/or yeast. [Formaldehyde]. Mutagenic for mammalian somatic cells. [Methyl alcohol]. Mutagenic for bacteria and/oryeast. [Methyl alcohol]. TERATOGENIC EFFECTS: Classified POSSIBLE for human [Methyl alcohol]. DEVELOPMENTALTOXICITY: Not available May cause damage to the following organs: kidneys, liver, central nervous system (CNS).

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Other Toxic Effects on Humans:Very hazardous in case of ingestion, . Hazardous in case of skin contact (irritant, sensitizer, permeator), of eye contact(corrosive), of inhalation (lung corrosive). Slightly hazardous in case of skin contact (corrosive).

Special Remarks on Toxicity to Animals:Formaldehyde: LD50 [Rabbit] - Route: Skin; Dose: 270 ul/kg

Special Remarks on Chronic Effects on Humans:Exposure to Formaldehyde and Methanol may affect genetic material (mutagenic). Exposure to Formaldehyde and Methanolmay cause adverse reproductive effects and birth defects(teratogenic). Adverse reproductive effects of Formaldehyde as wellas Methanol are primarily based on animal studies. Very few human studies have been done on the adverse reproductiveeffects from exposure to Formaldehyde. Studies produced a weak association (limited evidence) between advese humanfemale reproductive effects and occupational exposure. Furthermore, no human data could be found on adverse reproductiveeffects from occupational exposure to Methanol. Exposure to Formaldehyde may cause cancer.

Special Remarks on other Toxic Effects on Humans:Acute Potential Health Effects: Skin: Corrosive. Causes skin irritation which may range from mild to severe with possible burnsdepending on the extent of exposure and concentration of solution. Other symptoms may include brownish discoloration of theskin, urticaria, and pustulovesicffular eruptions. May be absorbed through skin with symptoms paralleling those of ingestion.Eyes: Corrosive. Contact with liquid causes severe eye irritation and burns. It may cause irreversible eye damage (severecorneal Solutions containing low formaldehyde concentrations may produce transient discomfort and irritation. Inhalation:Causes irrititation of the respiratory tract (nose, throat, airways). Symptoms may include dry and sore mouth and throat,thirst, and sleep disturbances, difficulty breathing, shortness of breath, coughing, sneezing, wheezing rhinitis, chest tightness,pulmonary edema, bronchitis, tracheitis, laryngospasm, pneumonia, palpitations. It may also affect metabolism weightloss, metabolic acidosis), behavior/central nervous system (excitement, central nervous system depression, somnolence,convulsions, stupor, aggression, headache, weakness, dizziness, drowsiness, coma), peripheral nervous system, and blood.Ingestion: Harmful if swallowed. May be fatal. Causes gastrointestinal irritation with nausea, vomiting (possibly with blood),diarrhea, severe pain in mouth, throat and stomach, and possible corrosive injury to the gastrointestinal mucosa/ulcerationor bleeding from stomach. May also affect the liver(jaundice), urinary system/kidneys (difficulty urinating, albuminuria,hematuria, anuria), blood, endocrine system, respiration (respiratory obstruction, pulmonary edema, bronchiolar obstruction),cardiovascular system (hypotension), metabolism (metabolic acidosis), eyes (retinal changes, visual field changes), andbehavior/central nervous system (symptoms similar to those for inhalation). Contains Methanol which may cause blindness ifswallowed. Chronic Potential Health Effects: Skin: Prolonged or repeated exposure may cause contact dermatits both irritantand allergic. It may also cause skin discoloration. Inhalation: Although there is no clear evidence, prolonged or repeatedexposure may induce allergic asthma. Other effects are similar to that of acute exposure. Ingestion: Prolonged or repeatedingestion may cause gastrointestinal tract irritation and ulceration or bleeding from the stomach. Other effects may be similarto that of acute ingestion.






Special Remarks on the Products of Biodegradation:Methanol in water is rapidly biodegraded and volatilized. Aquatic hydrolysis, oxidation, photolysis, adsorption to sediment, andbioconcentration are not significant fate processes. The half-life of methanol in surfact water ranges from 24 hrs. to 168 hrs.Based on its vapor pressure, methanol exists almost entirely in the vapor phase in the ambient atmosphere. It is degraded byreaction with photochemically produced hydroxyl radicals and has an estimated half-life of 17.8 days. Methanol is physicallyremoved from air by rain due to its solubility. Methanol can react with NO2 in pollulted to form methyl nitrate. The half-life ofmethanol in air ranges from 71 hrs. (3 days) to 713 hrs. (29.7 days) based on photooxidation half-life in air. (Methyl alcohol)


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DOT Classification:CLASS 3: Flammable liquid. Class 8: Corrosive material

Identification: : Formaldehyde Solution, flammable (Methyl alcohol) UNNA: 1198 PG: III



Federal and State Regulations:California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer,birth defects or other reproductive harm, which would require a warning under the statute: Formaldehyde California prop.65 (no significant risk level): Formaldehyde: 0.04 mg/day (inhalation) California prop. 65: This product contains the followingingredients for which the State of California has found to cause cancer which would require a warning under the statute:Formaldehyde Solution Connecticut hazardous material survey.: Formaldehyde; Methyl alcohol Illinois toxic substancesdisclosure to employee act: Formaldehyde; Methyl alcohol Illinois chemical safety act: Formaldehyde; Methyl alcohol NewYork release reporting list: Formaldehyde; Methyl alcohol Rhode Island RTK hazardous substances: Formaldehyde; Methylalcohol Pennsylvania RTK: Formaldehyde; Methyl alcohol Minnesota: Formaldehyde gas; Methyl alcohol MassachusettsRTK: Formaldehyde; Methyl alcohol Massachusetts spill list: Formaldehyde; Methyl alcohol New Jersey: Formaldehyde;Methyl alcohol New Jersey spill list: Formaldehyde; Methyl alcohol Louisiana RTK reporting list: Formaldehyde Louisiana spillreporting: Formaldehyde; Methyl alcohol California Director's List of Hazardous Substances: Formaldehyde; Methyl alcoholTSCA 8(b) inventory: Formaldehyde gas; Methyl alcohol; Water TSCA 4(f) priority risk review: Formaldehyde, Reagnt, ACSSARA 302/304/311/312 extremely hazardous substances: Formaldehyde SARA 313 toxic chemical notification and releasereporting: Formaldehyde; Methyl alcohol CERCLA: Hazardous substances.: Formaldehyde: 100 lbs. (45.36 kg); Methylalcohol: 5000 lbs. (2268 kg);



WHMIS (Canada):CLASS B-3: Combustible liquid with a flash point between 37.8°C (100°F) and 93.3°C (200°F). CLASS D-1A: Material causingimmediate and serious toxic effects (VERY TOXIC). CLASS D-2A: Material causing other toxic effects (VERY TOXIC).

DSCL (EEC):

HMIS (U.S.A.):

Health Hazard: 3

Fire Hazard: 2

Reactivity: 0

Personal Protection: G


Health: 3

Flammability: 2

Reactivity: 0

Specific hazard:

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Protective Equipment:Gloves (impervious). Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wearappropriate respirator when ventilation is inadequate. Safety glasses.




Created: 10/09/2005 05:35 PM

Last Updated: 05/21/2013 12:00 PM


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Material Safety Data SheetGlycerol Formal MSDS


Product Name: Glycerol Formal

Catalog Codes: SLG1555

CAS#: 4740-78-7 and 5464-28-8

RTECS: JH8390000


CI#: Not available.

Synonym: Glycerol formal is a mixture of isomeric alphaand beta forms prepared from glycerin and formaldehyde;Methylidinoglycerol; Glicerinformal; Sericosol

Chemical Name: Glycerol Formal

Chemical Formula: C4-H8-O3







Glycerol Formal 4740-78-7 and 100

5464-28-8

Toxicological Data on Ingredients: Glycerol Formal: ORAL (LD50): Acute: 8000 mg/kg [Mouse] [RTECS data for 1,3-dioxolane-4-methanol (the isomeric beta form)].


Potential Acute Health Effects: Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation.



Eye Contact:

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Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Get medical attention.

Skin Contact:In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminatedclothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.









Flash Points: CLOSED CUP: 97°C (206.6°F).



Fire Hazards in Presence of Various Substances:Slightly flammable to flammable in presence of open flames and sparks, of heat. Non-flammable in presence of shocks.






Small Spill: Absorb with an inert material and put the spilled material in an appropriate waste disposal.

Large Spill:Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by spreading wateron the contaminated surface and allow to evacuate through the sanitary system.


Precautions:Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under afume hood. Ground all equipment containing material. Do not ingest. Do not breathe gas/fumes/ vapor/spray. Wear suitable

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protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical adviceimmediately and show the container or the label. Avoid contact with skin and eyes. Keep away from incompatibles such asoxidizing agents.

Storage:Hygroscopic. Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 24°C (75.2°F).








Odor: Odorless.



Color: Colorless.






Vapor Pressure: Not available.







Solubility: Organic solvents



p. 4


Conditions of Instability: Excess heat, incompatible materials, moisture

Incompatibility with various substances: Reactive with oxidizing agents.


Special Remarks on Reactivity: Hygroscopic




Routes of Entry: Absorbed through skin. Eye contact.

Toxicity to Animals:Acute oral toxicity (LD50): 8000 mg/kg [Mouse [RTECS data for 1,3-dioxolane-4-methanol (the isomeric beta form)]].


Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant), of ingestion, of inhalation.


Special Remarks on Chronic Effects on Humans:According to the RTECS database, the isomeric beta form (1,3-Dioxolane-4-methanol )may cause adverse reproductiveeffects (female fertility), and birth defects based on animal data. No information was found for the alpha and beta mixture

Special Remarks on other Toxic Effects on Humans:Acute Potential Health Effects: Skin: May cause skin irritation. Eyes: Dust may cause eye irritation. Inhalation: May causerespiratory tract irritation. Ingestion: May cause gastrointestinal (digestive) tract irritation. According to the RTECS database,the isomeric beta form (1,3-Dioxolane-4methanol) may affect behavior if ingested. Chronic Potential Health Effects: noinformation found. The toxicological properties of this substance have not been fully investigated.












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Federal and State Regulations: No products were found.

Other Regulations: EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.


WHMIS (Canada): CLASS D-2B: Material causing other toxic effects (TOXIC).

DSCL (EEC):R36/38- Irritating to eyes and skin. S24/25- Avoid contact with skin and eyes. S28- After contact with skin, wash immediatelywith plenty of water. S37- Wear suitable gloves. S45- In case of accident or if you feel unwell, seek medical adviceimmediately (show the label where possible).

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 1

Reactivity: 0



Health: 1

Flammability: 1

Reactivity: 0

Specific hazard:





Created: 10/09/2005 05:39 PM

Last Updated: 05/21/2013 12:00 PM


SAFETY DATA SHEET

Issuing Date 02-Jun-2010 Revision Date 08-Jan-2016 Revision Number 2

1. PRODUCT AND COMPANY IDENTIFICATION

Product Identifier Product Name Glycerol

Other means of identification Product Code(s) E520Synonyms No information available

Recommended use of the chemical and restrictions on use Recommended Use For Further Manufacturing Use Only.Uses advised against Not for Human or Animal Drug Use

Details of the supplier of the safety data sheet

Company Phone Number 1-800-448-4442E-mail Address [email protected]

Emergency Telephone Number Emergency Telephone Number Chemtrec 1-800-424-9300

2. HAZARDS IDENTIFICATION

Classification

OSHA Regulatory StatusThis chemical is not considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.122)

Label elements

Emergency Overview

Hazards not otherwise classified (HNOC) Not regulatedOther Information • May be harmful if inhaledUnknown Acute Toxicity 0 % of the mixture consists of ingredient(s) of unknown toxicity

3. COMPOSITION/INFORMATION ON INGREDIENTS

Chemical Name CAS-No EC No. Weight % Trade SecretGlycerol 56-81-5 200-289-5 95-100 Not applicable

Company AddressVWR International, LLCRadnor Corporate Center100 Matsonford RoadRadnor, PA 19087-8660

Manufacturer AddressVWR International, LLC28600 Fountain ParkwaySolon, Ohio 44139

Appearance Viscous Physical State Liquid

_____________________________________________________________________________________________

Page 1 / 7

Odor No information available

_____________________________________________________________________________________________Product Code(s)E520 - Glycerol Revision Date 08-Jan-2016

4. FIRST AID MEASURES

First Aid Measures

Eye Contact Rinse thoroughly with plenty of water for at least 15 minutes, lifting lower and upper eyelids.Consult a physician.

Skin Contact Wash off immediately with soap and plenty of water removing all contaminated clothes andshoes.

Inhalation Move to fresh air. If not breathing, give artificial respiration.

Ingestion Never give anything by mouth to an unconscious person. Rinse mouth.

Most important symptoms and effects, both acute and delayed

Most Important Symptoms/Effects No information available.

Indication of any immediate medical attention and special treatment needed

Notes to Physician Treat symptomatically.

5. FIRE-FIGHTING MEASURES

Suitable Extinguishing MediaUse extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Unsuitable Extinguishing Media No information available.

Specific Hazards Arising from the ChemicalNo information available.

Hazardous CombustionProducts

Carbon oxides.

Explosion Data Sensitivity to Mechanical Impact None.Sensitivity to Static Discharge None.

Protective Equipment and Precautions for FirefightersAs in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and fullprotective gear.

6. ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures

Personal protection Ensure adequate ventilation, especially in confined areas.

Environmental Precautions

Environmental Precautions See Section 12 for additional Ecological information.

Methods and material for containment and cleaning up

Methods for Containment Prevent further leakage or spillage if safe to do so.

Methods for Cleaning Up Absorb on sand or vermiculite and place in closed containers for disposal. Pick up andtransfer to properly labeled containers. Ventilate area and wash spill site after materialpickup is complete.

_____________________________________________________________________________________________

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7. HANDLING AND STORAGE


Precautions for Safe Handling

Handling Handle in accordance with good industrial hygiene and safety practice. Hygroscopic.

Conditions for safe storage, including any incompatibilities

Storage Keep containers tightly closed in a dry, cool and well-ventilated place. Hygroscopic.

Incompatible Products Strong oxidizing agents. Strong bases.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Control parameters

Exposure Guidelines .Chemical Name ACGIH TLV OSHA PEL NIOSH IDLH

Glycerol 56-81-5

- TWA: 15 mg/m3

TWA: 5 mg/m3-

Appropriate engineering controls

Engineering Measures ShowersEyewash stationsVentilation systems.

Individual protection measures, such as personal protective equipment

Eye/Face Protection Avoid contact with eyes. Safety glasses with side-shields.

Skin and Body Protection Wear protective gloves/clothing.

Respiratory Protection If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approvedrespiratory protection should be worn. Positive-pressure supplied air respirators may berequired for high airborne contaminant concentrations. Respiratory protection must beprovided in accordance with current local regulations.

Hygiene Measures Handle in accordance with good industrial hygiene and safety practice.

9. PHYSICAL AND CHEMICAL PROPERTIES

Information on basic physical and chemical properties

Physical State LiquidAppearance Viscous Odor No information availableColor No information available Odor Threshold No information available

Property Values Remarks • Method pH 5.5 - 8Melting point/freezing point 20 °C / 68 °FBoiling Point/Range 182 °C / 360 °FFlash Point (High in °C) 160 °C / 320 °F Closed cupEvaporation Rate No information availableFlammability (solid, gas) No information availableFlammability Limit in Air

Upper flammability limit: No information availableLower flammability limit: No information available

Vapor pressure No information availableVapor Density No information availableSpecific Gravity 1.261Water Solubility No information availableSolubility in other solvents No information availablePartition coefficient No information available

_____________________________________________________________________________________________

Page 3 / 7


Explosive Properties No information availableOxidizing Properties No information available

Other Information

Softening Point No information availableMolecular Weight No information availableVOC Content No information availableDensity 3.1Bulk Density No information available

10. STABILITY AND REACTIVITY

Reactivity

Chemical StabilityStable under recommended storage conditions.Possibility of Hazardous ReactionsNone under normal processing.Conditions to AvoidExtremes of temperature and direct sunlight.Incompatible MaterialsStrong oxidizing agents. Strong bases.Hazardous Decomposition ProductsNone known based on information supplied.

11. TOXICOLOGICAL INFORMATION

Information on likely routes of exposure

Product Information

Inhalation There is no data available for this product.

Eye Contact There is no data available for this product.

Skin Contact There is no data available for this product.

Ingestion There is no data available for this product.

Chemical Name LD50 Oral LD50 Dermal LC50 InhalationGlycerol 56-81-5

= 12600 mg/kg ( Rat ) > 10 g/kg ( Rabbit ) > 570 mg/m3 ( Rat ) 1 h

Information on toxicological effects

Symptoms No information available.

Delayed and immediate effects as well as chronic effects from short and long-term exposure

Sensitization No information available.Mutagenic Effects No information available.Carcinogenicity No information available.Chemical Name ACGIH IARC NTP OSHAGlycerol 56-81-5

- - - -

Reproductive Toxicity No information available.

Autoignition Temperature 369 °C / 698 °FDecomposition Temperature No information availableKinematic viscosity No information availableDynamic viscosity No information available

No data available

_____________________________________________________________________________________________

Page 4 / 7


STOT - single exposure No information available.STOT - repeated exposure No information available.Aspiration hazard No information available.

Numerical measures of toxicity - Product Information

Unknown Acute Toxicity 0 % of the mixture consists of ingredient(s) of unknown toxicityThe following values are calculated based on chapter 3.1 of the GHS document .

12. ECOLOGICAL INFORMATION

Ecotoxicity

0% of the mixture consists of components(s) of unknown hazards to the aquatic environmentChemical Name Algae/aquatic plants Toxicity to Fish Crustacea

Glycerol 56-81-5

- 51 - 57: 96 h Oncorhynchus mykissmL/L LC50 static

500: 24 h Daphnia magna mg/LEC50

Persistence and DegradabilityNo information available.

Bioaccumulation/AccumulationNo information available.

Chemical Name Partition coefficientGlycerol 56-81-5

-1.76

Other Adverse Effects No information available

13. DISPOSAL CONSIDERATIONS

Waste treatment methods

Waste Disposal Method Dispose of material in accordance with all federal, state, and local regulations.

Contaminated Packaging Do not re-use empty containers.

Chemical Name RCRA - HalogenatedOrganic Compounds

RCRA - P Series Wastes RCRA - F Series Wastes RCRA - K Series Wastes

Glycerol 56-81-5

- - - -

Chemical Name California Hazardous Waste StatusGlycerol 56-81-5

-

14. TRANSPORT INFORMATION

DOT Not regulated

IATA Not regulated

15. REGULATORY INFORMATIONInternational Inventories TSCA CompliesDSL/NDSL CompliesEINECS/ELINCS Complies

_____________________________________________________________________________________________

Page 5 / 7


ENCS CompliesIECSC CompliesKECL CompliesPICCS CompliesAICS Complies

Legend: TSCA - United States Toxic Substances Control Act Section 8(b) InventoryDSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances ListEINECS/ELINCS - European Inventory of Existing Commercial Chemical Substances/EU List of Notified Chemical SubstancesENCS - Japan Existing and New Chemical SubstancesIECSC - China Inventory of Existing Chemical SubstancesKECL - Korean Existing and Evaluated Chemical SubstancesPICCS - Philippines Inventory of Chemicals and Chemical SubstancesAICS - Australian Inventory of Chemical Substances

U.S. Federal Regulations

SARA 313Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain anychemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.

Component SARA 313 - Threshold Values %Glycerol

56-81-5 ( 95-100 )-

SARA 311/312 Hazard Categories Acute Health Hazard NoChronic Health Hazard NoFire Hazard NoSudden Release of Pressure Hazard NoReactive Hazard No

Clean Water ActThis product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40CFR 122.42)

Chemical Name CWA - ReportableQuantities

CWA - Toxic Pollutants CWA - Priority Pollutants CWA - HazardousSubstances

Glycerol 56-81-5

- - - -

CERCLAThis material, as supplied, does not contain any substances regulated as hazardous substances under the ComprehensiveEnvironmental Response Compensation and Liability Act (CERCLA) (40 CFR 302) or the Superfund Amendments andReauthorization Act (SARA) (40 CFR 355). There may be specific reporting requirements at the local, regional, or state levelpertaining to releases of this material

Chemical Name Hazardous Substances RQs Extremely Hazardous SubstancesRQs

RQ

Glycerol 56-81-5

- - -

U.S. State Regulations

California Proposition 65This product does not contain any Proposition 65 chemicals.

Chemical Name California Prop. 65Glycerol - 56-81-5 -

U.S. State Right-to-Know Regulations

Chemical Name New Jersey Massachusetts PennsylvaniaGlycerol 56-81-5

X X X

_____________________________________________________________________________________________

Page 6 / 7


U.S. EPA Label Information EPA Pesticide Registration Number Not regulated

16. OTHER INFORMATION

Issuing Date 02-Jun-2010Revision Date 08-Jan-2016Revision NoteNo information availableDisclaimerThe above information is believed to be correct but does not purport to be all-inclusive and shall be used only as a guide.The information in this document is based on the present state of our knowledge and is applicable to the product withregard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. VWRInternational and its Affiliates shall not be held liable for any damage resulting from handling.

End of Safety Data Sheet

_____________________________________________________________________________________________

Page 7 / 7

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Material Safety Data SheetHydrochloric acid, 37% MSDS


Product Name: Hydrochloric acid, 37%

Catalog Codes: SLH1360, SLH2206, SLH3052

CAS#: Mixture.

RTECS: MW4025000

TSCA: TSCA 8(b) inventory: Hydrochloric acid


Synonym: Hydrochloric Acid; Muriatic Acid; HydrochloricAcid 37% N.F, F.C.C., Electronic/Cleanroom grades









Hydrogen chloride 7647-01-0 37

Water 7732-18-5 63

Toxicological Data on Ingredients: Hydrogen chloride: GAS (LC50): Acute: 4701 ppm 0.5 hours [Rat].


Potential Acute Health Effects:Very hazardous in case of skin contact (corrosive, irritant, permeator), of eye contact (irritant, corrosive), of ingestion, . Slightlyhazardous in case of inhalation (lung sensitizer). Non-corrosive for lungs. Liquid or spray mist may produce tissue damageparticularly on mucous membranes of eyes, mouth and respiratory tract. Skin contact may produce burns. Inhalation of thespray mist may produce severe irritation of respiratory tract, characterized by coughing, choking, or shortness of breath.Severe over-exposure can result in death. Inflammation of the eye is characterized by redness, watering, and itching. Skininflammation is characterized by itching, scaling, reddening, or, occasionally, blistering.

Potential Chronic Health Effects:Slightly hazardous in case of skin contact (sensitizer). CARCINOGENIC EFFECTS: Classified 3 (Not classifiable forhuman.) by IARC [Hydrochloric acid]. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available. The substance may be toxic to kidneys, liver, mucous membranes, upper

p. 2

respiratory tract, skin, eyes, Circulatory System, teeth. Repeated or prolonged exposure to the substance can produce targetorgans damage. Repeated or prolonged contact with spray mist may produce chronic eye irritation and severe skin irritation.Repeated or prolonged exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchialinfection. Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in oneor many human organs.


Eye Contact:Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Cold water may be used. Get medical attention immediately.

Skin Contact:In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothingand shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before reuse. Thoroughly cleanshoes before reuse. Get medical attention immediately.












Fire Hazards in Presence of Various Substances: of metals



Special Remarks on Fire Hazards:Non combustible. Calcium carbide reacts with hydrogen chloride gas with incandescence. Uranium phosphide reacts withhydrochloric acid to release spontaneously flammable phosphine. Rubidium acetylene carbides burns with slightly warmhydrochloric acid. Lithium silicide in contact with hydrogen chloride becomes incandescent. When dilute hydrochloric acid isused, gas spontaneously flammable in air is evolved. Magnesium boride treated with concentrated hydrochloric acid producesspontaneously flammble gas. Cesium acetylene carbide burns hydrogen chloride gas. Cesium carbide ignites in contact withhydrochloric acid unless acid is dilute. Reacts with most metals to produce flammable Hydrodgen gas.

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Special Remarks on Explosion Hazards:Hydrogen chloride in contact with the following can cause an explosion, ignition on contact, or other violent/vigorous reaction:Acetic anhydride AgClO + CCl4 Alcohols + hydrogen cyanide, Aluminum Aluminum-titanium alloys (with HCl vapor), 2-Aminoethanol, Ammonium hydroxide, Calcium carbide Ca3P2 Chlorine + dinitroanilines (evolves gas), Chlorosulfonic acid Cesiumcarbide Cesium acetylene carbide, 1,1-Difluoroethylene Ethylene diamine Ethylene imine, Fluorine, HClO4 Hexalithiumdisilicide H2SO4 Metal acetylides or carbides, Magnesium boride, Mercuric sulfate, Oleum, Potassium permanganate,beta-Propiolactone Propylene oxide Rubidium carbide, Rubidium, acetylene carbide Sodium (with aqueous HCl), Sodiumhydroxide Sodium tetraselenium, Sulfonic acid, Tetraselenium tetranitride, U3P4 , Vinyl acetate. Silver perchlorate with carbontetrachloride in the presence of hydrochloric acid produces trichloromethyl perchlorate which detonates at 40 deg. C.



Large Spill:Corrosive liquid. Poisonous liquid. Stop leak if without risk. Absorb with DRY earth, sand or other non-combustible material.Do not get water inside container. Do not touch spilled material. Use water spray curtain to divert vapor drift. Use water sprayto reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Call for assistance on disposal.Neutralize the residue with a dilute solution of sodium carbonate. Be careful that the product is not present at a concentrationlevel above TLV. Check TLV on the MSDS and with local authorities.


Precautions:Keep locked up.. Keep container dry. Do not ingest. Do not breathe gas/fumes/ vapor/spray. Never add water to this product.In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and showthe container or the label. Avoid contact with skin and eyes. Keep away from incompatibles such as oxidizing agents, organicmaterials, metals, alkalis, moisture. May corrode metallic surfaces. Store in a metallic or coated fiberboard drum using a strongpolyethylene inner package.




Personal Protection:Face shield. Full suit. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Boots.


Exposure Limits:CEIL: 5 (ppm) from OSHA (PEL) [United States] CEIL: 7 (mg/m3) from OSHA (PEL) [United States] CEIL: 5 from NIOSHCEIL: 7 (mg/m3) from NIOSH TWA: 1 STEL: 5 (ppm) [United Kingdom (UK)] TWA: 2 STEL: 8 (mg/m3) [United Kingdom(UK)]Consult local authorities for acceptable exposure limits.


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Odor: Pungent. Irritating (Strong.)



Color: Colorless to light yellow.

pH (1% soln/water): Acidic.

Boiling Point: 50.5°C (122.9°F)

Melting Point: -46.2°C (-51.2°F) to -25.4 C



Vapor Pressure: 16 kPa (@ 20°C) average



Odor Threshold: 0.25 to 10 ppm



Dispersion Properties: See solubility in water, diethyl ether.

Solubility: Soluble in cold water, hot water, diethyl ether.




Conditions of Instability: Incompatible materials, water

Incompatibility with various substances:Highly reactive with metals. Reactive with oxidizing agents, organic materials, alkalis, water.

Corrosivity:Extremely corrosive in presence of aluminum, of copper, of stainless steel(304), of stainless steel(316). Non-corrosive inpresence of glass.

Special Remarks on Reactivity:Reacts with water especially when water is added to the product. Absorption of gaseous hydrogen chloride on mercuricsulfate becomes violent @ 125 deg. C. Sodium reacts very violently with gaseous hydrogen chloride. Calcium phosphide andhydrochloric acid undergo very energetic reaction. It reacts with oxidizers releasing chlorine gas. Incompatible with, alkalimetals, carbides, borides, metal oxides, vinyl acetate, acetylides, sulphides, phosphides, cyanides, carbonates. Reacts withmost metals to produce flammable Hydrogen gas. Reacts violently (moderate reaction with heat of evolution) with waterespecially when water is added to the product. Isolate hydrogen chloride from heat, direct, alkalies (reacts vigorously), organicmaterials, and oxidizers (especially nitric acid and chlorates), amines, metals, copper and alloys (e.g. brass), hydroxides,zinc (galvanized materials), lithium silicide (incandescence), sulfuric acid(increase in temperature and pressure) Hydrogenchloride gas is emitted when this product is in contact with sulfuric acid. Adsorption of Hydrochloric Acid onto silicon dioxideresults in exothmeric reaction. Hydrogen chloride causes aldehydes and epoxides to violently polymerize. Hydrogen chlorideor Hydrochloric Acid in contact with the folloiwng can cause explosion or ignition on contact or other violent/vigorous reaction:Acetic anhydride, Alcohols + hydrogen cyanide, Aluminum, Aluminum phosphide, Aluminum-titanium alloys (with HClvapor), 2-Amino ethanol, Ammonium, Ammonium hydroxide, 1,4-Benzoquinone diimine, Calcium acetylide (incandescenceupon warming), Calcium carbide, Calcium phosphide, Carbon tetrachloride + silver perchlorate (produce trichlormethyl

p. 5

perchlorate), Cesium acetylene carbide, Cesium carbide, Cesium telluroacylates, Chlorine + dinitroanilines (evolvesgas), Chloroacetaldehyde oxime, Chlorosulfonic acid, Cyanogen chloride (when catalyzed by HCl), 1,1-Difluoroethylene,Dinitroanilines, Ethylene, Ethylene diamine, Ethyl 2-formylpropionate oxime (when generated by using HCl as a catalyst),

Special Remarks on Corrosivity:Highly corrosive. Incompatible with copper and copper alloys. It attacks nearly all metals (mercury, gold, platinium, tantalum,silver, and certain alloys are exceptions). It is one of the most corrosive of the nonoxidizing acids in contact with copper alloys.No corrosivity data on zinc, steel. Severe Corrosive effect on brass and bronze




Toxicity to Animals:Acute oral toxicity (LD50): 900 mg/kg [Rabbit]. Acute toxicity of the vapor (LC50): 1108 ppm, 1 hours [Mouse]. Acute toxicity ofthe vapor (LC50): 3124 ppm, 1 hours [Rat]. (Hydrochloric Acid)

Chronic Effects on Humans:CARCINOGENIC EFFECTS: Classified 3 (Not classifiable for human.) by IARC [Hydrochloric acid]. May cause damage to thefollowing organs: kidneys, liver, mucous membranes, upper respiratory tract, skin, eyes, Circulatory System, teeth.

Other Toxic Effects on Humans:Very hazardous in case of skin contact (corrosive, irritant, permeator), of ingestion, . Hazardous in case of eye contact(corrosive), of inhalation (lung corrosive).

Special Remarks on Toxicity to Animals:Lowest Published Lethal Doses (LDL/LCL) LDL [Man] -Route: Oral; 2857 ug/kg LCL [Human] - Route: Inhalation; Dose: 1300ppm/30M LCL [Rabbit] - Route: Inhalation; Dose: 4413 ppm/30M

Special Remarks on Chronic Effects on Humans:May cause adverse reproductive effects (fetoxicity). May affect genetic material.

Special Remarks on other Toxic Effects on Humans:Acute Potential Health Effects: Skin: Corrosive. Causes severe skin irritation and burns. Eyes: Corrosive. Causes severeeye irritation/conjuntivitis, burns, corneal necrosis. Inhalation: May be fatal if inhaled. Material is extremely destructive totissue of the mucous membranes and upper respiratory tract. Inhalation of hydrochloric acid fumes produces nose, throat,and larryngeal burning, and irritation, pain and inflammation, coughing, sneezing, choking sensation, hoarseness, laryngealspasms, upper respiratory tract edema, chest pains, as well has headache, and palpitations. Inhalation of high concentrationscan result in corrosive burns, necrosis of bronchial epithelium, constriction of the larynx and bronchi, nasospetal perforation,glottal closure, occur, particularly if exposure is prolonged. May affect the liver. Ingestion: May be fatal if swallowed. Causesirritation and burning, ulceration, or perforation of the gastrointestinal tract and resultant peritonitis, gastric hemorrhage andinfection. Can also cause nausea, vomitting (with "coffee ground" emesis), diarrhea, thirst, difficulty swallowing, salivation,chills, fever, uneasiness, shock, strictures and stenosis (esophogeal, gastric, pyloric). May affect behavior (excitement),the cardiovascular system (weak rapid pulse, tachycardia), respiration (shallow respiration), and urinary system (kidneys-renal failure, nephritis). Acute exposure via inhalation or ingestion can also cause erosion of tooth enamel. Chronic PotentialHealth Effects: Prolonged or repeated inhalation and/or ingestion may affect liver, bleeding of nose and gums, nasal and oralmucosal ulceration, conjunctivitis, respiratory tract (changes in pulmonary function, chronic bronchitis, overt respiratory tractabnormalities), teeth (yellowing of teethand erosion of tooth enamel), kidneys, and behavior (muscle contraction or spasticity).Prolonged or repeated skin contact may cause dermatitis. Prolonged or repeated eye contact with vapor/mist can causeconjunctivitis dyspnea, bronchitis. Chemical pneumonitis and pulmonary edema can also




Products of Biodegradation:

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Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.






DOT Classification: Class 8: Corrosive material

Identification: : Hydrochloric acid, solution UNNA: 1789 PG: II



Federal and State Regulations:Connecticut hazardous material survey.: Hydrochloric acid Illinois toxic substances disclosure to employee act: Hydrochloricacid Illinois chemical safety act: Hydrochloric acid New York release reporting list: Hydrochloric acid Rhode Island RTKhazardous substances: Hydrochloric acid Pennsylvania RTK: Hydrochloric acid Minnesota: Hydrochloric acid MassachusettsRTK: Hydrochloric acid Massachusetts spill list: Hydrochloric acid New Jersey: Hydrochloric acid New Jersey spill list:Hydrochloric acid Louisiana RTK reporting list: Hydrochloric acid Louisiana spill reporting: Hydrochloric acid CaliforniaDirector's List of Hazardous Substances: Hydrochloric acid TSCA 8(b) inventory: Hydrochloric acid TSCA 4(a) proposed testrules: Hydrochloric acid SARA 302/304/311/312 extremely hazardous substances: Hydrochloric acid SARA 313 toxic chemicalnotification and release reporting: Hydrochloric acid CERCLA: Hazardous substances.: Hydrochloric acid: 5000 lbs. (2268 kg)



WHMIS (Canada):CLASS D-2A: Material causing other toxic effects (VERY TOXIC). CLASS E: Corrosive liquid.

DSCL (EEC):R25- Toxic if swallowed. R26- Very toxic by inhalation. R34- Causes burns. S1/2- Keep locked up and out of the reach ofchildren. S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S28- After contactwith skin, wash immediately with plenty of [***] S36/37/39- Wear suitable protective clothing, gloves and eye/face protection.S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

HMIS (U.S.A.):

Health Hazard: 3

Fire Hazard: 0

Reactivity: 1



Health: 3

Flammability: 0

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Reactivity: 1

Specific hazard:

Protective Equipment:Gloves. Full suit. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respiratorwhen ventilation is inadequate. Face shield.


References:-Hawley, G.G.. The Condensed Chemical Dictionary, 11e ed., New York N.Y., Van Nostrand Reinold, 1987. -SAX, N.I.Dangerous Properties of Indutrial Materials. Toronto, Van Nostrand Reinold, 6e ed. 1984. -The Sigma-Aldrich Library ofChemical Safety Data, Edition II. -Guide de la loi et du règlement sur le transport des marchandises dangeureuses au canada.Centre de conformité internatinal Ltée. 1986.


Created: 10/09/2005 05:45 PM

Last Updated: 05/21/2013 12:00 PM


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Material Safety Data SheetKanamycin sulfate MSDS


Product Name: Kanamycin sulfate

Catalog Codes: SLK1033, SLK1111

CAS#: 25389-94-0

RTECS: NZ3225030

TSCA: TSCA 8(b) inventory: Kanamycin sulfate

CI#: Not available.

Synonym:


Chemical Formula: C18H36N4O11.H2SO4







Kanamycin sulfate 25389-94-0 100

Toxicological Data on Ingredients: Kanamycin sulfate LD50: Not available. LC50: Not available.


Potential Acute Health Effects: Hazardous in case of eye contact (irritant), of ingestion, of inhalation.

Potential Chronic Health Effects:Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. CARCINOGENIC EFFECTS:Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available. DEVELOPMENTALTOXICITY: Not available. The substance is toxic to the nervous system. Repeated or prolonged exposure to the substancecan produce target organs damage.


Eye Contact: Check for and remove any contact lenses. Do not use an eye ointment. Seek medical attention.



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Products of Combustion: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), sulfur oxides (SO2,SO3...).










Precautions:Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under afume hood. Ground all equipment containing material. Do not breathe dust. Avoid contact with eyes Wear suitable protectiveclothing In case of insufficient ventilation, wear suitable respiratory equipment If you feel unwell, seek medical attention andshow the label when possible.



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Personal Protection: Splash goggles. Lab coat.




Physical state and appearance: Solid. (Crystalline solid.)




Color: White.



Melting Point: Decomposes.



















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Polymerization: No.


Routes of Entry: Eye contact. Inhalation. Ingestion.


Chronic Effects on Humans: The substance is toxic to the nervous system.

Other Toxic Effects on Humans: Hazardous in case of ingestion, of inhalation.











Waste Disposal:






Federal and State Regulations: TSCA 8(b) inventory: Kanamycin sulfate




DSCL (EEC): R36- Irritating to eyes.

HMIS (U.S.A.):

Health Hazard: 2

p. 5

Fire Hazard: 1

Reactivity: 0

Personal Protection: j


Health: 2

Flammability: 1

Reactivity: 0

Specific hazard:

Protective Equipment:Not applicable. Lab coat. Not applicable. Splash goggles.




Created: 10/10/2005 08:20 PM

Last Updated: 05/21/2013 12:00 PM


Material Safety Data SheetLuria-Bertani (LB) Agar, Miller

1: Chemical Product and Company IdentificationProduct Name : Luria-Bertani (LB) Agar, Miller

Catalog Code : 30620042-1,30620042-2,30620042-3,30620042-4CAS# :

RTECS# : Not AvailableTSCA : Not AvailableCI# : Not AvailableChemical Name : Not Available

Chemical Formula : Not Available

Contact Information : bioWORLD4150 Tuller RoadSuite 228Dublin,OH 43017,USAPhone Number : 614-792-8680Fax Number : 614-792-8685Order Online : http://www.bio-world.com/E-mail : [email protected] Case of a chemical emergency:Contact local hospital For non-emergency assistance:Call 1-800-860-9729

Synonym : Not Available

2: Composition and Information on IngredientsName CAS# % of weightTryptone 91079-40-2 1%Yeast Extract 8013-01-2 0.5%Sodium Chloride 7647-14-5 1%Agar 9002-18-0 1.5%

Toxicological Data : Not Available

3: Hazards IdentificationPotential Acute Health Effects : Not Available

Potentials Chronic Health Effects :

Carcinogenic Effects : Not Available

Mutagenic Effects : Not Available

Teratogenic Effects : Not Available

Developmental Toxicity : Not Available

4: First Aid Measures Eye Contact : In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate

flushing by separating the eyelids with fingers. Call a physician.

Skin Contact : In case of contact, immediately wash skin with soap and copious amounts of water. Call a physician if irritation

persists.

Serious Skin Contact : Not Available

Inhalation : If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Serious Inhalation : Not Available

Page 1

Ingestion : If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Serious Ingestion : Not Available

5: Fire and Explosion DataFlammability of the Product : Not Available

Auto-Ignition Temperature : Not Available

Flash Points : Not Available

Flammable Limits : Not Available

Product of Combustion : Not Available

File Hazards in Presence of Various Substances : Not Available

Explosion Hazards in Presence of Various Substances : Not Available

Fire Fighting Media and Instructions :

SMALL FIRE : Not Available

LARGE FIRE : Not Available

Special Remarks on Fire Hazards : Not Available

Special Remarks on Explosion Hazards : Not Available

6 : Accidental Release MeasuresSmall Spill :

Large Spill : 7: Handling and Storage

Precautions : Avoid inhalation. Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeated exposure.

Storage : Conditions of Storage: Keep tightly closed.

8: Exposure Controls/Personal ProtectionEngineering Controls : Safety shower and eye bath. Mechanical exhaust required.

Personal Protection : Respiratory Protection:dust masks.Hand Protection: Protective gloves. Eye Protection: Chemical safety

goggles.

Personal Protection in Case of a Large Spill : Not Available

Exposure Limits : Not Available

9: Physical and Chemical PropertiesPhysical State and Appearance : light amber agar

Odor : Not Available

Taste : Not Available

Molecular Weight : Not Available

Color : Not Available

PH Value : 7.0

Boiling Point : Not Available

Melting Point : Not Available

Critical Temperature : Not Available

Specific Gravity : Not Available

Page 2

Vapour Pressure : Not Available

Vapor Density : Not Available

Volatility : Not Available

Odor Threshold:Not Available

Water/Oil Dist. Coeff : Not Available

Ionicity(in Water) : Not Available

Dispersion Properties : Not Available

Solubility : Soluble in boiling water

10: Stability and Reactivity DataStability : Stable

Instability Temperature :

Conditions of Instability :

Incompatibility with various substances : Strong oxidizers, moisture

Corrosivity : Not Available

Special Remarks on Reactivity : Not Available

Special Remarks on Corrosivity : Not Available

Polymerization : will not occur

11:Toxicological InformationRoutes of Entry : Skin contact, eye contact, inhalation, ingestion

Toxicity to Animals : Not AvailableNot Available

Chronic Effects on Humans : Not Available

Other Toxic Effects on Humans : Not Available

Special Remarks on Toxicity to Animals : Not Available

Special Remarks on Chronic Effects on Humans : Not Available

Special Remarks on other Toxic Effects on Humans : Not Available

12: Ecological InformationEcotoxicity : Not Available

BOD5 and COD : Not Available

Product of Biodegradation : Not Available

Toxicity of the Products of Biodegradation : Not Available

Special Remarks on the Products of Biodegradation : Not Available

13: Disposal ConsiderationsWaste Disposal : Waste must be disposed of in accordance with federal, state and local environmental control regulations.

14: Transport InformationDOT Classification : Not a DOT controlled material.

Identification : Not available.

Special Provisions for Transport : Not available.


Page 3

Federal and State Regulations : Not available.

Other Regulations : Not available.

Other Classifications : Not available.

WHMIS(Canada) : Not available.

DSCL(EEC) : Not available.

HMIS(U.S.A) :

Health Hazard : 0

Fire Hazard : 0

Reactivity : 0

Personal Protection :

National Fire Protection Association (U.S.A) :

Health : 0

Flammability : 0

Reactivity : 0

Specific hazard :

Protective Equipment : Respiratory Protection: Use respirators and dust masks.Hand Protection:Protective gloves.Eye

Protection: Chemical safety goggles

16: Other InformationReferences : Not available.

Other Special Considerations : Created : 10/11/2011 12:33:00 PM Last Updated : 12/29/2011 10:41:08 AM

DisclaimerThis product is offered by for research, laboratory or further manufacturing use. Not for human use or consumption.The information above is believed to be accurate and represents the best information currently available to us. However,we make no warranty ofmerchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Usersshould make their own investigations to determine the suitability of the information for their particular purposes.In no event shall be liable for anyclaims, losses, or damages of any third party or for lost profits or any special, indirect,incidental,consequential or exemplary damages, howsoeverarising, even if has been advised of the possibility of such damages.

Page 4

_____________________________________________________________________________________________

SAFETY DATA SHEET

_____________________________________________________________________________________________

Identification of the substance/preparation

24 hour Emergency Response (Transport): 866-536-0631301-431-8585Outside of the U.S. +1-301-431-8585

Product code

For research use only Not intended for human or animal diagnostic or therapeutic uses

Revision Date

A1374401

Product name M9 Minimal Salts (2x)

Company/Undertaking Identification

Page 1 / 6

1. Ident i f ic at ion of t he subst anc e/m ix t ure and of t he c om pany/under t ak ing

04-Oct-2011


www.lifetechnologies.com

Product code

INVITROGEN CORPORATION5250 MAINWAY DRIVEBURLINGTON, ONTCANADA L7L 6A4800/263-6236

A1374401

Life Technologies5791 VAN ALLEN WAYPO BOX 6482CARLSBAD, CA 92008+1 760 603 7200

Aggravated MedicalConditions

No known effects under normal use conditions

not hazardous

HMIS

Principle Routes of Exposure/Potential Health effects

GHS - Classification

Eyes May cause eye irritation with susceptible persons.

Signal Word not hazardous

Skin May cause skin irritation in susceptible persons.Inhalation May be harmful by inhalation.Ingestion May be harmful if swallowed.

Specific effectscarcinogenic effects none.mutagenic effects none.

_____________________________________________________________________________________________

2. Hazards ident i f ic at ion

Reproductive toxicity none.Sensitization none

Health Hazard

Revision Date

not hazardous


Flammability

Page 2 / 6

0

Physical Hazards

04-Oct-2011


Product code

Health 0

A1374401

Reactivity 0

4. First a id measures

Methods for cleaning up

Exposure limits

Soak up with inert absorbent material

Ingestion

Exposure limits We are not aware of any national exposure limit

Never give anything by mouth to an unconscious person. If symptoms persist, calla physician. Do not induce vomiting without medical advice.


Engineering measures Ensure adequate ventilation, especially in confined areas

Suitable extinguishing media Water spray. Carbon dioxide (CO2). Foam. Dry chemical.

Skin contact

Personal protective equipment

Inhalation

Prevent further leakage or spillage if safe to do so

Special protective equipment for firefighters Wear self-contained breathing apparatus and protectivesuit

Move to fresh air. If symptoms persist, call a physician. If not breathing, giveartificial respiration.

Rinse with plenty of water. If symptoms arise, call a physician.

See Section 12 for additional information.

Notes to physician

_____________________________________________________________________________________________

7. Handling and storage

Treat symptomatically

6. Accidental re lease measures

Handling Always wear reccommended Personal Protective Equipment. No special handlingadvice required.

Eye contact

Storage Keep in a dry, cool and well-ventilated place.

Revision DateProduct name M9 Minimal Salts (2x)

Rinse immediately with plenty of water, also under the eyelids, for at least 15minutes. If symptoms persist, call a physician.

Page 3 / 6

Personal precautions

8. Exposure controls/personal protect ion

04-Oct-2011

Use personal protective equipment

5. Fire-fight ing measures


The product contains no substances which at their given concentration, are considered to be hazardous to health. Werecommend handling all chemicals with caution.

Product code

3. Com posi t ion/in form at ion on ingredient s

A1374401

polymerization Hazardous polymerisation does not occur.

Skin and body protection Lightweight protective clothing

11. Toxicological information

General Information

Acute toxicity

Respiratory protection

Form liquid

Acute toxicity not hazardous.

Hygiene measures

Appearance No information available


Handle in accordance with good industrial hygiene and safety practice

Eyes May cause eye irritation with susceptible persons.

Odor

Skin May cause skin irritation in susceptible persons.

No information available

Inhalation May be harmful by inhalation.Ingestion May be harmful if swallowed.

Hand protection Impervious gloves

carcinogenic effects none.

Environmental exposurecontrols

mutagenic effects none.

Prevent product from entering drains

Reproductive toxicity none.

Oxidizing properties No information available

Sensitization none.

Water solubility soluble

In case of insufficient ventilation wear suitable respiratory equipment

10. Stability and react ivity

Eye protection Safety glasses with side-shields

Stability Stable under normal conditions.

_____________________________________________________________________________________________

9. Physical and chemical propert ies

Materials to avoid No dangerous reaction known under conditions of normal use.Hazardous decompositionproducts

None under normal use.

°F no data available°F no data available


Page 4 / 6

°C no data available°F no data available°C no data available

04-Oct-2011

Flash point


Autoignition temperature

°F no data available

Product code

°C no data available°C no data available

Melting point/range

A1374401

Boiling Point/Range

Subsidiary Class none

No known effects under normal use conditions.

Packing group none

Mobility

UN-No None


13. Disposal considerat ions

12. Ecological information

_____________________________________________________________________________________________

Biodegradation Inherently biodegradable.

Dispose of in accordance with local regulations

Bioaccumulation Does not bioaccumulate.

14. Transport information


Page 5 / 6

Aggravated MedicalConditions

IATA

04-Oct-2011


Proper shipping name

Product code

Not classified as dangerous in the meaning of transport regulations

Ecotoxicity effects No information available

A1374401

Hazard class none

The above information was acquired by diligent search and/or investigation and the recommendations are based onprudent application of professional judgment. The information shall not be taken as being all inclusive and is to beused only as a guide. All materials and mixtures may present unknown hazards and should be used with caution.Since the Company cannot control the actual methods, volumes, or conditions of use, the Company shall not be heldliable for any damages or losses resulting from the handling or from contact with the product as described herein.THE INFORMATION IN THIS MSDS DOES NOT CONSTITUTE A WARRANTY, EXPRESSED OR IMPLIED,INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULARPURPOSE.

16. Ot her in form at ion


For research use only. Not intended for human or animal diagnostic or therapeutic uses.

Reason for Revision (M)SDS sections updated.

SARA 313 This product is not regulated by SARA.

_____________________________________________________________________________________________

WHMIS hazard class: Non-controlled

This product has been classified according to the hazard criteria of the CPR and the MSDS contains all of the information required by the CPR


Revision Date


Product name M9 Minimal Salts (2x)Page 6 / 604-Oct-2011

15. Regulat ory in form at ion

Clean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61) This product does not contains HAPs.


Product code

California Proposition 65 This product does not contain chemicals listed under Proposition 65

A1374401

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E

Material Safety Data SheetMagnesium chloride hexahydrate MSDS


Product Name: Magnesium chloride hexahydrate

Catalog Codes: SLM3697, SLM2926, SLM4306

CAS#: 7791-18-6

RTECS: OM2975000

TSCA: TSCA 8(b) inventory: Magnesium chloridehexahydrate


Synonym:

Chemical Name: Magnesium dichloride hexahydrate

Chemical Formula: Mg-Cl2.6H2O







Magnesium chloride hexahydrate 7791-18-6 100



Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant, permeator), of eye contact (irritant), ofingestion, of inhalation.

Potential Chronic Health Effects:CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available. The substance is toxic to cardiovascular system, upper respiratory tract.Repeated or prolonged exposure to the substance can produce target organs damage.



p. 2

Skin Contact:After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with runningwater and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cold water may be used.Cover the irritated skin with an emollient. If irritation persists, seek medical attention.















Special Remarks on Fire Hazards: Store under nitrogen. When heated to decomposition it emits toxic fumes.






Precautions:Do not ingest. Do not breathe dust. If ingested, seek medical advice immediately and show the container or the label. Keepaway from incompatibles such as oxidizing agents.

Storage:No specific storage is required. Use shelves or cabinets sturdy enough to bear the weight of the chemicals. Be sure that it isnot necessary to strain to reach materials, and that shelves are not overloaded.

p. 3







Physical state and appearance: Solid. (Deliquescent crystals solid.)





pH (1% soln/water): 7 [Neutral.]











Dispersion Properties: See solubility in water, methanol.

Solubility:Easily soluble in cold water, hot water, methanol. Insoluble in diethyl ether, n-octanol.





Incompatibility with various substances:

p. 4

Reactive with oxidizing agents. Non-reactive with moisture.




Polymerization: No.



Toxicity to Animals: Acute oral toxicity (LD50): 8100 mg/kg [Rat.].

Chronic Effects on Humans: The substance is toxic to cardiovascular system, upper respiratory tract.

Other Toxic Effects on Humans: Slightly hazardous in case of skin contact (irritant, permeator), of ingestion, of inhalation.



Special Remarks on other Toxic Effects on Humans: Material is irritating to mucous membranes and upper respiratorytract.








Waste Disposal:






Federal and State Regulations:California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer,birth defects or other reproductive harm, which would require a warning under the statute: Magnesium chloride hexahydrateCalifornia prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer

p. 5

which would require a warning under the statute: Magnesium chloride hexahydrate TSCA 8(b) inventory: Magnesium chloridehexahydrate





HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 0

Reactivity: 0



Health: 2

Flammability: 0

Reactivity: 0

Specific hazard:



References:-Hawley, G.G.. The Condensed Chemical Dictionary, 11e ed., New York N.Y., Van Nostrand Reinold, 1987. -SAX, N.I.Dangerous Properties of Indutrial Materials. Toronto, Van Nostrand Reinold, 6e ed. 1984. -The Sigma-Aldrich Library ofChemical Safety Data, Edition II.


Created: 10/10/2005 08:21 PM

Last Updated: 05/21/2013 12:00 PM


p. 1

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Material Safety Data SheetMagnesium chloride hexahydrate MSDS


Product Name: Magnesium chloride hexahydrate

Catalog Codes: SLM3697, SLM2926, SLM4306

CAS#: 7791-18-6

RTECS: OM2975000

TSCA: TSCA 8(b) inventory: Magnesium chloridehexahydrate


Synonym:

Chemical Name: Magnesium dichloride hexahydrate

Chemical Formula: Mg-Cl2.6H2O







Magnesium chloride hexahydrate 7791-18-6 100




Potential Chronic Health Effects:CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available. The substance is toxic to cardiovascular system, upper respiratory tract.Repeated or prolonged exposure to the substance can produce target organs damage.



p. 2

Skin Contact:After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with runningwater and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cold water may be used.Cover the irritated skin with an emollient. If irritation persists, seek medical attention.















Special Remarks on Fire Hazards: Store under nitrogen. When heated to decomposition it emits toxic fumes.






Precautions:Do not ingest. Do not breathe dust. If ingested, seek medical advice immediately and show the container or the label. Keepaway from incompatibles such as oxidizing agents.


p. 3







Physical state and appearance: Solid. (Deliquescent crystals solid.)
















Dispersion Properties: See solubility in water, methanol.

Solubility:Easily soluble in cold water, hot water, methanol. Insoluble in diethyl ether, n-octanol.





Incompatibility with various substances:

p. 4

Reactive with oxidizing agents. Non-reactive with moisture.




Polymerization: No.



Toxicity to Animals: Acute oral toxicity (LD50): 8100 mg/kg [Rat.].

Chronic Effects on Humans: The substance is toxic to cardiovascular system, upper respiratory tract.




Special Remarks on other Toxic Effects on Humans: Material is irritating to mucous membranes and upper respiratorytract.








Waste Disposal:






Federal and State Regulations:California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer,birth defects or other reproductive harm, which would require a warning under the statute: Magnesium chloride hexahydrateCalifornia prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer

p. 5

which would require a warning under the statute: Magnesium chloride hexahydrate TSCA 8(b) inventory: Magnesium chloridehexahydrate





HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 0

Reactivity: 0



Health: 2

Flammability: 0

Reactivity: 0

Specific hazard:





Created: 10/10/2005 08:21 PM

Last Updated: 05/21/2013 12:00 PM


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A

Material Safety Data SheetMagnesium Sulfate - 2.25% MSDS


Product Name: Magnesium Sulfate - 2.25%

Catalog Codes: SLM1288

CAS#: Mixture.


TSCA: TSCA 8(b) inventory: Magnesium sulfateheptahydrate; Water

CI#: Not available.

Synonym:









Magnesium sulfate heptahydrate 10034-99-8 2.25

Water 7732-18-5 97.8



Potential Acute Health Effects: Slightly hazardous in case of ingestion. Non-corrosive for skin. Non-sensitizer for skin. Non-permeator by skin.Potential Chronic Health Effects:Non-corrosive for skin. Non-irritant for skin. Non-sensitizer for skin. Non-permeator by skin. Non-irritating to the eyes.Non-hazardous in case of ingestion. Non-hazardous in case of inhalation. CARCINOGENIC EFFECTS: Not available.MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Notavailable.



p. 2




















Large Spill:Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by spreading wateron the contaminated surface and allow to evacuate through the sanitary system.


Precautions: No specific safety phrase has been found applicable for this product.



Engineering Controls:

p. 3

Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respectivethreshold limit value.














Specific Gravity: Weighted average: 1.01 (Water = 1)

Vapor Pressure: The highest known value is 17.535 mm of Hg (@ 20°C) (Water).
















Polymerization: No.

p. 4





Other Toxic Effects on Humans:Slightly hazardous in case of ingestion. Non-corrosive for skin. Non-sensitizer for skin. Non-permeator by skin.


Special Remarks on Chronic Effects on Humans: Passes through the placental barrier in human. (Magnesium sulfateheptahydrate)









Waste Disposal:






Federal and State Regulations: TSCA 8(b) inventory: Magnesium sulfate heptahydrate; Water

Other Regulations: Not available. or of its ingredients




HMIS (U.S.A.):

Health Hazard: 0

p. 5

Fire Hazard: 0

Reactivity: 0



Health: 0

Flammability: 0

Reactivity: 0

Specific hazard:

Protective Equipment:Not applicable. Lab coat. Not applicable. Safety glasses.




Created: 10/10/2005 10:40 AM

Last Updated: 05/21/2013 12:00 PM


Kit Components07/08/2015

Product code Description

1708353 EZ Load™ Molecular Ruler 100 bp PCR Kit1708353EDU

Components:9703448 Nucleic Acid Sample Loading Buffer, 5X9703457 EZ Load™ 100 bp Molecular Ruler

/7Safety Data Sheet


41.1.0

* 1 Identification· Product identifier· Trade name: Nucleic Acid Sample Loading Buffer, 5X· Catalog or product number: 9703448· Relevant identified uses of the substance or mixture and uses advised againstNo further relevant information available.

· Application of the substance / the mixture Laboratory chemicals






* 3 Composition/information on ingredients· Chemical characterization: Mixtures· Description: Mixture of the substances listed below with non-hazardous additions.· Listing of dangerous and non-hazardous components:

56-81-5 glycerol 20-35%7732-18-5 water 50-100%

· Additional information For the wording of the listed risk phrases refer to section 15. US

(Contd. on page 2)

/7Safety Data Sheet


Trade name: Nucleic Acid Sample Loading Buffer, 5X

(Contd. of page 1)

41.1.0




* 6 Accidental release measures· Personal precautions, protective equipment and emergency procedures Wear protective clothing.· Environmental precautions:Dilute with plenty of water.Do not allow to enter sewers/ surface or ground water.

· Methods and material for containment and cleaning up:Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).



· Conditions for safe storage, including any incompatibilities· Storage· Requirements to be met by storerooms and receptacles: According to product specification· Information about storage in one common storage facility: Not required.· Further information about storage conditions: None.


/7Safety Data Sheet



(Contd. of page 2)

41.1.0

· Specific end use(s) No further relevant information available.


· Control parameters· Components with limit values that require monitoring at the workplace:56-81-5 glycerolPEL () 15* 5** mg/m³

*total dust **respirable fractionTLV () 10* ppm

*Mist· Additional information: The lists that were valid during the creation were used as basis.


· Eye protection: Safety glasses



· Odor: Odorless· Odour threshold: Not determined.

· pH-value: Not determined.




· Ignition temperature: 400 °C

· Decomposition temperature: Not determined.

· Auto igniting: Product is not selfigniting.(Contd. on page 4)

US

/7Safety Data Sheet



(Contd. of page 3)

41.1.0


· Explosion limits:Lower: 0.9 Vol %Upper: Not determined.


· Density: Not determined· Relative density Not determined.· Vapour density Not determined.· Evaporation rate Not determined.





Solids content: 1.2 %· Other information No further relevant information available.

* 10 Stability and reactivity· Reactivity No further relevant information available.· Chemical stability· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.· Possibility of hazardous reactions No dangerous reactions known· Conditions to avoid No further relevant information available.· Incompatible materials: No further relevant information available.· Hazardous decomposition products: No dangerous decomposition products known

* 11 Toxicological information· Information on toxicological effects· Acute toxicity:· Primary irritant effect:· on the skin: No irritant effect.· on the eye: No irritant effect.· Sensitization: No sensitizing effects known.· Additional toxicological information:The product is not subject to classification according to the calculation method of the General EU Classification Guidelinesfor Preparations as issued in the latest version:


/7Safety Data Sheet



(Contd. of page 4)

41.1.0

When used and handled according to specifications, the product does not have any harmful effects according to ourexperience and the information provided to us.

· Carcinogenic categories· IARC (International Agency for Research on Cancer)None of the ingredients is listed.




* 12 Ecological information· Toxicity· Aquatic toxicity: No further relevant information available.· Persistence and degradability No further relevant information available.· Behavior in environmental systems:· Bioaccumulative potential No further relevant information available.· Mobility in soil No further relevant information available.· Additional ecological information:· General notes:Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water.Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.

· Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.· Other adverse effects No further relevant information available.






/7Safety Data Sheet



(Contd. of page 5)

41.1.0







· UN "Model Regulation": -


· Section 313 (40CFR372.65):None of the ingredients is listed.

· TSCA (Toxic Substances Control Act):56-81-5 glycerol77-86-1 Tris(hydroxymethyl)aminomethane

2650-17-1 Xylene cyanole FF60-00-4 ethylenediaminetetraacetic acid

7732-18-5 water


· TLV (Threshold Limit Value established by ACGIH)None of the ingredients is listed.

· MAK (German Maximum Workplace Concentration)None of the ingredients is listed.



/7Safety Data Sheet



(Contd. of page 6)

41.1.0


Class Share in %NK 20-35

· Water hazard class: Water hazard class 1 (Self-assessment): slightly hazardous for water.· Chemical safety assessment: A Chemical Safety Assessment has not been carried out.




ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage ofDangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsDOT: US Department of TransportationIATA: International Air Transport AssociationACGIH: American Conference of Governmental Industrial HygienistsEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)PBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very Bioaccumulative


/7Safety Data Sheet


41.1.0

* 1 Identification· Product identifier· Trade name: EZ Load™ 100 bp Molecular Ruler· Catalog or product number: 9703457, 9703457S, 9703458· Relevant identified uses of the substance or mixture and uses advised againstNo further relevant information available.

· Application of the substance / the mixture Laboratory chemicals






* 3 Composition/information on ingredients· Chemical characterization: Mixtures· Description: Mixture of the substances listed below with non-hazardous additions.· Listing of dangerous and non-hazardous components:

56-81-5 glycerol 5-10%77-86-1 Tris(hydroxymethyl)aminomethane 0.1-1.0%

7732-18-5 water 50-100%· Additional information For the wording of the listed risk phrases refer to section 15.

US

(Contd. on page 2)

/7Safety Data Sheet


Trade name: EZ Load™ 100 bp Molecular Ruler

(Contd. of page 1)

41.1.0




* 6 Accidental release measures· Personal precautions, protective equipment and emergency procedures Wear protective clothing.· Environmental precautions: Dilute with plenty of water.· Methods and material for containment and cleaning up:Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).



· Conditions for safe storage, including any incompatibilities· Storage· Requirements to be met by storerooms and receptacles: According to product specification· Information about storage in one common storage facility: Not required.· Further information about storage conditions: None.· Specific end use(s) No further relevant information available.

US

(Contd. on page 3)

/7Safety Data Sheet



(Contd. of page 2)

41.1.0


· Control parameters· Components with limit values that require monitoring at the workplace:56-81-5 glycerolPEL () 15* 5** mg/m³

*total dust **respirable fractionTLV () 10* ppm

*Mist· Additional information: The lists that were valid during the creation were used as basis.


· Eye protection: Safety glasses



· Odor: Odorless· Odour threshold: Not determined.

· pH-value at 20 °C: 8




· Ignition temperature: 400 °C

· Decomposition temperature: Not determined.

· Auto igniting: Product is not selfigniting.


· Explosion limits:Lower: Not determined.


/7Safety Data Sheet



(Contd. of page 3)

41.1.0

Upper: Not determined.


· Density: Not determined· Relative density Not determined.· Vapour density Not determined.· Evaporation rate Not determined.





Solids content: 0.4 %· Other information No further relevant information available.

* 10 Stability and reactivity· Reactivity No further relevant information available.· Chemical stability· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.· Possibility of hazardous reactions No dangerous reactions known· Conditions to avoid No further relevant information available.· Incompatible materials: No further relevant information available.· Hazardous decomposition products: No dangerous decomposition products known

* 11 Toxicological information· Information on toxicological effects· Acute toxicity:· Primary irritant effect:· on the skin: No irritant effect.· on the eye: No irritant effect.· Sensitization: No sensitizing effects known.· Additional toxicological information:The product is not subject to classification according to the calculation method of the General EU Classification Guidelinesfor Preparations as issued in the latest version:When used and handled according to specifications, the product does not have any harmful effects according to ourexperience and the information provided to us.


/7Safety Data Sheet



(Contd. of page 4)

41.1.0

· Carcinogenic categories· IARC (International Agency for Research on Cancer)None of the ingredients is listed.




* 12 Ecological information· Toxicity· Aquatic toxicity: No further relevant information available.· Persistence and degradability No further relevant information available.· Behavior in environmental systems:· Bioaccumulative potential No further relevant information available.· Mobility in soil No further relevant information available.· Additional ecological information:· General notes: Generally not hazardous for water.· Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.· Other adverse effects No further relevant information available.







/7Safety Data Sheet



(Contd. of page 5)

41.1.0






· UN "Model Regulation": -


· Section 313 (40CFR372.65):None of the ingredients is listed.

· TSCA (Toxic Substances Control Act):56-81-5 glycerol77-86-1 Tris(hydroxymethyl)aminomethane

2650-17-1 Xylene cyanole FF115-39-9 tetrabromophenol blue

7732-18-5 water


· TLV (Threshold Limit Value established by ACGIH)None of the ingredients is listed.

· MAK (German Maximum Workplace Concentration)None of the ingredients is listed.



Class Share in %NK 5-10

· Water hazard class: Generally not hazardous for water.(Contd. on page 7)

US

/7Safety Data Sheet



(Contd. of page 6)

41.1.0

· Chemical safety assessment: A Chemical Safety Assessment has not been carried out.




ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International Carriage ofDangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsDOT: US Department of TransportationIATA: International Air Transport AssociationACGIH: American Conference of Governmental Industrial HygienistsEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)PBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very Bioaccumulative


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Material Safety Data SheetPolyethylene glycol 8000 MSDS


Product Name: Polyethylene glycol 8000

Catalog Codes: SLP1393

CAS#: 25322-68-3

RTECS: TQ4105000

TSCA: TSCA 8(b) inventory: Polyethylene glycol 8000

CI#: Not available.

Synonym: PEG-150;

Chemical Name: Polyethylene Glycol 8000

Chemical Formula: H(OCH2CH2)nOH







Polyethylene glycol 8000 25322-68-3 100

Toxicological Data on Ingredients: Polyethylene glycol 8000: ORAL (LD50): Acute: >50000 mg/kg [Rat]. DERMAL(LD50): Acute: >20000 mg/kg [Rabbit].






p. 2










Flash Points: OPEN CUP: 268.33°C (515°F) (Cleveland.).



Fire Hazards in Presence of Various Substances: Slightly flammable to flammable in presence of heat.







Large Spill:Absorb with an inert material and put the spilled material in an appropriate waste disposal. Finish cleaning by spreading wateron the contaminated surface and allow to evacuate through the sanitary system. Be careful that the product is not present at aconcentration level above TLV. Check TLV on the MSDS and with local authorities.


Precautions:Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under afume hood. Ground all equipment containing material. Do not ingest. Do not breathe gas/fumes/ vapor/spray. Wear suitable

p. 3

protective clothing. If ingested, seek medical advice immediately and show the container or the label. Keep away fromincompatibles such as oxidizing agents.

Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 23°C (73.4°F).



Personal Protection:Safety glasses. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.


Exposure Limits:TWA: 10 (mg/m3) from AIHA Consult local authorities for acceptable exposure limits.


Physical state and appearance: Liquid. (Viscous)



Molecular Weight: 8000 g/mole

Color: Clear






Vapor Pressure: Not available.







Solubility: Soluble in cold water, hot water.



p. 4


Conditions of Instability: Incompatible materials (strong oxiders), dust generation, excess heat



Special Remarks on Reactivity: Slightly Hygroscopic




Routes of Entry: Absorbed through skin. Eye contact.

Toxicity to Animals:Acute oral toxicity (LD50): >50000 mg/kg [Rat]. Acute dermal toxicity (LD50): >20000 mg/kg [Rabbit].







Ecotoxicity: Ecotoxicity in water (LC50): >5000 mg/l 24 hours [Goldfish].






Waste Disposal:






Federal and State Regulations:

p. 5

Minnesota: Polyethylene glycol 8000 TSCA 8(b) inventory: Polyethylene glycol 8000




DSCL (EEC):R20/22- Harmful by inhalation and if swallowed. S24/25- Avoid contact with skin and eyes.

HMIS (U.S.A.):

Health Hazard: 1

Fire Hazard: 1

Reactivity: 0

Personal Protection: g


Health: 0

Flammability: 1

Reactivity: 0

Specific hazard:

Protective Equipment:Gloves. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Safety glasses.




Created: 10/10/2005 11:33 AM

Last Updated: 05/21/2013 12:00 PM


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Material Safety Data SheetPotassium chloride MSDS


Product Name: Potassium chloride

Catalog Codes: SLP3334, SLP5143, SLP2317, SLP4126

CAS#: 7447-40-7

RTECS: TS8050000

TSCA: TSCA 8(b) inventory: Potassium chloride

CI#: Not available.

Synonym:

Chemical Name: Potassium Chloride

Chemical Formula: KCl







Potassium chloride 7447-40-7 100

Toxicological Data on Ingredients: Potassium chloride: ORAL (LD50): Acute: 2500 mg/kg [Guinea pig]. 2600 mg/kg [Rat].1500 mg/kg [Mouse].


Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, ofinhalation.

Potential Chronic Health Effects:CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic forbacteria and/or yeast. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available. The substancemay be toxic to blood, cardiovascular system. Repeated or prolonged exposure to the substance can produce target organsdamage.


Eye Contact:

p. 2

Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Cold water may be used. Get medical attention.














Explosion Hazards in Presence of Various Substances:Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product inpresence of static discharge: Not available. Slightly explosive in presence of oxidizing materials.



Special Remarks on Explosion Hazards: May result in explosion with potassium permanganate and sulfuric acid.





Precautions:Do not ingest. Do not breathe dust. If ingested, seek medical advice immediately and show the container or the label. Keepaway from incompatibles such as oxidizing agents, acids, moisture.

Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area. Hygroscopic

p. 3








Odor: Odorless.

Taste: Saline. (Strong.)


Color: White.


Boiling Point: 1420°C (2588°F)

Melting Point: 770°C (1418°F)










Solubility:Soluble in cold water, hot water. Very slightly soluble in methanol, n-octanol.




Conditions of Instability: Incompatible materials

Incompatibility with various substances: Reactive with oxidizing agents, acids.

p. 4


Special Remarks on Reactivity:Hygroscopic. Incompatible with KMnO4, H2SO4, BrF3, and BrCl3. May react violently with BrF3.




Routes of Entry: Inhalation. Ingestion.

Toxicity to Animals: Acute oral toxicity (LD50): 1500 mg/kg [Mouse].

Chronic Effects on Humans: May cause damage to the following organs: blood, cardiovascular system.



Special Remarks on Chronic Effects on Humans:May affect genetic material. Passes through the placental barrier in animal.

Special Remarks on other Toxic Effects on Humans:Actute Potential Health Effects: Skin: May cause skin irritation Eye: Dust may cause eye irritation. Inhalation: Dust may causerespiratory tract irritation. Low hazard for usual industrial handling Ingestion: May affect behavior (coma, change in motoractivity, listlessness, vertigo, mental confusion, paresthesias, general weakness, flaccid paralysis), metabolism, blood (changein clotting factor, electrolytic imbalance), cardiovascular (hypotension, circulatory disturbances, cardiac arrhythmias, heartblock), and respiratory, gastrointestinal (irritation of GI tract, nausea, vomiting, diarrhea, abdominal discomfort, purging), andurinary(impairment of renal function) systems. Acute potassium intoxication by mouth is rare because large single dosesusually induce vomiting, and because in the absence of pre-existing kidney damage potassium is rapidly excreted. Maximalnontoxic oral dose of KCl in man varies from 0.2g to 1 g of potassium/kg/day depending upon efficiency of individual excretorymechanism; lower doses sometimes cause impairment of renal function as shown by reduced inulin, and urea clearance.Chronic Potential Health Effects: May affect blood and cardiovascular system.












p. 5



Federal and State Regulations: TSCA 8(b) inventory: Potassium chloride




DSCL (EEC):R36- Irritating to eyes. S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39-Wear eye/face protection.

HMIS (U.S.A.):

Health Hazard: 1

Fire Hazard: 0

Reactivity: 0



Health: 1

Flammability: 0

Reactivity: 0

Specific hazard:





Created: 10/10/2005 08:49 PM

Last Updated: 05/21/2013 12:00 PM


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Material Safety Data SheetPotassium phosphate dibasic MSDS


Product Name: Potassium phosphate dibasic

Catalog Codes: SLP1810, SLP2605

CAS#: 7758-11-4


TSCA: TSCA 8(b) inventory: Potassium phosphate dibasic

CI#: Not available.

Synonym: Dipotassium Phosphate

Chemical Name: Potassium Phosphate, dibasic

Chemical Formula: K2HPO4







Potassium phosphate dibasic 7758-11-4 100

Toxicological Data on Ingredients: Potassium phosphate dibasic LD50: Not available. LC50: Not available.


Potential Acute Health Effects:Hazardous in case of eye contact (irritant), of ingestion. Slightly hazardous in case of skin contact (irritant), of inhalation.



Eye Contact:Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Cold water may be used. Get medical attention.

Skin Contact:

p. 2

Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold watermay be used.





















Precautions:Do not breathe dust. Avoid contact with eyes. Wear suitable protective clothing. If you feel unwell, seek medical attention andshow the label when possible. Keep away from incompatibles such as oxidizing agents.

Storage:Hygroscopic Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 23°C (73.4°F).

p. 3



Personal Protection:Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.








Color: White.

pH (1% soln/water): 8.8[Basic.]


Melting Point: Decomposition temperature: >465°C (869°F)










Solubility:Easily soluble in cold water, hot water. Slightly soluble in alcohol




Conditions of Instability: Moisture, Incompatible materials.


p. 4


Special Remarks on Reactivity: Hygroscopic.








Special Remarks on Toxicity to Animals:


Special Remarks on other Toxic Effects on Humans:Acute Potential Health Effects: Skin: Causes mild skin irritation. There is no significant skin irritation hazard for low level(usual) industrial handling or exposure Eyes: Causes eye irritation. Inhalation: Causes respiratory tract and mucous membraneirritation. There is no significant inhalation hazard for low level (usual) industrial handling or exposure. Ingestion: Phosphatesare toxic because of their abillity to sequester calcium, but they are slowly and incompletey absorbed when ingested, andseldom result in systemic effects. Furthermore, acute potassium poisoning by mouth is rare because large single dosesusually induce vomiting and because in the absence of pre-existing kidney damage, potassium is rapidly excreted. However,such effects have occured. Symptoms may include gastrointestinal tract irritation (gastroenteritis) with nausea, vomiting,abdominal discomfort, diarrhea. May affect behavior/central nervous system(somnolence, listlessness, mental confusion,convulsions), metabolism (anorexia), cardiovascular system (fall of blood pressure, cardiac arrythmias, heart block), kidneys(polyuria, polydipsia). May cause mineral imbalance and affect osmotic pressure of body fluids. Other clinical signs andsymptoms of oral overdosage may include: paresthesias of the extremities, weakness or heaviness of the legs, flaccidparalysis, cold skin, gray pallor.











p. 5




Federal and State Regulations: TSCA 8(b) inventory: Potassium phosphate dibasic




DSCL (EEC):R36- Irritating to eyes. S24/25- Avoid contact with skin and eyes.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 0

Reactivity: 0



Health: 2

Flammability: 0

Reactivity: 0

Specific hazard:

Protective Equipment:Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Splash goggles.




Created: 10/09/2005 06:10 PM

Last Updated: 05/21/2013 12:00 PM


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Material Safety Data SheetPotassium phosphate monobasic MSDS


Product Name: Potassium phosphate monobasic

Catalog Codes: SLP2023, SLP2824

CAS#: 7778-77-0

RTECS: TC6615500

TSCA: TSCA 8(b) inventory: Potassium phosphatemonobasic

CI#: Not available.

Synonym: Monopotassium Phosphate; PotassiumDihydrogen Phosphate; Phosphoric Acid, Monopotassiumsalt

Chemical Name: Potassium Phosphate Monobasic

Chemical Formula: KH2PO4







Potassium phosphate monobasic 7778-77-0 100



Potential Acute Health Effects:Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Slightly hazardous in case ofskin contact (permeator).



Eye Contact:

p. 2























Precautions:

p. 3

Do not ingest. Do not breathe dust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitablerespiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid contact withskin and eyes. Keep away from incompatibles such as alkalis.








Physical state and appearance: Solid. (Crystals solid. Granular powder solid. )

Odor: Odorless.



Color: White.

pH (1% soln/water): 4.5 [Acidic.] in a 5% soln/water












Solubility:Soluble in cold water. Insoluble in alcohol



p. 4


Conditions of Instability: Incompatible materials

Incompatibility with various substances: Reactive with alkalis.


Special Remarks on Reactivity:Loses water at 400 deg. C, forming metaphosphate. Incompatible with strong bases.




Routes of Entry: Absorbed through skin. Inhalation. Ingestion.

Toxicity to Animals: Acute dermal toxicity (LD50): >4640 mg/kg [Rabbit].


Other Toxic Effects on Humans:Hazardous in case of skin contact (irritant), of ingestion, of inhalation. Slightly hazardous in case of skin contact (permeator).

Special Remarks on Toxicity to Animals:Lowest Published Lethal Dose: LDL [Rat] - Route: Oral; Dose: 4640 mg/kg


Special Remarks on other Toxic Effects on Humans:Acute Potential Health Effects: Skin: May cause skin irritation. Risk of skin absorption is slight. Eyes: Dust may cause eyeirritation. Inhalation: Inhalation may cause respiratory tract irritation, coughing and choking. Ingestion: Ingestion of largeamounts may cause nausea, vomiting, abdominal discomfort (cramps), diarrhea. Also, symptoms of potassium poisoningmay occur, which may include slow heartbeat, peripheral vascular collapse with fall in blood pressure, cardiac arrythmias,heart block, accelerated breathing, and muscle weakness, heaviness of the legs, flaccid paralysis, cold skin, gray pallor, . Mayaffect behavior (listlessness, mental confusion), . Chronic Potential Health Effects: Dermatits may develop from repeated orprolonged skin contact.










p. 5





Federal and State Regulations: TSCA 8(b) inventory: Potassium phosphate monobasic




DSCL (EEC):This product is not classified according to the EU regulations. Not applicable.

HMIS (U.S.A.):

Health Hazard: 1

Fire Hazard: 0

Reactivity: 0



Health: 1

Flammability: 0

Reactivity: 0

Specific hazard:





Created: 10/10/2005 08:24 PM

Last Updated: 05/21/2013 12:00 PM


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Material Safety Data Sheetn-Propyl alcohol MSDS


Product Name: n-Propyl alcohol

Catalog Codes: SLP3403

CAS#: 71-23-8

RTECS: UH8225000

TSCA: TSCA 8(b) inventory: n-Propyl alcohol


Synonym: 1-Propanol

Chemical Name: Propanol

Chemical Formula: CH3CH2CH2OH







{n-}Propyl alcohol 71-23-8 100

Toxicological Data on Ingredients: n-Propyl alcohol: ORAL (LD50): Acute: 1870 mg/kg [Rat.]. 6800 mg/kg [Mouse].DERMAL (LD50): Acute: 4060 mg/kg [Rabbit.]. VAPOR (LC50): Acute: 67882.3 ppm 4 hour(s) [Mouse].


Potential Acute Health Effects:Very hazardous in case of eye contact (irritant). Hazardous in case of skin contact (irritant, permeator), of ingestion, ofinhalation. Inflammation of the eye is characterized by redness, watering, and itching.

Potential Chronic Health Effects:Slightly hazardous in case of skin contact (permeator). CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS:Not available. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available.


Eye Contact:Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelidsopen. Cold water may be used. Do not use an eye ointment. Seek medical attention.

p. 2

Skin Contact:After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with runningwater and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cold water may be used.Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated clothing beforereusing.




Ingestion:Do not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication thatthe toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen tight clothing such as a collar,tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention.




Auto-Ignition Temperature: 371°C (699.8°F)

Flash Points: CLOSED CUP: 15°C (59°F). OPEN CUP: 27.2°C (81°F) (Cleveland).

Flammable Limits: LOWER: 2.1% UPPER: 13.5%


Fire Hazards in Presence of Various Substances: Highly flammable in presence of open flames and sparks, of heat, ofoxidizing materials.



Special Remarks on Fire Hazards:Explosive in the form of vapor when exposed to heat or flame. Vapor may travel considerable distance to source of ignitionand flash back. When heated to decomposition it emits acrid smoke and irritating fumes. CAUTION: MAY BURN WITH NEARINVISIBLE FLAME




Large Spill:Flammable liquid. Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb with DRY earth,sand or other non-combustible material. Do not touch spilled material. Prevent entry into sewers, basements or confined

p. 3

areas; dike if needed. Eliminate all ignition sources. Be careful that the product is not present at a concentration level aboveTLV. Check TLV on the MSDS and with local authorities.


Precautions:Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Donot breathe gas/fumes/ vapour/spray. In case of insufficient ventilation, wear suitable respiratory equipment If ingested,seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes Keep away fromincompatibles such as oxidizing agents, acids.

Storage:Flammable materials should be stored in a separate safety storage cabinet or room. Keep away from heat. Keep away fromsources of ignition. Keep container tightly closed. Keep in a cool, well-ventilated place. Ground all equipment containingmaterial. A refrigerated room would be preferable for materials with a flash point lower than 37.8°C (100°F).





Exposure Limits:TWA: 200 STEL: 250 (ppm) from ACGIH (TLV) [1995] TWA: 492 STEL: 614 (mg/m3) from ACGIH [1995] Consult localauthorities for acceptable exposure limits.


Physical state and appearance: Liquid. (Liquid.)

Odor: Alcohol like.



Color: Colorless.


Boiling Point: 97.22°C (207°F)

Melting Point: -126.2°C (-195.2°F)



Vapor Pressure: 14.9 mm of Hg (@ 20°C)



p. 4

Odor Threshold: 5.3 ppm



Dispersion Properties: See solubility in water, methanol, diethyl ether.

Solubility: Easily soluble in cold water, hot water, methanol, diethyl ether.





Incompatibility with various substances: Reactive with oxidizing agents, acids.




Polymerization: No.


Routes of Entry: Dermal contact. Eye contact. Inhalation. Ingestion.

Toxicity to Animals:WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR EXPOSURE. Acute oraltoxicity (LD50): 1870 mg/kg [Rat.]. Acute dermal toxicity (LD50): 4060 mg/kg [Rabbit.]. Acute toxicity of the vapor (LC50):67882.3 ppm 4 hour(s) [Mouse].


Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant, permeator), of ingestion, of inhalation.



Special Remarks on other Toxic Effects on Humans: Exposure can cause nausea, headache and vomiting.








p. 5

Waste Disposal:


DOT Classification: Class 3: Flammable liquid.

Identification: : n-Propanol : UN1274 PG: III



Federal and State Regulations:Pennsylvania RTK: n-Propyl alcohol Massachusetts RTK: n-Propyl alcohol TSCA 8(b) inventory: n-Propyl alcohol



WHMIS (Canada):CLASS B-2: Flammable liquid with a flash point lower than 37.8°C (100°F). CLASS D-2B: Material causing other toxic effects(TOXIC).

DSCL (EEC):R11- Highly flammable. R38- Irritating to skin. R41- Risk of serious damage to eyes.

HMIS (U.S.A.):

Health Hazard: 1

Fire Hazard: 3

Reactivity: 0



Health: 1

Flammability: 3

Reactivity: 0

Specific hazard:



References:-Hawley, G.G.. The Condensed Chemical Dictionary, 11e ed., New York N.Y., Van Nostrand Reinold, 1987. -Material safetydata sheet emitted by: la Commission de la Santé et de la Sécurité du Travail du Québec. -SAX, N.I. Dangerous Propertiesof Indutrial Materials. Toronto, Van Nostrand Reinold, 6e ed. 1984. -The Sigma-Aldrich Library of Chemical Safety Data,Edition II. -Guide de la loi et du règlement sur le transport des marchandises dangeureuses au canada. Centre de conformitéinternatinal Ltée. 1986.


Created: 10/09/2005 06:13 PM

p. 6

Last Updated: 05/21/2013 12:00 PM


________________________________________________________________________________________________________________

SAFETY DATA SHEET



Eyes May cause eye irritation with susceptible persons.Skin May cause skin irritation in susceptible persons.Inhalation May be harmful by inhalation.Ingestion May be harmful if swallowed.

Signal Wordnot hazardous

Health Hazard


not hazardous


Product name S.O.C. MEDIUM

Physical Hazards

________________________________________________________________________________________________________________

not hazardous


15544034Revision Date

24 hour Emergency Response:


866-536-0631301-431-8585Outside of the U.S. +1-301-431-8585

Page 1 / 5

Product code

09-Jul-2013

15544034




Life Technologies5791 Van Allen WayPO Box 6482Carlsbad, CA 92008+1 760 603 7200

Product code

Life Technologies5250 Mainway DriveBurlingont, ONTCANADA L7L 6A4800/263-6236

Sensitization none

6. Ac c ident a l re lease m easures

Personal precautions Use personal protective equipment.Methods for cleaning up Soak up with inert absorbent material.

Mutagenic effects

4. Fi rs t a id m easures


Target Organ Effects

Prevent further leakage or spillage if safe to do so.


Skin contact Rinse with plenty of water. If symptoms arise, call a physician.

none


Specific effects

Eye contact Rinse immediately with plenty of water, also under the eyelids, for at least 15minutes. If symptoms persist, call a physician.

7. Handl ing and s t orage

Ingestion Never give anything by mouth to an unconscious person. If symptoms persist, calla physician. Do not induce vomiting without medical advice.

Inhalation Move to fresh air. If symptoms persist, call a physician. If not breathing, giveartificial respiration.

Notes to physician Treat symptomatically.

5. Fi re-f ight ing m easures

Reproductive toxicity none

HMIS

________________________________________________________________________________________________________________


Carcinogenic effects

Special protective equipment for firefighters Wear self-contained breathing apparatus and protectivesuit.

none

Health 0


15544034

Reactivity 0

Revision DateProduct name S.O.C. MEDIUM

Page 2 / 509-Jul-2013



Flammability

Product code

0

Prevent product from entering drains.

Oxidizing properties No information available.

9. Phys ic a l and c hem ic a l proper t ies



In case of insufficient ventilation wear suitable respiratory equipment.

Storage

General Information

10. St ab i l i t y and reac t iv i t y

Exposure limits


Engineering measures

Form

Materials to avoid No dangerous reaction known under conditions of normal use.

liquid

Hazardous decompositionproducts

None under normal use

Appearance



Ensure adequate ventilation, especially in confined areas.

Keep in a dry, cool and well-ventilated place.

Odor

11. Tox ic o log ic a l in form at ion


Hand protection Impervious gloves.

Acute toxicity

8. Ex posure c ont ro ls /personal prot ec t ion

Eye protection Safety glasses with side-shields.

Handling

Skin and body protection. Lightweight protective clothing.


________________________________________________________________________________________________________________

Hygiene measures Handle in accordance with good industrial hygiene and safety practice.

Always wear reccommended Personal Protective Equipment. No special handlingadvice required.

Personal Protective Equipment requirements are dependent on the user institution's risk assessment and are specificto the risk assessment for each laboratory where this material may be used.

15544034

We are not aware of any national exposure limit.


Revision Date



Melting point/range

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°C no data available

Autoignition temperature°C no data available

Boiling Point/Range

09-Jul-2013


Flash point


°C no data available°F no data available

Product code



13. Disposal c ons iderat ions


Sensitization

Dispose of in accordance with local regulations.

none

14. Transpor t in form at ion

Inhalation

Target Organ Effects No known effects under normal use conditions.

May be harmful by inhalation.

IATA


Proper shipping name Not classified as dangerous in the meaning of transport regulationsHazard class noneSubsidiary Class none

Ingestion May be harmful if swallowed.

Packing group none

12. Ec olog ic a l in form at ion

UN-No None

not hazardous

________________________________________________________________________________________________________________

Ecotoxicity effects No information available.

Eyes

Mobility No information available.

Carcinogenic effects none

Biodegradation Inherently biodegradable

15544034

May cause eye irritation with susceptible persons.

Revision Date

Bioaccumulation


Does not bioaccumulate.

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Mutagenic effects none

09-Jul-2013


Product code


The above information was acquired by diligent search and/or investigation and the recommendations are based onprudent application of professional judgment. The information shall not be taken as being all inclusive and is to beused only as a guide. All materials and mixtures may present unkown hazards and should be used with caution.Since the Company cannot control the actual methods, volumes, or conditions of use, the Company shall not be heldliable for any damages or losses resulting from the handling or from contact with the product as described herein.THE INFORMATION IN THIS MSDS DOES NOT CONSTITUTE A WARRENTY, EXPRESSED OR IMPLIED,INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PUPOSE.




WHMIS Hazard ClassNon-controlled

________________________________________________________________________________________________________________

This product has been classified according to the hazard criteria of the CPR and the MSDS contains all of the information requiredby the CPR

SARA 313This product is not regulated by SARA.





Product name S.O.C. MEDIUMPage 5 / 5

Clean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61)This product does not contains HAPs.

09-Jul-2013

California Proposition 65This product does not contain chemicals listed under Proposition 65


Product code

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Material Safety Data SheetSodium bicarbonate MSDS


Product Name: Sodium bicarbonate

Catalog Codes: SLS3241, SLS2446, SLS3868

CAS#: 144-55-8

RTECS: VZ0950000

TSCA: TSCA 8(b) inventory: Sodium bicarbonate

CI#: Not available.

Synonym: Baking Soda; Bicarbonate of soda; Sodiumacid carbonate; Monosodium carbonate; Sodium hydrogencarbonate; Carbonic acid monosodium salt

Chemical Name: Sodium Bicarbonate

Chemical Formula: NaHCO3







Sodium bicarbonate 144-55-8 100







p. 2
















Special Remarks on Fire Hazards: When heated to decomposition it emits acrid smoke and irritating fumes.






Precautions:Do not ingest. Do not breathe dust. If ingested, seek medical advice immediately and show the container or the label. Keepaway from incompatibles such as acids.



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Odor: Odorless.

Taste: Saline. Alkaline.

Molecular Weight: 84.01g/mole

Color: White.





Specific Gravity: Density: 2.159 (Water = 1)








Solubility:Soluble in cold water. Slightly soluble in alcohol. Solubility in Water: 6.4, 7.6, 8.7, 10.0, 11.3, 12.7, 14.2, 16.5, 19.1 g/100solution at 0, 10, 20, 30, 40, 50, 60, 80, adn 100 deg. C, respectively. Solubility in Water: 6.9, 8,2, 9.6, 11.1, 12.7, 14.5, 16.5,19.7, and 23.6 g/100g water at 0, 10, 20, 30, 40, 50, 60, 80, 100 deg. C, respectively.




Conditions of Instability: Incompatible materials, Moisture. Stable in dry air, but slowly decomposes in moist air.

Incompatibility with various substances: Reactive with acids.

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Special Remarks on Reactivity:Reacts with acids to form carbon dioxide. Dangerous reaction with monoammonium phosphate or a sodium-potassium alloy.





Toxicity to Animals: Acute oral toxicity (LD50): 3360 mg/kg [Mouse].




Special Remarks on Chronic Effects on Humans:Sodium Bicarbonate as produced genetic effects in rats (unscheduled DNA synthesis). However, no affects have been foundin humans.

Special Remarks on other Toxic Effects on Humans:Acute Potential Health Effects: Skin: May cause mild skin irritation. Eyes: May cause mild eye irritation. Inhalation: Maycause respiratory tract irritation. Symptoms may include coughing and sneezing. Ingestion: Symptoms of overexposure toSodium Bicarbonate include thirst, abdominal pain, gastroenteritis, and inflammation of the digestive tract. Chronic PotentialHealth Effects: Skin: Repeated or prolonged skin contact may cause irritation, drying or cracking of the skin. Ingestion andInhalation: Chronic toxicity usually occurs within 4 to 10 days following ingestion of very large amounts. Repeated or prolongedingestion or inhalation of large amounts may cause metabolic abnormalities, and sodium retention. Metabolic abnormalitiessuch as acidosis, hypernatremia, hypochloremia, alkalosis, hypocalcemia, or sodium retention may affect the blood, kidneys,respiration (cyanosis, apnea secondary to metabolic acidosis or pulmonary edema), and cardiovascular system (tachycardia,hypotension). Severe toxicity may also affect behavior/central nervous system/nervous system. Neurological changes mayresult from metabolic abnormalities. These may include fatigue, irritability, dizziness, mental confusion, paresthesia, seizures,tetany, cerebral edema Medical Conditions Aggravated by Exposure: Persons with pre-existing skin conditions might haveincreased sensitivity. Predisposing conditions that contribute to a mild alkali syndrome include, renal disease, dehydration, adnelectrolyte imbalance, hypertension, sarcoidosis, congestive heart failure, edema, or other sodium retaining conditions.










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Federal and State Regulations: TSCA 8(b) inventory: Sodium bicarbonate





HMIS (U.S.A.):

Health Hazard: 1

Fire Hazard: 0

Reactivity: 0



Health: 1

Flammability: 0

Reactivity: 0

Specific hazard:





Created: 10/10/2005 08:26 PM

Last Updated: 05/21/2013 12:00 PM


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Material Safety Data SheetSodium chloride MSDS


Product Name: Sodium chloride

Catalog Codes: SLS3262, SLS1045, SLS3889, SLS1669,SLS3091

CAS#: 7647-14-5

RTECS: VZ4725000

TSCA: TSCA 8(b) inventory: Sodium chloride


Synonym: Salt; Sea Salt

Chemical Name: Sodium chloride

Chemical Formula: NaCl







Sodium chloride 7647-14-5 100

Toxicological Data on Ingredients: Sodium chloride: ORAL (LD50): Acute: 3000 mg/kg [Rat.]. 4000 mg/kg [Mouse].DERMAL (LD50): Acute: >10000 mg/kg [Rabbit]. DUST (LC50): Acute: >42000 mg/m 1 hours [Rat].



Potential Chronic Health Effects:CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic forbacteria and/or yeast. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available. Repeated orprolonged exposure is not known to aggravate medical condition.


Eye Contact:

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Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Cold water may be used. Get medical attention.Skin Contact:Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold watermay be used.Serious Skin Contact: Not available.Inhalation:If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medicalattention if symptoms appear.Serious Inhalation: Not available.Ingestion:Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconsciousperson. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.Serious Ingestion: Not available.


Flammability of the Product: Non-flammable.Auto-Ignition Temperature: Not applicable.Flash Points: Not applicable.Flammable Limits: Not applicable.Products of Combustion: Not available.Fire Hazards in Presence of Various Substances: Not applicable.Explosion Hazards in Presence of Various Substances:Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product inpresence of static discharge: Not available.Fire Fighting Media and Instructions: Not applicable.Special Remarks on Fire Hazards: When heated to decomposition it emits toxic fumes.Special Remarks on Explosion Hazards:Electrolysis of sodium chloride in presence of nitrogenous compounds to produce chlorine may lead to formation of explosivenitrogen trichloride. Potentially explosive reaction with dichloromaleic anhydride + urea.


Small Spill:Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water onthe contaminated surface and dispose of according to local and regional authority requirements.Large Spill:Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on thecontaminated surface and allow to evacuate through the sanitary system.


Precautions:Keep locked up.. Do not ingest. Do not breathe dust. Avoid contact with eyes. Wear suitable protective clothing. If ingested,seek medical advice immediately and show the container or the label. Keep away from incompatibles such as oxidizingagents, acids.

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Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area. Hygroscopic







Physical state and appearance: Solid. (Solid crystalline powder.)

Odor: Slight.

Taste: Saline.


Color: White.













Solubility:Easily soluble in cold water, hot water. Soluble in glycerol, and ammonia. Very slightly soluble in alcohol. Insoluble inHydrochloric Acid.



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Conditions of Instability: Incompatible materials, high temperatures.

Incompatibility with various substances: Reactive with oxidizing agents, metals, acids.

Corrosivity: Not considered to be corrosive for metals and glass.

Special Remarks on Reactivity:Hygroscopic. Reacts with most nonnoble metals such as iron or steel, building materials (such as cement) Sodium chloride israpidly attacked by bromine trifluoride. Violent reaction with lithium.





Toxicity to Animals:WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR EXPOSURE. Acute oraltoxicity (LD50): 3000 mg/kg [Rat.]. Acute dermal toxicity (LD50): >10000 mg/kg [Rabbit]. Acute toxicity of the dust (LC50):>42000 mg/m3 1 hours [Rat].

Chronic Effects on Humans: MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast.


Special Remarks on Toxicity to Animals: Lowest Published Lethal Dose (LDL) [Man] - Route: Oral; Dose: 1000 mg/kg

Special Remarks on Chronic Effects on Humans:Causes adverse reproductive effects in humans (fetotoxicity, abortion, ) by intraplacental route. High intake of sodium chloride,whether from occupational exposure or in the diet, may increase risk of TOXEMIA OF PREGNANCY in susceptible women(Bishop, 1978). Hypertonic sodium chloride solutions have been used to induce abortion in late pregnancy by direct infusioninto the uterus (Brown et al, 1972), but this route of administration is not relevant to occupational exposures. May causeadverse reproductive effects and birth defects in animals, particularly rats and mice (fetotoxicity, abortion, musculoskeletalabnormalities, and maternal effects (effects on ovaries, fallopian tubes) by oral, intraperitoneal, intraplacental, intrauterine,parenteral, and subcutaneous routes. While sodium chloride has been used as a negative control n some reproductivestudies, it has also been used as an example that almost any chemical can cause birth defects in experimental animalsif studied under the right conditions (Nishimura & Miyamoto, 1969). In experimental animals, sodium chloride has causeddelayed effects on newborns, has been fetotoxic, and has caused birth defects and abortions in rats and mice (RTECS, 1997).May affect genetic material (mutagenic)

Special Remarks on other Toxic Effects on Humans:Acute Potential Health Effects: Skin: May cause skin irritation. Eyes: Causes eye irritation. Ingestion: Ingestion of largequantities can irritate the stomach (as in overuse of salt tablets) with nausea and vomiting. May affect behavior (musclespasicity/contraction, somnolence), sense organs, metabolism, and cardiovascular system. Continued exposure mayproduce dehydration, internal organ congestion, and coma. Inhalation: Material is irritating to mucous membranes and upperrespiratory tract.






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Federal and State Regulations: TSCA 8(b) inventory: Sodium chloride




DSCL (EEC):R40- Possible risks of irreversible effects. S24/25- Avoid contact with skin and eyes.

HMIS (U.S.A.):

Health Hazard: 1

Fire Hazard: 0

Reactivity: 0



Health: 1

Flammability: 0

Reactivity: 0

Specific hazard:





Created: 10/11/2005 12:33 PM

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Last Updated: 05/21/2013 12:00 PM


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Material Safety Data SheetSodium hydroxide MSDS


Product Name: Sodium hydroxide

Catalog Codes: SLS3298, SLS1081, SLS2503, SLS3925,SLS1705

CAS#: 1310-73-2

RTECS: WB4900000

TSCA: TSCA 8(b) inventory: Sodium hydroxide

CI#: Not available.

Synonym: Caustic Soda

Chemical Name: Sodium Hydroxide

Chemical Formula: NaOH







Sodium hydroxide 1310-73-2 100

Toxicological Data on Ingredients: Sodium hydroxide LD50: Not available. LC50: Not available.


Potential Acute Health Effects:Very hazardous in case of skin contact (corrosive, irritant, permeator), of eye contact (irritant, corrosive), of ingestion,of inhalation. The amount of tissue damage depends on length of contact. Eye contact can result in corneal damage orblindness. Skin contact can produce inflammation and blistering. Inhalation of dust will produce irritation to gastro-intestinal orrespiratory tract, characterized by burning, sneezing and coughing. Severe over-exposure can produce lung damage, choking,unconsciousness or death. Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation ischaracterized by itching, scaling, reddening, or, occasionally, blistering.Potential Chronic Health Effects:CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells.TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available. The substance may be toxic tomucous membranes, upper respiratory tract, skin, eyes. Repeated or prolonged exposure to the substance can produce targetorgans damage. Repeated exposure of the eyes to a low level of dust can produce eye irritation. Repeated skin exposure canproduce local skin destruction, or dermatitis. Repeated inhalation of dust can produce varying degree of respiratory irritation orlung damage.

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Eye Contact:Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15minutes. Cold water may be used. Get medical attention immediately.

Skin Contact:In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothingand shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before reuse. Thoroughly cleanshoes before reuse. Get medical attention immediately.












Fire Hazards in Presence of Various Substances: metals

Explosion Hazards in Presence of Various Substances:Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product inpresence of static discharge: Not available. Slightly explosive in presence of heat.

Fire Fighting Media and Instructions: Not available

Special Remarks on Fire Hazards:sodium hydroxide + zinc metal dust causes ignition of the latter. Under proper conditions of temperature, pressure and stateof division, it can ignite or react violently with acetaldehyde, ally alcohol, allyl chloride, benzene-1,4-diol, chlorine trifluoride,1,2 dichlorethylene, nitroethane, nitromethane, nitroparaffins, nitropropane, cinnamaldehyde, 2,2-dichloro-3,3-dimethylbutane.Sodium hydroxide in contact with water may generate enough heat to ignite adjacent combustible materials. Phosphorousboiled with NaOH yields mixed phosphines which may ignite spontanously in air. sodium hydroxide and cinnamaldehyde +heat may cause ignition. Reaction with certain metals releases flammable and explosive hydrogen gas.

Special Remarks on Explosion Hazards:Sodium hydroxide reacts to form explosive products with ammonia + silver nitrate. Benzene extract of allyl benzenesulfonateprepared from allyl alcohol, and benzene sulfonyl chloride in presence of aquesous sodium hydroxide, under vacuumdistillation, residue darkened and exploded. Sodium Hydroxde + impure tetrahydrofuran, which can contain peroxides, can

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cause serious explosions. Dry mixtures of sodium hydroxide and sodium tetrahydroborate liberate hydrogen explosively at230-270 deg. C. Sodium Hydroxide reacts with sodium salt of trichlorophenol + methyl alcohol + trichlorobenzene + heat tocause an explosion.


Small Spill:Use appropriate tools to put the spilled solid in a convenient waste disposal container. If necessary: Neutralize the residue witha dilute solution of acetic acid.

Large Spill:Corrosive solid. Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water sprayto reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Call for assistance on disposal.Neutralize the residue with a dilute solution of acetic acid. Be careful that the product is not present at a concentration levelabove TLV. Check TLV on the MSDS and with local authorities.


Precautions:Keep container dry. Do not breathe dust. Never add water to this product. In case of insufficient ventilation, wear suitablerespiratory equipment. If you feel unwell, seek medical attention and show the label when possible. Avoid contact with skinand eyes. Keep away from incompatibles such as oxidizing agents, reducing agents, metals, acids, alkalis, moisture.

Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area. Hygroscopic. Deliquescent.



Personal Protection:Splash goggles. Synthetic apron. Vapor and dust respirator. Be sure to use an approved/certified respirator or equivalent.Gloves.

Personal Protection in Case of a Large Spill:Splash goggles. Full suit. Vapor and dust respirator. Boots. Gloves. A self contained breathing apparatus should be used toavoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handlingthis product.

Exposure Limits:STEL: 2 (mg/m3) from ACGIH (TLV) [United States] TWA: 2 CEIL: 2 (mg/m3) from OSHA (PEL) [United States] CEIL: 2 (mg/m3) from NIOSHConsult local authorities for acceptable exposure limits.


Physical state and appearance: Solid. (Deliquescent solid.)

Odor: Odorless.


Molecular Weight: 40 g/mole

Color: White.

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pH (1% soln/water): 13.5 [Basic.]
















Conditions of Instability: Incompatible materials, moisture, moist air

Incompatibility with various substances:Highly reactive with metals. Reactive with oxidizing agents, reducing agents, acids, alkalis, moisture.


Special Remarks on Reactivity:Hygroscopic. Much heat is evolved when solid material is dissolved in water. Therefore cold water and caution must be usedfor this process. Sodium hydroxide solution and octanol + diborane during a work-up of a reaction mixture of oxime anddiborane in tetrahyrofuran is very exothermic, a mild explosion being noted on one occassion. Reactive with water, acids(mineral, non-oxidizing, e.g. hydrochloric, hydrofluoric acid, muriatic acid, phosphoric), acids (mineral, oxidizing e.g. chromicacid, hypochlorous acid, nitric acid, sulfuric acid), acids (organic e.g. acetic acid, benzoic acid, formic acid, methanoic acid,oxalic acid), aldehydes (e.g. acetaldehyde, acrolein, chloral hydrate, foraldehyde), carbamates (e.g. carbanolate, carbofuran),esters (e.g. butyl acetate, ethyl acetate, propyl formate), halogenated organics (dibromoethane, hexachlorobenzene, methylchloride, trichloroethylene), isocyanates (e.g. methyl isocyanate), ketones (acetone, acetophenone, MEK, MIBK), acidchlorides, strong bases, strong oxidizing agents, strong reducing agents, flammable liquids, powdered metals and metals (i.ealuminum, tin, zinc, hafnium, raney nickel), metals (alkali and alkaline e.g. cesium, potassium, sodium), metal compounds(toxic e.g. berylium, lead acetate, nickel carbonyl, tetraethyl lead), mitrides (e.g. potassium nitride, sodium nitride), nitriles(e.g. acetonitrile, methyl cyanide), nitro compounds (organic e.g. nitrobenzene, nitromethane), acetic anhydride, chlorohydrin,chlorosulfonic acid, ethylene cyanohydrin, glyoxal, hydrosulfuric acid, oleum, propiolactone, acylonitrile, phorosous pentoxide,chloroethanol, chloroform-methanol, tetrahydroborate, cyanogen azide, 1,2,4,5 tetrachlorobenzene, cinnamaldehyde. Reactswith formaldehyde hydroxide to yield formic acid, and hydrogen.

Special Remarks on Corrosivity: Very caustic to aluminum and other metals in presence of moisture.



Routes of Entry: Absorbed through skin. Dermal contact. Eye contact. Inhalation. Ingestion.

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Chronic Effects on Humans:MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. May cause damage to the following organs: mucousmembranes, upper respiratory tract, skin, eyes.

Other Toxic Effects on Humans:Extremely hazardous in case of inhalation (lung corrosive). Very hazardous in case of skin contact (corrosive, irritant,permeator), of eye contact (corrosive), of ingestion, .

Special Remarks on Toxicity to Animals:Lowest Published Lethal Dose: LDL [Rabbit] - Route: Oral; Dose: 500 mg/kg

Special Remarks on Chronic Effects on Humans: May affect genetic material. Investigation as a mutagen (cytogeneticanalysis)

Special Remarks on other Toxic Effects on Humans:










DOT Classification: Class 8: Corrosive material

Identification: : Sodium hydroxide, solid UNNA: 1823 PG: II



Federal and State Regulations:Illinois toxic substances disclosure to employee act: Sodium hydroxide Illinois chemical safety act: Sodium hydroxide NewYork release reporting list: Sodium hydroxide Rhode Island RTK hazardous substances: Sodium hydroxide PennsylvaniaRTK: Sodium hydroxide Minnesota: Sodium hydroxide Massachusetts RTK: Sodium hydroxide New Jersey: Sodium hydroxideLouisiana spill reporting: Sodium hydroxide California Director's List of Hazardous Substances: Sodium hydroxide TSCA 8(b)inventory: Sodium hydroxide CERCLA: Hazardous substances.: Sodium hydroxide: 1000 lbs. (453.6 kg)


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WHMIS (Canada): CLASS E: Corrosive solid.

DSCL (EEC):R35- Causes severe burns. S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.S37/39- Wear suitable gloves and eye/face protection. S45- In case of accident or if you feel unwell, seek medical adviceimmediately (show the label where possible).

HMIS (U.S.A.):

Health Hazard: 3

Fire Hazard: 0

Reactivity: 2

Personal Protection: j


Health: 3

Flammability: 0

Reactivity: 1

Specific hazard:

Protective Equipment:Gloves. Synthetic apron. Vapor and dust respirator. Be sure to use an approved/certified respirator or equivalent. Wearappropriate respirator when ventilation is inadequate. Splash goggles.




Created: 10/09/2005 06:32 PM

Last Updated: 05/21/2013 12:00 PM


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Material Safety Data SheetSodium phosphate monobasic, Anhydrous MSDS


Product Name: Sodium phosphate monobasic, Anhydrous

Catalog Codes: SLS3160, SLS4582

CAS#: 7558-80-7

RTECS: WA1900000

TSCA: TSCA 8(b) inventory: Sodium phosphatemonobasic, Anhydrous

CI#: Not available.

Synonym: Sodium phosphate monobasic; sodiumdihydrogen phosphate; Monosodium DihydrogenPhosphate; Monosodium Hydrogen Phosphate;Monsodium Orthophosphate, Phosphoric Acid,Monosodium Salt

Chemical Name: Sodium Phosphate Monobasic,Anhydrous

Chemical Formula: NaH2PO4







Sodium phosphate monobasic, Anhydrous 7558-80-7 100






p. 2













Products of Combustion: When heated to decomp ... emits toxic fumes of phosphoxides and sodium oxide.










Precautions:Do not ingest. Do not breathe dust. If ingested, seek medical advice immediately and show the container or the label. Keepaway from incompatibles such as acids, alkalis.

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Physical state and appearance: Solid. (crystalline powder)

Odor: Odorless.



Color: White.













Solubility: Easily soluble in cold water, hot water.




Conditions of Instability: Incompatible materials, excess heat, dust generation

p. 4

Incompatibility with various substances: Reactive with acids, alkalis.


Special Remarks on Reactivity:It is a neutralizing agent for acids and caustics. Also incompatible with magnesium and methenamine, and carbonates.

Special Remarks on Corrosivity: When wet, mild steel or brass may be corroded.









Special Remarks on other Toxic Effects on Humans:Acute Potential Health Effects: Skin: May cause skin irritation. Eye: Dust may cause eye irritation. Inhalation: It is considereda low hazard for ususal industrial handling. Dust may cause respiratory tract irritation and may affect respiration (mechanicallyimpede respiration). Ingestion: It is considered a low hazard for usual industrial handling and systemic reactions are unlikelywhen ingested (because they are slowly and incompletely absorbed in the intestinal tract). The most frequently seen effectis gastrointestinal irritation with abdominal pain and cramping, vomiting, diarrhea. If a significant amount of phosphate isasborbed, the following may occur: mineral imbalance in the body, adversely affecting the osmotic pressure of body fluidsresulting in hyperphosphatemia, hypocalcemia, hypomagnesemia. Severe hyperphosphatemia and hypocalcemia may resultin tetany, seizures, severe dehydration, metabolic acidosis, hypernaturemia, lethargy, and hyperpyrexia, carpal spasm, andpossible. May also affect the cardiovascular system (hypotension, tachycardia, bradycardia, dysrhythmias). The estimatedfatal dose is 50 grams. Chronic Potential Health Effects: No information was available.











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Federal and State Regulations: TSCA 8(b) inventory: Sodium phosphate monobasic, Anhydrous





HMIS (U.S.A.):

Health Hazard: 1

Fire Hazard: 0

Reactivity: 0



Health: 1

Flammability: 0

Reactivity: 0

Specific hazard:





Created: 10/09/2005 06:34 PM

Last Updated: 05/21/2013 12:00 PM


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Material Safety Data SheetSodium phosphate monobasic monohydrate MSDS


Product Name: Sodium phosphate monobasicmonohydrate

Catalog Codes: SLS1165, SLS4009

CAS#: 10049-21-5

RTECS: WA1900000


CI#: Not available.

Synonym: Dihydrogen Sodium Phosphate; Sodiumdihydrogen phosphate monhydrate; Sodium Biphosphatemonohydrate; sodium dihydrogen orthophosphatemonobasic; Sodium Phosphate, Monobasic, Hydrate

Chemical Name: Sodium Phosphate, Monobasic,Monohydrate

Chemical Formula: NaH2PO4.H2O







Sodium phosphate monobasic monohydrate 10049-21-5 100

Toxicological Data on Ingredients: Sodium phosphate monobasic monohydrate LD50: Not available. LC50: Not available.



Potential Chronic Health Effects: CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available.TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available. Repeated exposure to a highly toxicmaterial may produce general deterioration of health by an accumulation in one or many human organs.


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Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for atleast 15 minutes. Cold water may be used. Get medical attention if irritation occurs.Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.Cold water may be used.Serious Skin Contact: Not available.Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Getmedical attention.Serious Inhalation: Not available.Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to anunconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing suchas a collar, tie, belt or waistband.Serious Ingestion: Not available.


Flammability of the Product: Non-flammable.Auto-Ignition Temperature: Not applicable.Flash Points: Not applicable.Flammable Limits: Not applicable.Products of Combustion: Hazardous decomposition products include Carbon monoxide, oxides of phosphorous, CarbondioxideFire Hazards in Presence of Various Substances: Not applicable.Explosion Hazards in Presence of Various Substances: Risks of explosion of the product in presence of mechanicalimpact: Not available. Risks of explosion of the product in presence of static discharge: Not available.Fire Fighting Media and Instructions: Not applicable.Special Remarks on Fire Hazards: Not available.Special Remarks on Explosion Hazards: Not available.


Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning byspreading water on the contaminated surface and dispose of according to local and regional authority requirements.Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading wateron the contaminated surface and allow to evacuate through the sanitary system.


Precautions: Do not breathe dust. Keep away from incompatibles such as acids, alkalis.Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area. Hygroscopic


Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airbornelevels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure toairborne contaminants below the exposure limit.

p. 3


Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self containedbreathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient;consult a specialist BEFORE handling this product.




Odor: Odorless.



Color: White.

















Conditions of Instability: Incompatible materials, dust generation, excess heat, moisture.

Incompatibility with various substances: Reactive with acids, alkalis.


Special Remarks on Reactivity: Hygroscopic. It is a neutralizing agent for acids and caustics. Also incompatible withmagnesium and methenamine, and carbonates.

Special Remarks on Corrosivity: May corrode some metals in the presence of moisture. May be mildly corrosive toaluminum or steel.


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Special Remarks on other Toxic Effects on Humans: Acute Potential Health Effects: Skin: May cause skin irritation.Eye: Dust may cause eye irritation. Inhalation: It is considered a low hazard for ususal industrial handling. Dust may causerespiratory tract irritation and may affect respiration (mechanically impede respiration). Ingestion: It is considered a low hazardfor usual industrial handling and systemic reactions are unlikely when ingested (because they are slowly and incompletelyabsorbed in the intestinal tract). The most frequently seen effect is gastrointestinal irritation with abdominal pain and cramping,vomiting, diarrhea. If a significant amount of phosphate is asborbed, the following may occur: mineral imbalance in the body,adversely affecting the osmotic pressure of body fluids resulting in hyperphosphatemia, hypocalcemia, hypomagnesemia.Severe hyperphosphatemia and hypocalcemia may result in tetany, seizures, severe dehydration, metabolic acidosis,hypernaturemia, lethargy, and hyperpyrexia, carpal spasm, and possible. May also affect the cardiovascular system(hypotension, tachycardia, bradycardia, dysrhythmias). The estimated fatal dose is 50 grams. Chronic Potential Health Effects:No information was available.








Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations.






Federal and State Regulations: No products were found.



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DSCL (EEC): This product is not classified according to the EU regulations. Not applicable.

HMIS (U.S.A.):

Health Hazard: 1

Fire Hazard: 0

Reactivity: 0



Health: 1

Flammability: 0

Reactivity: 0

Specific hazard:

Protective Equipment: Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.Splash goggles.




Created: 10/09/2005 06:34 PM

Last Updated: 05/21/2013 12:00 PM


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Material Safety Data SheetAmmonium persulfate MSDS


Product Name: Ammonium persulfate

Catalog Codes: SLA4228, SLA3385

CAS#: 7727-54-0

RTECS: SE0350000

TSCA: TSCA 8(b) inventory: Ammonium persulfate

CI#: Not available.

Synonym: Ammonium peroxydisulfate

Chemical Name: Ammonium Persulfate

Chemical Formula: (NH4)2S2O8







Ammonium persulfate 7727-54-0 100

Toxicological Data on Ingredients: Ammonium persulfate: ORAL (LD50): Acute: 689 mg/kg [Rat].


Potential Acute Health Effects:Hazardous in case of skin contact (irritant, sensitizer), of eye contact (irritant), of ingestion, of inhalation (lung irritant, lungsensitizer). Prolonged exposure may result in skin burns and ulcerations. Over-exposure by inhalation may cause respiratoryirritation.

Potential Chronic Health Effects:CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available. The substance may be toxic to upper respiratory tract. Repeated or prolongedexposure to the substance can produce target organs damage.


Eye Contact:

p. 2


Skin Contact:In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothingand shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before reuse. Thoroughly cleanshoes before reuse. Get medical attention.



Serious Inhalation:Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. Ifbreathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. WARNING: It maybe hazardous to the person providing aid to give mouth-to-mouth resuscitation when the inhaled material is toxic, infectious orcorrosive. Seek medical attention.






Flash Points: CLOSED CUP: Higher than 93.3°C (200°F).



Fire Hazards in Presence of Various Substances:Slightly flammable to flammable in presence of open flames and sparks, of heat, of reducing materials, of combustiblematerials.

Explosion Hazards in Presence of Various Substances:Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product inpresence of static discharge: Not available. Slightly explosive in presence of reducing materials, of combustible materials, oforganic materials, of metals.

Fire Fighting Media and Instructions:Oxidizing material. Do not use water jet. Use flooding quantities of water. Avoid contact with organic materials.




Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container.

Large Spill:

p. 3

Oxidizing material. Stop leak if without risk. Avoid contact with a combustible material (wood, paper, oil, clothing...). Keepsubstance damp using water spray. Do not touch spilled material. Prevent entry into sewers, basements or confined areas;dike if needed. Eliminate all ignition sources. Call for assistance on disposal.


Precautions:Keep away from heat. Keep away from sources of ignition. Keep away from combustible material.. Empty containers pose afire risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathedust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested,seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes. Keep away fromincompatibles such as reducing agents, combustible materials, organic materials, metals.

Storage:Strong Oxidizer. Moisture Sensitive. Keep container tightly closed. Keep container in a cool, well-ventilated area. Separatefrom acids, alkalies, reducing agents and combustibles. See NFPA 43A, Code for the Storage of Liquid and Solid Oxidizers.Do not store above 23°C (73.4°F).








Odor: Unpleasant. (Slight.)



Color: White to yellowish. (Light.)



Melting Point: 120°C (248°F)





p. 4






Solubility: Soluble in cold water, hot water.




Conditions of Instability: Excess heat, ignition sources, incompatible materials

Incompatibility with various substances: Reactive with reducing agents, combustible materials, organic materials, metals.


Special Remarks on Reactivity:Strong oxider. Moisture sensitive. May decompose on exposure to moist air or water. May be shock sensitive and thermallyunstable. Decomposes when heated. Incompatible with powdered aluminum, iron, sodium peroxide.






Chronic Effects on Humans: May cause damage to the following organs: upper respiratory tract.

Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant, sensitizer), of ingestion, of inhalation (lungirritant, lung sensitizer).



Special Remarks on other Toxic Effects on Humans:Acute Potential Health Effects: Skin: Causes skin irritation. May cause skin sensitization, an allergic reation, which becomesevident upon re-exposure to this material. Eyes: Causes eye irritation. Ingestion: Causes gastrointestinal (digestive) tractirritation with nausea, vomiting, and diarrhea. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. Maycause chemical pneumonitis and pulmonary edema, inflammation, edema of bronchi and larynx. Chronic Potential HealthEffects: Repeated or prolonged skin exposure may cause allergic reactions in sensitive individuals. Repeated or prolongedexposure by inhalation may affect respiration and metabolism.




Products of Biodegradation:

p. 5

Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.






DOT Classification: CLASS 5.1: Oxidizing material.

Identification: : Ammonium Persulfate UNNA: 1444 PG: III



Federal and State Regulations:Connecticut hazardous material survey.: Ammonium persulfate New Jersey: Ammonium persulfate TSCA 8(b) inventory:Ammonium persulfate



WHMIS (Canada): CLASS C: Oxidizing material.

DSCL (EEC):R8- Contact with combustible material may cause fire. R20/22- Harmful by inhalation and if swallowed. R36/37/38- Irritatingto eyes, respiratory system and skin. R42/43- May cause sensitization by inhalation and skin contact. S22- Do not breathedust. S24- Avoid contact with skin. S26- In case of contact with eyes, rinse immediately with plenty of water and seek medicaladvice. S37- Wear suitable gloves.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 1

Reactivity: 3



Health: 2

Flammability: 1

Reactivity: 3

Specific hazard:

Protective Equipment:Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respiratorwhen ventilation is inadequate. Splash goggles.

p. 6




Created: 10/09/2005 03:58 PM

Last Updated: 05/21/2013 12:00 PM


________________________________________________________________________________________________________________

Safety Data Sheet

Product code

Country specific Emergency Number (if available):

Company/undertaking identification

HC2006

Identification of the substance or mixture

Health hazards Acute oral toxicity Category 4

Product name

Acute Inhalation Toxicity - Vapors Category 4

TEMED


________________________________________________________________________________________________________________

SECTION 2: Hazards ident i f ic at ion

SECTION 1: Ident i f ic at ion of t he subst anc e/m ix t ure and of t he c om pany/under t ak ing

HC2006


Revision date


Product name TEMED

866-536-0631301-431-8585Outside of the U.S. +1-301-431-8585

Page 1 / 610-Sep-2015

Signal WordDANGER

CHEMTREC Brazil (Rio De Janeiro)

www.thermofisher.com

+(55)-2139581449 (português)

Product code

Life Technologies5250 Mainway DriveBurlington, ONTCANADA L7L 6A4800/263-6236


Ingestion Harmful if swallowed.

Skin corrosion/irritation

Precautionary StatementsP301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomitingP303 + P361 + P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin withwater/showerP304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathingP305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, ifpresent and easy to do. Continue rinsingP307 + P311 - IF exposed: Call a POISON CENTER or doctor/physicianP210 - Keep away from heat/sparks/open flames/hot surfaces. - No smokingP280 - Wear protective gloves/protective clothing/eye protection/face protection

Specific effects Carcinogenic effects None.Mutagenic effects None.Reproductive toxicity None.

Hazard StatementsH225 - Highly flammable liquid and vaporH302 + H332 - Harmful if swallowed or if inhaledH314 - Causes severe skin burns and eye damage

Sensitization None.

Principle Routes of Exposure Potential Health Effects

Category 1 B

Target Organ Effects None.

eyes Risk of serious damage to eyes.Skin

HMIS

Causes burns.inhalation Harmful by inhalation.

Physical hazards

SECTION 3: Com posi t ion/in form at ion on ingredient s

________________________________________________________________________________________________________________

Reactivity 0

GHS Physical Hazard 1

Chemical Name CAS-No EINECS-No Weight %

GHS Physical Hazard Category Number Category 2

HC2006

1,2-Bis(dimethylamino)ethane 110-18-9

Revision date

203-744-6

Product name TEMED

60-100

Page 2 / 6

Flammable liquids

We recommend handling all chemicals with caution.

Flammability

10-Sep-2015

3


Health 3

Product code

SECTION 6: Ac c ident a l re lease m easures

inhalation

SECTION 8: Ex posure c ont ro ls /personal prot ec t ion

Remove to fresh air. If not breathing, give artificial respiration. Call a physician orpoison control center immediately.

SECTION 4: Fi rs t a id m easures

Personal precautions

Exposure Limits

Ensure adequate ventilation. Avoid contact with skin, eyes or clothing. Usepersonal protection equipment.

SECTION 5: Fi re f ight ing m easures

Eye contact

Methods for cleaning up

Chemical Name OSHA PEL OSHA PEL (Ceiling) ACGIH OEL (TWA) ACGIH OEL (STEL)

Soak up with inert absorbent material.

Most important symptoms and effects, both acute and delayed

1,2-Bis(dimethylamino)ethane

None None None None

Rinse immediately with plenty of water, also under the eyelids, for at least 15minutes. Immediate medical attention is required.

Engineering measures Ensure adequate ventilation, especially in confined areas.


Suitable extinguishing media

Personal Protective Equipment

Water spray. Carbon dioxide (CO2). Foam. Dry chemical.


H225 - Highly flammable liquid and vapor, H302 + H332 - Harmful if swallowed or if inhaled, H314 - Causes severeskin burns and eye damage

Skin contact

Prevent further leakage or spillage if safe to do so. Prevent product from entering drains.

________________________________________________________________________________________________________________


Ingestion

See Section 12 for more information.

Specific hazards arising from the chemical Not known

HC2006

Call a physician or poison control center immediately. Never give anything bymouth to an unconscious person. Do not induce vomiting without medical advice.

SECTION 7: Handl ing and s t orage

Revision dateProduct name TEMED

Page 3 / 6

Wash off immediately with plenty of water for at least 15 minutes. Take off allcontaminated clothing and wash it before reuse. Immediate medical attention isrequired.

Notes to Physician

Handling

10-Sep-2015

Always wear reccommended Personal Protective Equipment. No special handlingadvices are necessary.


Treat symptomatically.

Storage

Product code

Keep in a dry, cool and well-ventilated place. Keep in properly labeled containers.

Partition coefficient:n-octanol/water

No data available

Vapor Pressure No data availablevapor density No data availableViscosity Mixture has not been tested

Eye protection

SECTION 9: Phys ic a l and c hem ic a l proper t ies

Wear safety glasses with side shields (or goggles).

SECTION 10: St ab i l i t y and reac t iv i t y


General information

Materials to avoid No information available.

Skin and Body Protection Lightweight protective clothing.

Possibility of hazardousreactions

Hazardous reaction has not been reported


Form


No information available.

Liquid

Hygiene measures

polymerization None under normal processing.

Appearance No information available

Conditions to avoid None under normal processing.

Handle in accordance with good industrial hygiene and safety practice.

Evaporation rate No data available

Odor Mixture has not been tested

Flammability (solid, gas) No data available

In case of insufficient ventilation, wear suitable respiratory equipment.

Oxidizing properties Mixture has not been tested

Odor Threshold Mixture has not been tested

Water solubility No data available

________________________________________________________________________________________________________________

Upper explosion limit No data available


Prevent product from entering drains. Do not allow material to contaminate groundwater system.

Lower explosion limit No data available

Hand protection

HC2006

Impervious gloves.

Revision date

Melting point / melting range

Product name TEMED

°C No data available

Page 4 / 6

Autoignition Temperature°C <23

Boiling point / boiling range °F >95

10-Sep-2015

flash point°C No data available


°F <73.5

°C >35

Product code

°F No data available

°F No data available

No data available No data available =1318ppm(Rat)

Acute Toxicity


SECTION 13: Disposal c ons iderat ions

None.

Dispose of contents/containers in accordance with local regulations.

Mutagenic effects None.

SECTION 14: Transpor t in form at ion

Reproductive toxicity None.

Principle Routes of Exposure Potential Health Effects

IATA

Sensitization None.

Proper Shipping Name 1,2-Di-(dimethylamino) ethane

SECTION 11: Tox ic o log ic a l in form at ion

Hazard Class 3

Chemical Name

Subsidiary class NonePacking group II

Target Organ Effects None

UN-No 2372

eyes Risk of serious damage to eyes.

Environmental hazards None

LD50 (oral,rat/mouse) LD50 (dermal,rat/rabbit)

________________________________________________________________________________________________________________

Skin

SECTION 12: Ec olog ic a l in form at ion

Causes burns.

LC50 (inhalation,rat/mouse)

Ecotoxicity

HC2006

Contains no substances known to be hazardous to the environment or notdegradable in waste water treatment plants.

inhalation

Revision date

Harmful by inhalation.

Product name TEMED

Mobility

Page 5 / 6


1,2-Bis(dimethylamino)ethane

Biodegradation

10-Sep-2015



Ingestion

Bioaccumulation

Product code


Harmful if swallowed.

Reason for revision SDS sections updated.

"The above information was acquired by diligent search and/or investigation and the recommendations are based onprudent application of professional judgment. The information shall not be taken as being all inclusive and is to beused only as a guide. All materials and mixtures may present unknown hazards and should be used with caution.Since the Company cannot control the actual methods, volumes, or conditions of use, the Company shall not be heldliable for any damages or losses resulting from the handling or from contact with the product as described herein.THE INFORMATION IN THIS SDS DOES NOT CONSTITUTE A WARRENTY, EXPRESSED OR IMPLIED,INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PUPOSE"

SECTION 16: Ot her in form at ion



WHMIS Hazard ClassB2 - Flammable liquidE - Corrosive material

SECTION 15: Regulat ory in form at ion

1,2-Bis(dimethylamino)ethane 110-18-9 ( 60-100 )

This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and theMSDS contains all the information required by the CPR.

US State Regulations

Listed


________________________________________________________________________________________________________________

Component

Chemical Name Massachusetts - RTK New Jersey - RTK Pennsylvania - RTK Illinois - RTK Rhode Island - RTK1,2-Bis(dimethylamino)ethane

HC2006

- Listed

Revision date

-

Product name TEMED

-

Page 6 / 6

-

10-Sep-2015

US TSCA



California Proposition 65This product does not contain any Proposition 65 chemicals.

Product code

US Federal Regulations

p. 1

1 2 0

He a lt h

Fire

Re a c t iv it y


2

1

0

E

Material Safety Data SheetThiamine HCl MSDS


Product Name: Thiamine HCl

Catalog Codes: SLT1918, SLT3211

CAS#: 67-03-8

RTECS: XI7350000

TSCA: TSCA 8(b) inventory: Thiamine HCl

CI#: Not available.

Synonym: Vitamin B1 Hydrochloride; 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride


Chemical Formula: C12H17ClN4OS.HCl







Thiamine HCl 67-03-8 100

Toxicological Data on Ingredients: Thiamine HCl: ORAL (LD50): Acute: 3710 mg/kg [Rat]. 8224 mg/kg [Mouse].


Potential Acute Health Effects:Very hazardous in case of eye contact (irritant). Hazardous in case of ingestion, of inhalation. Slightly hazardous in case ofskin contact (irritant). Inflammation of the eye is characterized by redness, watering, and itching.

Potential Chronic Health Effects:Very hazardous in case of eye contact (irritant). Hazardous in case of ingestion, of inhalation. Slightly hazardous in case ofskin contact (irritant). CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Not available. TERATOGENICEFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available.


Eye Contact:

p. 2

Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelidsopen. Cold water may be used. Do not use an eye ointment. Seek medical attention.

Skin Contact:After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with runningwater and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cold water may be used.Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated clothing beforereusing.











Products of Combustion:These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), sulfur oxides (SO2, SO3...), halogenatedcompounds.










Precautions:

p. 3

Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under afume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. Avoid contact with eyes In caseof insufficient ventilation, wear suitable respiratory equipment If ingested, seek medical advice immediately and show thecontainer or the label.








Physical state and appearance: Solid. (Powdered solid.)







Melting Point: Decomposes. (248°C or 478.4°F)











p. 4









Polymerization: No.


Routes of Entry: Eye contact. Inhalation. Ingestion.



Other Toxic Effects on Humans:Hazardous in case of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant).











Waste Disposal:





p. 5


Federal and State Regulations: TSCA 8(b) inventory: Thiamine HCl



WHMIS (Canada): CLASS D-2B: Material causing other toxic effects (TOXIC).

DSCL (EEC): R41- Risk of serious damage to eyes.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 1

Reactivity: 0



Health: 2

Flammability: 1

Reactivity: 0

Specific hazard:

Protective Equipment:Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respiratorwhen ventilation is inadequate. Splash goggles.




Created: 10/10/2005 12:03 AM

Last Updated: 05/21/2013 12:00 PM


Material Safety Data SheetTris hydrochloride

1

1

0


Product Name: Tris hydrochloride

Catalog Code: 42020224-1

CAS#: 1185-53-1


TSCA: TSCA 8(b) inventory : Tris hydrochloride

CI#: Not available.

Synonym: 2−Amino−2−(hydroxymethyl)−1,3−propanediol, hydrochloride; Tris HCl; Tris (hydroxymethyl) aminomethane Hydrochloride

Chemical Name: Tris hydrochloride

Chemical Formula: C4H12NO3CI








Composition:

Name CAS# % by WeightTris(hydroxymethyl)aminomethane hydrochloride 1185-53-1 >99


Not available.


Potential Acute Health Effects: Harmful if swallowed. May cause irritation to skin, eyes and respiratory tract.




110

1




Eye Contact: In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Skin Contact: In case of contact, immediately wash skin with soap and copious amounts of water.

Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention.

Inhalation: If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.


Ingestion: If swallowed, wash out mouth with water provided person is conscious. Call a physician.







Product of Combustion: Carbon monoxide, carbon dioxide, nitrogen oxides.





LARGE FIRE: Water spray, dry chemical, alcohol foam, or carbon dioxide.


Special Remarks on Explosion Hazards: Product does not present an explosion hazard.

6: Accidental Release MeasuresSmall Spill: Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventillate area and wash spill site after material pick up is complete.Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.


Precautions: Avoid contact with eyes, skin and clothing. Avoid breathing dust.

2

Storage: Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage and moisture. Separate from incompatibilities.






Physical State and Appearance: Solid

Odor: Odorless

Taste: Colorless.



pH(1% soln/water): 4.2-4.9


Melting Point: 150 − 151 ºC (302 − 304 ºF)










Solubility: Soluble in water.


Stability: Stable.


3


Incompatibility with various substances: Strong oxidizing agents.






Routes of Entry: Skin contact. Eye contact. Ingestion. Inhalation.


Not available.


Other Toxic Effects on Humans: Skin Contact: May cause skin irritation.Skin Absorption: May be harmful if absorbed through the skin.Eye Contact: May cause eye irritation.Inhalation: May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.Ingestion: May be harmful if swallowed.











Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations.



4




Federal and State Regulations: TSCA 8(b) inventory : Tris-HCl





HMIS(U.S.A):

Health Hazard: 1

Fire Hazard: 1

Reactivity: 0



Health: 1

Flammability: 1

Reactivity: 0

Specific hazard:

Protective Equipment: Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Safety goggles.




Created: 23/06/2006 2:58:31 PM

Last Updated: 07/01/2009 11:40:41 AM

Disclaimer


The information above is believed to be accurate and represents the best information currently available to us. However,we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes.In no event shall Bio-World.com be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect,incidental,consequential or exemplary damages, howsoever arising,

5

even if Bio-World.com has been advised of the possibility of such damages.

6

Material Safety Data SheetTris, Ultra-pure grade

2

0

0


Product Name: Tris, Ultra-pure grade

Catalog Code: 42020236-1, 42020236-2

CAS#: 77-86-1

RTECS: TY2900000

TSCA: TSCA 8(b) inventory : Tris (Hydroxymethyl) Aminomethane

CI#: Not available.

Synonym: 2-Amino-2-(hydroxymethyl)propane-1,3-diol; 2-Amino-2-(hydroxymethyl)-1,3-propanediol; 2-Amino-2-methylol-1,3-propanediol; Aminotrimethylolmethane; Aminotris(hydroxymethyl)methane; Methylamine, 1,1,1-tris(hydroxymethyl)-; Trimethylolaminomethane; Tris (buffering agent); Trisamine; Tris-amino; Trisaminol; Tris buffer; Tris-hydroxymethylaminomethane; Tris(hydroxymethyl)methanamine; Tris(hydroxymethyl)methylamine; Tromethamine; Tromethane; Tromethanmin

Chemical Name: Tris (Hydroxymethyl) Aminomethane

Chemical Formula: C4H11NO3








Composition:

Name CAS# % by WeightTris (Hydroxymethyl) Aminomethane 77-86-1 >99.8


LD50 (Oral, Rat): 5900 mg/kg LD50 (Intravenous, Rat): 1800 mg/kg LD50 (Intravenous, Mouse): 1210 mg/kg


Potential Acute Health Effects: Irritating to eyes, respiratory system and skin.

200

1







Eye Contact: In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Skin Contact: In case of contact, immediately wash skin with soap and copious amounts of water.

Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention.

Inhalation: If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.


Ingestion: If swallowed, wash out mouth with water provided person is conscious. Call a physician.







Product of Combustion: Carbon monoxide, Carbon dioxide, Nitrogen oxides.





LARGE FIRE: Water spray. Carbon dioxide, dry chemical powder, or appropriate foam.



6: Accidental Release MeasuresSmall Spill: Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site

2

after material pickup is complete.Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.


Precautions: Do not breathe dust. Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeated exposure.

Storage: Keep tightly closed.






Physical State and Appearance: Solid (Crystalline powder).




Color: White.

pH(1% soln/water): 10.5 - 12.0

Boiling Point: 219.0 - 220.0 °C

Melting Point: 171.2 - 172.3 °C










Solubility: Soluble in water.

3


Stability: Stable.


Conditions of Instability: Moisture.

Incompatibility with various substances: Strong oxidizing agents.






Routes of Entry: Skin contact. Eye contact. Ingestion. Inhalation.


LD50 (Oral, Rat): 5900 mg/kg

LD50 (Intravenous, Rat): 1800 mg/kg LD50 (Intravenous, Mouse): 1210 mg/kg


Other Toxic Effects on Humans: Skin Contact: Causes skin irritation.Skin Absorption: May be harmful if absorbed through the skin.Eye Contact: Causes eye irritation.Inhalation: May be harmful if inhaled. Material is irritating to mucous membranes and upper respiratory tract.Ingestion: May be harmful if swallowed.











4

Waste Disposal: Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state, and local environmental regulations.






Federal and State Regulations: TSCA 8(b) inventory : Tris (Hydroxymethyl) Aminomethane

Other Regulations: EU ADDITIONAL CLASSIFICATION Symbol of Danger: Xi Indication of Danger: Irritant.R: 36/37/38 Risk Statements: Irritating to eyes, respiratory system and skin.S: 26-36 Safety Statements: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.




HMIS(U.S.A):

Health Hazard: 2

Fire Hazard: 0

Reactivity: 0



Health: 2

Flammability: 0

Reactivity: 0

Specific hazard:

Protective Equipment: Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Safety goggles.



5


Created: 15/12/2006 1:03:22 PM

Last Updated: 07/01/2009 11:42:30 AM

Disclaimer


The information above is believed to be accurate and represents the best information currently available to us. However,we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes.In no event shall Bio-World.com be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect,incidental,consequential or exemplary damages, howsoever arising, even if Bio-World.com has been advised of the possibility of such damages.

6

________________________________________________________________________________________________________________

SAFETY DATA SHEET



Eyes May cause eye irritation with susceptible persons.Skin May cause skin irritation in susceptible persons.Inhalation May be harmful by inhalation.Ingestion May be harmful if swallowed.

Signal Wordnot hazardous

Health Hazard


not hazardous


Product name UltraPure™ 20X SSC

Physical Hazards

________________________________________________________________________________________________________________

not hazardous





866-536-0631301-431-8585Outside of the U.S. +1-301-431-8585

Page 1 / 5

Product code

30-Oct-2013

15557036





Product code

Life Technologies5250 Mainway DriveBurlington, ONTCANADA L7L 6A4800/263-6236

Sensitization none

6. Ac c ident a l re lease m easures

Personal precautions Use personal protective equipment.Methods for cleaning up Soak up with inert absorbent material.

Mutagenic effects

4. Fi rs t a id m easures


Target Organ Effects

Prevent further leakage or spillage if safe to do so.


Skin contact Rinse with plenty of water. If symptoms arise, call a physician.

none


Specific effects

Eye contact Rinse immediately with plenty of water, also under the eyelids, for at least 15minutes. If symptoms persist, call a physician.

7. Handl ing and s t orage

Ingestion Never give anything by mouth to an unconscious person. If symptoms persist, calla physician. Do not induce vomiting without medical advice.

Inhalation Move to fresh air. If symptoms persist, call a physician. If not breathing, giveartificial respiration.

Notes to physician Treat symptomatically.

5. Fi re-f ight ing m easures


HMIS

________________________________________________________________________________________________________________




none

Health 0


15557036

Reactivity 0

Revision DateProduct name UltraPure™ 20X SSC

Page 2 / 530-Oct-2013



Flammability

Product code

0

Prevent product from entering drains.

Oxidizing properties No information available.

9. Phys ic a l and c hem ic a l proper t ies



In case of insufficient ventilation wear suitable respiratory equipment.

Storage

General Information

10. St ab i l i t y and reac t iv i t y

Exposure limits


Engineering measures

Form

Materials to avoid No dangerous reaction known under conditions of normal use.

liquid


None under normal use

Appearance



Ensure adequate ventilation, especially in confined areas.

Keep in a dry, cool and well-ventilated place.

Odor

11. Tox ic o log ic a l in form at ion


Hand protection Impervious gloves.

Acute toxicity

8. Ex posure c ont ro ls /personal prot ec t ion

Eye protection Safety glasses with side-shields.

Handling

Skin and body protection. Lightweight protective clothing.


________________________________________________________________________________________________________________

Hygiene measures Handle in accordance with good industrial hygiene and safety practice.

Always wear reccommended Personal Protective Equipment. No special handlingadvice required.


15557036

We are not aware of any national exposure limit.


Revision Date



Melting point/range

Page 3 / 5

°C no data available

Autoignition temperature°C no data available

Boiling Point/Range

30-Oct-2013


Flash point



Product code



13. Disposal c ons iderat ions


Sensitization

Dispose of in accordance with local regulations.

none

14. Transpor t in form at ion

Inhalation

Target Organ Effects No known effects under normal use conditions.

May be harmful by inhalation.

IATA


Proper shipping name Not classified as dangerous in the meaning of transport regulationsHazard class noneSubsidiary Class none

Ingestion May be harmful if swallowed.

Packing group none

12. Ec olog ic a l in form at ion

UN-No None

not hazardous

________________________________________________________________________________________________________________

Ecotoxicity effects No information available.

Eyes

Mobility No information available.

Carcinogenic effects none

Biodegradation Inherently biodegradable

15557036

May cause eye irritation with susceptible persons.

Revision Date

Bioaccumulation


Does not bioaccumulate.

Page 4 / 5

Mutagenic effects none

30-Oct-2013


Product code


The above information was acquired by diligent search and/or investigation and the recommendations are based onprudent application of professional judgment. The information shall not be taken as being all inclusive and is to beused only as a guide. All materials and mixtures may present unkown hazards and should be used with caution.Since the Company cannot control the actual methods, volumes, or conditions of use, the Company shall not be heldliable for any damages or losses resulting from the handling or from contact with the product as described herein.THE INFORMATION IN THIS MSDS DOES NOT CONSTITUTE A WARRENTY, EXPRESSED OR IMPLIED,INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PUPOSE.




WHMIS Hazard ClassNon-controlled

________________________________________________________________________________________________________________

This product has been classified according to the hazard criteria of the CPR and the MSDS contains all of the information requiredby the CPR






Product name UltraPure™ 20X SSCPage 5 / 5


30-Oct-2013

California Proposition 65This product does not contain chemicals listed under Proposition 65


Product code

irvine scientific material safety data … safety data sheet version: 02 hepes buffer solution 1 m...

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